Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0526 | 0.5962 | 1 |
Giardia lamblia | Cysteine protease | 0.0116 | 0.1094 | 0.2534 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0282 | 0.3067 | 0.2956 |
Plasmodium vivax | unspecified product | 0.0282 | 0.3067 | 0.5012 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0348 | 0.3848 | 0.6357 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0047 | 0.0277 | 0.0277 |
Giardia lamblia | Cathepsin L-like protease | 0.0116 | 0.1094 | 0.2534 |
Brugia malayi | Cathepsin L-like precursor | 0.0526 | 0.5962 | 0.5962 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Plasmodium vivax | vivapain-2 | 0.0526 | 0.5962 | 1 |
Onchocerca volvulus | 0.0526 | 0.5962 | 1 | |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0047 | 0.0277 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0866 | 1 | 1 |
Giardia lamblia | Cysteine protease | 0.0116 | 0.1094 | 0.2534 |
Echinococcus granulosus | cathepsin b | 0.0866 | 1 | 1 |
Onchocerca volvulus | 0.0526 | 0.5962 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.3021 | 0.3021 |
Onchocerca volvulus | 0.0278 | 0.3021 | 0.4933 | |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0035 | 0.0131 | 0.0131 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0282 | 0.3067 | 0.5012 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0282 | 0.3067 | 0.3067 |
Schistosoma mansoni | cathepsin C | 0.0116 | 0.1094 | 0.1094 |
Entamoeba histolytica | cysteine protease, putative | 0.0116 | 0.1094 | 0.1611 |
Entamoeba histolytica | hypothetical protein | 0.0116 | 0.1094 | 0.1611 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0282 | 0.3067 | 0.5012 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0282 | 0.3067 | 0.5012 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0116 | 0.1094 | 0.1094 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0047 | 0.0277 | 0.0277 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0282 | 0.3067 | 0.2956 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0282 | 0.3067 | 0.3067 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0277 |
Onchocerca volvulus | 0.0526 | 0.5962 | 1 | |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0205 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0348 | 0.3848 | 0.3749 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Giardia lamblia | Hypothetical protein | 0.0116 | 0.1094 | 0.2534 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0278 | 0.3021 | 0.3021 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | histone deacetylase | 0.0037 | 0.0158 | 0.0158 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.036 | 0.3989 | 0.3989 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Echinococcus granulosus | cathepsin l1 | 0.036 | 0.3989 | 0.3892 |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0526 | 0.5962 | 0.5962 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0526 | 0.5962 | 0.5897 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1094 | 0.1094 |
Schistosoma mansoni | histone deacetylase | 0.0037 | 0.0158 | 0.0158 |
Giardia lamblia | Cathepsin B precursor | 0.0348 | 0.3848 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0116 | 0.1094 | 0.2534 |
Loa Loa (eye worm) | cathepsin B | 0.0348 | 0.3848 | 0.3848 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1094 | 0.1094 |
Brugia malayi | Cathepsin L-like precursor | 0.0526 | 0.5962 | 0.5962 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0116 | 0.1094 | 0.1094 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0205 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0116 | 0.1094 | 0.095 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0047 | 0.0277 | 0.0121 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0278 | 0.3021 | 0.3021 |
Loa Loa (eye worm) | fibroinase | 0.0526 | 0.5962 | 0.5962 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0116 | 0.1094 | 0.1611 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0116 | 0.1094 | 0.1094 |
Giardia lamblia | Cathepsin L precursor | 0.0116 | 0.1094 | 0.2534 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | cathepsin s | 0.0166 | 0.169 | 0.169 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0116 | 0.1094 | 0.1094 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0526 | 0.5962 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0526 | 0.5962 | 0.5962 |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0116 | 0.1094 | 0.1611 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | Histone deacetylase 1 | 0.0037 | 0.0158 | 0.0158 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0526 | 0.5962 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0166 | 0.169 | 0.169 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0526 | 0.5962 | 0.5962 |
Giardia lamblia | Cathepsin L-like protease | 0.0116 | 0.1094 | 0.2534 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0116 | 0.1094 | 0.1611 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0116 | 0.1094 | 0.1094 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0037 | 0.0158 | 0.0158 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0116 | 0.1094 | 0.1611 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0282 | 0.3067 | 0.3067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.036 | 0.3989 | 0.6599 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0047 | 0.0277 | 0.0121 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.0277 | 0.0205 |
Echinococcus granulosus | cathepsin b | 0.0866 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0116 | 0.1094 | 0.2534 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0047 | 0.0277 | 0.0121 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0526 | 0.5962 | 1 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0047 | 0.0277 | 0.0121 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0047 | 0.0277 | 0.0121 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Loa Loa (eye worm) | ctsf protein | 0.0526 | 0.5962 | 0.5962 |
Loa Loa (eye worm) | hypothetical protein | 0.0866 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | serotonin transporter b | 0.0278 | 0.3021 | 0.3021 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0282 | 0.3067 | 0.5012 |
Echinococcus multilocularis | cysteine protease | 0.0526 | 0.5962 | 0.5897 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0116 | 0.1094 | 0.1094 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0037 | 0.0158 | 0.0158 |
Giardia lamblia | Cathepsin B precursor | 0.0116 | 0.1094 | 0.2534 |
Loa Loa (eye worm) | hypothetical protein | 0.036 | 0.3989 | 0.3989 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0047 | 0.0277 | 0.0121 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0037 | 0.0158 | 0.0158 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | Cathepsin L-like precursor | 0.0166 | 0.169 | 0.169 |
Plasmodium falciparum | transporter, putative | 0.0047 | 0.0277 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.3021 | 0.3021 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0278 | 0.3021 | 0.3021 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0866 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Toxoplasma gondii | cathepsin CPC1 | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0277 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0277 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0116 | 0.1094 | 0.1611 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0282 | 0.3067 | 0.5012 |
Echinococcus multilocularis | cathepsin b | 0.0866 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0526 | 0.5962 | 0.5897 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0116 | 0.1094 | 0.1611 |
Onchocerca volvulus | Cathepsin L homolog | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0037 | 0.0158 | 0.0158 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0526 | 0.5962 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0526 | 0.5962 | 0.5897 |
Plasmodium vivax | vivapain-1 | 0.0282 | 0.3067 | 0.5012 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0116 | 0.1094 | 0.1611 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0282 | 0.3067 | 0.5012 |
Giardia lamblia | Cathepsin L precursor | 0.0116 | 0.1094 | 0.2534 |
Entamoeba histolytica | cysteine proteinase, putative | 0.036 | 0.3989 | 0.6599 |
Brugia malayi | Cathepsin L-like precursor | 0.0526 | 0.5962 | 0.5962 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0116 | 0.1094 | 0.1611 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0116 | 0.1094 | 0.1611 |
Loa Loa (eye worm) | hypothetical protein | 0.0278 | 0.3021 | 0.3021 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0526 | 0.5962 | 0.5962 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0277 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0526 | 0.5962 | 0.5897 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Onchocerca volvulus | 0.0526 | 0.5962 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0116 | 0.1094 | 0.1094 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0866 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0116 | 0.1094 | 0.2534 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0526 | 0.5962 | 0.5962 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0116 | 0.1094 | 0.2534 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0116 | 0.1094 | 0.2534 |
Onchocerca volvulus | Cathepsin F homolog | 0.0526 | 0.5962 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0526 | 0.5962 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0282 | 0.3067 | 0.2956 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0116 | 0.1094 | 0.1094 |
Echinococcus multilocularis | serotonin transporter | 0.0278 | 0.3021 | 0.2909 |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Giardia lamblia | Encystation-specific protease | 0.0116 | 0.1094 | 0.2534 |
Giardia lamblia | Cathepsin L precursor | 0.0116 | 0.1094 | 0.2534 |
Brugia malayi | histone deacetylase 11 | 0.0037 | 0.0158 | 0.0158 |
Entamoeba histolytica | cysteine protease, putative | 0.0116 | 0.1094 | 0.1611 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Loa Loa (eye worm) | hypothetical protein | 0.036 | 0.3989 | 0.3989 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0278 | 0.3021 | 0.3021 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.036 | 0.3989 | 0.6599 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0037 | 0.0158 | 0.0158 |
Onchocerca volvulus | 0.0047 | 0.0277 | 0.0205 | |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1094 | 0.1094 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0116 | 0.1094 | 0.1611 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.0277 | 0.0205 |
Onchocerca volvulus | 0.0047 | 0.0277 | 0.0205 | |
Giardia lamblia | Cathepsin B precursor | 0.0348 | 0.3848 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0282 | 0.3067 | 0.3067 |
Onchocerca volvulus | 0.0526 | 0.5962 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0166 | 0.169 | 0.1556 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0166 | 0.169 | 0.1556 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0526 | 0.5962 | 0.5897 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0116 | 0.1094 | 0.1611 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0121 |
Giardia lamblia | Cysteine protease | 0.0116 | 0.1094 | 0.2534 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0282 | 0.3067 | 0.2956 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0047 | 0.0277 | 0.0205 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0282 | 0.3067 | 0.2956 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Onchocerca volvulus | 0.0526 | 0.5962 | 1 | |
Plasmodium falciparum | serine repeat antigen 2 | 0.0116 | 0.1094 | 0.1611 |
Giardia lamblia | Cathepsin B precursor | 0.0116 | 0.1094 | 0.2534 |
Brugia malayi | cathepsin L-like precursor | 0.036 | 0.3989 | 0.3989 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Echinococcus multilocularis | cysteine protease | 0.0526 | 0.5962 | 0.5897 |
Entamoeba histolytica | cysteine protease, putative | 0.0116 | 0.1094 | 0.1611 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.169 | 0.169 |
Echinococcus multilocularis | cathepsin L | 0.0116 | 0.1094 | 0.095 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Giardia lamblia | Cathepsin B precursor | 0.0348 | 0.3848 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0526 | 0.5962 | 0.5897 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.036 | 0.3989 | 0.3989 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0526 | 0.5962 | 0.5962 |
Plasmodium vivax | unspecified product | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0166 | 0.169 | 0.169 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.036 | 0.3989 | 0.3892 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0526 | 0.5962 | 0.5962 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0116 | 0.1094 | 0.1611 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0526 | 0.5962 | 0.5897 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0866 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0282 | 0.3067 | 0.5012 |
Echinococcus multilocularis | cathepsin b | 0.0866 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0116 | 0.1094 | 0.1611 |
Plasmodium vivax | unspecified product | 0.0166 | 0.169 | 0.2639 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0037 | 0.0158 | 0.0158 |
Echinococcus multilocularis | cathepsin L | 0.0282 | 0.3067 | 0.2956 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0121 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0037 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.169 | 0.169 |
Toxoplasma gondii | cathepsin CPL | 0.0526 | 0.5962 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0526 | 0.5962 | 0.5897 |
Toxoplasma gondii | cathepsin B | 0.0348 | 0.3848 | 0.6357 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1094 | 0.1094 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0047 | 0.0277 | 0.0277 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0278 | 0.3021 | 0.3021 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Leishmania major | cysteine peptidase A (CPA) | 0.0526 | 0.5962 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0526 | 0.5962 | 0.5962 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0116 | 0.1094 | 0.1611 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0047 | 0.0277 | 0.0121 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Entamoeba histolytica | cysteine protease, putative | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | fibroinase precursor | 0.0116 | 0.1094 | 0.1094 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0047 | 0.0277 | 0.0277 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0526 | 0.5962 | 0.5897 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0348 | 0.3848 | 0.6357 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0116 | 0.1094 | 0.2534 |
Echinococcus granulosus | cathepsin L | 0.0116 | 0.1094 | 0.095 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0047 | 0.0277 | 0.0277 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0116 | 0.1094 | 0.1611 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0037 | 0.0158 | 0.0158 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0526 | 0.5962 | 0.5897 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0282 | 0.3067 | 0.5012 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Giardia lamblia | Cysteine protease | 0.0116 | 0.1094 | 0.2534 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Entamoeba histolytica | cysteine protease, putative | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0116 | 0.1094 | 0.2534 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0116 | 0.1094 | 0.1611 |
Giardia lamblia | Cathepsin B precursor | 0.0116 | 0.1094 | 0.2534 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0282 | 0.3067 | 0.5012 |
Plasmodium falciparum | amino acid transporter, putative | 0.0047 | 0.0277 | 0.0205 |
Brugia malayi | Histone deacetylase family protein | 0.0037 | 0.0158 | 0.0158 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0116 | 0.1094 | 0.1611 |
Onchocerca volvulus | 0.036 | 0.3989 | 0.6599 | |
Brugia malayi | Cathepsin L-like precursor | 0.036 | 0.3989 | 0.3989 |
Leishmania major | cathepsin L-like protease | 0.0526 | 0.5962 | 1 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0116 | 0.1094 | 0.2534 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0116 | 0.1094 | 0.095 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0158 | 0.0158 |
Onchocerca volvulus | 0.0116 | 0.1094 | 0.1611 | |
Giardia lamblia | Cathepsin L precursor | 0.0116 | 0.1094 | 0.2534 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0116 | 0.1094 | 0.1611 |
Giardia lamblia | Cathepsin B precursor | 0.0116 | 0.1094 | 0.2534 |
Brugia malayi | cathepsin L precursor | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0035 | 0.0131 | 0.0131 |
Plasmodium vivax | vivapain-2 | 0.0526 | 0.5962 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0116 | 0.1094 | 0.1611 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0205 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0526 | 0.5962 | 0.5897 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0277 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0277 |
Trypanosoma cruzi | cysteine protease, putative | 0.0282 | 0.3067 | 0.2956 |
Plasmodium vivax | amine transporter, putative | 0.0047 | 0.0277 | 0.0205 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0047 | 0.0277 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0866 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0282 | 0.3067 | 0.5012 |
Toxoplasma gondii | cathepsin CPC2 | 0.0116 | 0.1094 | 0.1611 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0277 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0037 | 0.0158 | 0.0158 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0277 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0047 | 0.0277 | 0.0277 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.036 | 0.3989 | 0.3989 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0526 | 0.5962 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0526 | 0.5962 | 0.5897 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0116 | 0.1094 | 0.1094 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0116 | 0.1094 | 0.1094 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0348 | 0.3848 | 0.3848 |
Brugia malayi | Cathepsin L-like precursor | 0.0526 | 0.5962 | 0.5962 |
Onchocerca volvulus | 0.0526 | 0.5962 | 1 | |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0037 | 0.0158 | 0.0158 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0526 | 0.5962 | 1 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0047 | 0.0277 | 0.0277 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0037 | 0.0158 | 0.0158 |
Onchocerca volvulus | Cathepsin L homolog | 0.0526 | 0.5962 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0277 | 0.0277 |
Plasmodium vivax | vivapain-3 | 0.0282 | 0.3067 | 0.5012 |
Brugia malayi | Histone deacetylase family protein | 0.0037 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0131 | 0.0131 |
Echinococcus granulosus | cathepsin L | 0.0282 | 0.3067 | 0.2956 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0166 | 0.169 | 0.169 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0116 | 0.1094 | 0.1611 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.169 | 0.169 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0037 | 0.0158 | 0.0158 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0282 | 0.3067 | 0.5012 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0348 | 0.3848 | 0.6357 |
Onchocerca volvulus | 0.0047 | 0.0277 | 0.0205 | |
Entamoeba histolytica | cysteine protease, putative | 0.0116 | 0.1094 | 0.1611 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0278 | 0.3021 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0282 | 0.3067 | 0.3067 |
Echinococcus granulosus | cysteine protease | 0.0282 | 0.3067 | 0.2956 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0116 | 0.1094 | 0.1611 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.036 | 0.3989 | 0.3989 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0526 | 0.5962 | 1 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0047 | 0.0277 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0526 | 0.5962 | 0.5962 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0282 | 0.3067 | 0.5012 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0047 | 0.0277 | 0.0277 |
Echinococcus granulosus | serotonin transporter | 0.0278 | 0.3021 | 0.2909 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0035 | 0.0131 | 0.0131 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 48 nM | Inhibition of the constrictor response to electrical stimulation in rabbit ear artery. | ChEMBL. | 2871192 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.