Detailed information for compound 1881586

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 617.173 | Formula: C33H45ClN2O7
  • H donors: 0 H acceptors: 2 LogP: 4.45 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C1O[C@@H](c2ccoc2)[C@]2(C(=C1)[C@]1(C)/C(=N\OCCN3CCCCC3)/C[C@@H]3[C@]4([C@H]1CC2)COC(=O)C[C@@H]4OC3(C)C)C.Cl
  • InChi: 1S/C33H44N2O7.ClH/c1-30(2)23-16-25(34-40-15-13-35-11-6-5-7-12-35)32(4)22(33(23)20-39-27(36)18-26(33)42-30)8-10-31(3)24(32)17-28(37)41-29(31)21-9-14-38-19-21;/h9,14,17,19,22-23,26,29H,5-8,10-13,15-16,18,20H2,1-4H3;1H/b34-25-;/t22-,23-,26-,29-,31+,32+,33+;/m0./s1
  • InChiKey: ABSONOSEEYVRNK-XTEOCRCGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni amine GPCR 0.0012 0.0014 0.0022
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0014 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0007 0.0038
Onchocerca volvulus 0.0012 0.0014 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0014 0.0022
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0007 0.0001
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni biogenic amine receptor 0.0012 0.0014 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0032 0.0228 0.3419
Echinococcus granulosus allatostatin A receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0099 0.0562
Plasmodium vivax ataxin-2 like protein, putative 0.0019 0.0089 0.3802
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.003 0.0206 0.5945
Brugia malayi follicle stimulating hormone receptor 0.0148 0.1482 0.8393
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0014 0.0043
Brugia malayi Serotonin receptor 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0134 0.0756
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0007 0.0001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0014 0.008
Onchocerca volvulus 0.0012 0.0014 0.0043
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Brugia malayi hypothetical protein 0.0019 0.0089 0.0503
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.003 0.0206 0.315
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0014 0.0008
Brugia malayi Dopamine receptor protein 1 0.0012 0.0014 0.008
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Leishmania major phosphopantetheinyl transferase-like protein 0.0032 0.0223 0.3422
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0096 0.0915 0.5177
Echinococcus granulosus muscleblind protein 0.0114 0.1114 0.116
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0033 0.0233 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0007 0.0038
Echinococcus granulosus neuropeptide receptor A26 0.0895 0.9555 1
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0014 0.0008
Echinococcus granulosus mitogen activated protein kinase 0.003 0.0206 0.0209
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.003 0.0208 0.1176
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus granulosus lamin 0.0021 0.0103 0.0101
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0014 0.0022
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0638 0.0632
Schistosoma mansoni amine GPCR 0.0012 0.0014 0.0022
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0014 0.0008
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0293 0.013
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0014 0.0008
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.003 0.0206 0.1384
Brugia malayi G protein-coupled receptor 0.0012 0.0014 0.008
Schistosoma mansoni zinc finger protein 0.0012 0.0007 0.0001
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0014 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.1151
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0014 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0019 0.0089 0.3802
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0014 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0007 0.0038
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis lamin dm0 0.0021 0.0103 0.0097
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0014 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0007 0.0038
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0014 0.0022
Toxoplasma gondii isocitrate dehydrogenase 0.003 0.0208 0.1412
Onchocerca volvulus 0.0012 0.0014 0.0043
Brugia malayi Latrophilin receptor protein 2 0.003 0.0208 0.1176
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0027 0.0177 0.0179
Trichomonas vaginalis CMGC family protein kinase 0.003 0.0206 0.2791
Onchocerca volvulus 0.0012 0.0014 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.003 0.0208 0.6017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus granulosus somatostatin receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0013 0.0022 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Echinococcus multilocularis muscleblind protein 0.0114 0.1114 0.1109
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0014 0.0008
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.003 0.0208 0.0211
Loa Loa (eye worm) hypothetical protein 0.0096 0.0915 0.5177
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0014 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0203 0.2714
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0014 0.0008
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0342 0.0335
Schistosoma mansoni hypothetical protein 0.0325 0.3395 1
Brugia malayi Heterochromatin protein 1 0.0053 0.0456 0.2582
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0014 0.0022
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0007 0.0038
Schistosoma mansoni amine GPCR 0.0012 0.0014 0.0022
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.003 0.0206 0.5945
Schistosoma mansoni biogenic amine receptor 0.0012 0.0014 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0113 0.1098 0.6217
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0014 0.0008
Schistosoma mansoni hypothetical protein 0.0012 0.0014 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0007 0.0038
Brugia malayi chromobox protein homolog 3 0.003 0.0203 0.1151
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0007 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0007 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0638 0.1865
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0014 0.0008
Brugia malayi G-protein coupled receptor 0.0012 0.0014 0.008
Onchocerca volvulus 0.0012 0.0014 0.0043
Schistosoma mansoni hypothetical protein 0.003 0.0208 0.0594
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0014 0.0022
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0017 0.0067 0.006
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0007 0.0038
Onchocerca volvulus 0.0012 0.0014 0.0043
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0014 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0007 0.0038
Brugia malayi putative neuropeptide receptor 0.0012 0.0014 0.008
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.003 0.0208 0.0596
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis chromobox protein 1 0.0053 0.0456 0.045
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0007 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0014 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0013 0.0022 0.0044
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis serotonin receptor 0.0012 0.0014 0.0008
Brugia malayi Intermediate filament tail domain containing protein 0.0021 0.0103 0.0585
Onchocerca volvulus 0.0012 0.0014 0.0043
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0097 0.0935 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0032 0.0228 0.1257
Brugia malayi Calcitonin receptor-like protein seb-1 0.0096 0.0915 0.5177
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0046 0.0374 0.0385
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0032 0.0223 0.0027
Loa Loa (eye worm) heterochromatin protein 1 0.0053 0.0456 0.2582
Echinococcus multilocularis isocitrate dehydrogenase 0.003 0.0208 0.0202
Schistosoma mansoni lipoxygenase 0.0033 0.0233 0.0669
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Onchocerca volvulus 0.0012 0.0014 0.0043
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Trichomonas vaginalis CMGC family protein kinase 0.003 0.0206 0.2791
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0208 0.0202
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni methyl-cpg binding protein mbd 0.0013 0.0022 0.0044
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0014 0.0022
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0014 0.0008
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0032 0.0223 1
Echinococcus granulosus hypothetical protein 0.0012 0.0014 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Echinococcus multilocularis geminin 0.0325 0.3395 0.3391
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0113 0.1098 0.3222
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Echinococcus granulosus neuropeptide s receptor 0.0895 0.9555 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0014 0.0008
Schistosoma mansoni histamine h1 receptor 0.0012 0.0014 0.0022
Echinococcus multilocularis neuropeptide receptor A26 0.0895 0.9555 0.9555
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0014 0.008
Onchocerca volvulus 0.0023 0.0134 0.0722
Brugia malayi larval opioid receptor 0.0012 0.0014 0.008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0007 0.0038
Echinococcus multilocularis mitogen activated protein kinase 3 0.003 0.0206 0.02
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni amine GPCR 0.0012 0.0014 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.003 0.0206 0.5945
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0148 0.1482 0.8393
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0208 0.3188
Trichomonas vaginalis CMGC family protein kinase 0.003 0.0206 0.2791
Schistosoma mansoni neuropeptide receptor 0.0012 0.0014 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0007 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0114 0.1114 0.631
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0007 0.0038
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0014 0.0008
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0014 0.0008
Brugia malayi MH2 domain containing protein 0.0138 0.137 0.7759
Toxoplasma gondii isocitrate dehydrogenase 0.003 0.0208 0.1412
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus granulosus intermediate filament protein 0.0021 0.0103 0.0101
Brugia malayi Dopamine receptor 0.0012 0.0014 0.008
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0013 0.0022 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0014 0.0008
Echinococcus granulosus g protein coupled receptor 0.0012 0.0014 0.0008
Schistosoma mansoni neuropeptide receptor 0.0012 0.0014 0.0022
Echinococcus multilocularis sex peptide receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0217 0.1229
Echinococcus multilocularis lamin 0.0021 0.0103 0.0097
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.003 0.0208 0.0201
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0007 0.0001
Brugia malayi isocitrate dehydrogenase 0.003 0.0208 0.1179
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0014 0.008
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0014 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0206 0.0589
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0007 0.0038
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0014 0.0022
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0014 0.0008
Echinococcus granulosus serotonin receptor 0.0012 0.0014 0.0008
Treponema pallidum licC protein (licC) 0.0097 0.0935 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0532 0.5629 1
Giardia lamblia Kinase, CMGC MAPK 0.003 0.0206 0.5
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.003 0.0206 0.315
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0014 0.0022
Echinococcus granulosus chromobox protein 1 0.0053 0.0456 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0203 0.2714
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Brugia malayi Bromodomain containing protein 0.0029 0.0197 0.1115
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0014 0.008
Onchocerca volvulus 0.0021 0.0103 0.0551
Loa Loa (eye worm) intermediate filament protein 0.0021 0.0103 0.0585
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0037
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni opsin-like receptor 0.0012 0.0014 0.0022
Onchocerca volvulus 0.0012 0.0014 0.0043
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.003 0.0208 0.0202
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0532 0.5629 1
Brugia malayi G-protein coupled receptor 0.0012 0.0014 0.008
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0007 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0014 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0638 0.0768
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Brugia malayi nuclear receptor NHR-88 0.0012 0.0007 0.0038
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0456 1
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0037
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0014 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0007 0.0038
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0342 1
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0014 0.0008
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0768 0.8183 0.8182
Onchocerca volvulus 0.0012 0.0014 0.0043
Echinococcus granulosus g protein coupled receptor 0.0012 0.0014 0.0008
Brugia malayi RE15519p 0.0012 0.0014 0.008
Trypanosoma brucei protein kinase, putative 0.003 0.0206 0.5945
Onchocerca volvulus 0.0113 0.1098 0.6203
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0014 0.008
Brugia malayi ORL1-like opioid receptor 0.0012 0.0014 0.008
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis L aminoadipate semialdehyde 0.0113 0.1098 0.1092
Brugia malayi Muscleblind-like protein 0.0114 0.1114 0.631
Trichomonas vaginalis CMGC family protein kinase 0.003 0.0206 0.2791
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus granulosus fetal alzheimer antigen falz 0.0017 0.0067 0.0063
Brugia malayi neuropeptide F receptor 0.0012 0.0014 0.008
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.003 0.0206 0.5945
Schistosoma mansoni hypothetical protein 0.003 0.0208 0.0594
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0017 0.0067 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni hypothetical protein 0.0012 0.0014 0.0022
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0014 0.0022
Onchocerca volvulus 0.0012 0.0014 0.0043
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0014 0.0022
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0014 0.0022
Plasmodium falciparum ataxin-2 like protein, putative 0.0019 0.0089 0.3802
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0638 0.6497
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.003 0.0208 0.0211
Loa Loa (eye worm) doublecortin family protein 0.0012 0.0007 0.0037
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0014 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0065 0.0587 0.3326
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0014 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0456 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.1098 0.6217
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0342 1
Brugia malayi sulfakinin receptor protein 0.0012 0.0014 0.008
Echinococcus multilocularis zinc finger protein 0.0015 0.0042 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Echinococcus multilocularis muscleblind protein 1 0.0114 0.1114 0.1109
Loa Loa (eye worm) bromodomain containing protein 0.0013 0.0027 0.0151
Loa Loa (eye worm) latrophilin receptor protein 2 0.003 0.0208 0.1176
Loa Loa (eye worm) hypothetical protein 0.0174 0.1766 1
Onchocerca volvulus 0.0012 0.0014 0.0043
Echinococcus granulosus orexin receptor type 2 0.0012 0.0014 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0138 0.137 0.7759
Schistosoma mansoni hypothetical protein 0.003 0.0208 0.0594
Echinococcus granulosus lamin dm0 0.0021 0.0103 0.0101
Mycobacterium ulcerans hypothetical protein 0.0097 0.0935 0.1316
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0768 0.8183 0.8563
Onchocerca volvulus 0.0012 0.0007 0.0001
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0014 0.008
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0007 0.0001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.003 0.0208 0.0201
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0007 0.0038
Brugia malayi Inositol-1 0.0043 0.0342 0.1934
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0021 0.0103 0.0585
Schistosoma mansoni chromobox protein 0.0053 0.0456 0.1327
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis serotonin receptor 0.0012 0.0014 0.0008
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0097 0.0935 0.1316
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0014 0.0008
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.003 0.0208 0.9319
Brugia malayi MAP kinase sur-1 0.003 0.0206 0.1166
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0007 0.0038
Loa Loa (eye worm) inositol-1 0.0043 0.0342 0.1934
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0007 0.0038
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0014 0.0008
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0014 0.008
Onchocerca volvulus 0.0021 0.0103 0.0551
Loa Loa (eye worm) hypothetical protein 0.003 0.0208 0.1176
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Echinococcus granulosus mitogen activated protein kinase 3 0.003 0.0206 0.0209
Schistosoma mansoni inositol monophosphatase 0.0043 0.0342 0.0989
Schistosoma mansoni neuropeptide receptor 0.0012 0.0014 0.0022
Echinococcus granulosus geminin 0.0325 0.3395 0.3549
Schistosoma mansoni lamin 0.0021 0.0103 0.0286
Schistosoma mansoni biogenic amine receptor 0.0012 0.0014 0.0022
Brugia malayi neuropeptide F receptor 0.0012 0.0014 0.008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0014 0.008
Schistosoma mansoni adenoreceptor 0.0012 0.0014 0.0022
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0014 0.0008
Echinococcus multilocularis GPCR, family 2 0.003 0.0208 0.0201
Brugia malayi AKH receptor 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Brugia malayi hypothetical protein 0.0012 0.0015 0.0085
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0007 0.0038
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0014 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0014 0.0022
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0638 1
Loa Loa (eye worm) hypothetical protein 0.0114 0.1114 0.631
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0014 0.008
Schistosoma mansoni neuropeptide receptor 0.0012 0.0014 0.0022
Brugia malayi Doublecortin family protein 0.0012 0.0007 0.0037
Schistosoma mansoni hypothetical protein 0.0016 0.0051 0.0132
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0342 0.0351
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0208 0.0202
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0014 0.0022
Schistosoma mansoni myosin xvIII 0.0012 0.0014 0.0022
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0007 0.0001
Onchocerca volvulus 0.0012 0.0014 0.0043
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0032 0.0223 0.1587
Brugia malayi ecdysteroid receptor 0.0012 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0014 0.0008
Brugia malayi Serotonin receptor 0.0012 0.0014 0.008
Echinococcus multilocularis neuropeptide s receptor 0.0895 0.9555 0.9555
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.0089 0.2446
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0014 0.008
Onchocerca volvulus Heterochromatin protein 1 homolog 0.003 0.0203 0.1118
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0096 0.0915 0.5177
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0014 0.0008
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0007 0.0001
Onchocerca volvulus 0.0012 0.0014 0.0043
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0032 0.0223 0.5
Brugia malayi Dopamine receptor protein 2 0.0012 0.0014 0.008
Schistosoma mansoni bromodomain containing protein 0.0048 0.0403 0.1171
Brugia malayi hypothetical protein 0.0012 0.0007 0.0037
Leishmania major hypothetical protein, conserved 0.0019 0.0089 0.1296
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0014 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.0089 0.2446
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0014 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0013 0.0022 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0007 0.0038
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.003 0.0206 0.1166
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni inositol monophosphatase 0.0043 0.0342 0.0989
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Trichomonas vaginalis chromobox protein, putative 0.0032 0.0228 0.3419
Brugia malayi Melatonin receptor type 1A 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni coup transcription factor 0.0012 0.0007 0.0001
Brugia malayi intermediate filament protein 0.0021 0.0103 0.0585
Echinococcus granulosus L aminoadipate semialdehyde 0.0113 0.1098 0.1143
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Trypanosoma brucei PAB1-binding protein , putative 0.0019 0.0089 0.2446
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0293 0.0157
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0638 0.0793
Mycobacterium ulcerans hypothetical protein 0.0097 0.0935 0.1316
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0342 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0122
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0198 0.1119
Onchocerca volvulus 0.0012 0.0014 0.0043
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0014 0.0022
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Schistosoma mansoni hypothetical protein 0.0012 0.0014 0.0022
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0014 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0585
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.0935 0.134
Loa Loa (eye worm) isocitrate dehydrogenase 0.003 0.0208 0.1179
Brugia malayi PHD-finger family protein 0.0019 0.0086 0.0489
Brugia malayi nuclear hormone receptor 0.0012 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni chromobox protein 0.0053 0.0456 0.1327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0638 0.0768
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0014 0.008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0342 0.67
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0342 0.0219
Schistosoma mansoni intermediate filament proteins 0.0021 0.0103 0.0286
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.003 0.0208 0.9319
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0014 0.0008
Brugia malayi steroid hormone receptor 0.0012 0.0007 0.0038
Schistosoma mansoni hypothetical protein 0.003 0.0208 0.0594
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0208 0.6017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0014 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0089 0.0503
Trypanosoma brucei isocitrate dehydrogenase, putative 0.003 0.0208 0.6017
Brugia malayi hypothetical protein 0.0012 0.0007 0.0037
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0038
Loa Loa (eye worm) PHD-finger family protein 0.0016 0.0051 0.0289
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0014 0.008
Brugia malayi GnHR receptor homolog 0.0012 0.0014 0.008
Schistosoma mansoni hypothetical protein 0.0065 0.0587 0.1714
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0014 0.008
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0014 0.0008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0342 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0342 0.0219
Echinococcus granulosus histone lysine methyltransferase setb 0.0013 0.0022 0.0016
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0342 0.5299
Schistosoma mansoni hypothetical protein 0.0325 0.3395 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0638 0.0662
Echinococcus granulosus g protein coupled receptor 0.0012 0.0014 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0342 0.2988
Echinococcus granulosus GPCR family 2 0.003 0.0208 0.0211
Schistosoma mansoni amine GPCR 0.0012 0.0014 0.0022
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0014 0.0008
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Echinococcus multilocularis somatostatin receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Echinococcus granulosus chromobox protein 1 0.0053 0.0456 0.0471
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0007 0.0001
Echinococcus granulosus methyl CpG binding domain protein 2 0.0013 0.0022 0.0016
Schistosoma mansoni hypothetical protein 0.0012 0.0014 0.0022
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0208 0.0202
Echinococcus multilocularis chromobox protein 1 0.0053 0.0456 0.045
Echinococcus granulosus neuropeptide receptor 0.0012 0.0014 0.0008
Onchocerca volvulus 0.0174 0.1766 1
Echinococcus multilocularis mitogen activated protein kinase 0.003 0.0206 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0032 0.0223 0.1587
Schistosoma mansoni opsin-like receptor 0.0012 0.0014 0.0022
Echinococcus granulosus zinc finger protein 0.0015 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0233 0.1319
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0027 0.0177 0.0171
Loa Loa (eye worm) hypothetical protein 0.0054 0.0465 0.2631
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0014 0.0008
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0638 0.0768
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0342 0.67
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0014 0.008
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0532 0.5629 1
Brugia malayi hypothetical protein 0.0012 0.0014 0.008
Echinococcus granulosus fmrfamide receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0014 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.0935 0.134
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0007 0.0001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0014 0.0008
Echinococcus multilocularis musashi 0.0021 0.0103 0.0097
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0208 0.6017
Brugia malayi Bromodomain containing protein 0.0057 0.05 0.2831
Loa Loa (eye worm) MH2 domain-containing protein 0.0138 0.137 0.7759
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Onchocerca volvulus 0.0012 0.0014 0.0043
Echinococcus granulosus sex peptide receptor 0.0012 0.0014 0.0008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0532 0.5629 1
Schistosoma mansoni opsin-like receptor 0.0012 0.0014 0.0022
Brugia malayi latrophilin 2 splice variant baaae 0.0065 0.0587 0.3326
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0014 0.0008
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.003 0.0208 0.0211
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0032 0.0223 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.003 0.0206 0.5945
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0046 0.0374 0.0367
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0342 0.67
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.008
Schistosoma mansoni lamin 0.0021 0.0103 0.0286
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0007 0.0038
Brugia malayi hypothetical protein 0.0174 0.1766 1
Schistosoma mansoni zinc finger protein 0.0015 0.0042 0.0106
Onchocerca volvulus 0.0012 0.0014 0.0043
Brugia malayi Isocitrate dehydrogenase 0.003 0.0208 0.1179
Trypanosoma brucei hypothetical protein, conserved 0.0032 0.0223 0.6458
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0014 0.0008
Echinococcus granulosus neuropeptide receptor 0.0012 0.0014 0.0008
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0014 0.008
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0014 0.008
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0638 0.1865
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0033 0.0233 0.0237
Schistosoma mansoni hypothetical protein 0.0012 0.0007 0.0001
Schistosoma mansoni methyl-cpg binding protein mbd 0.0013 0.0022 0.0044

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 44.32 % Analgesic activity in mouse assessed as inhibition of acetic acid-induced writhing at 70 mg/kg, ig administered 1 hr before acetic acid challenge measured after 15 mins ChEMBL. 24569111

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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