Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.0331 | 0.0316 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.0385 | 0.8469 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0086 | 0.0449 | 0.0435 |
Schistosoma mansoni | lamin | 0.0031 | 0.0071 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.0599 | 0.0585 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.0385 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0788 | 0.5251 | 0.5244 |
Echinococcus granulosus | lamin | 0.0031 | 0.0071 | 0.0056 |
Loa Loa (eye worm) | histone deacetylase | 0.0044 | 0.0161 | 0.0161 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.0331 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0192 | 0.1171 | 0.1158 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0086 | 0.0449 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1016 | 0.1016 |
Brugia malayi | Bromodomain containing protein | 0.0086 | 0.045 | 0.0421 |
Leishmania major | histone deacetylase, putative | 0.0044 | 0.0161 | 0.3684 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0071 | 0.0056 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0164 | 0.098 | 0.098 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0221 | 0.0192 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0474 | 0.3101 | 0.3091 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0071 | 0.0071 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0057 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0385 | 0.0385 |
Onchocerca volvulus | Slit protein homolog | 0.0164 | 0.098 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0071 | 0.0071 |
Brugia malayi | follicle stimulating hormone receptor | 0.1482 | 0.9994 | 0.9994 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0077 | 0.0385 | 0.4584 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.0385 | 0.0356 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0068 | 0.033 | 0.0315 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0849 | 0.0835 |
Echinococcus multilocularis | insulin receptor | 0.0474 | 0.3101 | 0.3091 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0529 | 0.348 | 0.347 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.0928 | 0.0915 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0077 | 0.0385 | 0.0371 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0221 | 0.0221 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0917 | 0.6129 | 0.6123 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.0162 | 0.0132 |
Echinococcus granulosus | epidermal growth factor receptor | 0.1483 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0797 | 0.5309 | 0.5302 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.0331 | 0.0901 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0385 | 0.0385 |
Leishmania major | histone deacetylase, putative | 0.0044 | 0.0161 | 0.3684 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0181 | 0.0181 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0156 | 0.0928 | 0.0915 |
Plasmodium vivax | histone deacetylase, putative | 0.0044 | 0.0161 | 0.312 |
Schistosoma mansoni | tyrosine kinase | 0.0797 | 0.5309 | 0.5302 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0385 | 0.0385 |
Trypanosoma brucei | histone deacetylase, putative | 0.0044 | 0.0161 | 0.3684 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0044 | 0.0161 | 0.0392 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0797 | 0.5309 | 0.5302 |
Mycobacterium ulcerans | lipase LipD | 0.0077 | 0.0385 | 0.4584 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0077 | 0.0385 | 0.0467 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0518 | 0.3406 | 0.3396 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0077 | 0.0385 | 0.0467 |
Echinococcus multilocularis | geminin | 0.0192 | 0.1171 | 0.1158 |
Echinococcus granulosus | slit 2 protein | 0.0164 | 0.098 | 0.0967 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.0385 | 0.0371 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0044 | 0.0161 | 0.0146 |
Schistosoma mansoni | tyrosine kinase | 0.0788 | 0.5251 | 0.5244 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0518 | 0.3406 | 0.3396 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0193 | 0.0178 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0144 | 0.0849 | 0.0835 |
Toxoplasma gondii | ABC1 family protein | 0.0077 | 0.0385 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0196 | 0.0196 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0038 | 0.0023 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.003 | 0.0064 | 0.0803 |
Brugia malayi | Protein kinase domain containing protein | 0.0474 | 0.3101 | 0.308 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0474 | 0.3101 | 0.3091 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.0331 | 0.0316 |
Schistosoma mansoni | tyrosine kinase | 0.0797 | 0.5309 | 0.5302 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0416 | 0.0416 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0156 | 0.0928 | 0.0915 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.0385 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.0044 | 0.0161 | 0.0146 |
Echinococcus granulosus | muscleblind protein | 0.0169 | 0.1016 | 0.1003 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0071 | 0.0056 |
Trichomonas vaginalis | esterase, putative | 0.0077 | 0.0385 | 0.5 |
Onchocerca volvulus | 0.0108 | 0.0599 | 0.5809 | |
Echinococcus multilocularis | lamin | 0.0031 | 0.0071 | 0.0056 |
Echinococcus granulosus | histone deacetylase 6 | 0.0044 | 0.0161 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0193 | 0.0193 |
Plasmodium falciparum | histone deacetylase, putative | 0.0044 | 0.0161 | 0.312 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1016 | 0.1016 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0044 | 0.0161 | 0.0146 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0077 | 0.0385 | 0.0371 |
Brugia malayi | Histone deacetylase family protein | 0.0044 | 0.0161 | 0.0131 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0797 | 0.5309 | 0.5302 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0385 | 0.0385 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0162 | 0.0162 |
Brugia malayi | hypothetical protein | 0.0529 | 0.348 | 0.346 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0086 | 0.0449 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0068 | 0.0068 |
Trypanosoma brucei | histone deacetylase 3 | 0.0044 | 0.0161 | 0.3684 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0071 | 0.0056 |
Brugia malayi | Probable ClpP-like protease | 0.0086 | 0.0449 | 0.042 |
Echinococcus granulosus | histone deacetylase 6 | 0.0044 | 0.0161 | 0.0146 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.0385 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0161 | 0.0161 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.0385 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0331 | 0.0316 |
Schistosoma mansoni | bromodomain containing protein | 0.0073 | 0.0358 | 0.0343 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0792 | 0.5274 | 0.5267 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0077 | 0.0385 | 0.0467 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 0.5 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0064 | 0.0803 |
Onchocerca volvulus | 0.0077 | 0.0385 | 0.3451 | |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0077 | 0.0385 | 0.4584 |
Brugia malayi | Muscleblind-like protein | 0.0169 | 0.1016 | 0.0989 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0044 | 0.0161 | 0.0146 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0144 | 0.0849 | 0.0835 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0044 | 0.0161 | 0.3684 |
Onchocerca volvulus | 0.0077 | 0.0385 | 0.3451 | |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.0247 | 0.0232 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.0385 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0056 | 0.0247 | 0.4744 |
Onchocerca volvulus | 0.0048 | 0.0193 | 0.1336 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0107 | 0.0107 |
Mycobacterium leprae | conserved hypothetical protein | 0.0077 | 0.0385 | 0.8335 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0529 | 0.348 | 0.347 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0449 | 0.0449 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.0385 | 0.0467 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0164 | 0.098 | 0.0953 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.0385 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0489 | 0.3207 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0161 | 0.0161 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0044 | 0.0161 | 0.0146 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0071 | 0.0041 |
Echinococcus multilocularis | 0.0459 | 0.3 | 0.2989 | |
Trypanosoma cruzi | histone deacetylase, putative | 0.0044 | 0.0161 | 0.3684 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0792 | 0.5274 | 0.5267 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.0385 | 0.0467 |
Echinococcus granulosus | histone deacetylase | 0.0044 | 0.0161 | 0.0146 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0038 | 0.0023 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0044 | 0.0161 | 0.312 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0068 | 0.033 | 0.0315 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0143 | 0.0128 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.1483 | 1 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 0.0435 |
Echinococcus granulosus | neuropeptide s receptor | 0.0518 | 0.3406 | 0.3396 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0071 | 0.0056 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.1483 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0331 | 0.0316 |
Schistosoma mansoni | tyrosine kinase | 0.1483 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0069 | 0.0331 | 0.8469 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.1482 | 0.9994 | 0.9994 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0077 | 0.0385 | 0.0467 |
Echinococcus multilocularis | tumor protein p63 | 0.0331 | 0.2125 | 0.2113 |
Echinococcus multilocularis | muscleblind protein | 0.0169 | 0.1016 | 0.1003 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0518 | 0.3406 | 0.3396 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.0247 | 0.0232 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0077 | 0.0385 | 0.4584 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0077 | 0.0385 | 0.0467 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0044 | 0.0161 | 0.0146 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.0385 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0529 | 0.348 | 0.348 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0221 | 0.0192 |
Trypanosoma brucei | histone deacetylase 4 | 0.0044 | 0.0161 | 0.3684 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0023 | 0.0008 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.0385 | 0.0371 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0107 | 0.0093 |
Schistosoma mansoni | tyrosine kinase | 0.0788 | 0.5251 | 0.5244 |
Echinococcus multilocularis | slit 2 protein | 0.0164 | 0.098 | 0.0967 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0044 | 0.0161 | 0.0146 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0077 | 0.0385 | 0.0385 |
Echinococcus multilocularis | histone deacetylase | 0.0044 | 0.0161 | 0.0146 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0143 | 0.0128 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0044 | 0.0161 | 0.0146 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0107 | 0.0077 |
Onchocerca volvulus | 0.0164 | 0.098 | 0.9992 | |
Brugia malayi | beta-lactamase | 0.0077 | 0.0385 | 0.0356 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0792 | 0.5274 | 0.5267 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0474 | 0.3101 | 0.3101 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.0385 | 0.5 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0108 | 0.0599 | 0.0571 |
Schistosoma mansoni | tyrosine kinase | 0.0474 | 0.3101 | 0.3091 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0071 | 0.0071 |
Brugia malayi | Histone deacetylase family protein | 0.0044 | 0.0161 | 0.0131 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0077 | 0.0385 | 0.0356 |
Schistosoma mansoni | hypothetical protein | 0.0192 | 0.1171 | 0.1158 |
Brugia malayi | EGF-like domain containing protein | 0.0164 | 0.098 | 0.0953 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.003 | 0.003 |
Plasmodium falciparum | histone deacetylase 2 | 0.0044 | 0.0161 | 0.312 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.0385 | 0.0467 |
Onchocerca volvulus | 0.0077 | 0.0385 | 0.3451 | |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0038 | 0.0023 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0044 | 0.0161 | 0.3684 |
Echinococcus granulosus | insulin receptor | 0.0474 | 0.3101 | 0.3091 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0071 | 0.0056 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0512 | 0.3364 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0077 | 0.0385 | 1 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 0.0435 |
Loa Loa (eye worm) | beta-lactamase | 0.0077 | 0.0385 | 0.0385 |
Schistosoma mansoni | tyrosine kinase | 0.0474 | 0.3101 | 0.3091 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0086 | 0.0449 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0077 | 0.0385 | 0.8335 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0077 | 0.0385 | 0.0467 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0023 | 0.0023 |
Schistosoma mansoni | lamin | 0.0031 | 0.0071 | 0.0056 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0.0064 | 0.0101 |
Schistosoma mansoni | survival motor neuron protein | 0.0108 | 0.0599 | 0.0585 |
Mycobacterium ulcerans | hypothetical protein | 0.0077 | 0.0385 | 0.4584 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.0449 | 0.5 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0077 | 0.0385 | 0.0467 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0044 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0385 | 0.0385 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0169 | 0.1016 | 0.1003 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0385 | 0.0385 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0086 | 0.0449 | 1 |
Echinococcus granulosus | geminin | 0.0192 | 0.1171 | 0.1158 |
Echinococcus granulosus | tumor protein p63 | 0.0331 | 0.2125 | 0.2113 |
Echinococcus granulosus | histone deacetylase 7 | 0.0044 | 0.0161 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.098 | 0.098 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0071 | 0.0041 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.0385 | 0.0356 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Concentration (functional) | = 0.06 ug ml-1 | Minimum fungicidal concentration of the compound against Candida tropicalis MY 1012 | ChEMBL. | 1732529 |
Concentration (functional) | = 0.125 ug ml-1 | Minimum fungicidal concentration of the compound against Candida albicans MY 1028 | ChEMBL. | 1732529 |
Concentration (functional) | = 0.25 ug ml-1 | Minimum fungicidal concentration of the compound against Candida albicans MY 1055 | ChEMBL. | 1732529 |
Concentration (functional) | = 2 ug ml-1 | Minimum fungicidal concentration of the compound against Candida pseudotropicalis MY 1100 | ChEMBL. | 1732529 |
Concentration (functional) | = 4 ug ml-1 | Minimum fungicidal concentration of the compound against Candida parapsilosis MY 1010 | ChEMBL. | 1732529 |
Concentration (functional) | > 400 ug ml-1 | Hemolytic potential was determined as the minimum lytic concentration of the compound against human red blood cells | ChEMBL. | 1732529 |
IC50 (functional) | = 0.07 uM | Inhibitory activity against glucan synthesis | ChEMBL. | 1732529 |
MED90 (functional) | = 0.15 MKP | Minimum effect dose required to reduce the number of alveolor cyst load in rat Pneumocystis carinii pneumonia assay | ChEMBL. | 1732529 |
MED99 (functional) | = 3 MKP | Minimum effect dose required to reduce the number of colony forming units in per gram kidney of mice after being challenged, by tail vein injection, with 5 X l0e4 cells of C. albicans (MY 1055) | ChEMBL. | 1732529 |
MED99 (functional) | = 3 MKP | Minimum effect dose required to reduce the number of colony forming units in per gram kidney of mice after being challenged, by tail vein injection, with 5 X l0e4 cells of C. albicans (MY 1055) | ChEMBL. | 1732529 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.