Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Protein patched homolog 1 | 0.0044 | 0.0086 | 0.0279 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0063 | 0.0278 | 0.0356 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0038 | 0.0033 | 0.0041 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0086 | 0.0424 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0023 | 0.0073 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0591 | 0.5452 | 0.6897 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0063 | 0.0278 | 0.0093 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0063 | 0.0278 | 0.0093 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0832 | 0.7812 | 1 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0175 | 0.137 | 0.1753 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.1384 | 0.4951 |
Mycobacterium ulcerans | acyl carrier protein | 0.0056 | 0.0207 | 0.0265 |
Brugia malayi | hypothetical protein | 0.0127 | 0.0905 | 0.0905 |
Brugia malayi | AMP-binding enzyme family protein | 0.0172 | 0.1343 | 0.1343 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0146 | 0.1091 | 0.1376 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0556 | 0.5113 | 0.6545 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0306 | 0.2357 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.014 | 0.1025 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Mycobacterium ulcerans | polyketide synthase | 0.0556 | 0.5113 | 0.6545 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0146 | 0.1091 | 0.3516 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.014 | 0.1025 | 1 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0102 | 0.066 | 1 |
Echinococcus multilocularis | expressed conserved protein | 0.0096 | 0.0599 | 0.0755 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0057 | 0.0217 | 0.0013 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0368 | 0.3265 | 0.4179 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0591 | 0.5452 | 0.6897 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0361 | 0.3196 | 0.5851 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0455 | 0.4119 | 0.5143 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.014 | 0.1025 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0368 | 0.3265 | 0.4179 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0493 | 0.0558 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0246 | 0.2068 | 0.2608 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0085 | 0.0493 | 0.0376 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0023 | 0.0028 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0556 | 0.5113 | 0.6545 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.016 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0936 | 0.8834 | 1 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0556 | 0.5113 | 0.5113 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0061 | 0.025 | 0.2436 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0591 | 0.5452 | 0.6979 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0556 | 0.5113 | 0.6545 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0085 | 0.0493 | 0.0376 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0071 | 0.0254 |
Mycobacterium leprae | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0057 | 0.0217 | 0.0013 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0527 | 0.4826 | 0.5463 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0038 | 0.0033 | 0.0041 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0306 | 0.2987 |
Brugia malayi | hypothetical protein | 0.0246 | 0.2068 | 0.2068 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.014 | 0.1025 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0351 | 0.3102 | 0.3913 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.016 | 0.0572 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0183 | 0.0208 |
Mycobacterium ulcerans | polyketide synthase | 0.0591 | 0.5452 | 0.6979 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0056 | 0.0207 | 0.2016 |
Schistosoma mansoni | lipoxygenase | 0.0123 | 0.0859 | 0.3071 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0191 | 0.1532 | 0.1742 |
Leishmania major | hypothetical protein, conserved | 0.0168 | 0.13 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0057 | 0.0217 | 0.3046 |
Echinococcus granulosus | tumor protein p63 | 0.0351 | 0.3102 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0306 | 0.2987 |
Echinococcus granulosus | NADH dehydrogenase | 0.0056 | 0.0207 | 0.0666 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0063 | 0.0278 | 0.0356 |
Mycobacterium ulcerans | thioesterase TesA | 0.0464 | 0.4203 | 0.538 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0306 | 0.2357 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0556 | 0.5113 | 0.6451 |
Loa Loa (eye worm) | acyl carrier protein | 0.0056 | 0.0207 | 0.0234 |
Echinococcus granulosus | expressed conserved protein | 0.0096 | 0.0599 | 0.1931 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0071 | 0.0254 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.1003 | 0.9494 | 1 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0056 | 0.0207 | 0.0207 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.014 | 0.1025 | 1 |
Schistosoma mansoni | hypothetical protein | 0.032 | 0.2796 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0832 | 0.7812 | 1 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0464 | 0.4203 | 0.5255 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0843 | 0.7927 | 1 |
Echinococcus multilocularis | geminin | 0.0176 | 0.1384 | 0.1746 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0556 | 0.5113 | 0.6451 |
Mycobacterium ulcerans | acyl carrier protein | 0.0056 | 0.0207 | 0.0265 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0033 | 0.0319 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.032 | 0.2796 | 0.3165 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.014 | 0.1025 | 1 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0056 | 0.0207 | 0.2016 |
Echinococcus granulosus | AMP dependent ligase | 0.0057 | 0.0217 | 0.0698 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0448 | 0.4047 | 0.5049 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0591 | 0.5452 | 0.6897 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0063 | 0.0278 | 0.0093 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0044 | 0.0086 | 0.0098 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0396 | 0.354 | 0.6482 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0081 | 0.0449 | 0.6686 |
Echinococcus multilocularis | protein dispatched 1 | 0.005 | 0.0147 | 0.0186 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.014 | 0.1025 | 0.1877 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0102 | 0.066 | 0.0832 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0832 | 0.7812 | 1 |
Loa Loa (eye worm) | acyl carrier protein | 0.0256 | 0.2165 | 0.2451 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0539 | 0.4946 | 0.6231 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0038 | 0.0033 | 0.0033 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0044 | 0.0086 | 0.0109 |
Echinococcus granulosus | geminin | 0.0176 | 0.1384 | 0.4461 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0086 | 0.0098 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.014 | 0.1025 | 0.789 |
Echinococcus multilocularis | protein patched | 0.0044 | 0.0086 | 0.0109 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0148 | 0.0528 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0225 | 0.1862 | 0.2177 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0063 | 0.0278 | 0.0356 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0066 | 0.0306 | 0.2987 |
Schistosoma mansoni | patched 1 | 0.0044 | 0.0086 | 0.0309 |
Treponema pallidum | acyl carrier protein | 0.0056 | 0.0207 | 0.5 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0448 | 0.4047 | 0.518 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.2068 | 0.2341 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0905 | 0.0811 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0316 | 0.2758 | 0.3355 |
Mycobacterium ulcerans | fatty-acid-CoA ligase FadD9 | 0.0057 | 0.0217 | 0.0277 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0591 | 0.5452 | 0.6897 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0056 | 0.0207 | 0.0261 |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0056 | 0.0207 | 0.0234 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0591 | 0.5452 | 0.6897 |
Chlamydia trachomatis | acyl carrier protein | 0.0056 | 0.0207 | 0.2016 |
Loa Loa (eye worm) | fatty acid synthase | 0.0549 | 0.504 | 0.5706 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0063 | 0.0278 | 0.0093 |
Toxoplasma gondii | type I fatty acid synthase | 0.0085 | 0.0493 | 0.0902 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0056 | 0.0207 | 0.0261 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0168 | 0.13 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0905 | 0.0811 |
Brugia malayi | CHE-14 protein | 0.0044 | 0.0086 | 0.0086 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.014 | 0.1025 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0493 | 0.0558 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0033 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.2713 | 0.3071 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0464 | 0.4203 | 0.5255 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.014 | 0.1025 | 0.1312 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0071 | 0.0254 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0136 | 0.0989 | 0.1028 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0556 | 0.5113 | 0.6545 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0905 | 0.1025 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Onchocerca volvulus | 0.0527 | 0.4826 | 0.5005 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0282 | 0.2424 | 0.4437 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0148 | 0.0528 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0056 | 0.0207 | 0.2016 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0175 | 0.137 | 0.1529 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.04 | 0.3576 | 0.443 |
Mycobacterium ulcerans | hypothetical protein | 0.0056 | 0.0207 | 0.0265 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0085 | 0.0493 | 0.0376 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0056 | 0.0207 | 0.0207 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0063 | 0.0278 | 0.0278 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0038 | 0.0033 | 0.0106 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0038 | 0.0033 | 0.0252 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0592 | 0.5462 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.0167 | 0.1629 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0527 | 0.4826 | 0.6073 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0102 | 0.066 | 0.2127 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0023 | 0.0081 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0063 | 0.0278 | 0.0093 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0085 | 0.0493 | 0.0376 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0175 | 0.137 | 0.1529 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0057 | 0.0217 | 0.0277 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0071 | 0.0254 |
Plasmodium vivax | hypothetical protein, conserved | 0.008 | 0.0438 | 0.4269 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0448 | 0.4047 | 0.518 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0556 | 0.5113 | 0.6451 |
Leishmania major | acyl carrier protein, putative | 0.0056 | 0.0207 | 0.1591 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0168 | 0.13 | 0.1437 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.014 | 0.1025 | 0.1025 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0104 | 0.0675 | 0.2416 |
Echinococcus multilocularis | snurportin 1 | 0.032 | 0.2796 | 0.3526 |
Schistosoma mansoni | methyltransferase-related | 0.0168 | 0.13 | 0.4649 |
Onchocerca volvulus | 0.0051 | 0.016 | 0.0013 | |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0148 | 0.0148 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.1384 | 0.4951 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0591 | 0.5452 | 0.6979 |
Echinococcus granulosus | snurportin 1 | 0.032 | 0.2796 | 0.9011 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0168 | 0.13 | 0.13 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.014 | 0.1025 | 0.1293 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0171 | 0.1333 | 0.1481 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0038 | 0.0033 | 0.0117 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0246 | 0.2068 | 0.6665 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.008 | 0.0438 | 0.4269 |
Schistosoma mansoni | lipoxygenase | 0.0086 | 0.0497 | 0.1776 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0905 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.066 | 0.0747 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0038 | 0.0033 | 0.0117 |
Echinococcus multilocularis | AMP dependent ligase | 0.0057 | 0.0217 | 0.0273 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0063 | 0.0278 | 0.0356 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0368 | 0.3265 | 0.402 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0038 | 0.0033 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0207 | 0.074 |
Brugia malayi | RNA, U transporter 1 | 0.0085 | 0.0492 | 0.0492 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.014 | 0.1025 | 0.1161 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0023 | 0.0023 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0123 | 0.0859 | 0.2768 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0123 | 0.0859 | 0.1083 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0102 | 0.066 | 0.066 |
Onchocerca volvulus | 0.0063 | 0.0278 | 0.0139 | |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.014 | 0.1025 | 0.3305 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0306 | 0.2987 |
Brugia malayi | AMP-binding enzyme family protein | 0.0527 | 0.4826 | 0.4826 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0038 | 0.0033 | 0.0106 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.014 | 0.1025 | 0.1312 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0033 | 0.0319 |
Mycobacterium ulcerans | thioesterase | 0.0464 | 0.4203 | 0.538 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0171 | 0.1333 | 0.1707 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0556 | 0.5113 | 0.6451 |
Onchocerca volvulus | 0.0976 | 0.9226 | 0.9713 | |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0591 | 0.5452 | 0.6897 |
Plasmodium vivax | acyl carrier protein, putative | 0.0056 | 0.0207 | 0.2016 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0044 | 0.0086 | 0.0279 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.014 | 0.1025 | 0.3668 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0832 | 0.7812 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0556 | 0.5113 | 0.6451 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0038 | 0.0033 | 0.0106 |
Giardia lamblia | Methyltransferase like 2 | 0.0168 | 0.13 | 1 |
Schistosoma mansoni | acyl carrier protein | 0.0056 | 0.0207 | 0.074 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.014 | 0.1025 | 0.1312 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0539 | 0.4946 | 0.6231 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0306 | 0.2987 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0085 | 0.0493 | 0.0376 |
Mycobacterium tuberculosis | Conserved protein | 0.0168 | 0.13 | 0.1437 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0306 | 0.2357 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0023 | 0.0081 |
Onchocerca volvulus | Acyl carrier protein, mitochondrial homolog | 0.0056 | 0.0207 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0033 | 0.0037 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0056 | 0.0207 | 0.0666 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0063 | 0.0278 | 0.0356 |
Plasmodium falciparum | acyl carrier protein | 0.0056 | 0.0207 | 0.2016 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0056 | 0.0207 | 0.0379 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0038 | 0.0033 | 0.016 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.