TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 331.436 | Formula: C16H21N5OS
H donors: 3 H acceptors: 1 LogP: 1.73 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: S=C(Nc1ccc2c(c1)OCCN2)NCCCn1cncc1C
InChi: 1S/C16H21N5OS/c1-12-10-17-11-21(12)7-2-5-19-16(23)20-13-3-4-14-15(9-13)22-8-6-18-14/h3-4,9-11,18H,2,5-8H2,1H3,(H2,19,20,23)
InChiKey: JNEFRFOQBZMTIU-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	glutaminyl-peptide cyclotransferase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Echinococcus multilocularis	glutaminyl peptide cyclotransferase	Get druggable targets OG5_129821	All targets in OG5_129821
Echinococcus granulosus	glutaminyl peptide cyclotransferase	Get druggable targets OG5_129821	All targets in OG5_129821
Brugia malayi	Peptidase family M28 containing protein	Get druggable targets OG5_129821	All targets in OG5_129821
Schistosoma japonicum	ko:K00683 glutaminyl-peptide cyclotransferase [EC2.3.2.5], putative	Get druggable targets OG5_129821	All targets in OG5_129821
Onchocerca volvulus	Glutaminyl cyclase homolog	Get druggable targets OG5_129821	All targets in OG5_129821
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_129821	All targets in OG5_129821
Schistosoma mansoni	glutaminyl cyclase (M28 family)	Get druggable targets OG5_129821	All targets in OG5_129821

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Echinococcus granulosus	endoplasmic reticulum metallopeptidase 1	glutaminyl-peptide cyclotransferase	361 aa	292 aa	21.9 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsB	0.0021	0.1044	0.4188
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0011	0.0223	0.0223
Brugia malayi	ecdysteroid receptor	0.0011	0.0223	0.0223
Leishmania major	4-coumarate:coa ligase-like protein	0.0026	0.1365	1
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC	0.0028	0.1578	0.6337
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0011	0.0223	0.0223
Mycobacterium ulcerans	multifunctional mycocerosic acid synthase membrane-associated Mas	0.0028	0.1578	0.6357
Echinococcus granulosus	endoplasmic reticulum metallopeptidase 1	0.0022	0.1066	0.0862
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0026	0.1365	0.5467
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0011	0.0223	0.0223
Echinococcus multilocularis	endoplasmic reticulum metallopeptidase 1	0.0022	0.1066	0.0862
Onchocerca volvulus	Fxna peptidase homolog	0.0022	0.1066	0.0912
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0011	0.0223	0.0223
Toxoplasma gondii	hypothetical protein	0.0022	0.1066	0.4859
Mycobacterium tuberculosis	Probable peptide synthetase Nrp (peptide synthase)	0.001	0.0169	0.0683
Mycobacterium ulcerans	non-ribosomal peptide synthetase MbtF	0.001	0.0169	0.0634
Mycobacterium tuberculosis	Phenolpthiocerol synthesis type-I polyketide synthase PpsD	0.0027	0.1449	0.5856
Onchocerca volvulus	Protein ultraspiracle homolog	0.0011	0.0223	0.0055
Loa Loa (eye worm)	hypothetical protein	0.0022	0.1066	0.0862
Mycobacterium ulcerans	thioesterase TesA	0.0022	0.1104	0.443
Mycobacterium leprae	PROBABLE THIOESTERASE TESA	0.0022	0.1104	0.4398
Mycobacterium tuberculosis	Probable polyketide synthase Pks15	0.0011	0.0214	0.0864
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0862	0.0653
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0011	0.0223	0.0223
Echinococcus multilocularis	endoplasmic reticulum metallopeptidase 1	0.0022	0.1066	0.0862
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0011	0.0223	0.0055
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsC	0.0028	0.1578	0.6357
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0019	0.0862	0.3449
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.001	0.0169	0.0169
Schistosoma mansoni	nicalin (M28 family)	0.0022	0.1066	0.1066
Mycobacterium ulcerans	polyketide synthase Pks13	0.004	0.2475	1
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0026	0.1365	0.5492
Toxoplasma gondii	beta-ketoacyl synthase, N-terminal domain-containing protein	0.0017	0.0721	0.1871
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsE	0.0018	0.0747	0.2981
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0011	0.0223	0.0223
Trypanosoma brucei	glutaminyl cyclase, putative	0.0022	0.1066	0.5
Mycobacterium tuberculosis	Probable membrane bound polyketide synthase Pks6	0.004	0.2475	1
Mycobacterium tuberculosis	Conserved protein	0.0022	0.1066	0.4306
Brugia malayi	nuclear receptor NHR-88	0.0011	0.0223	0.0223
Leishmania major	4-coumarate:coa ligase-like protein	0.0026	0.1365	1
Trypanosoma cruzi	glutaminyl cyclase, putative	0.0022	0.1066	0.5
Loa Loa (eye worm)	acyl carrier protein	0.0012	0.0329	0.0108
Mycobacterium tuberculosis	Polyketide synthetase MbtD (polyketide synthase)	0.0008	0.0013	0.0052
Mycobacterium tuberculosis	Phenolpthiocerol synthesis type-I polyketide synthase PpsA	0.0027	0.1449	0.5856
Brugia malayi	leucyl aminopeptidase	0.0022	0.1066	0.1066
Mycobacterium tuberculosis	Phenyloxazoline synthase MbtB (phenyloxazoline synthetase)	0.0032	0.1897	0.7666
Leishmania major	glutaminyl cyclase, putative	0.0022	0.1066	0.7807
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.0032	0.1897	0.1712
Echinococcus multilocularis	glutaminyl peptide cyclotransferase	0.0136	1	1
Toxoplasma gondii	type I fatty acid synthase, putative	0.0019	0.0852	0.3005
Giardia lamblia	Methyltransferase like 2	0.0008	0	0.5
Brugia malayi	photoreceptor-specific nuclear receptor	0.0011	0.0223	0.0223
Plasmodium vivax	acyl-CoA synthetase, putative	0.0019	0.0862	0.5
Mycobacterium ulcerans	hypothetical protein	0.0026	0.1365	0.5492
Mycobacterium leprae	Probable polyketide synthase Pks1	0.0028	0.1578	0.6337
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE	0.0018	0.0747	0.2941
Mycobacterium tuberculosis	Probable polyketide synthase Pks1	0.0019	0.0865	0.3495
Mycobacterium tuberculosis	Probable lipoprotein aminopeptidase LpqL	0.0022	0.1066	0.4306
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0011	0.0223	0.0223
Mycobacterium ulcerans	Type I modular polyketide synthase	0.0027	0.1449	0.5834
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0011	0.0223	0.0223
Toxoplasma gondii	type I fatty acid synthase, putative	0.0029	0.166	1
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0011	0.0223	0.0223
Loa Loa (eye worm)	hypothetical protein	0.0136	1	1
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0862	0.0653
Onchocerca volvulus		0.0026	0.1365	0.1217
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.1066	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0026	0.1365	0.5516
Loa Loa (eye worm)	hypothetical protein	0.0026	0.1365	0.1168
Brugia malayi	steroid hormone receptor	0.0011	0.0223	0.0223
Schistosoma mansoni	glutaminyl-peptide cyclotransferase-related	0.0022	0.1066	0.1066
Mycobacterium ulcerans	non-ribosomal peptide synthetase MbtE	0.001	0.0169	0.0634
Onchocerca volvulus	Bile acid receptor homolog	0.0011	0.0223	0.0055
Brugia malayi	AMP-binding enzyme family protein	0.0026	0.1365	0.1365
Mycobacterium ulcerans	thioesterase	0.0022	0.1104	0.443
Loa Loa (eye worm)	leucyl aminopeptidase	0.0022	0.1066	0.0862
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0011	0.0223	0.0223
Mycobacterium leprae	Polyketide synthase Pks13	0.004	0.2475	1
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0026	0.1365	0.5516
Mycobacterium tuberculosis	Polyketide synthase Pks12	0.0028	0.1578	0.6376
Onchocerca volvulus	Fatty acid synthase homolog	0.0048	0.3114	0.2996
Onchocerca volvulus		0.0054	0.357	0.3459
Onchocerca volvulus		0.0011	0.0223	0.0055
Schistosoma mansoni	glutaminyl cyclase (M28 family)	0.0136	1	1
Mycobacterium ulcerans	lipoprotein aminopeptidase LpqL	0.0022	0.1066	0.4276
Brugia malayi	AMP-binding enzyme family protein	0.0032	0.1897	0.1897
Mycobacterium tuberculosis	Polyketide synthetase MbtC (polyketide synthase)	0.0009	0.0088	0.0356
Mycobacterium leprae	Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas	0.0028	0.1578	0.6337
Mycobacterium tuberculosis	Polyketide synthase Pks2	0.0026	0.1386	0.5599
Onchocerca volvulus	Fxna peptidase homolog	0.0022	0.1066	0.0912
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0011	0.0223	0.0223
Brugia malayi	oxidoreductase, zinc-binding dehydrogenase family protein	0.0051	0.3307	0.3307
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0537	0.0321
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0011	0.0223	0.0223
Loa Loa (eye worm)	hypothetical protein	0.0046	0.2941	0.278
Mycobacterium ulcerans	acyl-CoA synthetase	0.001	0.0169	0.0634
Mycobacterium tuberculosis	Probable polyketide synthase Pks5	0.0026	0.1386	0.5599
Mycobacterium ulcerans	polyketide synthase	0.0027	0.1449	0.5834
Loa Loa (eye worm)	hypothetical protein	0.0022	0.1066	0.0862
Brugia malayi	AMP-binding enzyme family protein	0.0026	0.1365	0.1365
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.1066	1
Mycobacterium ulcerans	acyl-CoA synthetase	0.0026	0.1365	0.5492
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0781	0.3155
Mycobacterium tuberculosis	Peptide synthetase MbtE (peptide synthase)	0.001	0.0169	0.0683
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0781	0.3155
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.1066	1
Trypanosoma cruzi	glutaminyl cyclase, putative	0.0022	0.1066	0.5
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0019	0.0862	0.5
Schistosoma mansoni	thyroid hormone receptor	0.0011	0.0223	0.0223
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0011	0.0223	0.0223
Loa Loa (eye worm)	hypothetical protein	0.0022	0.1066	0.0862
Loa Loa (eye worm)	hypothetical protein	0.0022	0.1066	0.0862
Mycobacterium ulcerans	polyketide synthase Pks9	0.0018	0.0747	0.2981
Leishmania major	4-coumarate:coa ligase-like protein	0.0026	0.1365	1
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0026	0.1365	0.5492
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0862	0.0653
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0011	0.0223	0.0223
Mycobacterium tuberculosis	Peptide synthetase MbtF (peptide synthase)	0.001	0.0169	0.0683
Brugia malayi	nuclear hormone receptor	0.0011	0.0223	0.0223
Mycobacterium ulcerans	acyl-CoA synthetase	0.0026	0.1365	0.5492
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0862	0.0653
Echinococcus multilocularis	n acetylated alpha linked acidic dipeptidase 2	0.0022	0.1066	0.0862
Mycobacterium ulcerans	Type I modular polyketide synthase	0.0027	0.1449	0.5834
Brugia malayi	Steroid receptor seven-up type 2	0.0011	0.0223	0.0223
Schistosoma mansoni	RAR-like nuclear receptor	0.0011	0.0223	0.0223
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD	0.0027	0.1449	0.581
Leishmania major	hypothetical protein, conserved	0.0022	0.1066	0.7807
Onchocerca volvulus		0.0032	0.1897	0.1758
Echinococcus granulosus	glutaminyl peptide cyclotransferase	0.0136	1	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0781	0.3155
Mycobacterium tuberculosis	Probable thioesterase TesA	0.0022	0.1104	0.4459
Mycobacterium ulcerans	fatty acid synthase Fas	0.0008	0.0027	0.0056
Mycobacterium ulcerans	phenyloxazoline synthase MbtB	0.001	0.0169	0.0634
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0028	0.1575	1
Trichomonas vaginalis	Clan MH, family M28, aminopeptidase S-like metallopeptidase	0.0022	0.1066	1
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0019	0.0862	0.3483
Brugia malayi	Beta-ketoacyl synthase, N-terminal domain containing protein	0.0027	0.1449	0.1449
Plasmodium falciparum	acyl-CoA synthetase	0.0019	0.0862	0.5
Mycobacterium tuberculosis	Phenolpthiocerol synthesis type-I polyketide synthase PpsC	0.0027	0.1449	0.5856
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0011	0.0223	0.0223
Loa Loa (eye worm)	hypothetical protein	0.0026	0.1365	0.1168
Schistosoma mansoni	nuclear hormone receptor	0.0011	0.0223	0.0223
Mycobacterium tuberculosis	Polyketide synthase Pks13	0.004	0.2475	1
Toxoplasma gondii	peptidase, M28 family protein	0.0022	0.1066	0.4859
Mycobacterium leprae	Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase)	0.001	0.0169	0.0581
Mycobacterium tuberculosis	Probable fatty acid synthase Fas (fatty acid synthetase)	0.0008	0.0027	0.0108
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0011	0.0223	0.0223
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0011	0.0223	0.0223
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0026	0.1365	0.5467
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0011	0.0223	0.0223
Onchocerca volvulus		0.0022	0.1066	0.0912
Mycobacterium ulcerans	polyketide synthase	0.0028	0.1578	0.6357
Mycobacterium ulcerans	peptide synthetase Nrp (peptide synthase)	0.001	0.0169	0.0634
Onchocerca volvulus	Fxna peptidase homolog	0.0022	0.1066	0.0912
Mycobacterium ulcerans	Type I modular polyketide synthase	0.0027	0.1449	0.5834
Mycobacterium ulcerans	acyl-CoA synthetase	0.0026	0.1365	0.5492
Schistosoma mansoni	Fxna peptidase (M28 family)	0.0022	0.1066	0.1066
Mycobacterium tuberculosis	Probable polyketide synthase Pks8	0.0022	0.1071	0.4329
Mycobacterium tuberculosis	Probable multifunctional mycocerosic acid synthase membrane-associated Mas	0.0028	0.1578	0.6376
Echinococcus granulosus	endoplasmic reticulum metallopeptidase 1	0.0022	0.1066	0.0862
Schistosoma mansoni	thyroid hormone receptor	0.0011	0.0223	0.0223
Loa Loa (eye worm)	hypothetical protein	0.0026	0.1365	0.1168
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0026	0.1365	0.5492
Mycobacterium ulcerans	hypothetical protein	0.0022	0.1066	0.4276
Schistosoma mansoni	NAALADASE L peptidase (M28 family)	0.0022	0.1066	0.1066
Schistosoma mansoni	coup transcription factor	0.0011	0.0223	0.0223
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0026	0.1365	0.5492
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0011	0.0223	0.0223
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsD	0.0027	0.1449	0.5834
Mycobacterium tuberculosis	P-hydroxybenzoyl-AMP ligase FadD22	0.001	0.0169	0.0683
Brugia malayi	Nuclear hormone receptor-like 1	0.0011	0.0223	0.0223
Schistosoma mansoni	retinoic acid receptor RXR	0.0011	0.0223	0.0223
Brugia malayi	AMP-binding enzyme family protein	0.0026	0.1365	0.1365
Brugia malayi	FXNA	0.0022	0.1066	0.1066
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA	0.0027	0.1449	0.581
Onchocerca volvulus	Glutaminyl cyclase homolog	0.0136	1	1
Brugia malayi	AMP-binding enzyme family protein	0.0009	0.0094	0.0094
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsA	0.0021	0.1044	0.4188
Loa Loa (eye worm)	fatty acid synthase	0.0026	0.1422	0.1226
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0018	0.0781	0.3155
Mycobacterium tuberculosis	Probable polyketide synthase Pks7	0.0028	0.1578	0.6376
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB	0.0021	0.1044	0.4155
Mycobacterium tuberculosis	Probable polyketide synthase Pks9	0.0015	0.0554	0.224
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0862	0.0653
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0011	0.0223	0.0223
Brugia malayi	nicalin	0.0022	0.1066	0.1066

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 1070 nM	Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analysis	ChEMBL.	23643900

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2392816

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1778041