Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0758 | 0.0758 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Mycobacterium leprae | putative cytochrome p450 | 0.0008 | 0.0375 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.1009 | 0.1019 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0023 | 0.1308 | 1 |
Trichomonas vaginalis | ankyrin 2,3/unc44, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0008 | 0.0375 | 0.2863 |
Trichomonas vaginalis | nf kappa B inhibitor I-kappa-B, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Plasmodium falciparum | protein kinase, putative | 0.0014 | 0.0758 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0758 | 0.0833 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Leishmania major | huntingtin interacting protein (HIP), putative | 0.0002 | 0.0014 | 0.0141 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0023 | 0.1308 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.1755 | 0.1773 |
Echinococcus granulosus | 26S proteasome non ATPase regulatory subunit 10 | 0.0002 | 0.0001 | 0.0001 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Giardia lamblia | Kinase, NEK | 0.0002 | 0.0014 | 1 |
Echinococcus granulosus | Sterile alpha motif SAM | 0.0014 | 0.0758 | 0.0759 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0023 | 0.1308 | 0.1437 |
Trichomonas vaginalis | ankyrin repeat and FYVE domain containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | ankyrin repeat and sam domain-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Echinococcus multilocularis | Ankyrin | 0.0002 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | toll and interleukin 1 receptor domain-containing protein isoform f | 0.0014 | 0.0758 | 0.0833 |
Trichomonas vaginalis | ankyrin repeat domain protein, putative | 0.0003 | 0.0038 | 0.0291 |
Trichomonas vaginalis | cortactin-binding protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | E3 ubiquitin protein ligase, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0008 | 0.0375 | 0.5 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0023 | 0.1308 | 1 |
Echinococcus multilocularis | liprin beta 1 | 0.0014 | 0.0758 | 0.0759 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Giardia lamblia | Kinase, NEK-frag | 0.0002 | 0.000000096934 | 0.0001 |
Giardia lamblia | Kinase, NEK | 0.0002 | 0.0014 | 1 |
Trichomonas vaginalis | ion channel nompc, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Brugia malayi | Neurabin protein 1 | 0.0014 | 0.0758 | 0.0766 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0008 | 0.0375 | 0.5 |
Schistosoma mansoni | lip-related protein (liprin) alpha | 0.0014 | 0.0758 | 0.0758 |
Trichomonas vaginalis | ion channel nompc, putative | 0.0002 | 0.0014 | 0.0109 |
Echinococcus granulosus | Ankyrin | 0.0002 | 0.0014 | 0.0014 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | protein phosphatase 1 regulatory subunit 12B, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0008 | 0.0375 | 0.5 |
Schistosoma mansoni | lar interacting protein (lip)-related protein | 0.0014 | 0.0758 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0002 | 0.000000096934 | 0.00000010649 |
Echinococcus multilocularis | Ankyrin | 0.0002 | 0.000000096934 | 0.000000097072 |
Echinococcus granulosus | liprin alpha 2 | 0.0014 | 0.0758 | 0.0759 |
Brugia malayi | Liprin-alpha 2 | 0.0014 | 0.0758 | 0.0766 |
Schistosoma mansoni | 26S proteasome subunit | 0.0002 | 0.000000096934 | 0.000000096934 |
Brugia malayi | coiled-coil like protein 1 | 0.0014 | 0.0758 | 0.0766 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Brugia malayi | Patatin-like phospholipase family protein | 0.0002 | 0.000000096934 | 0.000000097923 |
Loa Loa (eye worm) | cytochrome P450 | 0.0008 | 0.0375 | 0.0411 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Echinococcus multilocularis | E3 ubiquitin protein ligase mib1 | 0.0002 | 0.0014 | 0.0014 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0496 | 0.0545 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0758 | 0.0758 |
Schistosoma mansoni | cytochrome P450 | 0.0008 | 0.0375 | 0.0375 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0008 | 0.0375 | 0.3714 |
Trichomonas vaginalis | 2-5A-dependent ribonuclease, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | fetal globin-inducing factor, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Giardia lamblia | Kinase, NEK | 0.0002 | 0.000000096934 | 0.0001 |
Trypanosoma cruzi | palmitoyl acyltransferase 1, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0016 | 0.012 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.1308 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | ankyrin, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0023 | 0.1308 | 0.131 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Echinococcus granulosus | tankyrase | 0.0159 | 0.9986 | 1 |
Trichomonas vaginalis | ankyrin, putative | 0.0002 | 0.0001 | 0.0011 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.1755 | 0.1928 |
Loa Loa (eye worm) | tnks protein | 0.0145 | 0.9103 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0758 | 0.5796 |
Entamoeba histolytica | ankyrin repeat protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | multiple ankyrin repeats single kh domain protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0023 | 0.1308 | 0.131 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0023 | 0.1308 | 0.131 |
Brugia malayi | Tnks protein | 0.0158 | 0.9899 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0018 | 0.1009 | 0.1108 |
Onchocerca volvulus | Tankyrase homolog | 0.0143 | 0.8951 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.1009 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1308 | 0.1437 |
Schistosoma mansoni | sarm1 | 0.0014 | 0.0758 | 0.0758 |
Trichomonas vaginalis | ankyrin, putative | 0.0002 | 0.0014 | 0.0109 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | 26S proteasome non-ATPase regulatory subunit, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Brugia malayi | cytochrome P450 | 0.0008 | 0.0375 | 0.0378 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | homeobox-containing protein wariai, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0008 | 0.0375 | 0.2863 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0758 | 0.5796 |
Echinococcus multilocularis | stromal interaction molecule 1 | 0.0014 | 0.0758 | 0.0759 |
Echinococcus granulosus | liprin beta 1 | 0.0014 | 0.0758 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.7519 | 0.826 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | unc-44 ankyrins, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Echinococcus granulosus | SAM domain containing protein | 0.0014 | 0.0758 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0758 | 0.0833 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0018 | 0.1009 | 0.1108 |
Brugia malayi | WGR domain containing protein | 0.0023 | 0.1308 | 0.1322 |
Trichomonas vaginalis | ankyrin repeat-rich membrane-spanning protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trypanosoma brucei | Ankyrin repeats (many copies), putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0018 | 0.1009 | 0.1108 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0758 | 0.5796 |
Trichomonas vaginalis | rolling pebbles, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat domain protein, putative | 0.0002 | 0.0014 | 0.0109 |
Brugia malayi | WGR domain containing protein | 0.0023 | 0.1308 | 0.1322 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trypanosoma brucei | cytochrome P450, putative | 0.0018 | 0.1009 | 0.7708 |
Loa Loa (eye worm) | hypothetical protein | 0.0002 | 0.000000096934 | 0.00000010649 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Onchocerca volvulus | 0.0014 | 0.0758 | 0.0847 | |
Echinococcus multilocularis | ankyrin repeat domain containing protein 6 | 0.0002 | 0.000000096934 | 0.000000097072 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Toxoplasma gondii | Tyrosine kinase-like (TKL) protein | 0.0014 | 0.0758 | 0.5796 |
Trichomonas vaginalis | ion channel nompc, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | ankyrin repeat-rich membrane-spanning protein, putative | 0.0002 | 0.0001 | 0.0011 |
Brugia malayi | Patatin-like phospholipase family protein | 0.0002 | 0.0014 | 0.0014 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0018 | 0.1009 | 0.7708 |
Schistosoma mansoni | phospholipase | 0.0002 | 0.000000096934 | 0.000000096934 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | protein phosphatase 1 regulatory subunit 12B, putative | 0.0002 | 0.0001 | 0.0011 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | unc-44 ankyrins, putative | 0.0002 | 0.0014 | 0.0109 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0008 | 0.0375 | 0.2863 |
Onchocerca volvulus | 0.0014 | 0.0758 | 0.0847 | |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0008 | 0.0375 | 0.2863 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Brugia malayi | Leucine Rich Repeat family protein | 0.0002 | 0.000000096934 | 0.000000097923 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Echinococcus multilocularis | liprin alpha 2 | 0.0014 | 0.0758 | 0.0759 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0758 | 0.0833 |
Trichomonas vaginalis | 2-5A-dependent ribonuclease, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | unc-44 ankyrins, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0008 | 0.0375 | 0.5 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0758 | 0.0766 |
Trichomonas vaginalis | serine/threonine-protein kinase ripk4, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | ankyrin repeat domain protein, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | sex-determining protein fem-1, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat domain-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Giardia lamblia | Kinase, NEK | 0.0002 | 0.000000096934 | 0.0001 |
Schistosoma mansoni | ga binding protein beta chain (transcription factor e4tf1-47) | 0.0002 | 0.000000096934 | 0.000000096934 |
Trichomonas vaginalis | ankyrin 2,3/unc44, putative | 0.0002 | 0.0014 | 0.0109 |
Echinococcus granulosus | stromal interaction molecule 1 | 0.0014 | 0.0758 | 0.0759 |
Brugia malayi | Cytochrome P450 family protein | 0.0008 | 0.0375 | 0.0378 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Brugia malayi | Uncoordinated protein 44 | 0.0002 | 0.0001 | 0.0002 |
Trichomonas vaginalis | mind bomb, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Entamoeba histolytica | zinc finger protein, putative | 0.0023 | 0.1308 | 1 |
Echinococcus multilocularis | SAM domain containing protein | 0.0014 | 0.0758 | 0.0759 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0008 | 0.0375 | 0.2863 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0023 | 0.1308 | 0.1308 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0008 | 0.0375 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Giardia lamblia | Protein 21.1 | 0.0002 | 0.000000096934 | 0.0001 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0023 | 0.1308 | 0.131 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0003 | 0.004 | 0.0303 |
Loa Loa (eye worm) | Notch2 | 0.0002 | 0.0001 | 0.0002 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0018 | 0.1009 | 1 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0008 | 0.0375 | 0.0375 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0008 | 0.0375 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.1308 | 1 |
Echinococcus multilocularis | 0.0008 | 0.0375 | 0.0375 | |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | ankyrin, putative | 0.0002 | 0.0001 | 0.0011 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | 2-5A-dependent ribonuclease, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0023 | 0.1308 | 1 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | ankyrin, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trypanosoma brucei | palmitoyl acyltransferase 1, putative | 0.0002 | 0.0014 | 0.0109 |
Echinococcus multilocularis | 26S proteasome non ATPase regulatory subunit 10 | 0.0002 | 0.0001 | 0.0001 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0023 | 0.1308 | 1 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0023 | 0.1308 | 0.1308 |
Echinococcus multilocularis | poly (ADP ribose) polymerase | 0.0023 | 0.1308 | 0.131 |
Trichomonas vaginalis | protein phosphatase 1 regulatory subunit 12C, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | c2h2 zinc finger protein, putative | 0.0014 | 0.0758 | 0.5796 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0002 | 0.0014 | 0.0014 |
Trypanosoma cruzi | palmitoyl acyltransferase 1, putative | 0.0002 | 0.0014 | 0.0109 |
Trichomonas vaginalis | ankyrin repeat domain protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | tankyrase, putative | 0.0002 | 0.0001 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0002 | 0.0016 | 0.0017 |
Trichomonas vaginalis | fibronectin type 3 and ankyrin repeat domains, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Echinococcus multilocularis | sterile alpha and tir motif containing protein | 0.0014 | 0.0758 | 0.0759 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.1308 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0008 | 0.0375 | 0.5 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Echinococcus granulosus | E3 ubiquitin protein ligase mib1 | 0.0002 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0002 | 0.000000096934 | 0.00000010649 |
Leishmania major | cytochrome p450-like protein | 0.0008 | 0.0375 | 0.3714 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0001 | 0.0011 |
Echinococcus granulosus | sterile alpha and tir motif containing protein | 0.0014 | 0.0758 | 0.0759 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0758 | 0.0766 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0758 | 0.0758 |
Trichomonas vaginalis | ion channel nompc, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | multiple ankyrin repeats single kh domain protein, putative | 0.0002 | 0.0014 | 0.0109 |
Plasmodium falciparum | tyrosine kinase-like protein | 0.0014 | 0.0758 | 0.5 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0008 | 0.0375 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.1009 | 1 |
Giardia lamblia | Protein 21.1 | 0.0002 | 0.000000096934 | 0.0001 |
Plasmodium vivax | tyrosine kinase-like protein, putative | 0.0014 | 0.0758 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | ankyrin repeat and FYVE domain containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0008 | 0.0375 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0758 | 0.0758 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0008 | 0.0375 | 0.5 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0758 | 0.0833 |
Brugia malayi | sterile alpha and TIR motif containing protein 1 isoform a | 0.0014 | 0.0758 | 0.0766 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trichomonas vaginalis | cask-interacting protein (caskin) 1,2, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Leishmania major | cytochrome p450-like protein | 0.0008 | 0.0375 | 0.3714 |
Trichomonas vaginalis | ankyrin 2,3/unc44, putative | 0.0003 | 0.0054 | 0.0411 |
Trichomonas vaginalis | ion channel nompc, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Trypanosoma cruzi | ankyrin repeat protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0758 | 0.0833 |
Echinococcus granulosus | Ankyrin | 0.0002 | 0.000000096934 | 0.000000097072 |
Schistosoma mansoni | hypothetical protein | 0.0008 | 0.0375 | 0.0375 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.000000096934 | 0.0000007409 |
Loa Loa (eye worm) | hypothetical protein | 0.0002 | 0.000000096934 | 0.00000010649 |
Giardia lamblia | Ankyrin 1 | 0.0002 | 0.000000096934 | 0.0001 |
Trichomonas vaginalis | ankyrin repeat domain protein, putative | 0.0002 | 0.0001 | 0.0011 |
Echinococcus multilocularis | tankyrase | 0.0159 | 0.9986 | 1 |
Trichomonas vaginalis | inversin, putative | 0.0002 | 0.0001 | 0.0011 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0002 | 0.0014 | 0.0109 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.1308 | 1 |
Trichomonas vaginalis | ankyrin, putative | 0.0002 | 0.0016 | 0.012 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0018 | 0.1009 | 0.7708 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.1308 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.0758 | 0.5796 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.713 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.617 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.5 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.297 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.286 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.048 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.931 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.908 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.841 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.837 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.815 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.