Detailed information for compound 760589

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.558 | Formula: C23H36N4O2
  • H donors: 0 H acceptors: 3 LogP: 2.73 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCC(=O)N1CCCC(C1)CCC(=O)N1CCN(CC1)c1ccccn1)C
  • InChi: 1S/C23H36N4O2/c1-19(2)8-10-23(29)27-13-5-6-20(18-27)9-11-22(28)26-16-14-25(15-17-26)21-7-3-4-12-24-21/h3-4,7,12,19-20H,5-6,8-11,13-18H2,1-2H3
  • InChiKey: ORVBNNYOKVLFFF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0057 0.0007
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0224 0.15 0.1454
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1936 0.3995
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0687 0.4766 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0194 0.129
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0173 0.1145 1
Schistosoma mansoni smad 0.0017 0.0044 0.0092
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0095 0.0089
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0173 0.1145 0.2347
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.093 0.1893
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0057 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0219 0.0351
Trichomonas vaginalis penicillin-binding protein, putative 0.0224 0.15 0.307
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0687 0.4766 1
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1244 0.2526
Brugia malayi MH1 domain containing protein 0.0017 0.0044 0.0021
Leishmania major hypothetical protein, conserved 0.0224 0.15 0.307
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0687 0.4766 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0219 0.0351
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0057 0.0007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0044 0.0066
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0619 0.1236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0095 0.0109
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0173 0.1145 0.2402
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0057 0.0007
Loa Loa (eye worm) acetyltransferase 0.0143 0.093 0.1876
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1936 0.3995
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0057 0.0007
Brugia malayi hypothetical protein 0.0035 0.0171 0.029
Schistosoma mansoni DNA polymerase eta 0.0019 0.0057 0.0119
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0194 0.0299
Loa Loa (eye worm) hypothetical protein 0.0324 0.2209 0.4585
Echinococcus multilocularis smad 0.0017 0.0044 0.0066
Brugia malayi MH2 domain containing protein 0.0017 0.0044 0.0021
Onchocerca volvulus 0.0224 0.15 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0057 0.0007
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0057 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1936 0.3995
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0173 0.1145 1
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0687 0.4766 1
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0173 0.1145 0.1097
Schistosoma mansoni trans-prenyltransferase 0.0173 0.1145 0.2402
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0057 0.0119
Loa Loa (eye worm) hypothetical protein 0.0324 0.2209 0.4585
Brugia malayi beta-lactamase 0.0224 0.15 0.3098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0619 0.1299
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0619 0.1299
Trypanosoma brucei hypothetical protein, conserved 0.0224 0.15 0.3125
Treponema pallidum octaprenyl-diphosphate synthase 0.0173 0.1145 1
Loa Loa (eye worm) transcription factor SMAD2 0.0252 0.1704 0.3515
Schistosoma mansoni ap endonuclease 0.0019 0.0053 0.0112
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0095 0.0089
Echinococcus granulosus tumor protein p63 0.0333 0.227 0.4763
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0173 0.1145 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0171 0.0258
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0171 0.0359
Brugia malayi MH2 domain containing protein 0.0252 0.1704 0.3528
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0687 0.4766 1
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0173 0.1145 0.2402
Loa Loa (eye worm) hypothetical protein 0.0049 0.0266 0.0471
Trypanosoma brucei unspecified product 0.0019 0.0057 0.0088
Brugia malayi Polyprenyl synthetase family protein 0.0687 0.4766 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0044 0.0092
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0057 0.0085
Leishmania major farnesyl pyrophosphate synthase 0.0687 0.4766 1
Onchocerca volvulus 0.0224 0.15 1
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1244 0.2526
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0057 0.0048
Mycobacterium tuberculosis Conserved protein 0.0224 0.15 0.1454
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0687 0.4766 1
Brugia malayi MH1 domain containing protein 0.0017 0.0044 0.0021
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0173 0.1145 0.2316
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0619 0.1218
Echinococcus multilocularis muscleblind protein 0.0324 0.2209 0.3329
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0266 0.0559
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0173 0.1145 0.2316
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0053 0.008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0619 0.1299
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0687 0.4766 1
Brugia malayi beta-lactamase family protein 0.0224 0.15 0.3098
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0171 0.0359
Echinococcus granulosus muscleblind protein 0.0324 0.2209 0.4635
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0173 0.1145 0.1725
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0057 0.0119
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0173 0.1145 0.2331
Mycobacterium ulcerans lipase LipD 0.0224 0.15 0.307
Schistosoma mansoni smad1 5 8 and 0.0017 0.0044 0.0092
Mycobacterium ulcerans hypothetical protein 0.0224 0.15 0.307
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0224 0.15 0.3147
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0219 0.0459
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1244 0.2526
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0619 0.0933
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0173 0.1145 0.2316
Entamoeba histolytica hypothetical protein 0.0035 0.0171 0.1081
Echinococcus multilocularis muscleblind protein 1 0.0324 0.2209 0.3329
Mycobacterium tuberculosis Probable esterase LipL 0.0224 0.15 0.1454
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0901 0.1891
Mycobacterium tuberculosis Probable hydrolase 0.0224 0.15 0.1454
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0173 0.1145 0.1725
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0952 0.6635 1
Mycobacterium tuberculosis Probable lipase LipE 0.0224 0.15 0.1454
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0224 0.15 0.307
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0224 0.15 0.1454
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.15 0.307
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.093 0.1401
Echinococcus multilocularis tumor protein p63 0.0333 0.227 0.3421
Schistosoma mansoni hypothetical protein 0.0035 0.0171 0.0359
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0095 0.0089
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0053 0.0041
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0687 0.4766 1
Leishmania major hypothetical protein, conserved 0.0024 0.0095 0.0089
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0057 0.0007
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0095 0.0169
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.1315 0.2677
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0057 0.0088
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0173 0.1145 0.2402
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.15 0.307
Loa Loa (eye worm) hypothetical protein 0.0224 0.15 0.3083
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0057 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.15 0.307
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0173 0.1145 0.2402
Trypanosoma cruzi polyprenyl synthase, putative 0.0173 0.1145 0.2316
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0219 0.0351
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0619 0.1299
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1244 0.2526
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0619 0.1299
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0044 0.0092
Loa Loa (eye worm) polyprenyl synthetase 0.0687 0.4766 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0224 0.15 0.307
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0194 0.0299
Leishmania major DNA polymerase eta, putative 0.0019 0.0057 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0057 0.0003
Toxoplasma gondii ABC1 family protein 0.0224 0.15 0.307
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0173 0.1145 0.1725
Loa Loa (eye worm) MH2 domain-containing protein 0.0252 0.1704 0.3515
Mycobacterium leprae Probable lipase LipE 0.0224 0.15 1
Loa Loa (eye worm) polyprenyl synthetase 0.0173 0.1145 0.2331
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0173 0.1145 0.5
Brugia malayi MH2 domain containing protein 0.0017 0.0044 0.0021
Entamoeba histolytica hypothetical protein 0.0035 0.0171 0.1081
Loa Loa (eye worm) hypothetical protein 0.0224 0.15 0.3083
Mycobacterium ulcerans esterase/lipase LipP 0.0224 0.15 0.307
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0173 0.1145 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0053 0.002
Echinococcus granulosus smad 0.0017 0.0044 0.0092
Echinococcus granulosus beta LACTamase domain containing family member 0.0224 0.15 0.3147
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0057 0.0088
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0053 0.0112
Mycobacterium leprae conserved hypothetical protein 0.0224 0.15 1
Brugia malayi Muscleblind-like protein 0.0324 0.2209 0.4597
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1936 0.3995
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0687 0.4766 0.4738
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0687 0.4766 0.7182
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0057 0.0007
Leishmania major DNA polymerase kappa, putative 0.0019 0.0057 0.0007
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0285 0.1936 0.4019
Mycobacterium ulcerans beta-lactamase 0.0224 0.15 0.307
Loa Loa (eye worm) hypothetical protein 0.0224 0.15 0.3083
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.15 0.307
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0619 0.0933
Mycobacterium tuberculosis Conserved protein 0.0224 0.15 0.1454
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.1315 0.2677
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Loa Loa (eye worm) beta-lactamase 0.0224 0.15 0.3083
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0173 0.1145 1
Entamoeba histolytica hypothetical protein 0.0035 0.0171 0.1081
Schistosoma mansoni smad1 5 8 and 0.0017 0.0044 0.0092
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0687 0.4766 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Mycobacterium tuberculosis Conserved protein 0.0224 0.15 0.1454
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0057 0.0003
Echinococcus multilocularis Smad4 0.0017 0.0044 0.0066
Brugia malayi beta-lactamase family protein 0.0224 0.15 0.3098
Trichomonas vaginalis esterase, putative 0.0224 0.15 0.307
Brugia malayi Polyprenyl synthetase family protein 0.0173 0.1145 0.2347
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0095 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1936 0.3995
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Onchocerca volvulus 0.0224 0.15 1
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1244 0.2526
Onchocerca volvulus Glucosylceramidase homolog 0.0187 0.1244 0.7922
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0285 0.1936 0.4007
Loa Loa (eye worm) hypothetical protein 0.0224 0.15 0.3083
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1244 0.2526
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0219 0.0351
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0687 0.4766 1
Trypanosoma cruzi polyprenyl synthase, putative 0.0173 0.1145 0.2316
Echinococcus granulosus dna polymerase kappa 0.0019 0.0057 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0057 0.0027
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0173 0.1145 0.1097
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0173 0.1145 0.2316
Leishmania major polyprenyl synthase, putative 0.0173 0.1145 0.2316
Giardia lamblia Farnesyl diphosphate synthase 0.0687 0.4766 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0219 0.0351
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0173 0.1145 0.2316
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0687 0.4766 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0057 0.0048
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0057 0.0007
Schistosoma mansoni Smad4 0.0017 0.0044 0.0092
Loa Loa (eye worm) hypothetical protein 0.0224 0.15 0.3083
Schistosoma mansoni ap endonuclease 0.0019 0.0053 0.0112
Schistosoma mansoni smad1 5 8 and 0.0017 0.0044 0.0092
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0095 0.0089
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0224 0.15 0.3098
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0057 0.0119
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0173 0.1145 0.2316
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Schistosoma mansoni glutathione synthetase 0.0173 0.1145 0.2402
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0057 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0057 0.0088
Plasmodium vivax hypothetical protein, conserved 0.0224 0.15 0.307
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0173 0.1145 0.2378
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0224 0.15 0.3083
Echinococcus granulosus dna polymerase eta 0.0019 0.0057 0.0119
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0687 0.4766 1
Brugia malayi Smad1 0.0017 0.0044 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.15 0.307
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0057 0.0088
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0053 0.008
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0057 0.0088
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0173 0.1145 0.2316
Leishmania major solanesyl-diphosphate synthase, putative 0.0173 0.1145 0.2316
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1936 0.3995
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0173 0.1145 0.2316
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.093 0.1951
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0224 0.15 0.3147
Entamoeba histolytica hypothetical protein 0.0035 0.0171 0.1081
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0095 0.0089
Giardia lamblia DINP protein human, muc B family 0.0019 0.0057 0.0007
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0044 0.0066
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1244 0.2526
Echinococcus granulosus Smad4 0.0017 0.0044 0.0092
Echinococcus multilocularis beta LACTamase domain containing family member 0.0224 0.15 0.226
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0224 0.15 0.1454
Echinococcus multilocularis dna polymerase eta 0.0019 0.0057 0.0085
Mycobacterium tuberculosis Probable lipase LipD 0.0224 0.15 0.1454
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0044 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0027
Loa Loa (eye worm) hypothetical protein 0.0224 0.15 0.3083
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0687 0.4766 1
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0173 0.1145 0.1097
Brugia malayi hypothetical protein 0.0024 0.0095 0.0129

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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