Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | DNA-binding protein D-ETS-3 | 0.0011 | 0.0112 | 0.0211 |
Leishmania major | small ubiquitin protein, putative | 0.0031 | 0.061 | 0.6366 |
Echinococcus multilocularis | caspase 2 | 0.0032 | 0.0615 | 0.0588 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 0.0958 | 1 |
Toxoplasma gondii | small ubiquitin family modifier, putative | 0.0031 | 0.061 | 0.5074 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0958 | 0.1813 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0054 | 0.0102 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0034 | 0.0676 | 0.5625 |
Loa Loa (eye worm) | D-ets-2 protein | 0.0011 | 0.0112 | 0.0211 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0117 | 0.1562 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0032 | 0.0615 | 0.0588 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0676 | 0.1634 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0034 | 0.0676 | 0.5 |
Brugia malayi | pyruvate kinase | 0.0007 | 0.0026 | 0.0049 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.0011 | 0.0112 | 0.0211 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0329 | 0.3432 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0658 | 0.9707 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0105 | 0.0076 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0105 | 0.0076 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0329 | 0.0329 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.001 | 0.0103 | 0.5 |
Loa Loa (eye worm) | SMO-1 protein | 0.0031 | 0.061 | 0.1154 |
Brugia malayi | Fli-1 protein | 0.0225 | 0.5283 | 1 |
Plasmodium vivax | small ubiquitin-related modifier, putative | 0.0031 | 0.061 | 0.902 |
Echinococcus multilocularis | Eukaryotic translation initiation factor 4H | 0.0138 | 0.3182 | 0.3162 |
Echinococcus multilocularis | smad | 0.0008 | 0.0054 | 0.0025 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0105 | 0.0105 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0105 | 0.0076 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0105 | 0.0076 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0034 | 0.0676 | 0.128 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.0677 | 0.065 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0658 | 0.6865 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0105 | 0.0198 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0054 | 0.0102 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.2814 | 0.5327 |
Schistosoma mansoni | rotamase | 0.0034 | 0.0677 | 0.0677 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0605 | 0.0578 |
Onchocerca volvulus | 0.003 | 0.0565 | 0.1315 | |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0112 | 0.0211 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0329 | 0.3432 |
Echinococcus granulosus | Small ubiquitin modifier 2 | 0.0031 | 0.061 | 0.0582 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0011 | 0.0112 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.3182 | 0.6023 |
Echinococcus multilocularis | pyruvate kinase | 0.0018 | 0.0275 | 0.0247 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0615 | 0.1165 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0676 | 0.128 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0105 | 0.0198 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | pyruvate kinase | 0.0018 | 0.0275 | 0.0247 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0024 | 0.0427 | 0.5727 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0105 | 0.0198 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0054 | 0.0102 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0105 | 0.0105 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0105 | 0.0198 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.0629 | 0.6568 |
Loa Loa (eye worm) | fli-1 protein | 0.0225 | 0.5283 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.2814 | 0.5327 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0054 | 0.0054 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0605 | 0.0605 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.007 | 0.0132 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0105 | 0.0198 |
Onchocerca volvulus | 0.0011 | 0.0117 | 0.0036 | |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0105 | 0.0198 |
Giardia lamblia | Pyruvate kinase | 0.0018 | 0.0275 | 0.4067 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Schistosoma mansoni | smad | 0.0008 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0615 | 0.1165 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0054 | 0.0102 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0054 | 0.0025 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0105 | 0.0198 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0329 | 0.3432 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.001 | 0.0103 | 0.1074 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0105 | 0.0076 |
Brugia malayi | Cell death protein 3 precursor | 0.0032 | 0.0615 | 0.1165 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.0011 | 0.0112 | 0.0083 |
Echinococcus multilocularis | dna polymerase eta | 0.0046 | 0.0958 | 0.0932 |
Echinococcus granulosus | pyruvate kinase | 0.0018 | 0.0275 | 0.0247 |
Echinococcus multilocularis | ubiquitin | 0.0011 | 0.0117 | 0.0088 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0105 | 0.0198 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0105 | 0.0105 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0112 | 0.0083 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0565 | 0.1069 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.0011 | 0.0112 | 0.0083 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.0658 | 0.5472 |
Plasmodium falciparum | small ubiquitin-related modifier | 0.0031 | 0.061 | 0.902 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0676 | 0.0649 |
Trypanosoma cruzi | small ubiquitin protein, putative | 0.0031 | 0.061 | 0.6366 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0105 | 0.0198 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0181 | 0.1887 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0105 | 0.0076 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0105 | 0.0105 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0105 | 0.0076 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0054 | 0.0102 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.0677 | 0.1282 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.1202 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0105 | 0.0076 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0112 | 0.0083 |
Giardia lamblia | Pyruvate kinase | 0.0034 | 0.0676 | 1 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.0677 | 0.065 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0105 | 0.0076 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0105 | 0.0076 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0677 | 1 |
Mycobacterium ulcerans | pyruvate kinase | 0.0034 | 0.0676 | 1 |
Trypanosoma cruzi | small ubiquitin protein, putative | 0.0031 | 0.061 | 0.6366 |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0676 | 0.128 |
Onchocerca volvulus | 0.0032 | 0.0615 | 0.1461 | |
Loa Loa (eye worm) | pyruvate kinase | 0.0034 | 0.0676 | 0.128 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0011 | 0.0112 | 0.0112 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0029 | 0.0029 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0054 | 0.0102 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.0011 | 0.0112 | 0.0083 |
Onchocerca volvulus | 0.0156 | 0.3601 | 1 | |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0054 | 0.0025 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0105 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0105 | 0.0076 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0024 | 0.0427 | 0.0808 |
Echinococcus multilocularis | pyruvate kinase | 0.0018 | 0.0275 | 0.0247 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0074 | 0.1641 | 0.1616 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0658 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 0.0958 | 1 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.0676 | 0.7057 |
Brugia malayi | RNA binding protein | 0.0138 | 0.3182 | 0.6023 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0105 | 0.0198 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0329 | 0.0329 |
Brugia malayi | hypothetical protein | 0.0156 | 0.3601 | 0.6816 |
Echinococcus granulosus | dna polymerase eta | 0.0046 | 0.0958 | 0.0932 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1381 | 0.2615 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0105 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0046 | 0.0958 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0054 | 0.0054 |
Echinococcus multilocularis | ets variant gene 4 | 0.0011 | 0.0112 | 0.0083 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0105 | 0.0198 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0181 | 0.1887 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0329 | 0.0301 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0421 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0112 | 0.0211 |
Schistosoma mansoni | eukaryotic translation initiation factor 4h | 0.0138 | 0.3182 | 0.3182 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0329 | 0.4751 |
Chlamydia trachomatis | pyruvate kinase | 0.0034 | 0.0676 | 0.5 |
Echinococcus multilocularis | pyruvate kinase | 0.0027 | 0.0502 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0117 | 0.0222 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0105 | 0.0198 |
Echinococcus multilocularis | Small ubiquitin modifier 2 | 0.0031 | 0.061 | 0.0582 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0032 | 0.0615 | 0.0588 |
Plasmodium vivax | pyruvate kinase, putative | 0.0034 | 0.0676 | 1 |
Echinococcus granulosus | ubiquitin | 0.0011 | 0.0117 | 0.0088 |
Brugia malayi | Ubiquitin-like protein SMT3 | 0.0031 | 0.061 | 0.1154 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.0011 | 0.0112 | 0.0083 |
Schistosoma mansoni | gabp alpha | 0.0074 | 0.1641 | 0.1641 |
Schistosoma mansoni | hypothetical protein | 0.0421 | 1 | 1 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0034 | 0.0676 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0054 | 0.0054 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0105 | 0.0198 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, putative | 0.001 | 0.0103 | 0.1074 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0565 | 0.1069 |
Schistosoma mansoni | ets-related | 0.0225 | 0.5283 | 0.5283 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0105 | 0.0076 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0072 | 0.0044 |
Brugia malayi | Ets-domain containing protein | 0.0074 | 0.1641 | 0.3106 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0676 | 0.0649 |
Echinococcus multilocularis | protein C ets 2 | 0.0011 | 0.0112 | 0.0083 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.0011 | 0.0112 | 0.0083 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0074 | 0.1641 | 0.1616 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0329 | 0.4863 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0046 | 0.0958 | 0.1813 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0676 | 0.1634 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0329 | 0.4863 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0105 | 0.0076 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Trypanosoma brucei | small ubiquitin-related modifier | 0.0031 | 0.061 | 0.6366 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0032 | 0.0629 | 0.5235 |
Plasmodium falciparum | pyruvate kinase | 0.0034 | 0.0676 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0105 | 0.0198 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0676 | 0.0676 |
Brugia malayi | transcription factor E74 isoform | 0.0011 | 0.0112 | 0.0211 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0605 | 0.0578 |
Echinococcus granulosus | protein C ets 2 | 0.0011 | 0.0112 | 0.0083 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.0011 | 0.0112 | 0.0083 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0032 | 0.0615 | 0.1461 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0018 | 0.0275 | 0.4067 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0105 | 0.0198 |
Entamoeba histolytica | ubiquitin like protein | 0.0031 | 0.061 | 0.9115 |
Schistosoma mansoni | eukaryotic translation initiation factor 4h | 0.0138 | 0.3182 | 0.3182 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0105 | 0.0105 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0105 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0615 | 0.1165 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.0658 | 0.6865 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0034 | 0.0676 | 0.7057 |
Echinococcus granulosus | pyruvate kinase | 0.0018 | 0.0275 | 0.0247 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.0011 | 0.0112 | 0.0083 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0181 | 0.1887 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0676 | 0.0649 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0329 | 0.0622 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0615 | 0.0615 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0105 | 0.0076 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0105 | 0.0076 |
Schistosoma mansoni | DNA polymerase eta | 0.0046 | 0.0958 | 0.0958 |
Schistosoma mansoni | ets | 0.0011 | 0.0112 | 0.0112 |
Schistosoma mansoni | pyruvate kinase | 0.0018 | 0.0275 | 0.0275 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Echinococcus granulosus | caspase 2 | 0.0032 | 0.0615 | 0.0588 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0112 | 0.0112 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0181 | 0.1887 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0105 | 0.0198 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.001 | 0.0101 | 0.0192 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.0677 | 1 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0034 | 0.0676 | 0.1634 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0329 | 0.0622 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Leishmania major | pyruvate kinase | 0.0034 | 0.0676 | 0.7057 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0054 | 0.0102 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0329 | 0.0301 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0329 | 0.0301 |
Echinococcus multilocularis | pyruvate kinase | 0.0018 | 0.0275 | 0.0247 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0054 | 0.0025 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0054 | 0.0025 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0105 | 0.0105 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0112 | 0.0083 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0105 | 0.0076 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0181 | 0.1887 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0105 | 0.0105 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0329 | 0.4863 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0105 | 0.0198 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0105 | 0.0198 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0034 | 0.0676 | 0.9984 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0677 | 0.1282 |
Schistosoma mansoni | ubiquitin-like protein sumo/smt3-related | 0.0031 | 0.061 | 0.061 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.001 | 0.0103 | 0.1074 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0658 | 0.6865 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0034 | 0.0676 | 0.7057 |
Schistosoma mansoni | ets-related | 0.0011 | 0.0112 | 0.0112 |
Giardia lamblia | Sentrin | 0.0031 | 0.061 | 0.902 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0105 | 0.0105 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0032 | 0.0615 | 0.0615 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.2814 | 0.5327 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0105 | 0.0105 |
Brugia malayi | pyruvate kinase, muscle isozyme | 0.0007 | 0.0026 | 0.0049 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.1363 | 0.1363 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0105 | 0.0105 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0105 | 0.0198 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0112 | 0.0112 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0329 | 0.3432 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0018 | 0.0275 | 0.2288 |
Brugia malayi | Smad1 | 0.0008 | 0.0054 | 0.0102 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0329 | 0.0301 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0605 | 0.0605 |
Loa Loa (eye worm) | pyruvate kinase | 0.0007 | 0.0026 | 0.0049 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0329 | 0.3915 |
Schistosoma mansoni | elf1 | 0.0011 | 0.0112 | 0.0112 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0054 | 0.0054 |
Trichomonas vaginalis | ubiquitin, putative | 0.0011 | 0.0117 | 0.1562 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.001 | 0.0103 | 0.1074 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.061 | 0.8986 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0018 | 0.0275 | 0.4067 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0105 | 0.0076 |
Leishmania major | pyruvate kinase | 0.0034 | 0.0676 | 0.7057 |
Toxoplasma gondii | PPIC-type PPIASE domain-containing protein | 0.001 | 0.0103 | 0.0856 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0676 | 0.0676 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0034 | 0.0676 | 0.9984 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0427 | 0.0808 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0117 | 0.0222 |
Brugia malayi | Ets-domain containing protein | 0.0011 | 0.0112 | 0.0211 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0074 | 0.1641 | 0.3106 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0054 | 0.0025 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0072 | 0.0137 |
Schistosoma mansoni | eukaryotic translation initiation factor 4h | 0.0138 | 0.3182 | 0.3182 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0329 | 0.4751 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0112 | 0.0083 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0034 | 0.0676 | 0.7057 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.3601 | 0.6816 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | Eukaryotic translation initiation factor 4H | 0.0138 | 0.3182 | 0.3162 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0329 | 0.3432 |
Brugia malayi | Ets-domain containing protein | 0.0074 | 0.1641 | 0.3106 |
Echinococcus granulosus | smad | 0.0008 | 0.0054 | 0.0025 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.0011 | 0.0112 | 0.0211 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0105 | 0.0105 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0054 | 0.0025 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0072 | 0.0044 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0329 | 0.3432 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.0011 | 0.0112 | 0.0083 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0676 | 0.0649 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0105 | 0.0198 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0105 | 0.0076 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.0658 | 0.6865 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.0629 | 0.6568 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0676 | 0.128 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0034 | 0.0676 | 0.128 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.