Detailed information for compound 843402

Basic information

Technical information
  • TDR Targets ID: 843402
  • Name: N-(2,4-dimethoxyphenyl)-2-(8-methyl-4H-chrome no[3,4-d]pyrazol-1-yl)acetamide
  • MW: 379.409 | Formula: C21H21N3O4
  • H donors: 1 H acceptors: 2 LogP: 2.75 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)ccc1NC(=O)Cn1ncc2c1c1cc(C)ccc1OC2
  • InChi: 1S/C21H21N3O4/c1-13-4-7-18-16(8-13)21-14(12-28-18)10-22-24(21)11-20(25)23-17-6-5-15(26-2)9-19(17)27-3/h4-10H,11-12H2,1-3H3,(H,23,25)
  • InChiKey: NUNHFNNKSSHWSZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2,4-dimethoxyphenyl)-2-(8-methyl-4H-chromeno[3,4-d]pyrazol-1-yl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0554 0.4241
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0558 0.0558
Trypanosoma brucei glucose transporter 1E 0.0031 0.0579 0.1737
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0771 0.3059
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.2508 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.058 0.0414
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0021 0.0321 0.0138
Echinococcus multilocularis 0.0021 0.0321 0.0293
Schistosoma mansoni hypothetical protein 0.0075 0.1616 0.1722
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.0131 0.016
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2229 0.2336
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0609 0.0601
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0292 0.6712 1
Echinococcus multilocularis caspase 8 0.0018 0.025 0.0216
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0371 0.0363
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0371 0.062
Schistosoma mansoni lamin 0.0028 0.0507 0.054
Brugia malayi hypothetical protein 0.0021 0.0321 0.0524
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0771 0.0987
Schistosoma mansoni smad1 5 8 and 0.0009 0.0048 0.0051
Loa Loa (eye worm) hypothetical protein 0.0041 0.0799 0.1441
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0321 0.023
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Echinococcus multilocularis cpg binding protein 0.0062 0.1299 0.134
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.025 0.0978
Brugia malayi follicle stimulating hormone receptor 0.023 0.5259 1
Chlamydia trachomatis protoporphyrinogen oxidase 0.0021 0.0321 0.4927
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.058 0.0414
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0771 0.0987
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Schistosoma mansoni amine oxidase 0.0021 0.0321 0.0342
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.2508 0.3857
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.058 0.057
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0173 0.0672
Loa Loa (eye worm) acetyltransferase 0.0144 0.323 0.6106
Brugia malayi beta-lactamase family protein 0.004 0.0771 0.1387
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0673 0.2142
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0173 0.0173
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0304 0.0216
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.1072 0.1097
Trypanosoma brucei metacaspase MCA3 0.0018 0.025 0.0329
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0771 0.256
Echinococcus multilocularis solute carrier family 22 0.0014 0.0173 0.0134
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0304 0.1211
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0579 0.2292
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0321 0.0633
Plasmodium falciparum hexose transporter 0.0101 0.2229 0.2229
Brugia malayi CXXC zinc finger family protein 0.0059 0.1221 0.2251
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.1212 0.9916
Toxoplasma gondii ABC1 family protein 0.004 0.0771 0.0929
Echinococcus multilocularis lamin 0.0028 0.0507 0.0491
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0018 0.025 0.0216
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0371 0.0768
Entamoeba histolytica hypothetical protein 0.0023 0.0371 0.1478
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.2508 0.4721
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0558 0.0558
Leishmania major glucose transporter, lmgt2 0.0031 0.0579 0.1575
Echinococcus multilocularis solute carrier family 22 0.0014 0.0173 0.0134
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.2508 0.2672
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.1072 0.1097
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.323 0.3407
Loa Loa (eye worm) hypothetical protein 0.0032 0.058 0.1021
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2229 0.2336
Plasmodium falciparum metacaspase-like protein 0.0018 0.025 0.025
Echinococcus granulosus General substrate transporter 0.0087 0.1892 0.1975
Loa Loa (eye worm) hypothetical protein 0.004 0.0771 0.1387
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0173 0.0125
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.323 0.3441
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0558 0.2227
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.2229 0.8885
Schistosoma mansoni cpg binding protein 0.0059 0.1221 0.13
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0321 0.0293
Schistosoma mansoni glucose transporter 0.0014 0.0173 0.0184
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0035 0.0038
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0173 0.0134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.015 0.058
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0181 0.0142
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0558 0.0599
Mycobacterium ulcerans lipase LipD 0.004 0.0771 0.1028
Loa Loa (eye worm) hypothetical protein 0.0025 0.042 0.0714
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0173 0.0241
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0558 0.0392
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0173 0.0672
Echinococcus granulosus dnaJ subfamily B 0.0405 0.9386 1
Mycobacterium leprae Probable lipase LipE 0.004 0.0771 0.2167
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.058 0.0618
Trypanosoma brucei metacaspase MCA2 0.0018 0.025 0.0329
Trypanosoma cruzi metacaspase, putative 0.0018 0.025 0.0329
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0173 0.0241
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.2747 0.2891
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0771 0.0821
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0173 0.0125
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.323 0.6106
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0173 0.0241
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0554 0.2195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0835 0.3314
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.3135 0.3306
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.2277 0.4278
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0609 0.1077
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0021 0.0321 0.0348
Loa Loa (eye worm) hypothetical protein 0.0158 0.3553 0.6727
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0949 0.1011
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.1072 0.1142
Schistosoma mansoni ap endonuclease 0.002 0.0304 0.0324
Echinococcus granulosus solute carrier family 22 0.0014 0.0173 0.0134
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0835 0.3314
Plasmodium falciparum metacaspase 1 0.0018 0.025 0.025
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0579 0.1737
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0021 0.0321 0.0342
Echinococcus multilocularis General substrate transporter 0.0087 0.1892 0.1975
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0173 0.0672
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0673 0.1943
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.1072 0.385
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0173 0.0672
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0558 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.2747 0.2891
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0181 0.0142
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0524 0.051
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1072 0.4263
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0371 0.0846
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Trypanosoma cruzi metacaspase, putative 0.0018 0.025 0.0329
Schistosoma mansoni hypothetical protein 0.0033 0.0609 0.0649
Schistosoma mansoni lamin 0.0028 0.0507 0.054
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0949 0.173
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0558 0.2211
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0164 0.3713 0.3602
Brugia malayi Sugar transporter family protein 0.0101 0.2229 0.4186
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.2747 0.4251
Schistosoma mansoni intermediate filament proteins 0.0028 0.0507 0.054
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Toxoplasma gondii facilitative glucose transporter GT1 0.0101 0.2229 0.3196
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0609 0.1077
Mycobacterium tuberculosis Conserved protein 0.004 0.0771 0.0987
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0771 0.3059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0494 0.0857
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.058 0.058
Plasmodium vivax hypothetical protein, conserved 0.0018 0.025 0.0078
Brugia malayi 6-phosphofructokinase 0.0113 0.2508 0.4721
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0371 0.0307
Echinococcus multilocularis muscleblind protein 0.0158 0.3553 0.3754
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0558 0.0599
Trypanosoma cruzi metacaspase, putative 0.0018 0.025 0.0329
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.2508 1
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0771 0.3059
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.058 0.058
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.058 0.1743
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.2508 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.025 0.0978
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0771 0.3059
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.1072 0.1097
Onchocerca volvulus 0.0028 0.0507 0.3183
Brugia malayi hypothetical protein 0.0014 0.0173 0.0241
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.1072 0.3493
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0579 0.2292
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0259 0.0406
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.2747 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.015 0.058
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.058 0.2297
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.2747 0.4012
Mycobacterium leprae conserved hypothetical protein 0.004 0.0771 0.2167
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0554 0.0972
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.058 0.1021
Loa Loa (eye worm) hypothetical protein 0.0103 0.2277 0.4278
Brugia malayi Cell death protein 3 precursor 0.0058 0.1212 0.2234
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Plasmodium vivax hypothetical protein, conserved 0.004 0.0771 0.0608
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0021 0.0321 0.015
Schistosoma mansoni glucose transport protein 0.0101 0.2229 0.2375
Plasmodium falciparum mitogen-activated protein kinase 2 0.0164 0.3713 0.3713
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.025 0.0978
Schistosoma mansoni sugar transporter 0.0014 0.0173 0.0184
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0771 0.1387
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0771 0.3059
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.058 0.058
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0554 0.221
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0835 0.0673
Schistosoma mansoni protein kinase 0.0032 0.058 0.0618
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.2508 0.2635
Schistosoma mansoni protein kinase 0.0032 0.058 0.0618
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.1505 0.2796
Brugia malayi beta-lactamase family protein 0.004 0.0771 0.1387
Echinococcus multilocularis solute carrier family 22 0.0014 0.0173 0.0134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.015 0.058
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0673 0.0778
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Loa Loa (eye worm) hypothetical protein 0.0021 0.0321 0.0524
Loa Loa (eye worm) hypothetical protein 0.0013 0.0148 0.0192
Echinococcus multilocularis GPCR, family 2 0.0033 0.0609 0.0601
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.058 0.058
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0304 0.0508
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0579 0.1737
Schistosoma mansoni smad 0.0009 0.0048 0.0051
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0579 0.2292
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0304 0.1194
Brugia malayi Sugar transporter family protein 0.0014 0.0173 0.0241
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0558 0.4286
Schistosoma mansoni cpg binding protein 0.0062 0.1299 0.1384
Trypanosoma brucei metacaspase 5, putative 0.0018 0.025 0.0329
Onchocerca volvulus 0.004 0.0771 0.5706
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Trypanosoma brucei protein kinase, putative 0.0052 0.1072 0.385
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0609 0.0601
Loa Loa (eye worm) hypothetical protein 0.004 0.0771 0.1387
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.2508 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0304 0.056
Brugia malayi major facilitator superfamily protein 0.0014 0.0173 0.0241
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0173 0.0241
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0799 0.0804
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.029 0.0193
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0304 0.0491
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0265 0.0232
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.2277 0.4278
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0799 0.0804
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.058 0.057
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0673 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0173 0.0672
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2229 0.2336
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Loa Loa (eye worm) beta-lactamase 0.004 0.0771 0.1387
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.2747 0.4001
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.058 0.057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.058 0.057
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0371 0.1461
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.2508 1
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.2508 0.9071
Schistosoma mansoni caspase-3 (C14 family) 0.0018 0.025 0.0266
Toxoplasma gondii protein kinase, putative 0.0287 0.6606 1
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.9386 1
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.2508 0.2635
Echinococcus multilocularis lamin dm0 0.0028 0.0507 0.0491
Brugia malayi beta-lactamase 0.004 0.0771 0.1387
Schistosoma mansoni cpg binding protein 0.0062 0.1299 0.1384
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.2508 0.3651
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1072 0.4263
Loa Loa (eye worm) hypothetical protein 0.003 0.0554 0.0972
Echinococcus granulosus solute carrier family 22 0.0014 0.0173 0.0134
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0181 0.0142
Entamoeba histolytica protein kinase, putative 0.0032 0.058 0.2312
Echinococcus granulosus caspase 0.0018 0.025 0.0216
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0371 0.0424
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0949 0.1011
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.2934 0.5538
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0507 0.088
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0101 0.2229 0.2336
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0554 0.1191
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.2277 0.4278
Brugia malayi Muscleblind-like protein 0.0158 0.3553 0.6727
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0173 0.0672
Entamoeba histolytica hypothetical protein 0.0075 0.1616 0.6443
Brugia malayi hypothetical protein 0.0075 0.1616 0.3009
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0021 0.0321 0.0293
Loa Loa (eye worm) hypothetical protein 0.0018 0.025 0.0388
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0558 0.2211
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.2508 0.2672
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.2934 0.5538
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.025 0.0119
Echinococcus granulosus caspase 2 0.0058 0.1212 0.1246
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.058 0.0633
Schistosoma mansoni smad1 5 8 and 0.0009 0.0048 0.0051
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0371 0.0424
Schistosoma mansoni sugar transporter 0.0014 0.0173 0.0184
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0371 0.0346
Plasmodium falciparum protein kinase 7 0.0287 0.6606 0.6606
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.2542 0.3682
Brugia malayi hypothetical protein 0.0041 0.0799 0.1441
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.2508 0.4721
Echinococcus multilocularis caspase 2 0.0058 0.1212 0.1246
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0554 0.0972
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0579 0.1737
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0173 0.0672
Trypanosoma brucei glucose transporter 2A 0.0031 0.0579 0.1737
Schistosoma mansoni smad1 5 8 and 0.0009 0.0048 0.0051
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0554 0.0591
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.058 0.1021
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0304 0.0491
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0558 0.2211
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0771 0.0987
Schistosoma mansoni hypothetical protein 0.0166 0.376 0.4006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0554 0.0543
Loa Loa (eye worm) hypothetical protein 0.004 0.0771 0.1387
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Entamoeba histolytica protein kinase, putative 0.0032 0.058 0.2312
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Plasmodium vivax hexose transporter 0.0101 0.2229 0.2092
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0579 0.1737
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0024 0.0405 0.0361
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0949 0.1011
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0018 0.025 0.0388
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0673 0.2142
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0371 0.0371
Schistosoma mansoni hypothetical protein 0.0033 0.0609 0.0649
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.025 0.0266
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0558 0.2211
Schistosoma mansoni hypothetical protein 0.0041 0.0799 0.0851
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.015 0.058
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.1072 0.385
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.025 0.0119
Echinococcus granulosus lamin 0.0028 0.0507 0.0491
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.058 0.1021
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0371 0.0395
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.058 0.057
Schistosoma mansoni protein kinase 0.0032 0.058 0.0618
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.025 0.0329
Onchocerca volvulus 0.004 0.0771 0.5706
Echinococcus multilocularis muscleblind protein 1 0.0158 0.3553 0.3754
Schistosoma mansoni sugar transporter 0.0014 0.0173 0.0184
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0304 0.0274
Schistosoma mansoni hypothetical protein 0.0033 0.0609 0.0649
Loa Loa (eye worm) follicle stimulating hormone receptor 0.023 0.5259 1
Leishmania major glucose transporter, lmgt1 0.0031 0.0579 0.1575
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0771 0.1028
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0196 0.0284
Plasmodium vivax CDK-related protein kinase 6, putative 0.0431 1 1
Brugia malayi SWIRM domain containing protein 0.0021 0.0321 0.0524
Loa Loa (eye worm) phosphofructokinase 0.0113 0.2508 0.4721
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Loa Loa (eye worm) hypothetical protein 0.0033 0.0609 0.1077
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.025 0.0119
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0771 0.0774
Echinococcus granulosus GPCR family 2 0.0033 0.0609 0.0601
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0554 0.0591
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.1072 0.1966
Brugia malayi amine oxidase, flavin-containing family protein 0.0021 0.0321 0.0524
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0265 0.0417
Brugia malayi 6-phosphofructokinase 0.0113 0.2508 0.4721
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0771 0.0987
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0771 0.256
Mycobacterium ulcerans monoamine oxidase 0.0021 0.0321 0.0348
Loa Loa (eye worm) hypothetical protein 0.0013 0.0148 0.0192
Leishmania major hypothetical protein, conserved 0.004 0.0771 0.2322
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0949 0.0965
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0018 0.025 0.0216
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0304 0.0323
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0304 0.0274
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0558 1
Mycobacterium tuberculosis Conserved protein 0.004 0.0771 0.0987
Loa Loa (eye worm) hypothetical protein 0.004 0.0771 0.1387
Loa Loa (eye worm) hypothetical protein 0.0023 0.0371 0.062
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0673 0.0673
Loa Loa (eye worm) sugar transporter 0.0101 0.2229 0.4186
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0771 0.1028
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0558 0.2211
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0673 0.2142
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.1616 0.1679
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2229 0.2336
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.025 0.0266
Brugia malayi intermediate filament protein 0.0028 0.0507 0.088
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.015 0.058
Echinococcus multilocularis protoporphyrinogen oxidase 0.0021 0.0321 0.0293
Brugia malayi hypothetical protein 0.0014 0.0173 0.0241
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0173 0.0125
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Loa Loa (eye worm) hypothetical protein 0.0028 0.0507 0.088
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2229 0.2336
Echinococcus granulosus lamin dm0 0.0028 0.0507 0.0491
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.025 0.0978
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0949 0.0965
Trypanosoma brucei Metacaspase-4 0.0018 0.025 0.0329
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.5804 0.93
Schistosoma mansoni sugar transporter 0.0014 0.0173 0.0184
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0771 0.0987
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0771 0.0774
Entamoeba histolytica hypothetical protein 0.0075 0.1616 0.6443
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0292 0.6712 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0321 0.0293
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Loa Loa (eye worm) hypothetical protein 0.0021 0.0321 0.0524
Trichomonas vaginalis esterase, putative 0.004 0.0771 0.3059
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0371 0.599
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Loa Loa (eye worm) hypothetical protein 0.0021 0.0321 0.0524
Mycobacterium tuberculosis Conserved protein 0.004 0.0771 0.0987
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0021 0.0321 0.0342
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.1072 1
Brugia malayi MH2 domain containing protein 0.0131 0.2934 0.5538
Leishmania major protein kinase, putative 0.0032 0.058 0.1581
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0371 0.0395
Onchocerca volvulus 0.0041 0.0799 0.5972
Mycobacterium ulcerans hypothetical protein 0.004 0.0771 0.1028
Loa Loa (eye worm) hypothetical protein 0.0021 0.0321 0.0524
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.029 0.0193
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0173 0.0184
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.2747 0.4012
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.2508 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.1072 0.1398
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0305 0.1198
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2229 0.2336
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.025 0.0978
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0579 0.2292
Echinococcus granulosus caspase 8 0.0018 0.025 0.0216
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0579 0.2292
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0507 0.088
Trichomonas vaginalis helicase, putative 0.0013 0.015 0.058
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0371 0.0346
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.2508 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0751 0.2996
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Schistosoma mansoni hypothetical protein 0.0405 0.9386 1
Echinococcus multilocularis solute carrier family 22 0.0014 0.0173 0.0134
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0771 0.0987
Schistosoma mansoni hypothetical protein 0.0101 0.2229 0.2375
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.058 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.1072 0.385
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1072 0.4263
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0835 0.1028
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.025 0.0978
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0751 0.0751
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0579 0.2292
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.1212 0.1291
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.2508 1
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0771 0.0987
Echinococcus granulosus solute carrier family 22 0.0014 0.0173 0.0134
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.2747 0.2927
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0751 0.6433
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Leishmania major glucose transporter, lmgt3 0.0031 0.0579 0.1575
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.025 0.0329
Toxoplasma gondii exonuclease III APE 0.002 0.0304 0.0203
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.015 0.058
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.058 0.0633
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0242 0.0296
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.058 0.0414
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.1072 0.385
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0579 0.2292
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0579 0.1737
Loa Loa (eye worm) hypothetical protein 0.0021 0.0321 0.0524
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0609 0.1077
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.058 0.0633
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0181 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.025 0.0978
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Plasmodium falciparum protoporphyrinogen oxidase 0.0021 0.0321 0.0321
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0196 0.0284
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0558 0.2211
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.1072 0.385
Onchocerca volvulus 0.004 0.0771 0.5706
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0173 0.0134
Loa Loa (eye worm) hypothetical protein 0.004 0.0771 0.1387
Brugia malayi phosphofructokinase 0.0113 0.2508 0.4721
Schistosoma mansoni hypothetical protein 0.0033 0.0609 0.0649
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0949 0.0965
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0835 0.1028
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0265 0.0232
Schistosoma mansoni ap endonuclease 0.002 0.0304 0.0324
Loa Loa (eye worm) hypothetical protein 0.004 0.0771 0.1387
Trypanosoma brucei glucose transporter, putative 0.0031 0.0579 0.1737
Loa Loa (eye worm) hypothetical protein 0.0071 0.1505 0.2796
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0173 0.0134
Loa Loa (eye worm) sugar transporter 0.0014 0.0173 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0173 0.0672
Schistosoma mansoni glucose transport protein 0.0101 0.2229 0.2375
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.058 0.057
Brugia malayi Sugar transporter family protein 0.0014 0.0173 0.0241
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.2747 0.4012
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0524 0.051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0304 0.056
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.016 0.012
Leishmania major metacaspase, putative 0.0018 0.025 0.0298
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0304 0.0883
Brugia malayi hypothetical protein 0.0014 0.0173 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0321 0.0633
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0173 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.015 0.058
Brugia malayi MAP kinase sur-1 0.0052 0.1072 0.1966
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.1072 0.3493
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0304 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0304 0.1194
Loa Loa (eye worm) hypothetical protein 0.003 0.0554 0.0972
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0021 0.0321 0.015
Schistosoma mansoni hypothetical protein 0.0071 0.1505 0.1603
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.1072 0.1097
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.1221 0.2251
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0949 0.0965
Loa Loa (eye worm) hypothetical protein 0.0021 0.0321 0.0524
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0321 0.015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.015 0.058
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.1616 0.1679
Schistosoma mansoni amine oxidase 0.0021 0.0321 0.0342
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0949 0.173
Echinococcus multilocularis geminin 0.0166 0.376 0.3975
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0321 0.0321
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.058 0.0414
Leishmania major UDP-galactopyranose mutase 0.0021 0.0321 0.0574
Entamoeba histolytica hypothetical protein 0.0075 0.1616 0.6443
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.2508 1
Mycobacterium ulcerans sugar transporter 0.0014 0.0173 0.0125
Mycobacterium ulcerans dehydrogenase 0.0021 0.0321 0.0348
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0554 0.0543
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Echinococcus granulosus geminin 0.0166 0.376 0.3975
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.2508 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.1212 0.2234
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.015 0.058
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0609 0.0601
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0835 0.0843
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0304 0.056
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0579 0.1575
Echinococcus multilocularis caspase 0.0018 0.025 0.0216
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0558 0.0392
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0558 0.2211
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.2508 1
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.2747 0.2927
Loa Loa (eye worm) hypothetical protein 0.0158 0.3553 0.6727
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0271 0.6228 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0507 0.088
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0304 0.0304
Onchocerca volvulus 0.0028 0.0507 0.3183
Plasmodium vivax metacaspase 1, putative 0.0018 0.025 0.0078
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0771 0.1387
Schistosoma mansoni hypothetical protein 0.0166 0.376 0.4006
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.016 0.012
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0371 0.0201
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.058 0.057
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0321 0.015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0609 0.0601
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0558 0.0599
Loa Loa (eye worm) hypothetical protein 0.0014 0.016 0.0215
Trypanosoma cruzi metacaspase, putative 0.0018 0.025 0.0329
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0371 0.2198
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.2772 0.2953
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.058 0.057
Trypanosoma brucei metacaspase 0.0018 0.025 0.0329
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0771 0.256
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0173 0.0241
Mycobacterium ulcerans beta-lactamase 0.004 0.0771 0.1028
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0181 0.0142
Trypanosoma cruzi hexose transporter 0.0031 0.0579 0.1737
Echinococcus granulosus intermediate filament protein 0.0028 0.0507 0.0491
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0673 0.1943
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2229 0.2336
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0304 0.1454
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0321 0.0244
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0321 0.0244
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.0048 0.0051
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0371 0.0846
Brugia malayi major facilitator superfamily protein 0.0014 0.0173 0.0241
Echinococcus granulosus cpg binding protein 0.0062 0.1299 0.134
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0173 0.0672
Entamoeba histolytica hypothetical protein 0.0075 0.1616 0.6443
Schistosoma mansoni glucose transport protein 0.0101 0.2229 0.2375
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0579 0.1737
Schistosoma mansoni Smad4 0.0009 0.0048 0.0051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0771 0.0821
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0304 0.0133
Brugia malayi Cam kinase protein 1 0.0032 0.058 0.1021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0173 0.0241
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.1616 0.1722
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0558 0.1936
Echinococcus granulosus muscleblind protein 0.0158 0.3553 0.3754
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0164 0.3713 0.5503
Onchocerca volvulus 0.0021 0.0321 0.1411
Echinococcus multilocularis musashi 0.0028 0.0507 0.0491
Mycobacterium ulcerans oxidoreductase 0.0021 0.0321 0.0348
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1072 0.4263
Onchocerca volvulus 0.0059 0.1221 1
Echinococcus granulosus solute carrier family 22 0.0014 0.0173 0.0134

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.