Detailed information for compound 716082

Basic information

Technical information
  • TDR Targets ID: 716082
  • Name: 2-[(4-fluorophenyl)-(4-methoxyphenyl)sulfonyl amino]-N-(pyridin-4-ylmethyl)acetamide
  • MW: 429.465 | Formula: C21H20FN3O4S
  • H donors: 1 H acceptors: 4 LogP: 2.47 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)S(=O)(=O)N(c1ccc(cc1)F)CC(=O)NCc1ccncc1
  • InChi: 1S/C21H20FN3O4S/c1-29-19-6-8-20(9-7-19)30(27,28)25(18-4-2-17(22)3-5-18)15-21(26)24-14-16-10-12-23-13-11-16/h2-13H,14-15H2,1H3,(H,24,26)
  • InChiKey: YTVSANOEVWQBJI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-fluorophenyl)-(4-methoxyphenyl)sulfonyl-amino]-N-(4-pyridylmethyl)acetamide
  • 2-[(4-fluorophenyl)-(4-methoxyphenyl)sulfonylamino]-N-(4-pyridylmethyl)acetamide
  • 2-[(4-fluorophenyl)-(4-methoxyphenyl)sulfonyl-amino]-N-(pyridin-4-ylmethyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) hypothetical protein 0.0033 0.0393 0.1283
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0131 0.1801 0.6059
Plasmodium falciparum glutathione reductase 0.0013 0.0107 0.0383
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.083
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0107 0.0383
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0175 0.2442 1
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0015 0.0132 0.0119
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0135 0.0409
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) hypothetical protein 0.0018 0.0171 0.0533
Schistosoma mansoni hypothetical protein 0.0421 0.5992 0.5986
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0014 0.0058
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0107 0.0383
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0107 0.0383
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0596 0.8528 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0171 0.0587
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0132 0.0119
Onchocerca volvulus 0.003 0.0339 0.0965
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0132 0.0119
Brugia malayi Pre-SET motif family protein 0.0211 0.2964 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0358 0.0344
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0107 0.0383
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0175 0.2442 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0132 0.0119
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0132 0.0119
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) protein tyrosine phosphatase 0.0015 0.0132 0.0401
Leishmania major DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.083
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0015 0.0132 0.0119
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0132 0.0119
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0015 0.0132 0.0119
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0184 0.0635
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0192 0.2692 0.315
Leishmania major trypanothione reductase 0.0039 0.0475 0.1897
Onchocerca volvulus 0.0015 0.0132 0.0351
Plasmodium falciparum thioredoxin reductase 0.0039 0.0475 0.1897
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1261 0.1249
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0107 0.0383
Echinococcus multilocularis phosphoglycerate kinase 1 0.0175 0.2442 0.2431
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0281 0.1099
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0259 0.083
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0184 0.0635
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0107 0.0115
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0099 0.1338 0.5479
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma brucei protein tyrosine phosphatase 1 0.0015 0.0132 0.0487
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0482 0.0469
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0192 0.2692 0.3146
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1261 0.1249
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0107 0.0383
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0107 0.0315
Loa Loa (eye worm) hypothetical protein 0.0026 0.0281 0.0904
Loa Loa (eye worm) hypothetical protein 0.0024 0.0259 0.083
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0175 0.2442 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0132 0.0119
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.1261 0.4226
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0135 0.0121
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.2442 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0015 0.0132 0.0119
Mycobacterium ulcerans hypothetical protein 0.0024 0.0259 0.0914
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0192 0.2692 0.315
Brugia malayi Phosphoglycerate kinase 0.0064 0.0841 0.2803
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0834 0.0821
Schistosoma mansoni hypothetical protein 0.0011 0.0078 0.0064
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0015 0.0132 0.0119
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0281 0.1099
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0107 0.0383
Brugia malayi hypothetical protein 0.0015 0.0132 0.0401
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0259 0.0914
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0184 0.017
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0015 0.0132 0.0487
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1261 0.1249
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0184 0.0701
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0014 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0281 0.1099
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0171 0.0275
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0015 0.0132 0.0139
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0107 0.0115
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0034 0.002
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.2442 1
Brugia malayi hypothetical protein 0.0026 0.0281 0.0904
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0107 0.0383
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.2442 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0132 0.0119
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0131 0.1801 0.179
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0133 0.1835 0.7516
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0259 0.0914
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Leishmania major hypothetical protein, conserved 0.0026 0.0281 0.1099
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.0841 0.3406
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0131 0.1801 0.179
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0015 0.0132 0.0119
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0132 0.0119
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0358 0.0344
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0078 0.0064
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Echinococcus granulosus GPCR family 2 0.0015 0.0135 0.0121
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0184 0.02
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Brugia malayi Pre-SET motif family protein 0.0031 0.0358 0.1166
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Onchocerca volvulus 0.0015 0.0132 0.0351
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0132 0.0119
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.2442 0.2856
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.0841 0.3406
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0014 0.0058
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0064 0.0841 0.3406
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) hypothetical protein 0.0031 0.0358 0.1166
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0192 0.2692 0.3146
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0841 0.3406
Schistosoma mansoni hypothetical protein 0.0033 0.0393 0.0379
Loa Loa (eye worm) hypothetical protein 0.0018 0.0171 0.0533
Onchocerca volvulus 0.0015 0.0132 0.0351
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0482 0.0469
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0089 0.1195 0.4893
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0175 0.2442 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0089 0.1195 0.4893
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0089 0.1195 0.4893
Schistosoma mansoni hypothetical protein 0.0015 0.0135 0.0121
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0015 0.0132 0.0139
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0358 0.1417
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0192 0.2692 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0131 0.1801 0.179
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0132 0.0119
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.2442 0.2431
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0132 0.0119
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0014 0.0058
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0107 0.0093
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0184 0.017
Onchocerca volvulus 0.0015 0.0132 0.0351
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0259 0.0914
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0107 0.0383
Loa Loa (eye worm) glutathione reductase 0.0039 0.0475 0.1561
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0034 0.002
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.0841 0.3406
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0259 0.1008
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0107 0.0383
Schistosoma mansoni hypothetical protein 0.0015 0.0135 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.01 0.0353
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0015 0.0132 0.0119
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0358 0.0344
Plasmodium falciparum glutathione reductase 0.0039 0.0475 0.1897
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0015 0.0132 0.0401
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0015 0.0132 0.0119
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0157 0.0644
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Brugia malayi hypothetical protein 0.0016 0.015 0.0461
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0184 0.0701
Onchocerca volvulus 0.0015 0.0132 0.0351
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0259 0.1008
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0184 0.0755
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0192 0.2692 0.9079
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0281 0.1099
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Echinococcus multilocularis 0.0015 0.0132 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0034 0.002
Schistosoma mansoni hypothetical protein 0.0015 0.0135 0.0121
Loa Loa (eye worm) hypothetical protein 0.0019 0.0184 0.0577
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0015 0.0132 0.0401
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0358 0.0344
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.5992 0.5986
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0107 0.0383
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0841 0.3406
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0107 0.0439
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0107 0.0383
Mycobacterium ulcerans phosphoglycerate kinase 0.0175 0.2442 0.9065
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0259 0.1008
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0259 0.0914
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0157 0.0644
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0015 0.0132 0.0139
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0034 0.002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0259 0.0288
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0259 0.0288
Loa Loa (eye worm) hypothetical protein 0.0015 0.0135 0.0409
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0259 0.0914
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0135 0.0121
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Echinococcus granulosus phosphoglycerate kinase 1 0.0175 0.2442 0.2431
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0015 0.0132 0.0119
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0015 0.0132 0.0487
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0615 0.2036
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0135 0.0121
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0107 0.0383
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0259 0.1008
Brugia malayi Protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Echinococcus granulosus cpg binding protein 0.0031 0.0364 0.035
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0131 0.1801 0.6059
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0281 0.1099
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.01 0.0353
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.1338 0.5479
Loa Loa (eye worm) hypothetical protein 0.0049 0.0615 0.2036
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0259 0.083
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0132 0.0119
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0107 0.0093
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) hypothetical protein 0.0018 0.0171 0.0533
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0132 0.0119
Schistosoma mansoni cpg binding protein 0.003 0.0339 0.0326
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0015 0.0132 0.0401
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0281 0.1099
Onchocerca volvulus 0.0015 0.0132 0.0351
Brugia malayi hypothetical protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0184 0.0701
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Plasmodium vivax glutathione reductase, putative 0.0039 0.0475 0.1897
Echinococcus multilocularis GPCR, family 2 0.0015 0.0135 0.0121
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0358 0.0344
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0192 0.2692 0.315
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0014 0.0006
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0475 0.1897
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0015 0.0132 0.0487
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0175 0.2442 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0184 0.0701
Schistosoma mansoni microtubule-associated protein tau 0.0698 1 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0184 0.0577
Onchocerca volvulus 0.0024 0.0259 0.0726
Giardia lamblia Phosphoglycerate kinase 0.0175 0.2442 0.9031
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0132 0.0119
Onchocerca volvulus 0.0031 0.0358 0.1021
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Schistosoma mansoni cpg binding protein 0.0031 0.0364 0.035
Giardia lamblia Protein tyrosine phosphatase 0.0015 0.0132 0.0098
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0184 0.0577
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0089 0.1195 0.4893
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0014 0.0058
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0339 0.1102
Loa Loa (eye worm) hypothetical protein 0.0175 0.2442 0.823
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Trypanosoma brucei phosphoglycerate kinase, putative 0.0064 0.0841 0.3406
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0015 0.0132 0.0119
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0171 0.0648
Entamoeba histolytica phosphoglycerate kinase, putative 0.0175 0.2442 0.2851
Trichomonas vaginalis set domain proteins, putative 0.024 0.3384 0.3962
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0015 0.0132 0.0119
Trypanosoma brucei unspecified product 0.0013 0.01 0.0353
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Onchocerca volvulus 0.0015 0.0132 0.0351
Echinococcus multilocularis hypothetical protein 0.0015 0.0132 0.0119
Brugia malayi Thioredoxin reductase 0.0039 0.0475 0.1561
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Plasmodium vivax SET domain protein, putative 0.0031 0.0358 0.1417
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0107 0.0093
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0014 0.0058
Schistosoma mansoni hypothetical protein 0.0015 0.0135 0.0121
Schistosoma mansoni DNA polymerase eta 0.0019 0.0184 0.017
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0259 0.0914
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0769 0.3111
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0184 0.0577
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0015 0.0132 0.0401
Onchocerca volvulus 0.0015 0.0132 0.0351
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Giardia lamblia DINP protein human, muc B family 0.0019 0.0184 0.0298
Leishmania major tyrosine specific protein phosphatase, putative 0.0015 0.0132 0.0487
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0034 0.002
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0192 0.2692 0.315
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0259 0.083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1261 0.1249
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.006 0.0046
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.2442 0.2431
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.1261 0.1249
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0281 0.1099
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0089 0.1195 0.4863
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.0475 0.1897
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0059 0.0151
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0015 0.0132 0.0401
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0014 0.0058
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0014 0.0058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Onchocerca volvulus 0.0015 0.0132 0.0351
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0259 0.106
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0184 0.0206
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0078 0.0064
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0015 0.0132 0.0487
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0015 0.0132 0.0119
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0135 0.0409
Brugia malayi CXXC zinc finger family protein 0.003 0.0339 0.1102
Plasmodium falciparum thioredoxin reductase 0.0013 0.0107 0.0383
Brugia malayi Phosphoglycerate kinase 0.0175 0.2442 0.823
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.0475 0.1944
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0192 0.2692 0.315
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0132 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0358 0.0344
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0184 0.017
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0132 0.0119
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma brucei unspecified product 0.0019 0.0184 0.0701
Onchocerca volvulus 0.0015 0.0132 0.0351
Leishmania major phosphoglycerate kinase C, glycosomal 0.0175 0.2442 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0184 0.0755
Onchocerca volvulus 0.0015 0.0132 0.0351
Mycobacterium tuberculosis Probable dehydrogenase 0.0089 0.1195 0.4893
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0259 0.0288
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0615 0.2036
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.0107 0.0347
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0184 0.0206
Leishmania major DNA polymerase eta, putative 0.0019 0.0184 0.0701
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.0107 0.0347
Trypanosoma brucei phosphoglycerate kinase 0.0064 0.0841 0.3406
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0192 0.2692 1
Onchocerca volvulus 0.024 0.3384 1
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0769 0.3111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0157 0.0644
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0192 0.2692 0.315
Echinococcus granulosus dna polymerase kappa 0.0019 0.0184 0.017
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0171 0.0702
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0259 0.1008
Onchocerca volvulus 4.1 G protein, putative homolog 0.0015 0.0132 0.0351
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0135 0.0121
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0015 0.0132 0.0119
Leishmania major hypothetical protein, conserved 0.0059 0.0769 0.3111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0157 0.0644
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0015 0.0132 0.0119
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0015 0.0132 0.0119
Echinococcus granulosus dnaJ subfamily B 0.0421 0.5992 0.5986
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0132 0.0119
Echinococcus multilocularis microtubule associated protein 2 0.0698 1 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Treponema pallidum phosphoglycerate kinase 0.0175 0.2442 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0184 0.017
Trypanosoma brucei unspecified product 0.0013 0.01 0.0353
Echinococcus granulosus dna polymerase eta 0.0019 0.0184 0.017
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0014 0.0058
Mycobacterium tuberculosis Probable reductase 0.0089 0.1195 0.4893
Onchocerca volvulus 0.0015 0.0132 0.0351
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.1261 0.4226
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Brugia malayi hypothetical protein 0.0015 0.0132 0.0401
Schistosoma mansoni pcd6 interacting protein-related 0.0015 0.0132 0.0119
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0099 0.1338 0.5453
Onchocerca volvulus 0.0015 0.0132 0.0351
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0259 0.106
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.0475 0.1561
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0107 0.0383
Schistosoma mansoni cpg binding protein 0.0031 0.0364 0.035
Echinococcus multilocularis cpg binding protein 0.0031 0.0364 0.035
Chlamydia trachomatis phosphoglycerate kinase 0.0175 0.2442 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Toxoplasma gondii thioredoxin reductase 0.0039 0.0475 0.1897
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0333 0.0319
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.0107 0.0347
Onchocerca volvulus 0.0192 0.2692 0.7947
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0131 0.1801 0.179
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0131 0.1801 0.179
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0014 0.0058
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0184 0.0701
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0015 0.0132 0.0119
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0192 0.2692 0.9079
Brugia malayi glutathione reductase 0.0039 0.0475 0.1561
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0393 0.1283
Trichomonas vaginalis pten, drome, putative 0.0015 0.0132 0.0145
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0099 0.1338 0.5479
Onchocerca volvulus 0.0015 0.0132 0.0351
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0015 0.0132 0.0119
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0596 0.8528 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0184 0.017
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.2442 1
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0015 0.0132 0.0119
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Brugia malayi Protein-tyrosine phosphatase 1 0.0015 0.0132 0.0401
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0132 0.0119
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0015 0.0132 0.0119
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0171 0.0648
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Plasmodium vivax phosphoglycerate kinase, putative 0.0175 0.2442 1
Plasmodium falciparum phosphoglycerate kinase 0.0175 0.2442 1
Onchocerca volvulus 0.0015 0.0132 0.0351
Onchocerca volvulus 0.0015 0.0132 0.0351
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0059 0.0769 0.3111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0171 0.0533
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0132 0.0119
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0184 0.0701
Loa Loa (eye worm) hypothetical protein 0.0018 0.0171 0.0533
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0135 0.0409
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0014 0.0058
Loa Loa (eye worm) histone methyltransferase 0.001 0.006 0.0157
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0107 0.0383
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0737 0.2978
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0107 0.0383
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.006 0.0046
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0015 0.0132 0.0119
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0132 0.0401
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0055 0.014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.1261 0.1249
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0615 0.2036
Brugia malayi hypothetical protein 0.0015 0.0132 0.0401
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0184 0.0701
Loa Loa (eye worm) hypothetical protein 0.0015 0.0132 0.0401
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0132 0.0119
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0055 0.014
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.2442 0.2856
Brugia malayi Protein-tyrosine phosphatase 0.0015 0.0132 0.0401
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.01 0.0353
Brugia malayi hypothetical protein 0.0015 0.0132 0.0401
Echinococcus granulosus protein tyrosine phosphatase n9 0.0015 0.0132 0.0119
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.2964 1
Leishmania major phosphoglycerate kinase B, cytosolic 0.0175 0.2442 1
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0014 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.1261 0.1249
Echinococcus multilocularis dna polymerase eta 0.0019 0.0184 0.017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0358 0.0344
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0059 0.0769 0.0892
Trypanosoma brucei trypanothione reductase 0.0039 0.0475 0.1897
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0059 0.0769 0.0892
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0259 0.0914

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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