Detailed information for compound 823702

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 218.295 | Formula: C13H18N2O
  • H donors: 0 H acceptors: 0 LogP: 2.8 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Oc1ccc(cc1)C1N2N1CCC2)C
  • InChi: 1S/C13H18N2O/c1-10(2)16-12-6-4-11(5-7-12)13-14-8-3-9-15(13)14/h4-7,10,13H,3,8-9H2,1-2H3
  • InChiKey: SWUYFHPURRQSRB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus peregrin 0.003 0.0178 0.0518
Trypanosoma brucei rac serine-threonine kinase, putative 0.0026 0.0126 0.1064
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0196 0.0554
Onchocerca volvulus Peroxidasin homolog 0.0084 0.0849 0.2931
Brugia malayi hypothetical protein 0.002 0.0058 0.0236
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0196 0.0554
Schistosoma mansoni biogenic amine receptor 0.0031 0.0196 0.0554
Echinococcus granulosus peroxidasin 0.0084 0.0849 0.2474
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Brugia malayi jmjC domain containing protein 0.0097 0.1021 0.4163
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0058 0.3101
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0256 0.1043
Loa Loa (eye worm) hypothetical protein 0.0136 0.1505 0.6138
Loa Loa (eye worm) hypothetical protein 0.008 0.0804 0.328
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1188 0.3353
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0365 0.103
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0093
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0115 0.6145
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Toxoplasma gondii 6-phosphofructokinase 0.003 0.018 0.9669
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0196 0.0572
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0178 0.0178
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0196 0.08
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0196 0.0572
Brugia malayi Dopamine receptor 0.0031 0.0196 0.08
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0703 0.0703
Schistosoma mansoni myosin xvIII 0.0031 0.0196 0.0554
Brugia malayi G protein-coupled receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1188 0.4847
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0018 0.0033 0.0134
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0196 0.0554
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0196 0.0196
Schistosoma mansoni polycystin 1-related 0.002 0.0058 0.0163
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0196 0.0196
Brugia malayi Serotonin receptor 0.0031 0.0196 0.08
Toxoplasma gondii diacylglycerol kinase, putative 0.0018 0.0033 0.1766
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0166 0.1871 0.1871
Loa Loa (eye worm) hypothetical protein 0.002 0.0058 0.0236
Onchocerca volvulus Chorion peroxidase homolog 0.0084 0.0849 0.2931
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0033 0.0093
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Loa Loa (eye worm) AGC/PKN protein kinase 0.0026 0.0126 0.0516
Loa Loa (eye worm) hypothetical protein 0.0098 0.1021 0.4166
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0196 0.0554
Schistosoma mansoni biogenic amine receptor 0.0031 0.0196 0.0554
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.018 0.5
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0196 0.0572
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0497 0.1449
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0196 0.0572
Brugia malayi hypothetical protein 0.0072 0.0703 0.2868
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus g protein coupled receptor 0.0031 0.0196 0.0572
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0196 0.0572
Echinococcus granulosus N chimaerin 0.0018 0.0033 0.0096
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Brugia malayi GnHR receptor homolog 0.0031 0.0196 0.08
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0196 0.0196
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Brugia malayi RhoGAP domain containing protein 0.0018 0.0033 0.0134
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0187 1
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Schistosoma mansoni rab6-interacting 0.002 0.0058 0.0163
Loa Loa (eye worm) blistered cuticle protein 3 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0196 0.0196
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0196 0.0196
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58
Echinococcus multilocularis peregrin 0.003 0.0178 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Onchocerca volvulus 0.008 0.0804 0.277
Echinococcus granulosus dnaJ subfamily C 6 0.0063 0.0586 0.1707
Echinococcus multilocularis RNA directed DNA polymerase 0.0118 0.1279 0.1279
Loa Loa (eye worm) doublecortin family protein 0.002 0.0058 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Schistosoma mansoni loxhd1 0.002 0.0058 0.0163
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0196 0.0572
Echinococcus granulosus NDR protein kinase 0.0026 0.0126 0.0368
Loa Loa (eye worm) matrixin family protein 0.0178 0.2018 0.8232
Brugia malayi Protein kinase domain containing protein 0.0026 0.0126 0.0516
Echinococcus granulosus fmrfamide receptor 0.0031 0.0196 0.0572
Schistosoma mansoni protein kinase C mu 0.0019 0.004 0.0112
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus Diacylglycerol kinase theta 0.0018 0.0033 0.0096
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni rac gtpase activating protein 0.0018 0.0033 0.0093
Brugia malayi RhoGAP domain containing protein 0.0018 0.0033 0.0134
Onchocerca volvulus 0.0031 0.0196 0.0586
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.018 0.9669
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1188 1
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0058 0.0058
Brugia malayi diacylglycerol kinase 0.0018 0.0033 0.0134
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus granulosus protein kinase C gamma type 0.0148 0.1645 0.4794
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0019 0.004 0.0163
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0187 0.0527
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0098 0.1021 0.4166
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Brugia malayi 6-phosphofructokinase 0.0111 0.1188 0.4847
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Echinococcus granulosus serine:threonine protein kinase N2 0.0026 0.0126 0.0368
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Echinococcus multilocularis neuropeptide receptor A26 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis serotonin receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0019 0.004 0.0163
Schistosoma mansoni hypothetical protein 0.0166 0.1874 0.5285
Schistosoma mansoni lipoxygenase 0.0056 0.0509 0.1435
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0026 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus RUN 0.002 0.0058 0.0169
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0497 0.2028
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Echinococcus granulosus protein kinase c iota type 0.0044 0.0352 0.1026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.018 0.9669
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0187 0.0187
Schistosoma mansoni opsin-like receptor 0.0031 0.0196 0.0554
Schistosoma mansoni hypothetical protein 0.002 0.0058 0.0163
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0196 0.0572
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0173 0.0503
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0256 0.0256
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0033 0.0134
Brugia malayi Serotonin receptor 0.0031 0.0196 0.08
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.018 1
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.1263 0.5152
Brugia malayi Protein kinase c protein 2 0.0141 0.1559 0.6357
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0022 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0196 0.0586
Onchocerca volvulus Peroxidasin homolog 0.0084 0.0849 0.2931
Brugia malayi hypothetical protein 0.0025 0.0115 0.0468
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0026 0.0126 0.0368
Loa Loa (eye worm) MBCTL1 0.0055 0.0497 0.2028
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0413 0.0413
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0536 0.1563
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0196 0.0572
Schistosoma mansoni hypothetical protein 0.0106 0.1123 0.3167
Schistosoma mansoni peroxidasin 0.0084 0.0849 0.2395
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0196 0.08
Brugia malayi G-protein coupled receptor 0.0031 0.0196 0.08
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0413 0.1166
Schistosoma mansoni hypothetical protein 0.0166 0.1874 0.5285
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1871 0.5277
Echinococcus multilocularis Diacylglycerol kinase theta 0.0018 0.0033 0.0033
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0019 0.004 0.0116
Echinococcus multilocularis sex peptide receptor 0.0031 0.0196 0.0196
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0497 0.0497
Brugia malayi 6-phosphofructokinase 0.0111 0.1188 0.4847
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0192 0.2196 0.6398
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0026 0.0126 0.0516
Echinococcus granulosus g protein coupled receptor 0.0031 0.0196 0.0572
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0509 0.0509
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Echinococcus granulosus sex peptide receptor 0.0031 0.0196 0.0572
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0018 0.0033 0.0096
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0365 0.103
Onchocerca volvulus 0.0031 0.0196 0.0586
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0365 0.1489
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0019 0.004 0.0163
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus geminin 0.0166 0.1874 0.546
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0196 0.0196
Echinococcus multilocularis serine:threonine protein kinase 38 0.0026 0.0126 0.0126
Brugia malayi Matrixin family protein 0.0194 0.2218 0.9045
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0509 0.1483
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0703 0.2049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0196 0.0554
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0497 0.1403
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1188 0.4847
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0187 0.0187
Brugia malayi sulfakinin receptor protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0022 0.008 0.0326
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Brugia malayi phosphofructokinase 0.0111 0.1188 0.4847
Brugia malayi Ras association domain family 1 isoform A 0.0018 0.0033 0.0134
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0196 0.08
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0572
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0413 0.1166
Brugia malayi larval opioid receptor 0.0031 0.0196 0.08
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0536 0.4512
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni histamine h1 receptor 0.0031 0.0196 0.0554
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0022 0.008 0.0233
Brugia malayi Dopamine receptor protein 2 0.0031 0.0196 0.08
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1188 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0187 0.0527
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Schistosoma mansoni hypothetical protein 0.0072 0.0703 0.1984
Echinococcus granulosus RNA directed DNA polymerase 0.0118 0.1279 0.3728
Brugia malayi mbt repeat family protein 0.0049 0.0413 0.1686
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0058 0.0169
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0365 0.1489
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0196 0.0554
Brugia malayi Melatonin receptor type 1A 0.0031 0.0196 0.08
Echinococcus granulosus somatostatin receptor 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0196 0.0196
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0058 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0365 0.103
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0196 0.08
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0196 0.0196
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Echinococcus granulosus orexin receptor type 2 0.0031 0.0196 0.0572
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0126 0.0126
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Echinococcus multilocularis conserved hypothetical protein 0.0298 0.3521 0.3521
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0018 0.0033 0.0033
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0026 0.0126 0.0368
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0026 0.0126 0.0516
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0399 0.1125
Loa Loa (eye worm) matrixin family protein 0.0194 0.2218 0.9045
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Toxoplasma gondii AGC kinase 0.0026 0.0126 0.6774
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0196 0.0196
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Brugia malayi neuropeptide F receptor 0.0031 0.0196 0.08
Brugia malayi hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0085 0.086 0.2425
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0178 0.9525
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0572
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0196 0.08
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Echinococcus granulosus neuropeptide receptor 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0365 0.1064
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0196 0.0196
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Schistosoma mansoni diacylglycerol kinase theta 0.0018 0.0033 0.0093
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.1188 0.1188
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.008 0.0804 0.2268
Echinococcus granulosus g protein coupled receptor 0.0031 0.0196 0.0572
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Schistosoma mansoni glucose-6-phosphatase 0.03 0.3545 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Loa Loa (eye worm) matrix metalloproteinase 0.008 0.0804 0.328
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Echinococcus multilocularis peroxidasin 0.0084 0.0849 0.0849
Onchocerca volvulus 0.0084 0.0849 0.2931
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni atypical protein kinase C 0.0044 0.0352 0.0993
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0026 0.0126 0.0126
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0033 0.0134
Echinococcus multilocularis G protein coupled receptor 139 0.0031 0.0196 0.0196
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0115 0.6355
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0196 0.0554
Onchocerca volvulus Matrilysin homolog 0.008 0.0804 0.277
Schistosoma mansoni biogenic amine receptor 0.0031 0.0196 0.0554
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0115 0.6145
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0771 0.2176
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0196 0.0554
Echinococcus granulosus Protein kinase C brain isozyme 0.0166 0.1871 0.5451
Echinococcus granulosus serotonin receptor 0.0031 0.0196 0.0572
Echinococcus granulosus unc 13 munc13 0.0022 0.008 0.0233
Brugia malayi PHD-finger family protein 0.003 0.0178 0.0725
Brugia malayi Doublecortin family protein 0.002 0.0058 0.0236
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.1188 1
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0118 0.1279 0.1279
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.1021 0.2974
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0413 0.1205
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0058 0.0169
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni opsin-like receptor 0.0031 0.0196 0.0554
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0192 0.2196 0.2196
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0196 0.0572
Brugia malayi Protein kinase domain containing protein 0.0026 0.0126 0.0516
Onchocerca volvulus 0.0114 0.1221 0.4266
Onchocerca volvulus Peroxidase homolog 0.0084 0.0849 0.2931
Brugia malayi p70 ribosomal S6 kinase beta 0.0026 0.0126 0.0516
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Schistosoma mansoni adenoreceptor 0.0031 0.0196 0.0554
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0196 0.0572
Onchocerca volvulus 0.0084 0.0849 0.2931
Schistosoma mansoni protein kinase C mu 0.0018 0.0033 0.0093
Onchocerca volvulus 0.0022 0.008 0.0168
Brugia malayi ORL1-like opioid receptor 0.0031 0.0196 0.08
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.003 0.0178 0.0725
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0196 0.08
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0058 0.0169
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.1188 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0196 0.0196
Echinococcus multilocularis dnaJ subfamily C 6 0.0063 0.0586 0.0586
Onchocerca volvulus Dual oxidase homolog 0.0084 0.0849 0.2931
Brugia malayi DnaJ domain containing protein 0.0063 0.0586 0.2389
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0497 0.0497
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis Rac GTPase activating protein 1 0.0018 0.0033 0.0033
Brugia malayi hypothetical protein 0.0016 0.0006 0.0024
Loa Loa (eye worm) AGC/NDR protein kinase 0.0026 0.0126 0.0516
Brugia malayi Pre-SET motif family protein 0.003 0.0187 0.0761
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0187 0.0527
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Brugia malayi Protein kinase domain containing protein 0.0019 0.004 0.0163
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0536 0.0536
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0196 0.08
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0115 0.0965
Loa Loa (eye worm) DnaJ domain-containing protein 0.0063 0.0586 0.2389
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Trichomonas vaginalis set domain proteins, putative 0.0242 0.2817 1
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0196 0.08
Brugia malayi Pre-SET motif family protein 0.0212 0.2452 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0497 0.2028
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.1021 0.1021
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58
Loa Loa (eye worm) RasGEF domain-containing protein 0.0018 0.0033 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0178 0.9525
Loa Loa (eye worm) hypothetical protein 0.008 0.0804 0.328
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0196 0.0196
Echinococcus multilocularis geminin 0.0166 0.1874 0.1874
Echinococcus granulosus protein kinase c eta type 0.0018 0.0033 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Brugia malayi Pleckstrin Homology Domain 0.0018 0.0033 0.0134
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0196 0.0586
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1871 0.5277
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.002 0.0058 0.0236
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Mycobacterium ulcerans hydrolase 0.0098 0.1021 0.7439
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0196 0.0196
Brugia malayi protein kinase C3,putative 0.0019 0.004 0.0163
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0187 0.0527
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.1188 0.3463
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Schistosoma mansoni hypothetical protein 0.0063 0.0586 0.1652
Schistosoma mansoni unc-13 (munc13) 0.0022 0.008 0.0225
Schistosoma mansoni lipoxygenase 0.002 0.0058 0.0163
Echinococcus multilocularis protein kinase c iota type 0.0044 0.0352 0.0352
Echinococcus multilocularis raf serine:threonine protein kinase 0.0018 0.0033 0.0033
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0178 0.0725
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1188 1
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0098 0.1021 0.8594
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0196 0.0572
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0196 0.0196
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.018 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.004 0.0112
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0196 0.0196
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1188 1
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0196 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.004 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0033 0.0093
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0291 0.3432 0.3432
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0018 0.0033 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0115 0.0965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0196 0.0572
Echinococcus multilocularis unc 13 (munc13) 0.0022 0.008 0.008
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.1188 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0187 0.0761
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0196 0.0554
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0196 0.0196
Schistosoma mansoni opsin-like receptor 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0031 0.0196 0.0586
Plasmodium falciparum phd finger protein, putative 0.003 0.0178 0.9851
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0196 0.0554
Onchocerca volvulus Alhambra homolog 0.003 0.0178 0.052
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus granulosus protein kinase c epsilon type 0.0048 0.0399 0.1162
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1188 0.3353
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0196 0.0572
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Schistosoma mansoni diacylglycerol kinase theta 0.0018 0.0033 0.0093
Trichomonas vaginalis protein kinase inhibitor, putative 0.0063 0.0586 0.1728
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Onchocerca volvulus 0.0031 0.0196 0.0586
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.018 1
Onchocerca volvulus Matrilysin homolog 0.0178 0.2018 0.7131
Schistosoma mansoni hypothetical protein 0.0296 0.3492 0.985
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Onchocerca volvulus 0.0084 0.0849 0.2931
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0123 0.1333 0.5437
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.018 0.5
Trypanosoma brucei RNA helicase, putative 0.0106 0.1123 0.9446
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0256 0.0721
Brugia malayi G-protein coupled receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0025 0.0115 0.0468
Loa Loa (eye worm) hypothetical protein 0.008 0.0804 0.328
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0196
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0196 0.0572
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0026 0.0126 0.0368
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0703 0.1984
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) AGC/AKT protein kinase 0.0026 0.0126 0.0516
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0196 0.0196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0196 0.0196
Onchocerca volvulus 0.0031 0.0196 0.0586
Loa Loa (eye worm) hypothetical protein 0.0118 0.1279 0.5217
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0291 0.3432 1
Onchocerca volvulus 0.003 0.0187 0.0552
Brugia malayi Peroxidasin 0.0084 0.0849 0.3463
Echinococcus multilocularis protein kinase c epsilon type 0.0048 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0196 0.0196
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0196 0.0572
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0187 0.0544
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0196 0.0196
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Brugia malayi Bromodomain containing protein 0.003 0.0178 0.0725
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Brugia malayi RE15519p 0.0031 0.0196 0.08
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus granulosus neuropeptide s receptor 0.0031 0.0196 0.0572
Echinococcus granulosus raf serine:threonine protein kinase 0.0018 0.0033 0.0096
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0196 0.0572
Plasmodium vivax SET domain protein, putative 0.003 0.0187 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0365 0.0365
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0196 0.08
Echinococcus multilocularis myotubularin protein 13 0.0018 0.0033 0.0033
Brugia malayi diacylglycerol kinase 0.0018 0.0033 0.0134
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0196 0.08
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Brugia malayi putative neuropeptide receptor 0.0031 0.0196 0.08
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0196 0.0572
Brugia malayi AKH receptor 0.0031 0.0196 0.08
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0026 0.0126 0.0516
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Brugia malayi jmjC domain containing protein 0.0036 0.0256 0.1043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0365 0.0365
Echinococcus multilocularis conserved hypothetical protein 0.0298 0.3521 0.3521
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0365 0.1064
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0196 0.08
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0256 0.0721
Brugia malayi neuropeptide F receptor 0.0031 0.0196 0.08
Brugia malayi protein kinase C II. 0.0048 0.0399 0.1627
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0048 0.0399 0.1627
Brugia malayi Dopamine receptor protein 1 0.0031 0.0196 0.08
Onchocerca volvulus 0.0242 0.2817 1
Echinococcus multilocularis N chimaerin 0.0018 0.0033 0.0033
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0497 0.1449
Echinococcus multilocularis somatostatin receptor 0.0031 0.0196 0.0196
Brugia malayi follicle stimulating hormone receptor 0.0031 0.0196 0.08
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0058 0.0058
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0196 0.0572
Schistosoma mansoni hypothetical protein 0.003 0.0178 0.0502
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus multilocularis protein kinase c eta type 0.0018 0.0033 0.0033
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0026 0.0126 0.0516
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0487 0.1987
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0323 0.0941
Brugia malayi hypothetical protein 0.002 0.0058 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Onchocerca volvulus Peroxidase homolog 0.0084 0.0849 0.2931
Brugia malayi Hemopexin family protein 0.0114 0.1221 0.4979
Schistosoma mansoni serine/threonine kinase 0.0026 0.0126 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Onchocerca volvulus Matrix metalloproteinase homolog 0.0178 0.2018 0.7131
Brugia malayi mbt repeat family protein 0.0049 0.0413 0.1686
Echinococcus multilocularis RUN 0.002 0.0058 0.0058
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0413 0.0413
Loa Loa (eye worm) phosphofructokinase 0.0111 0.1188 0.4847
Onchocerca volvulus 0.002 0.0058 0.0089
Echinococcus granulosus neuropeptide receptor 0.0031 0.0196 0.0572
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0413 0.1205
Schistosoma mansoni unc-13 (munc13) 0.0024 0.0103 0.0291
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0256 0.0745
Echinococcus multilocularis neuropeptide s receptor 0.0031 0.0196 0.0196
Brugia malayi MH2 domain containing protein 0.0117 0.1263 0.5152
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0196 0.0554
Brugia malayi Hr1 repeat family protein 0.0026 0.0126 0.0516
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0115 0.0965
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.018 0.1277
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Schistosoma mansoni protein kinase C 0.0022 0.008 0.0225
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.1188 1
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0058 0.3207
Brugia malayi C1-like domain containing protein 0.0019 0.004 0.0163
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0196 0.0572
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0572 0.2334
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.018 0.9669
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0178 0.0518
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0196 0.0554
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1188 1
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Loa Loa (eye worm) raf kinase 0.0018 0.0033 0.0134
Echinococcus granulosus myotubularin protein 13 0.0018 0.0033 0.0096
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.2452 1
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0033 0.0093
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0196 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Onchocerca volvulus 0.0031 0.0196 0.0586
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0413 0.1166
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0026 0.0126 0.0516
Echinococcus granulosus allatostatin A receptor 0.0031 0.0196 0.0572
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Schistosoma mansoni hypothetical protein 0.0114 0.1221 0.3444
Loa Loa (eye worm) hypothetical protein 0.0049 0.0413 0.1686
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0196 0.0572
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.1263 0.5152
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0413 0.1367
Plasmodium vivax hypothetical protein, conserved 0.003 0.0178 0.9525
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0196 0.0554
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0196 0.0196
Brugia malayi RhoGEF domain containing protein 0.0018 0.0033 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0442 0.1805
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0196 0.08
Echinococcus granulosus hypothetical protein 0.0031 0.0196 0.0572
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0196 0.08
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0019 0.004 0.004
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0178 0.0502
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0196 0.08
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis serine threonine protein kinase 0.0148 0.1645 0.1645
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0196 0.0554
Echinococcus granulosus Rac GTPase activating protein 1 0.0018 0.0033 0.0096
Echinococcus granulosus neuropeptide receptor A26 0.0031 0.0196 0.0572
Onchocerca volvulus 0.0031 0.0196 0.0586
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0536 0.4512
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0536 0.1513
Echinococcus multilocularis serotonin receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Schistosoma mansoni rab6-interacting 0.002 0.0058 0.0163
Onchocerca volvulus 0.0049 0.0413 0.1367
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.1188 1
Brugia malayi Blistered cuticle protein 3 0.0084 0.0849 0.3463
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0196 0.0196
Schistosoma mansoni vav2 0.0018 0.0033 0.0093
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.018 0.9669
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0196 0.0554
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0196 0.08
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0196 0.0196
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.018 1
Onchocerca volvulus 0.002 0.0058 0.0089
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0115 0.6355
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Leishmania major hypothetical protein, conserved 0.0025 0.0115 0.0965
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0026 0.0126 0.0126
Schistosoma mansoni peroxidasin 0.0084 0.0849 0.2395
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0031 0.0196 0.0586
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0536 0.2187
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0196 0.08
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0196 0.0572
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0413 0.1686
Onchocerca volvulus 0.0031 0.0196 0.0586
Brugia malayi Protein kinase domain containing protein 0.0026 0.0126 0.0516

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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