Detailed information for compound 1851497

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 805.877 | Formula: C40H62Cl2N8O5
  • H donors: 2 H acceptors: 7 LogP: 5.51 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCC1CN(CCN1C(=O)CCn1cnc2c1ncnc2N1CCC(C1)N)CC(=O)O[C@@H]1C[C@@](C)(C=C)[C@@H](O)[C@@H]([C@]23[C@@H]([C@@]1(C)[C@H](C)CC2)C(=O)CC3)C.Cl.Cl
  • InChi: 1S/C40H60N8O5.2ClH/c1-7-28-21-45(17-18-48(28)31(50)12-16-47-24-44-33-36(42-23-43-37(33)47)46-15-11-27(41)20-46)22-32(51)53-30-19-38(5,8-2)35(52)26(4)40-13-9-25(3)39(30,6)34(40)29(49)10-14-40;;/h8,23-28,30,34-35,52H,2,7,9-22,41H2,1,3-6H3;2*1H/t25-,26+,27?,28?,30-,34-,35+,38-,39+,40+;;/m1../s1
  • InChiKey: NTNSJOSYYFNGQW-MGSWFRRLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis TK family protein kinase 0.053 0.9987 1
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase HCK 0.053 0.9987 0.9987
Brugia malayi protein-tyrosine kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0167 0.0156
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0009 0.0042 0.0031
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0459 0.0419
Leishmania major protein kinase, putative 0.0531 1 1
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.002 0.0252 0.0241
Loa Loa (eye worm) TK/EGFR protein kinase 0.053 0.9987 1
Brugia malayi Cation transporter family protein 0.002 0.0252 0.0211
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0073 0.0031
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Schistosoma mansoni DNA helicase recq5 0.0031 0.0459 0.0449
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Leishmania major hypothetical protein, conserved 0.053 0.9987 0.9987
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.035 0.5
Echinococcus multilocularis heat shock protein 70 0.053 0.9988 0.9988
Loa Loa (eye worm) RGC/RGC protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0252 0.0241
Echinococcus granulosus tyrosine kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0372 0.0361
Echinococcus granulosus tyrosine protein kinase Btk29A 0.053 0.9987 0.9987
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0208 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Echinococcus multilocularis tyrosine protein kinase csk 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.053 0.9987 0.9987
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0073 0.0031
Echinococcus multilocularis raf serine:threonine protein kinase 0.053 0.9987 0.9987
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0514 0.0355
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Schistosoma mansoni coup transcription factor 0.0011 0.0073 0.0062
Brugia malayi C-terminal src kinase protein 1 0.053 0.9987 1
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.002 0.0252 0.0211
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.053 0.9987 0.9987
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.002 0.0252 0.0241
Echinococcus granulosus glycine receptor subunit beta 0.002 0.0252 0.0241
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0252 0.0241
Loa Loa (eye worm) hypothetical protein 0.003 0.0428 0.0388
Schistosoma mansoni apoferritin-2 0.0009 0.0039 0.0028
Echinococcus granulosus expressed protein 0.0009 0.0039 0.0028
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Echinococcus multilocularis expressed protein 0.0009 0.0039 0.0028
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Plasmodium falciparum protein kinase, putative 0.053 0.9987 0.9987
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.284 1
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Onchocerca volvulus 0.002 0.0252 0.0211
Entamoeba histolytica ankyrin repeat protein 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0531 1 1
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0252 0.0241
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.002 0.0252 0.0241
Onchocerca volvulus 0.002 0.0252 0.0211
Entamoeba histolytica SH2-protein kinase domain containing protein 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0073 0.0062
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0009 0.0042 0.0031
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Brugia malayi hypothetical protein 0.0022 0.0274 0.0233
Schistosoma mansoni lozenge 0.0061 0.1021 0.1011
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Brugia malayi Furin-like cysteine rich region family protein 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.035 0.0525
Onchocerca volvulus 0.053 0.9987 1
Loa Loa (eye worm) TK/ALK protein kinase 0.053 0.9987 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0016 0.0164 0.0153
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0073 0.0031
Schistosoma mansoni nAChR subunit 0.002 0.0252 0.0241
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0721 0.071
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0255 0.0092
Schistosoma mansoni carbonyl reductase 0.0027 0.0372 0.0361
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Schistosoma mansoni terminal deoxycytidyl transferase 0.0016 0.0164 0.0153
Giardia lamblia Kinase, NEK 0.053 0.9987 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0255 0.0185
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0073 0.0031
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.002 0.0252 0.0241
Schistosoma mansoni protein kinase 0.0531 1 1
Echinococcus multilocularis activated cdc42 kinase 1 0.053 0.9987 0.9987
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Brugia malayi ecdysteroid receptor 0.0011 0.0073 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.053 0.9987 0.9987
Plasmodium vivax tyrosine kinase-like protein, putative 0.053 0.9987 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0362 0.0271
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Onchocerca volvulus 0.053 0.9987 1
Echinococcus granulosus raf serine:threonine protein kinase 0.053 0.9987 0.9987
Leishmania major DNA polymerase kappa, putative 0.0023 0.0302 0.014
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0164 0.0123
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus RUN 0.0022 0.0274 0.0263
Trypanosoma brucei DNA polymerase eta, putative 0.0016 0.0164 0.0094
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.1239 0.1229
Echinococcus multilocularis activin receptor type 0.0531 1 1
Echinococcus multilocularis dnaJ subfamily B 0.0447 0.8393 0.8392
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0372 0.0361
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Echinococcus multilocularis epidermal growth factor receptor 0.053 0.9987 0.9987
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.035 0.111
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Echinococcus multilocularis dna polymerase eta 0.0016 0.0164 0.0153
Loa Loa (eye worm) TK/DDR protein kinase 0.053 0.9987 1
Onchocerca volvulus 0.0031 0.0461 0.0421
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.053 0.9987 0.9987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0073 0.0031
Schistosoma mansoni cpg binding protein 0.0033 0.0496 0.0485
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.002 0.0252 0.0241
Schistosoma mansoni tyrosine-protein kinase fps85d 0.053 0.9987 0.9987
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0073 0.0031
Giardia lamblia Kinase, NEK 0.053 0.9987 1
Schistosoma mansoni nAChR subunit 0.002 0.0252 0.0241
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.053 0.9987 1
Entamoeba histolytica serine/threonine kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.002 0.0252 0.0241
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Echinococcus multilocularis kinase suppressor of Ras 1 0.053 0.9987 0.9987
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0129 0.2322 0.2314
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Trichomonas vaginalis serine-threonine protein kinase, putative 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Trypanosoma cruzi protein kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase ABL1 0.053 0.9987 0.9987
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0073 0.0031
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0274 0.0263
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.053 0.9987 0.9987
Echinococcus granulosus tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.053 0.9987 0.9987
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0073 0.0062
Schistosoma mansoni tyrosine protein kinase 0.053 0.9987 0.9987
Onchocerca volvulus 0.0011 0.0073 0.003
Leishmania major short chain dehydrogenase, putative 0.0027 0.0372 0.0211
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0073 0.0062
Echinococcus multilocularis tyrosine protein kinase Fgr 0.053 0.9987 0.9987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0073 0.0031
Entamoeba histolytica deoxycytidyl transferase, putative 0.0016 0.0164 0.0092
Echinococcus granulosus natriuretic peptide receptor 1 0.053 0.9987 0.9987
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.002 0.0252 0.0211
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.002 0.0252 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0073 0.0031
Schistosoma mansoni apoferritin-2 0.0009 0.0039 0.0028
Schistosoma mansoni ephrin receptor 0.053 0.9987 0.9987
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0073 0.0062
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0274 0.0233
Onchocerca volvulus 0.0022 0.0274 0.0233
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0659 0.0649
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0255 0.0183
Loa Loa (eye worm) ACC-1 protein 0.002 0.0252 0.0211
Loa Loa (eye worm) TK/ABL protein kinase 0.053 0.9987 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0459 0.0419
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Echinococcus multilocularis protein KINase family member (kin 25) 0.053 0.9987 0.9987
Loa Loa (eye worm) RGC/RGC protein kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase csk 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Trichomonas vaginalis DNA helicase recq, putative 0.0034 0.0514 0.0477
Echinococcus granulosus fibroblast growth factor receptor 4 0.053 0.9987 0.9987
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0073 0.003
Schistosoma mansoni serine/threonine RGC 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0274 0.0263
Entamoeba histolytica serine/threonine kinase, putative 0.053 0.9987 0.9987
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0252 0.0211
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0073 0.0062
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0255 0.6929
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0073 0.0062
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Brugia malayi Cation transporter family protein 0.002 0.0252 0.0211
Brugia malayi Probable tyrosine-protein kinase kin-31 0.053 0.9987 1
Schistosoma mansoni nAChR subunit 0.002 0.0252 0.0241
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0459 0.0449
Brugia malayi Probable tyrosine-protein kinase kin-31 0.053 0.9987 1
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.002 0.0252 0.0211
Echinococcus multilocularis tyrosine protein kinase shark 0.053 0.9987 0.9987
Echinococcus granulosus dna polymerase kappa 0.0045 0.0719 0.0708
Entamoeba histolytica receptor protein kinase, putative 0.053 0.9987 0.9987
Brugia malayi Guanylyl cyclase protein 23 0.053 0.9987 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0011 0.0073 0.003
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Echinococcus granulosus cpg binding protein 0.0033 0.0496 0.0485
Plasmodium falciparum protein kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni acetylcholine receptor-related 0.0009 0.0042 0.0031
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0719 0.0564
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0255 0.0364
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis FL cytokine receptor 0.053 0.9987 0.9987
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0073 0.0062
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0129 0.2322 0.2314
Schistosoma mansoni DNA polymerase eta 0.0016 0.0164 0.0153
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0016 0.0164 0.0153
Loa Loa (eye worm) hypothetical protein 0.0484 0.9101 0.9108
Trypanosoma brucei protein kinase, putative 0.0531 1 1
Echinococcus granulosus tyrosine protein kinase shark 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/ACK protein kinase 0.053 0.9987 1
Plasmodium falciparum tyrosine kinase-like protein 0.053 0.9987 0.9987
Onchocerca volvulus 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase Blk 0.053 0.9987 0.9987
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0255 0.0244
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0372 0.0361
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0073 0.003
Entamoeba histolytica serine/threonine kinase, putative 0.053 0.9987 0.9987
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0073 0.0031
Echinococcus multilocularis transfer RNA-Thr 0.053 0.9987 0.9987
Loa Loa (eye worm) serine/threonine protein kinase 0.053 0.9987 1
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.002 0.0252 0.0211
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0255 0.0897
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0459 0.0449
Schistosoma mansoni lipoxygenase 0.0129 0.2322 0.2314
Echinococcus granulosus dnaJ subfamily B 0.0447 0.8393 0.8392
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0372 0.0361
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.1239 0.1204
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.1596 0.1587
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0048 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.1239 0.1229
Trichomonas vaginalis AGC family protein kinase 0.053 0.9987 1
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0073 0.0031
Trypanosoma cruzi protein kinase, putative 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Echinococcus granulosus tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.053 0.9987 0.9987
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.053 0.9987 1
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.0252 0.0241
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0252 0.0211
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0459 0.0419
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0531 1 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.053 0.9987 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0459 0.0419
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.053 0.9987 1
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.035 0.0282
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.053 0.9987 0.9987
Onchocerca volvulus 0.0022 0.0274 0.0233
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.035 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.053 0.9987 0.9987
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.053 0.9987 0.9987
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0274 0.0263
Brugia malayi hypothetical protein 0.053 0.9987 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0167 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0252 0.0211
Trichomonas vaginalis protein tyrosine kinase, putative 0.053 0.9987 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.002 0.0252 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0073 0.0031
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0073 0.0062
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.002 0.0252 0.0241
Entamoeba histolytica recQ family DNA helicase 0.0016 0.0167 0.0095
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0252 0.0211
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.053 0.9987 0.9987
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0073 0.0062
Echinococcus multilocularis tyrosine protein kinase Src64B 0.053 0.9987 0.9987
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni nAChR subunit 0.0009 0.0042 0.0031
Echinococcus multilocularis ephrin type A receptor 4 A 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.0531 1 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.053 0.9987 1
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.053 0.9987 1
Giardia lamblia Kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Onchocerca volvulus Tyrosine kinase homolog 0.053 0.9987 1
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Echinococcus multilocularis tyrosine kinase 0.053 0.9987 0.9987
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0016 0.0164 0.0123
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0252 0.0211
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.002 0.0252 0.0241
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0073 0.0062
Toxoplasma gondii carbonyl reductase 1, putative 0.0027 0.0372 0.0281
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0073 0.0062
Loa Loa (eye worm) ACC-1 protein 0.002 0.0252 0.0211
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.0719 0.0653
Giardia lamblia Protein 21.1 0.053 0.9987 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0045 0.0719 0.0683
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0164 0.0123
Schistosoma mansoni cpg binding protein 0.0033 0.0496 0.0485
Trypanosoma brucei unspecified product 0.0038 0.0581 0.0514
Schistosoma mansoni src-type protein tyrosine kinase-related 0.053 0.9987 0.9987
Schistosoma mansoni nAChR subunit 0.002 0.0252 0.0241
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0252 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.053 0.9987 0.9987
Echinococcus multilocularis nAChR subunit 0.002 0.0252 0.0241
Echinococcus granulosus epidermal growth factor receptor 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.053 0.9987 0.9987
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.1239 0.1093
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Brugia malayi hypothetical protein 0.053 0.9987 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0073 0.0062
Brugia malayi SH2 domain containing protein 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Trichomonas vaginalis DNA polymerase eta, putative 0.0045 0.0719 0.0683
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.053 0.9987 0.9987
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Schistosoma mansoni ephrin receptor 0.053 0.9987 0.9987
Schistosoma mansoni hypothetical protein 0.0447 0.8393 0.8392
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0073 0.0062
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis protein kinase 0.053 0.9987 0.9987
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Entamoeba histolytica tyrosin kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0073 0.0062
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Echinococcus granulosus ferritin 0.0009 0.0039 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.053 0.9987 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0073 0.0062
Brugia malayi hypothetical protein 0.053 0.9987 1
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0372 0.0361
Echinococcus multilocularis tyrosine protein kinase Abl 0.053 0.9987 0.9987
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis protein tyrosine kinase 0.053 0.9987 0.9987
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.1239 0.1175
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.002 0.0252 0.0241
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0009 0.0042 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/FAK protein kinase 0.053 0.9987 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.053 0.9987 0.9987
Echinococcus multilocularis retinal guanylyl cyclase 2 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0073 0.0062
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0302 0.1063
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0274 0.0121
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0255 0.0217
Brugia malayi steroid hormone receptor 0.0011 0.0073 0.0031
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0039 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Entamoeba histolytica serine/threonine kinase, putative 0.053 0.9987 0.9987
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Echinococcus multilocularis ferritin 0.0009 0.0039 0.0028
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.053 0.9987 0.9987
Onchocerca volvulus 0.002 0.0252 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.053 0.9987 1
Brugia malayi ephrin receptor 1 precursor 0.053 0.9987 1
Trypanosoma brucei DNA polymerase IV, putative 0.0045 0.0719 0.0653
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.053 0.9987 1
Trypanosoma brucei Pseudokinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni acetylcholine receptor subunit beta 0.0009 0.0042 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Schistosoma mansoni rab6-interacting 0.0022 0.0274 0.0263
Loa Loa (eye worm) histone methyltransferase 0.001 0.0048 0.0005
Echinococcus granulosus tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0302 0.0233
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.1133 0.1123
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.053 0.9987 0.9987
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0073 0.0062
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0252 0.0211
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0073 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0073 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis tyrosine protein kinase csk 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.053 0.9987 0.9987
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0255 0.0101
Schistosoma mansoni neurotransmitter gated ion channel 0.0011 0.0073 0.0061
Echinococcus granulosus ephrin type A receptor 4 A 0.053 0.9987 0.9987
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Brugia malayi Tyrosine-protein kinase PR2 0.053 0.9987 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.9987 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.053 0.9987 0.9987
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.0719 0.2426
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0514 0.0446
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Toxoplasma gondii protein kinase domain-containing protein 0.053 0.9987 0.9987
Schistosoma mansoni nAChR subunit 0.002 0.0252 0.0241
Echinococcus multilocularis carbonyl reductase 1 0.0022 0.0291 0.0281
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0255 0.0769
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Echinococcus granulosus insulin receptor 0.053 0.9987 0.9987
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0719 0.0564
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.053 0.9987 1
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0073 0.0062
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0459 0.0449
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0073 0.0062
Loa Loa (eye worm) hypothetical protein 0.0091 0.1596 0.1563
Echinococcus granulosus tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0073 0.0062
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0045 0.0003
Onchocerca volvulus 0.0011 0.0073 0.0031
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0459 0.021
Schistosoma mansoni ferritin 0.0009 0.0039 0.0028
Onchocerca volvulus 0.0011 0.0073 0.003
Echinococcus granulosus carbonyl reductase 1 0.0022 0.0291 0.0281
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.0252 0.0241
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.1596 0.1587
Schistosoma mansoni polycystin 1-related 0.0022 0.0274 0.0263
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.002 0.0252 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0073 0.0031
Onchocerca volvulus 0.053 0.9987 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.0416 0.0406
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.0252 0.0241
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Echinococcus multilocularis retinal guanylyl cyclase 2 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Schistosoma mansoni serine/threonine protein kinase 0.053 0.9987 0.9987
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.053 0.9987 0.9987
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.035 0.111
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.002 0.0252 0.0241
Onchocerca volvulus 0.053 0.9987 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Echinococcus multilocularis natriuretic peptide receptor 1 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Schistosoma mansoni ap endonuclease 0.0021 0.0255 0.0244
Trypanosoma cruzi short chain dehydrogenase, putative 0.0027 0.0372 0.0211
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Brugia malayi SRC-1 0.053 0.9987 1
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0009 0.0042 0.0031
Entamoeba histolytica tyrosin kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica tyrosin kinase, putative 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0016 0.0167 0.0125
Onchocerca volvulus 0.0484 0.9101 0.9108
Schistosoma mansoni ferritin 0.0009 0.0039 0.0028
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Brugia malayi excitatory GABA receptor EXP-1A 0.002 0.0252 0.0211
Loa Loa (eye worm) TK/INSR protein kinase 0.053 0.9987 1
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.053 0.9987 0.9987
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0073 0.0062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0048 0.0037
Schistosoma mansoni protein tyrosine kinase 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase Srms 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase Blk 0.053 0.9987 0.9987
Schistosoma mansoni loxhd1 0.0022 0.0274 0.0263
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Echinococcus granulosus nAChR subunit 0.002 0.0252 0.0241
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0255 0.0092
Schistosoma mansoni carbonyl reductase 0.0022 0.0291 0.0281
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.053 0.9987 0.9987
Echinococcus granulosus tyrosine protein kinase pr2 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/ROR protein kinase 0.053 0.9987 1
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Toxoplasma gondii protein kinase 0.053 0.9987 0.9987
Schistosoma mansoni protein kinase 0.0531 1 1
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase 0.053 0.9987 0.9987
Echinococcus granulosus tyrosine protein kinase ABL1 0.053 0.9987 0.9987
Echinococcus multilocularis protein kinase 0.053 0.9987 0.9987
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.1239 0.1229
Toxoplasma gondii exonuclease III APE 0.0021 0.0255 0.0162
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0514 0.0355
Loa Loa (eye worm) hypothetical protein 0.0016 0.0164 0.0123
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Echinococcus granulosus activated cdc42 kinase 1 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0011 0.0073 0.003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0252 0.0241
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.053 0.9987 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.053 0.9987 0.9987
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0255 0.0217
Echinococcus granulosus receptor type guanylyl cyclase 0.053 0.9987 0.9987
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Schistosoma mansoni hypothetical protein 0.053 0.9987 0.9987
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0073 0.0031
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.5958 0.5929
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Treponema pallidum ATP-dependent DNA helicase 0.0016 0.0167 0.0215
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.035 0.0189
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0252 0.0241
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.1239 0.1093
Trichomonas vaginalis conserved hypothetical protein 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0073 0.0062
Echinococcus multilocularis cpg binding protein 0.0033 0.0496 0.0485
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.053 0.9987 1
Toxoplasma gondii STE kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.0374 0.0223
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Entamoeba histolytica recQ family helicase, putative 0.0034 0.0514 0.0444
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine kinase 0.053 0.9987 0.9987
Brugia malayi polk-prov protein 0.0034 0.0511 0.0471
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.002 0.0252 0.0211
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0252 0.0241
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0531 1 1
Schistosoma mansoni ap endonuclease 0.0021 0.0255 0.0244
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0208 0.0139
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.002 0.0252 0.0211
Onchocerca volvulus 0.002 0.0252 0.0211
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica receptor protein kinase, putative 0.053 0.9987 0.9987
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.1239 0.1204
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Schistosoma mansoni ferritin light chain 0.0009 0.0039 0.0028
Echinococcus granulosus carbonyl reductase 1 0.0027 0.0372 0.0361
Brugia malayi Cation transporter family protein 0.002 0.0252 0.0211
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Brugia malayi SH2 domain containing protein 0.053 0.9987 1
Echinococcus granulosus epidermal growth factor receptor 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0252 0.0211
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0252 0.0211
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Onchocerca volvulus 0.0027 0.0372 0.0331
Plasmodium falciparum tyrosine kinase-like protein 0.053 0.9987 0.9987
Brugia malayi Doublecortin family protein 0.0022 0.0274 0.0233
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.053 0.9987 0.9987
Mycobacterium leprae conserved hypothetical protein 0.0026 0.035 0.111
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0073 0.0061
Brugia malayi Receptor family ligand binding region containing protein 0.053 0.9987 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.053 0.9987 0.9987
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0255 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.053 0.9987 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0252 0.0211
Schistosoma mansoni ferritin 0.0009 0.0039 0.0028
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0721 0.0685
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis dna polymerase kappa 0.0045 0.0719 0.0708
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.053 0.9987 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.053 0.9987 0.9987
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0073 0.0031
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.035 0.0259
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0252 0.0241
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0721 0.0685
Onchocerca volvulus 0.053 0.9987 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.1239 0.1093
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Echinococcus multilocularis epidermal growth factor receptor 0.053 0.9987 0.9987
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0073 0.0031
Loa Loa (eye worm) runx1 0.0061 0.1021 0.0984
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Schistosoma mansoni cpg binding protein 0.0031 0.0461 0.0451
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0252 0.0241
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.1596 0.1563
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.002 0.0252 0.0211
Onchocerca volvulus 0.053 0.9987 1
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Brugia malayi Tyrosine-protein kinase abl-1 0.053 0.9987 1
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0073 0.0031
Plasmodium vivax protein kinase, putative 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) TK/Met protein kinase 0.053 0.9987 1
Schistosoma mansoni carbonyl reductase 0.0027 0.0372 0.0361
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0719 0.0564
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.284 1
Mycobacterium ulcerans DNA polymerase IV 0.0045 0.0719 0.2426
Echinococcus multilocularis nAChR subunit 0.0011 0.0073 0.0061
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Entamoeba histolytica ankyrin repeat protein 0.053 0.9987 0.9987
Schistosoma mansoni nAChR subunit 0.002 0.0252 0.0241
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0459 0.0369
Echinococcus granulosus bloom syndrome protein 0.0045 0.0721 0.071
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Trichomonas vaginalis STE family protein kinase 0.053 0.9987 1
Onchocerca volvulus 0.053 0.9987 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0997 0.0912
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Brugia malayi hypothetical protein 0.0484 0.9101 0.9108
Echinococcus granulosus protein kinase 0.053 0.9987 0.9987
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0022 0.0274 0.0233
Echinococcus multilocularis c src tyrosine kinase 0.053 0.9987 0.9987
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.002 0.0252 0.0241
Loa Loa (eye worm) hypothetical protein 0.0022 0.0274 0.0233
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0167 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.5958 0.5929
Loa Loa (eye worm) TK protein kinase 0.053 0.9987 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0073 0.0062
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.035 0.0098
Schistosoma mansoni hypothetical protein 0.0022 0.0274 0.0263
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0073 0.0062
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0659 0.0649
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.002 0.0252 0.0211
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0461 0.0421
Trichomonas vaginalis conserved hypothetical protein 0.053 0.9987 1
Echinococcus granulosus integrin linked protein kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) TK/CSK protein kinase 0.053 0.9987 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0372 0.0331
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Echinococcus granulosus tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) LGC-31 protein 0.002 0.0252 0.0211
Schistosoma mansoni protein kinase 0.0531 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0255 0.0092
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0031
Schistosoma mansoni DNA helicase recq1 0.0031 0.0459 0.0449
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0721 0.0682
Echinococcus granulosus activin receptor type 0.0531 1 1
Onchocerca volvulus 0.002 0.0252 0.0211
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0484 0.9101 0.9108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0045 0.0719 0.0564
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0073 0.0031
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis CAMK family protein kinase 0.053 0.9987 1
Schistosoma mansoni ferritin 0.0009 0.0039 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0511 0.0471
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0274 0.0263
Loa Loa (eye worm) RGC/RGC protein kinase 0.053 0.9987 1
Entamoeba histolytica serine/threonine kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.053 0.9987 1
Onchocerca volvulus 0.053 0.9987 1
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Echinococcus granulosus insulin growth factor 1 receptor beta 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0252 0.0241
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0581 0.0514
Leishmania major protein kinase, putative 0.053 0.9987 0.9987
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.053 0.9987 1
Echinococcus multilocularis carbonyl reductase 1 0.0022 0.0291 0.0281
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0073 0.0031
Echinococcus granulosus nAChR subunit 0.0011 0.0073 0.0061
Giardia lamblia DINP protein human, muc B family 0.0023 0.0302 0.0049
Brugia malayi hypothetical protein 0.0022 0.0274 0.0233
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/KIN6 protein kinase 0.053 0.9987 1
Entamoeba histolytica tyrosin kinase, putative 0.053 0.9987 0.9987
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0459 0.021
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Onchocerca volvulus 0.002 0.0252 0.0211
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.284 1
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0511 0.0443
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.1596 0.1587
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) RecQ helicase 0.0045 0.0721 0.0682
Trichomonas vaginalis protein kinase atn1, putative 0.053 0.9987 1
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0531 1 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0667 0.0423
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0459 0.0449
Trichomonas vaginalis conserved hypothetical protein 0.053 0.9987 1
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.053 0.9987 0.9987
Onchocerca volvulus 0.053 0.9987 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.002 0.0252 0.0241
Entamoeba histolytica hypothetical protein 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0167 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Brugia malayi nuclear hormone receptor 0.0011 0.0073 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.053 0.9987 0.9987
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0073 0.0031
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.9987 0.9987
Echinococcus multilocularis tyrosine protein kinase Src42A 0.053 0.9987 0.9987
Echinococcus granulosus dna polymerase eta 0.0016 0.0164 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0073 0.0031
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Echinococcus granulosus c src tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0016 0.0164 0.0153
Echinococcus granulosus tyrosine protein kinase Btk29A 0.053 0.9987 0.9987
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0011 0.0073 0.0061
Echinococcus multilocularis insulin receptor 0.053 0.9987 0.9987
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0009 0.0042 0.0031
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.053 0.9987 0.9987
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase Srms 0.053 0.9987 0.9987
Brugia malayi nuclear receptor NHR-88 0.0011 0.0073 0.0031
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.035 0.0259
Schistosoma mansoni rab6-interacting 0.0022 0.0274 0.0263
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Echinococcus granulosus tyrosine protein kinase csk 0.053 0.9987 0.9987
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.053 0.9987 1
Onchocerca volvulus 0.053 0.9987 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Entamoeba histolytica cysteine surface protein, putative 0.053 0.9987 0.9987
Brugia malayi integrin-linked kinase 0.053 0.9987 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.0252 0.0211
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Echinococcus granulosus tyrosine protein kinase HCK 0.053 0.9987 0.9987
Onchocerca volvulus 0.053 0.9987 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0073 0.0031
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Echinococcus multilocularis tyrosine protein kinase csk 0.053 0.9987 0.9987
Schistosoma mansoni lipoxygenase 0.009 0.1582 0.1573
Schistosoma mansoni nAChR subunit 0.002 0.0252 0.0241
Onchocerca volvulus Putative nachr subunit 0.002 0.0252 0.0211
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0073 0.0062
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0459 0.0369
Treponema pallidum fructose-bisphosphate aldolase 0.0319 0.5958 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0073 0.0062
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.053 0.9987 0.9987
Trypanosoma cruzi short chain dehydrogenase, putative 0.0027 0.0372 0.0211
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0302 0.014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0073 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0073 0.0031
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.053 0.9987 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0531 1 1
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Entamoeba histolytica protein kinase domain containing protein 0.0531 1 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.053 0.9987 1
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0155 0.0083
Echinococcus granulosus retinal guanylyl cyclase 2 0.053 0.9987 0.9987
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0255 0.0244
Onchocerca volvulus 0.053 0.9987 1
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0372 0.0361
Schistosoma mansoni protein kinase 0.053 0.9987 0.9987
Brugia malayi Raf kinase 0.053 0.9987 1
Onchocerca volvulus 0.053 0.9987 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0073 0.0062
Echinococcus granulosus tyrosine protein kinase Src64B 0.053 0.9987 0.9987
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0274 0.0263
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Schistosoma mansoni carbonyl reductase 0.0027 0.0372 0.0361
Echinococcus granulosus retinal guanylyl cyclase 2 0.053 0.9987 0.9987
Echinococcus granulosus kinase suppressor of Ras 1 0.053 0.9987 0.9987
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.053 0.9987 0.9987
Echinococcus multilocularis Protein lozenge 0.0061 0.1021 0.1011
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Brugia malayi CXXC zinc finger family protein 0.0031 0.0461 0.0421
Entamoeba histolytica hypothetical protein 0.0026 0.035 0.028
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0252 0.0241
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0073 0.0031
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.0252 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0073 0.0031
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Loa Loa (eye worm) GABA receptor subunit 0.0011 0.0073 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0208 0.0139
Trypanosoma brucei Flagellum attachment zone protein 20 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/RYK protein kinase 0.053 0.9987 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.5958 0.595
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.0252 0.0241
Giardia lamblia Fructose-bisphosphate aldolase 0.0319 0.5958 0.586
Echinococcus multilocularis fibroblast growth factor receptor 4 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.9987 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.053 0.9987 0.9987
Schistosoma mansoni ferritin light chain 0.0009 0.0039 0.0028
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0042 0.0031
Echinococcus multilocularis tyrosine protein kinase pr2 0.053 0.9987 0.9987
Loa Loa (eye worm) TK/EPH protein kinase 0.053 0.9987 1
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Echinococcus granulosus protein tyrosine kinase 0.053 0.9987 0.9987
Trichomonas vaginalis conserved hypothetical protein 0.053 0.9987 1
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.003
Loa Loa (eye worm) hypothetical protein 0.002 0.0252 0.0211
Schistosoma mansoni tyrosine kinase 0.053 0.9987 0.9987
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0252 0.0211
Entamoeba histolytica serine/threonine kinase, putative 0.053 0.9987 0.9987
Onchocerca volvulus 0.0091 0.1596 0.1563
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica tyrosine kinase, putative 0.053 0.9987 0.9987
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0255 0.0214
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.035 0.0198
Entamoeba histolytica protein kinase, putative 0.053 0.9987 0.9987
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0511 0.0443
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.053 0.9987 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0164 0.0578
Onchocerca volvulus 0.053 0.9987 1
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.053 0.9987 0.9987
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.002 0.0252 0.0241
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0274 0.0263
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0039 0.0138
Echinococcus multilocularis carbonyl reductase 1 0.0027 0.0372 0.0361
Loa Loa (eye worm) SRC-1 0.053 0.9987 1
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Echinococcus multilocularis integrin linked protein kinase 0.053 0.9987 0.9987
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.1239 0.1177
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0073 0.0031
Trichomonas vaginalis TKL family protein kinase 0.053 0.9987 1
Entamoeba histolytica protein kinase domain containing protein 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Plasmodium falciparum protein kinase, putative 0.0531 1 1
Entamoeba histolytica hypothetical protein, conserved 0.053 0.9987 0.9987
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.053 0.9987 0.9987
Plasmodium vivax tyrosine kinase-like protein, putative 0.053 0.9987 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.053 0.9987 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.002 0.0252 0.0241
Schistosoma mansoni neurotransmitter gated ion channel 0.0009 0.0042 0.0031
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0073 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0719 0.0653
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.053 0.9987 0.9987
Schistosoma mansoni nAChR subunit 0.0009 0.0042 0.0031
Loa Loa (eye worm) hypothetical protein 0.053 0.9987 1
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0274 0.0019
Echinococcus multilocularis tyrosine protein kinase csk 0.053 0.9987 0.9987
Brugia malayi Protein kinase domain containing protein 0.053 0.9987 1
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.035 0.1233
Echinococcus granulosus activated cdc42 kinase 1 0.053 0.9987 0.9987
Echinococcus multilocularis RUN 0.0022 0.0274 0.0263
Echinococcus granulosus tyrosine protein kinase csk 0.053 0.9987 0.9987

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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