Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Schistosoma mansoni | glutaminase | 0.0279 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.1172 | 0.1096 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.1172 | 0.1172 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0977 | 0.0977 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.1172 | 0.1116 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.1534 | 0.1534 |
Loa Loa (eye worm) | glutaminase | 0.0279 | 1 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.1172 | 0.1116 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.1172 | 0.1116 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0135 | 0.0135 |
Trichomonas vaginalis | glutaminase, putative | 0.0279 | 1 | 1 |
Trypanosoma cruzi | cyclic nucleotide phosphodiesterase | 0.0222 | 0.7927 | 1 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0143 | 0.0143 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.1172 | 0.75 |
Loa Loa (eye worm) | glutaminase 2 | 0.0279 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.3451 | 0.3451 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0228 | 0.0228 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0236 | 0.0236 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.002 | 0.0553 | 0.0333 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0222 | 0.7927 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0532 | 1 |
Leishmania major | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0532 | 0.0472 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0135 | 0.0346 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0147 | 0.0428 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0135 | 0.0346 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0135 | 0.0346 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0236 | 0.0174 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0977 | 0.6158 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0977 | 0.0977 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0011 | 0.0236 | 0.0236 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1534 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2306 | 0.2306 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.1172 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0135 | 0.0135 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.1172 | 0.0966 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.1172 | 0.1226 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1172 | 0.1172 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.1172 | 0.1116 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.1758 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0236 | 0.0236 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.1172 | 0.1226 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0135 | 0.0051 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0011 | 0.0236 | 0.0236 |
Echinococcus multilocularis | smad | 0.0008 | 0.0135 | 0.0346 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0235 | 0.8388 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.1172 | 0.0966 |
Onchocerca volvulus | 0.0037 | 0.1172 | 1 | |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.1172 | 0.0966 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0532 | 0.0451 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.1038 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.1172 | 0.1172 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trypanosoma cruzi | cytochrome P450, putative | 0.002 | 0.0553 | 0.0423 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0135 | 0.0346 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1534 | 0.1461 |
Leishmania major | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0907 | 0.0829 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1172 | 0.1172 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0977 | 0.6158 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0011 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0236 | 0.0236 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.1172 | 0.0966 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0532 | 0.0396 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0135 | 0.0135 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0236 | 0.0236 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.3451 | 0.3451 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.1172 | 0.6171 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.2306 | 0.2306 |
Leishmania major | hypothetical protein, conserved | 0.0222 | 0.7927 | 1 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1172 | 0.1172 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.1172 | 0.1172 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.1172 | 0.75 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trypanosoma brucei | cytochrome P450, putative | 0.002 | 0.0553 | 0.0423 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0011 | 0.0236 | 0.0236 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Brugia malayi | Smad1 | 0.0008 | 0.0135 | 0.0135 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.1172 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.002 | 0.0553 | 0.0553 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0977 | 0.0977 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0977 | 0.0977 |
Brugia malayi | Cytochrome P450 family protein | 0.002 | 0.0553 | 0.0553 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0532 | 0.5 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0011 | 0.0236 | 0.1038 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Brugia malayi | beta-lactamase | 0.0037 | 0.1172 | 0.1172 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0977 | 0.09 |
Onchocerca volvulus | 0.0037 | 0.1172 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1534 | 0.1461 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0236 | 0.0236 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0977 | 0.6158 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0907 | 0.0829 |
Schistosoma mansoni | cytochrome P450 | 0.0011 | 0.0228 | 0.0144 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0532 | 0.0532 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0977 | 0.6158 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0937 | 0.0937 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0977 | 0.09 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0011 | 0.0236 | 0.001 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0228 | 0.0144 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0011 | 0.0236 | 0.0236 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.1172 | 0.1157 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.1172 | 0.0966 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0849 | 0.0849 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0977 | 0.09 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.1172 | 0.1157 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0977 | 0.6158 |
Leishmania major | cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 | 0.0011 | 0.0236 | 0.001 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0532 | 0.0472 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0135 | 0.0051 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0135 | 0.0051 |
Schistosoma mansoni | smad | 0.0008 | 0.0135 | 0.0051 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0135 | 0.0135 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0532 | 1 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0135 | 0.0051 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0937 | 0.0937 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1172 | 0.1172 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1534 | 1 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Echinococcus multilocularis | high affinity cgmp specific 3' 5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0532 | 0.0396 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.1172 | 0.1172 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.1988 | 0.1919 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0135 | 0.0135 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.2306 | 0.224 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.4273 | 0.4273 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.1172 | 0.1157 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.1172 | 0.1172 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1534 | 1 |
Echinococcus granulosus | high affinity cgmp specific 3' 5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0135 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0159 | 0.0159 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.1038 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.1534 | 0.1534 |
Schistosoma mansoni | camp-specific cyclic nucleotide phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Mycobacterium ulcerans | glutaminase | 0.0279 | 1 | 1 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0011 | 0.0236 | 0.001 |
Echinococcus granulosus | smad | 0.0008 | 0.0135 | 0.0346 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0135 | 0.0135 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0532 | 0.0396 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.1172 | 0.1226 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0532 | 0.5 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0011 | 0.0236 | 0.1038 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.1172 | 0.1157 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.1172 | 0.1157 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0532 | 0.0451 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0135 | 0.0346 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0532 | 0.5 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0532 | 0.0396 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0977 | 0.09 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0532 | 0.3086 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0011 | 0.0228 | 0.0983 |
Trypanosoma cruzi | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.1172 | 0.1157 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.1172 | 0.1116 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0147 | 0.0428 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Leishmania major | cytochrome p450-like protein | 0.002 | 0.0553 | 0.0423 |
Onchocerca volvulus | 0.0037 | 0.1172 | 1 | |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | cytochrome P450 | 0.0011 | 0.0228 | 0.0228 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.1172 | 0.1157 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.1172 | 0.1157 |
Trypanosoma cruzi | cytochrome P450, putative | 0.002 | 0.0553 | 0.0423 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.1038 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1534 | 0.1461 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1172 | 0.1172 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0532 | 0.0532 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0236 | 0.0236 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0849 | 0.077 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0849 | 0.0849 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1172 | 0.1172 |
Echinococcus multilocularis | 0.0011 | 0.0228 | 0.0983 | |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0977 | 0.6158 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Brugia malayi | cytochrome P450 | 0.0011 | 0.0228 | 0.0228 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0011 | 0.0236 | 0.001 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.1172 | 0.1157 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0532 | 0.0373 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.4273 | 0.4273 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0532 | 0.3086 |
Loa Loa (eye worm) | PDE1B protein | 0.0011 | 0.0236 | 0.0236 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0236 | 0.0174 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.1172 | 0.1096 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0553 | 0.0553 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0532 | 0.1991 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0532 | 0.0312 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0135 | 0.0051 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.1038 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.1172 | 0.1116 |
Trypanosoma cruzi | cAMP phosphodiesterase A, putative | 0.0011 | 0.0236 | 0.001 |
Trypanosoma brucei | cAMP phosphodiesterase A, putative | 0.0011 | 0.0236 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.3451 | 0.3451 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0532 | 0.3169 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1534 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0907 | 0.567 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.3451 | 0.3451 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0907 | 0.567 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.1172 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0553 | 0.0553 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.1172 | 0.1226 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0011 | 0.0236 | 0.0174 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.4273 | 0.4273 |
Loa Loa (eye worm) | CYP4Cod1 | 0.002 | 0.0553 | 0.0553 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0236 | 0.001 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0011 | 0.0236 | 0.0152 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0011 | 0.0236 | 0.1038 |
Trypanosoma brucei | cAMP-specific phosphodiesterase, putative | 0.0011 | 0.0236 | 0.001 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.1172 | 0.1157 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0135 | 0.0346 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0011 | 0.0236 | 0.0052 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.