TDR Targets

Basic information

Technical information

TDR Targets ID: 863784
Name: EU-0064033
MW: 457.518 | Formula: C23H24FN3O4S
H donors: 2 H acceptors: 5 LogP: 3.47 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CC1CCCN(C1)S(=O)(=O)c1ccc2c(c1)c(cc(n2)O)C(=O)NCc1ccc(cc1)F
InChi: 1S/C23H24FN3O4S/c1-15-3-2-10-27(14-15)32(30,31)18-8-9-21-19(11-18)20(12-22(28)26-21)23(29)25-13-16-4-6-17(24)7-5-16/h4-9,11-12,15H,2-3,10,13-14H2,1H3,(H,25,29)(H,26,28)
InChiKey: FTHTWIBDRCMBJP-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-(4-fluorobenzyl)-2-keto-6-[(3-methyl-1-piperidyl)sulfonyl]-1H-quinoline-4-carboxamide
N-[(4-fluorophenyl)methyl]-6-(3-methylpiperidin-1-yl)sulfonyl-2-oxo-1H-quinoline-4-carboxamide
N-[(4-fluorophenyl)methyl]-6-[(3-methyl-1-piperidyl)sulfonyl]-2-oxo-1H-quinoline-4-carboxamide
N-[(4-fluorophenyl)methyl]-6-[(3-methyl-1-piperidinyl)sulfonyl]-2-oxo-1H-quinoline-4-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	Mitogen-activated protein kinase 10, putative	0.0017	0.0039	1
Schistosoma mansoni	talin 2	0.0013	0.0006	0.0006
Echinococcus granulosus	Pleckstrin y	0.0013	0.0006	0.0006
Loa Loa (eye worm)	CDC7 protein kinase	0.1106	0.9641	0.9641
Echinococcus multilocularis	unc 112 protein	0.0013	0.0006	0.0006
Brugia malayi	Protein kinase domain containing protein	0.0017	0.0039	0.0039
Schistosoma mansoni	protein kinase	0.0015	0.0022	0.0022
Echinococcus multilocularis	myosin viia	0.0013	0.0006	0.0006
Echinococcus multilocularis	protein tyrosine phosphatase, non receptor type	0.0013	0.0006	0.0006
Entamoeba histolytica	protein kinase domain containing protein	0.0015	0.0022	0.0441
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Loa Loa (eye worm)	MyTH4 domain-containing protein	0.0013	0.0006	0.0006
Schistosoma mansoni	serine/threonine protein kinase	0.0017	0.0039	0.004
Trichomonas vaginalis	AGC family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	MyTH4 domain containing protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	FERM domain containing protein 3	0.0013	0.0006	0.0006
Echinococcus granulosus	cyclin dependent kinase 9	0.0055	0.037	0.0374
Echinococcus multilocularis	talin 2	0.0013	0.0006	0.0006
Trypanosoma brucei	protein kinase, putative	0.0017	0.0039	1
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Schistosoma mansoni	merlin/moesin/ezrin/radixin	0.0013	0.0006	0.0006
Echinococcus granulosus	merlin:moesin:ezrin:radixin	0.0013	0.0006	0.0006
Onchocerca volvulus		0.1106	0.9641	1
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus granulosus	FERM central domain	0.0013	0.0006	0.0006
Onchocerca volvulus		0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	serine:threonine protein kinase NLK	0.0017	0.0039	0.004
Leishmania major	mitogen-activated protein kinase, putative,map kinase-like protein	0.0017	0.0039	1
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	GH28553p	0.0013	0.0006	0.0006
Echinococcus granulosus	Cell division cycle 2 protein kinase	0.0017	0.0039	0.004
Onchocerca volvulus		0.1106	0.9641	1
Schistosoma mansoni	kinase	0.0055	0.037	0.0374
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0015	0.0022	0.4777
Echinococcus granulosus	serine:threonine protein kinase NLK	0.0017	0.0039	0.004
Echinococcus granulosus	myosin viia	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus granulosus	talin 2	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Schistosoma mansoni	serine/threonine protein kinase	0.1106	0.9641	0.9757
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Plasmodium falciparum	MO15-related protein kinase	0.0017	0.0039	1
Brugia malayi	Ferm domain	0.0013	0.0006	0.0006
Echinococcus granulosus	FERM domain containing protein 3	0.0013	0.0006	0.0006
Brugia malayi	Ferm domain	0.0013	0.0006	0.0006
Echinococcus granulosus	FERM domain containing protein 3	0.0013	0.0006	0.0006
Echinococcus multilocularis	Cell division cycle 2 protein kinase	0.0017	0.0039	0.004
Echinococcus granulosus	H17g protein tegumental antigen	0.0013	0.0006	0.0006
Schistosoma mansoni	merlin/moesin/ezrin/radixin	0.0013	0.0006	0.0006
Echinococcus granulosus	unc 112 protein	0.0013	0.0006	0.0006
Echinococcus multilocularis	Pleckstrin y	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Onchocerca volvulus		0.0013	0.0006	0.0006
Echinococcus multilocularis	FERM central domain	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Brugia malayi	Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 4-like	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0017	0.0039	1
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Brugia malayi	Unc-112 related protein.	0.0013	0.0006	0.0006
Trichomonas vaginalis	protein kinase atmrk1, putative	0.0017	0.0039	0.0035
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	haspin protein kinase	0.0017	0.0039	0.0039
Trypanosoma brucei	Mitogen-activated protein kinase 10, putative	0.0017	0.0039	1
Trichomonas vaginalis	AGC family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	Protein kinase domain containing protein	0.1106	0.9641	0.9641
Loa Loa (eye worm)	neurofibromin 2 isoform 8	0.0013	0.0006	0.0006
Echinococcus granulosus	radixin	0.0013	0.0006	0.0006
Echinococcus granulosus	mitogen activated protein kinase 15	0.0017	0.0039	0.004
Echinococcus multilocularis		0.0013	0.0006	0.0006
Brugia malayi	cyclin-dependent kinase 9	0.0055	0.037	0.037
Schistosoma mansoni	Band 4.1-like protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0213	0.1768	0.1768
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0013	0.0006	0.0006
Schistosoma mansoni	talin	0.0013	0.0006	0.0006
Plasmodium vivax	serine/threonine protein kinase KIN, putative	0.0017	0.0039	0.5
Brugia malayi	protein-tyrosine-phosphatase	0.0013	0.0006	0.0006
Brugia malayi	Cell division protein kinase 2	0.0017	0.0039	0.0039
Giardia lamblia	Kinase, CDC7	0.1106	0.9641	1
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus granulosus	ezrin	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus multilocularis	SPRY domain containing protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	AGC family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	Moesin/ezrin/radixin homolog 1	0.0013	0.0006	0.0006
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	moesin	0.0013	0.0006	0.0006
Trypanosoma cruzi	Mitogen-activated protein kinase 10, putative	0.0017	0.0039	1
Loa Loa (eye worm)	AGC/PDK1 protein kinase	0.0017	0.0039	0.0039
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus granulosus	protein tyrosine phosphatase non receptor type	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	CMGC/CDK/CRK7 protein kinase	0.0017	0.0039	0.0039
Echinococcus granulosus	SPRY domain containing protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	AGC family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	hypothetical protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	AGC family protein kinase	0.0017	0.0039	0.0035
Schistosoma mansoni	serine/threonine kinase	0.0017	0.0039	0.004
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	Ezrin radixin moesin ERM	0.0013	0.0006	0.0006
Echinococcus multilocularis	FERM domain containing protein 3	0.0013	0.0006	0.0006
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	cyclin dependent kinase 9	0.0055	0.037	0.0374
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	merlin:moesin:ezrin:radixin	0.0013	0.0006	0.0006
Echinococcus multilocularis	talin	0.0013	0.0006	0.0006
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Onchocerca volvulus	Tyrosine kinase homolog	0.0212	0.1759	0.1825
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Onchocerca volvulus		0.0013	0.0006	0.0006
Loa Loa (eye worm)	TK/FAK protein kinase	0.1147	1	1
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	cyclin dependent kinase 9	0.0063	0.044	0.0445
Trichomonas vaginalis	G protein-coupled receptor kinase, putative	0.0017	0.0039	0.0035
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus granulosus	cyclin dependent kinase 9	0.0063	0.044	0.0445
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Schistosoma mansoni	tyrosine kinase	0.0014	0.001	0.001
Trichomonas vaginalis	CMGC family protein kinase	0.1106	0.9641	1
Onchocerca volvulus		0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus granulosus	protein 4.1	0.0013	0.0006	0.0006
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0015	0.0022	0.0022
Trichomonas vaginalis	serine/threonine kinase, putative	0.0017	0.0039	0.0035
Trichomonas vaginalis	CMGC family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	neurofibromatosis homolog protein 1	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	CMGC family protein kinase	0.0017	0.0039	0.0035
Echinococcus granulosus	activin receptor type	0.0015	0.0022	0.0022
Onchocerca volvulus	Putative 4.1 G protein	0.0013	0.0006	0.0006
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0013	0.0006	0.0006
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0013	0.0006	0.0006
Schistosoma mansoni	protein kinase	0.0017	0.0039	0.004
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0015	0.0022	0.0022
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Schistosoma mansoni	protein kinase	0.0015	0.0022	0.0022
Schistosoma mansoni	merlin/moesin/ezrin/radixin	0.0013	0.0006	0.0006
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Schistosoma mansoni	protein kinase	0.0015	0.0022	0.0022
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Entamoeba histolytica	cell division protein kinase 2, putative	0.0017	0.0039	0.0923
Leishmania major	serine/threonine kinase-like protein, putative	0.0017	0.0039	1
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0017	0.0039	0.0039
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus granulosus	FERM domain containing protein 5	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	CDC7 cell division cycle 7	0.1106	0.9641	0.9757
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Schistosoma mansoni	hypothetical protein	0.0013	0.0006	0.0006
Plasmodium vivax	cyclin dependent kinase 7 (cdk7), putative	0.0017	0.0039	0.5
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Onchocerca volvulus		0.0013	0.0006	0.0006
Trichomonas vaginalis	AGC family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	ezrin	0.0013	0.0006	0.0006
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	protein tyrosine kinase	0.1133	0.9882	1
Entamoeba histolytica	protein kinase domain containing protein	0.0055	0.037	1
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Entamoeba histolytica	protein kinase domain containing protein	0.0017	0.0039	0.0923
Trichomonas vaginalis	CMGC family protein kinase	0.1106	0.9641	1
Schistosoma mansoni	tyrosine kinase	0.1133	0.9882	1
Brugia malayi	GRP1 binding protein	0.0013	0.0006	0.0006
Echinococcus granulosus	protein tyrosine kinase	0.1133	0.9882	1
Trichomonas vaginalis	CMGC family protein kinase	0.0017	0.0039	0.0035
Echinococcus multilocularis	FERM central domain	0.0013	0.0006	0.0006
Brugia malayi	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus multilocularis	radixin	0.0013	0.0006	0.0006
Echinococcus multilocularis	activin receptor type	0.0015	0.0022	0.0022
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0015	0.0022	0.5
Trichomonas vaginalis	CMGC family protein kinase	0.1106	0.9641	1
Brugia malayi	cyclin-dependent kinase 7 homolog	0.0017	0.0039	0.0039
Schistosoma mansoni	Radixin	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0258	0.2165	0.2165
Echinococcus multilocularis	SPRY domain containing protein	0.0013	0.0006	0.0006
Trichomonas vaginalis	CMGC family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	FERM domain	0.0013	0.0006	0.0006
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0013	0.0006	0.0006
Echinococcus multilocularis	FERM domain containing protein 5	0.0013	0.0006	0.0006
Echinococcus granulosus	Ezrin radixin moesin ERM	0.0013	0.0006	0.0006
Schistosoma mansoni	serine/threonine protein kinase	0.0055	0.037	0.0374
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Echinococcus granulosus	talin	0.0013	0.0006	0.0006
Echinococcus granulosus	SPRY domain containing protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus granulosus	FERM domain containing protein 5	0.0013	0.0006	0.0006
Echinococcus multilocularis	H17g protein, tegumental antigen	0.0013	0.0006	0.0006
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0015	0.0022	0.4777
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0015	0.0022	0.0022
Echinococcus granulosus	SPRY domain containing protein	0.0013	0.0006	0.0006
Brugia malayi	Talin 1	0.0013	0.0006	0.0006
Onchocerca volvulus	4.1 G protein, putative homolog	0.0013	0.0006	0.0006
Trichomonas vaginalis	AGC family protein kinase	0.0017	0.0039	0.0035
Onchocerca volvulus		0.0203	0.1676	0.1738
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Trichomonas vaginalis	CAMK family protein kinase	0.0017	0.0039	0.0035
Brugia malayi	hypothetical protein	0.0013	0.0006	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0006	0.0006
Echinococcus granulosus	FERM central domain	0.0013	0.0006	0.0006
Echinococcus granulosus	CDC7 cell division cycle 7	0.1106	0.9641	0.9757
Loa Loa (eye worm)	CMGC/CDK/CDK9 protein kinase	0.0055	0.037	0.037
Echinococcus multilocularis	FERM domain containing protein 5	0.0013	0.0006	0.0006
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0213	0.1768	0.1768

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 863784