TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 415.42 | Formula: C23H18FN5O2
H donors: 3 H acceptors: 4 LogP: 2.99 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: Fc1ccc(cc1)NC(=O)c1[nH]cnc1C(=O)NCc1ccccc1c1ccncc1
InChi: 1S/C23H18FN5O2/c24-17-5-7-18(8-6-17)29-23(31)21-20(27-14-28-21)22(30)26-13-16-3-1-2-4-19(16)15-9-11-25-12-10-15/h1-12,14H,13H2,(H,26,30)(H,27,28)(H,29,31)
InChiKey: GWLMKRYEIZPZKL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Loa Loa (eye worm)	hypothetical protein	0.0133	0.1957	0.1953
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Onchocerca volvulus	Slit protein homolog	0.0028	0.016	0.0601
Loa Loa (eye worm)	hypothetical protein	0.0126	0.1836	0.1832
Echinococcus granulosus	protein jagged 1	0.0028	0.016	0.0258
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0054	0.0606	0.3118
Loa Loa (eye worm)	hypothetical protein	0.0606	1	1
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0033	0.0248	0.0243
Toxoplasma gondii	hypothetical protein	0.002	0.0034	0.0057
Loa Loa (eye worm)	large conductance calcium-activated potassium channel alpha subunit ai	0.0042	0.0407	0.0402
Brugia malayi	PAS domain containing protein	0.0067	0.0824	0.0819
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0033	0.0248	0.0243
Echinococcus multilocularis	neural cadherin	0.0028	0.016	0.0258
Schistosoma mansoni	slit	0.0028	0.016	0.052
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Echinococcus multilocularis	potassium large conductance calcium activated	0.0045	0.0461	0.0761
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Schistosoma mansoni	peroxidasin	0.0055	0.0627	0.2089
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	0.0133	0.1945	1
Brugia malayi	Animal haem peroxidase family protein	0.0055	0.0627	0.0622
Brugia malayi	Calcium binding EGF domain containing protein	0.0028	0.016	0.0155
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0033	0.0248	0.0243
Loa Loa (eye worm)	Notch2	0.0028	0.016	0.0155
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0033	0.0248	0.0406
Mycobacterium ulcerans	heat shock protein 90	0.0053	0.0598	0.6576
Trypanosoma cruzi	heat shock protein 90, putative	0.0067	0.0831	0.4272
Onchocerca volvulus	Protein ultraspiracle homolog	0.0033	0.0248	0.1022
Brugia malayi	Kringle domain containing protein	0.0063	0.0756	0.0751
Loa Loa (eye worm)	PAN domain-containing protein	0.002	0.0034	0.0029
Schistosoma mansoni	notch	0.0028	0.016	0.052
Loa Loa (eye worm)	hypothetical protein	0.0133	0.1957	0.1953
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0097	0.0091
Onchocerca volvulus		0.0028	0.016	0.0601
Echinococcus granulosus	glycoprotein Antigen 5	0.0024	0.0097	0.0152
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0019	0.0005	0.0027
Echinococcus multilocularis	nuclear factor of activated T cells 5	0.0081	0.1064	0.1766
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0033	0.0248	0.0243
Echinococcus granulosus	neural cadherin	0.0028	0.016	0.0258
Toxoplasma gondii	PAN domain-containing protein	0.0316	0.5058	1
Brugia malayi	Animal haem peroxidase family protein	0.0055	0.0627	0.0622
Schistosoma mansoni	hypothetical protein	0.0024	0.0097	0.0307
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0033	0.0248	0.0817
Mycobacterium tuberculosis	Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G)	0.0053	0.0598	0.6576
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Schistosoma mansoni	calcium-activated potassium channel	0.0042	0.0407	0.1351
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Onchocerca volvulus	Peroxidasin homolog	0.0055	0.0627	0.2827
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Echinococcus granulosus	mitogen activated protein kinase	0.0054	0.0606	0.1003
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0097	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Schistosoma mansoni	Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)]	0.0028	0.016	0.052
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0033	0.0248	0.1022
Echinococcus granulosus	aryl hydrocarbon receptor	0.0144	0.2141	0.3564
Trypanosoma brucei	heat shock protein 90, putative	0.0067	0.0831	0.4257
Onchocerca volvulus		0.0024	0.0097	0.0298
Onchocerca volvulus	Peroxidase homolog	0.0055	0.0627	0.2827
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Schistosoma mansoni	laminin gamma-3 chain	0.0028	0.016	0.052
Mycobacterium ulcerans	chitinase/cellulase	0.0072	0.0907	1
Echinococcus granulosus	single minded 2	0.0049	0.0529	0.0874
Plasmodium falciparum	heat shock protein 90, putative	0.0028	0.0157	0.0775
Toxoplasma gondii	Hsp90 domain-containing protein	0.0028	0.0157	0.0299
Onchocerca volvulus		0.0024	0.0097	0.0298
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0033	0.0248	0.0406
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0033	0.0248	0.0243
Onchocerca volvulus		0.005	0.0539	0.2406
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0033	0.0248	0.0406
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Brugia malayi	Hepatocellular carcinoma-associated antigen 59 family protein	0.0133	0.1957	0.1953
Echinococcus multilocularis	neurogenic locus notch protein	0.0028	0.016	0.0258
Brugia malayi	Trypsin family protein	0.0024	0.0097	0.0091
Echinococcus granulosus	fibropellin Ia	0.0028	0.016	0.0258
Trichomonas vaginalis	CMGC family protein kinase	0.0054	0.0606	0.728
Brugia malayi	endochitinase	0.0094	0.129	0.1285
Brugia malayi	photoreceptor-specific nuclear receptor	0.0033	0.0248	0.0243
Trypanosoma cruzi	heat shock protein 90, putative	0.0053	0.0598	0.3076
Echinococcus granulosus	jun protein	0.0088	0.1188	0.1973
Loa Loa (eye worm)	microfilarial chitinase	0.0082	0.1079	0.1075
Entamoeba histolytica	heat shock protein 90, putative	0.0067	0.0831	0.7423
Brugia malayi	Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog	0.003	0.0202	0.0197
Trypanosoma brucei	heat shock protein 84, putative	0.0028	0.0157	0.078
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0019	0.0005	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Onchocerca volvulus		0.0028	0.016	0.0601
Trichomonas vaginalis	heat shock protein, putative	0.0053	0.0598	0.7182
Onchocerca volvulus	Dual oxidase homolog	0.0055	0.0627	0.2827
Schistosoma mansoni	cellular tumor antigen P53	0.0054	0.0612	0.2038
Brugia malayi	Chymotrypsin-like protease CTRL-1 precursor	0.0024	0.0097	0.0091
Onchocerca volvulus		0.0028	0.016	0.0601
Plasmodium vivax	endoplasmin, putative	0.0067	0.0831	0.423
Plasmodium falciparum	heat shock protein 90, putative	0.0028	0.0157	0.0775
Brugia malayi	Trypsin family protein	0.0024	0.0097	0.0091
Giardia lamblia	Kinase, CMGC MAPK	0.0054	0.0606	0.728
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0307
Loa Loa (eye worm)	hypothetical protein	0.002	0.0034	0.0029
Brugia malayi	Cadherin domain containing protein	0.0028	0.016	0.0155
Schistosoma mansoni	RAR-like nuclear receptor	0.0033	0.0248	0.0817
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.0054	0.0606	0.3118
Toxoplasma gondii	PAN domain-containing protein	0.002	0.0034	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0097	0.0091
Toxoplasma gondii	PAN domain-containing protein	0.002	0.0034	0.0057
Echinococcus granulosus	mitogen activated protein kinase 14	0.0133	0.1945	0.3236
Brugia malayi	Hsp90 protein	0.0028	0.0157	0.0151
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0141	0.2089	0.3477
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Schistosoma mansoni	calcium-activated potassium channel	0.0045	0.0461	0.1533
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Echinococcus granulosus	enteropeptidase	0.0024	0.0097	0.0152
Schistosoma mansoni	hypothetical protein	0.0028	0.016	0.052
Echinococcus multilocularis	transfer RNA-Lys	0.0049	0.0529	0.0874
Entamoeba histolytica	hypothetical protein	0.0077	0.1003	0.8967
Loa Loa (eye worm)	MaxiK calcium-activated potassium channel	0.003	0.0202	0.0197
Brugia malayi	EGF-like domain containing protein	0.0028	0.016	0.0155
Loa Loa (eye worm)	hypothetical protein	0.002	0.0034	0.0029
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Brugia malayi	hypothetical protein	0.0077	0.1003	0.0998
Onchocerca volvulus	Bile acid receptor homolog	0.0033	0.0248	0.1022
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0033	0.0248	0.0406
Echinococcus multilocularis	calcium activated potassium channel variant	0.0042	0.0407	0.0671
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Mycobacterium leprae	PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G)	0.0053	0.0598	0.5
Plasmodium falciparum	heat shock protein 90	0.0067	0.0831	0.423
Brugia malayi	notch-like transmembrane receptor	0.0028	0.016	0.0155
Brugia malayi	steroid hormone receptor	0.0033	0.0248	0.0243
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Brugia malayi	nuclear receptor NHR-88	0.0033	0.0248	0.0243
Loa Loa (eye worm)	cuticular endochitinase	0.0084	0.1117	0.1113
Echinococcus multilocularis	heat shock protein	0.0067	0.0831	0.1378
Brugia malayi	Calcium binding EGF domain containing protein	0.0028	0.016	0.0155
Toxoplasma gondii	PAN domain-containing protein	0.0316	0.5058	1
Brugia malayi	hypothetical protein	0.0069	0.0866	0.0861
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Leishmania major	mitogen-activated protein kinase 3, putative,map kinase 3, putative	0.0133	0.1945	1
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0612	0.0607
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0033	0.0248	0.0243
Echinococcus granulosus	calcium activated potassium channel variant	0.0042	0.0407	0.0671
Echinococcus granulosus	heat shock protein	0.0067	0.0831	0.1378
Loa Loa (eye worm)	endoplasmin	0.0067	0.0831	0.0826
Echinococcus multilocularis	FTZ F1 alpha	0.0033	0.0248	0.0406
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Brugia malayi	Peroxidasin	0.0055	0.0627	0.0622
Brugia malayi	Trypsin family protein	0.0024	0.0097	0.0091
Toxoplasma gondii	EGF family domain-containing protein	0.0028	0.016	0.0306
Brugia malayi	EGF-like domain containing protein	0.0028	0.016	0.0155
Brugia malayi	aryl hydrocarbon receptor AHR-1	0.0126	0.1836	0.1832
Echinococcus multilocularis	neurogenic locus notch protein	0.0028	0.016	0.0258
Trichomonas vaginalis	heat shock protein, putative	0.0067	0.0831	1
Brugia malayi	bHLH-PAS transcription factor	0.0049	0.0529	0.0524
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Trichomonas vaginalis	heat shock protein, putative	0.0053	0.0598	0.7182
Onchocerca volvulus	Putative endochitinase	0.0094	0.129	0.5987
Brugia malayi	hypothetical protein	0.0055	0.0627	0.0622
Trypanosoma cruzi	heat shock protein 85, putative	0.0067	0.0831	0.4272
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Toxoplasma gondii	PAN/Apple domain-containing protein	0.002	0.0034	0.0057
Loa Loa (eye worm)	animal heme peroxidase	0.0055	0.0627	0.0622
Toxoplasma gondii	hypothetical protein	0.0133	0.1957	0.3863
Toxoplasma gondii	PAN domain-containing protein	0.002	0.0034	0.0057
Plasmodium falciparum	cysteine repeat modular protein 1	0.0063	0.0756	0.3847
Onchocerca volvulus	Heat shock protein 75 kDa, mitochondrial homolog	0.0028	0.0157	0.0584
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0053	0.0598	0.7182
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Onchocerca volvulus		0.0063	0.0756	0.3443
Brugia malayi	hypothetical protein	0.0024	0.0097	0.0091
Loa Loa (eye worm)	hypothetical protein	0.002	0.0034	0.0029
Brugia malayi	MAP kinase sur-1	0.0054	0.0606	0.0601
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Onchocerca volvulus		0.0133	0.1957	0.9169
Brugia malayi	EGF-like domain containing protein	0.0028	0.016	0.0155
Onchocerca volvulus	Putative endochitinase	0.0094	0.129	0.5987
Echinococcus granulosus	Hepatocellular carcinoma associated antigen 59	0.0133	0.1957	0.3257
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Schistosoma mansoni	hypothetical protein	0.0072	0.0907	0.3029
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Mycobacterium ulcerans	chitinase/cellulase	0.0072	0.0907	1
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0033	0.0248	0.0406
Toxoplasma gondii	microneme protein MIC17A	0.002	0.0034	0.0057
Leishmania major	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	0.0053	0.0598	0.3076
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0033	0.0248	0.0243
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0307
Brugia malayi	GCC2 and GCC3 family protein	0.0028	0.016	0.0155
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0033	0.0248	0.0243
Mycobacterium tuberculosis	Possible chitinase	0.0072	0.0907	1
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0033	0.0248	0.0243
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0033	0.0248	0.0817
Plasmodium vivax	heat shock protein, putative	0.0028	0.0157	0.0775
Brugia malayi	Delta serrate ligand family protein	0.0028	0.016	0.0155
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Echinococcus multilocularis	jun protein	0.0088	0.1188	0.1973
Schistosoma mansoni	cell polarity protein	0.0028	0.016	0.052
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0097	0.0091
Brugia malayi	EGF-like domain containing protein	0.0028	0.016	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Schistosoma mansoni	retinoic acid receptor RXR	0.0141	0.2089	0.7002
Schistosoma mansoni	transcription factor LCR-F1	0.0077	0.1003	0.3351
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0756	0.0751
Toxoplasma gondii	heat shock protein HSP90	0.0067	0.0831	0.1634
Onchocerca volvulus		0.0024	0.0097	0.0298
Echinococcus multilocularis	protein jagged 1	0.0028	0.016	0.0258
Echinococcus multilocularis	endoplasmin	0.0053	0.0598	0.0989
Echinococcus multilocularis	Peptidase S1 S6, chymotrypsin Hap	0.0024	0.0097	0.0152
Wolbachia endosymbiont of Brugia malayi	heat shock protein 90	0.0053	0.0598	1
Brugia malayi	Muscle positioning protein 4	0.0028	0.016	0.0155
Echinococcus multilocularis	mitogen activated protein kinase	0.0054	0.0606	0.1003
Giardia lamblia	High cysteine protein	0.0028	0.016	0.1875
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0033	0.0248	0.0817
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Leishmania major	heat shock protein, putative	0.0028	0.0157	0.0805
Echinococcus multilocularis	neurogenic locus protein delta	0.0028	0.016	0.0258
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0024	0.0097	0.0307
Echinococcus multilocularis	aryl hydrocarbon receptor	0.0144	0.2141	0.3564
Loa Loa (eye worm)	animal heme peroxidase	0.0055	0.0627	0.0622
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0033	0.0248	0.0817
Schistosoma mansoni	notch	0.0028	0.016	0.052
Loa Loa (eye worm)	hypothetical protein	0.002	0.0034	0.0029
Echinococcus granulosus	ecdysone induced protein 78C	0.0033	0.0248	0.0406
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Loa Loa (eye worm)	hypothetical protein	0.002	0.0034	0.0029
Echinococcus multilocularis	Hepatocellular carcinoma associated antigen 59	0.0133	0.1957	0.3257
Onchocerca volvulus		0.0033	0.0248	0.1022
Echinococcus granulosus	Peptidase S1 S6 chymotrypsin Hap	0.0024	0.0097	0.0152
Echinococcus granulosus	transmembrane protease serine 3	0.0024	0.0097	0.0152
Echinococcus granulosus	FTZ F1 alpha	0.0033	0.0248	0.0406
Echinococcus multilocularis	neurogenic locus notch protein 4	0.0028	0.016	0.0258
Echinococcus granulosus	subfamily S1A unassigned peptidase S01 family	0.0024	0.0097	0.0152
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Echinococcus multilocularis	heat shock protein 90	0.0053	0.0598	0.0989
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Onchocerca volvulus		0.0028	0.016	0.0601
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.0054	0.0606	0.3118
Echinococcus granulosus	neurogenic locus notch protein	0.0028	0.016	0.0258
Echinococcus multilocularis	mitogen activated protein kinase 11	0.0133	0.1945	0.3236
Loa Loa (eye worm)	PAN domain-containing protein	0.002	0.0034	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0097	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0086	0.1146	0.1142
Echinococcus granulosus	tissue type plasminogen activator	0.0063	0.0756	0.1253
Echinococcus multilocularis	neurogenic locus protein delta	0.0028	0.016	0.0258
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1846	0.1842
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription factor	0.0088	0.1188	0.1973
Schistosoma mansoni	hypothetical protein	0.0028	0.016	0.052
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0097	0.0091
Trichomonas vaginalis	endoplasmin, putative	0.0041	0.0389	0.465
Chlamydia trachomatis	two component regulatory system sensor histidine kinase	0.0031	0.0216	0.5
Schistosoma mansoni	jun-related protein	0.0072	0.0907	0.3029
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0067	0.0831	1
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Mycobacterium ulcerans	hypothetical protein	0.0024	0.0097	0.1012
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Entamoeba histolytica	90 kDa heat shock protein, putative	0.0028	0.0157	0.136
Onchocerca volvulus		0.0024	0.0097	0.0298
Giardia lamblia	Grp94/Hsp90	0.0053	0.0598	0.7182
Leishmania major	chitinase	0.0084	0.1117	0.5746
Echinococcus multilocularis	protein jagged 1	0.0028	0.016	0.0258
Loa Loa (eye worm)	hypothetical protein	0.002	0.0034	0.0029
Echinococcus granulosus	neurogenic locus notch protein	0.0028	0.016	0.0258
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0033	0.0248	0.0406
Brugia malayi	endochitinase	0.0084	0.1117	0.1113
Toxoplasma gondii	microneme protein, putative	0.002	0.0034	0.0057
Loa Loa (eye worm)	chitinase I	0.0084	0.1117	0.1113
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Toxoplasma gondii	kringle domain-containing protein	0.0063	0.0756	0.1486
Entamoeba histolytica	hypothetical protein	0.0077	0.1003	0.8967
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Echinococcus multilocularis	mitogen activated protein kinase 14	0.0133	0.1945	0.3236
Loa Loa (eye worm)	PAN domain-containing protein	0.002	0.0034	0.0029
Schistosoma mansoni	hypothetical protein	0.0063	0.0756	0.2523
Echinococcus granulosus	endoplasmin	0.0053	0.0598	0.0989
Loa Loa (eye worm)	steroid hormone receptor	0.0033	0.0248	0.0243
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0054	0.0606	0.3118
Toxoplasma gondii	heat shock protein 90, putative	0.0067	0.0831	0.1634
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Brugia malayi	EGF-like domain containing protein	0.0028	0.016	0.0155
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	0.0133	0.1945	1
Echinococcus multilocularis	tissue type plasminogen activator	0.0063	0.0756	0.1253
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Trichomonas vaginalis	CMGC family protein kinase	0.0054	0.0606	0.728
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0033	0.0248	0.0243
Brugia malayi	bZIP transcription factor family protein	0.0088	0.1188	0.1183
Echinococcus granulosus	heat shock protein 75 kDa mitochondrial	0.0028	0.0157	0.0252
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0033	0.0248	0.0406
Onchocerca volvulus	Putative endochitinase	0.0094	0.129	0.5987
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0033	0.0248	0.0406
Echinococcus multilocularis	mitogen activated protein kinase 3	0.0054	0.0606	0.1003
Echinococcus multilocularis	heat shock protein 90	0.0067	0.0831	0.1378
Brugia malayi	Transmembrane cell adhesion receptor mua-3 precursor, putative	0.0028	0.016	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Loa Loa (eye worm)	TK/ROR protein kinase	0.0063	0.0756	0.0751
Onchocerca volvulus		0.0069	0.0866	0.3965
Onchocerca volvulus		0.0055	0.0627	0.2827
Echinococcus granulosus	nuclear factor of activated T cells 5	0.0081	0.1064	0.1766
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0033	0.0248	0.0243
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Echinococcus multilocularis	mitogen activated protein kinase 11	0.0133	0.1945	0.3236
Loa Loa (eye worm)	animal heme peroxidase	0.0055	0.0627	0.0622
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0307
Schistosoma mansoni	septate junction protein	0.0028	0.016	0.052
Echinococcus multilocularis	fat cadherin tumor suppressor	0.0028	0.016	0.0258
Echinococcus multilocularis	heat shock protein 75 kDa, mitochondrial	0.0028	0.0157	0.0252
Echinococcus granulosus	tumor protein p63	0.0371	0.5999	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0033	0.0248	0.0243
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Entamoeba histolytica	chitinase, putative	0.0084	0.1117	1
Trypanosoma cruzi	heat shock protein 90, putative	0.004	0.0363	0.1865
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0033	0.0248	0.0406
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0033	0.0248	0.0243
Onchocerca volvulus	Putative cubilin	0.0028	0.016	0.0601
Echinococcus granulosus	heat shock protein 90	0.0067	0.0831	0.1378
Schistosoma mansoni	heat shock protein	0.0028	0.0157	0.0508
Echinococcus multilocularis	notch	0.0028	0.016	0.0258
Trichomonas vaginalis	heat shock protein, putative	0.0028	0.0157	0.1832
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Onchocerca volvulus		0.0024	0.0097	0.0298
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0307
Loa Loa (eye worm)	trypsin family protein	0.0024	0.0097	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Brugia malayi	EGF-like domain containing protein	0.0028	0.016	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Brugia malayi	Protein kinase domain containing protein	0.0063	0.0756	0.0751
Schistosoma mansoni	heat shock protein	0.0067	0.0831	0.2774
Treponema pallidum	heat shock protein 90	0.0053	0.0598	1
Trypanosoma cruzi	heat shock protein 85, putative	0.0067	0.0831	0.4272
Trichomonas vaginalis	heat shock protein, putative	0.0041	0.0389	0.465
Trypanosoma cruzi	heat shock protein 85, putative	0.0067	0.0831	0.4272
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Echinococcus multilocularis	peroxidasin	0.0055	0.0627	0.1037
Brugia malayi	P38 map kinase family protein 2	0.0133	0.1945	0.1941
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Schistosoma mansoni	hypothetical protein	0.0028	0.016	0.052
Schistosoma mansoni	thyroid hormone receptor	0.0033	0.0248	0.0817
Schistosoma mansoni	cercarial elastase (S01 family)	0.0024	0.0097	0.0307
Schistosoma mansoni	thyroid hormone receptor	0.0033	0.0248	0.0817
Onchocerca volvulus		0.0144	0.2131	1
Echinococcus multilocularis	glycoprotein Antigen 5	0.0024	0.0097	0.0152
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Toxoplasma gondii	hypothetical protein	0.002	0.0034	0.0057
Brugia malayi	heat shock protein 90	0.0067	0.0831	0.0826
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0907	0.0902
Brugia malayi	ecdysteroid receptor	0.0033	0.0248	0.0243
Entamoeba histolytica	hypothetical protein	0.0077	0.1003	0.8967
Schistosoma mansoni	nuclear hormone receptor	0.0033	0.0248	0.0817
Schistosoma mansoni	heat shock protein	0.0067	0.0831	0.2774
Toxoplasma gondii	microneme protein MIC4	0.002	0.0034	0.0057
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.0054	0.0606	0.3099
Echinococcus multilocularis	mitogen activated protein kinase 14	0.0133	0.1945	0.3236
Onchocerca volvulus		0.0133	0.1957	0.9169
Trypanosoma cruzi	heat shock protein 85, putative	0.0053	0.0598	0.3076
Echinococcus multilocularis	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0152
Schistosoma mansoni	hypothetical protein	0.0024	0.0097	0.0307
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Plasmodium falciparum	conserved protein, unknown function	0.0133	0.1957	1
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0097	0.0091
Toxoplasma gondii	PAN domain-containing protein	0.002	0.0034	0.0057
Leishmania major	hypothetical protein, conserved	0.0063	0.0756	0.3888
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Brugia malayi	EGF-like domain containing protein	0.0028	0.016	0.0155
Onchocerca volvulus		0.0055	0.0627	0.2827
Trypanosoma brucei	mitogen-activated protein kinase 3, putative	0.0133	0.1945	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0033	0.0248	0.0243
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.0054	0.0606	0.1189
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0077	0.1003	0.1664
Toxoplasma gondii	1,3(4)-beta-glucanase	0.002	0.0034	0.0057
Schistosoma mansoni	hypothetical protein	0.0028	0.016	0.052
Mycobacterium ulcerans	putative regulatory protein	0.0049	0.0529	0.5807
Echinococcus granulosus	protein jagged 2	0.0028	0.016	0.0258
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.0054	0.0606	0.0601
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0307
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.0054	0.0606	0.3118
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0033	0.0248	0.0406
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0248	0.0243
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0033	0.0248	0.0406
Onchocerca volvulus	Putative endochitinase	0.0084	0.1117	0.5165
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0033	0.0248	0.0243
Trypanosoma cruzi	heat shock protein, putative	0.0028	0.0157	0.0805
Schistosoma mansoni	single-minded	0.0067	0.0824	0.2751
Schistosoma mansoni	notch	0.0028	0.016	0.052
Loa Loa (eye worm)	PAN domain-containing protein	0.002	0.0034	0.0029
Brugia malayi	Animal haem peroxidase family protein	0.0055	0.0627	0.0622
Loa Loa (eye worm)	hypothetical protein	0.002	0.0034	0.0029
Loa Loa (eye worm)	notch protein	0.0028	0.016	0.0155
Brugia malayi	Trypsin family protein	0.0024	0.0097	0.0091
Echinococcus multilocularis	calcium activated potassium channel	0.0046	0.0478	0.0789
Echinococcus granulosus	mitogen activated protein kinase 11	0.0133	0.1945	0.3236
Brugia malayi	Endochitinase	0.0094	0.129	0.1285
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Trypanosoma brucei	Heat shock protein 83, putative	0.0067	0.0831	0.4257
Echinococcus granulosus	potassium large conductance calcium activated	0.0045	0.0461	0.0761
Echinococcus granulosus	mitogen activated protein kinase 3	0.0054	0.0606	0.1003
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0033	0.0248	0.0243
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0307
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0033	0.0248	0.0817
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Schistosoma mansoni	endoplasmin	0.0067	0.0831	0.2774
Schistosoma mansoni	notch	0.0028	0.016	0.052
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.0054	0.0606	0.3118
Echinococcus granulosus	Basic leucine zipper bZIP transcription factor	0.0088	0.1188	0.1973
Trypanosoma brucei	heat shock protein 90, putative	0.0067	0.0831	0.4257
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Echinococcus granulosus	slit 2 protein	0.0028	0.016	0.0258
Schistosoma mansoni	hypothetical protein	0.0028	0.016	0.052
Loa Loa (eye worm)	blistered cuticle protein 3	0.0055	0.0627	0.0622
Trypanosoma brucei	protein kinase, putative	0.0054	0.0606	0.3099
Schistosoma mansoni	aryl hydrocarbon receptor	0.0194	0.2982	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0063	0.0756	0.3888
Onchocerca volvulus	Putative endochitinase	0.0084	0.1117	0.5165
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Plasmodium vivax	heat shock protein 86, putative	0.0067	0.0831	0.423
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Brugia malayi	Trypsin-like protease protein 5	0.0024	0.0097	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0033	0.0248	0.0406
Schistosoma mansoni	coup transcription factor	0.0033	0.0248	0.0817
Onchocerca volvulus		0.0054	0.0612	0.2756
Schistosoma mansoni	endoplasmin	0.0067	0.0831	0.2774
Brugia malayi	Cadherin domain containing protein	0.0028	0.016	0.0155
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0019	0.0005	0.0027
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0033	0.0248	0.0243
Entamoeba histolytica	hypothetical protein	0.0077	0.1003	0.8967
Brugia malayi	Calcium binding EGF domain containing protein	0.0028	0.016	0.0155
Schistosoma mansoni	notch	0.0028	0.0162	0.0528
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0124	0.1794	0.2984
Echinococcus granulosus	protein jagged 1	0.0028	0.016	0.0258
Onchocerca volvulus		0.0028	0.016	0.0601
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Echinococcus granulosus	neurogenic locus protein delta	0.0028	0.016	0.0258
Echinococcus granulosus	Mastin	0.0024	0.0097	0.0152
Toxoplasma gondii	microneme protein MIC17C	0.002	0.0034	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0033	0.0248	0.0243
Echinococcus multilocularis	tumor protein p63	0.0371	0.5999	1
Echinococcus multilocularis	ecdysone induced protein 78C	0.0033	0.0248	0.0406
Echinococcus granulosus	peroxidasin	0.0055	0.0627	0.1037
Schistosoma mansoni	hypothetical protein	0.0028	0.016	0.052
Brugia malayi	Animal haem peroxidase family protein	0.0055	0.0627	0.0622
Toxoplasma gondii	microneme protein MIC17B	0.002	0.0034	0.0057
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0077	0.1003	0.1664
Onchocerca volvulus	Peroxidase homolog	0.0055	0.0627	0.2827
Echinococcus granulosus	calcium activated potassium channel	0.0046	0.0478	0.0789
Echinococcus granulosus	neurogenic locus notch protein 4	0.0028	0.016	0.0258
Echinococcus multilocularis	slit 2 protein	0.0028	0.016	0.0258
Brugia malayi	Blistered cuticle protein 3	0.0055	0.0627	0.0622
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0033	0.0248	0.0243
Echinococcus multilocularis	Mastin	0.0024	0.0097	0.0152
Brugia malayi	Steroid receptor seven-up type 2	0.0033	0.0248	0.0243
Plasmodium falciparum	endoplasmin, putative	0.0041	0.0389	0.1967
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0033	0.0248	0.0817
Plasmodium vivax	heat shock protein 90, putative	0.0028	0.0157	0.0775
Schistosoma mansoni	notch	0.0028	0.016	0.052
Echinococcus multilocularis	protein jagged 2	0.0028	0.016	0.0258
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0033	0.0248	0.0817
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0627	0.0622
Onchocerca volvulus		0.0024	0.0097	0.0298
Echinococcus granulosus	delta-like protein 1	0.0028	0.016	0.0258
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0024	0.0097	0.0307
Trichomonas vaginalis	heat shock protein, putative	0.0053	0.0598	0.7182
Leishmania major	heat shock protein 83-1	0.0067	0.0831	0.4272
Schistosoma mansoni	hypothetical protein	0.0028	0.016	0.052
Brugia malayi	Nuclear hormone receptor-like 1	0.0033	0.0248	0.0243
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Trichomonas vaginalis	CMGC family protein kinase	0.0054	0.0606	0.728
Entamoeba histolytica	heat shock protein 90, putative	0.0067	0.0831	0.7423
Trichomonas vaginalis	CMGC family protein kinase	0.0054	0.0606	0.728
Schistosoma mansoni	hypothetical protein	0.0077	0.1003	0.3351
Brugia malayi	Animal haem peroxidase family protein	0.0055	0.0627	0.0622
Echinococcus multilocularis	enteropeptidase	0.0024	0.0097	0.0152
Brugia malayi	nuclear hormone receptor	0.0033	0.0248	0.0243
Onchocerca volvulus	Chorion peroxidase homolog	0.0055	0.0627	0.2827
Trypanosoma cruzi	Heat shock protein 83, putative	0.0067	0.0831	0.4272
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Loa Loa (eye worm)	animal heme peroxidase	0.0055	0.0627	0.0622
Brugia malayi	Endoplasmin precursor	0.0067	0.0831	0.0826
Toxoplasma gondii	subtilisin SUB12	0.002	0.0034	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0144	0.2131	0.2127
Loa Loa (eye worm)	hypothetical protein	0.003	0.0202	0.0197
Loa Loa (eye worm)	heat shock protein 75	0.0028	0.0157	0.0151
Trypanosoma brucei	heat shock protein, putative	0.0067	0.0831	0.4257
Echinococcus granulosus	protein jagged 2	0.0028	0.016	0.0258
Toxoplasma gondii	heat shock protein 75, putative	0.0028	0.0157	0.0299
Plasmodium vivax	hypothetical protein, conserved	0.0133	0.1957	1
Echinococcus granulosus	heat shock protein 90	0.0053	0.0598	0.0989
Onchocerca volvulus	Neurogenic locus notch homolog	0.0028	0.0162	0.0612
Schistosoma mansoni	serine/threonine protein kinase	0.0054	0.0606	0.2019
Loa Loa (eye worm)	hypothetical protein	0.0028	0.016	0.0155
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0033	0.0248	0.0406
Onchocerca volvulus	Peroxidasin homolog	0.0055	0.0627	0.2827
Brugia malayi	PAN domain containing protein	0.002	0.0034	0.0029
Schistosoma mansoni	hypothetical protein	0.0133	0.1957	0.6558
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0063	0.0756	0.3847
Loa Loa (eye worm)	heat shock protein 90	0.0067	0.0831	0.0826
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0033	0.0248	0.0243
Loa Loa (eye worm)	PAN domain-containing protein	0.002	0.0034	0.0029
Schistosoma mansoni	peroxidasin	0.0055	0.0627	0.2089
Echinococcus multilocularis	fibropellin Ia	0.0028	0.016	0.0258
Loa Loa (eye worm)	CMGC/MAPK/P38 protein kinase	0.0133	0.1945	0.1941
Echinococcus granulosus	heat shock protein heat shock protein 90 alpha	0.0053	0.0598	0.0989
Echinococcus granulosus	notch	0.0028	0.016	0.0258
Echinococcus multilocularis	transmembrane protease serine 3	0.0024	0.0097	0.0152
Onchocerca volvulus		0.0055	0.0627	0.2827
Onchocerca volvulus	Neurogenic locus notch protein homolog	0.0028	0.016	0.0601

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3339384

Bibliographic References

No literature references available for this target.

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Detailed information for compound 934001