Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0026 | 0.0043 |
Brugia malayi | Choline O-acetyltransferase | 0.0145 | 0.0368 | 0.0755 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.003 | 0.006 | 0.0113 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0048 | 0.0107 | 0.1203 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.004 | 0.0087 | 0.0169 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0145 | 0.0368 | 0.1728 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0261 | 0.0683 | 0.0678 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.004 | 0.0087 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0321 | 0.0656 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0091 | 0.0225 | 0.0456 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0203 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.018 | 0.0363 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0122 | 0.0242 |
Schistosoma mansoni | lamin | 0.0062 | 0.0146 | 0.014 |
Mycobacterium tuberculosis | Conserved protein | 0.0048 | 0.0107 | 0.1203 |
Onchocerca volvulus | 0.0062 | 0.0146 | 0.105 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.0031 | 0.0266 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0145 | 0.0368 | 0.1728 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0048 | 0.0107 | 0.0102 |
Echinococcus multilocularis | tumor protein p63 | 0.0511 | 0.1357 | 0.1352 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0048 | 0.0107 | 0.0485 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.179 | 0.4809 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0145 | 0.0368 | 0.1728 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0048 | 0.0107 | 0.1203 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0014 | 0.0017 | 0.0309 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0043 | 0.0369 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0048 | 0.0107 | 0.0922 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0013 | 0.0012 | 0.018 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0145 | 0.0368 | 0.0363 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0048 | 0.0107 | 0.1203 |
Schistosoma mansoni | microtubule-associated protein tau | 0.3713 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0048 | 0.0107 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0056 | 0.0105 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0145 | 0.0368 | 1 |
Onchocerca volvulus | 0.0048 | 0.0107 | 0.0712 | |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0145 | 0.0368 | 0.0363 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0083 | 0.0203 | 0.0198 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0018 | 0.0026 | 0.1305 |
Schistosoma mansoni | lamin | 0.0062 | 0.0146 | 0.014 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0022 | 0.0189 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0145 | 0.0368 | 0.0755 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0087 | 0.0081 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0203 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0095 | 0.0236 | 0.023 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0018 | 0.0026 | 0.0099 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.003 | 0.006 | 0.1884 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0013 | 0.0014 | 0.0025 |
Brugia malayi | AMP-binding enzyme family protein | 0.0018 | 0.0026 | 0.0043 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0083 | 0.0203 | 0.0198 |
Brugia malayi | intermediate filament protein | 0.0062 | 0.0146 | 0.0292 |
Brugia malayi | Pre-SET motif family protein | 0.0386 | 0.1021 | 0.2114 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0788 | 0.2105 | 0.2101 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0088 | 0.0216 | 0.0211 |
Loa Loa (eye worm) | beta-lactamase | 0.0048 | 0.0107 | 0.0212 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.001 | 0.0005 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0014 | 0.0018 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.003 | 0.006 | 0.0258 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0018 | 0.0026 | 0.1305 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.003 | 0.006 | 0.0258 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0088 | 0.0216 | 0.0211 |
Onchocerca volvulus | 0.0145 | 0.0368 | 0.3003 | |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.004 | 0.0087 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0059 | 0.0112 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0048 | 0.0107 | 0.0922 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0048 | 0.0107 | 0.0485 |
Trichomonas vaginalis | esterase, putative | 0.0048 | 0.0107 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0107 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0143 | 0.0286 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0022 | 0.019 |
Brugia malayi | beta-lactamase family protein | 0.0048 | 0.0107 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0026 | 0.0043 |
Mycobacterium leprae | conserved hypothetical protein | 0.0048 | 0.0107 | 1 |
Brugia malayi | hypothetical protein | 0.0083 | 0.0203 | 0.0411 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0048 | 0.0107 | 1 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0145 | 0.0368 | 0.0755 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0145 | 0.0368 | 0.1728 |
Toxoplasma gondii | ABC1 family protein | 0.0048 | 0.0107 | 0.7715 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0024 | 0.0043 | 0.1035 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0055 | 0.0128 | 0.0122 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0048 | 0.0107 | 0.2809 |
Mycobacterium leprae | Probable lipase LipE | 0.0048 | 0.0107 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0203 | 0.0198 |
Schistosoma mansoni | tar DNA-binding protein | 0.0059 | 0.0139 | 0.0133 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0145 | 0.0368 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0122 | 0.0116 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0386 | 0.1021 | 0.2114 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.003 | 0.0059 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.006 | 0.0512 |
Schistosoma mansoni | hypothetical protein | 0.0088 | 0.0216 | 0.0211 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0018 | 0.0026 | 0.0099 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0026 | 0.0179 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0022 | 0.0039 | 0.0332 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0122 | 0.0116 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0013 | 0.0014 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0026 | 0.0226 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0048 | 0.0107 | 0.0102 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0048 | 0.0107 | 0.1203 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0261 | 0.0683 | 0.0678 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.003 | 0.006 | 0.0054 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0018 | 0.0026 | 0.0179 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0022 | 0.0039 | 0.0332 |
Mycobacterium ulcerans | beta-lactamase | 0.0048 | 0.0107 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0018 | 0.0026 | 0.1305 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.001 | 0.0005 | 0.0047 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0055 | 0.0128 | 0.0122 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0018 | 0.0026 | 0.1305 |
Plasmodium vivax | hypothetical protein, conserved | 0.0048 | 0.0107 | 0.821 |
Echinococcus granulosus | lamin | 0.0062 | 0.0146 | 0.014 |
Loa Loa (eye worm) | TAR-binding protein | 0.0059 | 0.0139 | 0.0277 |
Mycobacterium tuberculosis | Conserved protein | 0.0048 | 0.0107 | 0.1203 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.004 | 0.0087 | 0.0081 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.003 | 0.006 | 0.0054 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0048 | 0.0107 | 0.1203 |
Onchocerca volvulus | 0.0145 | 0.0368 | 0.3003 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.006 | 0.0512 |
Brugia malayi | Choline O-acetyltransferase | 0.0145 | 0.0368 | 0.0755 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0018 | 0.0026 | 0.1305 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.001 | 0.0005 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0087 | 0.0081 |
Trichomonas vaginalis | set domain proteins, putative | 0.044 | 0.1165 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0022 | 0.019 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0145 | 0.0368 | 0.1728 |
Schistosoma mansoni | intermediate filament proteins | 0.0062 | 0.0146 | 0.014 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0022 | 0.0039 | 0.0332 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0022 | 0.0189 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0055 | 0.0128 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0048 | 0.0107 | 0.1203 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0145 | 0.0368 | 0.0363 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0018 | 0.0026 | 0.1305 |
Schistosoma mansoni | tar DNA-binding protein | 0.0059 | 0.0139 | 0.0133 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0043 | 0.0369 |
Onchocerca volvulus | 0.0145 | 0.0368 | 0.3003 | |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0033 | 0.0068 | 0.013 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0024 | 0.0043 | 0.0179 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0203 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0026 | 0.0226 |
Schistosoma mansoni | tar DNA-binding protein | 0.0059 | 0.0139 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.0368 | 0.0755 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0043 | 0.0369 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.003 | 0.006 | 0.0258 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0145 | 0.0368 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0087 | 0.0081 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0022 | 0.019 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0145 | 0.0368 | 0.0755 |
Giardia lamblia | GTOR | 0.003 | 0.006 | 0.5 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0145 | 0.0368 | 0.0755 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0062 | 0.0146 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.179 | 0.4809 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.003 | 0.0059 | 0.0054 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0145 | 0.0368 | 0.1728 |
Echinococcus multilocularis | GPCR, family 2 | 0.004 | 0.0087 | 0.0081 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0048 | 0.0107 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0146 | 0.0292 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0145 | 0.0368 | 0.1728 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.3713 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0127 | 0.0321 | 0.0656 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0048 | 0.0107 | 0.0922 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0014 | 0.0018 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0048 | 0.0409 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0055 | 0.0128 | 0.0122 |
Leishmania major | hypothetical protein, conserved | 0.0048 | 0.0107 | 0.0485 |
Brugia malayi | beta-lactamase family protein | 0.0048 | 0.0107 | 0.0212 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0048 | 0.0107 | 0.0212 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0127 | 0.0321 | 0.0656 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0018 | 0.0026 | 0.1305 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0128 | 0.0255 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0043 | 0.0369 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0048 | 0.0107 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0014 | 0.0018 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.003 | 0.006 | 0.1492 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0022 | 0.019 |
Onchocerca volvulus | 0.0048 | 0.0107 | 0.0712 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.004 | 0.0087 | 0.0169 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.003 | 0.006 | 0.0258 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0087 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0107 | 0.0212 |
Brugia malayi | Pre-SET motif family protein | 0.0055 | 0.0128 | 0.0255 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0107 | 0.0212 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0145 | 0.0368 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0048 | 0.0107 | 1 |
Brugia malayi | RNA binding protein | 0.0059 | 0.0139 | 0.0277 |
Echinococcus granulosus | GPCR family 2 | 0.004 | 0.0087 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0261 | 0.0683 | 0.141 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0014 | 0.0018 |
Schistosoma mansoni | choline o-acyltransferase | 0.0145 | 0.0368 | 0.0363 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0145 | 0.0368 | 0.1728 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0062 | 0.0146 | 0.0292 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0075 | 0.018 | 0.0175 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.003 | 0.006 | 0.1492 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0022 | 0.0039 | 0.0332 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0018 | 0.0026 | 0.0099 |
Onchocerca volvulus | 0.0062 | 0.0146 | 0.105 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0026 | 0.0043 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.003 | 0.006 | 0.0113 |
Onchocerca volvulus | 0.0048 | 0.0107 | 0.0712 | |
Loa Loa (eye worm) | intermediate filament protein | 0.0062 | 0.0146 | 0.0292 |
Plasmodium vivax | SET domain protein, putative | 0.0055 | 0.0128 | 1 |
Brugia malayi | TAR-binding protein | 0.0059 | 0.0139 | 0.0277 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0145 | 0.0368 | 0.0755 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.006 | 0.0512 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0203 | 1 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0145 | 0.0368 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0091 | 0.0225 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0014 | 0.0018 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0055 | 0.0128 | 0.0122 |
Brugia malayi | Latrophilin receptor protein 2 | 0.004 | 0.0087 | 0.0169 |
Onchocerca volvulus | 0.044 | 0.1165 | 1 | |
Echinococcus granulosus | choline O acetyltransferase | 0.0145 | 0.0368 | 0.0363 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0022 | 0.0039 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0212 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.0683 | 0.141 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0048 | 0.0107 | 0.0922 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0788 | 0.2105 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0062 | 0.0146 | 0.014 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.001 | 0.0005 | 0.0047 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0145 | 0.0368 | 0.1728 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0033 | 0.0068 | 0.013 |
Echinococcus multilocularis | lamin | 0.0062 | 0.0146 | 0.014 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.004 | 0.0087 | 0.0081 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.001 | 0.0005 | 0.0047 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.003 | 0.006 | 0.1884 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0022 | 0.0189 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0145 | 0.0368 | 0.1728 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0055 | 0.0128 | 0.0122 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0212 | 0.0207 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0145 | 0.0368 | 0.1728 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0024 | 0.0043 | 0.0179 |
Schistosoma mansoni | tar DNA-binding protein | 0.0059 | 0.0139 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0107 | 0.0212 |
Brugia malayi | AMP-binding enzyme family protein | 0.0018 | 0.0026 | 0.0043 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0788 | 0.2105 | 1 |
Onchocerca volvulus | 0.0053 | 0.0122 | 0.0839 | |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0048 | 0.0107 | 0.1203 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0048 | 0.0107 | 0.1203 |
Echinococcus granulosus | intermediate filament protein | 0.0062 | 0.0146 | 0.014 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0059 | 0.0139 | 0.0277 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0087 | 0.0212 | 0.0431 |
Schistosoma mansoni | tar DNA-binding protein | 0.0059 | 0.0139 | 0.0133 |
Echinococcus granulosus | tumor protein p63 | 0.0511 | 0.1357 | 0.1352 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0127 | 0.0321 | 0.0656 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0091 | 0.0225 | 0.0456 |
Echinococcus granulosus | tar DNA binding protein | 0.0059 | 0.0139 | 0.0133 |
Brugia malayi | beta-lactamase | 0.0048 | 0.0107 | 0.0212 |
Onchocerca volvulus | 0.0055 | 0.0128 | 0.0891 | |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0788 | 0.2105 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.0107 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0018 | 0.0026 | 0.0043 |
Schistosoma mansoni | thyroid hormone receptor | 0.0095 | 0.0236 | 0.023 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.0033 | 0.0281 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0022 | 0.0039 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0107 | 0.0212 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0053 | 0.0122 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0056 | 0.0105 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0306 | 0.0804 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0048 | 0.0107 | 0.0212 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.003 | 0.006 | 0.0054 |
Onchocerca volvulus | 0.0145 | 0.0368 | 0.3003 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0083 | 0.0203 | 0.0198 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0059 | 0.0139 | 0.0277 |
Schistosoma mansoni | choline o-acyltransferase | 0.0145 | 0.0368 | 0.0363 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0145 | 0.0368 | 0.1728 |
Echinococcus multilocularis | musashi | 0.0062 | 0.0146 | 0.014 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0145 | 0.0368 | 0.1728 |
Onchocerca volvulus | 0.0075 | 0.018 | 0.135 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0027 | 0.023 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0026 | 0.1305 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0055 | 0.0128 | 0.0122 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0788 | 0.2105 | 0.2101 |
Echinococcus granulosus | lamin dm0 | 0.0062 | 0.0146 | 0.014 |
Echinococcus multilocularis | tar DNA binding protein | 0.0059 | 0.0139 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0087 | 0.0169 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0013 | 0.0014 | 0.5 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0048 | 0.0107 | 0.0102 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0027 | 0.023 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0027 | 0.023 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0055 | 0.0128 | 0.0122 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0095 | 0.0236 | 0.023 |
Loa Loa (eye worm) | RNA binding protein | 0.0059 | 0.0139 | 0.0277 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0043 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0107 | 0.0212 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0022 | 0.0039 | 0.0332 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | < 5 % | Inhibition of methyl transferase activity of SET7/9 at 50 uM using biotinylated histone H3(1-21) substrate by In-vitro time resolved fluorescence immunosorbent methyltransferase assay | ChEMBL. | 21440447 |
Inhibition (binding) | = 35.3 % | Inhibition of human recombinant PRMT1-mediated arginine methylation at 10 uM using nonhistone protein Npl3 substrate by ELISA | ChEMBL. | 21440447 |
Inhibition (binding) | = 41.2 % | Inhibition of human recombinant PRMT1-mediated arginine methylation at 50 uM using nonhistone protein Npl3 substrate by ELISA | ChEMBL. | 21440447 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.