TDR Targets

Basic information

Technical information

TDR Targets ID: 797477
Name: 3,4,5-triethoxy-N-[2-(4-ethoxyphenyl)benzotri azol-5-yl]benzamide
MW: 490.551 | Formula: C27H30N4O5
H donors: 1 H acceptors: 3 LogP: 5.51 Rotable bonds: 12
Rule of 5 violations (Lipinski): 1
SMILES: CCOc1ccc(cc1)n1nc2c(n1)ccc(c2)NC(=O)c1cc(OCC)c(c(c1)OCC)OCC
InChi: 1S/C27H30N4O5/c1-5-33-21-12-10-20(11-13-21)31-29-22-14-9-19(17-23(22)30-31)28-27(32)18-15-24(34-6-2)26(36-8-4)25(16-18)35-7-3/h9-17H,5-8H2,1-4H3,(H,28,32)
InChiKey: VWNCWOMWWAVMEH-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3,4,5-triethoxy-N-[2-(4-ethoxyphenyl)-5-benzotriazolyl]benzamide
Oprea1_759103
ZINC00847203
3,4,5-Triethoxy-N-[2-(4-ethoxy-phenyl)-2H-benzotriazol-5-yl]-benzamide
BAS 01036029
Oprea1_519688
A2179/0091562

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Toxoplasma gondii	sugar transporter ST2	0.0059	0.0232	0.0346
Plasmodium vivax	threonine--tRNA ligase, putative	0.0024	0.0031	0.0028
Wolbachia endosymbiont of Brugia malayi	major facilitator superfamily permease	0.0059	0.0232	1
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0147	0.073	1
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0147	0.073	1
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Toxoplasma gondii	facilitative glucose transporter GT1	0.042	0.2277	0.3436
Plasmodium falciparum	mitogen-activated protein kinase 2	0.0679	0.3743	0.3742
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0052	0.0192	0.2958
Onchocerca volvulus		0.0059	0.0232	1
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0052	0.0192	0.2958
Trypanosoma cruzi	hexose transporter, putative	0.013	0.0635	0.8703
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0035	0.0093	0.0106
Brugia malayi	glycyl-tRNA synthetase	0.0024	0.0031	0.0136
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0052	0.0192	0.4267
Brugia malayi	MH2 domain containing protein	0.0133	0.0652	0.2865
Echinococcus granulosus	microtubule associated protein 2	0.1513	0.847	1
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.0679	0.3743	0.5651
Loa Loa (eye worm)	MH2 domain-containing protein	0.0133	0.0652	0.2855
Toxoplasma gondii	glycyl-tRNA synthetase	0.0024	0.0031	0.0042
Giardia lamblia	Hexose transporter	0.0059	0.0232	0.346
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0052	0.0192	0.4267
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	CAMK family protein kinase	0.0129	0.0626	0.2739
Trypanosoma cruzi	hypothetical protein, conserved	0.0021	0.0015	0.0171
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.042	0.2277	0.2686
Trichomonas vaginalis	conserved hypothetical protein	0.013	0.0635	0.278
Mycobacterium ulcerans	prolyl-tRNA synthetase	0.0045	0.0149	0.3243
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0502
Trichomonas vaginalis	myo-inositol transporter, putative	0.0059	0.0232	0.1006
Onchocerca volvulus		0.0059	0.0232	1
Brugia malayi	probable proline-trna synthetase - fission yeast, putative	0.0024	0.0031	0.0136
Giardia lamblia	Lysyl-tRNA synthetase	0.0094	0.0428	0.6849
Echinococcus granulosus	survival motor neuron protein 1	0.0264	0.1393	0.1642
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0502
Brugia malayi	Major Facilitator Superfamily protein	0.0059	0.0232	0.1018
Schistosoma mansoni	hypothetical protein	0.0054	0.0202	0.0235
Echinococcus multilocularis	tar DNA binding protein	0.0068	0.0283	0.0331
Toxoplasma gondii	LsmAD domain-containing protein	0.0028	0.0057	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0094	0.0428	0.187
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Leishmania major	glucose transporter/membrane transporter D2, putative	0.013	0.0635	0.8703
Leishmania major	hypothetical protein, conserved	0.0039	0.0117	0.1563
Schistosoma mansoni	hypothetical protein	0.0035	0.0093	0.0106
Toxoplasma gondii	YbaK/proline-tRNA ligase associated domain-containing protein	0.0021	0.0015	0.0019
Chlamydia trachomatis	lysine--tRNA ligase	0.0094	0.0428	1
Plasmodium vivax	hexose transporter	0.042	0.2277	0.2275
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0502
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Mycobacterium leprae	conserved hypothetical protein	0.0039	0.0117	0.1698
Toxoplasma gondii	transporter, major facilitator family protein	0.0059	0.0232	0.0346
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0129	0.0626	0.0736
Schistosoma mansoni	hypothetical protein	0.0035	0.0093	0.0106
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0039	0.0117	0.0788
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Leishmania major	4-coumarate:coa ligase-like protein	0.0052	0.0192	0.2596
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0037	0.0105	0.0699
Mycobacterium tuberculosis	Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase)	0.0024	0.0031	0.0121
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Schistosoma mansoni	glucose transport protein	0.042	0.2277	0.2686
Trypanosoma cruzi	hexose transporter, putative	0.013	0.0635	0.8703
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0611	0.2674
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	hypothetical protein	0.0075	0.032	0.1396
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0039	0.0117	0.0792
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0129	0.0626	0.0942
Leishmania major	hypothetical protein, conserved	0.0059	0.0232	0.3149
Plasmodium falciparum	major facilitator superfamily domain-containing protein, putative	0.0059	0.0232	0.0229
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Schistosoma mansoni	tar DNA-binding protein	0.0068	0.0283	0.0331
Plasmodium falciparum	acyl-CoA synthetase	0.0039	0.0117	0.0114
Brugia malayi	major facilitator superfamily protein	0.0059	0.0232	0.1018
Chlamydia trachomatis	proline--tRNA ligase	0.0045	0.0149	0.2978
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0039	0.0117	0.0134
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0129	0.0626	0.0624
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.0679	0.3743	0.3742
Loa Loa (eye worm)	transcription factor SMAD2	0.0133	0.0652	0.2855
Trypanosoma brucei	glucose transporter 1E	0.013	0.0635	0.868
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.0126	0.0611	0.9763
Onchocerca volvulus		0.0055	0.021	0.9048
Toxoplasma gondii	sugar transporter ST1	0.0059	0.0232	0.0346
Echinococcus granulosus	solute carrier family 22	0.0059	0.0232	0.027
Schistosoma mansoni	glucose transport protein	0.042	0.2277	0.2686
Onchocerca volvulus		0.0059	0.0232	1
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0054	0.0202	0.0888
Trichomonas vaginalis	conserved hypothetical protein	0.042	0.2277	1
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0035	0.0093	0.0106
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0059	0.0232	0.027
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0039	0.0117	0.0788
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0052	0.0192	0.3028
Schistosoma mansoni	tar DNA-binding protein	0.0068	0.0283	0.0331
Trypanosoma brucei	hypothetical protein, conserved	0.0039	0.0117	0.1417
Echinococcus multilocularis	calcium dependent protein kinase	0.0121	0.0581	0.0682
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.0126	0.0611	0.0718
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	TAR-binding protein	0.0068	0.0283	0.1232
Brugia malayi	Cathepsin L-like precursor	0.0019	0.0003	0.0013
Plasmodium vivax	ataxin-2 like protein, putative	0.0028	0.0057	0.0054
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0039	0.0117	0.245
Plasmodium falciparum	lysine--tRNA ligase	0.0094	0.0428	0.0426
Onchocerca volvulus		0.0059	0.0232	1
Loa Loa (eye worm)	sugar transporter	0.0059	0.0232	0.1006
Echinococcus multilocularis	survival motor neuron protein 1	0.0264	0.1393	0.1642
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0192	0.0829
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0129	0.0626	0.0736
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0037	0.0105	0.0699
Leishmania major	4-coumarate:coa ligase-like protein	0.0052	0.0192	0.2596
Loa Loa (eye worm)	hypothetical protein	0.0129	0.0626	0.2739
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0039	0.0117	0.0134
Trichomonas vaginalis	esterase, putative	0.0039	0.0117	0.0499
Mycobacterium ulcerans	acyl-CoA synthetase	0.0052	0.0192	0.4267
Trypanosoma brucei	THT1 - hexose transporter, putative	0.013	0.0635	0.868
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.042	0.2277	0.2686
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0499
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0129	0.0626	0.0624
Leishmania major	protein kinase, putative	0.0129	0.0626	0.8574
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0039	0.0117	0.0788
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0129	0.0626	0.0736
Trypanosoma cruzi	threonyl-tRNA synthetase, putative	0.0024	0.0031	0.0385
Mycobacterium ulcerans	sugar transporter	0.0059	0.0232	0.5239
Trichomonas vaginalis	conserved hypothetical protein	0.013	0.0635	0.278
Echinococcus multilocularis	General substrate transporter	0.0361	0.1943	0.2291
Mycobacterium ulcerans	glycyl-tRNA synthetase	0.0024	0.0031	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0611	0.2674
Entamoeba histolytica	protein kinase, putative	0.0129	0.0626	1
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0129	0.0626	0.0624
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0192	0.0829
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0109	0.0516	0.2267
Leishmania major	myo-inositol/proton symporter (MIT)	0.0059	0.0232	0.3149
Brugia malayi	Major Facilitator Superfamily protein	0.0059	0.0232	0.1018
Loa Loa (eye worm)	hypothetical protein	0.0109	0.0516	0.2257
Schistosoma mansoni	sugar transporter	0.0059	0.0232	0.027
Mycobacterium tuberculosis	Probable lipase LipD	0.0039	0.0117	0.0788
Echinococcus granulosus	glycyl tRNA synthetase	0.0024	0.0031	0.0033
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	hypothetical protein	0.0264	0.1393	0.6112
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0059	0.0232	0.027
Toxoplasma gondii	ABC1 family protein	0.0039	0.0117	0.0172
Trypanosoma brucei	PAB1-binding protein , putative	0.0028	0.0057	0.0576
Brugia malayi	Cathepsin L-like precursor	0.0019	0.0003	0.0013
Onchocerca volvulus		0.0059	0.0232	1
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0126	0.0611	0.0718
Plasmodium vivax	proline--tRNA ligase, putative	0.0147	0.073	0.0727
Giardia lamblia	Sugar-proton symporter	0.0059	0.0232	0.346
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Onchocerca volvulus		0.0052	0.0192	0.8245
Trichomonas vaginalis	sugar transport protein, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Trypanosoma brucei	THT1 - hexose transporter, putative	0.013	0.0635	0.868
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.0126	0.0611	1
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.008	0.0348	0.2592
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0094	0.0428	1
Schistosoma mansoni	protein kinase	0.0129	0.0626	0.0736
Trichomonas vaginalis	glucose transporter, putative	0.0059	0.0232	0.1006
Leishmania major	cathepsin L-like protease	0.0071	0.0301	0.4097
Leishmania major	cathepsin L-like protease	0.0071	0.0301	0.4097
Entamoeba histolytica	glycyl-tRNA synthetase, putative	0.0024	0.0031	0.0449
Entamoeba histolytica	acyl-coA synthetase, putative	0.0052	0.0192	0.3028
Trypanosoma cruzi	glucose transporter, putative	0.0059	0.0232	0.3149
Plasmodium vivax	glycine--tRNA ligase, putative	0.0024	0.0031	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.0126	0.0611	0.0718
Schistosoma mansoni	glucose transporter	0.0059	0.0232	0.027
Trichomonas vaginalis	glucose transporter, putative	0.013	0.0635	0.278
Echinococcus granulosus	tar DNA binding protein	0.0068	0.0283	0.0331
Trichomonas vaginalis	sugar transporter, putative	0.013	0.0635	0.278
Mycobacterium tuberculosis	Probable esterase LipL	0.0039	0.0117	0.0788
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.042	0.2277	0.2686
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0147	0.073	0.1098
Echinococcus granulosus	solute carrier family 22	0.0059	0.0232	0.027
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0232	0.1006
Trypanosoma cruzi	sugar transporter, putative	0.0059	0.0232	0.3149
Echinococcus multilocularis	Threonyl tRNA synthetase, C	0.0024	0.0031	0.0033
Trichomonas vaginalis	D-aminoacylase, putative	0.0039	0.0117	0.0499
Onchocerca volvulus		0.0059	0.0232	1
Trichomonas vaginalis	glucose transporter, putative	0.013	0.0635	0.278
Loa Loa (eye worm)	RNA binding protein	0.0068	0.0283	0.1232
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Echinococcus multilocularis	glycyl tRNA synthetase	0.0024	0.0031	0.0033
Trypanosoma cruzi	hexose transporter, putative	0.013	0.0635	0.8703
Brugia malayi	major facilitator superfamily protein	0.0059	0.0232	0.1018
Echinococcus multilocularis	solute carrier family 22	0.0059	0.0232	0.027
Leishmania major	hypothetical protein, conserved	0.0021	0.0015	0.0171
Schistosoma mansoni	tar DNA-binding protein	0.0068	0.0283	0.0331
Onchocerca volvulus		0.0059	0.0232	1
Brugia malayi	Papain family cysteine protease containing protein	0.0019	0.0003	0.0013
Mycobacterium ulcerans	integral membrane transport protein	0.0059	0.0232	0.5239
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0094	0.0428	0.6932
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0094	0.0428	0.5855
Echinococcus granulosus	calcium dependent protein kinase	0.0121	0.0581	0.0682
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0035	0.0093	0.0106
Onchocerca volvulus		0.0039	0.0117	0.4965
Brugia malayi	AMP-binding enzyme family protein	0.0052	0.0192	0.0841
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0035	0.0093	0.0106
Mycobacterium tuberculosis	Probable lipase LipE	0.0039	0.0117	0.0788
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0129	0.0626	0.0624
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Echinococcus granulosus	GPCR family 2	0.0035	0.0093	0.0106
Echinococcus granulosus	solute carrier family 22	0.0059	0.0232	0.027
Echinococcus multilocularis	lysyl tRNA synthetase	0.0094	0.0428	0.0502
Plasmodium vivax	sugar transporter, putative	0.0059	0.0232	0.0229
Trichomonas vaginalis	penicillin-binding protein, putative	0.0039	0.0117	0.0499
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.0126	0.0611	0.2684
Entamoeba histolytica	hypothetical protein	0.0094	0.0428	0.6828
Brugia malayi	beta-lactamase family protein	0.0039	0.0117	0.0512
Onchocerca volvulus		0.0059	0.0232	1
Trypanosoma brucei	threonyl-tRNA synthetase, putative	0.0024	0.0031	0.0218
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0129	0.0626	0.0736
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0502
Schistosoma mansoni	tar DNA-binding protein	0.0068	0.0283	0.0331
Schistosoma mansoni	protein kinase	0.0129	0.0626	0.0736
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0082	0.0363	0.1582
Mycobacterium leprae	Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.008	0.0348	0.5587
Brugia malayi	Cathepsin L-like precursor	0.0019	0.0003	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Echinococcus multilocularis	GPCR, family 2	0.0035	0.0093	0.0106
Loa Loa (eye worm)	threonyl-tRNA synthetase	0.0024	0.0031	0.0123
Schistosoma mansoni	sugar transporter	0.0059	0.0232	0.027
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0129	0.0626	0.2739
Schistosoma mansoni	sugar transporter	0.0059	0.0232	0.027
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0039	0.0117	0.2168
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0129	0.0626	0.855
Trypanosoma cruzi	Aminoacyl-tRNA editing domain containing protein, putative	0.0021	0.0015	0.0171
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0129	0.0626	0.0736
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.042	0.2277	0.2686
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Trypanosoma cruzi	cysteine peptidase, putative	0.0071	0.0301	0.4097
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Plasmodium falciparum	proline--tRNA ligase	0.0147	0.073	0.0727
Brugia malayi	Sugar transporter family protein	0.0059	0.0232	0.1018
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0052	0.0192	0.1372
Schistosoma mansoni	cellular tumor antigen P53	0.0055	0.021	0.0244
Brugia malayi	latrophilin 2 splice variant baaae	0.0075	0.032	0.1407
Brugia malayi	hypothetical protein	0.0059	0.0232	0.1018
Trichomonas vaginalis	D-aminoacylase, putative	0.0039	0.0117	0.0499
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Plasmodium falciparum	ataxin-2 like protein, putative	0.0028	0.0057	0.0054
Toxoplasma gondii	sugar transporter ST3	0.0059	0.0232	0.0346
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0037	0.0105	0.0699
Entamoeba histolytica	protein kinase, putative	0.0129	0.0626	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0039	0.0117	0.1563
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Brugia malayi	Sugar transporter family protein	0.042	0.2277	1
Brugia malayi	RNA binding protein	0.0068	0.0283	0.1244
Schistosoma mansoni	hypothetical protein	0.042	0.2277	0.2686
Schistosoma mansoni	survival motor neuron protein	0.0054	0.0202	0.0235
Schistosoma mansoni	hypothetical protein	0.0075	0.032	0.0375
Trypanosoma cruzi	cruzipain precursor, putative	0.0071	0.0301	0.4097
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0065	0.0266	0.3615
Brugia malayi	Major Facilitator Superfamily protein	0.0059	0.0232	0.1018
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0129	0.0626	0.0624
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Echinococcus granulosus	General substrate transporter	0.0361	0.1943	0.2291
Toxoplasma gondii	protein kinase, putative	0.1187	0.6622	1
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0059	0.0232	0.5239
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	penicillin-binding protein, putative	0.0039	0.0117	0.0499
Echinococcus granulosus	synaptic vesicle 2 protein	0.0059	0.0232	0.027
Mycobacterium tuberculosis	Conserved protein	0.0039	0.0117	0.0788
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0039	0.0117	0.2464
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.042	0.2277	0.2686
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0232	0.1006
Onchocerca volvulus		0.0039	0.0117	0.4965
Leishmania major	lysyl-tRNA synthetase, putative	0.0094	0.0428	0.5855
Mycobacterium tuberculosis	Probable hydrolase	0.0039	0.0117	0.0788
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0109	0.0516	0.2267
Plasmodium vivax	acyl-CoA synthetase, putative	0.0039	0.0117	0.0114
Brugia malayi	Latrophilin receptor protein 2	0.0035	0.0093	0.0408
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0059	0.0232	0.5239
Trypanosoma cruzi	hexose transporter, putative	0.0071	0.0301	0.4096
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0094	0.0428	1
Brugia malayi	threonyl-tRNA synthetase, cytoplasmic	0.0024	0.0031	0.0136
Leishmania major	glucose transporter, lmgt3	0.013	0.0635	0.8703
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0031	0.0123
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0052	0.0192	0.3028
Brugia malayi	hypothetical protein	0.0059	0.0232	0.1018
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0039	0.0117	0.0134
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0192	0.0829
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0059	0.0232	0.027
Trichomonas vaginalis	conserved hypothetical protein	0.0021	0.0015	0.0055
Schistosoma mansoni	protein kinase	0.0129	0.0626	0.0736
Leishmania major	4-coumarate:coa ligase-like protein	0.0052	0.0192	0.2596
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0052	0.0192	0.4267
Echinococcus multilocularis	microtubule associated protein 2	0.1513	0.847	1
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0094	0.0428	0.187
Brugia malayi	hypothetical protein	0.0028	0.0057	0.0248
Trypanosoma cruzi	Aminoacyl-tRNA editing domain containing protein, putative	0.0021	0.0015	0.0171
Entamoeba histolytica	threonyl-tRNA synthetase, putative	0.0024	0.0031	0.0449
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0147	0.073	1
Trypanosoma brucei	glycyl-tRNA synthetase, putative	0.0024	0.0031	0.0218
Trypanosoma cruzi	hypothetical protein, conserved	0.0021	0.0015	0.0171
Trichomonas vaginalis	threonyl-tRNA synthetase, putative	0.0024	0.0031	0.0123
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0129	0.0626	0.0624
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Brugia malayi	Cathepsin L-like precursor	0.0019	0.0003	0.0013
Onchocerca volvulus		0.0059	0.0232	1
Mycobacterium tuberculosis	Probable conserved integral membrane transport protein	0.0059	0.0232	0.1685
Plasmodium falciparum	ataxin-2 like protein, putative	0.0028	0.0057	0.0054
Loa Loa (eye worm)	bifunctional aminoacyl-tRNA synthetase	0.0052	0.019	0.0823
Mycobacterium ulcerans	hypothetical protein	0.0052	0.0192	0.4267
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.008	0.0348	0.2592
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0499
Onchocerca volvulus		0.0059	0.0232	1
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.042	0.2277	0.2686
Trypanosoma cruzi	hexose transporter	0.013	0.0635	0.8703
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0147	0.073	1
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0129	0.0626	0.0624
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Schistosoma mansoni	microtubule-associated protein tau	0.1513	0.847	1
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0052	0.0192	0.4267
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Leishmania major	glucose transporter, lmgt1	0.013	0.0635	0.8703
Mycobacterium tuberculosis	Conserved protein	0.0039	0.0117	0.0788
Echinococcus multilocularis	solute carrier family 22	0.0059	0.0232	0.027
Plasmodium vivax	lysine--tRNA ligase, putative	0.0094	0.0428	0.0426
Brugia malayi	hypothetical protein	0.0264	0.1393	0.6117
Onchocerca volvulus		0.0059	0.0232	1
Echinococcus multilocularis	solute carrier family 22	0.0059	0.0232	0.027
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0039	0.0117	0.0512
Mycobacterium ulcerans	beta-lactamase	0.0039	0.0117	0.245
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0129	0.0626	0.0736
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Plasmodium vivax	hypothetical protein, conserved	0.0039	0.0117	0.0114
Trypanosoma cruzi	PAB1-binding protein , putative	0.0028	0.0057	0.0737
Schistosoma mansoni	lysyl-tRNA synthetase	0.0094	0.0428	0.0502
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0147	0.073	1
Onchocerca volvulus		0.0059	0.0232	1
Brugia malayi	Cathepsin L-like precursor	0.0019	0.0003	0.0013
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0247	0.1299	1
Trichomonas vaginalis	sugar transporter, putative	0.013	0.0635	0.278
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0052	0.0192	0.1372
Echinococcus granulosus	lysyl tRNA synthetase	0.0094	0.0428	0.0502
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.0126	0.0611	0.2684
Mycobacterium tuberculosis	Conserved protein	0.0039	0.0117	0.0788
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0035	0.0093	0.0396
Trichomonas vaginalis	conserved hypothetical protein	0.0021	0.0015	0.0055
Trypanosoma cruzi	hypothetical protein, conserved	0.0039	0.0117	0.1563
Loa Loa (eye worm)	hypothetical protein	0.0102	0.0477	0.2085
Mycobacterium leprae	Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase)	0.0024	0.0031	0.0262
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0129	0.0626	0.0624
Leishmania major	hypothetical protein, conserved	0.0021	0.0015	0.0171
Schistosoma mansoni	glucose transport protein	0.042	0.2277	0.2686
Brugia malayi	beta-lactamase	0.0039	0.0117	0.0512
Brugia malayi	AMP-binding enzyme family protein	0.0052	0.0192	0.0841
Echinococcus multilocularis	solute carrier family 22	0.0059	0.0232	0.027
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Mycobacterium ulcerans	hypothetical protein	0.0039	0.0117	0.245
Brugia malayi	hypothetical protein	0.0059	0.0232	0.1018
Echinococcus granulosus	Threonyl tRNA synthetase C	0.0024	0.0031	0.0033
Trichomonas vaginalis	conserved hypothetical protein	0.0021	0.0015	0.0055
Brugia malayi	beta-lactamase family protein	0.0039	0.0117	0.0512
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Plasmodium falciparum	hexose transporter	0.042	0.2277	0.2275
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Schistosoma mansoni	hypothetical protein	0.0035	0.0093	0.0106
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	sugar transporter	0.042	0.2277	1
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Onchocerca volvulus	Putative transporter	0.0059	0.0232	1
Schistosoma mansoni	tar DNA-binding protein	0.0068	0.0283	0.0331
Brugia malayi	Cathepsin L-like precursor	0.0019	0.0003	0.0013
Plasmodium vivax	CDK-related protein kinase 6, putative	0.1783	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0059	0.0232	0.1006
Echinococcus multilocularis	tumor protein p63	0.0377	0.2035	0.24
Trichomonas vaginalis	D-aminoacylase, putative	0.0039	0.0117	0.0499
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.042	0.2277	0.2686
Trypanosoma cruzi	major cysteine proteinase, putative	0.0056	0.0214	0.2908
Loa Loa (eye worm)	hypothetical protein	0.0055	0.021	0.091
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0068	0.0283	0.1232
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0129	0.0626	0.0736
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0059	0.0232	0.027
Echinococcus granulosus	solute carrier family 22	0.0059	0.0232	0.027
Trypanosoma cruzi	cysteine peptidase, putative	0.0071	0.0301	0.4097
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0499
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0502
Trypanosoma brucei	glucose transporter 2A	0.013	0.0635	0.868
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Mycobacterium tuberculosis	Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter)	0.0059	0.0232	0.1685
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0129	0.0626	0.0942
Schistosoma mansoni	serine/threonine protein kinase	0.0129	0.0626	0.0736
Mycobacterium ulcerans	acyl-CoA synthetase	0.0052	0.0192	0.4267
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Plasmodium falciparum	protein kinase 7	0.1187	0.6622	0.6621
Toxoplasma gondii	threonyl-tRNA synthetase family protein	0.0024	0.0031	0.0042
Mycobacterium ulcerans	lipase LipD	0.0039	0.0117	0.245
Leishmania major	threonyl-tRNA synthetase, putative	0.0024	0.0031	0.0385
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0094	0.0428	0.5783
Schistosoma mansoni	glycyl-tRNA synthetase	0.0024	0.0031	0.0033
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Mycobacterium ulcerans	esterase/lipase LipP	0.0039	0.0117	0.245
Mycobacterium ulcerans	acyl-CoA synthetase	0.0052	0.0192	0.4267
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0499
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	beta-lactamase	0.0039	0.0117	0.0499
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0057	0.0235
Schistosoma mansoni	sugar transporter	0.0059	0.0232	0.027
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Trypanosoma cruzi	cysteine peptidase, putative	0.0071	0.0301	0.4097
Trypanosoma cruzi	PAB1-binding protein , putative	0.0028	0.0057	0.0737
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0035	0.0093	0.0408
Schistosoma mansoni	lysyl-tRNA synthetase	0.0094	0.0428	0.0502
Schistosoma mansoni	hypothetical protein	0.0035	0.0093	0.0106
Echinococcus granulosus	tumor protein p63	0.0377	0.2035	0.24
Brugia malayi	Sugar transporter family protein	0.0059	0.0232	0.1018
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0129	0.0626	0.0736
Trypanosoma cruzi	threonyl-tRNA synthetase, putative	0.0024	0.0031	0.0385
Brugia malayi	RNA recognition motif domain containing protein	0.0068	0.0283	0.1244
Leishmania major	cathepsin L-like protease	0.0071	0.0301	0.4097
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0039	0.0117	0.0499
Trypanosoma brucei	sugar transporter, putative	0.0059	0.0232	0.303
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0129	0.0626	0.0624
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.042	0.2277	0.2686
Onchocerca volvulus		0.0059	0.0232	1
Brugia malayi	Cam kinase protein 1	0.0129	0.0626	0.2748
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0129	0.0626	0.2748
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0126	0.0611	0.0718
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0499
Brugia malayi	TAR-binding protein	0.0068	0.0283	0.1244
Onchocerca volvulus		0.0059	0.0232	1
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0129	0.0626	0.2739
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Leishmania major	glucose transporter, lmgt2	0.013	0.0635	0.8703
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0093	0.0396
Leishmania major	hypothetical protein, conserved	0.0028	0.0057	0.0737
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0109	0.0516	0.2257
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Loa Loa (eye worm)	glycyl-tRNA synthetase	0.0024	0.0031	0.0123
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0037	0.0105	0.0699
Onchocerca volvulus		0.0059	0.0232	1
Mycobacterium leprae	Probable lipase LipE	0.0039	0.0117	0.1698
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0129	0.0626	0.0942
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.0126	0.0611	0.2674
Giardia lamblia	Prolyl-tRNA synthetase	0.0126	0.0611	1
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0232	0.1006
Trichomonas vaginalis	sugar transporter, putative	0.0059	0.0232	0.1006
Brugia malayi	AMP-binding enzyme family protein	0.0052	0.0192	0.0841
Onchocerca volvulus		0.0054	0.0202	0.8709
Mycobacterium ulcerans	threonyl-tRNA synthetase	0.0024	0.0031	0.0377
Onchocerca volvulus		0.0039	0.0117	0.4965
Treponema pallidum	prolyl-tRNA synthetase	0.0045	0.0149	1
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0117	0.0499
Plasmodium falciparum	threonine--tRNA ligase	0.0024	0.0031	0.0028
Toxoplasma gondii	lysine-tRNA ligase	0.0094	0.0428	0.0643
Trypanosoma brucei	THT1 - hexose transporter, putative	0.013	0.0635	0.868
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0071	0.0301	0.3995
Trypanosoma brucei	glucose transporter, putative	0.013	0.0635	0.868
Trypanosoma brucei	myo-inositol/proton symporter (MIT)	0.0059	0.0232	0.303
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0059	0.0232	0.1006
Trypanosoma cruzi	hexose transporter, putative	0.0059	0.0232	0.3149
Echinococcus granulosus	beta LACTamase domain containing family member	0.0039	0.0117	0.0134
Trichomonas vaginalis	sugar transporter, putative	0.013	0.0635	0.278
Onchocerca volvulus		0.0059	0.0232	1
Brugia malayi	lysyl-tRNA synthetase	0.0094	0.0428	0.1881

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 797477