Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Cavia porcellus | Platelet activating factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | roundabout 2 | 0.0078 | 0.0056 | 0.0054 |
Schistosoma mansoni | cell adhesion molecule | 0.0138 | 0.0218 | 0.0218 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.009 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0063 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0016 | 0.0016 |
Brugia malayi | Variant SH3 domain containing protein | 0.0064 | 0.0019 | 0.0049 |
Onchocerca volvulus | 0.1193 | 0.3085 | 0.3083 | |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.0147 | 0.0145 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.009 | 0.0088 | 0.0086 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.0016 | 0.5 |
Plasmodium vivax | phosphoglycerate mutase, putative | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.009 | 0.0088 | 0.0086 |
Schistosoma mansoni | tyrosine kinase | 0.0058 | 0.0002 | 0.0002 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0064 | 0.0019 | 0.0019 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.0088 | 0.0088 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.008 | 0.0063 | 0.0061 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0063 | 0.0016 | 0.0014 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3739 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.009 | 0.0088 | 0.0086 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.009 | 0.0088 | 0.0086 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Schistosoma mansoni | nephrin | 0.0078 | 0.0056 | 0.0056 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0063 | 0.0016 | 0.5 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.3739 | 1 | 1 | |
Echinococcus multilocularis | c src tyrosine kinase | 0.009 | 0.0088 | 0.0086 |
Mycobacterium tuberculosis | Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | roundabout 2 | 0.0158 | 0.0274 | 0.0272 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3676 | 0.9829 | 0.9828 |
Schistosoma mansoni | tyrosine kinase | 0.0058 | 0.0002 | 0.0002 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0078 | 0.0056 | 0.0054 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0063 | 0.0016 | 0.0039 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1595 | 0.4178 | 0.4169 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3676 | 0.9829 | 0.9828 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0064 | 0.0019 | 0.0017 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.009 | 0.0088 | 0.0086 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.0088 | 0.0088 |
Chlamydia trachomatis | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | 0.0063 | 0.0016 | 0.5 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0078 | 0.0056 | 0.0056 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.1325 | 0.3444 | 1 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Schistosoma mansoni | nck2/grb4 | 0.0064 | 0.0019 | 0.0019 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0063 | 0.0016 | 0.5 |
Plasmodium vivax | phosphoglucomutase-2, putative | 0.0063 | 0.0016 | 0.5 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.008 | 0.0063 | 0.0063 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0016 | 0.0016 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0064 | 0.0019 | 0.0017 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3739 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0016 | 0.0014 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0063 | 0.0016 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.019 | 0.0188 |
Mycobacterium leprae | conserved hypothetical protein | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | c src tyrosine kinase | 0.009 | 0.0088 | 0.0086 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.008 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.3676 | 0.9829 | 0.9829 |
Schistosoma mansoni | nephrin | 0.0132 | 0.0203 | 0.0203 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.1595 | 0.4178 | 0.4169 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqD | 0.0063 | 0.0016 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0016 | 0.0016 |
Schistosoma mansoni | vesicular amine transporter | 0.008 | 0.0063 | 0.0063 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0063 | 0.0016 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.0147 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.0147 | 0.0145 |
Echinococcus granulosus | neuroglian | 0.0101 | 0.0119 | 0.0116 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0078 | 0.0056 | 0.0054 |
Schistosoma mansoni | cell adhesion molecule | 0.0078 | 0.0056 | 0.0056 |
Mycobacterium tuberculosis | Conserved protein | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.009 | 0.0088 | 0.0086 |
Mycobacterium leprae | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | roundabout 2 | 0.0078 | 0.0056 | 0.0054 |
Brugia malayi | Variant SH3 domain containing protein | 0.0064 | 0.0019 | 0.0049 |
Onchocerca volvulus | 0.0063 | 0.0016 | 0.0014 | |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.2207 | 0.5838 | 1 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.3739 | 1 | 1 |
Mycobacterium tuberculosis | PE-PGRS family protein PE_PGRS11 | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.009 | 0.0088 | 0.0086 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0078 | 0.0056 | 0.0156 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3739 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.009 | 0.0088 | 0.0086 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3739 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.009 | 0.0088 | 0.0086 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | Immunoglobulin | 0.008 | 0.0063 | 0.0061 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Echinococcus granulosus | twitchin | 0.0101 | 0.0119 | 0.0116 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0111 | 0.0147 | 0.0421 |
Schistosoma mansoni | 6-phosphofructokinase | 0.3739 | 1 | 1 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.009 | 0.0088 | 0.0086 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0078 | 0.0056 | 0.0054 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0078 | 0.0056 | 0.0156 |
Schistosoma mansoni | tyrosine kinase | 0.0072 | 0.0041 | 0.0041 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.0016 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0063 | 0.0016 | 0.5 |
Mycobacterium tuberculosis | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | neuroglian | 0.0078 | 0.0056 | 0.0054 |
Mycobacterium tuberculosis | Glucosyl-3-phosphoglycerate phosphatase GpgP | 0.0063 | 0.0016 | 0.5 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0063 | 0.0016 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0016 | 0.0016 |
Mycobacterium leprae | conserved hypothetical protein | 0.0063 | 0.0016 | 0.5 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.2207 | 0.5838 | 1 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0078 | 0.0056 | 0.0054 |
Echinococcus multilocularis | Immunoglobulin | 0.008 | 0.0063 | 0.0061 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1595 | 0.4178 | 0.4169 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0078 | 0.0056 | 0.0156 |
Echinococcus granulosus | roundabout 2 | 0.0078 | 0.0056 | 0.0054 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.009 | 0.0088 | 0.025 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0063 | 0.0016 | 0.0014 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0078 | 0.0056 | 0.0054 |
Echinococcus multilocularis | roundabout 2 | 0.0158 | 0.0274 | 0.0272 |
Echinococcus multilocularis | roundabout 2 | 0.0078 | 0.0056 | 0.0054 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0063 | 0.0016 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.2143 | 0.5667 | 0.5666 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.009 | 0.0088 | 0.0086 |
Mycobacterium leprae | POSSIBLE HYDROLASE MUTT1 | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.009 | 0.0088 | 0.0086 |
Onchocerca volvulus | 0.0063 | 0.0016 | 0.0014 | |
Plasmodium falciparum | phosphoglycerate mutase, putative | 0.0063 | 0.0016 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.2207 | 0.5838 | 0.5 |
Brugia malayi | hypothetical protein | 0.0111 | 0.0147 | 0.0421 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0063 | 0.0061 |
Echinococcus multilocularis | neuroglian | 0.0101 | 0.0119 | 0.0116 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0064 | 0.0019 | 0.0019 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0064 | 0.0019 | 0.0049 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Schistosoma mansoni | neuroglian | 0.0078 | 0.0056 | 0.0056 |
Treponema pallidum | phosphoglyceromutase | 0.0063 | 0.0016 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase MutT1 | 0.0063 | 0.0016 | 0.5 |
Loa Loa (eye worm) | SRC-1 | 0.009 | 0.0088 | 0.0086 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.009 | 0.0088 | 0.0086 |
Echinococcus granulosus | neuroglian | 0.0078 | 0.0056 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.019 | 0.0188 |
Toxoplasma gondii | phosphoglycerate mutase PGMII | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | Immunoglobulin | 0.008 | 0.0063 | 0.0061 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Loa Loa (eye worm) | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Brugia malayi | UBASH3A protein homolog | 0.0063 | 0.0016 | 0.0039 |
Onchocerca volvulus | 0.0063 | 0.0016 | 0.0014 | |
Schistosoma mansoni | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0064 | 0.0019 | 0.0017 |
Schistosoma mansoni | cell adhesion molecule | 0.0078 | 0.0056 | 0.0056 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.3676 | 0.9829 | 0.9828 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0078 | 0.0056 | 0.0054 |
Schistosoma mansoni | adapter molecule crk | 0.0064 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0019 | 0.0017 |
Plasmodium falciparum | phosphoglucomutase-2 | 0.0063 | 0.0016 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0056 | 0.0054 |
Mycobacterium ulcerans | hypothetical protein | 0.2207 | 0.5838 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.009 | 0.0088 | 0.0086 |
Mycobacterium leprae | Possible phosphoglycerate mutase | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.3739 | 1 | 1 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0063 | 0.0016 | 0.0014 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0078 | 0.0056 | 0.0054 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0063 | 0.0016 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3676 | 0.9829 | 0.9828 |
Brugia malayi | SRC-1 | 0.009 | 0.0088 | 0.025 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0063 | 0.0016 | 0.0014 |
Echinococcus granulosus | contactin | 0.0078 | 0.0056 | 0.0054 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 0.0088 | 0.0088 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0107 | 0.0134 | 0.0132 |
Echinococcus granulosus | defective proboscis extension response | 0.008 | 0.0063 | 0.0061 |
Onchocerca volvulus | Protein UBASH3A homolog | 0.0063 | 0.0016 | 0.0014 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0063 | 0.0016 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0134 | 0.0132 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1595 | 0.4178 | 0.4169 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0016 | 0.0014 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0063 | 0.0016 | 0.5 |
Echinococcus multilocularis | NCK adaptor protein | 0.0064 | 0.0019 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0016 | 0.0014 |
Echinococcus granulosus | NCK adaptor protein | 0.0064 | 0.0019 | 0.0017 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0063 | 0.0016 | 0.0014 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.0014 |
Mycobacterium leprae | probable isochorismate synthase EntC | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.009 | 0.0088 | 0.0086 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) | 0.0063 | 0.0016 | 0.5 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.1325 | 0.3444 | 0.3443 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0063 | 0.0061 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0063 | 0.0016 | 0.0014 |
Toxoplasma gondii | phosphoglycerate mutase | 0.0063 | 0.0016 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0063 | 0.0016 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.009 | 0.0088 | 0.0086 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.009 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0064 | 0.0019 | 0.0017 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.009 | 0.0088 | 0.0086 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0063 | 0.0016 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0016 | 0.0016 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0111 | 0.0147 | 0.0421 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0064 | 0.0019 | 0.0019 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.009 | 0.0088 | 0.0086 |
Giardia lamblia | Hypothetical protein | 0.2207 | 0.5838 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0016 | 0.0014 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.1239 | 0.321 | 0.3209 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) | 0.0063 | 0.0016 | 0.5 |
Entamoeba histolytica | phosphoglycerate mutase family protein. putative | 0.0063 | 0.0016 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0016 | 0.0016 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.009 | 0.0088 | 0.0086 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.