Detailed information for compound 1615848

Basic information

Technical information
  • TDR Targets ID: 1615848
  • Name: methyl 4-(2-aminoethylamino)-8-(chloromethyl) -6-(5,6,7-trimethoxy1H-indole-2-carbonyl)-7,8 -dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylat e hydrochloride
  • MW: 592.471 | Formula: C27H31Cl2N5O6
  • H donors: 4 H acceptors: 2 LogP: 3.89 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: NCCNc1cc2N(CC(c2c2c1[nH]c(c2)C(=O)OC)CCl)C(=O)c1cc2c([nH]1)c(OC)c(c(c2)OC)OC.Cl
  • InChi: 1S/C27H30ClN5O6.ClH/c1-36-20-8-13-7-17(31-22(13)25(38-3)24(20)37-2)26(34)33-12-14(11-28)21-15-9-18(27(35)39-4)32-23(15)16(10-19(21)33)30-6-5-29;/h7-10,14,30-32H,5-6,11-12,29H2,1-4H3;1H
  • InChiKey: VATFORKEFUIOMK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(2-aminoethylamino)-8-(chloromethyl)-6-[oxo-(5,6,7-trimethoxy-1H-indol-2-yl)methyl]-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylic acid methyl ester hydrochloride
  • 4-(2-aminoethylamino)-8-(chloromethyl)-6-(5,6,7-trimethoxy1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylic acid methyl ester hydrochloride
  • methyl 4-(2-aminoethylamino)-8-(chloromethyl)-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate hydrochloride
  • NSC701745

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0045 0.0093 0.0093
Plasmodium falciparum tyrosine kinase-like protein 0.0045 0.0093 0.0248
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0164 0.0565 0.0565
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0052 0.0122 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.1702 0.668 0.668
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0181 0.0181
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis heat shock protein 70 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0164 0.0565 0.0565
Echinococcus granulosus activated cdc42 kinase 1 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0565 0.0488
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0164 0.0565 0.0565
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0164 0.0565 0.0488
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0045 0.0093 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis Glutaredoxin protein 5 0.0041 0.0079 0.0079
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi Tyrosine-protein kinase abl-1 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.2018 0.7936 0.7936
Trichomonas vaginalis PIKK family atypical protein kinase 0.1647 0.6462 0.6462
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0052 0.0122 0.0042
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Giardia lamblia Kinase, NEK 0.0045 0.0093 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/INSR protein kinase 0.0045 0.0093 0.0093
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0164 0.0565 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0164 0.0565 0.0565
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0045 0.0093 0.0093
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0477
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0164 0.0565 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.7416 0.7416
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Leishmania major hypothetical protein, unknown function 0.0164 0.0565 0.0477
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis 0.0164 0.0565 0.0565
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0052 0.0122 0.0122
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis ephrin type A receptor 4 A 0.0045 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0052 0.0122 0.0122
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/ACK protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0164 0.0565 0.0565
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi target of rapamycin kinase 3 0.202 0.7945 0.7928
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Plasmodium falciparum tyrosine kinase-like protein 0.0045 0.0093 0.0248
Echinococcus multilocularis tyrosine protein kinase Srms 0.0045 0.0093 0.0093
Echinococcus granulosus serine protein kinase ATM 0.048 0.1822 0.1822
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0045 0.0093 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0164 0.0565 0.0565
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0164 0.0565 0.0565
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0045 0.0093 0.0093
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0164 0.0565 0.0565
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Plasmodium falciparum protein kinase, putative 0.0045 0.0093 0.0248
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0234 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0316 0.1171 0.1171
Echinococcus granulosus receptor type guanylyl cyclase 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0164 0.0565 0.0488
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0164 0.0565 0.0645
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.048 0.1822 0.1755
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase HCK 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0164 0.0565 0.0565
Echinococcus multilocularis tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0164 0.0565 0.0565
Trypanosoma brucei rac serine-threonine kinase, putative 0.0067 0.0181 0.0089
Loa Loa (eye worm) TK/DDR protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein, conserved 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) phosphatidylinositol 3 0.0164 0.0565 0.0565
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0093 0.0093
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0045 0.0093 0.0093
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0045 0.0093 0.0093
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0045 0.0093 0.0093
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis protein kinase atn1, putative 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0164 0.0565 0.0565
Echinococcus granulosus retinal guanylyl cyclase 2 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0164 0.0565 0.0488
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis serine protein kinase ATM 0.048 0.1822 0.1822
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0164 0.0565 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.2018 0.7936 0.7936
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi hypothetical protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0164 0.0565 0.0565
Echinococcus granulosus epidermal growth factor receptor 0.0045 0.0093 0.0093
Echinococcus multilocularis activated cdc42 kinase 1 0.0045 0.0093 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0181 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0164 0.0565 0.0565
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0851 0.3297 0.3297
Trypanosoma cruzi protein kinase, putative 0.0045 0.0093 0.0012
Echinococcus multilocularis integrin linked protein kinase 0.0045 0.0093 0.0093
Giardia lamblia Kinase, NEK 0.0045 0.0093 0.0012
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.048 0.1822 0.1822
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) SRC-1 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0045 0.0093 0.0093
Loa Loa (eye worm) phosphatidylinositol kinase 0.0164 0.0565 0.0565
Echinococcus granulosus tyrosine protein kinase Srms 0.0045 0.0093 0.0093
Giardia lamblia Kinase 0.0045 0.0093 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus retinal guanylyl cyclase 2 0.0045 0.0093 0.0093
Brugia malayi hypothetical protein 0.0045 0.0093 0.0093
Schistosoma mansoni serine/threonine RGC 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0164 0.0565 0.0645
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0052 0.0122 0.0122
Echinococcus granulosus Glutaredoxin protein 5 0.0041 0.0079 0.0079
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.005 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0371 0.1389 0.1389
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Echinococcus granulosus retinal guanylyl cyclase 2 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0535 0.204 0.204
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0042 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0045 0.0093 0.0093
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0045 0.0093 0.0093
Leishmania major protein kinase, putative 0.0045 0.0094 0.0002
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0565
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0164 0.0565 0.0477
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0164 0.0565 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0164 0.0565 0.0565
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0851 0.3297 0.3234
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0181 0.0181
Echinococcus granulosus protein tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1368 0.5352 0.5352
Loa Loa (eye worm) phosphatidylinositol 3 0.0851 0.3297 0.3297
Echinococcus granulosus tyrosine protein kinase ABL1 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/EGFR protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0052 0.0122 0.0122
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0069 0.0188 0.0188
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0164 0.0565 0.0565
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0164 0.0565 0.0565
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0063 0.0165 0.0165
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0851 0.3297 0.3242
Brugia malayi Protein kinase domain containing protein 0.0067 0.0181 0.0181
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.1054 0.4103 0.4048
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase csk 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.7416 0.7416
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0045 0.0093 0.0093
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0045 0.0094 0.0014
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.048 0.1822 0.1745
Entamoeba histolytica hypothetical protein 0.0164 0.0565 0.0565
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.0565 0.5
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0164 0.0565 0.0565
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.048 0.1822 0.1755
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0045 0.0093 0.0093
Schistosoma mansoni immunophilin 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.048 0.1822 0.1822
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Brugia malayi SRC-1 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica receptor protein kinase, putative 0.0045 0.0093 0.0093
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0052 0.0122 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/ABL protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) AGC/AKT protein kinase 0.0067 0.0181 0.0181
Entamoeba histolytica hypothetical protein 0.005 0.0113 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0074 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis rac serine:threonine kinase 0.0046 0.0097 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.137 0.536 0.536
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0164 0.0565 0.0565
Plasmodium vivax tyrosine kinase-like protein, putative 0.0045 0.0093 0.0248
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis natriuretic peptide receptor 1 0.0045 0.0093 0.0093
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0565 0.0477
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0164 0.0565 0.0565
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0164 0.0565 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0181 0.0181
Echinococcus granulosus tyrosine protein kinase Blk 0.0045 0.0093 0.0093
Echinococcus granulosus integrin linked protein kinase 0.0045 0.0093 0.0093
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.12 0.4684 0.4634
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Schistosoma mansoni ephrin receptor 0.0045 0.0093 0.0093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0164 0.0565 0.0565
Echinococcus granulosus tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.005 0.0113 0.0113
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Schistosoma mansoni protein tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0045 0.0094 0.0014
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Plasmodium vivax protein kinase, putative 0.0045 0.0093 0.0248
Brugia malayi Receptor family ligand binding region containing protein 0.0045 0.0093 0.0093
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0045 0.0093 0.0093
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0164 0.0565 0.0565
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0164 0.0565 0.0488
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1501 0.5881 0.5881
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0045 0.0093 0.0093
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0164 0.0565 0.0565
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0164 0.0565 1
Trichomonas vaginalis protein tyrosine kinase, putative 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus serine threonine protein kinase nrc 0.0042 0.0081 0.0081
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0164 0.0565 0.0565
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) phosphatidylinositol 3 0.0164 0.0565 0.0565
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0164 0.0565 0.0565
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni immunophilin 0.0052 0.0122 0.0122
Giardia lamblia Phosphatidylinositol 4-kinase 0.0164 0.0565 0.0488
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0052 0.0122 0.0122
Brugia malayi FAT domain containing protein 0.0371 0.1389 0.1389
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0851 0.3297 0.3297
Loa Loa (eye worm) hypothetical protein 0.0316 0.1171 0.1171
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0234 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0164 0.0565 0.0565
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0164 0.0565 0.0565
Leishmania major phosphatidylinositol kinase, putative 0.0164 0.0565 0.0477
Loa Loa (eye worm) TK/EPH protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0164 0.0565 0.0565
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0371 0.1389 0.1389
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0052 0.0122 0.0122
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0851 0.3297 0.3297
Echinococcus multilocularis insulin receptor 0.0045 0.0093 0.0093
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.202 0.7945 0.7925
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0093 0.0093
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0052 0.0122 0.5
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.048 0.1822 0.1822
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.048 0.1822 0.1822
Leishmania major phosphatidylinositol 4-kinase, putative 0.0164 0.0565 0.0477
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0851 0.3297 0.3234
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0535 0.204 0.2659
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0164 0.0565 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0535 0.204 0.204
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0164 0.0565 0.0565
Echinococcus granulosus epidermal growth factor receptor 0.0045 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0045 0.0094 0.0002
Plasmodium falciparum protein kinase, putative 0.0045 0.0094 0.0286
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0094 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.137 0.536 0.536
Echinococcus granulosus raf serine:threonine protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Toxoplasma gondii FATC domain-containing protein 0.048 0.1822 0.2361
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Brugia malayi bone morphogenetic protein type 1 receptor 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FAK protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0164 0.0565 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0164 0.0565 0.0565
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0045 0.0093 0.0093
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.048 0.1822 0.1822
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Brugia malayi ephrin receptor 1 precursor 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0067 0.0181 0.0181
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosin kinase, putative 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase pr2 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0045 0.0093 0.0093
Echinococcus granulosus kinase suppressor of Ras 1 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1516 0.5941 0.5941
Loa Loa (eye worm) TK/Met protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0164 0.0565 0.0565
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0164 0.0565 0.0645
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi C-terminal src kinase protein 1 0.0045 0.0093 0.0093
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0052 0.0122 0.0122
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0164 0.0565 0.0565
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0074 0.0207 0.0207
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis activin receptor type 0.0045 0.0094 0.0094
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0164 0.0565 0.0645
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0316 0.1171 0.1099
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0045 0.0093 0.0093
Schistosoma mansoni serine/threonine-protein kinase 0.0046 0.0097 0.0097
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Onchocerca volvulus 0.0164 0.0565 1
Entamoeba histolytica tyrosin kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Echinococcus granulosus fibroblast growth factor receptor 4 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosin kinase, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.137 0.536 0.536
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Toxoplasma gondii target of rapamycin (TOR), putative 0.1887 0.7416 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0041 0.0079 0.0079
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0046 0.0097 0.0017
Echinococcus granulosus activin receptor type 0.0045 0.0094 0.0094
Echinococcus multilocularis tyrosine kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TK family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus c src tyrosine kinase 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosin kinase, putative 0.0045 0.0093 0.0093
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0052 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Leishmania major fk506-binding protein 1-like protein 0.0052 0.0122 0.003
Echinococcus granulosus nervana 2 0.0041 0.0079 0.0079
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0045 0.0093 0.0093
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0164 0.0565 0.0565
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0371 0.1389 0.1389
Echinococcus granulosus tyrosine protein kinase Src42A 0.0045 0.0093 0.0093
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0164 0.0565 0.0565
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0681 0.262 0.262
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0042 0.0081 0.0081
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0851 0.3297 0.3297
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0851 0.3297 0.3234
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/ALK protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0164 0.0565 0.0565
Echinococcus granulosus serine:threonine protein kinase SMG1 0.048 0.1822 0.1822
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.7416 0.7416
Loa Loa (eye worm) phosphatidylinositol 3 0.0164 0.0565 0.0565
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0164 0.0565 0.0565
Schistosoma mansoni serine/threonine-protein kinase 0.0046 0.0097 0.0097
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0041 0.0079 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0851 0.3297 0.3297
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0045 0.0094 0.0094
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0164 0.0565 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.2018 0.7936 0.7936
Echinococcus multilocularis tyrosine protein kinase pr2 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0045 0.0093 0.0093
Echinococcus multilocularis epidermal growth factor receptor 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Brugia malayi Raf kinase 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0045 0.0093 0.0093
Echinococcus granulosus natriuretic peptide receptor 1 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Toxoplasma gondii AGC kinase 0.0063 0.0165 0.0098
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0074 0.0207 0.0207
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0052 0.0122 0.003
Brugia malayi Furin-like cysteine rich region family protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) serine/threonine protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1516 0.5941 0.5941
Leishmania major phosphatidylinositol kinase related protein, putative 0.0164 0.0565 0.0477
Echinococcus multilocularis c src tyrosine kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0067 0.0181 0.0181
Echinococcus granulosus nervana 2 0.0041 0.0079 0.0079
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0164 0.0565 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0851 0.3297 0.3297
Trichomonas vaginalis PIKK family atypical protein kinase 0.137 0.536 0.536
Entamoeba histolytica hypothetical protein 0.048 0.1822 0.1822
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0164 0.0565 0.0477
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0045 0.0093 0.0093
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0164 0.0565 0.0565
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0164 0.0565 0.0488
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0045 0.0094 0.0094
Echinococcus granulosus activated cdc42 kinase 1 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0052 0.0122 0.0853
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0164 0.0565 1
Brugia malayi integrin-linked kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.7416 0.7416
Schistosoma mansoni protein kinase 0.0045 0.0094 0.0094
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0164 0.0565 0.0565
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Abl 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis STE family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0045 0.0093 0.0093
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0371 0.1389 0.1389
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0093 0.0093
Giardia lamblia Protein 21.1 0.0045 0.0093 0.0012
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0045 0.0093 0.0093
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0565
Plasmodium vivax tyrosine kinase-like protein, putative 0.0045 0.0093 0.0248
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.005 0.0113 0.0113
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.048 0.1822 0.1822
Schistosoma mansoni hypothetical protein 0.0164 0.0565 0.0565
Echinococcus multilocularis fk506 binding protein 0.0052 0.0122 0.0122
Echinococcus multilocularis raf serine:threonine protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis nervana 2 0.0041 0.0079 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Echinococcus multilocularis nervana 2 0.0041 0.0079 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis Zinc finger, PHD finger 0.0164 0.0565 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1171 0.1171
Loa Loa (eye worm) hypothetical protein 0.0517 0.197 0.197
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.1389 0.1389
Trypanosoma cruzi protein kinase, putative 0.0045 0.0093 0.0012
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) protein kinase domain-containing protein 0.0045 0.0093 0.0093
Trypanosoma brucei target of rapamycin kinase 3, putative 0.202 0.7945 0.7925
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.048 0.1822 0.1822
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0052 0.0122 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.048 0.1822 0.1822
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0045 0.0093 0.0093
Echinococcus granulosus protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0064 0.0168 0.0168
Entamoeba histolytica hypothetical protein 0.0164 0.0565 0.0565
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0164 0.0565 0.0565
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0122 0.003
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0052 0.0122 0.0122
Entamoeba histolytica serine/threonine kinase, putative 0.0045 0.0093 0.0093
Schistosoma mansoni ephrin receptor 0.0045 0.0093 0.0093
Echinococcus multilocularis FL cytokine receptor 0.0045 0.0093 0.0093
Echinococcus multilocularis protein tyrosine kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0164 0.0565 0.0565
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0851 0.3297 0.3297
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0045 0.0093 0.0093
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0565
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0122 0.0042
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0851 0.3297 0.3297
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0052 0.0122 0.0853
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0488
Echinococcus granulosus tyrosine protein kinase Src64B 0.0045 0.0093 0.0093
Onchocerca volvulus 0.0164 0.0565 1
Echinococcus granulosus tyrosine protein kinase shark 0.0045 0.0093 0.0093
Trichomonas vaginalis immunophilin, putative 0.0052 0.0122 0.0122
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0181 0.0181
Echinococcus multilocularis protein KINase family member (kin 25) 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.7416 0.7416
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0045 0.0093 0.0093
Loa Loa (eye worm) phosphatidylinositol 3 0.0164 0.0565 0.0565
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Loa Loa (eye worm) phosphatidylinositol 3 0.0164 0.0565 0.0565
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.005 0.0113 0.0113
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0093 0.0093
Plasmodium vivax hypothetical protein, conserved 0.0164 0.0565 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0093 0.0093
Plasmodium vivax hypothetical protein 0.0164 0.0565 1
Brugia malayi Guanylyl cyclase protein 23 0.0045 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0074 0.0207 0.0207
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0052 0.0122 0.0042
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Brugia malayi hypothetical protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0164 0.0565 0.0645
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis epidermal growth factor receptor 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0164 0.0565 0.0488
Entamoeba histolytica cysteine surface protein, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.7416 0.7416
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine kinase 0.0045 0.0093 0.0093
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0052 0.0122 0.0042
Entamoeba histolytica serine/threonine kinase, putative 0.0045 0.0093 0.0093
Giardia lamblia Hypothetical protein 0.0164 0.0565 0.0488
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/CSK protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0164 0.0565 0.0565
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis transfer RNA-Thr 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase csk 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0164 0.0565 0.0488
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1368 0.5352 0.5352
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0045 0.0094 0.0003
Loa Loa (eye worm) FKBP5 protein 0.0052 0.0122 0.0122
Schistosoma mansoni protein kinase 0.0045 0.0094 0.0094
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0052 0.0122 0.0122
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Lyn 0.0045 0.0094 0.0094
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0045 0.0093 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0164 0.0565 0.0565
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase rad3, putative 0.048 0.1822 0.1822
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0122 0.0042
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0063 0.0165 0.0165
Echinococcus multilocularis tyrosine protein kinase shark 0.0045 0.0093 0.0093
Leishmania major phosphatidylinositol 3-kinase, putative 0.0851 0.3297 0.3234
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0164 0.0565 0.0488
Entamoeba histolytica protein kinase 2, putative 0.0042 0.0081 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0851 0.3297 0.3297
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0164 0.0565 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.048 0.1822 0.1822
Trypanosoma brucei protein kinase, putative 0.0045 0.0094 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Brugia malayi Tyrosine-protein kinase PR2 0.0045 0.0093 0.0093
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0164 0.0565 0.0565
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1368 0.5352 0.5352
Entamoeba histolytica ankyrin repeat protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0164 0.0565 0.0565
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0045 0.0094 0.0094
Schistosoma mansoni fkbp-rapamycin associated protein 0.048 0.1822 0.1822
Trichomonas vaginalis PIKK family atypical protein kinase 0.2018 0.7936 0.7936
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0565 0.0488
Echinococcus granulosus serine/threonine protein kinase 0.0046 0.0097 0.0097
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0164 0.0565 0.0565
Trichomonas vaginalis PIKK family atypical protein kinase 0.1501 0.5881 0.5881
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0093 0.0093
Echinococcus granulosus ephrin type A receptor 4 A 0.0045 0.0093 0.0093
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0565
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0045 0.0093 0.0093
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.2018 0.7936 0.7936
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0093
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0565
Echinococcus multilocularis tyrosine protein kinase HCK 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase csk 0.0045 0.0093 0.0093
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0045 0.0093 0.0093
Brugia malayi SH2 domain containing protein 0.0045 0.0093 0.0093
Plasmodium falciparum protein kinase, putative 0.0045 0.0093 0.0248
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0181 0.0181
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0164 0.0565 0.0477
Leishmania major peptidylprolyl isomerase-like protein 0.0052 0.0122 0.003
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine kinase 0.0045 0.0093 0.0093
Entamoeba histolytica protein kinase, putative 0.0045 0.0093 0.0093
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0069 0.0188 0.0188
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0045 0.0093 0.0093
Leishmania major hypothetical protein, conserved 0.0164 0.0565 0.0477
Echinococcus multilocularis tyrosine protein kinase Blk 0.0045 0.0093 0.0093
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0045 0.0093 0.0093
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0045 0.0093 0.0093
Trypanosoma cruzi Protein kinase B 0.0046 0.0097 0.0017
Trichomonas vaginalis fk506-binding protein, putative 0.0052 0.0122 0.0122
Brugia malayi SH2 domain containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0045 0.0093 0.0093
Leishmania major phosphatidylinositol 3-kinase, putative 0.0164 0.0565 0.0477
Entamoeba histolytica ankyrin repeat protein 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Loa Loa (eye worm) TK/RYK protein kinase 0.0045 0.0093 0.0093
Schistosoma mansoni tyrosine protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.7416 0.7416
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0045 0.0093 0.0093
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0851 0.3297 0.3242
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica hypothetical protein 0.0045 0.0093 0.0093
Echinococcus granulosus insulin receptor 0.0045 0.0093 0.0093
Schistosoma mansoni immunophilin 0.0052 0.0122 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0181 0.0181
Echinococcus multilocularis tyrosine protein kinase 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.2166 0.8525 0.8525
Echinococcus multilocularis kinase suppressor of Ras 1 0.0045 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0045 0.0093 0.0093
Entamoeba histolytica receptor protein kinase, putative 0.0045 0.0093 0.0093
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0164 0.0565 0.0488
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0093 0.0093
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0093 0.0093
Echinococcus multilocularis protein kinase 0.0045 0.0093 0.0093
Brugia malayi p70 ribosomal S6 kinase beta 0.0063 0.0165 0.0165
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0164 0.0565 0.0565
Brugia malayi protein-tyrosine kinase 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.1516 0.5941 0.5941
Mycobacterium leprae conserved hypothetical protein 0.0164 0.0565 0.5
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0164 0.0565 1

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -7.655 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.504 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.407 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.181 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.153 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.091 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.051 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.008 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.717 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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