Detailed information for compound 695901

Basic information

Technical information
  • TDR Targets ID: 695901
  • Name: ethyl 2-[[2-[(5-pyridin-4-yl-1,3,4-oxadiazol- 2-yl)sulfanyl]acetyl]amino]benzoate
  • MW: 384.409 | Formula: C18H16N4O4S
  • H donors: 1 H acceptors: 5 LogP: 2.86 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1ccccc1NC(=O)CSc1nnc(o1)c1ccncc1
  • InChi: 1S/C18H16N4O4S/c1-2-25-17(24)13-5-3-4-6-14(13)20-15(23)11-27-18-22-21-16(26-18)12-7-9-19-10-8-12/h3-10H,2,11H2,1H3,(H,20,23)
  • InChiKey: WVOLNOYYZFYFAG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 2-[[2-[[5-(4-pyridyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetyl]amino]benzoate
  • 2-[[1-oxo-2-[[5-(4-pyridyl)-1,3,4-oxadiazol-2-yl]thio]ethyl]amino]benzoic acid ethyl ester
  • 2-[[2-[[5-(4-pyridyl)-1,3,4-oxadiazol-2-yl]thio]acetyl]amino]benzoic acid ethyl ester
  • ethyl 2-[2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanoylamino]benzoate
  • ZINC04941527

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0038 0.0342 0.0499
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0342 0.0493
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0022 0.0168 0.0168
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0611 0.6848 0.6848
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0015 0.0084 0.0107
Brugia malayi hypothetical protein 0.0316 0.3496 0.5106
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0168 0.0125
Schistosoma mansoni neuroglian 0.0013 0.0064 0.0064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0062 0.0614 0.0891
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0022 0.0168 0.0168
Echinococcus granulosus tubulin alpha 3 chain 0.0015 0.0084 0.0116
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) tubulin alpha chain 0.0015 0.0084 0.0116
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0183 0.1993 0.2822
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0071 0.0717 1
Brugia malayi Prion-like- 0.0013 0.0064 0.0094
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0064 0.0088
Echinococcus granulosus peroxidasin 0.0013 0.0065 0.0089
Echinococcus granulosus Tubulin beta 2C chain 0.0015 0.0084 0.0116
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0103 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0168 0.0125
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0022 0.0168 0.024
Echinococcus granulosus GPCR family 2 0.0033 0.0289 0.0417
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0022 0.0168 0.024
Echinococcus granulosus tubulin alpha chain 0.0015 0.0084 0.0116
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0103 0.0135
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0013 0.0064 0.0088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Trichomonas vaginalis tubulin gamma chain, putative 0.0015 0.0084 0.0107
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0062 0.0614 0.0891
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0289 0.0423
Brugia malayi Peroxidasin 0.0013 0.0065 0.0095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Schistosoma mansoni hypothetical protein 0.0177 0.1923 0.1923
Echinococcus multilocularis Tubulin alpha 1 chain 0.0015 0.0084 0.0116
Echinococcus granulosus hemicentin 1 0.0013 0.0064 0.0088
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus peroxisome assembly protein 26 0.0015 0.0084 0.0116
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0064 0.0088
Chlamydia trachomatis dihydrofolate reductase 0.0185 0.2011 0.5
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Echinococcus granulosus roundabout 2 0.0013 0.0064 0.0088
Echinococcus granulosus tubulin beta 4A class IVa 0.0015 0.0084 0.0116
Brugia malayi Tubulin gamma chain 0.0015 0.0084 0.0122
Echinococcus multilocularis tubulin alpha chain 0.0015 0.0084 0.0116
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0022 0.0168 0.024
Echinococcus multilocularis roundabout 2 0.0013 0.0064 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0611 0.6848 1
Echinococcus granulosus tubulin subunit TubB 0.0015 0.0084 0.0116
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0611 0.6848 1
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.048 0.5359 0.7825
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0012 0.0011
Echinococcus multilocularis Tubulin alpha 1 chain 0.0015 0.0084 0.0116
Brugia malayi MH2 domain containing protein 0.0125 0.133 0.1942
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0168 0.0231
Echinococcus granulosus lachesin 0.0013 0.0064 0.0088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Trichomonas vaginalis tubulin alpha chain, putative 0.0015 0.0084 0.0107
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0103 0.0144
Trypanosoma brucei alpha tubulin 0.0015 0.0084 0.0107
Schistosoma mansoni hypothetical protein 0.0071 0.0723 0.0723
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0022 0.0168 0.024
Entamoeba histolytica hypothetical protein 0.0038 0.0342 0.0382
Trypanosoma brucei alpha tubulin 0.0015 0.0084 0.0107
Echinococcus granulosus beta tubulin 0.0015 0.0084 0.0116
Brugia malayi isocitrate dehydrogenase 0.0016 0.0103 0.015
Echinococcus multilocularis tubulin alpha 3 chain 0.0015 0.0084 0.0116
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0071 0.0717 1
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0168 0.0125
Echinococcus granulosus beta tubulin 0.0015 0.0084 0.0116
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.1338
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0084 0.0107
Loa Loa (eye worm) hypothetical protein 0.0183 0.1993 0.2906
Loa Loa (eye worm) dihydrofolate reductase 0.0185 0.2011 0.2933
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0103 0.0301
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0022 0.0168 0.0125
Schistosoma mansoni tubulin subunit beta 0.0015 0.0084 0.0084
Echinococcus granulosus Tubulin beta 2C chain 0.0015 0.0084 0.0116
Brugia malayi tubulin alpha-2 chain 0.0015 0.0084 0.0122
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.133 0.1937
Echinococcus granulosus Tubulin alpha 1 chain 0.0015 0.0084 0.0116
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.1097 0.1602
Echinococcus multilocularis lachesin 0.0013 0.0064 0.0088
Brugia malayi Smad1 0.0008 0.0012 0.0018
Brugia malayi alpha-tubulin 0.0015 0.0084 0.0122
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0022 0.0168 0.0246
Schistosoma mansoni cell adhesion molecule 0.0013 0.0064 0.0064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.1338
Schistosoma mansoni tubulin subunit alpha 0.0015 0.0084 0.0084
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.133 0.1937
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Echinococcus multilocularis roundabout 2 0.0013 0.0064 0.0088
Loa Loa (eye worm) tubulin beta-1 chain 0.0015 0.0084 0.0116
Schistosoma mansoni tyrosine kinase 0.0015 0.0088 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0611 0.6848 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0022 0.0168 0.0125
Echinococcus multilocularis Tubulin beta 2C chain 0.0015 0.0084 0.0116
Schistosoma mansoni hypothetical protein 0.0033 0.0289 0.0289
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0185 0.2011 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0015 0.0084 0.0116
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0022 0.0168 0.1338
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0103 0.01
Echinococcus granulosus tubulin alpha chain 0.0015 0.0084 0.0116
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Echinococcus granulosus geminin 0.0177 0.1923 0.2804
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) Smad1 0.0008 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0104 0.1097 0.1597
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0183 0.1993 0.1993
Schistosoma mansoni septate junction protein 0.0013 0.0064 0.0064
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.0096 0.0134
Echinococcus multilocularis geminin 0.0177 0.1923 0.2804
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0289 0.0417
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0183 0.1993 0.2906
Trichomonas vaginalis CAMK family protein kinase 0.0611 0.6848 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0022 0.0168 0.0168
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus tubulin alpha chain 0.0015 0.0084 0.0116
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0103 0.0144
Schistosoma mansoni hypothetical protein 0.0033 0.0289 0.0289
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0022 0.0168 0.0168
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0168 0.0125
Echinococcus multilocularis hypothetical protein 0.0015 0.0084 0.0116
Echinococcus granulosus tubulin gamma 1 chain 0.0015 0.0084 0.0116
Loa Loa (eye worm) tubulin alpha 2 0.0008 0.0011 0.0009
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0062 0.0619 0.0898
Trichomonas vaginalis tubulin epsilon chain, putative 0.0015 0.0084 0.0107
Trypanosoma brucei epsilon tubulin 0.0015 0.0084 0.0107
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0168 0.0125
Echinococcus multilocularis tubulin alpha 1C chain 0.0015 0.0084 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.2207 0.3212
Schistosoma mansoni roundabout 0.0013 0.0064 0.0064
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0103 0.0103
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0022 0.0168 0.024
Trypanosoma brucei beta tubulin 0.0015 0.0084 0.0107
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) alpha-tubulin 0.0015 0.0084 0.0116
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus multilocularis tubulin alpha 1C chain 0.0015 0.0084 0.0116
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Schistosoma mansoni titin 0.0013 0.0064 0.0064
Trichomonas vaginalis tubulin gamma chain, putative 0.0015 0.0084 0.0107
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.048 0.5359 0.7825
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0064 0.0088
Trichomonas vaginalis tubulin alpha chain, putative 0.0015 0.0084 0.0107
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0022 0.0168 0.024
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) tubulin beta chain 0.0015 0.0084 0.0116
Loa Loa (eye worm) tubulin beta-4 chain 0.0015 0.0084 0.0116
Trichomonas vaginalis tubulin gamma chain, putative 0.0015 0.0084 0.0107
Trypanosoma brucei epsilon tubulin 0.0015 0.0084 0.0107
Schistosoma mansoni hypothetical protein 0.0177 0.1923 0.1923
Echinococcus granulosus tubulin alpha chain 0.0015 0.0084 0.0116
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0342 0.0493
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0116
Echinococcus multilocularis Tubulin beta 2C chain 0.0015 0.0084 0.0116
Entamoeba histolytica hypothetical protein 0.0038 0.0342 0.0382
Echinococcus granulosus tubulin subunit beta 0.0015 0.0084 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0013 0.0013
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0103 0.0144
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0012
Echinococcus multilocularis peroxidasin 0.0013 0.0065 0.0089
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0084 0.0107
Loa Loa (eye worm) hypothetical protein 0.0071 0.0723 0.105
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0022 0.0168 0.0168
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Echinococcus granulosus tubulin alpha chain 0.0015 0.0084 0.0116
Onchocerca volvulus Serine\/threonine kinase homolog 0.0611 0.6848 1
Echinococcus granulosus roundabout 2 0.0013 0.0064 0.0088
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0344 0.3819 0.5575
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0168 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0611 0.6848 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0022 0.0168 0.0125
Brugia malayi Tubulin alpha-2 chain 0.0015 0.0084 0.0122
Echinococcus granulosus titin 0.0009 0.0013 0.0012
Trypanosoma cruzi polo-like protein kinase, putative 0.0611 0.6848 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0022 0.0168 0.0246
Echinococcus multilocularis tubulin alpha chain 0.0015 0.0084 0.0116
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0013 0.0064 0.0088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Trypanosoma brucei polo-like protein kinase 0.0611 0.6848 1
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0022 0.0168 0.0168
Echinococcus granulosus tubulin alpha 0.0015 0.0084 0.0116
Echinococcus multilocularis tyrosine protein kinase otk 0.0013 0.0064 0.0088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Trypanosoma brucei beta tubulin 0.0015 0.0084 0.0107
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus multilocularis tubulin subunit beta 0.0015 0.0084 0.0116
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0022 0.0168 0.0125
Schistosoma mansoni alpha tubulin 0.0015 0.0084 0.0084
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0084 0.0107
Schistosoma mansoni hypothetical protein 0.0033 0.0289 0.0289
Schistosoma mansoni tubulin subunit alpha 0.0015 0.0084 0.0084
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0013 0.0064 0.0079
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0723 0.1056
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0103 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.2207 0.3212
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0022 0.0168 0.024
Loa Loa (eye worm) beta-tubulin 0.0015 0.0084 0.0116
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0012 0.0012
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0084 0.0107
Loa Loa (eye worm) hypothetical protein 0.0013 0.0065 0.0089
Echinococcus multilocularis beta tubulin 0.0015 0.0084 0.0116
Schistosoma mansoni septate junction protein 0.0013 0.0064 0.0064
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0342 0.0342
Schistosoma mansoni dihydrofolate reductase 0.0185 0.2011 0.2011
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0022 0.0168 0.024
Entamoeba histolytica hypothetical protein 0.0038 0.0342 0.0382
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0022 0.0168 0.0246
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0012
Schistosoma mansoni tubulin subunit beta 0.0015 0.0084 0.0084
Echinococcus granulosus Tubulin alpha 1 chain 0.0015 0.0084 0.0116
Schistosoma mansoni tubulin subunit epsilon 0.0015 0.0084 0.0084
Echinococcus granulosus alpha tubulin 0.0015 0.0084 0.0116
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0022 0.0168 0.024
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0103 0.0028
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Leishmania major hypothetical protein, conserved 0.0022 0.0168 0.0125
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus granulosus tubulin alpha 1C chain 0.0015 0.0084 0.0116
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0103 0.0301
Brugia malayi Tubulin alpha-2 chain 0.0015 0.0084 0.0122
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.1338
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0022 0.0168 0.0125
Entamoeba histolytica serine/threonine protein kinase, putative 0.0611 0.6848 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0183 0.1993 0.2906
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0168 0.0231
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus multilocularis tubulin epsilon chain 0.0015 0.0084 0.0116
Trichomonas vaginalis tubulin epsilon chain, putative 0.0015 0.0084 0.0107
Echinococcus granulosus neuroglian 0.0013 0.0064 0.0088
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0185 0.2011 0.5
Loa Loa (eye worm) tubulin beta-2A chain 0.0015 0.0084 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus multilocularis Smad4 0.0008 0.0012 0.0011
Schistosoma mansoni Smad4 0.0008 0.0012 0.0012
Echinococcus multilocularis neuroglian 0.0013 0.0064 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0168 0.0231
Echinococcus multilocularis Tubulin beta 2C chain 0.0015 0.0084 0.0116
Schistosoma mansoni smad 0.0008 0.0012 0.0012
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0012 0.0011
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0022 0.0168 0.0231
Trichomonas vaginalis tubulin, putative 0.0015 0.0084 0.0107
Giardia lamblia Kinase, PLK 0.0611 0.6848 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0289 0.0417
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Schistosoma mansoni tubulin subunit beta 0.0015 0.0084 0.0084
Echinococcus multilocularis Tubulin beta 2C chain 0.0015 0.0084 0.0116
Entamoeba histolytica hypothetical protein 0.0038 0.0342 0.0382
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0084 0.0107
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Brugia malayi tubulin alpha chain - mouse 0.0015 0.0084 0.0122
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0611 0.6848 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0064 0.0088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Schistosoma mansoni cell adhesion molecule 0.0013 0.0064 0.0064
Echinococcus granulosus tubulin beta 1 chain 0.0015 0.0084 0.0116
Brugia malayi serine/threonine-protein kinase plk-2 0.0611 0.6848 1
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0022 0.0168 0.0168
Echinococcus granulosus tubulin epsilon chain 0.0015 0.0084 0.0116
Echinococcus granulosus smad 0.0008 0.0012 0.0011
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0103 0.015
Trichomonas vaginalis CAMK family protein kinase 0.0611 0.6848 1
Trypanosoma brucei beta tubulin 0.0015 0.0084 0.0107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.0013 0.0018
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0012 0.0011
Echinococcus granulosus tubulin alpha 3 chain 0.0015 0.0084 0.0116
Brugia malayi Tubulin alpha chain 0.0015 0.0084 0.0122
Loa Loa (eye worm) tubulin alpha 2 0.0008 0.0011 0.0009
Echinococcus multilocularis beta tubulin 0.0015 0.0084 0.0116
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0071 0.0717 0.3316
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0013 0.0064 0.0064
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0183 0.1993 0.2906
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus multilocularis roundabout 2 0.0013 0.0064 0.0088
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0103 0.0028
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0071 0.0717 0.1033
Loa Loa (eye worm) BEN-1 protein 0.0015 0.0084 0.0116
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0022 0.0168 0.024
Schistosoma mansoni titin 0.0009 0.0013 0.0013
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0022 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0316 0.3496 0.5103
Echinococcus multilocularis titin 0.0009 0.0013 0.0012
Echinococcus granulosus Tubulin beta 2C chain 0.0015 0.0084 0.0116
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0084 0.0107
Echinococcus multilocularis dihydrofolate reductase 0.0185 0.2011 0.2933
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0611 0.6848 1
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0022 0.0168 0.024
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.1338
Giardia lamblia Hypothetical protein 0.0022 0.0168 0.0125
Loa Loa (eye worm) tubulin gamma chain 0.0015 0.0084 0.0116
Echinococcus multilocularis tubulin alpha chain 0.0015 0.0084 0.0116
Brugia malayi protein unc-22 0.0009 0.0013 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0344 0.3819 0.5578
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) BEN-1 protein 0.0015 0.0084 0.0116
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0064 0.0064
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0022 0.0168 0.0246
Echinococcus multilocularis hemicentin 1 0.0013 0.0064 0.0088
Schistosoma mansoni alpha tubulin 0.0015 0.0084 0.0084
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0289 0.0417
Brugia malayi MH2 domain containing protein 0.0008 0.0012 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0611 0.6848 1
Echinococcus multilocularis tubulin alpha chain 0.0015 0.0084 0.0116
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Schistosoma mansoni tubulin subunit gamma 0.0015 0.0084 0.0084
Schistosoma mansoni cell adhesion molecule 0.0013 0.0064 0.0064
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0183 0.1993 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0103 0.0144
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0103 0.0144
Brugia malayi Protein kinase domain containing protein 0.0062 0.0614 0.0897
Echinococcus granulosus Tubulin beta 2C chain 0.0015 0.0084 0.0116
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0183 0.1993 0.2906
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus multilocularis twitchin 0.0009 0.0013 0.0012
Trichomonas vaginalis tubulin beta chain, putative 0.0015 0.0084 0.0107
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0185 0.2011 0.5
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0022 0.0168 0.0125
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) hypothetical protein 0.0022 0.0168 0.024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0168 0.024
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0022 0.0168 0.0246
Onchocerca volvulus 0.0335 0.3713 0.5415
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus tubulin alpha 1C chain 0.0015 0.0084 0.0116
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0033 0.0289 0.0289
Schistosoma mansoni tubulin subunit beta 0.0015 0.0084 0.0084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0008 0.0004 0.0006
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0013 0.0064 0.0088
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0289 0.0417
Echinococcus multilocularis peroxisome assembly protein 26 0.0015 0.0084 0.0116
Brugia malayi beta-tubulin, identical 0.0015 0.0084 0.0122
Schistosoma mansoni tubulin subunit alpha 0.0015 0.0084 0.0084
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus multilocularis smad 0.0008 0.0012 0.0011
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0022 0.0168 0.1338
Brugia malayi Tubulin beta chain 0.0008 0.0011 0.0016
Schistosoma mansoni nephrin 0.0013 0.0064 0.0064
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0103 0.0144
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Brugia malayi dihydrofolate reductase family protein 0.0185 0.2011 0.2937
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0015 0.0084 0.0116
Trypanosoma brucei alpha tubulin 0.0015 0.0084 0.0107
Schistosoma mansoni alpha tubulin 0.0015 0.0084 0.0084
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0009 0.0013 0.0012
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Giardia lamblia hypothetical protein 0.0022 0.0168 0.0125
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0022 0.0168 0.0231
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0161 0.174 0.2536
Trypanosoma brucei tubulin gamma chain 0.0015 0.0084 0.0107
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0064 0.0088
Schistosoma mansoni hypothetical protein 0.0038 0.0342 0.0342
Brugia malayi MH1 domain containing protein 0.0008 0.0012 0.0018
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0022 0.0168 0.0125
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0022 0.0168 0.0246
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0103 0.0135
Trypanosoma brucei beta tubulin 0.0015 0.0084 0.0107
Loa Loa (eye worm) hypothetical protein 0.0013 0.0064 0.0088
Echinococcus multilocularis tubulin gamma 1 chain 0.0015 0.0084 0.0116
Echinococcus granulosus contactin 0.0013 0.0064 0.0088
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0064 0.0094
Loa Loa (eye worm) PDE1B protein 0.0022 0.0168 0.024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.1097 0.1597
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0289 0.0417
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Onchocerca volvulus 0.0316 0.3496 0.5098
Echinococcus multilocularis tubulin alpha 3 chain 0.0015 0.0084 0.0116
Echinococcus granulosus twitchin 0.0009 0.0013 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0168 0.0125
Loa Loa (eye worm) alpha-tubulin 0.0015 0.0084 0.0116
Leishmania major cAMP-specific phosphodiesterase, putative 0.0022 0.0168 0.0125
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0071 0.0717 0.0936
Echinococcus granulosus dihydrofolate reductase 0.0185 0.2011 0.2933
Echinococcus multilocularis tubulin alpha 0.0015 0.0084 0.0116
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0008 0.0011 0.0009
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Trichomonas vaginalis tubulin epsilon chain, putative 0.0015 0.0084 0.0107
Trypanosoma brucei epsilon tubulin 0.0015 0.0084 0.0107
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0071 0.0717 0.0936
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0161 0.174 0.2541
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0012 0.0011
Echinococcus granulosus Tubulin beta 2C chain 0.0015 0.0084 0.0116
Echinococcus multilocularis GPCR, family 2 0.0033 0.0289 0.0417
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0289 0.0417
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus Smad4 0.0008 0.0012 0.0011
Loa Loa (eye worm) CAMK protein kinase 0.0009 0.0013 0.0012
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0161 0.174 0.2536
Onchocerca volvulus Tyrosine kinase homolog 0.0342 0.3801 0.5544
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0161 0.174 0.2536
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0022 0.0168 0.0125
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0022 0.0168 0.024
Brugia malayi MH1 domain containing protein 0.0008 0.0012 0.0018
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0012
Trypanosoma brucei beta tubulin 0.0015 0.0084 0.0107
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0022 0.0168 0.024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0022 0.0168 0.0231
Brugia malayi MH2 domain containing protein 0.0008 0.0012 0.0018
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0103 0.0028
Trypanosoma brucei alpha tubulin 0.0015 0.0084 0.0107
Loa Loa (eye worm) tubulin alpha-2 chain 0.0015 0.0084 0.0116
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0022 0.0168 0.0231
Plasmodium vivax phosphodiesterase gamma, putative 0.0022 0.0168 0.1338
Trypanosoma cruzi polo-like protein kinase, putative 0.0611 0.6848 1
Leishmania major hypothetical protein, conserved 0.0022 0.0168 0.0125
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0064 0.0088
Onchocerca volvulus 0.0009 0.0013 0.0003
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0009 0.0013 0.0013
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.1338
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.1097 0.1602
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0022 0.0168 0.0168
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus granulosus titin 0.0009 0.0013 0.0012
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0289 0.0423
Brugia malayi Tubulin beta-1 chain 0.0015 0.0084 0.0122
Loa Loa (eye worm) tubulin alpha chain 0.0015 0.0084 0.0116
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0012 0.0011
Trichomonas vaginalis tubulin epsilon chain, putative 0.0015 0.0084 0.0107
Echinococcus multilocularis hemicentin 1 0.0013 0.0064 0.0088
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0611 0.6848 1
Plasmodium falciparum phosphodiesterase gamma, putative 0.0022 0.0168 0.1338
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Echinococcus multilocularis tubulin subunit TubB 0.0015 0.0084 0.0116
Echinococcus multilocularis tubulin alpha chain 0.0015 0.0084 0.0116
Schistosoma mansoni tubulin subunit beta 0.0015 0.0084 0.0084
Schistosoma mansoni tubulin subunit beta 0.0015 0.0084 0.0084
Brugia malayi Dihydrofolate reductase 0.0185 0.2011 0.2937
Loa Loa (eye worm) hypothetical protein 0.0022 0.0168 0.024
Echinococcus multilocularis tubulin beta 1 chain 0.0015 0.0084 0.0116
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0168 0.0231
Plasmodium falciparum phosphodiesterase delta, putative 0.0022 0.0168 0.1338
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0611 0.6848 1
Echinococcus granulosus tyrosine protein kinase otk 0.0013 0.0064 0.0088
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0022 0.0168 0.0125
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0168 0.0444
Echinococcus multilocularis Tubulin beta 2C chain 0.0015 0.0084 0.0116
Echinococcus multilocularis Tubulin alpha 1 chain 0.0015 0.0084 0.0116
Echinococcus granulosus roundabout 2 0.0013 0.0064 0.0088
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0022 0.0168 0.0168

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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