Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0785 | 0.2334 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0039 | 0.0044 |
Brugia malayi | RNA binding protein | 0.0128 | 0.0298 | 0.1279 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0042 | 0.0031 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0343 | 0.1469 |
Echinococcus multilocularis | snurportin 1 | 0.0312 | 0.0869 | 0.0869 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0297 | 0.0822 | 0.5 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0297 | 0.0822 | 0.5 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0049 | 0.0052 | 0.0052 |
Trypanosoma cruzi | inosine-5'-monophosphate dehydrogenase, putative | 0.0637 | 0.1874 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0108 | 0.0237 | 0.1179 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0515 | 0.1498 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0011 | 0.0011 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0101 | 0.0213 | 0.0465 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0312 | 0.0869 | 0.3723 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0298 | 0.1487 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0054 | 0.0069 | 0.0208 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0515 | 0.1498 | 0.6368 |
Trypanosoma cruzi | GMP reductase | 0.0637 | 0.1874 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Mycobacterium ulcerans | inosine 5-monophosphate dehydrogenase | 0.0627 | 0.1843 | 0.4228 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0052 | 0.0223 |
Trypanosoma cruzi | inosine-5'-monophosphate dehydrogenase, putative | 0.0637 | 0.1874 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0096 | 0.0198 | 0.0198 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0094 | 0.0192 | 0.0821 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0192 | 0.0495 | 0.2467 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0049 | 0.0052 | 0.0052 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0042 | 0.0031 | 0.0042 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.0365 | 0.1812 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0031 | 0.0133 |
Leishmania major | inosine-5-monophosphate dehydrogenase | 0.0637 | 0.1874 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0011 | 0.0055 |
Mycobacterium ulcerans | AcrR family transcriptional regulator | 0.1425 | 0.4317 | 1 |
Mycobacterium leprae | Probable transcriptional regulatory repressor protein (TetR-family) EthR | 0.1425 | 0.4317 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0785 | 0.2334 | 1 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0042 | 0.0031 | 0.0042 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0073 | 0.0313 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0031 | 0.0133 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.015 | 0.0365 | 0.1812 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0785 | 0.2334 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0042 | 0.0031 | 0.0133 |
Loa Loa (eye worm) | TAR-binding protein | 0.0128 | 0.0298 | 0.1279 |
Echinococcus multilocularis | geminin | 0.068 | 0.2007 | 0.2007 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0228 | 0.0975 |
Onchocerca volvulus | 0.0237 | 0.0636 | 0.4127 | |
Leishmania major | guanosine monophosphate reductase | 0.0637 | 0.1874 | 1 |
Mycobacterium ulcerans | TetR family transcriptional regulator | 0.1425 | 0.4317 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0515 | 0.1498 | 0.6368 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0049 | 0.0052 | 0.026 |
Echinococcus multilocularis | inosine 5' monophosphate dehydrogenase 2 | 0.0637 | 0.1874 | 0.1874 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0231 | 0.0991 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0515 | 0.1498 | 0.6368 |
Trypanosoma brucei | inosine-5'-monophosphate dehydrogenase | 0.0637 | 0.1874 | 1 |
Loa Loa (eye worm) | IMP dehydrogenase 1 | 0.0637 | 0.1874 | 0.8027 |
Mycobacterium ulcerans | transcriptional regulator | 0.1425 | 0.4317 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0106 | 0.0231 | 0.5 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0203 | 0.0531 | 0.2648 |
Brugia malayi | inosine-5'-monophosphate dehydrogenase | 0.0277 | 0.0759 | 0.3254 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0042 | 0.0031 | 0.0133 |
Echinococcus granulosus | inosine 5' monophosphate dehydrogenase 2 | 0.0637 | 0.1874 | 0.9337 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0042 | 0.0031 | 0.0133 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0042 | 0.0031 | 0.0042 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0101 | 0.0213 | 0.0465 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0052 | 0.026 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0042 | 0.0031 | 0.0133 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0158 | 0.0788 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0086 | 0.0168 | 0.0836 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0042 | 0.0031 | 0.0042 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0027 | 0.0027 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0049 | 0.0052 | 0.0144 |
Brugia malayi | AMP-binding enzyme family protein | 0.0142 | 0.0343 | 0.1469 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0213 | 0.0911 |
Brugia malayi | AMP-binding enzyme family protein | 0.0142 | 0.0343 | 0.1469 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 0.0639 | 0.0639 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0049 | 0.0052 | 0.0224 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.02 | 0.0522 | 0.2236 |
Brugia malayi | RNA, U transporter 1 | 0.0083 | 0.0159 | 0.0682 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0142 | 0.0343 | 0.0727 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0145 | 0.0351 | 0.0746 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0128 | 0.0298 | 0.1279 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0237 | 0.26 |
Trypanosoma brucei | GMP reductase | 0.0637 | 0.1874 | 1 |
Brugia malayi | GMP reductase | 0.0277 | 0.0759 | 0.3254 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0073 | 0.0073 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0316 | 0.0881 | 0.4611 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 0.0639 | 0.3183 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0073 | 0.0313 |
Echinococcus granulosus | tar DNA binding protein | 0.0128 | 0.0298 | 0.1487 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0192 | 0.0955 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0042 | 0.0031 | 0.0042 |
Brugia malayi | AMP-binding enzyme family protein | 0.0042 | 0.0031 | 0.0133 |
Mycobacterium ulcerans | inosine 5-monophosphate dehydrogenase | 0.0287 | 0.079 | 0.177 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0108 | 0.0237 | 0.0237 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0073 | 0.0364 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0142 | 0.0343 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.0522 | 0.2236 |
Brugia malayi | Pre-SET motif family protein | 0.0208 | 0.0547 | 0.2345 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0042 | 0.0031 | 0.0042 |
Onchocerca volvulus | Putative GMP reductase | 0.0277 | 0.0759 | 0.4967 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0108 | 0.0237 | 0.1179 |
Schistosoma mansoni | hypothetical protein | 0.068 | 0.2007 | 1 |
Brugia malayi | TAR-binding protein | 0.0128 | 0.0298 | 0.1279 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0086 | 0.0168 | 0.0836 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.02 | 0.0522 | 0.0522 |
Plasmodium vivax | inosine-5'-monophosphate dehydrogenase, putative | 0.0627 | 0.1843 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0142 | 0.0343 | 0.1691 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0192 | 0.0955 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0298 | 0.1487 |
Brugia malayi | AMP-binding enzyme family protein | 0.0042 | 0.0031 | 0.0133 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0543 | 0.1583 | 0.6741 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0042 | 0.0031 | 0.0155 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0237 | 0.26 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.02 | 0.0522 | 0.6208 |
Brugia malayi | inosine-5'-monophosphate dehydrogenase | 0.0277 | 0.0759 | 0.3254 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.0365 | 0.1812 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0785 | 0.2334 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0073 | 0.0364 |
Schistosoma mansoni | jumonji domain containing protein | 0.0076 | 0.0137 | 0.0682 |
Echinococcus granulosus | geminin | 0.068 | 0.2007 | 1 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0052 | 0.0224 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0316 | 0.0881 | 0.4611 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0094 | 0.0192 | 0.0821 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0049 | 0.0052 | 0.026 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0145 | 0.0351 | 0.0746 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0027 | 0.0137 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0298 | 0.1487 |
Trypanosoma cruzi | inosine-5'-monophosphate dehydrogenase, putative | 0.0637 | 0.1874 | 1 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0042 | 0.0031 | 0.0042 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0044 | 0.0039 | 0.0044 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0316 | 0.0881 | 0.4611 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0142 | 0.0343 | 0.0727 |
Echinococcus multilocularis | tar DNA binding protein | 0.0128 | 0.0298 | 0.0298 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.0192 | 0.0955 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0106 | 0.0231 | 0.0467 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0052 | 0.0224 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0515 | 0.1498 | 0.6368 |
Mycobacterium ulcerans | inosine 5'-monophosphate dehydrogenase | 0.0637 | 0.1874 | 0.4299 |
Mycobacterium tuberculosis | Transcriptional regulatory repressor protein (TetR-family) EthR | 0.1425 | 0.4317 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0231 | 0.0991 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0042 | 0.0031 | 0.0133 |
Brugia malayi | inosine-5'-monophosphate dehydrogenase family protein | 0.0637 | 0.1874 | 0.8027 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0011 | 0.0055 |
Onchocerca volvulus | 0.0049 | 0.0052 | 0.0144 | |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0052 | 0.0259 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0142 | 0.0343 | 0.0727 |
Brugia malayi | hypothetical protein | 0.0238 | 0.0639 | 0.2737 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0142 | 0.0343 | 0.0766 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0515 | 0.1498 | 0.6368 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0086 | 0.0168 | 0.0593 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0286 | 0.0788 | 0.3927 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0106 | 0.0231 | 0.1104 |
Onchocerca volvulus | 0.0142 | 0.0343 | 0.2125 | |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0039 | 0.0044 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0052 | 0.0259 |
Loa Loa (eye worm) | GMP reductase | 0.0277 | 0.0759 | 0.3254 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0142 | 0.0343 | 0.0727 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0049 | 0.0052 | 0.026 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0158 | 0.0788 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0142 | 0.0343 | 0.1691 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0073 | 0.0313 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0101 | 0.0213 | 0.0465 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0237 | 0.26 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0142 | 0.0343 | 0.3943 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0142 | 0.0343 | 0.0727 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0052 | 0.0224 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0166 | 0.0417 | 0.0939 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0168 | 0.0719 |
Trichomonas vaginalis | set domain proteins, putative | 0.0237 | 0.0636 | 0.2628 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.0213 | 0.0911 |
Echinococcus granulosus | snurportin 1 | 0.0312 | 0.0869 | 0.433 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0042 | 0.0031 | 0.0155 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0208 | 0.0547 | 0.2345 |
Wolbachia endosymbiont of Brugia malayi | IMP dehydrogenase | 0.0637 | 0.1874 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0011 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0343 | 0.1469 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0515 | 0.1498 | 0.6368 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0785 | 0.2334 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0044 | 0.0039 | 0.0044 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0114 | 0.0489 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0298 | 0.1487 |
Trypanosoma cruzi | GMP reductase | 0.0637 | 0.1874 | 1 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0086 | 0.0168 | 0.0719 |
Mycobacterium leprae | Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) | 0.0637 | 0.1874 | 0.4299 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0231 | 0.0991 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0231 | 0.0991 |
Toxoplasma gondii | hypothetical protein | 0.0051 | 0.006 | 0.0154 |
Mycobacterium leprae | Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena | 0.035 | 0.0985 | 0.2227 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.02 | 0.0522 | 0.26 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0158 | 0.0788 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0073 | 0.0364 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.0192 | 0.0955 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0142 | 0.0343 | 0.0727 |
Brugia malayi | jmjC domain containing protein | 0.0096 | 0.0198 | 0.0847 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0785 | 0.2334 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0142 | 0.0343 | 0.0766 |
Schistosoma mansoni | patched 1 | 0.0086 | 0.0168 | 0.0836 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0543 | 0.1583 | 0.6741 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0101 | 0.0213 | 0.0465 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0192 | 0.0955 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0142 | 0.0343 | 0.0727 |
Brugia malayi | hypothetical protein | 0.0108 | 0.0237 | 0.1014 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0042 | 0.0031 | 0.0042 |
Brugia malayi | AMP-binding enzyme family protein | 0.0042 | 0.0031 | 0.0133 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0785 | 0.2334 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0142 | 0.0343 | 0.1691 |
Plasmodium falciparum | inosine-5'-monophosphate dehydrogenase | 0.0627 | 0.1843 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0343 | 0.1469 |
Brugia malayi | AMP-binding enzyme family protein | 0.0142 | 0.0343 | 0.1469 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.0237 | 0.1179 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0106 | 0.0231 | 0.0507 |
Brugia malayi | CHE-14 protein | 0.0086 | 0.0168 | 0.0719 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0142 | 0.0343 | 0.3943 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0042 | 0.0031 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.0312 | 0.0869 | 0.433 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.0192 | 0.0192 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.0192 | 0.0192 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0114 | 0.0569 |
Mycobacterium tuberculosis | Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase | 0.0637 | 0.1874 | 0.4323 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0142 | 0.0343 | 0.0727 |
Echinococcus granulosus | expressed conserved protein | 0.0188 | 0.0484 | 0.2413 |
Toxoplasma gondii | IMP dehydrogenas | 0.0637 | 0.1874 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0192 | 0.0495 | 0.0495 |
Schistosoma mansoni | hypothetical protein | 0.068 | 0.2007 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0785 | 0.2334 | 1 |
Echinococcus multilocularis | protein patched | 0.0086 | 0.0168 | 0.0168 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0096 | 0.0198 | 0.0986 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0042 | 0.0031 | 0.0031 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.0822 | 0.3432 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0316 | 0.0881 | 0.4611 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.0817 | 0.4073 |
Loa Loa (eye worm) | oxidoreductase | 0.0042 | 0.0031 | 0.0133 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.0213 | 0.0911 |
Mycobacterium ulcerans | hypothetical protein | 0.0142 | 0.0343 | 0.0727 |
Mycobacterium tuberculosis | Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase | 0.035 | 0.0985 | 0.2259 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0114 | 0.0489 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.0213 | 0.0911 |
Schistosoma mansoni | inosine-5-monophosphate dehydrogenase | 0.0637 | 0.1874 | 0.9337 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0142 | 0.0343 | 0.3943 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0106 | 0.0231 | 0.1104 |
Echinococcus multilocularis | protein dispatched 1 | 0.0098 | 0.0205 | 0.0205 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0011 | 0.0047 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.0298 | 0.1487 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0145 | 0.0351 | 0.0785 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0286 | 0.0788 | 0.0788 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0042 | 0.0031 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0057 | 0.0243 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0086 | 0.0168 | 0.0168 |
Mycobacterium leprae | PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) | 0.0287 | 0.079 | 0.177 |
Loa Loa (eye worm) | RNA binding protein | 0.0128 | 0.0298 | 0.1279 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0231 | 0.0991 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0011 | 0.0055 |
Mycobacterium ulcerans | hypothetical protein | 0.0166 | 0.0417 | 0.0901 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0052 | 0.026 |
Echinococcus multilocularis | expressed conserved protein | 0.0188 | 0.0484 | 0.0484 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0128 | 0.0298 | 0.1279 |
Onchocerca volvulus | 0.005 | 0.0055 | 0.0164 | |
Onchocerca volvulus | 0.0049 | 0.0052 | 0.0142 | |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.0639 | 0.2737 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0237 | 0.26 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0088 | 0.0378 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0158 | 0.0788 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0515 | 0.1498 | 0.6368 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.