Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.0127 | 0.0165 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0104 | 0.0293 | 0.0378 |
Brugia malayi | Cathepsin L-like precursor | 0.0052 | 0.0078 | 0.0101 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0073 | 0.0094 |
Plasmodium vivax | unspecified product | 0.008 | 0.0195 | 0.361 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0052 | 0.0078 | 0.0101 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0723 | 0.2798 | 0.3595 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0156 | 0.0502 | 0.0502 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0156 | 0.0502 | 0.0502 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.0347 | 0.0448 |
Plasmodium vivax | plasmepsin IV, putative | 0.0154 | 0.0492 | 0.9793 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0021 | 0.0021 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0043 | 0.0043 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.0152 | 0.0196 |
Brugia malayi | Cathepsin L-like precursor | 0.0156 | 0.0502 | 0.0648 |
Onchocerca volvulus | Cathepsin F homolog | 0.0156 | 0.0502 | 0.1875 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0261 | 0.0337 |
Brugia malayi | Cathepsin L-like precursor | 0.0104 | 0.0293 | 0.0378 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Plasmodium vivax | aspartyl protease, putative | 0.0045 | 0.0051 | 0.0611 |
Entamoeba histolytica | cysteine protease, putative | 0.0156 | 0.0502 | 1 |
Plasmodium vivax | unspecified product | 0.0052 | 0.0078 | 0.1177 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0021 | 0.0021 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.008 | 0.0195 | 0.0195 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0156 | 0.0502 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0156 | 0.0502 | 0.0502 |
Echinococcus multilocularis | solute carrier family 5 | 0.25 | 1 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.25 | 1 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Plasmodium falciparum | plasmepsin X | 0.0124 | 0.0372 | 0.7304 |
Brugia malayi | Cathepsin L-like precursor | 0.0156 | 0.0502 | 0.0648 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0045 | 0.0051 | 0.0066 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0104 | 0.0293 | 0.3182 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0021 | 0.0021 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0156 | 0.0502 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.0283 | 0.0365 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.008 | 0.0195 | 0.0224 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.0195 | 0.0224 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0723 | 0.2798 | 0.3595 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.008 | 0.0195 | 0.0252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0101 | 0.0279 | 0.0279 |
Onchocerca volvulus | 0.0104 | 0.0293 | 0.1005 | |
Plasmodium vivax | aspartyl proteinase, putative | 0.0045 | 0.0051 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.2454 | 0.3168 |
Brugia malayi | Pepsin A precursor | 0.0045 | 0.0051 | 0.0066 |
Plasmodium vivax | aspartyl protease, putative | 0.0124 | 0.0372 | 0.7304 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | fibroinase | 0.0156 | 0.0502 | 0.0648 |
Onchocerca volvulus | Cathepsin L homolog | 0.0156 | 0.0502 | 0.1875 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.0347 | 0.0448 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0156 | 0.0502 | 1 |
Brugia malayi | Sodium:solute symporter family protein | 0.0638 | 0.2454 | 0.3168 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0021 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0104 | 0.0293 | 0.0293 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0154 | 0.0492 | 0.9793 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0073 | 0.0094 |
Leishmania major | cysteine peptidase A (CPA) | 0.0156 | 0.0502 | 0.0621 |
Brugia malayi | hypothetical protein | 0.0097 | 0.0261 | 0.0337 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0073 | 0.0073 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0156 | 0.0502 | 1 |
Toxoplasma gondii | aspartyl protease | 0.0045 | 0.0051 | 0.0038 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0261 | 0.0337 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.25 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.008 | 0.0195 | 0.0224 |
Brugia malayi | Cathepsin L-like precursor | 0.0156 | 0.0502 | 0.0648 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Plasmodium falciparum | plasmepsin IX | 0.0124 | 0.0372 | 0.7304 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0524 | 0.1991 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0051 | 0.0066 |
Plasmodium falciparum | plasmepsin I | 0.0154 | 0.0492 | 0.9793 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0156 | 0.0502 | 0.0502 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Schistosoma mansoni | high-affinity choline transporter | 0.0638 | 0.2454 | 0.2454 |
Schistosoma mansoni | cathepsin s | 0.0052 | 0.0078 | 0.0078 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0152 | 0.0196 |
Plasmodium vivax | plasmepsin V, putative | 0.0045 | 0.0051 | 0.0611 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0156 | 0.0502 | 0.0502 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.008 | 0.0195 | 0.0224 |
Echinococcus granulosus | cysteine protease | 0.008 | 0.0195 | 0.0195 |
Brugia malayi | jmjC domain containing protein | 0.0101 | 0.0279 | 0.036 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0052 | 0.0078 | 0.0101 |
Loa Loa (eye worm) | ctsf protein | 0.0156 | 0.0502 | 0.0648 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0104 | 0.0293 | 0.0351 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0073 | 0.0073 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0038 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.0283 | 0.0365 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0045 | 0.0051 | 0.0611 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0154 | 0.0492 | 0.0492 |
Onchocerca volvulus | 0.0638 | 0.2454 | 1 | |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0045 | 0.0051 | 0.0066 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0073 | 0.0073 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0723 | 0.2798 | 0.3595 |
Plasmodium vivax | aspartyl protease, putative | 0.0124 | 0.0372 | 0.7304 |
Plasmodium vivax | vivapain-2 | 0.0156 | 0.0502 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Schistosoma mansoni | sodium/solute symporter | 0.0638 | 0.2454 | 0.2454 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0152 | 0.0152 |
Plasmodium falciparum | plasmepsin VII | 0.0045 | 0.0051 | 0.0611 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0045 | 0.0051 | 0.0038 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0052 | 0.0078 | 0.0073 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.1944 | 0.7746 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.008 | 0.0195 | 0.361 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Plasmodium falciparum | plasmepsin VI | 0.0154 | 0.0492 | 0.9793 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0156 | 0.0502 | 0.0621 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.008 | 0.0195 | 0.0224 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0156 | 0.0502 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.0492 | 0.0635 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0073 | 0.0073 |
Plasmodium falciparum | plasmepsin IV | 0.0154 | 0.0492 | 0.9793 |
Loa Loa (eye worm) | hypothetical protein | 0.0638 | 0.2454 | 0.3168 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0021 | 0.0027 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0156 | 0.0502 | 0.0648 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Plasmodium vivax | vivapain-1 | 0.008 | 0.0195 | 0.361 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0052 | 0.0078 | 0.0101 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.008 | 0.0195 | 0.0224 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Echinococcus granulosus | cathepsin l1 | 0.0156 | 0.0502 | 0.0502 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0073 | 0.0073 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0638 | 0.2454 | 0.2454 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0104 | 0.0293 | 0.0293 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0154 | 0.0492 | 0.0492 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0638 | 0.2454 | 0.2454 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0084 | 0.0108 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0104 | 0.0293 | 0.3182 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0038 | 0.0022 | 0.0022 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0156 | 0.0502 | 0.0621 |
Plasmodium falciparum | plasmepsin III | 0.0045 | 0.0051 | 0.0611 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0156 | 0.0502 | 0.0648 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0723 | 0.2798 | 0.3595 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0038 | 0.0022 | 0.0028 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0156 | 0.0502 | 0.0621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Brugia malayi | Augmenter of liver regeneration | 0.0038 | 0.0022 | 0.0028 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0021 | 0.0021 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0124 | 0.0372 | 0.0454 |
Brugia malayi | Papain family cysteine protease containing protein | 0.008 | 0.0195 | 0.0252 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.1944 | 0.7746 | 0.7746 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Plasmodium falciparum | plasmepsin V | 0.0045 | 0.0051 | 0.0611 |
Echinococcus multilocularis | cysteine protease | 0.0156 | 0.0502 | 0.0502 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0723 | 0.2798 | 0.3595 |
Plasmodium falciparum | plasmepsin II | 0.0154 | 0.0492 | 0.9793 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.008 | 0.0195 | 0.0195 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.1944 | 0.7746 | 1 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.25 | 1 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Trypanosoma cruzi | cysteine protease, putative | 0.008 | 0.0195 | 0.0224 |
Echinococcus granulosus | cathepsin L | 0.008 | 0.0195 | 0.0195 |
Brugia malayi | cathepsin L-like precursor | 0.0104 | 0.0293 | 0.0378 |
Brugia malayi | Cathepsin L-like precursor | 0.0156 | 0.0502 | 0.0648 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0104 | 0.0293 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.1944 | 0.7746 | 0.7746 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0052 | 0.0078 | 0.0073 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0051 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0078 | 0.0101 |
Brugia malayi | Cathepsin L-like precursor | 0.0156 | 0.0502 | 0.0648 |
Brugia malayi | GH02984p | 0.0638 | 0.2454 | 0.3168 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0156 | 0.0502 | 0.1875 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0045 | 0.0051 | 0.0066 |
Toxoplasma gondii | cathepsin CPL | 0.0156 | 0.0502 | 0.0621 |
Schistosoma mansoni | jumonji domain containing protein | 0.008 | 0.0195 | 0.0195 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0156 | 0.0502 | 0.0502 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.0502 | 0.0648 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.1944 | 0.7746 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0156 | 0.0502 | 0.0648 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.1944 | 0.7746 | 1 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.1944 | 0.7746 | 1 |
Onchocerca volvulus | 0.0156 | 0.0502 | 0.1875 | |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0638 | 0.2454 | 0.2454 |
Schistosoma mansoni | inositol transporter | 0.25 | 1 | 1 |
Leishmania major | 0.1944 | 0.7746 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0045 | 0.0051 | 0.0066 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.25 | 1 | 1 |
Onchocerca volvulus | 0.0156 | 0.0502 | 0.1875 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0045 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0293 | 0.0378 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0502 | 0.0621 |
Onchocerca volvulus | 0.0156 | 0.0502 | 0.1875 | |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.1944 | 0.7746 | 0.7746 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0051 | 0.0066 |
Toxoplasma gondii | fructose-bisphospatase II | 0.1944 | 0.7746 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0293 | 0.0378 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0154 | 0.0492 | 0.0492 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0156 | 0.0502 | 0.0621 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.0283 | 0.0365 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0154 | 0.0492 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0051 | 0.0066 |
Onchocerca volvulus | 0.0156 | 0.0502 | 0.1875 | |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0154 | 0.0492 | 0.0635 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0045 | 0.0051 | 0.0066 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | cysteine protease | 0.0156 | 0.0502 | 0.0648 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0078 | 0.0101 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.008 | 0.0195 | 0.0195 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.0347 | 0.0448 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0524 | 0.1991 | 0.1991 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.25 | 1 | 1 |
Onchocerca volvulus | 0.0156 | 0.0502 | 0.1875 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0283 | 0.0365 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.008 | 0.0195 | 0.0195 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0154 | 0.0492 | 0.0609 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0638 | 0.2454 | 0.2454 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0156 | 0.0502 | 0.0502 |
Brugia malayi | Cathepsin L-like precursor | 0.0104 | 0.0293 | 0.0378 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0638 | 0.2454 | 0.3149 |
Echinococcus multilocularis | cysteine protease | 0.0156 | 0.0502 | 0.0502 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0043 | 0.0043 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0154 | 0.0492 | 0.9675 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0293 | 0.0378 |
Schistosoma mansoni | eyes absent homolog | 0.0097 | 0.0261 | 0.0261 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0156 | 0.0502 | 0.0502 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0502 | 0.0621 |
Plasmodium vivax | vivapain-2 | 0.0156 | 0.0502 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0156 | 0.0502 | 1 |
Onchocerca volvulus | 0.0156 | 0.0502 | 0.1875 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0156 | 0.0502 | 0.0621 |
Plasmodium vivax | vivapain-3 | 0.008 | 0.0195 | 0.361 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0101 | 0.0279 | 0.0279 |
Onchocerca volvulus | 0.0156 | 0.0502 | 0.1875 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0156 | 0.0502 | 0.0648 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0078 | 0.0101 |
Echinococcus multilocularis | cathepsin L | 0.008 | 0.0195 | 0.0195 |
Schistosoma mansoni | inositol transporter | 0.25 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC80 (functional) | = 6.25 ug ml-1 | Antifungal activity against Cryptococcus neoformans after 72 hrs | ChEMBL. | 16905318 |
MIC80 (functional) | = 6.25 ug ml-1 | Antifungal activity against Cryptococcus neoformans after 72 hrs | ChEMBL. | 16905318 |
MIC80 (functional) | = 12.5 ug ml-1 | Antifungal activity against Microsporum canis after 7 days | ChEMBL. | 16905318 |
MIC80 (functional) | = 25 ug ml-1 | Antifungal activity against Trichophyton rubrum after 7 days | ChEMBL. | 16905318 |
MIC80 (functional) | = 50 ug ml-1 | Antifungal activity against Candida parapsilosis after 24 hrs | ChEMBL. | 16905318 |
MIC80 (functional) | = 50 ug ml-1 | Antifungal activity against Candida albicans after 24 hrs | ChEMBL. | 16905318 |
MIC80 (functional) | = 50 ug ml-1 | Antifungal activity against Candida albicans after 24 hrs | ChEMBL. | 16905318 |
MIC80 (functional) | > 200 ug ml-1 | Antifungal activity against Aspergillus fumigatus after 7 days | ChEMBL. | 16905318 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.