Detailed information for compound 823741

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 204.268 | Formula: C12H16N2O
  • H donors: 0 H acceptors: 0 LogP: 2.36 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)C1N2N1CCC2
  • InChi: 1S/C12H16N2O/c1-2-15-11-6-4-10(5-7-11)12-13-8-3-9-14(12)13/h4-7,12H,2-3,8-9H2,1H3
  • InChiKey: AYQMBALOZJJPKE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0365 0.0365
Brugia malayi jmjC domain containing protein 0.0036 0.0256 0.1043
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0026 0.0126 0.0516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Brugia malayi AKH receptor 0.0031 0.0196 0.08
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0196 0.0572
Brugia malayi putative neuropeptide receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Brugia malayi protein kinase C II. 0.0048 0.0399 0.1627
Brugia malayi neuropeptide F receptor 0.0031 0.0196 0.08
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0256 0.0721
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0196 0.08
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0365 0.1064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis conserved hypothetical protein 0.0298 0.3521 0.3521
Schistosoma mansoni hypothetical protein 0.003 0.0178 0.0502
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0196 0.0572
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Brugia malayi follicle stimulating hormone receptor 0.0031 0.0196 0.08
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0058 0.0058
Echinococcus multilocularis somatostatin receptor 0.0031 0.0196 0.0196
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0497 0.1449
Echinococcus multilocularis N chimaerin 0.0018 0.0033 0.0033
Onchocerca volvulus 0.0242 0.2817 1
Brugia malayi Dopamine receptor protein 1 0.0031 0.0196 0.08
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0048 0.0399 0.1627
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Brugia malayi hypothetical protein 0.002 0.0058 0.0236
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0323 0.0941
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0487 0.1987
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0026 0.0126 0.0516
Echinococcus multilocularis protein kinase c eta type 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Schistosoma mansoni serine/threonine kinase 0.0026 0.0126 0.0357
Brugia malayi Hemopexin family protein 0.0114 0.1221 0.4979
Onchocerca volvulus Peroxidase homolog 0.0084 0.0849 0.2931
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0196 0.0196
Schistosoma mansoni unc-13 (munc13) 0.0024 0.0103 0.0291
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0413 0.1205
Echinococcus granulosus neuropeptide receptor 0.0031 0.0196 0.0572
Onchocerca volvulus 0.002 0.0058 0.0089
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0413 0.0413
Echinococcus multilocularis RUN 0.002 0.0058 0.0058
Loa Loa (eye worm) phosphofructokinase 0.0111 0.1188 0.4847
Brugia malayi mbt repeat family protein 0.0049 0.0413 0.1686
Onchocerca volvulus Matrix metalloproteinase homolog 0.0178 0.2018 0.7131
Schistosoma mansoni protein kinase C 0.0022 0.008 0.0225
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.018 0.1277
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0115 0.0965
Brugia malayi Hr1 repeat family protein 0.0026 0.0126 0.0516
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0196 0.0554
Brugia malayi MH2 domain containing protein 0.0117 0.1263 0.5152
Echinococcus multilocularis neuropeptide s receptor 0.0031 0.0196 0.0196
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0256 0.0745
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0572 0.2334
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0196 0.0572
Brugia malayi C1-like domain containing protein 0.0019 0.004 0.0163
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0058 0.3207
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.1188 1
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0033 0.0093
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.2452 1
Loa Loa (eye worm) raf kinase 0.0018 0.0033 0.0134
Echinococcus granulosus myotubularin protein 13 0.0018 0.0033 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1188 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0178 0.0518
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.018 0.9669
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0413 0.1367
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.1263 0.5152
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0196 0.0572
Schistosoma mansoni hypothetical protein 0.0114 0.1221 0.3444
Loa Loa (eye worm) hypothetical protein 0.0049 0.0413 0.1686
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Echinococcus granulosus allatostatin A receptor 0.0031 0.0196 0.0572
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0026 0.0126 0.0516
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0413 0.1166
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Onchocerca volvulus 0.0031 0.0196 0.0586
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0196 0.08
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0196 0.0196
Echinococcus granulosus hypothetical protein 0.0031 0.0196 0.0572
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0051 0.0442 0.1805
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0196 0.0196
Brugia malayi RhoGEF domain containing protein 0.0018 0.0033 0.0134
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0196 0.0554
Plasmodium vivax hypothetical protein, conserved 0.003 0.0178 0.9525
Echinococcus granulosus neuropeptide receptor A26 0.0031 0.0196 0.0572
Echinococcus granulosus Rac GTPase activating protein 1 0.0018 0.0033 0.0096
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0196 0.0554
Echinococcus multilocularis serine threonine protein kinase 0.0148 0.1645 0.1645
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0196 0.0196
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0178 0.0502
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0196 0.08
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0019 0.004 0.004
Schistosoma mansoni rab6-interacting 0.002 0.0058 0.0163
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus multilocularis serotonin receptor 0.0031 0.0196 0.0196
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0536 0.1513
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0536 0.4512
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni vav2 0.0018 0.0033 0.0093
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.018 0.9669
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0196 0.0196
Brugia malayi Blistered cuticle protein 3 0.0084 0.0849 0.3463
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.1188 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0049 0.0413 0.1367
Leishmania major hypothetical protein, conserved 0.0025 0.0115 0.0965
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0196 0.0572
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0115 0.6355
Onchocerca volvulus 0.002 0.0058 0.0089
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.018 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0196 0.0196
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0196 0.08
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0196 0.0554
Brugia malayi Protein kinase domain containing protein 0.0026 0.0126 0.0516
Onchocerca volvulus 0.0031 0.0196 0.0586
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0413 0.1686
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0196 0.0572
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0196 0.08
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0536 0.2187
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Schistosoma mansoni peroxidasin 0.0084 0.0849 0.2395
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0026 0.0126 0.0126
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0196
Brugia malayi ORL1-like opioid receptor 0.0031 0.0196 0.08
Onchocerca volvulus 0.0022 0.008 0.0168
Schistosoma mansoni protein kinase C mu 0.0018 0.0033 0.0093
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0196 0.0572
Onchocerca volvulus 0.0084 0.0849 0.2931
Schistosoma mansoni adenoreceptor 0.0031 0.0196 0.0554
Onchocerca volvulus Dual oxidase homolog 0.0084 0.0849 0.2931
Echinococcus multilocularis dnaJ subfamily C 6 0.0063 0.0586 0.0586
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.1188 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0196 0.08
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0058 0.0169
Loa Loa (eye worm) hypothetical protein 0.003 0.0178 0.0725
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0187 0.0527
Brugia malayi Pre-SET motif family protein 0.003 0.0187 0.0761
Loa Loa (eye worm) AGC/NDR protein kinase 0.0026 0.0126 0.0516
Brugia malayi hypothetical protein 0.0016 0.0006 0.0024
Echinococcus multilocularis Rac GTPase activating protein 1 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0196 0.0554
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0497 0.0497
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Brugia malayi DnaJ domain containing protein 0.0063 0.0586 0.2389
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.1021 0.1021
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi Pre-SET motif family protein 0.0212 0.2452 1
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0055 0.0497 0.2028
Trichomonas vaginalis set domain proteins, putative 0.0242 0.2817 1
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Loa Loa (eye worm) DnaJ domain-containing protein 0.0063 0.0586 0.2389
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0115 0.0965
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0536 0.0536
Brugia malayi Protein kinase domain containing protein 0.0019 0.004 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Loa Loa (eye worm) hypothetical protein 0.008 0.0804 0.328
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0178 0.9525
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Loa Loa (eye worm) RasGEF domain-containing protein 0.0018 0.0033 0.0134
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0196 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1871 0.5277
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0196 0.0554
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0196 0.0586
Echinococcus granulosus protein kinase c eta type 0.0018 0.0033 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Brugia malayi Pleckstrin Homology Domain 0.0018 0.0033 0.0134
Echinococcus multilocularis geminin 0.0166 0.1874 0.1874
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0196 0.0196
Echinococcus multilocularis protein kinase c iota type 0.0044 0.0352 0.0352
Echinococcus multilocularis raf serine:threonine protein kinase 0.0018 0.0033 0.0033
Schistosoma mansoni lipoxygenase 0.002 0.0058 0.0163
Schistosoma mansoni unc-13 (munc13) 0.0022 0.008 0.0225
Schistosoma mansoni hypothetical protein 0.0063 0.0586 0.1652
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0187 0.0527
Brugia malayi protein kinase C3,putative 0.0019 0.004 0.0163
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.1188 0.3463
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Mycobacterium ulcerans hydrolase 0.0098 0.1021 0.7439
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.002 0.0058 0.0236
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0196 0.0196
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1188 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0196 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.004 0.0112
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.018 0.0226
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0196 0.0196
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0196 0.0572
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0098 0.1021 0.8594
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1188 1
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0178 0.0725
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0196 0.0572
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0115 0.0965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0018 0.0033 0.0134
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0291 0.3432 0.3432
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0033 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.004 0.0112
Echinococcus granulosus protein kinase c epsilon type 0.0048 0.0399 0.1162
Onchocerca volvulus Alhambra homolog 0.003 0.0178 0.052
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0196 0.0554
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Plasmodium falciparum phd finger protein, putative 0.003 0.0178 0.9851
Schistosoma mansoni opsin-like receptor 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0196 0.0196
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0196 0.0554
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.1188 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0187 0.0761
Echinococcus multilocularis unc 13 (munc13) 0.0022 0.008 0.008
Onchocerca volvulus Matrilysin homolog 0.0178 0.2018 0.7131
Schistosoma mansoni hypothetical protein 0.0296 0.3492 0.985
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.018 1
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Onchocerca volvulus 0.0031 0.0196 0.0586
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis protein kinase inhibitor, putative 0.0063 0.0586 0.1728
Schistosoma mansoni diacylglycerol kinase theta 0.0018 0.0033 0.0093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0196 0.0572
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1188 0.3353
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0196 0.0572
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.008 0.0804 0.328
Trypanosoma brucei RNA helicase, putative 0.0106 0.1123 0.9446
Brugia malayi G-protein coupled receptor 0.0031 0.0196 0.08
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0256 0.0721
Loa Loa (eye worm) hypothetical protein 0.0025 0.0115 0.0468
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.018 0.5
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0123 0.1333 0.5437
Onchocerca volvulus 0.0084 0.0849 0.2931
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Loa Loa (eye worm) hypothetical protein 0.0118 0.1279 0.5217
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0196 0.0196
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) AGC/AKT protein kinase 0.0026 0.0126 0.0516
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0196 0.0554
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0703 0.1984
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0026 0.0126 0.0368
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi Peroxidasin 0.0084 0.0849 0.3463
Echinococcus multilocularis protein kinase c epsilon type 0.0048 0.0399 0.0399
Onchocerca volvulus 0.003 0.0187 0.0552
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0291 0.3432 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Brugia malayi RE15519p 0.0031 0.0196 0.08
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Brugia malayi Bromodomain containing protein 0.003 0.0178 0.0725
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0196 0.0196
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0187 0.0544
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0196 0.0572
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0196 0.08
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Brugia malayi diacylglycerol kinase 0.0018 0.0033 0.0134
Echinococcus multilocularis myotubularin protein 13 0.0018 0.0033 0.0033
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0196 0.08
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0365 0.0365
Plasmodium vivax SET domain protein, putative 0.003 0.0187 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0196 0.0572
Echinococcus granulosus raf serine:threonine protein kinase 0.0018 0.0033 0.0096
Echinococcus granulosus neuropeptide s receptor 0.0031 0.0196 0.0572
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1871 0.5277
Schistosoma mansoni hypothetical protein 0.0166 0.1874 0.5285
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0413 0.1166
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Brugia malayi G-protein coupled receptor 0.0031 0.0196 0.08
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0196 0.08
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0026 0.0126 0.0516
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0192 0.2196 0.6398
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Brugia malayi 6-phosphofructokinase 0.0111 0.1188 0.4847
Echinococcus multilocularis sex peptide receptor 0.0031 0.0196 0.0196
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0497 0.0497
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0019 0.004 0.0116
Echinococcus multilocularis Diacylglycerol kinase theta 0.0018 0.0033 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0365 0.1489
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0365 0.103
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0018 0.0033 0.0096
Echinococcus granulosus sex peptide receptor 0.0031 0.0196 0.0572
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0509 0.0509
Echinococcus granulosus g protein coupled receptor 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1188 0.4847
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0497 0.1403
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0703 0.2049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0509 0.1483
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0196 0.0196
Echinococcus multilocularis serine:threonine protein kinase 38 0.0026 0.0126 0.0126
Brugia malayi Matrixin family protein 0.0194 0.2218 0.9045
Echinococcus granulosus geminin 0.0166 0.1874 0.546
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0019 0.004 0.0163
Brugia malayi phosphofructokinase 0.0111 0.1188 0.4847
Loa Loa (eye worm) hypothetical protein 0.0022 0.008 0.0326
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Brugia malayi sulfakinin receptor protein 0.0031 0.0196 0.08
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0187 0.0187
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1188 1
Brugia malayi Dopamine receptor protein 2 0.0031 0.0196 0.08
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0022 0.008 0.0233
Schistosoma mansoni histamine h1 receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0536 0.4512
Brugia malayi larval opioid receptor 0.0031 0.0196 0.08
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0413 0.1166
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0572
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0196 0.08
Brugia malayi Ras association domain family 1 isoform A 0.0018 0.0033 0.0134
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0196 0.0554
Brugia malayi Melatonin receptor type 1A 0.0031 0.0196 0.08
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0365 0.1489
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0058 0.0169
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus RNA directed DNA polymerase 0.0118 0.1279 0.3728
Brugia malayi mbt repeat family protein 0.0049 0.0413 0.1686
Schistosoma mansoni hypothetical protein 0.0072 0.0703 0.1984
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0187 0.0527
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0196 0.08
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0365 0.103
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0058 0.0058
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus somatostatin receptor 0.0031 0.0196 0.0572
Echinococcus multilocularis conserved hypothetical protein 0.0298 0.3521 0.3521
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.0126 0.0126
Echinococcus granulosus orexin receptor type 2 0.0031 0.0196 0.0572
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0196 0.0196
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Toxoplasma gondii AGC kinase 0.0026 0.0126 0.6774
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0399 0.1125
Loa Loa (eye worm) matrixin family protein 0.0194 0.2218 0.9045
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0026 0.0126 0.0516
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0026 0.0126 0.0368
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0018 0.0033 0.0033
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0196 0.0572
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0178 0.9525
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0085 0.086 0.2425
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.018 0.0226
Brugia malayi hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi neuropeptide F receptor 0.0031 0.0196 0.08
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.1188 0.1188
Schistosoma mansoni diacylglycerol kinase theta 0.0018 0.0033 0.0093
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0196 0.0196
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0365 0.1064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus granulosus neuropeptide receptor 0.0031 0.0196 0.0572
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0196 0.08
Onchocerca volvulus Matrilysin homolog 0.008 0.0804 0.277
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0196 0.0554
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0115 0.6355
Echinococcus multilocularis G protein coupled receptor 139 0.0031 0.0196 0.0196
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0033 0.0134
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0026 0.0126 0.0126
Schistosoma mansoni atypical protein kinase C 0.0044 0.0352 0.0993
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis peroxidasin 0.0084 0.0849 0.0849
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0126 0.0357
Onchocerca volvulus 0.0084 0.0849 0.2931
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Schistosoma mansoni glucose-6-phosphatase 0.03 0.3545 1
Loa Loa (eye worm) matrix metalloproteinase 0.008 0.0804 0.328
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.008 0.0804 0.2268
Echinococcus granulosus g protein coupled receptor 0.0031 0.0196 0.0572
Echinococcus granulosus Protein kinase C brain isozyme 0.0166 0.1871 0.5451
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0771 0.2176
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0196 0.0554
Schistosoma mansoni biogenic amine receptor 0.0031 0.0196 0.0554
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0115 0.6145
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0192 0.2196 0.2196
Schistosoma mansoni opsin-like receptor 0.0031 0.0196 0.0554
Onchocerca volvulus 0.0031 0.0196 0.0586
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0058 0.0169
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0413 0.1205
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.1021 0.2974
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0118 0.1279 0.1279
Brugia malayi Doublecortin family protein 0.002 0.0058 0.0236
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.1188 1
Echinococcus granulosus unc 13 munc13 0.0022 0.008 0.0233
Brugia malayi PHD-finger family protein 0.003 0.0178 0.0725
Echinococcus granulosus serotonin receptor 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Onchocerca volvulus Peroxidase homolog 0.0084 0.0849 0.2931
Brugia malayi p70 ribosomal S6 kinase beta 0.0026 0.0126 0.0516
Onchocerca volvulus 0.0114 0.1221 0.4266
Brugia malayi Protein kinase domain containing protein 0.0026 0.0126 0.0516
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0196 0.0572
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0196 0.0554
Brugia malayi hypothetical protein 0.002 0.0058 0.0236
Onchocerca volvulus Peroxidasin homolog 0.0084 0.0849 0.2931
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0196 0.0554
Trypanosoma brucei rac serine-threonine kinase, putative 0.0026 0.0126 0.1064
Echinococcus granulosus peregrin 0.003 0.0178 0.0518
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0365 0.103
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1188 0.3353
Loa Loa (eye worm) hypothetical protein 0.0136 0.1505 0.6138
Loa Loa (eye worm) hypothetical protein 0.008 0.0804 0.328
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0256 0.1043
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0058 0.3101
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi jmjC domain containing protein 0.0097 0.1021 0.4163
Echinococcus granulosus peroxidasin 0.0084 0.0849 0.2474
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Schistosoma mansoni biogenic amine receptor 0.0031 0.0196 0.0554
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Toxoplasma gondii 6-phosphofructokinase 0.003 0.018 0.9669
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0115 0.6145
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0093
Brugia malayi G protein-coupled receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1188 0.4847
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0018 0.0033 0.0134
Schistosoma mansoni myosin xvIII 0.0031 0.0196 0.0554
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0703 0.0703
Brugia malayi Dopamine receptor 0.0031 0.0196 0.08
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0196 0.08
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0196 0.0572
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0178 0.0178
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0196 0.0572
Onchocerca volvulus 0.0031 0.0196 0.0586
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0166 0.1871 0.1871
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Onchocerca volvulus 0.0031 0.0196 0.0586
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Toxoplasma gondii diacylglycerol kinase, putative 0.0018 0.0033 0.1766
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0196 0.0196
Brugia malayi Serotonin receptor 0.0031 0.0196 0.08
Schistosoma mansoni polycystin 1-related 0.002 0.0058 0.0163
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0196 0.0196
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0196 0.0554
Brugia malayi hypothetical protein 0.0072 0.0703 0.2868
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0196 0.0572
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0497 0.1449
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0196 0.0572
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.018 0.5
Schistosoma mansoni biogenic amine receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) hypothetical protein 0.0098 0.1021 0.4166
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0196 0.0554
Loa Loa (eye worm) AGC/PKN protein kinase 0.0026 0.0126 0.0516
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0033 0.0093
Onchocerca volvulus Chorion peroxidase homolog 0.0084 0.0849 0.2931
Loa Loa (eye worm) hypothetical protein 0.002 0.0058 0.0236
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) blistered cuticle protein 3 0.0084 0.0849 0.3463
Schistosoma mansoni rab6-interacting 0.002 0.0058 0.0163
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0187 1
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Brugia malayi RhoGAP domain containing protein 0.0018 0.0033 0.0134
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0196 0.0196
Brugia malayi Animal haem peroxidase family protein 0.0084 0.0849 0.3463
Brugia malayi GnHR receptor homolog 0.0031 0.0196 0.08
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Echinococcus granulosus N chimaerin 0.0018 0.0033 0.0096
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0196 0.0572
Echinococcus granulosus g protein coupled receptor 0.0031 0.0196 0.0572
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) doublecortin family protein 0.002 0.0058 0.0236
Echinococcus granulosus dnaJ subfamily C 6 0.0063 0.0586 0.1707
Echinococcus multilocularis RNA directed DNA polymerase 0.0118 0.1279 0.1279
Onchocerca volvulus 0.008 0.0804 0.277
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0196 0.0196
Echinococcus multilocularis peregrin 0.003 0.0178 0.0178
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0196 0.0196
Echinococcus granulosus Diacylglycerol kinase theta 0.0018 0.0033 0.0096
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni protein kinase C mu 0.0019 0.004 0.0112
Echinococcus granulosus fmrfamide receptor 0.0031 0.0196 0.0572
Brugia malayi Protein kinase domain containing protein 0.0026 0.0126 0.0516
Loa Loa (eye worm) matrixin family protein 0.0178 0.2018 0.8232
Echinococcus granulosus NDR protein kinase 0.0026 0.0126 0.0368
Schistosoma mansoni loxhd1 0.002 0.0058 0.0163
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0196 0.0572
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0196 0.0554
Echinococcus granulosus protein kinase C gamma type 0.0148 0.1645 0.4794
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni amine GPCR 0.0031 0.0196 0.0554
Brugia malayi diacylglycerol kinase 0.0018 0.0033 0.0134
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0058 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1188 0.3963
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1188 1
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.018 0.9669
Brugia malayi RhoGAP domain containing protein 0.0018 0.0033 0.0134
Onchocerca volvulus 0.0031 0.0196 0.0586
Schistosoma mansoni rac gtpase activating protein 0.0018 0.0033 0.0093
Brugia malayi hypothetical protein 0.0031 0.0196 0.08
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Brugia malayi 6-phosphofructokinase 0.0111 0.1188 0.4847
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0098 0.1021 0.4166
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0187 0.0527
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0019 0.004 0.0163
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis serotonin receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis neuropeptide receptor A26 0.0031 0.0196 0.0196
Entamoeba histolytica protein kinase, putative 0.0026 0.0126 0.0809
Schistosoma mansoni neuropeptide receptor 0.0031 0.0196 0.0554
Echinococcus granulosus serine:threonine protein kinase N2 0.0026 0.0126 0.0368
Echinococcus granulosus protein kinase c iota type 0.0044 0.0352 0.1026
Brugia malayi Matrixin family protein 0.008 0.0804 0.328
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0497 0.2028
Echinococcus granulosus RUN 0.002 0.0058 0.0169
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0026 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0084 0.0849 0.3463
Loa Loa (eye worm) animal heme peroxidase 0.0084 0.0849 0.3463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Schistosoma mansoni hypothetical protein 0.0166 0.1874 0.5285
Schistosoma mansoni lipoxygenase 0.0056 0.0509 0.1435
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0019 0.004 0.0163
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0033 0.0134
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0173 0.0503
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0256 0.0256
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0196 0.0572
Schistosoma mansoni hypothetical protein 0.002 0.0058 0.0163
Schistosoma mansoni opsin-like receptor 0.0031 0.0196 0.0554
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0187 0.0187
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0196 0.0572
Schistosoma mansoni hypothetical protein 0.0031 0.0196 0.0554
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.018 0.9669
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0134
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Brugia malayi hypothetical protein 0.0025 0.0115 0.0468
Onchocerca volvulus Peroxidasin homolog 0.0084 0.0849 0.2931
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0196 0.0586
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.08
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0022 0.008 0.008
Brugia malayi Protein kinase c protein 2 0.0141 0.1559 0.6357
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.1263 0.5152
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.018 1
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0126 0.0026
Brugia malayi Serotonin receptor 0.0031 0.0196 0.08
Schistosoma mansoni hypothetical protein 0.0106 0.1123 0.3167
Schistosoma mansoni peroxidasin 0.0084 0.0849 0.2395
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0196 0.0572
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0536 0.1563
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0413 0.0413
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0026 0.0126 0.0368
Loa Loa (eye worm) MBCTL1 0.0055 0.0497 0.2028
Entamoeba histolytica hypothetical protein 0.0072 0.0703 0.58

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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