Detailed information for compound 335938

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 829.969 | Formula: C44H63NO14
  • H donors: 4 H acceptors: 8 LogP: 4.64 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@H]1[C@@](C)(OC(=O)C)C[C@@H]([C@]1([C@H]2O[C@@H]([C@@]1(C)O)O)O)OC(=O)CCc1ccc(cc1)NC(=O)OC(C)(C)C)C
  • InChi: 1S/C44H63NO14/c1-11-13-14-15-16-17-31(47)55-36-34-33(26(4)35(36)56-38(49)25(3)12-2)37-44(53,43(10,52)39(50)57-37)30(24-42(34,9)58-27(5)46)54-32(48)23-20-28-18-21-29(22-19-28)45-40(51)59-41(6,7)8/h12,18-19,21-22,30,34-37,39,50,52-53H,11,13-17,20,23-24H2,1-10H3,(H,45,51)/b25-12-/t30-,34+,35-,36-,37-,39-,42-,43+,44+/m0/s1
  • InChiKey: ZCLIXYZOZSWBCA-WKLUACESSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi B-box type zinc-finger protein ncl-1 0.0037 0.0194 0.0221
Schistosoma mansoni topbp1 0.0016 0.0066 0.0063
Plasmodium vivax acyl-CoA synthetase, putative 0.0029 0.0145 1
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0051 0.0058
Onchocerca volvulus 0.0014 0.0051 0.1109
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0055 0.03 0.876
Toxoplasma gondii propionate-CoA ligase 0.0012 0.0036 0.1479
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0117 0.1483
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0039 0.0206 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0014 0.0051 0.0051
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0008 0.0016 0.0016
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0018 0.0075 0.3145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0032 0.0158 0.0156
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus multilocularis dro:myosuppressin receptor 0.0014 0.0051 0.0051
Onchocerca volvulus 0.0012 0.0036 0.0689
Loa Loa (eye worm) calpain 5 0.0014 0.005 0.0058
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Echinococcus granulosus dro:myosuppressin receptor 0.0014 0.0051 0.0051
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0008 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0089 0.0505 0.0581
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0008 0.0016 0.0014
Schistosoma mansoni retinoic acid receptor RXR 0.0008 0.0013 0.0011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0184
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0016 0.0066 0.2746
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0092 0.1784
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0014 0.0051 0.0056
Echinococcus multilocularis muscleblind protein 0.0242 0.144 0.144
Schistosoma mansoni amine GPCR 0.0014 0.0051 0.0049
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0014 0.0051 0.0051
Echinococcus granulosus allatostatin A receptor 0.0014 0.0051 0.0051
Schistosoma mansoni patched 1 0.0038 0.0197 0.0195
Echinococcus multilocularis G protein coupled receptor 139 0.0014 0.0051 0.0051
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0051 0.0051
Trypanosoma brucei calpain-like protein, putative 0.002 0.0087 0.2607
Echinococcus granulosus neuropeptide receptor A26 0.0014 0.0051 0.0051
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.2607
Plasmodium vivax acetyl-CoA synthetase, putative 0.0012 0.0036 0.1543
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0061 0.0337 1
Schistosoma mansoni hypothetical protein 0.026 0.1549 0.1547
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0375 0.2251 0.2585
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0012 0.0036 0.1048
Loa Loa (eye worm) hypothetical protein 0.0029 0.0145 0.0167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni amine GPCR 0.0014 0.0051 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0008 0.0013 0.0015
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0008 0.0016 0.0184
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0036 0.0621
Brugia malayi calpain 5 0.0014 0.005 0.0056
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni neuropeptide receptor 0.0014 0.0051 0.0049
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0078 0.2347
Brugia malayi Pax transcription activation domain interacting protein 0.0016 0.0066 0.0073
Echinococcus granulosus peptide allatostatin:somatostatin 0.0014 0.0051 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0066 0.082
Brugia malayi putative neuropeptide receptor NPR1 0.0014 0.0051 0.0056
Onchocerca volvulus 0.0012 0.0036 0.0689
Echinococcus granulosus dnaJ subfamily B 0.026 0.1549 0.1549
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS17 0.0037 0.0194 0.554
Echinococcus multilocularis L aminoadipate semialdehyde 0.0064 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni hypothetical protein 0.0296 0.1774 0.1772
Giardia lamblia Cathepsin B precursor 0.0044 0.0233 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.2607
Plasmodium vivax calpain, putative 0.002 0.0087 0.547
Loa Loa (eye worm) calpain family protein 1 0.0053 0.0287 0.033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0016 0.0066 0.082
Brugia malayi hypothetical protein 0.0083 0.0472 0.054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0008 0.0013 0.0015
Onchocerca volvulus 0.0014 0.0051 0.1109
Echinococcus granulosus biogenic amine 5HT receptor 0.0014 0.0051 0.0051
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0014 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0083 0.0472 0.9335
Brugia malayi hypothetical protein 0.0016 0.0063 0.007
Giardia lamblia Cathepsin B precursor 0.0044 0.0233 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0018 0.0075 0.9399
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0014 0.0051 0.1109
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0012 0.0036 0.1479
Brugia malayi cathepsin B-like cysteine proteinase 0.0133 0.0776 0.089
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0051 0.0051
Leishmania major acetyl-CoA synthetase, putative 0.0012 0.0036 0.105
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0014 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0013 0.0012
Echinococcus multilocularis somatostatin receptor 0.0014 0.0051 0.0051
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0117 0.8009
Loa Loa (eye worm) hypothetical protein 0.1433 0.8703 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0002
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1433 0.8703 1
Brugia malayi putative neuropeptide receptor 0.0014 0.0051 0.0056
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0039 0.0206 0.5924
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Echinococcus multilocularis replication factor c subunit 1 0.0016 0.0066 0.0066
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0006 0.0003 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0012 0.0036 0.0039
Onchocerca volvulus 0.0014 0.0051 0.1109
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0014 0.0051 0.0049
Loa Loa (eye worm) B-box zinc finger family protein 0.0037 0.0194 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0066 0.2746
Trypanosoma cruzi kinesin, putative 0.0014 0.005 0.0625
Echinococcus granulosus Protein patched homolog 1 0.0038 0.0197 0.0197
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0078 0.0987
Schistosoma mansoni biogenic amine receptor 0.0014 0.0051 0.0049
Entamoeba histolytica hypothetical protein 0.0083 0.0472 0.9335
Entamoeba histolytica acyl-coA synthetase, putative 0.0039 0.0206 0.4056
Schistosoma mansoni transcription factor LCR-F1 0.0083 0.0472 0.047
Loa Loa (eye worm) hypothetical protein 0.0037 0.0194 0.0223
Schistosoma mansoni amine GPCR 0.0014 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi neuropeptide F receptor 0.0014 0.0051 0.0056
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0014 0.0051 0.0051
Brugia malayi Nuclear hormone receptor-like 1 0.0008 0.0013 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0039 0.0206 0.5654
Echinococcus granulosus neuropeptide s receptor 0.0014 0.0051 0.0051
Echinococcus granulosus tm gpcr rhodopsin 0.0517 0.3119 0.3119
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0036 0.0621
Echinococcus multilocularis FTZ F1 alpha 0.0008 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi nuclear hormone receptor 0.0008 0.0013 0.0012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0013 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.1433 0.8703 0.8703
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0059 0.0328 0.6466
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0021 0.0095 0.0109
Schistosoma mansoni hypothetical protein 0.0014 0.0051 0.0049
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0051 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Toxoplasma gondii thioredoxin reductase 0.0024 0.0112 0.476
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0008 0.0016 0.1554
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0012 0.0036 0.0621
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0051 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0066 0.2746
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0051 0.0058
Trypanosoma cruzi trypanothione reductase, putative 0.0008 0.0016 0.0184
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0059 0.0328 0.0328
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS18 0.0037 0.0194 0.554
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.001 0.0026 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Echinococcus granulosus calpain 7 C02 family 0.002 0.0087 0.0087
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0044 0.0233 0.0231
Schistosoma mansoni opsin-like receptor 0.0014 0.0051 0.0049
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0051 0.0049
Onchocerca volvulus 0.0012 0.0036 0.0689
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0044 0.0233 0.7098
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0078 0.1938
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0012 0.0036 0.0441
Echinococcus granulosus g protein coupled receptor 0.0014 0.0051 0.0051
Trichomonas vaginalis glutathione reductase, putative 0.0008 0.0016 0.0618
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0078 0.3271
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0008 0.0016 0.0016
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0039 0.0206 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0024 0.0112 0.2985
Echinococcus granulosus g-protein coupled receptor 0.0014 0.0051 0.0051
Plasmodium falciparum thioredoxin reductase 0.0024 0.0112 0.7672
Mycobacterium tuberculosis Probable conserved membrane protein 0.0037 0.0194 0.554
Schistosoma mansoni opsin-like receptor 0.0014 0.0051 0.0049
Schistosoma mansoni hypothetical protein 0.0037 0.0194 0.0192
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0013 0.0012
Loa Loa (eye worm) RING finger protein nhl-1 0.0037 0.0194 0.0223
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0078 0.0078
Plasmodium falciparum glutathione reductase 0.0008 0.0016 0.0995
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0021 0.0092 0.2759
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0206 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0078 0.3307
Brugia malayi CHE-14 protein 0.0038 0.0197 0.0224
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0055 0.03 0.8837
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0012 0.0036 0.0036
Echinococcus multilocularis allatostatin A receptor 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0037 0.0194 0.0223
Echinococcus granulosus cathepsin b 0.0133 0.0776 0.0776
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0059 0.0328 0.0326
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0008 0.0016 0.1554
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0008 0.0016 0.0184
Leishmania major 4-coumarate:coa ligase-like protein 0.0039 0.0206 0.6273
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0033 0.0166 0.0191
Trichomonas vaginalis replication factor C large subunit, putative 0.0016 0.0066 0.2747
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0059 0.0328 0.0328
Schistosoma mansoni cpg binding protein 0.0019 0.0083 0.0081
Loa Loa (eye worm) calpain D 0.0006 0.0002 0.0002
Echinococcus granulosus geminin 0.0296 0.1774 0.1774
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0059 0.0328 0.0376
Echinococcus multilocularis calpain 0.002 0.0087 0.0087
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0761 0.4606 0.5291
Echinococcus granulosus nibrin 0.0016 0.0066 0.0066
Schistosoma mansoni chromosome transmission fidelity factor 0.0016 0.0066 0.0063
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0013 0.0011
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0059 0.0328 0.4204
Loa Loa (eye worm) CXXC zinc finger family protein 0.0018 0.0077 0.0088
Echinococcus multilocularis cathepsin b 0.0133 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0044 0.0237 0.0272
Plasmodium falciparum replication factor C subunit 1, putative 0.0016 0.0066 0.4427
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0201 0.0199
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0029 0.0145 0.4026
Trypanosoma brucei antigen, putative 0.002 0.0087 0.2607
Echinococcus granulosus cathepsin b 0.0133 0.0776 0.0776
Brugia malayi Thioredoxin reductase 0.0024 0.0112 0.0126
Loa Loa (eye worm) steroid hormone receptor 0.0008 0.0013 0.0015
Giardia lamblia Haloacid dehalogenase-like hydrolase family 0.0037 0.0194 0.8193
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0051 0.0051
Trypanosoma brucei calpain-like protein, putative 0.002 0.0087 0.2607
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0206 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0012 0.0036 0.0039
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0014 0.0051 0.0056
Schistosoma mansoni hypothetical protein 0.0037 0.0194 0.0192
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0059 0.0328 0.0374
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Mycobacterium tuberculosis Probable dehydrogenase 0.0055 0.03 0.8837
Schistosoma mansoni amine GPCR 0.0014 0.0051 0.0049
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0302 0.03
Schistosoma mansoni peptidylglycine monooxygenase 0.0761 0.4606 0.4605
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0312 0.1866 0.1866
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0008 0.0013 0.0015
Schistosoma mansoni hypothetical protein 0.0083 0.0472 0.047
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0012 0.0036 0.0441
Loa Loa (eye worm) hypothetical protein 0.0029 0.0145 0.0167
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Trichomonas vaginalis rotamase, putative 0.0021 0.0092 0.3886
Echinococcus multilocularis sterol regulatory element binding protein 0.0038 0.0197 0.0197
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0078 0.4813
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0013 0.0012
Mycobacterium tuberculosis Probable oxidoreductase 0.0061 0.0337 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0133 0.0776 0.0774
Giardia lamblia Cathepsin B precursor 0.0044 0.0233 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0037 0.0194 0.5895
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0066 0.2746
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi Hypothetical RING finger protein F54G8.4 in chromosome III 0.0037 0.0194 0.0221
Leishmania major trypanothione reductase 0.0024 0.0112 0.3379
Echinococcus multilocularis G-protein coupled receptor, putative 0.0014 0.0051 0.0051
Echinococcus granulosus g protein coupled receptor 0.0014 0.0051 0.0051
Echinococcus granulosus muscleblind protein 0.0242 0.144 0.144
Echinococcus granulosus neuropeptide FF receptor 2 0.0014 0.0051 0.0051
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0008 0.0013 0.0013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0078 0.0987
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.1096
Schistosoma mansoni hypothetical protein 0.0011 0.0033 0.0031
Schistosoma mansoni hypothetical protein 0.0014 0.0051 0.0049
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.135 0.8197 0.8197
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0008 0.0013 0.0013
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0008 0.0016 0.0995
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0136 0.372
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus multilocularis transcription factor Dp 1 0.0034 0.0175 0.0175
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0438
Loa Loa (eye worm) calpain 0.002 0.0087 0.01
Plasmodium vivax glutathione reductase, putative 0.0024 0.0112 0.7415
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0136 0.372
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0006 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.0039 0.0206 0.0237
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0012 0.0036 0.105
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0008 0.0013 0.0012
Toxoplasma gondii exonuclease III APE 0.0019 0.0078 0.3307
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0206 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0075
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0008 0.0016 0.0995
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0117 0.7789
Giardia lamblia Replication factor C, subunit 1 0.0016 0.0066 0.2269
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Echinococcus multilocularis geminin 0.0296 0.1774 0.1774
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0021 0.0092 0.116
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0008 0.0013 0.0013
Trypanosoma brucei cysteine peptidase C (CPC) 0.0044 0.0233 0.7098
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0087 0.1096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Schistosoma mansoni niemann-pick C1 (NPC1) 0.009 0.0514 0.0512
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0066 0.082
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0059 0.0328 0.4204
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0051 0.0051
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0008 0.0013 0.0015
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0012 0.0036 0.0441
Onchocerca volvulus 0.0014 0.0051 0.1109
Echinococcus granulosus brain tumor protein 0.0037 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus multilocularis thyroid hormone receptor alpha 0.0008 0.0013 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.1645 1 1
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Brugia malayi GnHR receptor homolog 0.0014 0.0051 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0008 0.0013 0.0012
Schistosoma mansoni myosin xvIII 0.0014 0.0051 0.0049
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0008 0.0013 0.0011
Brugia malayi Dopamine receptor protein 1 0.0014 0.0051 0.0056
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0064 0.0354 0.0404
Echinococcus multilocularis neuropeptide receptor A26 0.0014 0.0051 0.0051
Schistosoma mansoni DNA ligase IV 0.0016 0.0066 0.0063
Echinococcus granulosus hypothetical protein 0.0014 0.0051 0.0051
Schistosoma mansoni topbp1 0.0016 0.0066 0.0063
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0012 0.0036 0.1048
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0051 0.0051
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0136 0.372
Echinococcus granulosus alpha 1A adrenergic receptor 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0242 0.144 0.1655
Echinococcus multilocularis cathepsin b 0.0133 0.0776 0.0776
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0014 0.0051 0.0056
Entamoeba histolytica hypothetical protein 0.0018 0.0075 0.1444
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0055 0.03 0.8837
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0008 0.0013 0.0013
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0302 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0044 0.0233 1
Loa Loa (eye worm) calpain family protein 1 0.0039 0.0202 0.0233
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0012 0.0036 0.0042
Trypanosoma cruzi FHA domain containing protein, putative 0.0016 0.0066 0.082
Schistosoma mansoni coup transcription factor 0.0008 0.0013 0.0011
Brugia malayi hypothetical protein 0.0016 0.0066 0.0073
Trypanosoma cruzi calpain cysteine peptidase, putative 0.002 0.0087 0.1096
Schistosoma mansoni calpain-7 (C02 family) 0.002 0.0087 0.0085
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0012 0.0036 0.1048
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0016 0.0066 0.2747
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0075
Brugia malayi larval opioid receptor 0.0014 0.0051 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0013 0.0012
Onchocerca volvulus 0.0016 0.0066 0.1548
Brugia malayi Serotonin receptor 0.0014 0.0051 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0032 0.0158 0.0156
Schistosoma mansoni alpha-1 adrenergic receptor 0.0014 0.0051 0.0049
Schistosoma mansoni neuropeptide f receptor 76f 0.0014 0.0051 0.0049
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0117 0.3527
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.2607
Brugia malayi nuclear receptor NHR-88 0.0008 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0008 0.0013 0.0012
Schistosoma mansoni biogenic amine receptor 0.0014 0.0051 0.0049
Brugia malayi photoreceptor-specific nuclear receptor 0.0008 0.0013 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0036 0.0621
Schistosoma mansoni hypothetical protein 0.0014 0.0051 0.0049
Schistosoma mansoni amine GPCR 0.0014 0.0051 0.0049
Schistosoma mansoni biogenic amine receptor 0.0014 0.0051 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Echinococcus multilocularis hypothetical protein 0.002 0.0087 0.0087
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0075 0.2232
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0184
Treponema pallidum DNA ligase (lig) 0.0016 0.0066 0.7917
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0016 0.0066 0.2746
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0206 0.0235
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0047 0.0251 0.0288
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0184
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0386 0.2321 0.2665
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0033 0.0033
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0021 0.0092 0.116
Echinococcus multilocularis Niemann Pick C1 protein 0.0127 0.0737 0.0737
Brugia malayi Steroid receptor seven-up type 2 0.0008 0.0013 0.0012
Echinococcus granulosus tachykinin peptides receptor 99D 0.0312 0.1866 0.1866
Schistosoma mansoni cellular tumor antigen P53 0.0044 0.0237 0.0235
Echinococcus multilocularis calpain 5 0.002 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Onchocerca volvulus 0.0014 0.0051 0.1109
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0012 0.0036 0.0621
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0078 0.1518
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0014 0.0051 0.0049
Brugia malayi hypothetical protein 0.0025 0.0117 0.0132
Schistosoma mansoni peptidylglycine monooxygenase 0.0037 0.0194 0.0192
Brugia malayi topoisomerase 0.0016 0.0066 0.0073
Plasmodium falciparum glutathione reductase 0.0024 0.0112 0.7672
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0517 0.3119 0.3119
Schistosoma mansoni nuclear hormone receptor 0.0008 0.0013 0.0011
Trichomonas vaginalis mercuric reductase, putative 0.0008 0.0016 0.0618
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0012 0.0036 0.1048
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0061 0.0337 1
Entamoeba histolytica protein kinase, putative 0.0014 0.005 0.0961
Echinococcus multilocularis g-protein coupled receptor 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0089 0.0505 1
Echinococcus granulosus sex peptide receptor 0.0014 0.0051 0.0051
Echinococcus multilocularis nibrin 0.0016 0.0066 0.0066
Echinococcus multilocularis microtubule associated protein 2 0.1645 1 1
Schistosoma mansoni rotamase 0.0021 0.0095 0.0093
Schistosoma mansoni Mername-AA248 (C02 family) 0.002 0.0087 0.0085
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0006 0.0005 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0051 0.0051
Brugia malayi B-box zinc finger family protein 0.0038 0.0195 0.0221
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.1096
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0066 0.2746
Onchocerca volvulus 0.0064 0.0354 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0145 0.0167
Echinococcus granulosus calpain 5 0.002 0.0087 0.0087
Echinococcus granulosus neuropeptide receptor 0.0014 0.0051 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0012 0.0036 0.0039
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0014 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Trypanosoma brucei calpain-like protein, putative 0.002 0.0087 0.2607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0008 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0197 0.0227
Echinococcus multilocularis expressed conserved protein 0.0083 0.0473 0.0473
Echinococcus granulosus Niemann Pick C1 protein 0.0127 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni ap endonuclease 0.0019 0.0078 0.0076
Schistosoma mansoni neuropeptide receptor 0.0014 0.0051 0.0049
Entamoeba histolytica acyl-CoA synthetase, putative 0.0039 0.0206 0.4056
Echinococcus multilocularis calpain family protein 1, d 0.0039 0.0202 0.0202
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0014 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0064 0.0354 0.0352
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Echinococcus multilocularis dnaJ subfamily B 0.026 0.1549 0.1549
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0008 0.0013 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0008 0.0013 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Trypanosoma brucei trypanothione reductase 0.0024 0.0112 0.3379
Schistosoma mansoni calpain (C02 family) 0.002 0.0087 0.0085
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0038 0.0197 0.0227
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0008 0.0013 0.0011
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0014 0.0051 0.0051
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0021 0.0092 0.2759
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0059 0.0328 1
Leishmania major kinesin, putative 0.0014 0.005 0.1487
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0012 0.0036 0.105
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0078 0.2347
Schistosoma mansoni biogenic amine (5HT) receptor 0.0014 0.0051 0.0049
Schistosoma mansoni acetyl-CoA synthetase 0.0012 0.0036 0.0034
Echinococcus granulosus orexin receptor type 2 0.0014 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0008 0.0013 0.0012
Brugia malayi DKFZp564C0469 protein 0.0016 0.0066 0.0073
Loa Loa (eye worm) hypothetical protein 0.0133 0.0776 0.0892
Brugia malayi steroid hormone receptor 0.0008 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0014 0.0051 0.0049
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0016 0.0066 0.259
Echinococcus multilocularis cpg binding protein 0.0019 0.0083 0.0083
Echinococcus multilocularis tripartite motif containing protein 3 0.0037 0.0194 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0197 0.8448
Brugia malayi ecdysteroid receptor 0.0008 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0095 0.4018
Plasmodium falciparum acyl-CoA synthetase 0.0029 0.0145 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus granulosus G protein coupled receptor 139 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0039 0.0206 0.0237
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0014 0.0051 0.0049
Echinococcus granulosus serotonin receptor 0.0014 0.0051 0.0051
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0029 0.0145 1
Loa Loa (eye worm) cathepsin B 0.0044 0.0233 0.0268
Echinococcus multilocularis tumor protein p63 0.0304 0.1818 0.1818
Brugia malayi Dopamine receptor protein 2 0.0014 0.0051 0.0056
Echinococcus granulosus expressed protein 0.0021 0.0095 0.0095
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0012 0.0036 0.0621
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0008 0.0013 0.0015
Loa Loa (eye worm) B-box zinc finger family protein 0.0038 0.0195 0.0224
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.1096
Trypanosoma brucei kinesin, putative 0.0014 0.005 0.1487
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0184
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0051 0.0051
Brugia malayi ORL1-like opioid receptor 0.0014 0.0051 0.0056
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi G protein-coupled receptor F59B2.13 0.0014 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Echinococcus granulosus cpg binding protein 0.0019 0.0083 0.0083
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0117 0.4969
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0016 0.0066 0.2747
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0066 0.2746
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0012 0.0036 0.0621
Toxoplasma gondii NADPH-glutathione reductase 0.0008 0.0016 0.0618
Echinococcus multilocularis serotonin receptor 0.0014 0.0051 0.0051
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0016 0.0066 0.1261
Schistosoma mansoni cpg binding protein 0.0018 0.0077 0.0075
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0206 0.0235
Schistosoma mansoni dopamine-beta-monooxygenase 0.0761 0.4606 0.4605
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0012 0.0036 0.1048
Brugia malayi G protein-coupled receptor 0.0014 0.0051 0.0056
Echinococcus multilocularis neuropeptide FF receptor 2 0.0014 0.0051 0.0051
Schistosoma mansoni biogenic amine (5HT) receptor 0.0014 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0013 0.0013
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0012 0.0036 0.1048
Brugia malayi Muscleblind-like protein 0.0242 0.144 0.1653
Echinococcus granulosus g protein coupled receptor 0.0014 0.0051 0.0051
Schistosoma mansoni brat protein 0.0037 0.0194 0.0192
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Echinococcus multilocularis protein patched 0.0038 0.0197 0.0197
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0014 0.0051 0.0049
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.2607
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0051 0.0051
Onchocerca volvulus 0.0014 0.0051 0.1109
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0013 0.0011
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0012 0.0036 0.1479
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0206 0.5924
Trichomonas vaginalis antibiotic synthetase, putative 0.0012 0.0036 0.1479
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0051 0.0051
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0018 0.0075 0.3075
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0008 0.0013 0.0013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0032 0.0158 0.0158
Brugia malayi calpain family protein 1 0.0053 0.0287 0.0328
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0053 0.0287 0.0285
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Onchocerca volvulus 0.0014 0.0051 0.1109
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0078 1
Entamoeba histolytica hypothetical protein 0.0016 0.0066 0.1261
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0008 0.0016 0.0438
Schistosoma mansoni histamine h1 receptor 0.0014 0.0051 0.0049
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0012 0.0036 0.2384
Chlamydia trachomatis DNA ligase 0.0016 0.0066 0.3811
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0008 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0014 0.0051 0.0058
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0051 0.0051
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0051 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Schistosoma mansoni cpg binding protein 0.0019 0.0083 0.0081
Loa Loa (eye worm) glutathione reductase 0.0024 0.0112 0.0129
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0018 0.0075 0.4524
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0145 0.0167
Brugia malayi neuropeptide F receptor 0.0014 0.0051 0.0056
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0018 0.0075 0.1821
Brugia malayi Serotonin receptor 0.0014 0.0051 0.0056
Schistosoma mansoni hypothetical protein 0.0037 0.0189 0.0187
Brugia malayi G-protein coupled receptor 0.0014 0.0051 0.0056
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0018 0.0075 0.9493
Leishmania major 4-coumarate:coa ligase-like protein 0.0039 0.0206 0.6273
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0087 0.1096
Loa Loa (eye worm) melatonin receptor type 1A 0.0014 0.0051 0.0058
Echinococcus granulosus transcription factor Dp 1 0.0034 0.0175 0.0175
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0051 0.0051
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0012 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0037 0.0189 0.0187
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0008 0.0013 0.0013
Loa Loa (eye worm) NCL-1 protein 0.0037 0.0194 0.0223
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0033 0.0033
Onchocerca volvulus 0.0014 0.0051 0.1109
Loa Loa (eye worm) hypothetical protein 0.0242 0.144 0.1655
Onchocerca volvulus 0.0014 0.0051 0.1109
Brugia malayi AKH receptor 0.0014 0.0051 0.0056
Echinococcus multilocularis expressed protein 0.0021 0.0095 0.0095
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0016 0.0066 0.8241
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0032 0.0158 0.0179
Onchocerca volvulus 0.0014 0.0051 0.1109
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0018 0.0075 0.4524
Schistosoma mansoni hypothetical protein 0.0037 0.0194 0.0192
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0013 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0112 0.142
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni hypothetical protein 0.0037 0.0194 0.0192
Brugia malayi calpain 7 0.002 0.0087 0.0098
Onchocerca volvulus 0.0014 0.0051 0.1109
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0078 1
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0016 0.0066 0.0974
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0012 0.0036 0.0621
Brugia malayi follicle stimulating hormone receptor 0.0014 0.0051 0.0056
Echinococcus multilocularis neuropeptide s receptor 0.0014 0.0051 0.0051
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0438
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0006 0.0005 0.0123
Mycobacterium leprae conserved hypothetical protein 0.0018 0.0075 0.128
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi Niemann-Pick C1 protein precursor 0.0089 0.0505 0.0578
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0021 0.0095 0.0107
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0014 0.0051 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0055 0.03 0.8837
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0078 0.2866
Trypanosoma brucei calpain-like protein, putative 0.002 0.0087 0.2607
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0006 0.0005 0.0037
Echinococcus granulosus calpain 0.002 0.0087 0.0087
Echinococcus multilocularis thioredoxin glutathione reductase 0.0024 0.0114 0.0114
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi calpain family protein 1 0.0053 0.0287 0.0328
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0133 0.0776 0.0774
Brugia malayi RE15519p 0.0014 0.0051 0.0056
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0117 0.8009
Echinococcus multilocularis protein dispatched 1 0.0043 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0039 0.0202 0.0233
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0008 0.0013 0.0011
Echinococcus multilocularis calpain 7 (C02 family) 0.002 0.0087 0.0087
Echinococcus multilocularis serotonin receptor 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0051 0.0051
Echinococcus multilocularis orexin receptor type 2 0.0014 0.0051 0.0051
Leishmania major 4-coumarate:coa ligase-like protein 0.0039 0.0206 0.6273
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0133 0.0776 0.0774
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0083 0.0472 0.0472
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0059 0.0328 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0012 0.0036 0.0441
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0036 0.0039
Onchocerca volvulus 0.0014 0.0051 0.1109
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0006 0.0005 0.0087
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Echinococcus granulosus tumor protein p63 0.0304 0.1818 0.1818
Plasmodium vivax replication factor C subunit 1, putative 0.0016 0.0066 0.3811
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0075
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0012 0.0036 0.0621
Onchocerca volvulus 0.0018 0.0077 0.1878
Schistosoma mansoni hypothetical protein 0.0037 0.0189 0.0187
Brugia malayi B-box zinc finger family protein 0.0037 0.0194 0.0221
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0016 0.0066 0.0073
Loa Loa (eye worm) oxidoreductase 0.0012 0.0036 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0036 0.0042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0008 0.0013 0.0013
Plasmodium falciparum thioredoxin reductase 0.0008 0.0016 0.0995
Loa Loa (eye worm) hypothetical protein 0.0053 0.0287 0.033
Entamoeba histolytica hypothetical protein 0.0037 0.0194 0.3812
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0051 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0051 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0032 0.0158 0.0181
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0296 0.1774 0.1772
Echinococcus granulosus replication factor c subunit 1 0.0016 0.0066 0.0066
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0037 0.0194 0.5895
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0037 0.0189 0.0187
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0014 0.0051 0.0051
Echinococcus granulosus thioredoxin glutathione reductase 0.0024 0.0114 0.0114
Brugia malayi CXXC zinc finger family protein 0.0018 0.0077 0.0086
Trichomonas vaginalis rotamase, putative 0.0021 0.0095 0.4018
Brugia malayi AMP-binding enzyme family protein 0.0012 0.0036 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0145 0.0167
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0051 0.0051
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0008 0.0016 0.0438
Echinococcus multilocularis calpain A 0.0055 0.0302 0.0302
Loa Loa (eye worm) thioredoxin reductase 0.0024 0.0112 0.0129
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus granulosus L aminoadipate semialdehyde 0.0064 0.0354 0.0354
Mycobacterium ulcerans hypothetical protein 0.0039 0.0206 1
Brugia malayi Dopamine receptor 0.0014 0.0051 0.0056
Onchocerca volvulus 0.0014 0.0051 0.1109
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0008 0.0013 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0184
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Plasmodium vivax thioredoxin reductase, putative 0.0024 0.0112 0.7415
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus multilocularis sex peptide receptor 0.0014 0.0051 0.0051
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0008 0.0016 0.0438
Schistosoma mansoni steroid hormone receptor ad4bp 0.0008 0.0013 0.0011
Schistosoma mansoni neuropeptide receptor 0.0014 0.0051 0.0049
Echinococcus multilocularis brain tumor protein 0.0037 0.0194 0.0194
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0014 0.0051 0.0049
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0014 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.0039 0.0206 0.0237
Schistosoma mansoni ap endonuclease 0.0019 0.0078 0.0076
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0014 0.0051 0.0051
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0087 0.1096
Brugia malayi AMP-binding enzyme family protein 0.0012 0.0036 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0008 0.0016 0.0438
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0133 0.0776 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0013 0.0012
Mycobacterium tuberculosis Probable reductase 0.0055 0.03 0.8837
Echinococcus granulosus 7TM GPCR rhodopsin 0.0014 0.0051 0.0051
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0014 0.0051 0.0049
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0018 0.0075 0.5069
Echinococcus granulosus ecdysone induced protein 78C 0.0008 0.0013 0.0013
Echinococcus granulosus calpain A 0.002 0.0087 0.0087
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0044 0.0233 0.2984
Echinococcus granulosus 7tm_1 domain containing protein 0.0014 0.0051 0.0051
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0051 0.0051
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0078 0.533
Onchocerca volvulus 0.0033 0.0166 0.4493
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0016 0.0066 0.195
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Entamoeba histolytica calpain large subunit domain III containing protein 0.0014 0.005 0.0961
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni growth hormone secretagogue receptor 0.0014 0.0051 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0032 0.0158 0.0158
Brugia malayi glutathione reductase 0.0024 0.0112 0.0126
Toxoplasma gondii peptidylprolyl isomerase 0.0021 0.0092 0.3886
Echinococcus granulosus neuropeptide receptor 0.0014 0.0051 0.0051
Entamoeba histolytica acyl-CoA synthetase, putative 0.0039 0.0206 0.4056
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0012 0.0036 0.1048
Toxoplasma gondii cathepsin B 0.0044 0.0233 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0206 1
Schistosoma mansoni calpain-7 (C02 family) 0.002 0.0087 0.0085
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0014 0.0051 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0008 0.0013 0.0013
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0145 0.6796
Brugia malayi Tachykinin-like peptides receptor 99D 0.0014 0.0051 0.0056
Brugia malayi G-protein coupled receptor 0.0014 0.0051 0.0056
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0051 0.0051
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0008 0.0016 0.0438
Onchocerca volvulus Neuropeptide F receptor homolog 0.0014 0.0051 0.1109
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0051 0.0049
Onchocerca volvulus 0.0039 0.0206 0.5676
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0039 0.0206 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0035 0.0176 0.7538
Onchocerca volvulus 0.0014 0.0051 0.1109
Echinococcus multilocularis Niemann Pick C1 protein 0.0089 0.0505 0.0505
Brugia malayi Melatonin receptor type 1A 0.0014 0.0051 0.0056
Brugia malayi B-box type zinc-finger protein ncl-1 0.0037 0.0194 0.0221
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0136 0.372
Loa Loa (eye worm) TYRA-2 protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0051 0.0058
Onchocerca volvulus 0.0014 0.0051 0.1109
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0018 0.0075 0.3145
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Brugia malayi hypothetical protein 0.0016 0.0066 0.0073
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0055 0.0302 0.0302
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0032 0.0158 0.0158
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0012 0.0036 0.0621
Loa Loa (eye worm) hypothetical protein 0.0064 0.0354 0.0406
Loa Loa (eye worm) hypothetical protein 0.0761 0.4606 0.5293
Echinococcus multilocularis ecdysone induced protein 78C 0.0008 0.0013 0.0013
Leishmania major phosphopantetheinyl transferase-like protein 0.0018 0.0075 0.2232
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0014 0.0051 0.0058
Echinococcus granulosus sterol regulatory element binding protein 0.0038 0.0197 0.0197
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0051 0.0051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0008 0.0016 0.0184
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0008 0.0013 0.0012
Echinococcus granulosus somatostatin receptor 0.0014 0.0051 0.0051
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0087 0.1096
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0008 0.0016 0.0438
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0032 0.0158 0.0158
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.1433 0.8703 0.8703
Echinococcus multilocularis muscleblind protein 1 0.0242 0.144 0.144
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0083 0.0472 0.0472
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.002 0.0087 0.1096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0133 0.0776 0.0774
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.002 0.0087 0.1096
Echinococcus granulosus Niemann Pick C1 protein 0.0089 0.0505 0.0505
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0117 0.1483
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0078 0.009
Leishmania major hypothetical protein, conserved 0.0025 0.0117 0.3527
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0075
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0078 0.0088
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0013 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0055 0.03 0.8837
Onchocerca volvulus 0.0014 0.0051 0.1109
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0055 0.0302 0.0302
Schistosoma mansoni opsin-like receptor 0.0014 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0014 0.0051 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0051 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0008 0.0016 0.0618
Brugia malayi sulfakinin receptor protein 0.0014 0.0051 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0012 0.0036 0.1048
Echinococcus granulosus tripartite motif containing protein 3 0.0037 0.0194 0.0194
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0006 0.0005 0.0037
Entamoeba histolytica hypothetical protein 0.0083 0.0472 0.9335
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0051 0.0051
Leishmania major acetyl-CoA synthetase, putative 0.0012 0.0036 0.105
Brugia malayi hypothetical protein 0.0014 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0012 0.0036 0.0042
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0039 0.0206 0.5654
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0012 0.0036 0.0621
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0014 0.0051 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0008 0.0013 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0078 0.3307
Loa Loa (eye worm) hypothetical protein 0.0014 0.0051 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0206 0.0235
Mycobacterium ulcerans acetyl-CoA synthetase 0.0012 0.0036 0.1048
Loa Loa (eye worm) hypothetical protein 0.0047 0.0249 0.0287
Onchocerca volvulus 0.0044 0.0237 0.6572
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0014 0.0051 0.0051
Onchocerca volvulus 0.0012 0.0036 0.0689
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0008 0.0013 0.0011
Toxoplasma gondii ATPase, AAA family protein 0.0016 0.0066 0.2747
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0012 0.0036 0.0042
Entamoeba histolytica hypothetical protein 0.0083 0.0472 0.9335
Echinococcus granulosus expressed conserved protein 0.0083 0.0473 0.0473
Giardia lamblia Hypothetical protein 0.0037 0.0194 0.8193
Schistosoma mansoni neuropeptide receptor 0.0014 0.0051 0.0049
Schistosoma mansoni calpain C (C02 family) 0.002 0.0087 0.0085
Echinococcus multilocularis brain tumor protein 0.0037 0.0194 0.0194
Echinococcus granulosus fmrfamide receptor 0.0014 0.0051 0.0051
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0051 0.0051
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0012 0.0036 0.105
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0016 0.0066 0.2746
Trichomonas vaginalis antibiotic synthetase, putative 0.0012 0.0036 0.1479
Schistosoma mansoni peptidyl-glycine monooxygenase 0.1433 0.8703 0.8703
Trypanosoma cruzi kinesin, putative 0.0014 0.005 0.0625
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0018 0.0075 0.3075
Echinococcus granulosus calpain A 0.0055 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0025 0.0117 0.0134
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0014 0.0051 0.0049
Schistosoma mansoni adenoreceptor 0.0014 0.0051 0.0049
Onchocerca volvulus 0.0014 0.0051 0.1109
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0194 0.0223
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0032 0.0158 0.0156
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0051 0.0051
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0012 0.0036 0.1048
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0012 0.0036 0.0679
Schistosoma mansoni RAR-like nuclear receptor 0.0008 0.0013 0.0011
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.002 0.0087 0.2607
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0051 0.0058
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0061 0.0337 1

Activities

Activity type Activity value Assay description Source Reference
RIC50 (binding) = 0.52 Inhibitory potency against sarco- endoplasmic reticulum calcium-ATPase in relative to thapsigargin ChEMBL. 15828839

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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