Detailed information for compound 1807055

Basic information

Technical information
  • TDR Targets ID: 1807055
  • Name: Phenyl N,N-dimethylcarbamate
  • MW: 165.189 | Formula: C9H11NO2
  • H donors: 0 H acceptors: 1 LogP: 1.69 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C(=O)Oc1ccccc1)C
  • InChi: 1S/C9H11NO2/c1-10(2)9(11)12-8-6-4-3-5-7-8/h3-7H,1-2H3
  • InChiKey: MYOHNZJKOAODMX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N,N-dimethylcarbamic acid phenyl ester
  • 6658-63-5
  • 6969-90-0
  • NSC79876
  • Carbamic acid, dimethyl-, phenyl ester
  • NSC68654
  • Phenyl dimethylcarbamate
  • WLN: 1N1&VOR
  • Phenyl-n,n-dimethyl carbamate
  • FA2982500
  • TL-1113
  • NCIOpen2_000405
  • NCIOpen2_000830

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Tubulin alpha-2 chain 0.0403 0.5079 0.5079
Trypanosoma brucei zeta tubulin 0.0134 0.1591 0.1961
Mycobacterium ulcerans glutaminase 0.0256 0.3175 1
Trichomonas vaginalis conserved hypothetical protein 0.0134 0.1591 0.1961
Loa Loa (eye worm) alpha-tubulin 0.0403 0.5079 0.5065
Schistosoma mansoni tubulin subunit epsilon 0.0308 0.3854 0.3837
Echinococcus multilocularis tubulin alpha 3 chain 0.0403 0.5079 0.5065
Echinococcus multilocularis beta tubulin 0.062 0.7896 0.789
Trypanosoma brucei beta tubulin 0.062 0.7896 1
Brugia malayi Thioredoxin reductase 0.0044 0.0428 0.0428
Trypanosoma brucei beta tubulin 0.062 0.7896 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.016 0.0137
Echinococcus multilocularis tubulin epsilon chain 0.0308 0.3854 0.3837
Trichomonas vaginalis tubulin beta chain, putative 0.0403 0.5079 0.6408
Leishmania major beta tubulin 0.062 0.7896 1
Loa Loa (eye worm) tubulin beta chain 0.062 0.7896 0.789
Echinococcus granulosus tubulin alpha chain 0.0403 0.5079 0.5065
Schistosoma mansoni tyrosine kinase 0.0467 0.5904 0.5892
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.016 0.0137
Plasmodium falciparum alpha tubulin 1 0.0403 0.5079 0.6408
Plasmodium vivax tubulin alpha chain, putative 0.0403 0.5079 0.6408
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Trichomonas vaginalis tubulin alpha chain, putative 0.062 0.7896 1
Trichomonas vaginalis tubulin beta chain, putative 0.0403 0.5079 0.6408
Loa Loa (eye worm) hypothetical protein 0.0403 0.5079 0.5065
Mycobacterium tuberculosis Probable dehydrogenase 0.0101 0.1164 0.7226
Leishmania major beta tubulin 0.062 0.7896 1
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0023 0.0147 0.012
Leishmania major beta tubulin 0.062 0.7896 1
Echinococcus multilocularis hypothetical protein 0.0403 0.5079 0.5065
Trypanosoma cruzi zeta tubulin, putative 0.0134 0.1591 0.1961
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0248 0.3072 0.3051
Echinococcus granulosus tubulin gamma 1 chain 0.0308 0.3854 0.3837
Trypanosoma cruzi beta tubulin, putative 0.062 0.7896 1
Trichomonas vaginalis tubulin, putative 0.0175 0.2117 0.2632
Plasmodium vivax tubulin alpha chain, putative 0.0403 0.5079 0.6408
Loa Loa (eye worm) BEN-1 protein 0.062 0.7896 0.789
Trypanosoma brucei beta tubulin 0.0308 0.3854 0.4847
Loa Loa (eye worm) alpha-tubulin 0.0403 0.5079 0.5065
Echinococcus granulosus tubulin beta 4A class IVa 0.062 0.7896 0.789
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Echinococcus granulosus tubulin alpha chain 0.0403 0.5079 0.5065
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0246 0.0218
Brugia malayi tubulin alpha chain - mouse 0.0403 0.5079 0.5079
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0175 0.2117 0.2632
Brugia malayi CXXC zinc finger family protein 0.003 0.0246 0.0246
Echinococcus granulosus Tubulin alpha 1 chain 0.0403 0.5079 0.5065
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0015 0.0053 0.0024
Trichomonas vaginalis tubulin gamma chain, putative 0.0308 0.3854 0.4847
Echinococcus multilocularis Tubulin beta 2C chain 0.062 0.7896 0.789
Trypanosoma cruzi zeta tubulin, putative 0.0134 0.1591 0.1961
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0015 0.0053 0.0024
Echinococcus multilocularis tubulin alpha 1C chain 0.0403 0.5079 0.5065
Echinococcus multilocularis Tubulin beta 2C chain 0.062 0.7896 0.789
Echinococcus multilocularis cpg binding protein 0.0032 0.0269 0.024
Giardia lamblia Alpha-tubulin 0.0403 0.5079 0.6408
Mycobacterium leprae cell division protein FtsZ 0.0134 0.1591 1
Loa Loa (eye worm) thioredoxin reductase 0.0044 0.0428 0.04
Loa Loa (eye worm) tubulin alpha 2 0.0094 0.1078 0.1052
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.5442 0.5429
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0112 0.131 0.3427
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Schistosoma mansoni tyrosine kinase 0.0248 0.3072 0.3051
Echinococcus granulosus epidermal growth factor receptor 0.0471 0.5966 0.5954
Echinococcus granulosus Tubulin beta 2C chain 0.062 0.7896 0.789
Echinococcus multilocularis beta tubulin 0.062 0.7896 0.789
Schistosoma mansoni hypothetical protein 0.0431 0.5442 0.5429
Loa Loa (eye worm) tubulin alpha chain 0.0403 0.5079 0.5065
Echinococcus granulosus adhesion regulating molecule 1 0.0043 0.0417 0.0389
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Schistosoma mansoni tubulin subunit beta 0.062 0.7896 0.789
Treponema pallidum cell division protein FtsZ 0.0134 0.1591 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0403 0.5079 0.6408
Trichomonas vaginalis tubulin beta chain, putative 0.0403 0.5079 0.6408
Toxoplasma gondii beta tubulin 0.062 0.7896 1
Plasmodium vivax thioredoxin reductase, putative 0.0044 0.0428 0.0479
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0044 0.0428 0.2441
Loa Loa (eye worm) tubulin alpha-2 chain 0.0403 0.5079 0.5065
Echinococcus multilocularis Tubulin beta 2C chain 0.062 0.7896 0.789
Leishmania major beta tubulin 0.062 0.7896 1
Plasmodium falciparum alpha tubulin 2 0.0403 0.5079 0.6408
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0134 0.1591 1
Trypanosoma brucei zeta tubulin, putative 0.0134 0.1591 0.1961
Echinococcus multilocularis Tubulin alpha 1 chain 0.0403 0.5079 0.5065
Trichomonas vaginalis tubulin, putative 0.0175 0.2117 0.2632
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0018 0.009 0.0062
Schistosoma mansoni hypothetical protein 0.0179 0.2169 0.2146
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0134 0.1591 0.1961
Echinococcus granulosus Tubulin beta 2C chain 0.062 0.7896 0.789
Loa Loa (eye worm) BEN-1 protein 0.062 0.7896 0.789
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.016 0.0137
Echinococcus granulosus peroxisome assembly protein 26 0.0403 0.5079 0.5065
Trichomonas vaginalis tubulin beta chain, putative 0.0403 0.5079 0.6408
Echinococcus granulosus tubulin alpha 3 chain 0.0403 0.5079 0.5065
Toxoplasma gondii alpha-tubulin I, putative 0.0403 0.5079 0.6408
Trichomonas vaginalis tubulin alpha chain, putative 0.0175 0.2117 0.2632
Echinococcus granulosus beta tubulin 0.062 0.7896 0.789
Schistosoma mansoni tubulin subunit beta 0.062 0.7896 0.789
Echinococcus granulosus Tubulin alpha 1 chain 0.0403 0.5079 0.5065
Plasmodium falciparum tubulin beta chain 0.062 0.7896 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.016 0.0131
Schistosoma mansoni alpha tubulin 0.0403 0.5079 0.5065
Leishmania major hypothetical protein, conserved 0.0024 0.016 0.0137
Echinococcus multilocularis tubulin alpha 0.0308 0.3854 0.3837
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Schistosoma mansoni cpg binding protein 0.0032 0.0269 0.024
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0403 0.5079 0.6408
Echinococcus granulosus tubulin alpha chain 0.0403 0.5079 0.5065
Trichomonas vaginalis tubulin beta chain, putative 0.0403 0.5079 0.6408
Echinococcus multilocularis epidermal growth factor receptor 0.0471 0.5966 0.5954
Trypanosoma brucei alpha tubulin 0.0403 0.5079 0.6408
Echinococcus multilocularis tubulin alpha chain 0.0403 0.5079 0.5065
Brugia malayi Tubulin beta-1 chain 0.062 0.7896 0.7896
Echinococcus granulosus tubulin delta chain 0.0134 0.1591 0.1566
Brugia malayi beta-tubulin, identical 0.062 0.7896 0.7896
Echinococcus granulosus thioredoxin glutathione reductase 0.0044 0.0428 0.04
Echinococcus multilocularis Tubulin beta 2C chain 0.062 0.7896 0.789
Trypanosoma brucei alpha tubulin 0.0403 0.5079 0.6408
Loa Loa (eye worm) tubulin beta-1 chain 0.062 0.7896 0.789
Trypanosoma brucei epsilon tubulin 0.0308 0.3854 0.4847
Trichomonas vaginalis tubulin alpha chain, putative 0.0175 0.2117 0.2632
Giardia lamblia Beta tubulin 0.062 0.7896 1
Echinococcus multilocularis tubulin alpha chain 0.0403 0.5079 0.5065
Trypanosoma brucei beta tubulin 0.062 0.7896 1
Brugia malayi tubulin alpha-2 chain 0.0403 0.5079 0.5079
Echinococcus multilocularis Tubulin beta 2C chain 0.062 0.7896 0.789
Echinococcus granulosus cpg binding protein 0.0032 0.0269 0.024
Trichomonas vaginalis tubulin, putative 0.062 0.7896 1
Schistosoma mansoni tubulin subunit beta 0.0134 0.1591 0.1566
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0043 0.0417 0.0464
Trichomonas vaginalis tubulin epsilon chain, putative 0.062 0.7896 1
Loa Loa (eye worm) tubulin gamma chain 0.0308 0.3854 0.3837
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.0428 0.0479
Giardia lamblia Gamma tubulin 0.0308 0.3854 0.4847
Brugia malayi Protein kinase domain containing protein 0.0248 0.3072 0.3072
Echinococcus granulosus epidermal growth factor receptor 0.0782 1 1
Giardia lamblia Epsilon tubulin 0.0134 0.1591 0.1961
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.016 0.0137
Schistosoma mansoni tyrosine kinase 0.0467 0.5904 0.5892
Echinococcus granulosus geminin 0.0179 0.2169 0.2146
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0043 0.0417 0.0417
Trypanosoma brucei alpha tubulin 0.0403 0.5079 0.6408
Echinococcus multilocularis tubulin, beta 4A class IVa 0.062 0.7896 0.789
Echinococcus multilocularis tubulin beta 1 chain 0.062 0.7896 0.789
Schistosoma mansoni hypothetical protein 0.0179 0.2169 0.2146
Trypanosoma brucei epsilon tubulin 0.0308 0.3854 0.4847
Plasmodium vivax tubulin gamma chain, putative 0.0308 0.3854 0.4847
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0248 0.3072 0.3051
Trypanosoma brucei alpha tubulin, putative 0.0175 0.2117 0.2632
Leishmania major trypanothione reductase 0.0044 0.0428 0.0479
Schistosoma mansoni tubulin subunit delta 0.0134 0.1591 0.1566
Echinococcus granulosus Tubulin beta 2C chain 0.062 0.7896 0.789
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0015 0.0053 0.0053
Schistosoma mansoni tubulin subunit alpha 0.0403 0.5079 0.5065
Schistosoma mansoni cpg binding protein 0.0032 0.0269 0.024
Echinococcus granulosus tubulin alpha 3 chain 0.0403 0.5079 0.5065
Leishmania major beta tubulin 0.062 0.7896 1
Echinococcus granulosus insulin receptor 0.0248 0.3072 0.3051
Loa Loa (eye worm) TK/INSR protein kinase 0.0248 0.3072 0.3051
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0269 0.3342 0.4193
Echinococcus multilocularis peroxisome assembly protein 26 0.0403 0.5079 0.5065
Leishmania major beta tubulin 0.062 0.7896 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0228 0.2815 0.2794
Echinococcus multilocularis geminin 0.0179 0.2169 0.2146
Echinococcus granulosus tubulin alpha 1C chain 0.0403 0.5079 0.5065
Echinococcus multilocularis tubulin gamma 1 chain 0.0308 0.3854 0.3837
Leishmania major beta tubulin 0.062 0.7896 1
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0134 0.1591 0.1961
Trichomonas vaginalis tubulin gamma chain, putative 0.0134 0.1591 0.1961
Loa Loa (eye worm) hypothetical protein 0.0269 0.3342 0.3323
Brugia malayi Tubulin alpha chain 0.0403 0.5079 0.5079
Schistosoma mansoni tubulin subunit beta 0.062 0.7896 0.789
Trypanosoma brucei tubulin delta chain 0.0134 0.1591 0.1961
Echinococcus multilocularis tubulin alpha chain 0.0403 0.5079 0.5065
Brugia malayi Tubulin beta chain 0.0134 0.1591 0.1591
Loa Loa (eye worm) tubulin beta chain 0.0134 0.1591 0.1566
Echinococcus granulosus tubulin alpha 0.0308 0.3854 0.3837
Schistosoma mansoni glutaminase 0.0256 0.3175 0.3155
Loa Loa (eye worm) TK/EGFR protein kinase 0.0782 1 1
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.016 0.0137
Echinococcus multilocularis thioredoxin glutathione reductase 0.0044 0.0428 0.04
Plasmodium vivax delta tubulin, putative 0.0134 0.1591 0.1961
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.131 0.8177
Trichomonas vaginalis tubulin alpha chain, putative 0.0308 0.3854 0.4847
Trichomonas vaginalis tubulin epsilon chain, putative 0.0403 0.5079 0.6408
Echinococcus multilocularis tubulin alpha 3 chain 0.0403 0.5079 0.5065
Leishmania major zeta tubulin, putative 0.0134 0.1591 0.1961
Onchocerca volvulus 0.0175 0.2117 1
Brugia malayi hypothetical protein 0.0015 0.0051 0.0051
Leishmania major beta tubulin 0.062 0.7896 1
Entamoeba histolytica tubulin alpha-1 chain 0.0403 0.5079 0.3029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0417 0.0389
Leishmania major delta tubulin, putative 0.0134 0.1591 0.1961
Plasmodium falciparum tubulin epsilon chain, putative 0.0308 0.3854 0.4847
Leishmania major gamma-tubulin 0.0308 0.3854 0.4847
Echinococcus granulosus tubulin subunit TubB 0.0403 0.5079 0.5065
Trypanosoma brucei epsilon tubulin 0.0308 0.3854 0.4847
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Trichomonas vaginalis conserved hypothetical protein 0.0134 0.1591 0.1961
Echinococcus multilocularis tubulin alpha chain 0.0403 0.5079 0.5065
Mycobacterium ulcerans cell division protein FtsZ 0.0134 0.1591 0.4926
Leishmania major beta tubulin 0.062 0.7896 1
Plasmodium falciparum thioredoxin reductase 0.0044 0.0428 0.0479
Toxoplasma gondii beta-tubulin, putative 0.062 0.7896 1
Trichomonas vaginalis tubulin gamma chain, putative 0.062 0.7896 1
Schistosoma mansoni tubulin subunit alpha 0.0403 0.5079 0.5065
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0101 0.1164 0.7226
Brugia malayi glutaminase DH11.1 0.0256 0.3175 0.3175
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.016 0.0137
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Loa Loa (eye worm) glutaminase 2 0.0256 0.3175 0.3155
Loa Loa (eye worm) beta-tubulin 0.062 0.7896 0.789
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Giardia lamblia Beta tubulin 0.062 0.7896 1
Leishmania major beta tubulin 0.062 0.7896 1
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.016 0.0137
Schistosoma mansoni alpha tubulin 0.0403 0.5079 0.5065
Schistosoma mansoni tyrosine kinase 0.0471 0.5966 0.5954
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0101 0.1164 0.7226
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0269 0.3342 0.3323
Toxoplasma gondii alpha tubulin TUBA1 0.0403 0.5079 0.6408
Trypanosoma cruzi tubulin gamma chain 0.0308 0.3854 0.4847
Loa Loa (eye worm) tubulin beta-2A chain 0.062 0.7896 0.789
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Mycobacterium tuberculosis Cell division protein FtsZ 0.0134 0.1591 1
Plasmodium falciparum glutathione reductase 0.0044 0.0428 0.0479
Echinococcus granulosus alpha tubulin 0.0403 0.5079 0.5065
Trichomonas vaginalis tubulin epsilon chain, putative 0.062 0.7896 1
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0043 0.0417 0.0389
Loa Loa (eye worm) tubulin beta-4 chain 0.062 0.7896 0.789
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0471 0.5966 0.5954
Loa Loa (eye worm) hypothetical protein 0.0228 0.2815 0.2794
Leishmania major beta tubulin 0.062 0.7896 1
Schistosoma mansoni cpg binding protein 0.003 0.0246 0.0218
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0101 0.1164 0.7226
Brugia malayi hypothetical protein 0.0024 0.016 0.016
Leishmania major beta tubulin 0.062 0.7896 1
Leishmania major beta tubulin 0.062 0.7896 1
Brugia malayi glutathione reductase 0.0044 0.0428 0.0428
Trypanosoma cruzi alpha tubulin, putative 0.0403 0.5079 0.6408
Trichomonas vaginalis glutaminase, putative 0.0256 0.3175 0.398
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0015 0.0053 0.0024
Leishmania major hypothetical protein, conserved 0.0023 0.0147 0.012
Echinococcus granulosus tubulin beta 1 chain 0.062 0.7896 0.789
Brugia malayi Tubulin alpha-2 chain 0.0403 0.5079 0.5079
Echinococcus granulosus Tubulin beta 2C chain 0.062 0.7896 0.789
Mycobacterium tuberculosis Probable reductase 0.0101 0.1164 0.7226
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0308 0.3854 0.4847
Trypanosoma brucei trypanothione reductase 0.0044 0.0428 0.0479
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0367 0.4617 0.4601
Plasmodium vivax tubulin epsilon chain, putative 0.0308 0.3854 0.4847
Toxoplasma gondii thioredoxin reductase 0.0044 0.0428 0.0479
Trypanosoma brucei tubulin gamma chain 0.0308 0.3854 0.4847
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0015 0.0053 0.5
Leishmania major beta tubulin 0.062 0.7896 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.009 0.009
Schistosoma mansoni tyrosine kinase 0.0782 1 1
Entamoeba histolytica tubulin alpha chain, putative 0.0403 0.5079 0.3029
Plasmodium vivax tubulin beta chain, putative 0.062 0.7896 1
Leishmania major beta tubulin 0.062 0.7896 1
Brugia malayi alpha-tubulin 0.0403 0.5079 0.5079
Trypanosoma brucei alpha tubulin 0.0403 0.5079 0.6408
Loa Loa (eye worm) tubulin alpha chain 0.0403 0.5079 0.5065
Echinococcus granulosus tubulin alpha 1C chain 0.0403 0.5079 0.5065
Echinococcus multilocularis insulin receptor 0.0248 0.3072 0.3051
Brugia malayi Cell division protein ftsZ 0.0134 0.1591 0.1591
Schistosoma mansoni tyrosine kinase 0.0467 0.5904 0.5892
Schistosoma mansoni tyrosine kinase 0.0471 0.5966 0.5954
Brugia malayi Tubulin alpha chain 0.0134 0.1591 0.1591
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0112 0.131 0.8177
Trichomonas vaginalis tubulin, putative 0.0134 0.1591 0.1961
Echinococcus multilocularis tubulin subunit beta 0.062 0.7896 0.789
Trypanosoma cruzi epsilon tubulin, putative 0.0308 0.3854 0.4847
Echinococcus granulosus tubulin alpha chain 0.0403 0.5079 0.5065
Echinococcus multilocularis epidermal growth factor receptor 0.0782 1 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0308 0.3854 0.4847
Brugia malayi Tubulin beta chain 0.0175 0.2117 0.2117
Trypanosoma cruzi tubulin delta chain 0.0134 0.1591 0.1961
Trichomonas vaginalis tubulin beta chain, putative 0.0403 0.5079 0.6408
Loa Loa (eye worm) tubulin alpha 2 0.0269 0.3342 0.3323
Echinococcus multilocularis 0.0317 0.3968 0.395
Echinococcus granulosus tubulin epsilon chain 0.0308 0.3854 0.3837
Echinococcus granulosus tubulin subunit beta 0.062 0.7896 0.789
Trichomonas vaginalis tubulin alpha chain, putative 0.0175 0.2117 0.2632
Loa Loa (eye worm) tubulin alpha 2 0.0269 0.3342 0.3323
Schistosoma mansoni tubulin subunit beta 0.062 0.7896 0.789
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0112 0.131 0.8177
Plasmodium falciparum tubulin gamma chain 0.0308 0.3854 0.4847
Giardia lamblia Alpha-tubulin 0.0403 0.5079 0.6408
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0686 0.0659
Echinococcus granulosus dnaJ subfamily B 0.0431 0.5442 0.5429
Schistosoma mansoni tubulin subunit beta 0.062 0.7896 0.789
Schistosoma mansoni tubulin subunit beta 0.062 0.7896 0.789
Leishmania major beta tubulin 0.062 0.7896 1
Trypanosoma cruzi tubulin delta chain 0.0134 0.1591 0.1961
Plasmodium vivax glutathione reductase, putative 0.0044 0.0428 0.0479
Loa Loa (eye worm) glutaminase 0.0256 0.3175 0.3155
Echinococcus granulosus Tubulin beta 2C chain 0.062 0.7896 0.789
Trypanosoma cruzi epsilon tubulin, putative 0.0308 0.3854 0.4847
Entamoeba histolytica tubulin family protein 0.062 0.7896 1
Giardia lamblia Beta tubulin 0.062 0.7896 1
Plasmodium falciparum tubulin delta chain, putative 0.0134 0.1591 0.1961
Schistosoma mansoni tubulin subunit alpha 0.0134 0.1591 0.1566
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0134 0.1591 0.1961
Schistosoma mansoni tubulin subunit gamma 0.0308 0.3854 0.3837
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0101 0.1164 0.7226
Onchocerca volvulus 0.003 0.0246 0.0183
Schistosoma mansoni tubulin subunit alpha 0.0403 0.5079 0.5065
Echinococcus multilocularis adhesion regulating molecule 1 0.0043 0.0417 0.0389
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0228 0.2815 0.3522
Schistosoma mansoni tyrosine kinase 0.0248 0.3072 0.3051
Echinococcus granulosus tubulin alpha chain 0.0403 0.5079 0.5065
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0597 0.0694
Toxoplasma gondii beta-1 tubulin, putative 0.062 0.7896 1
Entamoeba histolytica tubulin family protein 0.062 0.7896 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0403 0.5079 0.5065
Echinococcus granulosus Tubulin alpha 1 chain 0.0403 0.5079 0.5065
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Schistosoma mansoni alpha tubulin 0.0403 0.5079 0.5065
Loa Loa (eye worm) glutathione reductase 0.0044 0.0428 0.04
Trichomonas vaginalis tubulin epsilon chain, putative 0.0134 0.1591 0.1961
Echinococcus multilocularis tubulin alpha 1C chain 0.0403 0.5079 0.5065
Echinococcus granulosus beta tubulin 0.062 0.7896 0.789
Giardia lamblia Delta tubulin 0.0134 0.1591 0.1961
Trypanosoma brucei beta tubulin 0.062 0.7896 1
Leishmania major beta tubulin 0.062 0.7896 1
Trichomonas vaginalis tubulin beta chain, putative 0.0175 0.2117 0.2632
Echinococcus multilocularis tubulin subunit TubB 0.0403 0.5079 0.5065
Leishmania major alpha tubulin 0.0403 0.5079 0.6408
Brugia malayi Tubulin gamma chain 0.0308 0.3854 0.3854
Trichomonas vaginalis tubulin beta chain, putative 0.062 0.7896 1
Echinococcus multilocularis tubulin alpha chain 0.0403 0.5079 0.5065
Echinococcus multilocularis Tubulin alpha 1 chain 0.0403 0.5079 0.5065
Leishmania major beta tubulin 0.062 0.7896 1
Leishmania major epsilon tubulin, putative 0.0308 0.3854 0.4847
Echinococcus multilocularis tubulin delta chain 0.0134 0.1591 0.1566

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.