Detailed information for compound 772098

Basic information

Technical information
  • TDR Targets ID: 772098
  • Name: N-[4-[(2,4-dimethylphenyl)sulfamoyl]phenyl]ac etamide
  • MW: 318.391 | Formula: C16H18N2O3S
  • H donors: 2 H acceptors: 3 LogP: 2.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1C)C
  • InChi: 1S/C16H18N2O3S/c1-11-4-9-16(12(2)10-11)18-22(20,21)15-7-5-14(6-8-15)17-13(3)19/h4-10,18H,1-3H3,(H,17,19)
  • InChiKey: JZHCOUFPMGVOOC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[(2,4-dimethylphenyl)sulfamoyl]phenyl]ethanamide
  • BAS 02209153
  • N-[4-(2,4-Dimethyl-phenylsulfamoyl)-phenyl]-acetamide
  • EU-0044994
  • ZINC00304466
  • Benzenesulfonamide, 4-acetylamino-N-(2,4-dimethylphenyl)-
  • A0757/0035372
  • AN-329/40118629
  • ARONIS022466

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni biogenic amine receptor 0.0045 0.0488 0.1595
Onchocerca volvulus Huntingtin homolog 0.0119 0.206 1
Echinococcus granulosus g-protein coupled receptor 0.0045 0.0488 0.0483
Echinococcus granulosus zinc finger protein 0.0024 0.0042 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0926 0.3043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Onchocerca volvulus 0.0045 0.0488 0.2349
Onchocerca volvulus 0.0045 0.0488 0.2349
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Onchocerca volvulus 0.0045 0.0488 0.2349
Loa Loa (eye worm) hypothetical protein 0.0119 0.206 0.6701
Loa Loa (eye worm) oxidoreductase 0.0062 0.0834 0.2712
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0045 0.0488 0.1573
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0045 0.0488 0.1595
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0488 0.0483
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Brugia malayi Bromodomain containing protein 0.0043 0.0449 0.1446
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0091 0.1454 0.4788
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Giardia lamblia Aldose reductase 0.0062 0.0834 0.6214
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0314 0.0005
Loa Loa (eye worm) oxidoreductase 0.0062 0.0834 0.2712
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0071 0.1028 0.3343
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni amine GPCR 0.0045 0.0488 0.1595
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0066 0.0926 0.0921
Brugia malayi Glycosyl hydrolases family 31 protein 0.0167 0.3075 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0045 0.0488 0.0483
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.0067 0.0943 0.8326
Loa Loa (eye worm) hypothetical protein 0.0033 0.0232 0.0754
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0488 0.0483
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0314 0.1463
Leishmania major N-myristoyl transferase, putative 0.0076 0.1132 1
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Onchocerca volvulus 0.0062 0.0834 0.4032
Echinococcus multilocularis aldo keto reductase 0.0062 0.0834 0.0829
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Leishmania major adenylate kinase, putative 0.0044 0.046 0.4035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0488 0.1595
Echinococcus granulosus choline O acetyltransferase 0.0094 0.153 0.1525
Echinococcus multilocularis geminin 0.0165 0.3031 0.3027
Entamoeba histolytica PH domain containing protein kinase, putative 0.0066 0.0926 0.7851
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0926 0.0921
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Onchocerca volvulus 0.0045 0.0488 0.2349
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0488 0.0483
Onchocerca volvulus 0.0062 0.0834 0.4032
Echinococcus granulosus aldo keto reductase 0.0062 0.0834 0.0829
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0066 0.0926 0.0921
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0081 0.1236 0.4067
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0066 0.0926 0.0921
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0067 0.0943 0.3056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Trichomonas vaginalis aldo/keto reductase, putative 0.0062 0.0834 0.6358
Echinococcus multilocularis G protein coupled receptor 139 0.0045 0.0488 0.0483
Echinococcus multilocularis aldehyde reductase 0.0044 0.0455 0.045
Trichomonas vaginalis aldo/keto reductase, putative 0.0062 0.0834 0.6358
Schistosoma mansoni bromodomain containing protein 0.0069 0.0993 0.3265
Loa Loa (eye worm) hypothetical protein 0.0062 0.0834 0.2712
Loa Loa (eye worm) hypothetical protein 0.0119 0.206 0.6701
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0314 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0314 0.0005
Echinococcus granulosus glycylpeptide N tetradecanoyltransferase 0.0076 0.1132 0.1127
Echinococcus multilocularis orexin receptor type 2 0.0045 0.0488 0.0483
Echinococcus granulosus aldo keto reductase 0.0062 0.0834 0.0829
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) melatonin receptor type 1A 0.0045 0.0488 0.1588
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0071 0.1028 0.3331
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0915 0.091
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0488 0.1595
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0314 0.0309
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0488 0.1595
Schistosoma mansoni hypothetical protein 0.0045 0.0488 0.1595
Schistosoma mansoni growth hormone secretagogue receptor 0.0045 0.0488 0.1595
Trichomonas vaginalis aldo/keto reductase, putative 0.0062 0.0834 0.6358
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0045 0.0488 0.1573
Brugia malayi Dopamine receptor protein 1 0.0045 0.0488 0.1573
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0081 0.1236 0.1231
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0066 0.0926 0.8173
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0488 0.0483
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0045 0.0488 0.0483
Echinococcus multilocularis sex peptide receptor 0.0045 0.0488 0.0483
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0488 0.1595
Echinococcus granulosus G protein coupled receptor 139 0.0045 0.0488 0.0483
Echinococcus multilocularis aldo keto reductase 0.0062 0.0834 0.0829
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0926 0.0921
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0488 0.0483
Leishmania major protein kinase A catalytic subunit 0.0066 0.0926 0.8173
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.0834 0.2699
Brugia malayi putative neuropeptide receptor NPR1 0.0045 0.0488 0.1573
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0071 0.1028 0.1023
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Brugia malayi neuropeptide F receptor 0.0045 0.0488 0.1573
Loa Loa (eye worm) CBP-B 0.0095 0.1545 0.5023
Schistosoma mansoni aldo-keto reductase 0.0062 0.0834 0.2738
Trypanosoma brucei aldo-keto reductase, putative 0.0062 0.0834 0.7355
Brugia malayi GnHR receptor homolog 0.0045 0.0488 0.1573
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0135 0.2392 0.7888
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0065 0.091 0.0905
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0062 0.0834 0.6358
Schistosoma mansoni alpha-1 adrenergic receptor 0.0045 0.0488 0.1595
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0314 0.0005
Loa Loa (eye worm) oxidoreductase 0.0062 0.0834 0.2712
Plasmodium falciparum GTP:AMP phosphotransferase 0.0044 0.046 0.2984
Onchocerca volvulus 0.0045 0.0488 0.2349
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0045 0.0488 0.1595
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0018 0.0042
Schistosoma mansoni neuropeptide receptor 0.0045 0.0488 0.1595
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Loa Loa (eye worm) hypothetical protein 0.0067 0.0943 0.3068
Giardia lamblia Aldose reductase 0.0062 0.0834 0.6214
Brugia malayi Melatonin receptor type 1A 0.0045 0.0488 0.1573
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.0067 0.0943 0.0938
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0488 0.0483
Loa Loa (eye worm) hypothetical protein 0.0094 0.153 0.4977
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0045 0.0488 0.1595
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0488 0.0483
Brugia malayi neuropeptide F receptor 0.0045 0.0488 0.1573
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Onchocerca volvulus 0.0097 0.1579 0.7658
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0488 0.1588
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0558 0.18
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus granulosus tachykinin peptides receptor 99D 0.0045 0.0488 0.0483
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0488 0.0483
Echinococcus granulosus serotonin receptor 0.0045 0.0488 0.0483
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Mycobacterium ulcerans naphthoate synthase 0.0376 0.7505 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0045 0.0488 0.1595
Echinococcus granulosus sex peptide receptor 0.0045 0.0488 0.0483
Loa Loa (eye worm) AGC/PKA protein kinase 0.0066 0.0926 0.3012
Trypanosoma brucei glucosidase, putative 0.0037 0.0314 0.2742
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0314 0.1022
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0926 0.0921
Entamoeba histolytica PH domain containing protein kinase, putative 0.0066 0.0926 0.7851
Leishmania major protein kinase A catalytic subunit isoform 2 0.0066 0.0926 0.8173
Schistosoma mansoni adenoreceptor 0.0045 0.0488 0.1595
Schistosoma mansoni choline o-acyltransferase 0.0094 0.153 0.504
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0488 0.1588
Echinococcus multilocularis choline O acetyltransferase 0.0094 0.153 0.1525
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni amine GPCR 0.0045 0.0488 0.1595
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0081 0.1236 0.1231
Entamoeba histolytica glycylpeptide N-tetradecanoyltransferase, putative 0.0076 0.1132 1
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Loa Loa (eye worm) hypothetical protein 0.0061 0.0829 0.2697
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.3075 0.3071
Brugia malayi Dopamine receptor protein 2 0.0045 0.0488 0.1573
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0045 0.0488 0.0483
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0081 0.1236 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Trypanosoma brucei N-myristoyl transferase, putative 0.0076 0.1132 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0066 0.0926 0.3012
Schistosoma mansoni amine GPCR 0.0045 0.0488 0.1595
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0045 0.0488 0.1595
Trichomonas vaginalis N-myristoyl transferase, putative 0.005 0.0581 0.3271
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0314 0.2742
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Entamoeba histolytica aldose reductase, putative 0.0062 0.0834 0.6889
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Brugia malayi N-myristoyltransferase 2 0.0076 0.1132 0.367
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0045 0.0488 0.0483
Loa Loa (eye worm) acetyltransferase 0.0091 0.1454 0.4729
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0066 0.0926 0.6639
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Trypanosoma cruzi aldo/keto reductase, putative 0.0062 0.0834 0.7355
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0062 0.0834 0.7355
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus granulosus g protein coupled receptor 0.0045 0.0488 0.0483
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0081 0.1236 0.1231
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.0023 0.0005 0.0018
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Echinococcus granulosus neuropeptide FF receptor 2 0.0045 0.0488 0.0483
Echinococcus multilocularis glycylpeptide N tetradecanoyltransferase 0.0076 0.1132 0.1127
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0045 0.0488 0.1588
Brugia malayi ORL1-like opioid receptor 0.0045 0.0488 0.1573
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Brugia malayi AKH receptor 0.0045 0.0488 0.1573
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0488 0.0483
Loa Loa (eye worm) hypothetical protein 0.0049 0.0558 0.1815
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0488 0.1588
Echinococcus multilocularis neuropeptide s receptor 0.0493 1 1
Schistosoma mansoni alpha glucosidase 0.0037 0.0314 0.1021
Schistosoma mansoni myosin xvIII 0.0045 0.0488 0.1595
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0488 0.0483
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0066 0.0926 0.8173
Schistosoma mansoni alpha-glucosidase 0.0144 0.2581 0.8512
Schistosoma mansoni amine GPCR 0.0045 0.0488 0.1595
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Leishmania major protein kinase A catalytic subunit isoform 1 0.0066 0.0926 0.8173
Trypanosoma cruzi N-myristoyl transferase, putative 0.0076 0.1132 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0488 0.0483
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0062 0.0834 0.0537
Echinococcus multilocularis dro:myosuppressin receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0488 0.0483
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Brugia malayi TAZ zinc finger family protein 0.0135 0.2392 0.7775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0488 0.1595
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0488 0.0483
Brugia malayi G-protein coupled receptor 0.0045 0.0488 0.1573
Giardia lamblia Kinase, AGC PKA 0.0066 0.0926 0.7081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0066 0.0926 0.8173
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni alpha-glucosidase 0.0144 0.2581 0.8512
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0045 0.0488 0.1588
Onchocerca volvulus 0.0045 0.0488 0.2349
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0314 0.1006
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0066 0.0926 0.8173
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0066 0.0926 0.8173
Loa Loa (eye worm) N-myristoyltransferase 2 0.0076 0.1132 0.3681
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0081 0.1236 0.1231
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Brugia malayi G-protein coupled receptor 0.0045 0.0488 0.1573
Loa Loa (eye worm) hypothetical protein 0.0048 0.0544 0.1769
Onchocerca volvulus 0.0062 0.0834 0.4032
Onchocerca volvulus 0.0045 0.0488 0.2349
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0232 0.0737
Echinococcus granulosus g protein coupled receptor 0.0045 0.0488 0.0483
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0488 0.0483
Echinococcus granulosus CREB binding protein 0.0085 0.1329 0.1324
Echinococcus multilocularis neuropeptide FF receptor 2 0.0045 0.0488 0.0483
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0926 0.7484
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.3075 0.3071
Schistosoma mansoni histamine h1 receptor 0.0045 0.0488 0.1595
Loa Loa (eye worm) choline O-acetyltransferase 0.0094 0.153 0.4977
Loa Loa (eye worm) hypothetical protein 0.0066 0.0926 0.3012
Schistosoma mansoni neuropeptide f receptor 76f 0.0045 0.0488 0.1595
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0066 0.0926 0.7484
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0045 0.0488 0.1573
Echinococcus multilocularis G-protein coupled receptor, putative 0.0045 0.0488 0.0483
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.0834 0.2699
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus granulosus dro:myosuppressin receptor 0.0045 0.0488 0.0483
Brugia malayi Choline O-acetyltransferase 0.0094 0.153 0.4968
Brugia malayi G protein-coupled receptor F59B2.13 0.0045 0.0488 0.1573
Brugia malayi Serotonin receptor 0.0045 0.0488 0.1573
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0066 0.0926 0.7851
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0488 0.0483
Schistosoma mansoni CREB-binding protein 2 0.0135 0.2392 0.7888
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0488 0.0483
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0488 0.0483
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0488 0.1588
Echinococcus granulosus geminin 0.0165 0.3031 0.3027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Brugia malayi acetyltransferase, GNAT family protein 0.0091 0.1454 0.4719
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni hypothetical protein 0.0045 0.0488 0.1595
Brugia malayi larval opioid receptor 0.0045 0.0488 0.1573
Toxoplasma gondii AGC kinase 0.0066 0.0926 0.6639
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0045 0.0488 0.1595
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0045 0.0488 0.2349
Echinococcus granulosus aldehyde reductase 0.0044 0.0455 0.045
Echinococcus granulosus CREB binding protein 0.0135 0.2392 0.2388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Leishmania major prostaglandin f synthase, putative 0.0062 0.0834 0.7355
Echinococcus granulosus hypothetical protein 0.0045 0.0488 0.0483
Schistosoma mansoni hypothetical protein 0.0045 0.0488 0.1595
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0488 0.0483
Trypanosoma brucei prostaglandin f synthase 0.0062 0.0834 0.7355
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0558 0.18
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0314 0.0005
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0062 0.0834 0.6358
Loa Loa (eye worm) hypothetical protein 0.0046 0.0502 0.1634
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0062 0.0834 0.7355
Schistosoma mansoni hypothetical protein 0.0045 0.0488 0.1595
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Echinococcus multilocularis aldo keto reductase 0.0062 0.0834 0.0829
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0488 0.1595
Echinococcus granulosus aldo keto reductase 0.0062 0.0834 0.0829
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0066 0.0926 0.2999
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0314 0.0005
Brugia malayi G protein-coupled receptor 0.0045 0.0488 0.1573
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni neuropeptide receptor 0.0045 0.0488 0.1595
Brugia malayi sulfakinin receptor protein 0.0045 0.0488 0.1573
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.0023 0.0005 0.0018
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0018 0.0013
Echinococcus granulosus neuropeptide receptor A26 0.0493 1 1
Onchocerca volvulus 0.0062 0.0834 0.4032
Echinococcus granulosus orexin receptor type 2 0.0045 0.0488 0.0483
Onchocerca volvulus Huntingtin homolog 0.0119 0.206 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0071 0.1028 0.1023
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0926 0.3043
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Brugia malayi Serotonin receptor 0.0045 0.0488 0.1573
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0488 0.0483
Loa Loa (eye worm) oxidoreductase 0.0062 0.0834 0.2712
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Brugia malayi putative neuropeptide receptor 0.0045 0.0488 0.1573
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0488 0.0483
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0926 0.3043
Schistosoma mansoni N-myristoyltransferase 0.0076 0.1132 0.3723
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0488 0.1595
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0314 0.0005
Echinococcus granulosus hypothetical protein 0.0062 0.0834 0.0829
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0045 0.0488 0.0483
Giardia lamblia CDC72 0.0076 0.1132 0.9019
Echinococcus multilocularis g-protein coupled receptor 0.0045 0.0488 0.0483
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0045 0.0488 0.1588
Schistosoma mansoni pol-related 0.0062 0.0834 0.2738
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis aldo keto reductase 0.0062 0.0834 0.0829
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0045 0.0488 0.1595
Schistosoma mansoni aldo-keto reductase 0.0062 0.0834 0.2738
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0314 0.0309
Schistosoma mansoni hypothetical protein 0.0033 0.0232 0.0748
Schistosoma mansoni opsin-like receptor 0.0045 0.0488 0.1595
Mycobacterium leprae PROBABLE NAPHTHOATE SYNTHASE MENB (DIHYDROXYNAPHTHOIC ACID SYNTHETASE) (DHNA SYNTHETASE) 0.0376 0.7505 1
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0488 0.1595
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0314 0.0005
Schistosoma mansoni opsin-like receptor 0.0045 0.0488 0.1595
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni neuropeptide receptor 0.0045 0.0488 0.1595
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0488 0.1595
Mycobacterium tuberculosis Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase) 0.0376 0.7505 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0167 0.3075 1
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0488 0.1595
Echinococcus granulosus g protein coupled receptor 0.0045 0.0488 0.0483
Entamoeba histolytica aldose reductase, putative 0.0062 0.0834 0.6889
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Schistosoma mansoni opsin-like receptor 0.0045 0.0488 0.1595
Schistosoma mansoni biogenic amine receptor 0.0045 0.0488 0.1595
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0045 0.0488 0.1595
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0488 0.0483
Schistosoma mansoni amine GPCR 0.0045 0.0488 0.1595
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0045 0.0488 0.0483
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Brugia malayi Bromodomain containing protein 0.0081 0.1248 0.405
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.031 0.0304
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Echinococcus multilocularis serotonin receptor 0.0045 0.0488 0.0483
Brugia malayi hypothetical protein 0.0119 0.206 0.6695
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0067 0.0943 0.8326
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus granulosus lysosomal alpha glucosidase 0.0167 0.3075 0.3071
Brugia malayi PHD-finger family protein 0.003 0.0158 0.0496
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0314 0.2742
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0558 0.1815
Entamoeba histolytica aldose reductase, putative 0.0062 0.0834 0.6889
Brugia malayi RE15519p 0.0045 0.0488 0.1573
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0045 0.0488 0.1588
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0926 0.0921
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.0067 0.0943 0.0938
Trypanosoma cruzi N-myristoyl transferase, putative 0.0076 0.1132 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.1236 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0045 0.0488 0.0483
Loa Loa (eye worm) hypothetical protein 0.0081 0.1236 0.402
Onchocerca volvulus 0.0045 0.0488 0.2349
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Echinococcus multilocularis CREB binding protein 0.0094 0.152 0.1516
Schistosoma mansoni hypothetical protein 0.0165 0.3031 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Brugia malayi Dopamine receptor 0.0045 0.0488 0.1573
Onchocerca volvulus 0.0062 0.0834 0.4032
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0045 0.0488 0.1573
Trichomonas vaginalis N-myristoyl transferase, putative 0.0076 0.1132 1
Schistosoma mansoni zinc finger protein 0.0024 0.0042 0.0119
Onchocerca volvulus 0.0045 0.0488 0.2349
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus granulosus histone acetyltransferase KAT2B 0.0074 0.1097 0.1092
Echinococcus granulosus allatostatin A receptor 0.0045 0.0488 0.0483
Loa Loa (eye worm) hypothetical protein 0.0039 0.0363 0.1179
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0045 0.0488 0.0483
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0314 0.0005
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.0834 0.2699
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Echinococcus multilocularis neuropeptide receptor A26 0.0493 1 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Echinococcus granulosus fmrfamide receptor 0.0045 0.0488 0.0483
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0045 0.0488 0.1588
Echinococcus granulosus 7tm_1 domain containing protein 0.0045 0.0488 0.0483
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Loa Loa (eye worm) oxidoreductase 0.0062 0.0834 0.2712
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0314 0.0005
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0066 0.0926 0.8173
Brugia malayi follicle stimulating hormone receptor 0.0045 0.0488 0.1573
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis serotonin receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis somatostatin receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.031 0.0304
Echinococcus multilocularis zinc finger protein 0.0024 0.0042 0.0036
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0091 0.1454 0.1449
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.0834 0.0829
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.0834 0.6358
Echinococcus granulosus neuropeptide receptor 0.0045 0.0488 0.0483
Brugia malayi Choline O-acetyltransferase 0.0094 0.153 0.4968
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0915 0.091
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0062 0.0834 0.6358
Echinococcus granulosus alpha 1A adrenergic receptor 0.0045 0.0488 0.0483
Echinococcus granulosus neuropeptide receptor 0.0045 0.0488 0.0483
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0314 0.2742
Loa Loa (eye worm) hypothetical protein 0.0073 0.1067 0.3471
Onchocerca volvulus 0.0062 0.0834 0.4032
Toxoplasma gondii adenylate kinase 0.0044 0.046 0.1584
Plasmodium vivax adenylate kinase 1, putative 0.0044 0.046 0.1786
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0314 0.1463
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0488 0.0483
Schistosoma mansoni neuropeptide receptor 0.0045 0.0488 0.1595
Brugia malayi Tachykinin-like peptides receptor 99D 0.0045 0.0488 0.1573
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0045 0.0488 0.0483
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.0834 0.2699
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0488 0.0483
Plasmodium vivax glycylpeptide N-tetradecanoyltransferase, putative 0.0076 0.1132 1
Onchocerca volvulus 0.0045 0.0488 0.2349
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0488 0.0483
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0067 0.0943 0.8326
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0488 0.0483
Trypanosoma brucei N-myristoyltransferase 0.0076 0.1132 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Brugia malayi hypothetical protein 0.0045 0.0488 0.1573
Echinococcus granulosus histone acetyltransferase KAT2B 0.0037 0.0314 0.0309
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Toxoplasma gondii aldose reductase, putative 0.0062 0.0834 0.564
Schistosoma mansoni hypothetical protein 0.0165 0.3031 1
Trypanosoma cruzi aldo-keto reductase 0.0062 0.0834 0.7355
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0065 0.091 0.0905
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0066 0.0926 0.8173
Leishmania major aldo-keto reductase-like protein 0.0062 0.0834 0.7355
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0045 0.0488 0.0483
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0045 0.0488 0.1573
Echinococcus multilocularis allatostatin A receptor 0.0045 0.0488 0.0483
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0488 0.0483
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Schistosoma mansoni biogenic amine receptor 0.0045 0.0488 0.1595
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0488 0.0483
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.0834 0.0829
Loa Loa (eye worm) hypothetical protein 0.0045 0.0488 0.1588
Loa Loa (eye worm) TYRA-2 protein 0.0045 0.0488 0.1588
Onchocerca volvulus Neuropeptide F receptor homolog 0.0045 0.0488 0.2349
Echinococcus granulosus somatostatin receptor 0.0045 0.0488 0.0483
Echinococcus granulosus peptide allatostatin:somatostatin 0.0045 0.0488 0.0483
Toxoplasma gondii AGC kinase 0.0066 0.0926 0.6639
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0045 0.0488 0.0483
Plasmodium falciparum glycylpeptide N-tetradecanoyltransferase 0.0076 0.1132 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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