Detailed information for compound 693472

Basic information

Technical information
  • TDR Targets ID: 693472
  • Name: N-[2-(2,3-dihydroindol-1-yl)-2-thiophen-2-yle thyl]-N'-(2-hydroxyethyl)oxamide
  • MW: 359.443 | Formula: C18H21N3O3S
  • H donors: 3 H acceptors: 3 LogP: 1.66 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCNC(=O)C(=O)NCC(N1CCc2c1cccc2)c1cccs1
  • InChi: 1S/C18H21N3O3S/c22-10-8-19-17(23)18(24)20-12-15(16-6-3-11-25-16)21-9-7-13-4-1-2-5-14(13)21/h1-6,11,15,22H,7-10,12H2,(H,19,23)(H,20,24)
  • InChiKey: OKUJFQWQZRRDJV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N'-(2-hydroxyethyl)-N-[2-indolin-1-yl-2-(2-thienyl)ethyl]oxamide
  • N'-(2-hydroxyethyl)-N-[2-(1-indolinyl)-2-(2-thienyl)ethyl]oxamide
  • N-[2-(2,3-dihydroindol-1-yl)-2-thiophen-2-yl-ethyl]-N'-(2-hydroxyethyl)ethanediamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0224 0.0204
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.0329 0.0491
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0168 0.0235
Mycobacterium ulcerans lipase LipD 0.0117 0.0816 0.1527
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0168 0.024
Mycobacterium ulcerans hypothetical protein 0.0691 0.5229 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0113 0.0183
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.0329 0.0502
Toxoplasma gondii phosphotransferase enzyme family protein 0.0048 0.0288 0.0773
Loa Loa (eye worm) hypothetical protein 0.0117 0.0816 0.1322
Schistosoma mansoni hypothetical protein 0.0401 0.3001 0.4847
Brugia malayi hypothetical protein 0.0037 0.0201 0.0293
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0136 0.0188
Echinococcus granulosus G protein coupled receptor kinase 1 0.0084 0.0565 0.0886
Brugia malayi nuclear receptor RXR 0.0025 0.0113 0.015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.0975 0.1553
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1312 1 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0152 0.0213
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0048 0.0027
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0215 0.0309
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0621 0.469 0.4679
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.005 0.0302 1
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.0329 0.0491
Loa Loa (eye worm) hypothetical protein 0.0813 0.617 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.0329 0.0534
Brugia malayi hypothetical protein 0.0025 0.0113 0.015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.0329 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0302 0.1715
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0329 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.0816 0.0797
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0113 0.015
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.0329 0.0502
Onchocerca volvulus 0.0137 0.0975 0.2446
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.071 0.1121
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0224 0.127
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0137 0.0975 0.1553
Onchocerca volvulus 0.0484 0.3639 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0586 0.1005
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0033 0.0021
Loa Loa (eye worm) beta-lactamase 0.0117 0.0816 0.1322
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0113 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0204 0.1158
Brugia malayi ecdysteroid receptor 0.0053 0.0329 0.0502
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0653 0.1028
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0208 0.0188
Schistosoma mansoni hypothetical protein 0.0032 0.0168 0.024
Mycobacterium tuberculosis Probable esterase LipL 0.0117 0.0816 0.1413
Echinococcus multilocularis choline:ethanolamine kinase 0.0495 0.3727 0.5886
Trichomonas vaginalis penicillin-binding protein, putative 0.0117 0.0816 0.4629
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0586 0.1005
Loa Loa (eye worm) choline/ethanolamine kinase 0.0048 0.0288 0.0467
Brugia malayi tailless protein 0.0025 0.0113 0.015
Toxoplasma gondii phosphotransferase enzyme family protein 0.0048 0.0288 0.0773
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.0329 0.0502
Loa Loa (eye worm) hypothetical protein 0.0484 0.3639 0.5898
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.0329 0.0614
Mycobacterium ulcerans beta-lactamase 0.0117 0.0816 0.1527
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0653 0.1028
Schistosoma mansoni acetylcholinesterase 0.0137 0.0975 0.1553
Loa Loa (eye worm) hypothetical protein 0.0137 0.0975 0.1581
Echinococcus multilocularis acetylcholinesterase 0.0813 0.617 0.9766
Echinococcus granulosus acetylcholinesterase 0.0813 0.617 1
Loa Loa (eye worm) hypothetical protein 0.0137 0.0975 0.1581
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0113 0.015
Echinococcus granulosus ethanolamine kinase 2 0.0048 0.0288 0.0435
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0021 0.0055
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0136 0.0188
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Loa Loa (eye worm) carboxylesterase 0.0813 0.617 1
Mycobacterium tuberculosis Probable reductase 0.0087 0.0586 0.1005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.0329 0.0502
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0201 0.0293
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0136 0.0188
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0136 0.0188
Brugia malayi Carboxylesterase family protein 0.0137 0.0975 0.1553
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1312 1 1
Onchocerca volvulus 0.024 0.1762 0.4678
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0168 0.0273
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.0329 0.0502
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.005 0.0302 0.0458
Leishmania major choline kinase 0.0048 0.0288 0.0268
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0208 0.1181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0176 0.0999
Plasmodium falciparum glutathione reductase 0.0038 0.0211 0.0515
Mycobacterium tuberculosis Probable lipase LipD 0.0117 0.0816 0.1413
Trichomonas vaginalis D-aminoacylase, putative 0.0117 0.0816 0.4629
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0048 0.0027
Echinococcus granulosus acetylcholinesterase 0.0813 0.617 1
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0113 0.015
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.0329 0.0502
Schistosoma mansoni thyroid hormone receptor 0.0454 0.3411 0.5514
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0745 0.5647 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0117 0.0816 0.4629
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0113 0.015
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.005 0.0302 0.0447
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0211 0.0191
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0204 0.0548
Loa Loa (eye worm) hypothetical protein 0.003 0.0152 0.0246
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.005 0.0302 0.0282
Schistosoma mansoni choline/ethanolamine kinase 0.0048 0.0288 0.0435
Echinococcus granulosus GPCR family 2 0.0032 0.0168 0.024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0152 0.0213
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Trypanosoma cruzi choline ethanolamine kinase, putative 0.0048 0.0288 0.0268
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0048 0.0077
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0021 0.0117
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.0329 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0048 0.0271
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0022 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0048 0.0271
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0152 0.0208
Echinococcus multilocularis para nitrobenzyl esterase 0.0137 0.0975 0.1517
Brugia malayi Pre-SET motif family protein 0.003 0.0152 0.0213
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0168 0.0235
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0113 0.015
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0113 0.015
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.0329 0.0534
Echinococcus multilocularis thyroid hormone receptor alpha 0.0454 0.3411 0.5385
Loa Loa (eye worm) glutathione reductase 0.0038 0.0211 0.0343
Schistosoma mansoni lamin 0.0028 0.0132 0.0181
Echinococcus multilocularis survival motor neuron protein 1 0.0504 0.3794 0.5993
Echinococcus multilocularis neuroligin 0.0137 0.0975 0.1517
Mycobacterium leprae conserved hypothetical protein 0.0117 0.0816 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0137 0.0975 0.5535
Brugia malayi beta-lactamase 0.0117 0.0816 0.1293
Brugia malayi hypothetical protein 0.0028 0.0136 0.0188
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0201 0.0293
Toxoplasma gondii ABC1 family protein 0.0117 0.0816 0.2189
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0208 0.036
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0184 0.1337 0.1319
Onchocerca volvulus 0.0028 0.0132 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Plasmodium vivax choline kinase, putative 0.0495 0.3727 1
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0128 0.017
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0113 0.0183
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0128 0.0207
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0832 0.6317 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0329 0.0491
Echinococcus granulosus carboxylesterase 5A 0.0813 0.617 1
Mycobacterium tuberculosis Conserved protein 0.0117 0.0816 0.1413
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0224 0.127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0715
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0033 0.0054
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0208 0.1181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0204 0.1158
Mycobacterium tuberculosis Conserved hypothetical protein 0.0691 0.5229 0.9258
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0094 0.064 0.1037
Mycobacterium leprae Probable lipase LipE 0.0117 0.0816 1
Trichomonas vaginalis choline/ethanolamine kinase, putative 0.0048 0.0288 0.1635
Echinococcus granulosus microtubule associated protein 2 0.0719 0.5443 0.8818
Onchocerca volvulus 0.0137 0.0975 0.2446
Plasmodium falciparum flap endonuclease 1 0.0027 0.0128 0.0289
Loa Loa (eye worm) hypothetical protein 0.0117 0.0816 0.1322
Onchocerca volvulus Putative choline\/ethanolamine kinase 0.0048 0.0288 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0204 0.1158
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0184 0.1337 0.1319
Brugia malayi hypothetical protein 0.0025 0.0113 0.015
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0168 0.024
Brugia malayi nuclear receptor NHR-67 0.0025 0.0113 0.015
Echinococcus multilocularis musashi 0.0028 0.0132 0.0177
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0021 0.0055
Onchocerca volvulus 0.0106 0.0735 0.1766
Brugia malayi Choline/ethanolamine kinase family protein 0.0048 0.0288 0.0435
Entamoeba histolytica choline/ethanolamine kinase, putative 0.0048 0.0288 0.9195
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0621 0.469 0.4679
Mycobacterium ulcerans carboxylesterase, LipT 0.0137 0.0975 0.1833
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0813 0.617 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0022 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0048 0.0027
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Echinococcus multilocularis GPCR, family 2 0.0032 0.0168 0.0235
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.066 0.1137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.0329 0.0534
Loa Loa (eye worm) hypothetical protein 0.0137 0.0975 0.1581
Echinococcus granulosus intermediate filament protein 0.0028 0.0132 0.0181
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0113 0.015
Mycobacterium ulcerans esterase/lipase LipP 0.0117 0.0816 0.1527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.0329 0.0534
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0208 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.0329 0.0491
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0128 0.0725
Brugia malayi nuclear receptor NHR-88 0.0025 0.0113 0.015
Schistosoma mansoni hypothetical protein 0.0032 0.0168 0.024
Trichomonas vaginalis set domain proteins, putative 0.024 0.1762 1
Loa Loa (eye worm) hypothetical protein 0.0504 0.3794 0.6149
Brugia malayi nuclear receptor NHR-88 0.0053 0.0329 0.0502
Onchocerca volvulus 0.0048 0.0288 0.0497
Brugia malayi nuclear hormone receptor 0.0053 0.0329 0.0502
Trichomonas vaginalis D-aminoacylase, putative 0.0117 0.0816 0.4629
Echinococcus multilocularis beta adrenergic receptor kinase 0.0094 0.064 0.0984
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0715
Brugia malayi Carboxylesterase family protein 0.0137 0.0975 0.1553
Loa Loa (eye worm) hypothetical protein 0.0106 0.0735 0.1192
Brugia malayi hypothetical protein 0.0484 0.3639 0.5884
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0137 0.0975 0.5535
Loa Loa (eye worm) inositol-1 0.0038 0.0208 0.0337
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0178 0.028
Loa Loa (eye worm) hypothetical protein 0.0117 0.0816 0.1322
Trypanosoma brucei choline kinase 0.0048 0.0288 0.0268
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.0975 0.1553
Echinococcus multilocularis microtubule associated protein 2 0.0719 0.5443 0.8611
Echinococcus granulosus para nitrobenzyl esterase 0.0137 0.0975 0.1553
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0302 0.0458
Brugia malayi Carboxylesterase family protein 0.0813 0.617 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0208 0.0188
Loa Loa (eye worm) hypothetical protein 0.0137 0.0975 0.1581
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.4179
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0137 0.0975 0.1697
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0653 0.1028
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.005 0.0302 0.0282
Loa Loa (eye worm) hypothetical protein 0.0117 0.0816 0.1322
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0036
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0224 0.0204
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0117 0.0816 0.1413
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0211 0.0343
Brugia malayi beta-lactamase family protein 0.0117 0.0816 0.1293
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0329 0.0502
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0329 0.0502
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0586 0.6395
Plasmodium falciparum ethanolamine kinase 0.0048 0.0288 0.0722
Loa Loa (eye worm) hypothetical protein 0.0102 0.0706 0.1145
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0084 0.0565 0.0865
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0078 0.0058
Loa Loa (eye worm) hypothetical protein 0.0813 0.617 1
Mycobacterium tuberculosis Probable lipase LipE 0.0117 0.0816 0.1413
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0048 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0329 0.0502
Brugia malayi Carboxylesterase family protein 0.0813 0.617 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0713
Echinococcus granulosus neuroligin 0.0137 0.0975 0.1553
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0048 0.0027
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0113 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0827
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.0329 0.0491
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0713
Schistosoma mansoni hypothetical protein 0.0032 0.0168 0.024
Brugia malayi hypothetical protein 0.0028 0.0136 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0204 0.1158
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0653 0.1028
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0152 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0048 0.0271
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0029
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0706 0.1115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0048 0.0271
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0215 0.0317
Onchocerca volvulus 0.0137 0.0975 0.2446
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0184 0.1337 0.1319
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0117 0.0816 0.1322
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0653 0.1004
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0013 0.0021 0.5
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0128 0.0107
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.0329 0.0502
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0329 0.0502
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Mycobacterium tuberculosis Conserved protein 0.0117 0.0816 0.1413
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.0329 0.0502
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.0329 0.0502
Trypanosoma brucei hypothetical protein, conserved 0.0117 0.0816 0.0797
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0048 0.0027
Loa Loa (eye worm) hypothetical protein 0.0117 0.0816 0.1322
Onchocerca volvulus 0.0053 0.0329 0.0614
Loa Loa (eye worm) hypothetical protein 0.0028 0.0132 0.0214
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.0816 0.0797
Schistosoma mansoni lozenge 0.0061 0.0386 0.0594
Mycobacterium ulcerans hypothetical protein 0.0117 0.0816 0.1527
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0152 0.0213
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.066 0.7561
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0053 0.0329 0.0491
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0401 0.3001 0.4734
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0113 0.0146
Echinococcus multilocularis beta LACTamase domain containing family member 0.0117 0.0816 0.1263
Loa Loa (eye worm) hypothetical protein 0.0048 0.0288 0.0467
Giardia lamblia GTOR 0.005 0.0302 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0128 0.0208
Schistosoma mansoni BC026374 protein (S09 family) 0.0137 0.0975 0.1553
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0211 0.0339
Loa Loa (eye worm) hypothetical protein 0.0484 0.3639 0.5898
Echinococcus granulosus beta LACTamase domain containing family member 0.0117 0.0816 0.1293
Trypanosoma cruzi choline kinase 0.0048 0.0288 0.0268
Plasmodium vivax glutathione reductase, putative 0.0038 0.0211 0.0515
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.0329 0.0502
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.4179
Brugia malayi nuclear hormone receptor 0.0025 0.0113 0.015
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0048 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0715
Loa Loa (eye worm) hypothetical protein 0.007 0.0457 0.0741
Schistosoma mansoni microtubule-associated protein tau 0.0719 0.5443 0.8818
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0113 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0204 0.1158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0653 0.1028
Schistosoma mansoni neuroligin 3 (S09 family) 0.0137 0.0975 0.1553
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.0329 0.0502
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0208 0.4608
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.0329 0.0502
Brugia malayi steroid hormone receptor 0.0053 0.0329 0.0502
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0113 0.015
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0137 0.0975 0.1697
Onchocerca volvulus 0.0117 0.0816 0.1994
Schistosoma mansoni nuclear receptor 0.0025 0.0113 0.015
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0329 0.0502
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Loa Loa (eye worm) hypothetical protein 0.0028 0.0136 0.022
Echinococcus granulosus beta-adrenergic receptor kinase 0.0094 0.064 0.1007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0048 0.0271
Echinococcus granulosus lamin dm0 0.0028 0.0132 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0168 0.0953
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0168 0.024
Schistosoma mansoni flap endonuclease-1 0.0025 0.0108 0.0142
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0113 0.015
Echinococcus granulosus tumor protein p63 0.0725 0.5495 0.8902
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0208 0.0298
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0457 0.071
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0586 0.1005
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0148 0.084
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0148 0.084
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.064 0.1007
Brugia malayi Carboxylesterase family protein 0.0137 0.0975 0.1553
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0128 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.0329 0.0534
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.064 0.1007
Schistosoma mansoni choline kinase 0.0048 0.0288 0.0435
Toxoplasma gondii thioredoxin reductase 0.0038 0.0211 0.0567
Echinococcus multilocularis acetylcholinesterase 0.0813 0.617 0.9766
Schistosoma mansoni hypothetical protein 0.0037 0.0201 0.0293
Echinococcus multilocularis lamin dm0 0.0028 0.0132 0.0177
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0329 0.0491
Onchocerca volvulus 0.0137 0.0975 0.2446
Loa Loa (eye worm) runx1 0.0061 0.0386 0.0625
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0053 0.0329 0.0502
Leishmania major choline/ethanolamine kinase, putative 0.0048 0.0288 0.0268
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0113 0.0146
Loa Loa (eye worm) hypothetical protein 0.0137 0.0975 0.1581
Echinococcus granulosus BC026374 protein S09 family 0.0137 0.0975 0.1553
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0653 0.1004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Onchocerca volvulus 0.0117 0.0816 0.1994
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0022 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0715
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0117 0.0816 0.1527
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0224 0.127
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Trichomonas vaginalis esterase, putative 0.0117 0.0816 0.4629
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0117 0.0816 0.1293
Brugia malayi Pre-SET motif family protein 0.0211 0.1539 0.2469
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0184 0.1337 0.1319
Echinococcus multilocularis Protein lozenge 0.0061 0.0386 0.058
Schistosoma mansoni hypothetical protein 0.0032 0.0168 0.024
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.0329 0.0614
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1312 1 1
Loa Loa (eye worm) choline/ethanolamine kinase 0.0495 0.3727 0.604
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0302 0.049
Brugia malayi Carboxylesterase family protein 0.0137 0.0975 0.1553
Brugia malayi Choline/ethanolamine kinase family protein 0.0495 0.3727 0.6027
Schistosoma mansoni choline/ethanolamine kinase 0.0048 0.0288 0.0435
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0401 0.3001 0.4847
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.005 0.0302 0.0282
Plasmodium vivax ethanolamine kinase, putative 0.0048 0.0288 0.0722
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.0329 0.0614
Brugia malayi glutathione reductase 0.0038 0.0211 0.031
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.0329 0.0502
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.4179
Schistosoma mansoni gliotactin 0.0137 0.0975 0.1553
Schistosoma mansoni lamin 0.0028 0.0132 0.0181
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0021 0.0117
Loa Loa (eye worm) hypothetical protein 0.0028 0.0136 0.022
Mycobacterium tuberculosis Carboxylesterase LipT 0.0137 0.0975 0.1697
Brugia malayi conserved hypotetical protein 0.0025 0.0113 0.015
Brugia malayi ecdysone receptor 0.0025 0.0113 0.015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0113 0.015
Echinococcus multilocularis lamin 0.0028 0.0132 0.0177
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0113 0.0146
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0113 0.015
Schistosoma mansoni inositol monophosphatase 0.0038 0.0208 0.0305
Schistosoma mansoni nuclear receptor 0.0025 0.0113 0.015
Onchocerca volvulus 0.003 0.0152 0.011
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0113 0.015
Loa Loa (eye worm) carboxylesterase 0.0137 0.0975 0.1581
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0329 0.0502
Onchocerca volvulus 0.0137 0.0975 0.2446
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0208 0.0188
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0136 0.0183
Echinococcus multilocularis carboxylesterase 5A 0.0813 0.617 0.9766
Schistosoma mansoni cellular tumor antigen P53 0.0106 0.0735 0.1162
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0113 0.0146
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0048 0.0044
Schistosoma mansoni hypothetical protein 0.0103 0.071 0.1121
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.005 0.0302 0.0282
Brugia malayi Flap endonuclease-1 0.0027 0.0128 0.0174
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0048 0.0027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0132 0.0214
Entamoeba histolytica choline/ethanolamine kinase, putative 0.0048 0.0288 0.9195
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.0329 0.0502
Loa Loa (eye worm) hypothetical protein 0.0032 0.0168 0.0273
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.4179
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0201 0.0286
Trypanosoma brucei trypanothione reductase 0.0038 0.0211 0.0191
Leishmania major hypothetical protein, conserved 0.0117 0.0816 0.0797
Loa Loa (eye worm) acetylcholinesterase 1 0.0813 0.617 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0126 0.0713
Brugia malayi intermediate filament protein 0.0028 0.0132 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0224 0.127
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0208 0.0188
Echinococcus granulosus choline:ethanolamine kinase 0.0495 0.3727 0.6027
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0152 0.0213
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0224 0.0204
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0208 0.1181
Brugia malayi Steroid receptor seven-up type 2 0.0053 0.0329 0.0502
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0586 0.1005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0706 0.1115
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0117 0.0816 0.1413
Echinococcus granulosus FTZ F1 alpha 0.0053 0.0329 0.0502
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0113 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.0329 0.0534
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0117 0.0816 0.1293
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0048 0.0043
Echinococcus multilocularis tumor protein p63 0.0725 0.5495 0.8694
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.0329 0.0502
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0128 0.0289
Onchocerca volvulus 0.0117 0.0816 0.1994
Loa Loa (eye worm) hypothetical protein 0.0137 0.0975 0.1581
Echinococcus granulosus flap endonuclease 1 0.0027 0.0128 0.0174
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0621 0.469 0.4679
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0329 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0302 0.1715
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0706 0.1145
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0113 0.015
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.0329 0.0502
Loa Loa (eye worm) hypothetical protein 0.0137 0.0975 0.1581
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0128 0.0107
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0117 0.0816 0.1413
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.005 0.0302 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.005 0.0302 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0204 0.1158
Loa Loa (eye worm) carboxylesterase 0.0137 0.0975 0.1581
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.0329 0.0534
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0143 0.0199
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0113 0.0146
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1539 0.2494
Onchocerca volvulus 0.0103 0.071 0.1693
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0302 0.1715
Trichomonas vaginalis D-aminoacylase, putative 0.0117 0.0816 0.4629
Treponema pallidum NADH oxidase 0.0013 0.0021 0.5
Schistosoma mansoni thyroid hormone receptor 0.0454 0.3411 0.5514
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0224 0.127
Schistosoma mansoni zinc finger protein 0.0025 0.0113 0.015
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0225 0.1647 0.163
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0211 0.0515
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.0329 0.0502
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0329 0.0502
Brugia malayi Choline/ethanolamine kinase family protein 0.0048 0.0288 0.0435
Loa Loa (eye worm) choline Kinase A 0.0048 0.0288 0.0467
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.0975 0.1553
Echinococcus multilocularis ethanolamine kinase 2 0.0048 0.0288 0.0425
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0148 0.084
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0132 0.0214
Loa Loa (eye worm) hypothetical protein 0.0117 0.0816 0.1322
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.0329 0.0534
Plasmodium vivax hypothetical protein, conserved 0.0117 0.0816 0.2146
Toxoplasma gondii phosphotransferase enzyme family protein 0.0495 0.3727 1
Mycobacterium tuberculosis Conserved protein 0.0117 0.0816 0.1413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0827
Brugia malayi beta-lactamase family protein 0.0117 0.0816 0.1293
Plasmodium falciparum choline kinase 0.0495 0.3727 1
Toxoplasma gondii hypothetical protein 0.0212 0.1545 0.4146
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.005 0.0302 0.0282
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0183
Brugia malayi hypothetical protein 0.0137 0.0975 0.1553
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0113 0.015
Echinococcus granulosus lamin 0.0028 0.0132 0.0181
Loa Loa (eye worm) hypothetical protein 0.0028 0.0136 0.022
Schistosoma mansoni inositol monophosphatase 0.0038 0.0208 0.0305
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0128 0.0343
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0329 0.0502
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0113 0.015
Schistosoma mansoni hypothetical protein 0.007 0.0457 0.071
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0208 0.0558
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.066 0.1137
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0136 0.022
Schistosoma mansoni coup transcription factor 0.0053 0.0329 0.0502
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.0329 0.0502
Loa Loa (eye worm) hypothetical protein 0.0028 0.0136 0.022
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.0329 0.0502
Trypanosoma brucei choline/ethanolamine kinase 0.0048 0.0288 0.0268
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0168 0.024
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.01 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0246 0.1397
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0329 0.0502
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0136 0.0188
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Brugia malayi Thioredoxin reductase 0.0038 0.0211 0.031
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0586 0.1005
Plasmodium falciparum thioredoxin reductase 0.0038 0.0211 0.0515
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.005 0.0302 0.0282
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0117 0.0816 0.1293
Brugia malayi nuclear receptor RXR 0.0028 0.0136 0.0188
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0208 0.0305
Loa Loa (eye worm) hypothetical protein 0.0053 0.0329 0.0534
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.066 0.1137
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0653 0.1058
Loa Loa (eye worm) DR-78 0.0025 0.0113 0.0183
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0132 0.0181
Echinococcus granulosus survival motor neuron protein 1 0.0504 0.3794 0.6137
Brugia malayi hypothetical protein 0.0504 0.3794 0.6137
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0653 0.1028
Giardia lamblia Ethanolamine kinase, putative 0.0048 0.0288 0.9501
Schistosoma mansoni survival motor neuron protein 0.0103 0.071 0.1121
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0128 0.3806
Loa Loa (eye worm) hypothetical protein 0.0028 0.0136 0.022
Leishmania major trypanothione reductase 0.0038 0.0211 0.0191
Schistosoma mansoni intermediate filament proteins 0.0028 0.0132 0.0181
Mycobacterium tuberculosis Probable hydrolase 0.0117 0.0816 0.1413
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.0329 0.0491
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0137 0.0975 0.1517
Echinococcus multilocularis BC026374 protein (S09 family) 0.0137 0.0975 0.1517
Onchocerca volvulus 0.0028 0.0132 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0204 0.1158
Plasmodium vivax SET domain protein, putative 0.003 0.0152 0.0353
Brugia malayi Inositol-1 0.0038 0.0208 0.0305
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0152 0.0407
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0152 0.0213

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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