Detailed information for compound 1047206

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.878 | Formula: C17H30ClNO3
  • H donors: 1 H acceptors: 1 LogP: 4.65 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCOc1cc(CN(C)C)cc(c1O)OCCCC.Cl
  • InChi: 1S/C17H29NO3.ClH/c1-5-7-9-20-15-11-14(13-18(3)4)12-16(17(15)19)21-10-8-6-2;/h11-12,19H,5-10,13H2,1-4H3;1H
  • InChiKey: CUDFMGZPWOQTNF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0025 0.0226
Loa Loa (eye worm) hypothetical protein 0.0037 0.0002 0.0012
Toxoplasma gondii NADPH-glutathione reductase 0.005 0.0015 0.0014
Onchocerca volvulus Alhambra homolog 0.0116 0.0084 0.2157
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0038 0.0002 0.0001
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.026 0.0234 0.2148
Schistosoma mansoni hypothetical protein 0.0176 0.0146 0.1339
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0012 0.0112
Onchocerca volvulus 0.034 0.0317 0.8223
Mycobacterium tuberculosis Probable dehydrogenase 0.0331 0.0308 0.0307
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Brugia malayi AF-10 protein 0.0038 0.0002 0.0035
Leishmania major trypanothione reductase 0.0145 0.0114 0.0299
Schistosoma mansoni rab6-interacting 0.034 0.0317 0.2908
Echinococcus multilocularis adam 17 protease 0.0414 0.0395 0.3625
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0015 0.0038
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.005 0.0015 0.0014
Echinococcus multilocularis geminin 0.0176 0.0146 0.1346
Brugia malayi Matrixin family protein 0.0183 0.0153 0.3608
Echinococcus granulosus phd:f box containing protein 0.0037 0.0002 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.001 0.008
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0183 0.0153 0.1402
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0116 0.0084 0.0763
Schistosoma mansoni hypothetical protein 0.009 0.0057 0.0511
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0012 0.0103
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0012 0.0112
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.0206 0.0205
Loa Loa (eye worm) hypothetical protein 0.0049 0.0014 0.0148
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0015 0.0038
Plasmodium vivax multidomain scavenger receptor, putative 0.034 0.0317 0.0316
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0331 0.0308 0.0307
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Giardia lamblia PHD finger protein 15 0.0116 0.0084 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0019 0.0428
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.005 0.0015 0.0014
Trypanosoma cruzi trypanothione reductase, putative 0.0145 0.0114 0.0299
Loa Loa (eye worm) hypothetical protein 0.004 0.0004 0.004
Brugia malayi hypothetical protein 0.0072 0.0038 0.0875
Leishmania major polypeptide deformylase-like protein, putative 0.3673 0.3793 1
Echinococcus granulosus lysine specific demethylase 5A 0.0142 0.0111 0.1023
Echinococcus multilocularis jumonji domain containing 1A 0.0037 0.0002 0.0018
Plasmodium vivax glutathione reductase, putative 0.0145 0.0114 0.0113
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0368 0.0347 0.0346
Echinococcus granulosus geminin 0.0176 0.0146 0.1346
Toxoplasma gondii PHD-finger domain-containing protein 0.0116 0.0084 0.0083
Loa Loa (eye worm) MBCTL1 0.0054 0.0019 0.0208
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0037 0.0002 0.0001
Brugia malayi Thioredoxin reductase 0.0145 0.0114 0.268
Brugia malayi jmjC domain containing protein 0.0142 0.0111 0.2612
Trypanosoma cruzi Peptide deformylase 2, putative 0.3673 0.3793 1
Plasmodium falciparum thioredoxin reductase 0.005 0.0015 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Brugia malayi hypothetical protein 0.034 0.0317 0.7482
Loa Loa (eye worm) hypothetical protein 0.0054 0.0019 0.0208
Echinococcus granulosus jumonji domain containing protein 0.0161 0.0131 0.1206
Onchocerca volvulus Matrilysin homolog 0.0405 0.0385 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.0153 0.1754
Onchocerca volvulus 0.0183 0.0153 0.3965
Trypanosoma cruzi Peptide deformylase 2, putative 0.3673 0.3793 1
Loa Loa (eye worm) matrixin family protein 0.0442 0.0424 0.4863
Trypanosoma brucei Peptide deformylase 2 0.3673 0.3793 1
Plasmodium falciparum glutathione reductase 0.005 0.0015 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0037 0.0002 0.0003
Echinococcus granulosus RUN 0.034 0.0317 0.2914
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0015 0.0038
Echinococcus multilocularis jumonji domain containing protein 0.0161 0.0131 0.1206
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0038 0.0002 0.0004
Brugia malayi jmjC domain containing protein 0.0037 0.0002 0.0024
Onchocerca volvulus 0.034 0.0317 0.8223
Leishmania major acetoin dehydrogenase e3 component-like protein 0.005 0.0015 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.005 0.0015 0.0014
Brugia malayi Matrixin family protein 0.0183 0.0153 0.3608
Echinococcus multilocularis Polycystic kidney disease protein 0.034 0.0317 0.2914
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.005 0.0015 0.0038
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0223 0.0195 0.0194
Schistosoma mansoni loxhd1 0.034 0.0317 0.2908
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0002 0.0001
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0195 0.0167 0.1525
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0001 0.0008
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0012 0.0129
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0019 0.0174
Brugia malayi Bromodomain containing protein 0.0074 0.004 0.0934
Echinococcus multilocularis thioredoxin glutathione reductase 0.0145 0.0114 0.1049
Plasmodium falciparum glutathione reductase 0.0145 0.0114 0.0112
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0001 0.0008
Schistosoma mansoni jumonji domain containing protein 0.0037 0.0002 0.0009
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0012 0.0293
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0002 0.0012
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.005 0.0015 0.0014
Echinococcus granulosus adam 17 protease 0.0455 0.0438 0.4021
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0012 0.0103
Loa Loa (eye worm) hypothetical protein 0.034 0.0317 0.3638
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0025 0.0226
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0019 0.0174
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0186 0.0157 0.1444
Plasmodium vivax JmjC domain containing protein 0.0037 0.0002 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0015 0.0038
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0012 0.0112
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.005 0.0015 0.0014
Echinococcus granulosus lysine specific demethylase 6a 0.0037 0.0002 0.0018
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0843 0.0842 0.7732
Echinococcus granulosus lipoxygenase domain containing protein 0.034 0.0317 0.2914
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0141 0.011 0.1005
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.3673 0.3793 1
Brugia malayi Disintegrin family protein 0.0041 0.0006 0.0118
Echinococcus multilocularis peregrin 0.0118 0.0086 0.0793
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.005 0.0015 0.0141
Schistosoma mansoni lipoxygenase 0.1079 0.1088 1
Brugia malayi jmjC domain containing protein 0.0037 0.0002 0.0024
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.001 0.0206
Schistosoma mansoni rab6-interacting 0.034 0.0317 0.2908
Mycobacterium tuberculosis Possible exported protein 0.0497 0.0481 0.048
Mycobacterium tuberculosis Probable reductase 0.0331 0.0308 0.0307
Echinococcus multilocularis adam 0.0072 0.0038 0.0348
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.9626 1 1
Schistosoma mansoni hypothetical protein 0.0038 0.0002 0.0014
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0664 0.0656 0.6024
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.001 0.01
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0037 0.0002 0.0009
Echinococcus granulosus peregrin 0.0118 0.0086 0.0793
Schistosoma mansoni jumonji/arid domain-containing protein 0.0142 0.0111 0.1015
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0002 0.0012
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.005 0.0015 0.0038
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0072 0.0038 0.034
Echinococcus multilocularis snurportin 1 0.034 0.0317 0.2913
Brugia malayi mbt repeat family protein 0.0047 0.0012 0.0266
Brugia malayi glutathione reductase 0.0145 0.0114 0.268
Loa Loa (eye worm) hypothetical protein 0.007 0.0036 0.0403
Echinococcus multilocularis disintegrin and metalloproteinase 0.0041 0.0006 0.0054
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.026 0.0234 0.2148
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0331 0.0308 0.0307
Schistosoma mansoni dihydroceramide desaturase 0.0041 0.0006 0.0046
Mycobacterium ulcerans flavoprotein disulfide reductase 0.005 0.0015 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.001 0.008
Loa Loa (eye worm) jmjC domain-containing protein 0.0142 0.0111 0.127
Echinococcus granulosus thioredoxin glutathione reductase 0.0145 0.0114 0.1049
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.0001 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.001 0.0088
Trypanosoma brucei trypanothione reductase 0.0145 0.0114 0.0299
Mycobacterium ulcerans hydrolase 0.0223 0.0195 0.0194
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0145 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.034 0.0317 0.3638
Schistosoma mansoni hypothetical protein 0.0287 0.0263 0.2406
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.005 0.0015 0.0013
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0195 0.0167 0.3923
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0368 0.0347 0.0346
Schistosoma mansoni jumonji/arid domain-containing protein 0.0142 0.0111 0.1015
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0331 0.0308 0.0307
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.005 0.0015 0.0038
Echinococcus granulosus PHD finger protein rhinoceros 0.0116 0.0084 0.077
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0018
Schistosoma mansoni hypothetical protein 0.0116 0.0084 0.0763
Brugia malayi Bromodomain containing protein 0.0118 0.0086 0.202
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.3673 0.3793 1
Brugia malayi jmjC domain containing protein 0.0037 0.0002 0.0024
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0015 0.0038
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0012 0.0112
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.9626 1 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1079 0.1088 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Trichomonas vaginalis glutathione reductase, putative 0.005 0.0015 1
Loa Loa (eye worm) doublecortin family protein 0.034 0.0317 0.3638
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.001 0.008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.001 0.0088
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0037 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0116 0.0084 0.0954
Schistosoma mansoni hypothetical protein 0.0176 0.0146 0.1339
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0041 0.0006 0.0046
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.038 0.0359 0.33
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0041 0.0006 0.0054
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0331 0.0308 0.0307
Echinococcus granulosus Polycystic kidney disease protein 0.034 0.0317 0.2914
Echinococcus multilocularis RUN 0.034 0.0317 0.2914
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0037 0.0002 0.0003
Schistosoma mansoni phd/f-box containing protein 0.0037 0.0002 0.0009
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0195 0.0167 0.1532
Toxoplasma gondii PHD-finger domain-containing protein 0.0116 0.0084 0.0083
Onchocerca volvulus 0.0259 0.0233 0.6036
Brugia malayi Matrixin family protein 0.0183 0.0153 0.3608
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0015 0.0038
Loa Loa (eye worm) thioredoxin reductase 0.0145 0.0114 0.1303
Brugia malayi Matrixin family protein 0.0183 0.0153 0.3608
Echinococcus multilocularis PHD finger protein rhinoceros 0.0116 0.0084 0.077
Brugia malayi RNA, U transporter 1 0.009 0.0057 0.1332
Brugia malayi Hemopexin family protein 0.0259 0.0233 0.5492
Brugia malayi Matrixin family protein 0.0442 0.0424 1
Loa Loa (eye worm) hypothetical protein 0.0223 0.0195 0.2232
Brugia malayi mbt repeat family protein 0.0047 0.0012 0.0266
Schistosoma mansoni hypothetical protein 0.034 0.0317 0.2908
Mycobacterium leprae PROBABLE HYDROLASE 0.0223 0.0195 0.0194
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0041 0.0006 0.0054
Onchocerca volvulus Matrilysin homolog 0.0183 0.0153 0.3965
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0014 0.0305
Loa Loa (eye worm) glutathione reductase 0.0145 0.0114 0.1303
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0039 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0199 0.017 0.1949
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0186 0.0157 0.1444
Loa Loa (eye worm) jmjC domain-containing protein 0.024 0.0213 0.2437
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0014 0.0148
Plasmodium falciparum phd finger protein, putative 0.0116 0.0084 0.0082
Loa Loa (eye worm) hypothetical protein 0.0041 0.0006 0.0057
Echinococcus multilocularis lysine specific demethylase 6a 0.0037 0.0002 0.0018
Trichomonas vaginalis mercuric reductase, putative 0.005 0.0015 1
Schistosoma mansoni jumonji domain containing protein 0.0302 0.0278 0.2545
Brugia malayi PHD-finger family protein 0.0116 0.0084 0.1963
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0223 0.0195 0.459
Treponema pallidum polypeptide deformylase (def) 0.9626 1 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0368 0.0347 0.0346
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.034 0.0317 0.3637
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0069
Onchocerca volvulus Matrix metalloproteinase homolog 0.0405 0.0385 1
Schistosoma mansoni bromodomain containing protein 0.0063 0.0028 0.0252
Brugia malayi Doublecortin family protein 0.034 0.0317 0.7482
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.9626 1 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.038 0.0359 0.33
Schistosoma mansoni lipoxygenase 0.0468 0.0451 0.4136
Plasmodium vivax peptide deformylase, putative 0.9626 1 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0037 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.034 0.0317 0.2907
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0038 0.0002 0.0004
Toxoplasma gondii hypothetical protein 0.9626 1 1
Mycobacterium ulcerans peptide deformylase 0.9626 1 1
Schistosoma mansoni protein phosphatase 2C 0.0037 0.0002 0.0009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0014 0.0305
Brugia malayi F/Y-rich N-terminus family protein 0.004 0.0004 0.0082
Loa Loa (eye worm) hypothetical protein 0.0183 0.0153 0.1754
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0039 0.0004 0.0036
Trypanosoma brucei Polypeptide deformylase 1 0.3673 0.3793 1
Echinococcus multilocularis lysine specific demethylase 5A 0.014 0.0109 0.1004
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0019 0.0174
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1079 0.1088 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0002 0.0014
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.005 0.0015 0.0014
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.005 0.0015 0.0013
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0041 0.0006 0.0046
Loa Loa (eye worm) hypothetical protein 0.004 0.0005 0.0047
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.0001 0.0011
Echinococcus granulosus JmjC domain containing protein 4 0.0037 0.0002 0.0018
Echinococcus multilocularis phd:f box containing protein 0.0037 0.0002 0.0018
Onchocerca volvulus 0.0047 0.0012 0.0293
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.005 0.0015 0.0141
Plasmodium falciparum thioredoxin reductase 0.0145 0.0114 0.0112
Toxoplasma gondii thioredoxin reductase 0.0145 0.0114 0.0113
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0195 0.0167 0.1532
Echinococcus granulosus adam 0.0072 0.0038 0.0348
Schistosoma mansoni hypothetical protein 0.0259 0.0233 0.2134
Brugia malayi Bromodomain containing protein 0.0038 0.0002 0.0036
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0414 0.0395 0.362
Schistosoma mansoni phosphatidylserine receptor 0.0037 0.0002 0.0009
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0019 0.0166
Loa Loa (eye worm) reprolysin 0.0041 0.0006 0.0057
Echinococcus multilocularis lipoxygenase domain containing protein 0.034 0.0317 0.2914
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0019 0.0174
Echinococcus granulosus jumonji domain containing 1A 0.0037 0.0002 0.0018
Brugia malayi hypothetical protein 0.034 0.0317 0.7482
Trypanosoma brucei RNA helicase, putative 0.009 0.0057 0.0147
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0012 0.0103
Loa Loa (eye worm) hypothetical protein 0.087 0.087 1
Brugia malayi jmjC domain containing protein 0.0037 0.0002 0.0024
Schistosoma mansoni polycystin 1-related 0.034 0.0317 0.2908
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0664 0.0656 0.6024
Loa Loa (eye worm) PHD-finger family protein 0.0116 0.0084 0.0954
Echinococcus granulosus snurportin 1 0.034 0.0317 0.2913
Loa Loa (eye worm) hypothetical protein 0.0047 0.0012 0.0129
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0368 0.0347 0.0346
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0331 0.0308 0.0307
Echinococcus granulosus disintegrin and metalloproteinase 0.0041 0.0006 0.0054
Plasmodium falciparum peptide deformylase 0.9626 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0002 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0116 0.0084 0.0083
Brugia malayi PHD-finger family protein 0.004 0.0004 0.0082
Plasmodium vivax thioredoxin reductase, putative 0.0145 0.0114 0.0113
Echinococcus granulosus lipoxygenase domain containing protein 0.034 0.0317 0.2914
Echinococcus multilocularis lipoxygenase domain containing protein 0.034 0.0317 0.2914
Plasmodium falciparum LCCL domain-containing protein 0.034 0.0317 0.0315
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.001 0.0088
Toxoplasma gondii PHD-finger domain-containing protein 0.0038 0.0002 0.0001
Echinococcus multilocularis JmjC domain containing protein 4 0.0037 0.0002 0.0018
Loa Loa (eye worm) matrix metalloproteinase 0.0183 0.0153 0.1754
Leishmania major hypothetical protein, conserved 0.0037 0.0002 0.0003
Brugia malayi jmjC domain containing protein 0.038 0.0359 0.8476
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.001 0.0088
Loa Loa (eye worm) matrixin family protein 0.0405 0.0385 0.4425
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.005 0.0015 0.0341
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.005 0.0015 0.0132
Loa Loa (eye worm) hypothetical protein 0.0183 0.0153 0.1754

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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