Detailed information for compound 678183

Basic information

Technical information
  • TDR Targets ID: 678183
  • Name: ZINC01149718
  • MW: 379.065 | Formula: C15H11Cl4NO2
  • H donors: 1 H acceptors: 1 LogP: 5.67 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cc(Cl)c(cc1Cl)Cl)COc1ccc(c(c1)C)Cl
  • InChi: 1S/C15H11Cl4NO2/c1-8-4-9(2-3-10(8)16)22-7-15(21)20-14-6-12(18)11(17)5-13(14)19/h2-6H,7H2,1H3,(H,20,21)
  • InChiKey: BZDFVBULQGOKFU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Oprea1_357125

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0227 0.0637
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0145 0.0871
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0308 0.0283
Brugia malayi Latrophilin receptor protein 2 0.0102 0.1054 0.2958
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0622 0.0597
Echinococcus multilocularis dna polymerase eta 0.002 0.0115 0.0507
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0026 0.0116
Schistosoma mansoni DNA polymerase eta 0.002 0.0115 0.048
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0424 0.1024
Leishmania major hypothetical protein, conserved 0.0053 0.05 0.6845
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0308 0.1172
Schistosoma mansoni sugar transporter 0.0029 0.0227 0.0946
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0308 0.1172
Brugia malayi hypothetical protein 0.0042 0.0369 0.1034
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0622 0.0597
Entamoeba histolytica hypothetical protein 0.0042 0.0369 0.0881
Echinococcus multilocularis muscleblind protein 1 0.0151 0.1619 0.7118
Loa Loa (eye worm) hypothetical protein 0.0034 0.0284 0.0798
Leishmania major glucose transporter, lmgt1 0.0065 0.0631 0.868
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0102 0.1054 0.2958
Loa Loa (eye worm) hypothetical protein 0.0037 0.0308 0.0865
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0115 0.1464
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0026 0.0074
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0115 0.048
Loa Loa (eye worm) hypothetical protein 0.0057 0.0546 0.1533
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0607 0.1495
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0025 0.0177 0.0151
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0607 0.2669
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0308 0.0913
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0227 0.303
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.0074
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0622 0.0597
Giardia lamblia Thioredoxin reductase 0.0145 0.1549 0.3921
Trichomonas vaginalis chaperonin, putative 0.0025 0.0177 0.051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0424 0.2686
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0284 0.1779
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0424 0.2686
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0209 0.2274 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0622 0.2734
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.1542 0.603
Loa Loa (eye worm) hypothetical protein 0.0074 0.0737 0.2069
Schistosoma mansoni pyruvate kinase 0.0034 0.0284 0.1184
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0725 0.1081
Loa Loa (eye worm) beta-lactamase 0.0037 0.0308 0.0865
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0725 1
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0115 0.1464
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0026 0.0074
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0209 0.2274 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0308 0.1172
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Entamoeba histolytica protein kinase, putative 0.0064 0.0622 0.1533
Schistosoma mansoni hypothetical protein 0.0171 0.1845 0.7681
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0424 0.5783
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Entamoeba histolytica hypothetical protein 0.0042 0.0369 0.0881
Echinococcus granulosus transient receptor potential ion channel A 0.0193 0.2088 0.9184
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0094 0.0067
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0115 0.068
Leishmania major hypothetical protein, conserved 0.0037 0.0308 0.4167
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0622 0.2734
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0177 0.0496
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0622 0.0925
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0284 0.0414
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0622 0.0597
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0369 0.1621
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.1473 0.4132
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.05 0.6845
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Echinococcus multilocularis transient receptor potential ion channel A 0.0193 0.2088 0.9184
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0284 0.383
Schistosoma mansoni transient receptor potential channel 4 0.0199 0.2164 0.9009
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0622 0.2734
Brugia malayi Transient-receptor-potential like protein 0.0074 0.0737 0.2069
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0284 0.0839
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0308 0.4167
Echinococcus multilocularis pyruvate kinase 0.0018 0.0094 0.0411
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0308 0.0913
Mycobacterium ulcerans hypothetical protein 0.0037 0.0308 0.1935
Leishmania major protein kinase, putative 0.0064 0.0622 0.855
Toxoplasma gondii sugar transporter ST1 0.0029 0.0227 0.0327
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0424 0.1765
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0424 0.2611
Echinococcus multilocularis dna polymerase kappa 0.002 0.0115 0.0507
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0338 0.3741 0.3724
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0209 0.2274 1
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0145 0.0365
Trypanosoma brucei sugar transporter, putative 0.0029 0.0227 0.303
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0227 0.0852
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0101 0.0285
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0104 0.1079 0.4745
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0104 0.1079 0.3028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0308 0.0913
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Entamoeba histolytica hypothetical protein 0.01 0.1035 0.2598
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0026 0.0074
Echinococcus multilocularis muscleblind protein 0.0151 0.1619 0.7118
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0209 0.2274 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Toxoplasma gondii sugar transporter ST2 0.0029 0.0227 0.0327
Loa Loa (eye worm) hypothetical protein 0.0047 0.0424 0.1189
Schistosoma mansoni glucose transport protein 0.0209 0.2274 0.9465
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0026 0.0074
Echinococcus granulosus short transient receptor potential channel 6 0.0132 0.1395 0.6135
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0284 0.0798
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0145 0.1549 0.472
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0284 0.383
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Echinococcus granulosus muscleblind protein 0.0151 0.1619 0.7118
Loa Loa (eye worm) T-complex protein 1 0.0025 0.0177 0.0496
Schistosoma mansoni hypothetical protein 0.0102 0.1054 0.4388
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0631 0.868
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0101 0.0075
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0025 0.0177 0.0387
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0284 0.0839
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0607 0.1703
Trichomonas vaginalis conserved hypothetical protein 0.0209 0.2274 0.6944
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0369 0.1534
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0358 0.1067
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0227 0.0664
Plasmodium falciparum protein kinase 7 0.059 0.6621 0.6612
Plasmodium falciparum mitogen-activated protein kinase 2 0.0338 0.3741 0.3724
Loa Loa (eye worm) hypothetical protein 0.0199 0.2164 0.6072
Echinococcus multilocularis General substrate transporter 0.018 0.1939 0.8527
Toxoplasma gondii facilitative glucose transporter GT1 0.0209 0.2274 0.3424
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0576 0.2535
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0284 0.0259
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0227 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0227 0.0664
Giardia lamblia Pyruvate kinase 0.0018 0.0094 0.0173
Treponema pallidum thioredoxin reductase (trxB) 0.0145 0.1549 0.4694
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0424 0.1864
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0145 0.1549 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Echinococcus granulosus lamin dm0 0.0057 0.0546 0.2403
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0166 0.0359
Trypanosoma brucei glucose transporter 1E 0.0065 0.0631 0.868
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.1542 0.9957
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0607 0.3875
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.05 0.074
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0101 0.0137
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0115 0.1464
Echinococcus granulosus solute carrier family 22 0.0029 0.0227 0.0999
Toxoplasma gondii t-complex protein beta subunit 0.0025 0.0177 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0631 0.1903
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0227 0.0999
Schistosoma mansoni hypothetical protein 0.0102 0.1054 0.4388
Echinococcus multilocularis short transient receptor potential channel 6 0.0132 0.1395 0.6135
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0046 0.0496
Giardia lamblia Sugar-proton symporter 0.0029 0.0227 0.0517
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0145 0.0778
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.022 0.2402 0.674
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0227 0.0664
Brugia malayi MH2 domain containing protein 0.0139 0.1473 0.4132
Entamoeba histolytica hypothetical protein 0.0047 0.0424 0.1024
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0026 0.0218
Brugia malayi latrophilin 2 splice variant baaae 0.022 0.2402 0.674
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0308 0.1935
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0607 0.2526
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0104 0.1079 0.4492
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0607 0.1495
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.01 0.1035 0.2598
Schistosoma mansoni pyruvate kinase 0.0034 0.0284 0.1184
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0227 0.0852
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0308 0.1172
Schistosoma mansoni transient receptor potential channel 0.0199 0.2164 0.9009
Schistosoma mansoni hypothetical protein 0.0171 0.1845 0.7681
Toxoplasma gondii ABC1 family protein 0.0037 0.0308 0.045
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0115 0.1464
Echinococcus granulosus solute carrier family 22 0.0029 0.0227 0.0999
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0725 1
Schistosoma mansoni sugar transporter 0.0029 0.0227 0.0946
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0115 0.0507
Brugia malayi hypothetical protein 0.0029 0.0227 0.0637
Loa Loa (eye worm) hypothetical protein 0.0063 0.0607 0.1703
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0115 0.1464
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0227 0.303
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0308 0.1284
Schistosoma mansoni transient receptor potential channel 0.0132 0.1395 0.5807
Echinococcus multilocularis GPCR, family 2 0.0102 0.1054 0.4636
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0025 0.0177 0.0778
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Echinococcus multilocularis geminin 0.0171 0.1845 0.8115
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0165 0.0725
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0424 0.1864
Plasmodium falciparum hexose transporter 0.0209 0.2274 0.2253
Schistosoma mansoni lamin 0.0057 0.0546 0.2275
Echinococcus multilocularis lamin 0.0057 0.0546 0.2403
Echinococcus multilocularis pyruvate kinase 0.0018 0.0094 0.0411
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0227 0.0637
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0177 0.0496
Loa Loa (eye worm) latrophilin receptor protein 2 0.0102 0.1054 0.2958
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0025 0.0177 0.2324
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0101 0.0075
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0227 0.1407
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0322 0.3564 1
Echinococcus multilocularis lamin dm0 0.0057 0.0546 0.2403
Loa Loa (eye worm) hypothetical protein 0.0037 0.0308 0.0865
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0227 0.0664
Echinococcus multilocularis solute carrier family 22 0.0029 0.0227 0.0999
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0115 0.1464
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.05 0.6845
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0338 0.3741 0.5643
Brugia malayi major facilitator superfamily protein 0.0029 0.0227 0.0637
Echinococcus granulosus pyruvate kinase 0.0034 0.0284 0.125
Echinococcus multilocularis solute carrier family 22 0.0029 0.0227 0.0999
Schistosoma mansoni protein kinase 0.0064 0.0622 0.2587
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0607 0.2526
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0284 0.383
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0622 0.0597
Mycobacterium tuberculosis Conserved protein 0.0037 0.0308 0.1172
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0308 0.4167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0104 0.1079 0.4492
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0145 0.1549 0.472
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Echinococcus granulosus geminin 0.0171 0.1845 0.8115
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0424 0.5783
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0101 0.127
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0209 0.2274 1
Echinococcus granulosus short transient receptor potential channel 6 0.0132 0.1395 0.6135
Echinococcus multilocularis pyruvate kinase 0.0034 0.0284 0.125
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0101 0.127
Loa Loa (eye worm) hypothetical protein 0.0056 0.0534 0.15
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0025 0.0177 0.051
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0208 0.0915
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0284 0.179
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Brugia malayi beta-lactamase 0.0037 0.0308 0.0865
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0115 0.0321
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0308 0.1356
Trypanosoma cruzi hexose transporter 0.0065 0.0631 0.868
Schistosoma mansoni hypothetical protein 0.0209 0.2274 0.9465
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0177 0.0736
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0284 0.1779
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Loa Loa (eye worm) hypothetical protein 0.0067 0.0661 0.1856
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0308 0.0865
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0104 0.1079 0.4492
Echinococcus multilocularis calcium activated potassium channel 0.0011 0.0014 0.006
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0227 0.303
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0115 0.0324
Echinococcus granulosus lamin 0.0057 0.0546 0.2403
Loa Loa (eye worm) sugar transporter 0.0029 0.0227 0.0637
Schistosoma mansoni lamin 0.0057 0.0546 0.2275
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0046 0.0496
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0725 0.0701
Brugia malayi Sugar transporter family protein 0.0029 0.0227 0.0637
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0227 0.1319
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0631 0.1903
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0622 0.2734
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0101 0.0446
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Brugia malayi hypothetical protein 0.0034 0.0284 0.0798
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0631 0.868
Trypanosoma brucei unspecified product 0.0013 0.0046 0.0496
Schistosoma mansoni hypothetical protein 0.022 0.2402 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0308 0.1356
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0145 0.1549 1
Loa Loa (eye worm) sugar transporter 0.0209 0.2274 0.638
Toxoplasma gondii protein kinase, putative 0.059 0.6621 1
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0227 0.0637
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0424 0.2686
Entamoeba histolytica protein kinase, putative 0.0064 0.0622 0.1533
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0227 0.303
Trypanosoma brucei unspecified product 0.002 0.0115 0.1464
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0209 0.2274 1
Echinococcus granulosus pyruvate kinase 0.0018 0.0094 0.0411
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0094 0.0067
Schistosoma mansoni hypothetical protein 0.0024 0.0165 0.0686
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0308 0.0865
Schistosoma mansoni protein kinase 0.0064 0.0622 0.2587
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0243 0.0681
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Leishmania major pyruvate kinase 0.0034 0.0284 0.383
Echinococcus granulosus dna polymerase kappa 0.002 0.0115 0.0507
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0115 0.068
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Schistosoma mansoni hypothetical protein 0.0102 0.1054 0.4388
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0227 0.0999
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0101 0.127
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0104 0.1079 0.4745
Giardia lamblia Hexose transporter 0.0029 0.0227 0.0517
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0631 0.868
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0725 0.0701
Schistosoma mansoni sugar transporter 0.0029 0.0227 0.0946
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0227 0.0999
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0101 0.0285
Chlamydia trachomatis pyruvate kinase 0.0034 0.0284 0.1695
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0227 0.0946
Echinococcus granulosus GPCR family 2 0.0102 0.1054 0.4636
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0209 0.2274 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0284 0.1077
Loa Loa (eye worm) hypothetical protein 0.0024 0.0166 0.0465
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0227 0.0637
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0115 0.0324
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0026 0.0116
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0115 0.1464
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0026 0.0101
Echinococcus multilocularis solute carrier family 22 0.0029 0.0227 0.0999
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0227 0.0664
Loa Loa (eye worm) hypothetical protein 0.0064 0.0622 0.1744
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.05 0.0475
Leishmania major glucose transporter, lmgt2 0.0065 0.0631 0.868
Leishmania major glucose transporter, lmgt3 0.0065 0.0631 0.868
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0308 0.1284
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0102 0.1054 0.4636
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0101 0.0422
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0101 0.0137
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0101 0.127
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0424 0.1765
Giardia lamblia DINP protein human, muc B family 0.002 0.0115 0.0229
Schistosoma mansoni transient receptor potential channel 0.0132 0.1395 0.5807
Plasmodium falciparum T-complex protein 1 subunit beta 0.0025 0.0177 0.0151
Mycobacterium tuberculosis Conserved protein 0.0037 0.0308 0.1172
Brugia malayi major facilitator superfamily protein 0.0029 0.0227 0.0637
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0026 0.0218
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0101 0.0446
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0074 0.0737 0.3242
Loa Loa (eye worm) hypothetical protein 0.0063 0.0607 0.1703
Brugia malayi Muscleblind-like protein 0.0151 0.1619 0.4542
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0607 0.1703
Mycobacterium leprae Probable lipase LipE 0.0037 0.0308 0.1935
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0308 0.1172
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0344 0.1311
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.05 0.0475
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0166 0.0465
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0101 0.0446
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0208 0.0915
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0308 0.1172
Onchocerca volvulus 0.0057 0.0546 1
Onchocerca volvulus 0.0037 0.0308 0.2544
Leishmania major DNA polymerase eta, putative 0.002 0.0115 0.1464
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0026 0.0116
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0026 0.0218
Entamoeba histolytica hypothetical protein 0.0042 0.0369 0.0881
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0424 0.0399
Trypanosoma brucei glucose transporter, putative 0.0065 0.0631 0.868
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0025 0.0177 0.0778
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0186 0.0521
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0631 0.1903
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0631 0.868
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0546 0.1533
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0622 0.1874
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0308 0.4167
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0102 0.1054 0.4636
Echinococcus granulosus General substrate transporter 0.018 0.1939 0.8527
Schistosoma mansoni glucose transport protein 0.0209 0.2274 0.9465
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0101 0.0357
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Brugia malayi beta-lactamase family protein 0.0037 0.0308 0.0865
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Mycobacterium ulcerans sugar transporter 0.0029 0.0227 0.1407
Plasmodium falciparum pyruvate kinase 0.0034 0.0284 0.0259
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Schistosoma mansoni hypothetical protein 0.0102 0.1054 0.4388
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0101 0.0446
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0725 1
Mycobacterium ulcerans lipase LipD 0.0037 0.0308 0.1935
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0622 0.0597
Schistosoma mansoni hypothetical protein 0.0042 0.0369 0.1534
Leishmania major DNA polymerase kappa, putative 0.002 0.0115 0.1464
Loa Loa (eye worm) hypothetical protein 0.0102 0.1054 0.2958
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0102 0.1054 0.4636
Loa Loa (eye worm) hypothetical protein 0.002 0.0115 0.0324
Entamoeba histolytica thioredoxin reductase, putative 0.0145 0.1549 0.3921
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0102 0.1054 0.4636
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0115 0.0412
Giardia lamblia TCP-1 chaperonin subunit beta 0.0025 0.0177 0.0387
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0622 0.1744
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0308 0.1935
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0546 0.1533
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0284 0.0798
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0115 0.1464
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0227 0.0637
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Loa Loa (eye worm) hypothetical protein 0.0125 0.1319 0.3701
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0227 0.0664
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0101 0.0446
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.327 0.8352
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0424 0.1268
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Brugia malayi isocitrate dehydrogenase 0.0018 0.0101 0.0285
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0209 0.2274 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.05 0.0475
Loa Loa (eye worm) hypothetical protein 0.0037 0.0308 0.0865
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0165 0.0725
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0344 0.1311
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0622 0.1744
Toxoplasma gondii sugar transporter ST3 0.0029 0.0227 0.0327
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0145 0.1549 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0308 0.0913
Schistosoma mansoni glucose transport protein 0.0209 0.2274 0.9465
Treponema pallidum fructose-bisphosphate aldolase 0.0296 0.327 1
Loa Loa (eye worm) hypothetical protein 0.0322 0.3564 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0308 0.1172
Echinococcus multilocularis pyruvate kinase 0.0027 0.0202 0.0887
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0284 0.0798
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Schistosoma mansoni sugar transporter 0.0029 0.0227 0.0946
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0284 0.383
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0607 0.1829
Echinococcus multilocularis pyruvate kinase 0.0018 0.0094 0.0411
Echinococcus granulosus pyruvate kinase 0.0034 0.0284 0.125
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.1542 0.9957
Giardia lamblia Fructose-bisphosphate aldolase 0.0296 0.327 0.8352
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0026 0.0218
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.05 0.6845
Echinococcus granulosus TRP transient receptor potential channel 0.0074 0.0737 0.3242
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0308 0.0913
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0101 0.127
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0631 0.1903
Brugia malayi hypothetical protein 0.0029 0.0227 0.0637
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.327 0.8352
Trypanosoma brucei glucose transporter 2A 0.0065 0.0631 0.868
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0369 0.1621
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Schistosoma mansoni glucose transporter 0.0029 0.0227 0.0946
Loa Loa (eye worm) hypothetical protein 0.0151 0.1619 0.4542
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0115 0.0324
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0104 0.1079 0.4745
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0115 0.1464
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0026 0.011
Echinococcus multilocularis short transient receptor potential channel 6 0.0132 0.1395 0.6135
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0622 0.0925
Echinococcus granulosus pyruvate kinase 0.0018 0.0094 0.0411
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0308 0.1172
Schistosoma mansoni intermediate filament proteins 0.0057 0.0546 0.2275
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0104 0.1079 0.4745
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Echinococcus granulosus solute carrier family 22 0.0029 0.0227 0.0999
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0026 0.0218
Plasmodium vivax sugar transporter, putative 0.0029 0.0227 0.0201
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0622 0.2734
Brugia malayi Cam kinase protein 1 0.0064 0.0622 0.1744
Mycobacterium ulcerans beta-lactamase 0.0037 0.0308 0.1935
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0546 0.1533
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0284 0.0798
Loa Loa (eye worm) hypothetical protein 0.0051 0.0473 0.1327
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0631 0.868
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0622 0.2734
Echinococcus granulosus transient receptor potential gamma protein 0.0199 0.2164 0.9517
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0026 0.0074
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0631 0.1903
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0622 0.0925
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0607 0.2669
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0026 0.0061
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0145 0.1549 0.472
Loa Loa (eye worm) hypothetical protein 0.0053 0.05 0.1402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0196 0.055
Schistosoma mansoni protein kinase 0.0064 0.0622 0.2587
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0576 0.2535
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0026 0.0101
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.2551 1
Trichomonas vaginalis esterase, putative 0.0037 0.0308 0.0913
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0227 0.0664
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0424 0.0625
Brugia malayi Calcitonin receptor-like protein seb-1 0.0322 0.3564 1
Leishmania major hypothetical protein, conserved 0.0029 0.0227 0.303
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0622 0.855
Plasmodium vivax CDK-related protein kinase 6, putative 0.0887 1 1
Leishmania major T-complex protein 1, beta subunit, putative 0.0025 0.0177 0.2324
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0026 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0725 1
Giardia lamblia Pyruvate kinase 0.0034 0.0284 0.0664
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0227 0.0201
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0424 0.5783
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0344 0.2165
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0424 0.1189
Loa Loa (eye worm) hypothetical protein 0.0027 0.0196 0.055
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0631 0.1903
Brugia malayi hypothetical protein 0.0053 0.05 0.1402
Echinococcus granulosus intermediate filament protein 0.0057 0.0546 0.2403
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0296 0.3994
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0622 0.0597
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0227 0.0999
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0622 0.1744
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.327 1
Leishmania major pyruvate kinase 0.0034 0.0284 0.383
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0115 0.0229
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0115 0.0412
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0424 0.0399
Chlamydia trachomatis thioredoxin reductase 0.0145 0.1549 1
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0308 0.1935
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0243 0.0681
Echinococcus multilocularis transient receptor potential gamma protein 0.0199 0.2164 0.9517
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0115 0.1464
Echinococcus multilocularis musashi 0.0057 0.0546 0.2403
Giardia lamblia DNA repair protein RAD52 0.0352 0.391 1
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0145 0.1549 0.472
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0227 0.303
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0115 0.0507
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0622 0.2734
Echinococcus granulosus calcium activated potassium channel 0.0011 0.0014 0.006
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0631 0.1903
Echinococcus granulosus pyruvate kinase 0.0018 0.0094 0.0411
Entamoeba histolytica hypothetical protein 0.0042 0.0369 0.0881
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0145 0.1549 0.472
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0177 0.0736
Loa Loa (eye worm) hypothetical protein 0.0037 0.0308 0.0865
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0227 0.0327
Brugia malayi beta-lactamase family protein 0.0037 0.0308 0.0865
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0284 0.179
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Schistosoma mansoni pyruvate kinase 0.0018 0.0094 0.0389
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0011 0.0031
Trypanosoma brucei unspecified product 0.0013 0.0046 0.0496
Plasmodium vivax hexose transporter 0.0209 0.2274 0.2253
Loa Loa (eye worm) hypothetical protein 0.0151 0.1619 0.4542
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Brugia malayi hypothetical protein 0.0029 0.0227 0.0637
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0725 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0308 0.0865
Brugia malayi Sugar transporter family protein 0.0209 0.2274 0.638
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0101 0.0446
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0622 0.0597
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0622 0.2587
Echinococcus granulosus solute carrier family 22 0.0029 0.0227 0.0999
Onchocerca volvulus 0.0037 0.0308 0.2544
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0115 0.048
Brugia malayi Sugar transporter family protein 0.0029 0.0227 0.0637
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0227 0.1407
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0115 0.0321
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0046 0.0496
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0227 0.1407
Brugia malayi intermediate filament protein 0.0057 0.0546 0.1533
Loa Loa (eye worm) hypothetical protein 0.0037 0.0308 0.0865
Onchocerca volvulus 0.0057 0.0546 1
Echinococcus multilocularis solute carrier family 22 0.0029 0.0227 0.0999
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0631 0.868
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0322 0.3564 1
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0026 0.0048
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0622 0.2734
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0622 0.0597
Onchocerca volvulus 0.0037 0.0308 0.2544
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0352 0.391 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0104 0.1079 0.3028
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0177 0.0736
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0284 0.179
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.1473 0.4132
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0284 0.0798
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0025 0.0177 0.2324
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0631 0.868
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0094 0.0125
Echinococcus granulosus dna polymerase eta 0.002 0.0115 0.0507
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0227 0.0664
Loa Loa (eye worm) hypothetical protein 0.0028 0.0208 0.0584
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0145 0.1549 0.6056
Echinococcus multilocularis pyruvate kinase 0.0034 0.0284 0.125
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0026 0.0101
Loa Loa (eye worm) hypothetical protein 0.0029 0.0227 0.0637
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0115 0.1464
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0026 0.0116

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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