Detailed information for compound 898494

Basic information

Technical information
  • TDR Targets ID: 898494
  • Name: 4-bromo-N-(4-ethoxy-2-nitrophenyl)benzamide
  • MW: 365.179 | Formula: C15H13BrN2O4
  • H donors: 1 H acceptors: 3 LogP: 4.17 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(c(c1)[N+](=O)[O-])NC(=O)c1ccc(cc1)Br
  • InChi: 1S/C15H13BrN2O4/c1-2-22-12-7-8-13(14(9-12)18(20)21)17-15(19)10-3-5-11(16)6-4-10/h3-9H,2H2,1H3,(H,17,19)
  • InChiKey: QZNKRXJZIQMGCX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-bromo-N-(4-ethoxy-2-nitro-phenyl)benzamide
  • Oprea1_659897
  • ZINC04031836

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0188 0.0453
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0139 0.0457
Schistosoma mansoni DNA topoisomerase type I 0.0281 0.3036 0.7301
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0066 0.0066
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0066 0.0298
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.1534 0.2645
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0075
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0066 0.0298
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0162 0.0162
Brugia malayi nuclear hormone receptor 0.0031 0.0066 0.0113
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0126 0.0413
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0139 0.0457
Leishmania major DNA topoisomerase IB, large subunit 0.0281 0.3036 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0156 0.1545 0.3716
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0234 0.0561
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0076 0.0181
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0139 0.0457
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0066 0.0066
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0234 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0029 0.0071
Echinococcus granulosus lysine specific demethylase 5A 0.0097 0.0848 0.2039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0066 0.0113
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0066 0.0158
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0066 0.0066
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0188 0.1162
Brugia malayi Muscleblind-like protein 0.0159 0.1591 0.2742
Schistosoma mansoni single-minded 0.0052 0.031 0.0746
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0389 0.067
Schistosoma mansoni DNA topoisomerase type I 0.0281 0.3036 0.7301
Schistosoma mansoni hypothetical protein 0.0165 0.1654 0.3978
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0281 0.3036 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0075
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0066 0.0113
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0566 0.136
Loa Loa (eye worm) jmjC domain-containing protein 0.0097 0.0848 0.1462
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0464 0.1115
Brugia malayi PHD-finger family protein 0.0028 0.0029 0.0051
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0075
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0188 1
Onchocerca volvulus Huntingtin homolog 0.0131 0.1249 1
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0066 0.0158
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0076 0.0181
Brugia malayi hypoxia-induced factor 1 0.0161 0.1606 0.2768
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0234 0.0561
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0076 0.0181
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0076 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.047 0.1548
Plasmodium falciparum phd finger protein, putative 0.0028 0.0029 0.0071
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0234 0.0561
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0066 0.0113
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.047 0.113
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0066 0.0066
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0149 0.0149
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0076 0.0181
Brugia malayi PAS domain containing protein 0.0052 0.031 0.0534
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.031 0.0746
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0066 0.0113
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0139 0.0239
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.047 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0066 0.0113
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0066 0.0158
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0066 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0066 0.0113
Loa Loa (eye worm) hypothetical protein 0.0131 0.1249 0.2153
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0066 0.0066
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0076 0.0249
Entamoeba histolytica hypothetical protein 0.0073 0.0566 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0066 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0066 0.0113
Brugia malayi hypothetical protein 0.0174 0.1766 0.3045
Brugia malayi hypothetical protein 0.0131 0.1249 0.2153
Entamoeba histolytica hypothetical protein 0.0073 0.0566 1
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0076 0.013
Loa Loa (eye worm) hypothetical protein 0.0513 0.5801 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0029 0.0071
Brugia malayi MH2 domain containing protein 0.0243 0.2592 0.4468
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0066 0.0113
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0113
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0139 0.0334
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0464 0.9805
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0162 0.0389
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.1534 0.1534
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0464 0.1527
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0076 0.0249
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0464 0.1115
Loa Loa (eye worm) hypothetical protein 0.0065 0.047 0.081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0113
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0066 0.0158
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0066 0.0158
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0113
Trypanosoma brucei unspecified product 0.0038 0.0139 0.0457
Leishmania major DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Brugia malayi Bromodomain containing protein 0.0032 0.0075 0.0128
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0066 0.0158
Echinococcus granulosus single minded 2 0.0038 0.0149 0.0359
Leishmania major DNA polymerase eta, putative 0.0036 0.0126 0.0413
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0149 0.0257
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0066 0.0158
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0305 0.0525
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0566 0.136
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0066 0.0066
Echinococcus multilocularis peregrin 0.0032 0.0075 0.0074
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0464 0.0464
Leishmania major DNA topoisomerase type IB small subunit 0.0094 0.0814 0.2681
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0029 0.0029
Echinococcus multilocularis dna polymerase eta 0.0062 0.0434 0.0434
Loa Loa (eye worm) MH2 domain-containing protein 0.0243 0.2592 0.4468
Loa Loa (eye worm) hypothetical protein 0.0131 0.1249 0.2153
Giardia lamblia DINP protein human, muc B family 0.0038 0.0139 0.688
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0066 0.0158
Brugia malayi DNA topoisomerase I 0.0375 0.4159 0.7169
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0066 0.0158
Echinococcus multilocularis survival motor neuron protein 1 0.0252 0.2698 0.2698
Schistosoma mansoni hypothetical protein 0.0165 0.1654 0.3978
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0113
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0066 0.0158
Echinococcus multilocularis lysine specific demethylase 5A 0.0097 0.0848 0.0848
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0076 0.013
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0076 0.0249
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.0434 0.0748
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0066 0.0158
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0066 0.0113
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0066 0.0066
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.047 0.047
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0066 0.0113
Trypanosoma brucei DNA polymerase eta, putative 0.0062 0.0434 0.1429
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0066 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0234 1
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0139 0.0457
Echinococcus granulosus dna polymerase kappa 0.0038 0.0139 0.0334
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.047 0.113
Echinococcus granulosus geminin 0.0165 0.1654 0.3978
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0848 0.2039
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0464 0.9805
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0066 0.0158
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0066 0.0113
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0139 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0066 0.0113
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0066 0.0158
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0464 0.1115
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Brugia malayi steroid hormone receptor 0.0031 0.0066 0.0113
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0139 0.0239
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0029 0.0071
Echinococcus granulosus dna polymerase eta 0.0062 0.0434 0.1043
Leishmania major DNA polymerase eta, putative 0.0062 0.0434 0.1429
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0464 0.9836
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0281 0.3036 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0066 0.0113
Loa Loa (eye worm) hypothetical protein 0.0062 0.0434 0.0748
Brugia malayi jmjC domain containing protein 0.0156 0.1545 0.2664
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0149 0.032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.047 1
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0066 0.0066
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0139 0.1603
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0029 0.0051
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.1534 0.3689
Schistosoma mansoni DNA polymerase eta 0.0062 0.0434 0.1043
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0139 0.0334
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0464 0.1115
Onchocerca volvulus 0.0051 0.0305 0.2258
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0066 0.0158
Plasmodium falciparum topoisomerase I 0.0375 0.4159 1
Brugia malayi hypothetical protein 0.0252 0.2698 0.465
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0066 0.0158
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0066 0.0298
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0848 0.2039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0066 0.0113
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0234 0.0561
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0066 0.0158
Loa Loa (eye worm) hypothetical protein 0.0159 0.1591 0.2742
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0066 0.0113
Brugia malayi jmjC domain containing protein 0.0097 0.0848 0.1462
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.047 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0066 0.0113
Loa Loa (eye worm) DNA topoisomerase I 0.0375 0.4159 0.7169
Onchocerca volvulus 0.0038 0.0149 0.0984
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0066 0.0113
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0139 0.0139
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.0094 0.0814 0.2681
Entamoeba histolytica hypothetical protein 0.0073 0.0566 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0566 0.0566
Entamoeba histolytica hypothetical protein 0.0073 0.0566 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0076 0.0075
Onchocerca volvulus Huntingtin homolog 0.0131 0.1249 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0126 0.0302
Echinococcus granulosus survival motor neuron protein 1 0.0252 0.2698 0.6487
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0066 0.0113
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.0094 0.0814 0.2681
Loa Loa (eye worm) acetyltransferase 0.0155 0.1534 0.2645
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0066 0.0158
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0139 0.1603
Loa Loa (eye worm) transcription factor SMAD2 0.0243 0.2592 0.4468
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0156 0.1545 0.1545
Brugia malayi hypothetical protein 0.0073 0.0566 0.0975
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0113
Loa Loa (eye worm) hypoxia-induced factor 1 0.0161 0.1606 0.2768
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0076 0.0249
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0066 0.0066
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0372 0.0641
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0066 0.0113
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0051
Schistosoma mansoni survival motor neuron protein 0.0051 0.0305 0.0733
Loa Loa (eye worm) hypothetical protein 0.0159 0.1591 0.2742
Echinococcus multilocularis DNA topoisomerase 1 0.0375 0.4159 0.4159
Schistosoma mansoni hypothetical protein 0.0073 0.0566 0.136
Schistosoma mansoni hypothetical protein 0.0028 0.0029 0.0071
Toxoplasma gondii DNA topoisomerase I, putative 0.0375 0.4159 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0513 0.5801 1
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0066 0.0158
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0066 0.0113
Schistosoma mansoni hypothetical protein 0.0051 0.0305 0.0733
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0029 0.0071
Schistosoma mansoni DNA topoisomerase type I 0.0375 0.4159 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0139 0.0457
Loa Loa (eye worm) hypothetical protein 0.0252 0.2698 0.465
Brugia malayi isocitrate dehydrogenase 0.0032 0.0076 0.013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0464 0.9805
Echinococcus granulosus DNA topoisomerase 1 0.0375 0.4159 1
Schistosoma mansoni jumonji domain containing protein 0.0136 0.1318 0.3169
Echinococcus multilocularis muscleblind protein 1 0.0159 0.1591 0.1591
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0066 0.0113
Echinococcus granulosus muscleblind protein 0.0159 0.1591 0.3825
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0076 0.0181
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.1483 0.3565
Plasmodium vivax topoisomerase I, putative 0.0375 0.4159 1
Loa Loa (eye worm) hypothetical protein 0.0174 0.1766 0.3045
Echinococcus multilocularis muscleblind protein 0.0159 0.1591 0.1591
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0076 0.0249
Trypanosoma cruzi DNA polymerase eta, putative 0.0062 0.0434 0.1429
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.047 0.081
Echinococcus multilocularis geminin 0.0165 0.1654 0.1654
Echinococcus granulosus peregrin 0.0032 0.0075 0.0179
Brugia malayi nuclear receptor NHR-88 0.0031 0.0066 0.0113
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0029 0.0071
Schistosoma mansoni coup transcription factor 0.0031 0.0066 0.0158
Onchocerca volvulus 0.0031 0.0066 0.0298
Brugia malayi ecdysteroid receptor 0.0031 0.0066 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0066 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0066 0.0113
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0139 0.0139
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0076 0.0181
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0139 0.0457

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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