Detailed information for compound 1160968

Basic information

Technical information
  • TDR Targets ID: 1160968
  • Name: 3-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-2-meth ylisoquinolin-2-ium
  • MW: 324.351 | Formula: C19H18NO4+
  • H donors: 0 H acceptors: 0 LogP: 3.65 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2cc(c3ccc4c(c3)OCO4)[n+](cc2cc1OC)C
  • InChi: 1S/C19H18NO4/c1-20-10-14-9-18(22-3)17(21-2)8-13(14)6-15(20)12-4-5-16-19(7-12)24-11-23-16/h4-10H,11H2,1-3H3/q+1
  • InChiKey: LDBUGRMRPMPDIN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-2-methyl-isoquinolin-2-ium

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) RecQ helicase 0.0023 0.0149 0.025
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0046 0.0051
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0192 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.029 0.0436
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.001 0.0008 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0192 0.0295
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0098 0.0164
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0008 0.0012
Brugia malayi bHLH-PAS transcription factor 0.004 0.0323 0.0541
Echinococcus granulosus single minded 2 0.004 0.0323 0.0541
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0014 0.0046 0.0077
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0473 0.0792
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0427 0.0668
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.029 0.0486
Echinococcus multilocularis aryl hydrocarbon receptor 0.0014 0.0046 0.0045
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0093 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0108 0.0107
Brugia malayi hypothetical protein 0.001 0.0008 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0108 0.018
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0262 0.0389
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0132 0.1313 0.2142
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0552 0.0925
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0089 0.0038
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Toxoplasma gondii thioredoxin reductase 0.0052 0.0454 0.076
Brugia malayi Dihydrofolate reductase 0.0132 0.1313 0.2202
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0108 0.018
Schistosoma mansoni hypothetical protein 0.0017 0.0079 0.0132
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.001 0.0008 0.0013
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0552 0.0925
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0281 0.2925 0.4905
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0089 0.0123
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0262 0.0331
Brugia malayi Pre-SET motif family protein 0.0066 0.0602 0.1009
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0089 0.0038
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0093 0.013
Schistosoma mansoni hypothetical protein 0.0017 0.0079 0.0132
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0014 0.0046 0.0025
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0108 0.0107
Trichomonas vaginalis hypothetical protein 0.0073 0.0677 0.1089
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.001 0.0008 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0108 0.018
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0247 0.0415
Plasmodium vivax glutathione reductase, putative 0.0052 0.0454 0.0655
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0108 0.018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0008 0.0012
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0031 0.0026
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0093 0.0156
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0108 0.0181
Brugia malayi Pre-SET motif family protein 0.0457 0.4816 0.8077
Echinococcus multilocularis dihydrofolate reductase 0.0132 0.1313 0.1313
Echinococcus multilocularis musashi 0.0061 0.0552 0.0551
Onchocerca volvulus 0.0054 0.0482 0.0801
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0089 0.0089
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0063 0.0576 0.0965
Loa Loa (eye worm) hypothetical protein 0.0066 0.0602 0.1009
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0031 0.0026
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0262 0.0389
Schistosoma mansoni single-minded 0.0054 0.0473 0.0792
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0046 0.0051
Brugia malayi isocitrate dehydrogenase 0.0018 0.0093 0.0155
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0192 0.032
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0066 0.0602 0.1009
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0008 0.0012
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0427 0.0716
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0469 0.0738
Loa Loa (eye worm) adenosylhomocysteinase 0.0563 0.5962 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0108 0.018
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0149 0.0199
Schistosoma mansoni adenosylhomocysteinase 0.0349 0.365 0.6122
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0149 0.0199
Leishmania major S-adenosylhomocysteine hydrolase 0.0563 0.5962 1
Trypanosoma brucei trypanothione reductase 0.0052 0.0454 0.0736
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0563 0.5962 1
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0014 0.0046 0.0076
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0089 0.0149
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Onchocerca volvulus 0.0027 0.0192 0.0267
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0213 0.0212
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0108 0.018
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0089 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0262 0.0389
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0261 0.2703 0.4472
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.001 0.0008 0.0012
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0454 0.062
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0132 0.1313 0.2084
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0105 0.0026
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0383 0.0641
Echinococcus granulosus dihydrofolate reductase 0.0132 0.1313 0.2202
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0552 0.0925
Brugia malayi nuclear receptor RXR 0.001 0.0008 0.0012
Echinococcus granulosus aryl hydrocarbon receptor 0.0014 0.0046 0.0076
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0046 0.0025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0089 0.0123
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0323 0.0322
Plasmodium falciparum thioredoxin reductase 0.0052 0.0454 0.076
Schistosoma mansoni intermediate filament proteins 0.0061 0.0552 0.0925
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0482 0.0808
Brugia malayi TAR-binding protein 0.0073 0.0685 0.1149
Brugia malayi RNA binding protein 0.0073 0.0685 0.1149
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0261 0.2703 0.4533
Loa Loa (eye worm) hypothetical protein 0.018 0.183 0.307
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Schistosoma mansoni hypothetical protein 0.0017 0.0079 0.0132
Plasmodium falciparum adenosylhomocysteinase 0.0563 0.5962 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0118 0.1168 0.1836
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0108 0.0107
Schistosoma mansoni adenosylhomocysteinase 0.0563 0.5962 1
Brugia malayi ecdysteroid receptor 0.002 0.0108 0.018
Onchocerca volvulus 0.0061 0.0552 0.0928
Mycobacterium ulcerans putative regulatory protein 0.004 0.0323 0.0475
Leishmania major protein kinase, putative 0.0014 0.0046 0.0051
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0093 0.013
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0093 0.0155
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0093 0.0044
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0093 0.0155
Loa Loa (eye worm) thymidylate synthase 0.0129 0.1286 0.2157
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0685 0.1149
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0563 0.5962 1
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0261 0.2703 0.4519
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Schistosoma mansoni rotamase 0.0037 0.029 0.0485
Brugia malayi steroid hormone receptor 0.002 0.0108 0.018
Echinococcus multilocularis GPCR, family 2 0.0017 0.0079 0.0079
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0089 0.2321
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0046 0.0025
Echinococcus granulosus tar DNA binding protein 0.0073 0.0685 0.1149
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0262 0.0389
Mycobacterium tuberculosis Conserved hypothetical protein 0.0126 0.125 0.1977
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0192 0.0295
Brugia malayi acetyltransferase, GNAT family protein 0.0168 0.1702 0.2854
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0079 0.0132
Loa Loa (eye worm) hypothetical protein 0.0027 0.0192 0.0321
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0192 0.032
Loa Loa (eye worm) phosphofructokinase 0.0126 0.1251 0.2097
Echinococcus granulosus histone lysine methyltransferase setb 0.0066 0.0602 0.1009
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0108 0.018
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0118 0.1168 0.1836
Mycobacterium tuberculosis Probable dehydrogenase 0.0118 0.1168 0.1836
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0563 0.5962 1
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.1251 0.2056
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0126 0.1251 0.1977
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0079 0.0132
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0132 0.1313 0.2147
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0281 0.2925 0.2925
Brugia malayi intermediate filament protein 0.0061 0.0552 0.0925
Leishmania major trypanothione reductase 0.0052 0.0454 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0108 0.018
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0042 0.0044
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0079 0.0132
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0108 0.018
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0262 0.0439
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0016 0.0026
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0168 0.1702 0.1702
Brugia malayi nuclear hormone receptor 0.002 0.0108 0.018
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0118 0.1168 0.1836
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0427 0.0611
Loa Loa (eye worm) hypothetical protein 0.0061 0.0552 0.0925
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0262 0.0389
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0066 0.0602 0.0601
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0557 0.0887
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0046 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0105 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0108 0.018
Onchocerca volvulus 0.052 0.5496 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.1251 0.2097
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0281 0.042
Onchocerca volvulus 0.002 0.0108 0.0113
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0108 0.0181
Schistosoma mansoni adenosylhomocysteinase 0.0349 0.365 0.6122
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0108 0.018
Echinococcus multilocularis 6 phosphofructokinase 0.0126 0.1251 0.125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0108 0.018
Trichomonas vaginalis rotamase, putative 0.0036 0.0281 0.042
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0108 0.018
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0089 0.0123
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0192 0.0295
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0108 0.018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0079 0.0133
Loa Loa (eye worm) hypothetical protein 0.0054 0.0474 0.0795
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0685 0.0685
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0177 0.18 0.2983
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0093 0.0155
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0261 0.2703 0.4519
Loa Loa (eye worm) RNA binding protein 0.0073 0.0685 0.115
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0454 0.0453
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1251 0.2056
Mycobacterium ulcerans 6-phosphofructokinase 0.0126 0.1251 0.2041
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0192 0.0253
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0093 0.0092
Brugia malayi hypothetical protein 0.0061 0.0557 0.0934
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0096 0.016
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0685 0.115
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0192 0.0253
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0196
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0089 0.008
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0563 0.5962 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0089 0.0123
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0042 0.007
Echinococcus granulosus 6 phosphofructokinase 0.0126 0.1251 0.2097
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0129 0.1286 0.2096
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0108 0.0107
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0046 0.0051
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0281 0.047
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0108 0.0113
Mycobacterium tuberculosis Hypothetical protein 0.0061 0.0557 0.0797
Chlamydia trachomatis dihydrofolate reductase 0.0132 0.1313 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0089 0.0149
Echinococcus granulosus thymidylate synthase 0.0129 0.1286 0.2156
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0325 0.3396 0.5672
Brugia malayi Cytochrome P450 family protein 0.0014 0.0042 0.0069
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0563 0.5962 1
Echinococcus multilocularis tumor protein p63 0.0372 0.3901 0.39
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0108 0.0107
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0427 0.0716
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0066 0.0602 0.0601
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0685 0.1149
Echinococcus granulosus lamin 0.0061 0.0552 0.0925
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0108 0.018
Echinococcus granulosus tumor protein p63 0.0372 0.3901 0.6542
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0192 0.0253
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0089 0.0123
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0281 0.0445
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0427 0.0668
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0105 0.0026
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0126 0.1251 1
Mycobacterium tuberculosis Probable reductase 0.0118 0.1168 0.1836
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0089 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0262 0.0439
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0108 0.018
Brugia malayi hypothetical protein 0.018 0.183 0.3069
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0046 0.0025
Echinococcus granulosus bloom syndrome protein 0.0023 0.0149 0.0249
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.1251 0.2097
Brugia malayi phosphofructokinase 0.0126 0.1251 0.2097
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0454 0.0736
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0108 0.0107
Schistosoma mansoni hypothetical protein 0.0017 0.0079 0.0132
Schistosoma mansoni nuclear hormone receptor 0.002 0.0108 0.018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0038 0.0063
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0563 0.5962 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0108 0.0181
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0383 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0474 0.0795
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0046 0.0051
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0089 0.0123
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0247 0.0414
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0118 0.1168 0.1896
Loa Loa (eye worm) hypothetical protein 0.0037 0.0291 0.0489
Mycobacterium ulcerans 2-dehydropantoate 2-reductase 0.0126 0.125 0.2041
Schistosoma mansoni adenosylhomocysteinase 0.0349 0.365 0.6122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0192 0.0321
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0108 0.0107
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0474 0.0795
Trichomonas vaginalis set domain proteins, putative 0.052 0.5496 0.9213
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0089 0.0123
Brugia malayi 6-phosphofructokinase 0.0126 0.1251 0.2097
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0383 0.0593
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0108 0.0107
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0262 0.6838
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0261 0.2703 0.4533
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0192 0.027
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0108 0.018
Mycobacterium tuberculosis Probable oxidoreductase 0.0131 0.1309 0.2078
Plasmodium falciparum glutathione reductase 0.0052 0.0454 0.076
Schistosoma mansoni thyroid hormone receptor 0.002 0.0108 0.018
Brugia malayi Thioredoxin reductase 0.0052 0.0454 0.076
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0192 0.027
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0129 0.1286 0.2038
Onchocerca volvulus 0.0061 0.0552 0.0928
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0108 0.0113
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0089 0.008
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0196
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0196
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0457 0.4816 0.8077
Echinococcus granulosus adenosylhomocysteinase 0.0563 0.5962 1
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0192 0.032
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0262 0.1488
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0108 0.018
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.1251 0.2056
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0262 0.0389
Brugia malayi dihydrofolate reductase family protein 0.0132 0.1313 0.2202
Schistosoma mansoni thyroid hormone receptor 0.002 0.0108 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0108 0.0181
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0079 0.0132
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0093 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0066 0.0602 0.1009
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0061 0.0557 0.0911
Loa Loa (eye worm) hypothetical protein 0.0028 0.0201 0.0336
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0427 0.0716
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0685 0.115
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0108 0.018
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0093 0.0155
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0563 0.5962 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0108 0.018
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.1251 0.2056
Echinococcus granulosus histone acetyltransferase KAT2B 0.0163 0.1651 0.2769
Loa Loa (eye worm) hypothetical protein 0.006 0.054 0.0905
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0089 0.0098
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0046 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0108 0.018
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.1251 0.2076
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0281 0.0445
Loa Loa (eye worm) acetyltransferase 0.0168 0.1702 0.2855
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0563 0.5962 1
Schistosoma mansoni coup transcription factor 0.002 0.0108 0.018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0213 0.0357
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0118 0.1168 0.1836
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0454 0.076
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0685 0.1149
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0117 0.0127
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0196
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0685 0.1149
Loa Loa (eye worm) dihydrofolate reductase 0.0132 0.1313 0.2202
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0042 0.0044
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.1251 0.2097
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.1251 0.2076
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0108 0.018
Brugia malayi 6-phosphofructokinase 0.0126 0.1251 0.2097
Echinococcus granulosus lamin dm0 0.0061 0.0552 0.0925
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0108 0.018
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0192 0.0253
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0563 0.5962 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0131 0.1309 0.2078
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0262 0.0439
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0108 0.018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0108 0.018
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0129 0.1286 0.2156
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0093 0.0092
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0093 0.013
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0001 0.0001
Brugia malayi nuclear receptor NHR-88 0.002 0.0108 0.018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0089 0.0123
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0563 0.5962 1
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0093 0.0155
Loa Loa (eye worm) hypothetical protein 0.0028 0.0201 0.0336
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1251 0.2056
Plasmodium falciparum glutathione reductase 0.0018 0.0089 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0108 0.0181
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0089 0.0098
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0192 0.0174
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0093 0.013
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0031 0.0026
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0089 0.0149
Onchocerca volvulus 0.0129 0.1286 0.2276
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0192 0.0253
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0042 0.007
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0117 0.0047
Brugia malayi glutathione reductase 0.0052 0.0454 0.076
Brugia malayi hypothetical protein 0.001 0.0008 0.0012
Mycobacterium ulcerans hypothetical protein 0.0027 0.0192 0.0253
Onchocerca volvulus 0.0066 0.0602 0.102
Toxoplasma gondii adenosylhomocysteinase, putative 0.0563 0.5962 1
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0046 0.0051
Toxoplasma gondii 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.0325 0.3396 0.5695
Echinococcus granulosus FTZ F1 alpha 0.002 0.0108 0.018
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0454 0.0655
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0281 0.2925 0.4905
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0108 0.0181
Echinococcus granulosus expressed protein 0.0037 0.029 0.0485
Brugia malayi Cytochrome P450 family protein 0.0014 0.0042 0.0069
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0262 0.0389
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0602 0.1009
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0025
Mycobacterium ulcerans thymidylate synthase 0.0129 0.1286 0.2102
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.1251 0.2097
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0262 0.0389
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0213 0.0356
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0108 0.018
Echinococcus multilocularis lamin dm0 0.0061 0.0552 0.0551
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0079 0.0133
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0105 0.0026
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0131 0.1309 0.2136
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0192 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0108 0.018
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0046 0.0051
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0046 0.0025
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0117 0.0195
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.029 0.0485
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0474 0.0795
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0108 0.018
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0042 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0108 0.0181
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0192 0.0174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0602 0.1009
Echinococcus multilocularis expressed protein 0.0037 0.029 0.0289
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0065 0.0108
Schistosoma mansoni adenosylhomocysteinase 0.0349 0.365 0.6122
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0192 0.0253
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1251 0.2056
Schistosoma mansoni lamin 0.0061 0.0552 0.0925
Loa Loa (eye worm) hypothetical protein 0.002 0.0108 0.0181
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0108 0.0107
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.000000000079747
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0192 0.0253
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0018 0.0089 0.0342
Leishmania major ATP-dependent phosphofructokinase 0.0126 0.1251 0.2076
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0025
Schistosoma mansoni dihydrofolate reductase 0.0132 0.1313 0.2202
Schistosoma mansoni hypothetical protein 0.0037 0.0291 0.0488
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0126 0.1251 0.2036
Loa Loa (eye worm) hypothetical protein 0.0054 0.0482 0.0809
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0602 0.1009
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0261 0.2703 0.4519
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0042 0.0044
Brugia malayi PAS domain containing protein 0.0054 0.0473 0.0792
Loa Loa (eye worm) hypothetical protein 0.002 0.0117 0.0196
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0108 0.018
Mycobacterium ulcerans ketopantoate reductase, ApbA 0.0325 0.3396 0.5664
Loa Loa (eye worm) glutathione reductase 0.0052 0.0454 0.0761
Schistosoma mansoni lamin 0.0061 0.0552 0.0925
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0089 0.0149
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0089 0.0149
Leishmania major protein kinase, putative 0.0014 0.0046 0.0051
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0089 0.0123
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0093 0.0092
Echinococcus granulosus intermediate filament protein 0.0061 0.0552 0.0925
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0046 0.0025
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0089 0.0123
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0108 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0108 0.0181
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0262 0.0439
Brugia malayi hypoxia-induced factor 1 0.0166 0.1681 0.2818
Echinococcus multilocularis lamin 0.0061 0.0552 0.0551
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0093 0.0092
Loa Loa (eye worm) hypoxia-induced factor 1 0.0166 0.1681 0.2819
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0281 0.0445
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0131 0.1309 0.2078
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0108 0.018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0192 0.0321
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.1251 0.2056
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0685 0.1149
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0149 0.0149
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0046 0.0051
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0454 0.0761
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0118 0.0198
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0108 0.018
Onchocerca volvulus 0.004 0.0323 0.0508
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0291 0.0488
Brugia malayi Adenosylhomocysteinase 0.0563 0.5962 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0108 0.018
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0281 0.0445
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0168 0.1702 0.2854
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0117 0.0084
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0089 0.0149
Echinococcus granulosus GPCR family 2 0.0017 0.0079 0.0132
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0108 0.0113
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0014 0.0046 0.0045
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0089 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0038 0.0063
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0149 0.0249
Plasmodium vivax SET domain protein, putative 0.0066 0.0602 0.0907
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0079 0.0079
Entamoeba histolytica adenosylhomocysteinase, putative 0.0563 0.5962 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0262 0.1705
Trichomonas vaginalis rotamase, putative 0.0037 0.029 0.0436
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0262 0.1705
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0093 0.0092
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0262 0.0439
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0192 0.027
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0089 0.0149
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0046 0.0025
Leishmania major cytochrome p450-like protein 0.0014 0.0042 0.0044
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0685 0.1149
Brugia malayi thymidylate synthase 0.0129 0.1286 0.2156
Echinococcus multilocularis thymidylate synthase 0.0129 0.1286 0.1286
Plasmodium falciparum thioredoxin reductase 0.0018 0.0089 0.0149
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Echinococcus multilocularis adenosylhomocysteinase 0.0563 0.5962 0.5962
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0093 0.013
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0262 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0325 0.3396 0.5672
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0117 0.0559

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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