Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | GPCR family 2 | 0.0035 | 0.0057 | 0.0072 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0327 | 0.1052 | 0.1418 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0055 | 0.0126 | 0.1433 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0299 | 0.0958 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.0421 | 0.4373 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0282 | 0.3259 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.003 | 0.0039 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.2193 | 0.7414 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0282 | 0.3259 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.003 | 0.0039 | 0.0418 |
Echinococcus granulosus | acetylcholinesterase | 0.0265 | 0.0841 | 0.113 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0004 | 0.0004 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.003 | 0.0039 | 0.4181 |
Loa Loa (eye worm) | carboxylesterase | 0.0265 | 0.0841 | 0.9798 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.003 | 0.0039 | 0.0036 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0101 | 0.0282 | 0.0244 |
Echinococcus granulosus | neuropeptide s receptor | 0.0507 | 0.1665 | 0.2242 |
Echinococcus granulosus | cpg binding protein | 0.0163 | 0.0493 | 0.0661 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Brugia malayi | AMP-binding enzyme family protein | 0.003 | 0.0039 | 0.0418 |
Leishmania major | acetyl-CoA synthetase, putative | 0.003 | 0.0039 | 0.0375 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.003 | 0.0039 | 0.0036 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.003 | 0.0039 | 0.0053 |
Mycobacterium ulcerans | hypothetical protein | 0.0541 | 0.1783 | 0.1783 |
Mycobacterium ulcerans | hypothetical protein | 0.0158 | 0.0475 | 0.0475 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0004 | 0.0004 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.003 | 0.0039 | 0.0036 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0265 | 0.0841 | 0.9798 |
Echinococcus multilocularis | cpg binding protein | 0.0163 | 0.0493 | 0.0548 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.003 | 0.0039 | 0.0375 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0035 | 0.0057 | 0.0626 |
Echinococcus multilocularis | dnaJ subfamily B | 0.2193 | 0.7414 | 0.8297 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0082 | 0.0819 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0079 | 0.0084 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1444 | 0.486 | 0.6555 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0043 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.0858 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0004 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.003 | 0.0039 | 0.0418 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0043 | 0.0054 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0038 | 0.0069 | 0.0088 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0045 | 0.0091 | 0.0118 |
Onchocerca volvulus | 0.0031 | 0.0043 | 0.0094 | |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.003 | 0.0039 | 0.0375 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0181 | 0.0178 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0043 | 0.0045 |
Echinococcus multilocularis | GPCR, family 2 | 0.0035 | 0.0057 | 0.006 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.0091 | 0.0087 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0024 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0195 | 0.2242 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.011 | 0.0313 | 0.3624 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0074 | 0.0099 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU | 0.2952 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0043 | 0.0054 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0101 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0043 | 0.0465 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.0091 | 0.0087 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0043 | 0.0465 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0541 | 0.1783 | 0.178 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.003 | 0.0039 | 0.2 |
Onchocerca volvulus | 0.0045 | 0.0091 | 0.1217 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.0175 | 0.0192 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0113 | 0.1148 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0075 | 0.0195 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0313 | 0.3624 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0117 | 0.0337 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0079 | 0.0878 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0091 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0043 | 0.0465 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0041 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0057 | 0.006 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0038 | 0.0069 | 0.0073 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0079 | 0.0878 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.003 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.0841 | 0.9798 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0057 | 0.0072 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0245 | 0.0271 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Onchocerca volvulus | 0.0045 | 0.0091 | 0.1217 | |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.0175 | 0.2006 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.003 | 0.0039 | 0.4181 |
Brugia malayi | AMP-binding enzyme family protein | 0.0101 | 0.0282 | 0.3259 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0195 | 0.2242 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0039 | 0.0418 |
Echinococcus granulosus | lamin | 0.0031 | 0.0043 | 0.0054 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.003 | 0.0039 | 0.0375 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.0175 | 0.2006 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0045 | 0.0091 | 0.0098 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.0265 | 0.306 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0181 | 0.0178 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.003 | 0.0039 | 0.0418 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.003 | 0.0039 | 0.0892 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0101 | 0.0282 | 0.0279 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.003 | 0.0039 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0195 | 0.0262 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0048 | 0.0101 | 0.0109 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0265 | 0.0841 | 0.1134 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0101 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.0337 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0048 | 0.0101 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.0501 | 0.0675 |
Schistosoma mansoni | lamin | 0.0031 | 0.0043 | 0.0058 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0038 | 0.0069 | 0.0092 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.027 | 0.0858 | 0.0957 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0079 | 0.0106 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0022 | 0.0014 | 0.0018 |
Schistosoma mansoni | cpg binding protein | 0.0163 | 0.0493 | 0.0665 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0075 | 0.0195 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0045 | 0.0091 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0074 | 0.0099 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1444 | 0.486 | 0.5437 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.003 | 0.0039 | 0.0375 |
Brugia malayi | AMP-binding enzyme family protein | 0.0101 | 0.0282 | 0.3259 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.0405 | 0.0542 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0082 | 0.0819 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.0337 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0039 | 0.0036 |
Loa Loa (eye worm) | histone methyltransferase | 0.0048 | 0.0101 | 0.1138 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.011 | 0.1247 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1444 | 0.486 | 0.6553 |
Brugia malayi | RNA binding protein | 0.0069 | 0.0175 | 0.2006 |
Toxoplasma gondii | eukaryotic initiation factor-2B, gamma subunit, putative | 0.0541 | 0.1783 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0074 | 0.0099 |
Onchocerca volvulus | 0.0055 | 0.0126 | 0.2045 | |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0025 | 0.0022 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0075 | 0.0195 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0265 | 0.0841 | 0.9798 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.027 | 0.0364 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0057 | 0.0072 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0043 | 0.0465 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0101 | 0.0282 | 0.8374 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0507 | 0.1665 | 0.2242 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0101 | 0.0282 | 0.0282 |
Echinococcus multilocularis | neuroligin | 0.0045 | 0.0091 | 0.0098 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0057 | 0.0076 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.025 | 0.079 | 0.9201 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0175 | 0.0236 |
Brugia malayi | Carboxylesterase family protein | 0.0265 | 0.0841 | 0.9798 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0158 | 0.0475 | 0.0472 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.003 | 0.0039 | 0.0036 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0045 | 0.0091 | 0.0098 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0142 | 0.0421 | 0.4373 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0045 | 0.0091 | 0.0091 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0035 | 0.0057 | 0.0626 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.003 | 0.0039 | 0.0418 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0101 | 0.0282 | 0.2919 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.2952 | 1 | 0.5 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.003 | 0.0039 | 0.0039 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0038 | 0.0069 | 0.0073 |
Treponema pallidum | licC protein (licC) | 0.0541 | 0.1783 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0265 | 0.0841 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0265 | 0.306 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0075 | 0.0195 | 0.0195 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0045 | 0.0091 | 0.0118 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0101 | 0.0282 | 0.0279 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.003 | 0.0039 | 0.0039 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0175 | 0.0236 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0541 | 0.1783 | 0.178 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0507 | 0.1665 | 0.1861 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0057 | 0.0626 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0045 | 0.0091 | 0.0122 |
Schistosoma mansoni | survival motor neuron protein | 0.0055 | 0.0126 | 0.0169 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0265 | 0.0841 | 0.0937 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0043 | 0.0045 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.0091 | 0.1022 |
Echinococcus granulosus | acetylcholinesterase | 0.0265 | 0.0841 | 0.113 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.0175 | 0.2006 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Onchocerca volvulus | 0.0154 | 0.0463 | 1 | |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.003 | 0.0039 | 0.0036 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0175 | 0.0236 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0181 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Schistosoma mansoni | gliotactin | 0.0045 | 0.0091 | 0.0122 |
Brugia malayi | CXXC zinc finger family protein | 0.0154 | 0.0463 | 0.538 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0024 | 0.0215 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0091 | 0.1022 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0082 | 0.0819 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0101 | 0.0282 | 0.8374 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0075 | 0.0195 | 0.2236 |
Schistosoma mansoni | cpg binding protein | 0.0163 | 0.0493 | 0.0665 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0079 | 0.861 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0024 | 0.0215 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0039 | 0.0036 |
Echinococcus multilocularis | geminin | 0.0165 | 0.0501 | 0.0556 |
Brugia malayi | AMP-binding enzyme family protein | 0.0101 | 0.0282 | 0.3259 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0024 | 0.024 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Toxoplasma gondii | propionate-CoA ligase | 0.003 | 0.0039 | 0.0087 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.011 | 0.0313 | 0.3624 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.003 | 0.0039 | 0.0375 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0039 | 0.0036 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0091 | 0.1022 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0024 | 0.0215 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.003 | 0.0039 | 0.0039 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0047 | 0.0099 | 0.1114 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0195 | 0.2242 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0024 | 0.1217 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.003 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.0841 | 0.9798 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.0337 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0101 | 0.0282 | 0.8374 |
Brugia malayi | hypothetical protein | 0.027 | 0.0858 | 1 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0024 | 0.024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.0501 | 0.0675 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.0175 | 0.2006 |
Onchocerca volvulus | 0.0045 | 0.0091 | 0.1217 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0091 | 0.0122 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0004 | 0.0095 |
Onchocerca volvulus | 0.0031 | 0.0043 | 0.0094 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0292 | 0.0933 | 0.5166 |
Echinococcus granulosus | dnaJ subfamily B | 0.2193 | 0.7414 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0091 | 0.1022 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0181 | 0.0178 |
Echinococcus multilocularis | acetylcholinesterase | 0.0265 | 0.0841 | 0.0937 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0101 | 0.0282 | 0.0244 |
Mycobacterium ulcerans | hypothetical protein | 0.0541 | 0.1783 | 0.1783 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0299 | 0.0958 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.003 | 0.0039 | 0.0375 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0079 | 0.0878 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0079 | 0.0101 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0101 | 0.0282 | 0.2919 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0004 | 0.0004 |
Schistosoma mansoni | cpg binding protein | 0.0154 | 0.0463 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0091 | 0.1022 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0082 | 0.0819 |
Loa Loa (eye worm) | oxidoreductase | 0.003 | 0.0039 | 0.0418 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0079 | 0.0101 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0079 | 0.0084 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.0175 | 0.0231 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0074 | 0.0099 |
Mycobacterium ulcerans | molybdopterin-guanine dinucleotide biosynthesis protein A | 0.0541 | 0.1783 | 0.1783 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.0337 | 0.0454 |
Schistosoma mansoni | acetylcholinesterase | 0.0045 | 0.0091 | 0.0122 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0091 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0195 | 0.2242 |
Echinococcus granulosus | geminin | 0.0165 | 0.0501 | 0.0671 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0101 | 0.0282 | 0.2919 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.003 | 0.0039 | 0.0036 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0154 | 0.0463 | 0.538 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0195 | 0.2236 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0043 | 0.0465 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.011 | 0.0313 | 0.3624 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0045 | 0.0091 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.003 | 0.0039 | 0.0039 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.003 | 0.0039 | 0.0087 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.0175 | 0.2006 |
Brugia malayi | hypothetical protein | 0.0117 | 0.0337 | 0.3899 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0507 | 0.1665 | 0.1861 |
Onchocerca volvulus | 0.0045 | 0.0091 | 0.1217 | |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0245 | 0.0326 |
Onchocerca volvulus | 0.0045 | 0.0091 | 0.1217 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0117 | 0.0337 | 0.0454 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0038 | 0.0069 | 0.0088 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0175 | 0.0236 |
Brugia malayi | MH2 domain containing protein | 0.025 | 0.079 | 0.9201 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.003 | 0.0039 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0126 | 0.0169 |
Schistosoma mansoni | lamin | 0.0031 | 0.0043 | 0.0058 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0075 | 0.0195 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.003 | 0.0039 | 0.0418 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0282 | 0.3259 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0117 | 0.0337 | 0.045 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0101 | 0.0282 | 0.0282 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0101 | 0.0282 | 0.0282 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0045 | 0.0091 | 0.0118 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.0265 | 0.0293 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0045 | 0.0091 | 0.0122 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.0265 | 0.7868 |
Leishmania major | acetyl-CoA synthetase, putative | 0.003 | 0.0039 | 0.0375 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.0421 | 0.4373 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0101 | 0.0282 | 0.0282 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.027 | 0.0858 | 0.1153 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0098 | 0.0106 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0057 | 0.0076 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.264 | 0.8936 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0045 | 0.0091 | 0.0098 |
Trichomonas vaginalis | helicase, putative | 0.0035 | 0.0057 | 0.6216 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0024 | 0.1217 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0057 | 0.0076 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0057 | 0.0076 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0175 | 0.0236 |
Brugia malayi | AMP-binding enzyme family protein | 0.003 | 0.0039 | 0.0418 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.003 | 0.0039 | 0.0418 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.0282 | 0.0282 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0004 | 0.0149 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0057 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0195 | 0.2242 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.003 | 0.0039 | 0.0036 |
Entamoeba histolytica | hypothetical protein | 0.0117 | 0.0337 | 1 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.003 | 0.0039 | 0.004 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Onchocerca volvulus | 0.0101 | 0.0282 | 0.5724 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.003 | 0.0039 | 0.0048 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.003 | 0.0039 | 0.0087 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0101 | 0.0282 | 0.0282 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0103 | 0.0448 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0004 | 0.0004 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0004 | 0.0149 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0299 | 0.0958 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0265 | 0.0841 | 0.113 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.0265 | 0.0353 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0299 | 0.0958 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.0091 | 0.1022 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0035 | 0.0057 | 0.0626 |
Echinococcus granulosus | neuroligin | 0.0045 | 0.0091 | 0.0118 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0057 | 0.6216 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.0405 | 0.045 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0043 | 0.0058 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.003 | 0.0039 | 0.1158 |
Mycobacterium ulcerans | bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase | 0.2952 | 1 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0035 | 0.0057 | 0.6216 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0091 | 0.1022 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.025 | 0.079 | 0.9201 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.003 | 0.0039 | 0.0375 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0045 | 0.0091 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0039 | 0.0418 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.