Detailed information for compound 940530

Basic information

Technical information
  • TDR Targets ID: 940530
  • Name: (2S)-5,7-dimethoxy-2-phenylchroman-4-one
  • MW: 284.307 | Formula: C17H16O4
  • H donors: 0 H acceptors: 1 LogP: 2.85 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2O[C@@H](CC(=O)c2c(c1)OC)c1ccccc1
  • InChi: 1S/C17H16O4/c1-19-12-8-15(20-2)17-13(18)10-14(21-16(17)9-12)11-6-4-3-5-7-11/h3-9,14H,10H2,1-2H3/t14-/m0/s1
  • InChiKey: IAFBOKYTDSDNHV-AWEZNQCLSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-5,7-dimethoxy-2-phenyl-chroman-4-one
  • (2S)-5,7-dimethoxy-2-phenyl-4-chromanone
  • ZINC00058119

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0023 0.0137 1
Brugia malayi RING finger protein 20 0.0017 0.0068 0.0022
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0137 0.0091
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Leishmania major DNA repair protein-like protein 0.0017 0.0068 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0137 0.0091
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Schistosoma mansoni zinc finger protein 0.0331 0.3483 0.3474
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0137 0.0123
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0331 0.3483 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0331 0.3483 1
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0137 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0331 0.3483 0.3474
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0123
Schistosoma mansoni hypothetical protein 0.0017 0.0068 0.0054
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Brugia malayi PXA domain containing protein 0.0023 0.0137 0.0091
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Schistosoma mansoni hypothetical protein 0.0017 0.0068 0.0054
Echinococcus granulosus cell growth regulator with ring finger domain 0.0017 0.0068 0.0054
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0017 0.0068 0.0054
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0331 0.3483 0.3474
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0046 0.0046
Plasmodium vivax hypothetical protein, conserved 0.0931 1 1
Brugia malayi hypothetical protein 0.0023 0.0137 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0331 0.3483 1
Trypanosoma cruzi hypothetical protein, conserved 0.0331 0.3483 1
Plasmodium falciparum trophozoite exported protein 1 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0931 1 1
Entamoeba histolytica SPRY domain protein 0.0017 0.0068 0.4407
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0017 0.0068 0.0022
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0931 1 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0137 0.0123
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Chlamydia trachomatis SWIB complex protein 0.0931 1 0.5
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Toxoplasma gondii helicase, putative 0.0017 0.0068 0.0054
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0137 0.0137
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0931 1 1
Brugia malayi Zinc finger, C2H2 type family protein 0.0017 0.0068 0.0022
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0046 0.0093
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0017 0.0068 0.0155
Entamoeba histolytica hypothetical protein 0.0023 0.0137 1
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0331 0.3483 0.3474
Schistosoma mansoni mind bomb 0.0017 0.0068 0.0054
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0331 0.3483 1
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0046 0.0046
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0137 0.0091
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0123
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0137 0.0123
Toxoplasma gondii RING zinc finger protein 0.0017 0.0068 0.0054
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0017 0.0068 0.0054
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0137 0.0137
Brugia malayi PXA domain containing protein 0.0023 0.0137 0.0091
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Echinococcus granulosus RING finger protein 185 0.0017 0.0068 0.0054
Trypanosoma brucei predicted zinc finger protein 0.0017 0.0068 0.0155
Onchocerca volvulus 0.0331 0.3483 0.3438
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0137 0.0123
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0331 0.3483 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0137 0.0123
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Echinococcus granulosus ring finger protein 113a 0.0017 0.0068 0.0054
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Schistosoma mansoni hypothetical protein 0.0931 1 1
Echinococcus granulosus SWI:SNF matrix associated 0.0931 1 1
Schistosoma mansoni ring finger protein 151 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Brugia malayi Zinc finger protein 183 homolog 0.0017 0.0068 0.0022
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Echinococcus granulosus ring and YY1 binding protein 0.0331 0.3483 0.3474
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0137 0.0123
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Echinococcus multilocularis expressed protein 0.0451 0.4783 0.4775
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Echinococcus granulosus zinc finger protein Ran binding 0.0331 0.3483 0.3474
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0137 0.0091
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0931 1 1
Loa Loa (eye worm) brahma associated protein 0.0931 1 1
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0331 0.3483 0.3474
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0331 0.3483 0.3438
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Onchocerca volvulus 0.0331 0.3483 0.3438
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0137 0.0123
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0331 0.3483 1
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0137 0.0137
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0017 0.0068 0.0054
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Plasmodium falciparum zinc finger protein, putative 0.0017 0.0068 0.0054
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Leishmania major hypothetical protein 0.0017 0.0068 0.0155
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0137 0.0091
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0137 0.0123
Giardia lamblia Zinc finger domain 0.0017 0.0068 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0017 0.0068 0.0054
Echinococcus multilocularis SWI:SNF matrix associated 0.0931 1 1
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0017 0.0068 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi YY1-associated factor 2 0.0331 0.3483 0.3453
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0137 0.0123
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Brugia malayi SWIB/MDM2 domain containing protein 0.0931 1 1
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi hypothetical protein 0.0023 0.0137 0.0091
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0137 0.0123
Giardia lamblia Kinase 0.0017 0.0068 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni hypothetical protein 0.0331 0.3483 0.3474
Schistosoma mansoni hypothetical protein 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0137 0.0123
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0123
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0137 0.0123
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Giardia lamblia Ribonuclease 0.0017 0.0068 1
Echinococcus multilocularis ring and YY1 binding protein 0.0331 0.3483 0.3474
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0406 0.0393
Echinococcus multilocularis ring finger protein 170 0.0017 0.0068 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0068 0.0054
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0931 1 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Onchocerca volvulus 0.0931 1 1
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni hypothetical protein 0.0931 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0406 0.0406
Giardia lamblia Kinase, NEK 0.0017 0.0068 1
Onchocerca volvulus 0.0331 0.3483 0.3438
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0017 0.0068 0.0054
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Trypanosoma cruzi hypothetical protein 0.0017 0.0068 0.0155
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Brugia malayi B-box zinc finger family protein 0.0017 0.0068 0.0022
Brugia malayi brahma associated protein 60 kDa 0.0931 1 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Giardia lamblia Kinase, NEK 0.0017 0.0068 1
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Echinococcus multilocularis ring finger protein 113a 0.0017 0.0068 0.0054
Onchocerca volvulus 0.0048 0.0406 0.034
Chlamydia trachomatis DNA topoisomerase I 0.0931 1 0.5
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0017 0.0068 0.0054
Plasmodium vivax DNA repair protein RAD5, putative 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0017 0.0068 0.0155
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0017 0.0068 0.0054
Echinococcus granulosus tumor protein p63 0.0328 0.3446 0.3437
Schistosoma mansoni brg-1 associated factor 0.0931 1 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Echinococcus granulosus expressed protein 0.0451 0.4783 0.4775
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0137 0.0123
Trypanosoma brucei ring finger containing protein 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Schistosoma mansoni zinc finger protein 0.0017 0.0068 0.0054
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0331 0.3483 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Trypanosoma brucei DNA repair protein, putative 0.0017 0.0068 0.0155
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0137 0.0123
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0137 0.0123
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0137 0.0123
Echinococcus multilocularis 0.0017 0.0068 0.0054
Echinococcus multilocularis SWI:SNF matrix associated 0.0931 1 1
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Echinococcus multilocularis RING finger protein 185 0.0017 0.0068 0.0054
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Ser/Thr protein kinase 0.0017 0.0068 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0331 0.3483 0.3474
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0331 0.3483 1
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0331 0.3483 1
Loa Loa (eye worm) RING finger protein 20 0.0017 0.0068 0.0068
Plasmodium falciparum RING zinc finger protein, putative 0.0017 0.0068 0.0054
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0017 0.0068 0.0054
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0017 0.0068 0.0054
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0137 0.0123
Loa Loa (eye worm) RiNg Finger protein family member 0.0017 0.0068 0.0068
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0017 0.0068 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0137 0.0123
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Schistosoma mansoni peter pan-related 0.0017 0.0068 0.0054
Schistosoma mansoni rnf5 0.0017 0.0068 0.0054
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni fusion 0.0331 0.3483 0.3474
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Plasmodium vivax RING zinc finger protein, putative 0.0017 0.0068 0.0054
Echinococcus granulosus Zinc finger RanBP2 type 0.0331 0.3483 0.3474
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0137 0.0137
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0137 0.0123
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0017 0.0068 0.0054
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Trichomonas vaginalis conserved hypothetical protein 0.0931 1 1
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0931 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0331 0.3483 1
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0017 0.0068 0.0155
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0931 1 1
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi RING zinc finger protein 0.0017 0.0068 0.0022
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0017 0.0068 0.0054
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0137 0.0123
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Schistosoma mansoni RNA binding protein 0.0331 0.3483 0.3474
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0015 0.0046 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0137 0.0123
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Entamoeba histolytica hypothetical protein 0.0017 0.0068 0.4407
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0017 0.0068 0.0054
Schistosoma mansoni peter pan-related 0.0017 0.0068 0.0054
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Leishmania major hypothetical protein, unknown function 0.0017 0.0068 0.0155
Echinococcus granulosus ring finger protein 170 0.0017 0.0068 0.0054
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Plasmodium vivax zinc finger protein, putative 0.0017 0.0068 0.0054
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0331 0.3483 1
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0046 0.0093
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Brugia malayi Neuralized family protein 0.0017 0.0068 0.0022
Toxoplasma gondii ran binding protein 0.0331 0.3483 0.3474
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0137 0.0123
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Trypanosoma cruzi hypothetical protein 0.0017 0.0068 0.0155
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0137 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Echinococcus multilocularis SWI:SNF matrix associated 0.0931 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Echinococcus multilocularis tumor protein p63 0.0328 0.3446 0.3437
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0017 0.0068 0.0054
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0137 0.0123
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0046 0.0046
Plasmodium vivax trophozoite exported protein 1, putative 0.0017 0.0068 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0331 0.3483 1
Leishmania major cytochrome p450-like protein 0.0015 0.0046 0.0093
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0017 0.0068 0.0054
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0046 0.0093
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0137 0.0123
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0931 1 1
Entamoeba histolytica hypothetical protein 0.0023 0.0137 1
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0017 0.0068 0.0054
Giardia lamblia Zinc finger domain 0.0017 0.0068 1
Echinococcus multilocularis zinc finger protein Ran binding 0.0331 0.3483 0.3474
Schistosoma mansoni TRABID protein (C64 family) 0.0331 0.3483 0.3474
Trypanosoma cruzi WLM domain containing protein, putative 0.0331 0.3483 1
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Schistosoma mansoni hypothetical protein 0.0931 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Onchocerca volvulus 0.0331 0.3483 0.3438
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0137 0.0123
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0017 0.0068 0.0155
Entamoeba histolytica hypothetical protein 0.0017 0.0068 0.4407

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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