Detailed information for compound 778002

Basic information

Technical information
  • TDR Targets ID: 778002
  • Name: 2,3-dimethoxy-6-methylindolo[3,2-b]quinoxalin e
  • MW: 293.32 | Formula: C17H15N3O2
  • H donors: 0 H acceptors: 2 LogP: 2.99 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2nc3c(nc2cc1OC)c1c(n3C)cccc1
  • InChi: 1S/C17H15N3O2/c1-20-13-7-5-4-6-10(13)16-17(20)19-12-9-15(22-3)14(21-2)8-11(12)18-16/h4-9H,1-3H3
  • InChiKey: STVLCIRWFDAYHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2,3-dimethoxy-6-methyl-indolo[3,2-b]quinoxaline
  • ZINC04513690

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi latrophilin 2 splice variant baaae 0.0079 0.1121 0.1392
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Mycobacterium ulcerans DNA gyrase subunit B 0.0173 0.2667 0.6094
Entamoeba histolytica DNA topoisomerase II, putative 0.0195 0.3024 1
Echinococcus granulosus GPCR family 2 0.0037 0.042 0.0405
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0339 0.0324
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0403 0.0936
Toxoplasma gondii ABC1 family protein 0.0036 0.0403 0.087
Brugia malayi DNA topoisomerase III 0.0014 0.0046 0.0039
Plasmodium falciparum DNA gyrase subunit A 0.0239 0.3762 0.5331
Echinococcus multilocularis pyruvate kinase 0.0017 0.0092 0.0077
Schistosoma mansoni nAChR subunit 0.0026 0.0248 0.0233
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0076 0.1063 0.3413
Echinococcus granulosus pyruvate kinase 0.0033 0.0353 0.0338
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0026 0.0248 0.0311
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0076 0.1063 0.2292
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0345 0.0789
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0548 0.0533
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0026 0.0248 0.0233
Onchocerca volvulus 0.0015 0.0056 0.0119
Mycobacterium ulcerans hypothetical protein 0.0021 0.0166 0.038
Schistosoma mansoni nAChR subunit 0.0026 0.0248 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0395 0.038
Brugia malayi Pre-SET motif family protein 0.0194 0.3016 0.3778
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0012 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0403 0.0507
Trypanosoma cruzi DNA topoisomerase II, putative 0.0181 0.2794 0.7247
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0548 0.0533
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Brugia malayi major facilitator superfamily protein 0.0015 0.0056 0.0052
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0242 0.0227
Loa Loa (eye worm) sugar transporter 0.0015 0.0056 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0064 0.002
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0057 0.0042
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0345 0.0789
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0244 0.3838 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Schistosoma mansoni DNA topoisomerase II 0.0195 0.3024 0.3014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0242 0.0227
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0153 0.233 0.6725
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0403 0.0488
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0698 0.0859
Echinococcus granulosus intermediate filament protein 0.0053 0.0698 0.0683
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0339 0.0324
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0035 0.0393 0.0913
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0548 0.0671
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0026 0.0248 0.0233
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0056 0.0041
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1522 0.1509
Loa Loa (eye worm) LGC-31 protein 0.0026 0.0248 0.0311
Onchocerca volvulus 0.0015 0.0056 0.0119
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Schistosoma mansoni cpg binding protein 0.003 0.0311 0.0296
Brugia malayi Cation transporter family protein 0.0026 0.0248 0.0292
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0014 0.0046 0.0031
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0353 0.0443
Brugia malayi CXXC zinc finger family protein 0.0028 0.0284 0.0339
Echinococcus multilocularis solute carrier family 22 0.0015 0.0056 0.0041
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0083 0.0068
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0014 0.0046 0.0106
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0353 0.0981
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0036 0.0403 0.0507
Schistosoma mansoni sugar transporter 0.0015 0.0056 0.0041
Entamoeba histolytica hypothetical protein 0.0035 0.0395 0.117
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0057 0.0027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0345 0.0789
Echinococcus multilocularis pyruvate kinase 0.0017 0.0092 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.019 0.0239
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0403 0.0921
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0092 0.0198
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0026 0.0248 0.0233
Loa Loa (eye worm) hypothetical protein 0.0025 0.0226 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0403 0.0941
Entamoeba histolytica hypothetical protein 0.0035 0.0395 0.117
Toxoplasma gondii facilitative glucose transporter GT1 0.0104 0.1522 0.3284
Leishmania major pyruvate kinase 0.0033 0.0353 0.0808
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0055 0.0718 0.0704
Schistosoma mansoni hypothetical protein 0.0035 0.0395 0.038
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0175 0.2696 0.2684
Echinococcus multilocularis musashi 0.0053 0.0698 0.0683
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0014 0.0046 0.0031
Loa Loa (eye worm) glutaminase 2 0.0277 0.4377 0.5499
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0026 0.0248 0.0233
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0167 0.2573 0.3646
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0015 0.0057 0.0071
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.015 0.0343
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0698 0.0876
Loa Loa (eye worm) hypothetical protein 0.0031 0.0328 0.0412
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0353 0.0981
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0026 0.0248 0.0233
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0403 0.0571
Schistosoma mansoni pyruvate kinase 0.0033 0.0353 0.0338
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0197 0.0279
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0057 0.0042
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0068 0.0932 0.2364
Loa Loa (eye worm) GABA receptor subunit 0.0014 0.0049 0.0061
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0056 0.0041
Onchocerca volvulus 0.0015 0.0056 0.0119
Loa Loa (eye worm) hypothetical protein 0.0016 0.0078 0.0098
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Brugia malayi excitatory GABA receptor EXP-1A 0.0026 0.0248 0.0292
Schistosoma mansoni glucose transport protein 0.0104 0.1522 0.1509
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0175 0.2696 0.3387
Loa Loa (eye worm) hypothetical protein 0.0032 0.0339 0.0426
Mycobacterium ulcerans beta-lactamase 0.0036 0.0403 0.0921
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0057 0.0071
Giardia lamblia DNA topoisomerase II 0.0185 0.2862 1
Brugia malayi Cation transporter family protein 0.0026 0.0248 0.0292
Brugia malayi Probable DNA topoisomerase II 0.0195 0.3024 0.3788
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Echinococcus multilocularis microtubule associated protein 2 0.0618 1 1
Plasmodium falciparum protein kinase 6 0.0439 0.7057 1
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0195 0.3024 0.3014
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0339 0.0731
Brugia malayi follicle stimulating hormone receptor 0.0234 0.368 0.4613
Schistosoma mansoni hypothetical protein 0.0037 0.042 0.0405
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0395 0.038
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0413 0.0967
Echinococcus granulosus glycine receptor subunit beta 0.0026 0.0248 0.0233
Plasmodium falciparum DNA gyrase subunit B 0.0173 0.2667 0.3779
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0026 0.0248 0.0233
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Echinococcus multilocularis lamin dm0 0.0053 0.0698 0.0683
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0403 0.0936
Chlamydia trachomatis DNA gyrase subunit B 0.0173 0.2667 0.7053
Schistosoma mansoni cpg binding protein 0.0028 0.0284 0.027
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0021 0.0166 0.038
Onchocerca volvulus 0.0026 0.0248 0.0675
Plasmodium vivax SET domain protein, putative 0.0028 0.0284 0.0403
Brugia malayi intermediate filament protein 0.0053 0.0698 0.0859
Loa Loa (eye worm) hypothetical protein 0.0015 0.0057 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0028 0.0284 0.0269
Schistosoma mansoni nAChR subunit 0.0026 0.0248 0.0233
Brugia malayi Cation transporter family protein 0.0026 0.0248 0.0292
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0166 0.038
Echinococcus granulosus inositol monophosphatase 1 0.0076 0.1063 0.1049
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0026 0.0248 0.0292
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0175 0.2696 0.2684
Loa Loa (eye worm) hypothetical protein 0.0037 0.042 0.0528
Loa Loa (eye worm) hypothetical protein 0.0036 0.0403 0.0507
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Brugia malayi hypothetical protein 0.0015 0.0056 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0284 0.0269
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0413 0.0967
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Schistosoma mansoni hypothetical protein 0.0037 0.042 0.0405
Echinococcus granulosus solute carrier family 22 0.0015 0.0056 0.0041
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0353 0.0425
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0353 0.0981
Mycobacterium ulcerans sugar transporter 0.0015 0.0056 0.0129
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0166 0.0316
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0353 0.3784
Plasmodium vivax DNA topoisomerase 3, putative 0.0014 0.0046 0.0066
Echinococcus granulosus lamin 0.0053 0.0698 0.0683
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0195 0.3024 0.3788
Schistosoma mansoni hypothetical protein 0.0079 0.1121 0.1107
Echinococcus multilocularis pyruvate kinase 0.0033 0.0353 0.0338
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0026 0.0248 0.0292
Trypanosoma brucei glucose transporter 2A 0.0032 0.0345 0.0789
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0056 0.0129
Plasmodium vivax CDK-related protein kinase 6, putative 0.0439 0.7057 1
Schistosoma mansoni sugar transporter 0.0015 0.0056 0.0041
Trichomonas vaginalis DNA topoisomerase II, putative 0.0195 0.3024 0.691
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0057 0.0042
Schistosoma mansoni nAChR subunit 0.0026 0.0248 0.0233
Mycobacterium tuberculosis Conserved protein 0.0036 0.0403 0.0936
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0057 0.0042
Schistosoma mansoni sugar transporter 0.0015 0.0056 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0064 0.002
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0057 0.0071
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0175 0.2696 0.2684
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Plasmodium vivax DNA gyrase subunit A, putative 0.0239 0.3762 0.5331
Loa Loa (eye worm) hypothetical protein 0.0079 0.1121 0.1408
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Giardia lamblia Pyruvate kinase 0.0017 0.0092 0.0161
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Echinococcus granulosus pyruvate kinase 0.0033 0.0353 0.0338
Giardia lamblia Hexose transporter 0.0015 0.0056 0.0035
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0339 0.048
Schistosoma mansoni glucose transport protein 0.0104 0.1522 0.1509
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0056 0.0129
Leishmania major hypothetical protein, conserved 0.0015 0.0056 0.0026
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0166 0.019
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1522 0.1509
Onchocerca volvulus 0.0015 0.0056 0.0119
Toxoplasma gondii DNA topoisomerase family protein 0.0014 0.0046 0.01
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0353 0.08
Onchocerca volvulus Putative nachr subunit 0.0175 0.2696 0.7788
Echinococcus multilocularis geminin 0.0272 0.4296 0.4287
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0345 0.0789
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0166 0.1784
Chlamydia trachomatis DNA gyrase subunit B 0.0124 0.1853 0.4863
Chlamydia trachomatis DNA gyrase subunit A 0.0239 0.3762 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0403 0.0507
Brugia malayi jmjC domain containing protein 0.0056 0.0744 0.0918
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0339 0.0324
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0026 0.0248 0.0311
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0239 0.3762 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0413 0.0967
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0413 0.0585
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Mycobacterium tuberculosis Conserved protein 0.0036 0.0403 0.0936
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0056 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0345 0.0789
Trypanosoma cruzi DNA topoisomerase II, putative 0.0181 0.2794 0.7247
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0026 0.0248 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0056 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Echinococcus granulosus phd:f box containing protein 0.0015 0.0057 0.0042
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0413 0.0967
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Schistosoma mansoni hypothetical protein 0.0405 0.6482 0.6477
Leishmania major protein kinase, putative 0.0032 0.0339 0.0771
Echinococcus multilocularis solute carrier family 22 0.0015 0.0056 0.0041
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0166 0.0316
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1522 0.1509
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0057 0.0122
Trypanosoma brucei sugar transporter, putative 0.0015 0.0056 0.0026
Entamoeba histolytica hypothetical protein 0.0014 0.0049 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Echinococcus granulosus solute carrier family 22 0.0015 0.0056 0.0041
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0026 0.0248 0.0233
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0166 0.0316
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0403 0.0936
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0015 0.0071 0.007
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0698 0.0876
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0339 0.0426
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0057 0.0122
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0328 0.0313
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0026 0.0248 0.0233
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Echinococcus multilocularis survival motor neuron protein 1 0.0494 0.7959 0.7956
Loa Loa (eye worm) hypothetical protein 0.0036 0.0403 0.0507
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0248 0.0292
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0345 0.0789
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0181 0.2794 0.7247
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0339 0.0731
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0328 0.0946
Trichomonas vaginalis esterase, putative 0.0036 0.0403 0.0921
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0166 0.038
Plasmodium falciparum hexose transporter 0.0104 0.1522 0.2157
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0016 0.0078 0.0098
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0153 0.233 0.6725
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0049 0.0033
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0353 0.0761
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0353 0.0425
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0056 0.0052
Schistosoma mansoni lamin 0.0053 0.0698 0.0683
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0197 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Giardia lamblia Pyruvate kinase 0.0033 0.0353 0.1088
Echinococcus granulosus pyruvate kinase 0.0017 0.0092 0.0077
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0026 0.0248 0.0233
Echinococcus granulosus solute carrier family 22 0.0015 0.0056 0.0041
Onchocerca volvulus 0.0015 0.0056 0.0119
Onchocerca volvulus 0.0015 0.0056 0.0119
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0328 0.0313
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0021 0.0162 0.0285
Brugia malayi Calcitonin receptor-like protein seb-1 0.0116 0.1725 0.2152
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.1477 0.184
Brugia malayi Sugar transporter family protein 0.0015 0.0056 0.0052
Mycobacterium ulcerans lipase LipD 0.0036 0.0403 0.0921
Schistosoma mansoni glucose transport protein 0.0104 0.1522 0.1509
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0139
Leishmania major mitochondrial DNA topoisomerase II 0.0244 0.3838 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Mycobacterium tuberculosis Conserved protein 0.0036 0.0403 0.0936
Loa Loa (eye worm) ACC-1 protein 0.0026 0.0248 0.0311
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0153 0.233 0.6725
Loa Loa (eye worm) hypothetical protein 0.0069 0.0947 0.119
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0056 0.0121
Mycobacterium ulcerans DNA gyrase subunit A 0.0239 0.3762 0.8596
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0049 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.019 0.0239
Leishmania major DNA topoisomerase ii 0.0181 0.2794 0.7247
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0195 0.3024 0.3014
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0056 0.0052
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0056 0.0041
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0248 0.0292
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Leishmania major glucose transporter, lmgt1 0.0032 0.0345 0.0789
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0056 0.0026
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.0015 0.0019
Echinococcus multilocularis General substrate transporter 0.0089 0.1282 0.1269
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0403 0.0921
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0345 0.0789
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0056 0.0026
Loa Loa (eye worm) hypothetical protein 0.0116 0.1725 0.2167
Plasmodium vivax JmjC domain containing protein 0.0015 0.0057 0.008
Schistosoma mansoni hypothetical protein 0.0101 0.1477 0.1464
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0353 0.0443
Toxoplasma gondii hypothetical protein 0.0031 0.0322 0.0694
Brugia malayi beta-lactamase 0.0036 0.0403 0.0488
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0197 0.0451
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0288 0.0362
Schistosoma mansoni nAChR subunit 0.0026 0.0248 0.0233
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0015 0.0071 0.007
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0026 0.0248 0.0311
Echinococcus multilocularis inositol monophosphatase 1 0.0076 0.1063 0.1049
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0284 0.0357
Onchocerca volvulus 0.0015 0.0056 0.0119
Echinococcus multilocularis lamin 0.0053 0.0698 0.0683
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0026 0.0248 0.0233
Loa Loa (eye worm) DNA topoisomerase III 0.0014 0.0046 0.0058
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.1063 0.2681
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0284 0.0269
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0057 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0021 0.0166 0.0297
Toxoplasma gondii sugar transporter ST3 0.0015 0.0056 0.0121
Schistosoma mansoni hypothetical protein 0.0272 0.4296 0.4287
Echinococcus granulosus lysine specific demethylase 5A 0.0056 0.0744 0.073
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0403 0.0388
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0339 0.048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0064 0.002
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0239 0.3762 0.8114
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0173 0.2667 0.7053
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0166 0.1784
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0014 0.0046 0.0106
Trypanosoma brucei DNA topoisomerase ii 0.0244 0.3838 1
Echinococcus granulosus lamin dm0 0.0053 0.0698 0.0683
Echinococcus granulosus glycine receptor subunit alpha 1 0.0026 0.0248 0.0233
Schistosoma mansoni pyruvate kinase 0.0033 0.0353 0.0338
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0197 0.2115
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.042 0.0405
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0026 0.0248 0.0292
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0026 0.0248 0.0233
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0166 0.038
Trichomonas vaginalis set domain proteins, putative 0.0221 0.3457 0.7899
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.042 0.0405
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0413 0.0891
Onchocerca volvulus 0.0026 0.0248 0.0675
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Echinococcus granulosus survival motor neuron protein 1 0.0494 0.7959 0.7956
Echinococcus multilocularis solute carrier family 22 0.0015 0.0056 0.0041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0026 0.0248 0.0233
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Giardia lamblia Sugar-proton symporter 0.0015 0.0056 0.0035
Onchocerca volvulus 0.0015 0.0056 0.0119
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0197 0.0451
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0353 0.0808
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0339 0.0324
Onchocerca volvulus 0.0015 0.0056 0.0119
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0548 0.0533
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Echinococcus multilocularis pyruvate kinase 0.0026 0.024 0.0225
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0057 0.0042
Entamoeba histolytica hypothetical protein 0.0023 0.0197 0.0506
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0057 0.0042
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0021 0.0162 0.037
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0083 0.0068
Entamoeba histolytica protein kinase, putative 0.0032 0.0339 0.0982
Onchocerca volvulus 0.0221 0.3457 1
Loa Loa (eye worm) hypothetical protein 0.013 0.1957 0.246
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Mycobacterium ulcerans glutaminase 0.0277 0.4377 1
Schistosoma mansoni jumonji domain containing protein 0.0055 0.0718 0.0704
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0339 0.0426
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0026 0.0248 0.0292
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0026 0.0248 0.0292
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0057 0.008
Onchocerca volvulus 0.0015 0.0056 0.0119
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0403 0.0936
Echinococcus granulosus solute carrier family 22 0.0015 0.0056 0.0041
Echinococcus multilocularis nAChR subunit 0.0014 0.0049 0.0033
Trichomonas vaginalis inositol monophosphatase, putative 0.0076 0.1063 0.2428
Trypanosoma brucei glucose transporter 1E 0.0032 0.0345 0.0789
Schistosoma mansoni glucose transporter 0.0015 0.0056 0.0041
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0339 0.0324
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.368 0.4624
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.1063 0.2681
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Echinococcus granulosus glycine receptor subunit beta 0.0026 0.0248 0.0233
Brugia malayi DNA topoisomerase III beta-1 0.0014 0.0046 0.0039
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0403 0.0921
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Mycobacterium ulcerans DNA topoisomerase I 0.0014 0.0046 0.0106
Loa Loa (eye worm) hypothetical protein 0.0025 0.0226 0.0283
Plasmodium vivax sugar transporter, putative 0.0015 0.0056 0.008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0078 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0339 0.0324
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1522 0.1509
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0057 0.0042
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0197 0.0182
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0403 0.0388
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0175 0.2696 0.2684
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.1063 0.2681
Brugia malayi beta-lactamase family protein 0.0036 0.0403 0.0488
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0197 0.0451
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0328 0.1001
Onchocerca volvulus 0.0026 0.0248 0.0675
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.014 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0056 0.0129
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0026 0.0248 0.0311
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0035 0.0393 0.0897
Loa Loa (eye worm) hypothetical protein 0.0021 0.0166 0.0209
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0248 0.0292
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0403 0.0936
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0035 0.0393 0.0913
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0345 0.0789
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Onchocerca volvulus 0.0015 0.0056 0.0119
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0035 0.0393 0.0913
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0035 0.0393 0.0913
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0076 0.1063 0.2428
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Echinococcus granulosus pyruvate kinase 0.0017 0.0092 0.0077
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0056 0.0129
Brugia malayi hypothetical protein 0.0015 0.0056 0.0052
Plasmodium vivax acyl-CoA synthetase, putative 0.0016 0.0078 0.011
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0026 0.0248 0.0233
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0353 0.0443
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0403 0.0921
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Echinococcus multilocularis glycine receptor subunit beta 0.0026 0.0248 0.0233
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0306 0.0292
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0014 0.0046 0.0498
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0021 0.0166 0.038
Toxoplasma gondii DNA topoisomerase 2, putative 0.0195 0.3024 0.6523
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0353 0.0808
Echinococcus granulosus General substrate transporter 0.0089 0.1282 0.1269
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0194 0.3016 0.379
Schistosoma mansoni hypothetical protein 0.0037 0.042 0.0405
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0403 0.0921
Brugia malayi jmjC domain containing protein 0.0055 0.0718 0.0884
Schistosoma mansoni inositol monophosphatase 0.0076 0.1063 0.1049
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0248 0.0292
Loa Loa (eye worm) hypothetical protein 0.0015 0.0057 0.0071
Echinococcus granulosus cpg binding protein 0.003 0.0311 0.0296
Plasmodium vivax hexose transporter 0.0104 0.1522 0.2157
Plasmodium falciparum acyl-CoA synthetase 0.0016 0.0078 0.011
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0345 0.0789
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0021 0.0162 0.0285
Schistosoma mansoni survival motor neuron protein 0.0101 0.1477 0.1464
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0067 0.0924 0.9917
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Echinococcus granulosus glycine receptor subunit alpha 1 0.0026 0.0248 0.0233
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0014 0.0049 0.0042
Chlamydia trachomatis DNA gyrase subunit A 0.007 0.0969 0.2482
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1522 0.1509
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0056 0.0071
Onchocerca volvulus 0.0014 0.0046 0.0091
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0166 0.019
Onchocerca volvulus 0.0028 0.0284 0.0782
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0353 0.0808
Loa Loa (eye worm) hypothetical protein 0.0031 0.0328 0.0412
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0076 0.1063 0.2735
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.1063 0.2428
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0028 0.0284 0.0269
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0092 0.013
Schistosoma mansoni protein kinase 0.0032 0.0339 0.0324
Echinococcus granulosus pyruvate kinase 0.0017 0.0092 0.0077
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0026 0.0248 0.0233
Onchocerca volvulus 0.0026 0.0248 0.0675
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0024 0.0209 0.0429
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0014 0.0046 0.0031
Echinococcus granulosus histone lysine methyltransferase setb 0.0028 0.0284 0.0269
Echinococcus multilocularis nAChR subunit 0.0026 0.0248 0.0233
Brugia malayi GRF zinc finger family protein 0.0014 0.0046 0.0039
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0345 0.0789
Schistosoma mansoni cpg binding protein 0.003 0.0311 0.0296
Loa Loa (eye worm) TOPoisomerase family member 0.0195 0.3024 0.38
Loa Loa (eye worm) hypothetical protein 0.013 0.1957 0.246
Onchocerca volvulus 0.0036 0.0403 0.1127
Echinococcus granulosus nAChR subunit 0.0026 0.0248 0.0233
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0056 0.0071
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0197 0.0398
Loa Loa (eye worm) hypothetical protein 0.0021 0.0166 0.0209
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0057 0.0042
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0166 0.0402
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1522 0.1509
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0353 0.0806
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Echinococcus multilocularis lysine specific demethylase 5A 0.0055 0.0718 0.0704
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.072 0.1553
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0403 0.0936
Loa Loa (eye worm) hypothetical protein 0.0026 0.0242 0.0304
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.042 0.0405
Loa Loa (eye worm) hypothetical protein 0.0028 0.0284 0.0357
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0015 0.0071 0.0162
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0395 0.038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.042 0.0528
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Loa Loa (eye worm) hypothetical protein 0.0036 0.0403 0.0507
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Entamoeba histolytica acyl-coA synthetase, putative 0.0021 0.0166 0.0402
Trypanosoma cruzi hexose transporter 0.0032 0.0345 0.0789
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0239 0.3762 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0035 0.0393 0.0913
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0328 0.0394
Toxoplasma gondii protein kinase, putative 0.0293 0.4636 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0015 0.0071 0.0162
Schistosoma mansoni protein kinase 0.0032 0.0339 0.0324
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0166 0.038
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0014 0.0046 0.01
Echinococcus multilocularis rho GTPase activating protein 20 0.0014 0.0046 0.0031
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0413 0.0585
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0284 0.0269
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0345 0.0789
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0339 0.048
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0026 0.0248 0.0292
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0353 0.0806
Plasmodium vivax DNA topoisomerase II, putative 0.0195 0.3024 0.4285
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0175 0.2696 0.3374
Loa Loa (eye worm) hypothetical protein 0.0033 0.0353 0.0443
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.6482 0.6477
Echinococcus granulosus geminin 0.0272 0.4296 0.4287
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0055 0.0718 0.0704
Loa Loa (eye worm) hypothetical protein 0.0021 0.0166 0.0209
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0306 0.0292
Brugia malayi hypothetical protein 0.0035 0.0395 0.0478
Leishmania major hypothetical protein, conserved 0.0015 0.0057 0.0027
Brugia malayi Inositol-1 0.0076 0.1063 0.1319
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0092 0.013
Onchocerca volvulus 0.0036 0.0403 0.1127
Schistosoma mansoni glutaminase 0.0277 0.4377 0.4368
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0175 0.2696 0.2684
Brugia malayi jmjC domain containing protein 0.0015 0.0057 0.0052
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0353 0.0806
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0197 0.0182
Schistosoma mansoni hypothetical protein 0.0104 0.1522 0.1509
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0197 0.0398
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0175 0.2696 0.2684
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0197 0.0279
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0339 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0322 0.0735
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0322 0.0735
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0826 0.0812
Brugia malayi glutaminase DH11.1 0.0277 0.4377 0.549
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0328 0.3521
Schistosoma mansoni inositol monophosphatase 0.0076 0.1063 0.1049
Toxoplasma gondii sugar transporter ST1 0.0015 0.0056 0.0121
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0197 0.0182
Onchocerca volvulus 0.0101 0.1477 0.4248
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Brugia malayi jmjC domain containing protein 0.0015 0.0057 0.0052
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0339 0.0324
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0339 0.048
Schistosoma mansoni hypothetical protein 0.0272 0.4296 0.4287
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0035 0.0393 0.0897
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0056 0.008
Trichomonas vaginalis glutaminase, putative 0.0277 0.4377 1
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0197 0.0425
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0104 0.1522 0.1509
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0393 0.0897
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0548 0.0533
Echinococcus multilocularis cpg binding protein 0.003 0.0311 0.0296
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0014 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Onchocerca volvulus 0.0015 0.0056 0.0119
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0014 0.0046 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0232 0.0292
Plasmodium falciparum mitogen-activated protein kinase 2 0.0167 0.2573 0.3646
Loa Loa (eye worm) sugar transporter 0.0104 0.1522 0.1913
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0024 0.0209 0.0478
Brugia malayi Sugar transporter family protein 0.0104 0.1522 0.1897
Echinococcus multilocularis solute carrier family 22 0.0015 0.0056 0.0041
Onchocerca volvulus 0.0015 0.0056 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0322 0.0735
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0015 0.0071 0.0056
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0345 0.0789
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0116 0.1725 0.2152
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0288 0.0344
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0339 0.048
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.019 0.0484
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0413 0.0967
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Brugia malayi Sugar transporter family protein 0.0015 0.0056 0.0052
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.042 0.051
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0548 0.0533
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Schistosoma mansoni microtubule-associated protein tau 0.0618 1 1
Echinococcus multilocularis glycine receptor subunit beta 0.0026 0.0248 0.0233
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0328 0.0313
Onchocerca volvulus 0.0028 0.0284 0.0781
Mycobacterium leprae Probable lipase LipE 0.0036 0.0403 0.4325
Plasmodium falciparum protein kinase 7 0.0293 0.4636 0.657
Entamoeba histolytica hypothetical protein 0.0035 0.0395 0.117
Leishmania major hypothetical protein, conserved 0.0036 0.0403 0.0941
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0244 0.3838 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0139
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0403 0.0507
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0403 0.0941
Brugia malayi Cam kinase protein 1 0.0032 0.0339 0.0407
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0057 0.0042
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0035 0.0393 0.0378
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Echinococcus granulosus nAChR subunit 0.0014 0.0049 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0345 0.0789
Onchocerca volvulus 0.0014 0.0049 0.0097
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0248 0.0292
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.1063 0.2428
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Echinococcus multilocularis pyruvate kinase 0.0017 0.0092 0.0077
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Loa Loa (eye worm) ACC-1 protein 0.0026 0.0248 0.0311
Leishmania major pyruvate kinase 0.0033 0.0353 0.0808
Onchocerca volvulus 0.0053 0.0698 0.1982
Brugia malayi beta-lactamase family protein 0.0036 0.0403 0.0488
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0339 0.0407
Onchocerca volvulus 0.0036 0.0403 0.1127
Onchocerca volvulus 0.0015 0.0056 0.0119
Schistosoma mansoni jumonji/arid domain-containing protein 0.0056 0.0744 0.073
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0026 0.0248 0.0233
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0014 0.0046 0.0058
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0015 0.0071 0.0162
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0035 0.0393 0.0378
Entamoeba histolytica protein kinase, putative 0.0032 0.0339 0.0982
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0167 0.2573 0.555
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0015 0.0071 0.0089
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0056 0.0026
Toxoplasma gondii sugar transporter ST2 0.0015 0.0056 0.0121
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0197 0.0398
Schistosoma mansoni nAChR subunit 0.0026 0.0248 0.0233
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0403 0.0936
Loa Loa (eye worm) glutaminase 0.0277 0.4377 0.5499
Loa Loa (eye worm) hypothetical protein 0.0016 0.0078 0.0098
Echinococcus multilocularis pyruvate kinase 0.0033 0.0353 0.0338
Brugia malayi Latrophilin receptor protein 2 0.0037 0.042 0.051
Onchocerca volvulus 0.0015 0.0056 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0056 0.0129
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0056 0.0129
Mycobacterium ulcerans hypothetical protein 0.0036 0.0403 0.0921
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0014 0.0049 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.1522 0.3478
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0548 0.0688
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0166 0.019
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0116 0.1725 0.2167
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.014 0.15
Schistosoma mansoni protein kinase 0.0032 0.0339 0.0324
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0403 0.0388
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0057 0.0042
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0035 0.0393 0.0378
Brugia malayi major facilitator superfamily protein 0.0015 0.0056 0.0052
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.042 0.0405
Schistosoma mansoni intermediate filament proteins 0.0053 0.0698 0.0683
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0015 0.0071 0.0056
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0284 0.0613
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0248 0.0292
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0106 0.0156
Plasmodium falciparum DNA topoisomerase 3, putative 0.0014 0.0046 0.0066
Loa Loa (eye worm) acetylcholine receptor protein 0.0012 0.0015 0.0019
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0284 0.0269
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0403 0.0921
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0339 0.0731
Loa Loa (eye worm) hypothetical protein 0.0016 0.0078 0.0098
Echinococcus multilocularis GPCR, family 2 0.0037 0.042 0.0405
Schistosoma mansoni jumonji/arid domain-containing protein 0.0056 0.0744 0.073
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0026 0.0033
Loa Loa (eye worm) hypothetical protein 0.0052 0.0681 0.0856
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0195 0.3024 0.3788
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0056 0.0041
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0328 0.075
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0026 0.0248 0.0311
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0068 0.0932 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) beta-lactamase 0.0036 0.0403 0.0507
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0353 0.0808
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0056 0.0026
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0403 0.4325
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0248 0.0292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0548 0.0533
Loa Loa (eye worm) hypothetical protein 0.0175 0.2696 0.3387
Schistosoma mansoni pyruvate kinase 0.0017 0.0092 0.0077
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.1063 0.2681
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0403 0.0941
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0328 0.0394
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0353 0.05
Onchocerca volvulus 0.0021 0.0166 0.0439
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0403 0.0921
Trypanosoma brucei glucose transporter, putative 0.0032 0.0345 0.0789
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0339 0.048
Echinococcus granulosus glycine receptor subunit alpha 1 0.0026 0.0248 0.0233
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0328 0.0313
Chlamydia trachomatis pyruvate kinase 0.0033 0.0353 0.0824
Loa Loa (eye worm) hypothetical protein 0.0023 0.0197 0.0248
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1522 0.1509
Plasmodium falciparum pyruvate kinase 0.0033 0.0353 0.05
Loa Loa (eye worm) hypothetical protein 0.0494 0.7959 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0061
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Schistosoma mansoni hypothetical protein 0.0037 0.042 0.0405
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0139
Loa Loa (eye worm) hypothetical protein 0.0053 0.0698 0.0876
Echinococcus granulosus dnaJ subfamily B 0.0405 0.6482 0.6477
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Onchocerca volvulus 0.0026 0.0248 0.0675
Onchocerca volvulus Putative transporter 0.0015 0.0056 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0166 0.038
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0026 0.0248 0.0233
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Loa Loa (eye worm) jmjC domain-containing protein 0.0056 0.0744 0.0935
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0056 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0345 0.0789
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0132 0.1991 0.4295
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0057 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0339 0.0774
Onchocerca volvulus 0.0015 0.0056 0.0119
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0248 0.0292
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.014 0.0225
Schistosoma mansoni sugar transporter 0.0015 0.0056 0.0041
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0024 0.0209 0.0478
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0056 0.0026
Onchocerca volvulus 0.0014 0.0049 0.0097
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0078 0.0178
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0339 0.0771
Brugia malayi hypothetical protein 0.0015 0.0056 0.0052
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0057 0.0027
Schistosoma mansoni neurotransmitter gated ion channel 0.0014 0.0049 0.0033
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0173 0.2667 0.7053
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0248 0.0292
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0339 0.0324
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0393 0.0897
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0197 0.0535
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0016 0.0078 0.0058
Loa Loa (eye worm) hypothetical protein 0.0069 0.0947 0.119
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0548 0.0533
Schistosoma mansoni nAChR subunit 0.0026 0.0248 0.0233
Brugia malayi jmjC domain containing protein 0.0015 0.0057 0.0052
Plasmodium vivax DNA gyrase subunit B, putative 0.0173 0.2667 0.3779
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0339 0.048
Brugia malayi hypothetical protein 0.0494 0.7959 1
Plasmodium falciparum DNA topoisomerase 2 0.0195 0.3024 0.4285
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0197 0.0229
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0403 0.0388
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0019
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0016 0.0078 0.0084
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0056 0.0041
Leishmania major glucose transporter, lmgt2 0.0032 0.0345 0.0789
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0015 0.0071 0.0056
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0197 0.0406
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0339 0.0324
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0057 0.0027
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0311
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Onchocerca volvulus 0.0026 0.0248 0.0675
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0393 0.0897
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0173 0.2667 0.7045
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0056 0.0129
Brugia malayi jmjC domain containing protein 0.0015 0.0057 0.0052
Loa Loa (eye worm) inositol-1 0.0076 0.1063 0.1335
Brugia malayi Pre-SET motif family protein 0.0028 0.0284 0.0338
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0026 0.0248 0.0233
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0057 0.0042
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0181 0.2794 0.7247
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0166 0.0297
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.3565 0.9469
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0071
Schistosoma mansoni lamin 0.0053 0.0698 0.0683
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0339 0.048
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.0257 0.0242
Onchocerca volvulus 0.0053 0.0698 0.1982
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0014 0.0046 0.0031
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0166 0.0402
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0064 0.002
Leishmania major glucose transporter, lmgt3 0.0032 0.0345 0.0789
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0239 0.3762 1
Entamoeba histolytica hypothetical protein 0.0035 0.0395 0.117

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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