Detailed information for compound 1171735

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 573.639 | Formula: C31H35N5O6
  • H donors: 1 H acceptors: 4 LogP: 2.2 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: CO/N=C\1/C(=O)N(c2c1cccc2)CCN(C1CCCN(C1)c1ccc2c(c1OC)n(cc(c2=O)C(=O)O)C1CC1)C
  • InChi: 1S/C31H35N5O6/c1-33(15-16-35-24-9-5-4-8-21(24)26(30(35)38)32-42-3)20-7-6-14-34(17-20)25-13-12-22-27(29(25)41-2)36(19-10-11-19)18-23(28(22)37)31(39)40/h4-5,8-9,12-13,18-20H,6-7,10-11,14-17H2,1-3H3,(H,39,40)/b32-26+
  • InChiKey: FZBPCNUFGBSWBC-HMZBKAONSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis endoplasmin 0.0026 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Loa Loa (eye worm) endoplasmin 0.0032 0.0064 0.024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0183 0.0331
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0068 0.0943
Brugia malayi CHE-14 protein 0.0047 0.0119 0.0446
Loa Loa (eye worm) steroid hormone receptor 0.0063 0.0183 0.0683
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0045 0.0281
Brugia malayi hypothetical protein 0.044 0.1635 0.6109
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0063 0.0183 0.0331
Mycobacterium ulcerans hypothetical protein 0.0026 0.0041 0.0541
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0063 0.0183 0.0331
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.1068
Schistosoma mansoni cpg binding protein 0.0121 0.0406 0.0737
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0172 0.0601 0.827
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0204 0.0726 0.2714
Treponema pallidum fructose-bisphosphate aldolase 0.029 0.1058 1
Echinococcus granulosus cpg binding protein 0.0128 0.0433 0.0785
Echinococcus granulosus tumor protein p63 0.0373 0.1375 0.2495
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0063 0.0183 0.0683
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0064 0.078
Brugia malayi ecdysteroid receptor 0.0063 0.0183 0.0683
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0054 0.0203
Onchocerca volvulus 0.0053 0.0145 0.0654
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0085 0.0661
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0045 0.0281
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0091 0.125
Echinococcus multilocularis cyclin dependent kinase 1 0.0172 0.0601 0.0601
Schistosoma mansoni cpg binding protein 0.0128 0.0433 0.0785
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.0365 0.0661
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0078 0.0866
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0084 0.0084
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0085 0.0661
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0601 0.109
Mycobacterium ulcerans beta-lactamase 0.0036 0.0078 0.1327
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0255
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0236 0.0428
Schistosoma mansoni lozenge 0.0055 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Loa Loa (eye worm) ICD-1 protein 0.0039 0.0091 0.0339
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0117 0.0213
Schistosoma mansoni nuclear receptor 0.003 0.0054 0.0099
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0085 0.0085
Echinococcus multilocularis cyclin dependent kinase 5 0.0172 0.0601 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0041 0.0366
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0078 0.1291
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0172 0.0601 0.109
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0039 0.007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0119 0.0446
Echinococcus granulosus heat shock protein 90 0.0032 0.0064 0.0116
Echinococcus multilocularis cyclin dependent kinase 1 0.0172 0.0601 0.0601
Echinococcus granulosus dnaJ subfamily B 0.1316 0.5009 0.9088
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0068 0.0124
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0172 0.0601 0.2245
Trypanosoma cruzi cdc2-related kinase 1 0.0172 0.0601 0.827
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0084 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0063 0.0183 0.0683
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0078 0.059
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0054 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0183 0.0683
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0064 0.0232
Leishmania major basic transcription factor 3a, putative 0.0039 0.0091 0.125
Onchocerca volvulus Huntingtin homolog 0.0122 0.0409 0.2309
Schistosoma mansoni hypothetical protein 0.0169 0.059 0.1071
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0117 0.0439
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0183 0.0683
Echinococcus granulosus neuropeptide s receptor 0.051 0.1904 0.3455
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0078 0.0141
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0041 0.0151
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0056
Schistosoma mansoni patched 1 0.0047 0.0119 0.0216
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.082 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0063 0.0183 0.0683
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0236 0.0236
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0041 0.0541
Echinococcus multilocularis transcription factor Dp 1 0.0118 0.0395 0.0395
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0119 0.0446
Echinococcus granulosus Niemann Pick C1 protein 0.0155 0.0538 0.0975
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0257 0.0929 0.1685
Brugia malayi heat shock protein 90 0.0032 0.0064 0.024
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0068 0.0832
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0255
Loa Loa (eye worm) runx1 0.0055 0.0152 0.057
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0068 0.0255
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0068 0.0711
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0041 0.0541
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0054 0.0054
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Mycobacterium tuberculosis Conserved protein 0.0036 0.0078 0.0823
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0056 0.0056
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0054 0.0099
Echinococcus multilocularis transcription factor btf3 0.0039 0.0091 0.0091
Echinococcus multilocularis neuropeptide receptor A26 0.051 0.1904 0.1904
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0041 0.0558
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.1058 1
Schistosoma mansoni endoplasmin 0.0032 0.0064 0.0116
Brugia malayi nuclear hormone receptor 0.0063 0.0183 0.0683
Echinococcus granulosus transcription factor btf3 0.0039 0.0091 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0091 0.0717
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0204 0.0726 1
Echinococcus granulosus heat shock protein 90 0.0026 0.0039 0.007
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.0944 0.1713
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0078 0.0141
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0204 0.0726 0.6738
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0192 0.0349
Schistosoma mansoni nuclear receptor 0.003 0.0054 0.0099
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0486 0.5873
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0068 0.0124
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0172 0.0601 0.2245
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0041 0.0366
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.1068
Schistosoma mansoni hypothetical protein 0.0045 0.0113 0.0205
Brugia malayi conserved hypotetical protein 0.003 0.0054 0.0203
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0204 0.0726 1
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.0091 0.1512
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0054 0.0203
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0192 0.0718
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0054 0.0203
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0486 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0192 0.0349
Trypanosoma brucei cdc2-related kinase 3 0.0172 0.0601 0.827
Echinococcus multilocularis neuropeptide s receptor 0.051 0.1904 0.1904
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0078 0.0823
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0054 0.0203
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0064 0.0461
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0078 0.059
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0064 0.0883
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0053 0.0145 0.0263
Loa Loa (eye worm) DR-78 0.003 0.0054 0.0203
Mycobacterium leprae Probable lipase LipE 0.0036 0.0078 0.0866
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.015 0.0272
Brugia malayi Nuclear hormone receptor E75 0.003 0.0054 0.0203
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0015 0.5
Mycobacterium ulcerans hypothetical protein 0.0036 0.0078 0.1327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0045 0.0281
Echinococcus multilocularis heat shock protein 0.0032 0.0064 0.0064
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0084 0.0314
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0183 0.0331
Onchocerca volvulus 0.003 0.0054 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.071 0.2676 0.4854
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0078 0.1068
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0068 0.0068
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.0151
Brugia malayi nuclear receptor NHR-67 0.003 0.0054 0.0203
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0068 0.0124
Brugia malayi ecdysone receptor 0.003 0.0054 0.0203
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0045 0.0281
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0183 0.0331
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.0091 0.0494
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0358 0.065
Echinococcus granulosus endoplasmin 0.0026 0.0039 0.007
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Echinococcus multilocularis dnaJ subfamily B 0.1316 0.5009 0.5009
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0085 0.117
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0172 0.0601 0.827
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0039 0.0535
Entamoeba histolytica hypothetical protein 0.0077 0.0236 0.1922
Echinococcus multilocularis FTZ F1 alpha 0.0063 0.0183 0.0183
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0063 0.0183 0.0331
Onchocerca volvulus 0.003 0.0054 0.0087
Plasmodium falciparum endoplasmin, putative 0.002 0.0016 0.0268
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0166 0.0166
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0063 0.0183 0.0331
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0117 0.0439
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.029
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0078 0.0823
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0054 0.0203
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0054 0.0099
Schistosoma mansoni hypothetical protein 0.0077 0.0236 0.0428
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.071 0.2676 0.2676
Schistosoma mansoni heat shock protein 0.0032 0.0064 0.0116
Schistosoma mansoni transcription factor btf3 0.0039 0.0091 0.0165
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Schistosoma mansoni nuclear hormone receptor 0.003 0.0054 0.0099
Onchocerca volvulus 0.0036 0.0078 0.0232
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0068 0.0068
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0358 0.1338
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0117 0.0213
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0039 0.0535
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0078 0.059
Echinococcus granulosus microtubule associated protein 2 0.1447 0.5512 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0063 0.0183 0.0183
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0054 0.0099
Brugia malayi hypothetical protein 0.0261 0.0944 0.3529
Plasmodium vivax endoplasmin, putative 0.0032 0.0064 0.1068
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0068 0.0943
Loa Loa (eye worm) hypothetical protein 0.044 0.1635 0.6109
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0041 0.0558
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0054 0.0203
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0063 0.0183 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0091 0.0717
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0117 0.0213
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0085 0.1415
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0039 0.0218
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0063 0.0183 0.0183
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0183 0.0183
Echinococcus granulosus transcription factor Dp 1 0.0118 0.0395 0.0717
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0056
Loa Loa (eye worm) hypothetical protein 0.0055 0.015 0.056
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0078 0.029
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0041 0.0541
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0056 0.0056
Entamoeba histolytica hypothetical protein 0.0039 0.0091 0.0494
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0078 0.0823
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0054 0.0099
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0063 0.0183 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0183 0.0683
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0068 0.114
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0119 0.0216
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0041 0.0151
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0068 0.0124
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0007 0.0012
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0068 0.0124
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0015 0.0251
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0045 0.0281
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Onchocerca volvulus Bile acid receptor homolog 0.0063 0.0183 0.0892
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0054 0.0054
Plasmodium falciparum heat shock protein 90 0.0032 0.0064 0.1068
Loa Loa (eye worm) hypothetical protein 0.0161 0.0561 0.2097
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0039 0.0345
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Brugia malayi hypothetical protein 0.0033 0.0068 0.0255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0063 0.0183 0.0683
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0041 0.0541
Onchocerca volvulus 0.0036 0.0078 0.0232
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0056
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0054 0.0054
Onchocerca volvulus Huntingtin homolog 0.0122 0.0409 0.2309
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0117 0.0117
Brugia malayi CXXC zinc finger family protein 0.0121 0.0406 0.1517
Echinococcus granulosus MAP kinase activated protein kinase 2 0.071 0.2676 0.4854
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0068 0.114
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0068 0.0832
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0119 0.0119
Echinococcus granulosus cyclin dependent kinase 0.0172 0.0601 0.109
Schistosoma mansoni heat shock protein 0.0032 0.0064 0.0116
Brugia malayi nuclear receptor RXR 0.003 0.0054 0.0203
Echinococcus granulosus FTZ F1 alpha 0.0063 0.0183 0.0331
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.0091 0.125
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0119 0.0216
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.029
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0085 0.117
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0056 0.0101
Mycobacterium tuberculosis Conserved protein 0.0036 0.0078 0.0823
Schistosoma mansoni endoplasmin 0.0032 0.0064 0.0116
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0054 0.0099
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.0409 0.1527
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.029
Echinococcus granulosus geminin 0.0169 0.059 0.1071
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0601 0.5609
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0204 0.0726 1
Onchocerca volvulus 0.0055 0.015 0.0686
Brugia malayi Steroid receptor seven-up type 2 0.0063 0.0183 0.0683
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0204 0.0726 0.1318
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0078 0.0078
Brugia malayi Protein kinase domain containing protein 0.0172 0.0601 0.2245
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0063 0.0183 0.0683
Schistosoma mansoni hypothetical protein 0.1316 0.5009 0.9088
Brugia malayi nuclear receptor NHR-88 0.0063 0.0183 0.0683
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0063 0.0183 0.0683
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0064 0.0883
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0056
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0078 0.0823
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Brugia malayi tailless protein 0.003 0.0054 0.0203
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0041 0.0541
Brugia malayi isocitrate dehydrogenase 0.0033 0.0068 0.0256
Onchocerca volvulus 0.0167 0.0582 0.3395
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0255
Toxoplasma gondii histone lysine methyltransferase SET1 0.0229 0.0823 1
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0064 0.024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.029
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0064 0.078
Echinococcus multilocularis cyclin dependent kinase 0.0172 0.0601 0.0601
Echinococcus multilocularis heat shock protein 90 0.0026 0.0039 0.0039
Brugia malayi beta-lactamase family protein 0.0036 0.0078 0.029
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0486 1
Brugia malayi jmjC domain containing protein 0.0059 0.0166 0.0619
Onchocerca volvulus 0.0036 0.0078 0.0232
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0064 0.0248
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0054 0.0087
Echinococcus granulosus heat shock protein 0.0032 0.0064 0.0116
Brugia malayi jmjC domain containing protein 0.0066 0.0192 0.0718
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0068 0.0943
Brugia malayi Endoplasmin precursor 0.0032 0.0064 0.024
Toxoplasma gondii exonuclease III APE 0.0038 0.0085 0.1033
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0068 0.0255
Giardia lamblia Kinase, CMGC CDK 0.0172 0.0601 0.5511
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.0091 0.1512
Trypanosoma cruzi cdc2-related kinase 1 0.0172 0.0601 0.827
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0117 0.0213
Brugia malayi hypothetical protein 0.003 0.0054 0.0203
Brugia malayi beta-lactamase family protein 0.0036 0.0078 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Brugia malayi steroid hormone receptor 0.0063 0.0183 0.0683
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0041 0.0151
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Echinococcus multilocularis Niemann Pick C1 protein 0.0155 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0054 0.0054
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0085 0.0318
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0117 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0063 0.0183 0.0683
Brugia malayi hypothetical protein 0.0077 0.0236 0.0883
Loa Loa (eye worm) hypothetical protein 0.0122 0.0409 0.1527
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0204 0.0726 0.0726
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.1058 1
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0039 0.0505
Schistosoma mansoni cpg binding protein 0.0128 0.0433 0.0785
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0204 0.0726 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0166 0.0166
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0063 0.0183 0.0331
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Loa Loa (eye worm) DEAH box polypeptide 35 0.0161 0.0561 0.2097
Onchocerca volvulus 0.0121 0.0406 0.2293
Mycobacterium ulcerans lipase LipD 0.0036 0.0078 0.1327
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0078 0.0141
Brugia malayi map kinase activated protein kinase protein 2 0.071 0.2676 1
Trichomonas vaginalis helicase, putative 0.0027 0.0045 0.0281
Entamoeba histolytica hypothetical protein 0.0077 0.0236 0.1922
Schistosoma mansoni retinoic acid receptor RXR 0.0063 0.0183 0.0331
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0068 0.0256
Loa Loa (eye worm) hypothetical protein 0.0109 0.0358 0.1338
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0082 0.0307
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0064 0.0883
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0183 0.0683
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0068 0.0068
Echinococcus multilocularis protein dispatched 1 0.0053 0.0145 0.0145
Onchocerca volvulus 0.044 0.1635 1
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0064 0.0883
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0068 0.0943
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Echinococcus multilocularis geminin 0.0169 0.059 0.059
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0068 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Schistosoma mansoni RAR-like nuclear receptor 0.0063 0.0183 0.0331
Mycobacterium tuberculosis Conserved protein 0.0036 0.0078 0.0823
Brugia malayi hypothetical protein 0.0167 0.0582 0.2174
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0039 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0063 0.0183 0.0683
Echinococcus granulosus neuropeptide receptor A26 0.051 0.1904 0.3455
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0192 0.0349
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0078 0.0823
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0068 0.0943
Brugia malayi Nuclear hormone receptor E75 0.003 0.0054 0.0203
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Schistosoma mansoni survival motor neuron protein 0.0053 0.0145 0.0263
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0015 0.0251
Loa Loa (eye worm) hypothetical protein 0.044 0.1635 0.6109
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0063 0.0183 0.0183
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0045 0.0281
Giardia lamblia Kinase, CMGC CDK 0.0172 0.0601 0.5511
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0063 0.0183 0.0331
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0085 0.117
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0085 0.117
Echinococcus multilocularis microtubule associated protein 2 0.1447 0.5512 0.5512
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Brugia malayi beta-lactamase 0.0036 0.0078 0.029
Trichomonas vaginalis esterase, putative 0.0036 0.0078 0.059
Schistosoma mansoni hypothetical protein 0.0045 0.0113 0.0205
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0078 0.1327
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0078 0.059
Leishmania major hypothetical protein, conserved 0.0036 0.0078 0.1068
Echinococcus multilocularis ecdysone induced protein 78C 0.0063 0.0183 0.0183
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0064 0.1068
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0117 0.0117
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0064 0.0883
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0166 0.03
Brugia malayi hypothetical protein 0.0122 0.0409 0.1527
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0056 0.0101
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0064 0.0232
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0054 0.0099
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Schistosoma mansoni ap endonuclease 0.0038 0.0085 0.0154
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0027 0.0027
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0078 0.059
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0054 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0063 0.0183 0.0683
Echinococcus granulosus cyclin dependent kinase 5 0.0172 0.0601 0.109
Onchocerca volvulus Protein ultraspiracle homolog 0.0063 0.0183 0.0892
Plasmodium falciparum protein kinase 5 0.0172 0.0601 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0183 0.0683
Echinococcus multilocularis cpg binding protein 0.0128 0.0433 0.0433
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0085 0.0154
Schistosoma mansoni ap endonuclease 0.0038 0.0085 0.0154
Schistosoma mansoni zinc finger protein 0.003 0.0054 0.0099
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0204 0.0726 0.1318
Brugia malayi beta-NAC-like protein 0.0039 0.0091 0.0339
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0056
Schistosoma mansoni coup transcription factor 0.0063 0.0183 0.0331
Plasmodium vivax protein kinase Crk2 0.0172 0.0601 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0063 0.0183 0.0683
Entamoeba histolytica hypothetical protein 0.0077 0.0236 0.1922
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0063 0.0183 0.0331
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0068 0.0256
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0601 0.5609
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0063 0.0183 0.0892
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0085 0.0318
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0204 0.0726 0.2714
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Loa Loa (eye worm) hypothetical protein 0.0063 0.0183 0.0683
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.0944 0.0944
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0085 0.0453
Entamoeba histolytica cell division protein kinase 2, putative 0.0172 0.0601 0.5504
Schistosoma mansoni hypothetical protein 0.0045 0.0113 0.0205
Trypanosoma cruzi cdc2-related kinase 3 0.0172 0.0601 0.827
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0054 0.0203
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0085 0.0437
Schistosoma mansoni microtubule-associated protein tau 0.1447 0.5512 1
Brugia malayi hypothetical protein 0.0033 0.0068 0.0255
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0064 0.0883
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0085 0.1415
Trypanosoma brucei heat shock protein, putative 0.0032 0.0064 0.0883
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0041 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0601 0.109
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0057 0.016 0.0597
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0054 0.0099
Echinococcus multilocularis heat shock protein 90 0.0032 0.0064 0.0064
Entamoeba histolytica hypothetical protein 0.0077 0.0236 0.1922
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0236 0.0428
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0045 0.0281
Giardia lamblia Fructose-bisphosphate aldolase 0.029 0.1058 1
Trypanosoma brucei cdc2-related kinase 1 0.0172 0.0601 0.827
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0045 0.0281
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0183 0.0331
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0172 0.0601 0.2245
Echinococcus granulosus expressed conserved protein 0.0102 0.0333 0.0604
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0041 0.0541
Echinococcus granulosus cyclin dependent kinase 1 0.0172 0.0601 0.109
Entamoeba histolytica cell division protein kinase 2, putative 0.0172 0.0601 0.5504
Schistosoma mansoni hypothetical protein 0.0169 0.059 0.1071
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0015 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0063 0.0183 0.0683
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0085 0.0915
Echinococcus multilocularis protein patched 0.0047 0.0119 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0063 0.0183 0.0683
Onchocerca volvulus 0.0063 0.0183 0.0892
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0085 0.1485
Echinococcus granulosus ecdysone induced protein 78C 0.0063 0.0183 0.0331
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.0151
Echinococcus multilocularis tumor protein p63 0.0373 0.1375 0.1375
Brugia malayi nuclear receptor RXR 0.0033 0.0068 0.0255
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0039 0.0535
Loa Loa (eye worm) hypothetical protein 0.0167 0.0582 0.2174
Brugia malayi cell division control protein 2 homolog 0.0172 0.0601 0.2245
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0085 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.029
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0027 0.0048
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0172 0.0601 0.7298
Loa Loa (eye worm) CXXC zinc finger family protein 0.0121 0.0406 0.1517
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0041 0.0038
Echinococcus multilocularis thyroid hormone receptor alpha 0.0063 0.0183 0.0183
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0056 0.0101
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.071 0.2676 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0054 0.0054
Echinococcus multilocularis Protein lozenge 0.0055 0.0152 0.0152
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0183 0.0183
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Loa Loa (eye worm) hypothetical protein 0.0261 0.0944 0.3529
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0183 0.0683
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0085 0.0453
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0041 0.0558
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0183 0.0683
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0063 0.0183 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0063 0.0183 0.0331
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0063 0.0183 0.0331
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Brugia malayi nuclear hormone receptor 0.003 0.0054 0.0203
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0091 0.125
Toxoplasma gondii ABC1 family protein 0.0036 0.0078 0.0942
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0063 0.0183 0.0683
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0091 0.0717
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0166 0.03
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0064 0.0883
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.099
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0045 0.0281
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0601 0.5609
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0358 0.0358
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0054 0.0099
Leishmania major heat shock protein 83-1 0.0032 0.0064 0.0883
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0078 0.0823
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0064 0.0883
Brugia malayi Probable ATP-dependent helicase DHX35 0.0161 0.0561 0.2097
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0255
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.0151
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0078 0.0823
Toxoplasma gondii NAC domain-containing protein 0.0039 0.0091 0.1103
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0039 0.0218
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0183 0.0331
Brugia malayi hypothetical protein 0.003 0.0054 0.0203
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0041 0.0541
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0013 0.0182
Schistosoma mansoni nuclear hormone receptor 0.003 0.0054 0.0099
Trypanosoma cruzi cdc2-related kinase 3 0.0172 0.0601 0.827
Echinococcus multilocularis expressed conserved protein 0.0102 0.0333 0.0333
Schistosoma mansoni hypothetical protein 0.0045 0.0113 0.0205
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0358 0.312
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0145 0.0541
Loa Loa (eye worm) hypothetical protein 0.0168 0.0587 0.2192
Schistosoma mansoni steroid hormone receptor ad4bp 0.0063 0.0183 0.0331
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0078 0.029
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0068 0.0255
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0078 0.1327
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0054 0.0099
Brugia malayi nuclear receptor NHR-88 0.003 0.0054 0.0203
Loa Loa (eye worm) beta-lactamase 0.0036 0.0078 0.029
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0063 0.0183 0.0683
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1058 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0063 0.0183 0.0683

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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