Detailed information for compound 20237

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 577.714 | Formula: C32H43N5O5
  • H donors: 3 H acceptors: 4 LogP: 2.89 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(C[C@@H]1C(=O)N2CCCC2[C@@]2(N1C(=O)[C@](O2)(NC(=O)C1CN(C)C2C(C1)c1cccc3c1c(C2)c[nH]3)C(C)C)O)C
  • InChi: 1S/C32H43N5O5/c1-17(2)12-25-29(39)36-11-7-10-26(36)32(41)37(25)30(40)31(42-32,18(3)4)34-28(38)20-13-22-21-8-6-9-23-27(21)19(15-33-23)14-24(22)35(5)16-20/h6,8-9,15,17-18,20,22,24-26,33,41H,7,10-14,16H2,1-5H3,(H,34,38)/t20?,22?,24?,25-,26?,31+,32-/m0/s1
  • InChiKey: PBUNVLRHZGSROC-ACVFXLHMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cpg binding protein 0.003 0.0146 0.0146
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Brugia malayi FAD binding domain containing protein 0.003 0.0144 0.0237
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0091 0.0282
Loa Loa (eye worm) beta-lactamase 0.004 0.0216 0.0355
Chlamydia trachomatis sulfite reductase 0.0018 0.0059 0.0185
Trichomonas vaginalis abcb9, putative 0.0013 0.0017 0.0041
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0019 0.005
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.0236 0.1665 0.274
Echinococcus multilocularis importin 5 0.0011 0.0007 0.0007
Brugia malayi nuclear hormone receptor 0.002 0.0069 0.0114
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0069 0.0069
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.018 0.018
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0201 0.1405 0.2312
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.003 0.0144 0.0545
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0285 0.0457
Brugia malayi Trypsin family protein 0.0236 0.1665 0.274
Toxoplasma gondii malate dehydrogenase MDH 0.0833 0.6076 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0017 0.0041
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.0324 0.2315 0.8991
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0013 0.0019 0.0019
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0285 0.0285
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0048 0.008
Brugia malayi glutathione reductase 0.0141 0.0968 0.1592
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus granulosus glycoprotein Antigen 5 0.0236 0.1665 0.1665
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.003 0.0144 0.0592
Echinococcus granulosus malate dehydrogenase 0.0324 0.2315 0.2315
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0013 0.0019 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0216 0.0905
Schistosoma mansoni multidrug resistance protein 0.0013 0.0017 0.0017
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0216 0.078
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0013 0.0019 0.005
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0013 0.0019 0.0019
Leishmania major NADH dehydrogenase, putative 0.0013 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Brugia malayi Trypsin family protein 0.0236 0.1665 0.274
Trypanosoma brucei mitochondrial malate dehydrogenase 0.0324 0.2315 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0155 0.1069 0.4576
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0069 0.0114
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0032 0.0156 0.0644
Mycobacterium tuberculosis Conserved protein 0.004 0.0216 0.078
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0252 0.1063
Schistosoma mansoni ran 0.0045 0.0252 0.0252
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.003 0.0144 0.0592
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0069 0.0069
Toxoplasma gondii lactate dehydrogenase LDH2 0.0833 0.6076 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0285 0.1049
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0013 0.0017 0.0015
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0064 0.0105
Loa Loa (eye worm) hypothetical protein 0.0201 0.1405 0.2312
Mycobacterium ulcerans hypothetical protein 0.0236 0.1665 0.7171
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0069 0.0069
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0064 0.0064
Plasmodium vivax thioredoxin reductase, putative 0.0141 0.0968 0.1582
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0216 0.0355
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0048 0.0068
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0017 0.0041
Onchocerca volvulus 0.0236 0.1665 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0069 0.0114
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Echinococcus granulosus geminin 0.0187 0.1303 0.1303
Brugia malayi beta-lactamase 0.004 0.0216 0.0355
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0064 0.0246
Onchocerca volvulus 0.0236 0.1665 1
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.0936 0.154
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0324 0.2315 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0142 0.0971 0.0971
Echinococcus multilocularis methionine synthase reductase 0.0018 0.0059 0.0059
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0071 0.0451 0.1922
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Loa Loa (eye worm) hypothetical protein 0.0023 0.0091 0.0149
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0017 0.0017
Trichomonas vaginalis abcb9, putative 0.0013 0.0017 0.0041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0408 0.0408
Onchocerca volvulus 0.0236 0.1665 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0069 0.0114
Echinococcus granulosus malate dehydrogenase 0.0324 0.2315 0.2315
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.0019 0.005
Mycobacterium tuberculosis Probable dehydrogenase 0.0323 0.2306 0.8959
Loa Loa (eye worm) hypothetical protein 0.0063 0.0392 0.0644
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.1203
Schistosoma mansoni NADPH flavin oxidoreductase 0.0015 0.0034 0.0034
Brugia malayi RNA, U transporter 1 0.0172 0.1197 0.1971
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0017 0.0017
Plasmodium vivax flavodoxin domain containing protein 0.0027 0.0119 0.0184
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.0457
Onchocerca volvulus 0.002 0.0069 0.0319
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0069 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0062 0.038 0.038
Echinococcus multilocularis Mastin 0.0236 0.1665 0.1665
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0386 0.1641
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0013 0.0017 0.0015
Echinococcus multilocularis cpg binding protein 0.0032 0.0159 0.0159
Trypanosoma brucei glycosomal malate dehydrogenase 0.0324 0.2315 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0019 0.0019
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0286 0.1209
Leishmania major hypothetical protein, conserved 0.0013 0.0019 0.0019
Echinococcus multilocularis tumor protein p63 0.0373 0.2676 0.2676
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0285 0.0439
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0017 0.0017
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0071 0.0451 0.0451
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.1203
Mycobacterium tuberculosis Probable malate dehydrogenase Mdh 0.0324 0.2315 0.8992
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.008
Leishmania major hypothetical protein, conserved 0.004 0.0216 0.0344
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0069 0.0069
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0216 0.0216
Leishmania major cytosolic malate dehydrogenase 0.0324 0.2315 0.3802
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0069 0.0069
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0146 0.0241
Schistosoma mansoni coup transcription factor 0.002 0.0069 0.0069
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0069 0.0069
Loa Loa (eye worm) importin-beta domain-containing protein 0.0011 0.0007 0.0012
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.003 0.0144 0.0144
Loa Loa (eye worm) glutathione reductase 0.0141 0.0968 0.1592
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0854 0.6238 0.6238
Brugia malayi Muscleblind-like protein 0.0451 0.3257 0.536
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0048 0.0068
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0017 0.0041
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0392 0.0644
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0451 0.3257 0.536
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Schistosoma mansoni hypothetical protein 0.0063 0.0392 0.0392
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0371 0.0599
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0324 0.2315 1
Trichomonas vaginalis esterase, putative 0.004 0.0216 0.0905
Plasmodium falciparum glutathione reductase 0.0049 0.0285 0.0457
Echinococcus granulosus lactate dehydrogenase a 0.0833 0.6076 0.6076
Loa Loa (eye worm) flavodoxin family protein 0.0011 0.0007 0.0012
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.0019 0.005
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Mycobacterium ulcerans putative regulatory protein 0.0023 0.0091 0.0314
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0013 0.0017 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0048 0.008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0069 0.0069
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0216 0.0905
Plasmodium falciparum nitric oxide synthase, putative 0.003 0.0144 0.0225
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.0237
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0285 0.1159
Entamoeba histolytica P-glycoprotein-1 0.0013 0.0017 0.0016
Brugia malayi CXXC zinc finger family protein 0.003 0.0146 0.0241
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0216 0.0905
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.003 0.0144 0.0592
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0013 0.0019 0.0019
Trypanosoma brucei malate dehydrogenase-related 0.0324 0.2315 1
Leishmania major trypanothione reductase 0.0141 0.0968 0.1582
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0201 0.1405 0.2312
Echinococcus multilocularis thioredoxin glutathione reductase 0.0142 0.0971 0.0971
Plasmodium vivax ferrodoxin reductase, putative 0.0013 0.0019 0.0019
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0017 0.0017
Leishmania major hypothetical protein, conserved 0.0017 0.0048 0.0068
Loa Loa (eye worm) RNA binding protein 0.0062 0.038 0.0625
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0069 0.0319
Echinococcus granulosus transportin 1 0.0011 0.0007 0.0007
Brugia malayi Malate dehydrogenase, cytoplasmic 0.0324 0.2315 0.3809
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0069 0.0114
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.008
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0048 0.0048
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0013 0.0019 0.0008
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.038 0.0625
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0236 0.1665 0.274
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0069 0.0114
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0285 0.0439
Schistosoma mansoni glutamate synthase 0.0013 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0833 0.6076 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0049 0.0285 0.1166
Mycobacterium leprae conserved hypothetical protein 0.004 0.0216 0.0773
Entamoeba histolytica P-glycoprotein-2 0.0013 0.0017 0.0016
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0069 0.0114
Trypanosoma brucei cytosolic malate dehydrogenase 0.0324 0.2315 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0069 0.0114
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0048 0.0048
Echinococcus granulosus translational activator gcn1 0.0011 0.0007 0.0007
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0346 0.0558
Toxoplasma gondii GAF domain-containing protein 0.0023 0.0091 0.0138
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0017 0.0041
Echinococcus multilocularis malate dehydrogenase 0.0324 0.2315 0.2315
Schistosoma mansoni glutamate synthase 0.0013 0.0019 0.0019
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0048 0.0048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0013 0.0019 0.0019
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0324 0.2315 1
Schistosoma mansoni hypothetical protein 0.0187 0.1303 0.1303
Leishmania major GTP-binding protein, putative 0.0045 0.0252 0.0404
Entamoeba histolytica disulphide oxidoreductase, putative 0.0013 0.0019 0.0019
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Onchocerca volvulus 0.0013 0.0019 0.0012
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0064 0.0093
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0013 0.0019 0.0019
Toxoplasma gondii hypothetical protein 0.0023 0.0091 0.0138
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0013 0.0019 0.0019
Onchocerca volvulus 0.0236 0.1665 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Entamoeba histolytica hypothetical protein 0.0035 0.018 0.0285
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Mycobacterium ulcerans putative regulatory protein 0.0023 0.0091 0.0314
Treponema pallidum oxidoreductase 0.0013 0.0019 0.0051
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Brugia malayi ABC transporter family protein 0.0013 0.0017 0.0027
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0019 0.0031
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0069 0.0069
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0032 0.0156 0.0156
Brugia malayi Trypsin-like protease protein 5 0.0236 0.1665 0.274
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Echinococcus granulosus cpg binding protein 0.0032 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0031
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0013 0.0019 0.005
Leishmania major malate dehydrogenase, putative 0.0833 0.6076 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0392 0.0392
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0019 0.005
Mycobacterium ulcerans lipase LipD 0.004 0.0216 0.0859
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0019 0.0019
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.003 0.0144 0.0225
Trypanosoma cruzi malate dehydrogenase, putative 0.0324 0.2315 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0397 0.0397
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Entamoeba histolytica P-glycoprotein-5 0.0013 0.0017 0.0016
Brugia malayi Trypsin family protein 0.0236 0.1665 0.274
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0069 0.0114
Trichomonas vaginalis sulfite reductase, putative 0.003 0.0144 0.0592
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0359 0.2572 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0285 0.0457
Loa Loa (eye worm) hypothetical protein 0.0032 0.0156 0.0256
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0011 0.0007 0.0001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Echinococcus granulosus methionine synthase reductase 0.0018 0.0059 0.0059
Trichomonas vaginalis apoptosis inducing factor, putative 0.0013 0.0019 0.005
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.0395 0.0395
Echinococcus multilocularis GPCR, family 2 0.0063 0.0392 0.0392
Toxoplasma gondii flavodoxin domain-containing protein 0.0015 0.0032 0.0041
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0017 0.0017
Echinococcus granulosus cytosolic malate dehydrogenase 0.0324 0.2315 0.2315
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0286 0.1209
Trypanosoma cruzi trypanothione reductase, putative 0.0141 0.0968 0.4162
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0035 0.018 0.018
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Plasmodium vivax importin-beta 2, putative 0.0061 0.0371 0.0599
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0285 0.0457
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0019 0.0019
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0252 0.0404
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0064 0.0246
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0019 0.005
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0285 0.0468
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0285 0.1203
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0236 0.1665 0.1665
Brugia malayi FAD binding domain containing protein 0.0018 0.0059 0.0097
Brugia malayi lactate dehydrogenase. 0.0833 0.6076 1
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0013 0.0019 0.005
Entamoeba histolytica hypothetical protein 0.0035 0.018 0.0285
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0069 0.0114
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0216 0.0216
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0017 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0386 0.1641
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0019 0.005
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.0019 0.005
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0032 0.0156 0.0156
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0069 0.0114
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.008
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0236 0.1665 0.1665
Plasmodium falciparum thioredoxin reductase 0.0141 0.0968 0.1582
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.003 0.0144 0.0592
Toxoplasma gondii thioredoxin reductase 0.0141 0.0968 0.1582
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0048 0.0048
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0323 0.2306 0.8959
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0064 0.0197
Schistosoma mansoni nuclear hormone receptor 0.002 0.0069 0.0069
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0061 0.0061
Echinococcus multilocularis lactate dehydrogenase a 0.0833 0.6076 0.6076
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0013 0.0019 0.0019
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0069 0.0069
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0371 0.1576
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0048 0.0048
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0013 0.0019 0.0008
Entamoeba histolytica thioredoxin reductase, putative 0.0013 0.0019 0.0019
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0285 0.0457
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0027
Echinococcus granulosus dnaJ subfamily B 0.0431 0.3108 0.3108
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0326 0.0326
Onchocerca volvulus 0.004 0.0216 0.1209
Echinococcus multilocularis ATP binding cassette sub family B 0.0013 0.0016 0.0016
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0285 0.0457
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0236 0.1665 0.274
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.0019 0.005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Schistosoma mansoni thyroid hormone receptor 0.002 0.0069 0.0069
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0285 0.1203
Loa Loa (eye worm) hypothetical protein 0.0236 0.1665 0.274
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0216 0.0905
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.227 0.3729
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.0395 0.0395
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0064 0.0246
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0064 0.0197
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0285 0.0285
Schistosoma mansoni hypothetical protein 0.0187 0.1303 0.1303
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Brugia malayi hypothetical protein 0.0236 0.1665 0.274
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0236 0.1665 0.1665
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0019 0.005
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.003 0.0144 0.0144
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0013 0.0019 0.0008
Loa Loa (eye worm) hypothetical protein 0.004 0.0216 0.0355
Echinococcus granulosus L lactate dehydrogenase 0.0509 0.3684 0.3684
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0061 0.0371 0.061
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0064 0.0093
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Loa Loa (eye worm) hypothetical protein 0.004 0.0216 0.0355
Brugia malayi Thioredoxin reductase 0.0141 0.0968 0.1592
Treponema pallidum NADH oxidase 0.0049 0.0285 0.1226
Leishmania major malate dehydrogenase, putative 0.0324 0.2315 0.3802
Echinococcus granulosus phd:f box containing protein 0.0017 0.0048 0.0048
Brugia malayi beta-lactamase family protein 0.004 0.0216 0.0355
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0019 0.005
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0019 0.0019
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0017 0.0017
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0049 0.0282 0.1193
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0285 0.0285
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0216 0.0859
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0216 0.0905
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0017 0.0041
Schistosoma mansoni diflavin oxidoreductase 0.0015 0.0032 0.0032
Toxoplasma gondii ABC1 family protein 0.004 0.0216 0.0344
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0013 0.0017 0.0027
Echinococcus granulosus snurportin 1 0.0648 0.4708 0.4708
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0013 0.0016 0.0016
Echinococcus multilocularis translational activator gcn1 0.0011 0.0007 0.0007
Trichomonas vaginalis taga, putative 0.0013 0.0017 0.0041
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0064 0.0093
Onchocerca volvulus 0.0236 0.1665 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0069 0.0114
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.038 0.0625
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0032 0.0156 0.0644
Plasmodium vivax JmjC domain containing protein 0.0017 0.0048 0.0068
Loa Loa (eye worm) hypothetical protein 0.004 0.0216 0.0355
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0019 0.005
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0285 0.1203
Mycobacterium tuberculosis Conserved protein 0.004 0.0216 0.078
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0017 0.0017
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0013 0.0019 0.0019
Brugia malayi flavodoxin family protein 0.0011 0.0007 0.0012
Mycobacterium ulcerans glutaminase 0.0272 0.1933 0.834
Trichomonas vaginalis malate dehydrogenase, putative 0.0158 0.1088 0.4684
Loa Loa (eye worm) malate dehydrogenase 0.0324 0.2315 0.3809
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.227 0.3729
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Leishmania major glycosomal malate dehydrogenase 0.0324 0.2315 0.3802
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0064 0.0093
Echinococcus granulosus muscleblind protein 0.0451 0.3257 0.3257
Schistosoma mansoni glutaminase 0.0272 0.1933 0.1933
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0017 0.0041
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0216 0.078
Loa Loa (eye worm) glutaminase 0.0272 0.1933 0.3182
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Echinococcus multilocularis muscleblind protein 0.0451 0.3257 0.3257
Schistosoma mansoni hypothetical protein 0.0063 0.0392 0.0392
Onchocerca volvulus 0.003 0.0146 0.0786
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0017 0.0017
Trypanosoma brucei NADH dehydrogenase 0.0013 0.0019 0.005
Schistosoma mansoni multidrug resistance protein 0.0013 0.0017 0.0017
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0019 0.0019
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.0324 0.2315 0.3802
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0324 0.2315 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.1203
Trypanosoma cruzi p450 reductase, putative 0.003 0.0144 0.0592
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0069 0.0069
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Brugia malayi TAR-binding protein 0.0062 0.038 0.0625
Schistosoma mansoni tar DNA-binding protein 0.0062 0.038 0.038
Schistosoma mansoni importin beta-1 0.0061 0.0371 0.0371
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0324 0.2315 1
Brugia malayi flavodoxin family protein 0.003 0.0144 0.0237
Plasmodium vivax hypothetical protein, conserved 0.004 0.0216 0.0344
Loa Loa (eye worm) hypothetical protein 0.004 0.0216 0.0355
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.0019 0.005
Echinococcus multilocularis tar DNA binding protein 0.0062 0.038 0.038
Schistosoma mansoni smdr2 0.0013 0.0017 0.0017
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0064 0.0105
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0252 0.1018
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0069 0.0114
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0013 0.0017 0.0041
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.003 0.0144 0.0225
Mycobacterium ulcerans beta-lactamase 0.004 0.0216 0.0859
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0188 0.031
Schistosoma mansoni ap endonuclease 0.0019 0.0064 0.0064
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0285 0.1203
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Schistosoma mansoni cpg binding protein 0.0032 0.0159 0.0159
Leishmania major p450 reductase, putative 0.003 0.0144 0.0225
Brugia malayi Calcitonin receptor-like protein seb-1 0.0201 0.1405 0.2312
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0285 0.1203
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0155 0.1069 0.4119
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0188 0.031
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0216 0.078
Brugia malayi jmjC domain containing protein 0.0066 0.0408 0.0671
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0069 0.0114
Loa Loa (eye worm) hypothetical protein 0.0236 0.1665 0.274
Giardia lamblia Fructose-bisphosphate aldolase 0.0318 0.227 0.9807
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.003 0.0144 0.0592
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0285 0.0457
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus multilocularis glycoprotein Antigen 5 0.0236 0.1665 0.1665
Plasmodium vivax glutathione reductase, putative 0.0141 0.0968 0.1582
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0013 0.0019 0.0008
Entamoeba histolytica P-glycoprotein 5, putative 0.0013 0.0017 0.0016
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0013 0.0019 0.0019
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Plasmodium falciparum importin beta, putative 0.0061 0.0371 0.0599
Schistosoma mansoni malate dehydrogenase 0.0324 0.2315 0.2315
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0026
Schistosoma mansoni hypothetical protein 0.0431 0.3108 0.3108
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0064 0.0185
Trypanosoma cruzi malate dehydrogenase, putative 0.0324 0.2315 1
Plasmodium vivax lactate/malate dehydrogenase, putative 0.0324 0.2315 0.3802
Echinococcus multilocularis lactate dehydrogenase protein 0.0833 0.6076 0.6076
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.0833 0.6076 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0017 0.0017
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0324 0.2315 0.2315
Trypanosoma cruzi cytochrome P450 reductase, putative 0.003 0.0144 0.0592
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0285 0.1159
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0216 0.0905
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Echinococcus multilocularis muscleblind protein 1 0.0451 0.3257 0.3257
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0323 0.2306 0.8959
Trichomonas vaginalis abcb9, putative 0.0013 0.0017 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0062 0.038 0.038
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0023 0.0091 0.029
Loa Loa (eye worm) hypothetical protein 0.0236 0.1665 0.274
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.3108 0.3108
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Brugia malayi RNA binding protein 0.0062 0.038 0.0625
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0141 0.0968 0.3721
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0069 0.0114
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0013 0.0019 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.008
Echinococcus granulosus FTZ F1 alpha 0.002 0.0069 0.0069
Mycobacterium tuberculosis Probable oxidoreductase 0.0359 0.2572 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0049 0.0282 0.1193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0216 0.0216
Brugia malayi multidrug resistance protein 3 0.0013 0.0017 0.0027
Onchocerca volvulus 0.0236 0.1665 1
Schistosoma mansoni cytochrome P450 reductase 0.003 0.0144 0.0144
Entamoeba histolytica malate dehydrogenase, putative 0.0324 0.2315 0.3802
Entamoeba histolytica P-glycoprotein-2, putative 0.0013 0.0017 0.0016
Schistosoma mansoni microtubule-associated protein tau 0.1363 1 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0069 0.0114
Onchocerca volvulus 0.004 0.0216 0.1209
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.0019 0.005
Loa Loa (eye worm) hypothetical protein 0.0055 0.0326 0.0536
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0017 0.0041
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0017 0.0041
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0252 0.0404
Echinococcus granulosus Mastin 0.0236 0.1665 0.1665
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0252 0.1063
Echinococcus multilocularis lactate dehydrogenase a 0.0833 0.6076 0.6076
Giardia lamblia Hypothetical protein 0.0027 0.0119 0.0435
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0064 0.0075
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0071 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0027
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0392 0.0644
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Echinococcus multilocularis geminin 0.0187 0.1303 0.1303
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0023 0.0091 0.0314
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0013 0.0019 0.0031
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0137 0.0936 0.154
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0069 0.0114
Plasmodium vivax multidrug resistance protein 1, putative 0.0013 0.0017 0.0016
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0254 0.1797 0.6966
Trypanosoma cruzi cytochrome P450 reductase, putative 0.003 0.0144 0.0592
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0069 0.0319
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0013 0.0019 0.0031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.1203
Toxoplasma gondii flavodoxin domain-containing protein 0.0015 0.0032 0.0041
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0019 0.0019
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0648 0.4708 0.7749
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0069 0.0114
Loa Loa (eye worm) multidrug resistance protein 3 0.0013 0.0017 0.0027
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.0395 0.0395
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0013 0.0019 0.0019
Trichomonas vaginalis hypothetical protein 0.0011 0.0007 0.0001
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0071 0.0451 0.1922
Schistosoma mansoni malate dehydrogenase 0.0833 0.6076 0.6076
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0064 0.0246
Loa Loa (eye worm) thioredoxin reductase 0.0141 0.0968 0.1592
Schistosoma mansoni tar DNA-binding protein 0.0062 0.038 0.038
Schistosoma mansoni importin-beta 2 0.0011 0.0007 0.0007
Schistosoma mansoni thyroid hormone receptor 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0069 0.0069
Leishmania major hypothetical protein, conserved 0.0013 0.0019 0.0019
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0069 0.0069
Chlamydia trachomatis thioredoxin reductase 0.0013 0.0019 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0069 0.0069
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0069 0.0114
Schistosoma mansoni disulfide oxidoreductase 0.0013 0.0019 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0069 0.0114
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0285 0.1203
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0013 0.0019 0.0019
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0049 0.0282 0.1193
Entamoeba histolytica P-glycoprotein-2 0.0013 0.0017 0.0016
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0013 0.0017 0.0041
Onchocerca volvulus 0.004 0.0216 0.1209
Echinococcus granulosus GPCR family 2 0.0063 0.0392 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0386 0.1641
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.004 0.0216 0.0355
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0091 0.0362
Toxoplasma gondii hypothetical protein 0.0023 0.0091 0.0138
Schistosoma mansoni hypothetical protein 0.0137 0.0936 0.0936
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0048 0.0048
Brugia malayi ecdysteroid receptor 0.002 0.0069 0.0114
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0359 0.2572 1
Entamoeba histolytica hypothetical protein 0.0049 0.0286 0.046
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0216 0.078
Echinococcus multilocularis L lactate dehydrogenase 0.0509 0.3684 0.3684
Mycobacterium tuberculosis Probable reductase 0.0323 0.2306 0.8959
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0324 0.2315 0.2315
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0013 0.0019 0.0019
Plasmodium falciparum lactate dehydrogenase, putative 0.0324 0.2315 0.3802
Trichomonas vaginalis glutaminase, putative 0.0272 0.1933 0.8348
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0069 0.0069
Brugia malayi kap beta 3 protein 0.0011 0.0007 0.0012
Loa Loa (eye worm) FAD binding domain-containing protein 0.0018 0.0059 0.0097
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0018 0.0059 0.0059
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0013 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.004 0.0216 0.0355
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.0324 0.2315 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0048 0.0068
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0216 0.078
Entamoeba histolytica Ran family GTPase 0.0045 0.0252 0.0404
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0013 0.0019 0.0008
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0027 0.0119 0.0483
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0216 0.0905
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0048 0.0179
Schistosoma mansoni malate dehydrogenase 0.0324 0.2315 0.2315
Echinococcus multilocularis microtubule associated protein 2 0.1363 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0019 0.005
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0324 0.2315 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0252 0.0404
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0071 0.0451 0.1922
Schistosoma mansoni hypothetical protein 0.0063 0.0392 0.0392
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0019 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0069 0.0114
Loa Loa (eye worm) TAR-binding protein 0.0062 0.038 0.0625
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0216 0.078
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus granulosus L lactate dehydrogenase B chain 0.0833 0.6076 0.6076
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.0457
Loa Loa (eye worm) hypothetical protein 0.0236 0.1665 0.274
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus granulosus glutamate synthase 0.0013 0.0019 0.0019
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0011 0.0007 0.0001
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0017 0.0017
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.0019 0.005
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0216 0.0905
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0017 0.0041
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.0019 0.005
Schistosoma mansoni cpg binding protein 0.0032 0.0159 0.0159
Toxoplasma gondii lactate dehydrogenase LDH1 0.0833 0.6076 1
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0069 0.0319
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0359 0.2572 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0071 0.0451 0.1922
Plasmodium falciparum L-lactate dehydrogenase 0.0833 0.6076 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0323 0.2306 0.8959
Echinococcus multilocularis transportin 1 0.0011 0.0007 0.0007
Leishmania major cytochrome P450 reductase, putative 0.0027 0.0119 0.0184
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0395 0.0395
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0062 0.038 0.038
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0048 0.0048
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0285 0.1203
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0252 0.0252
Leishmania major importin beta-1 subunit, putative 0.0049 0.0286 0.046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Loa Loa (eye worm) malate dehydrogenase 0.0324 0.2315 0.3809
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0069 0.0069
Plasmodium vivax malate dehydrogenase, putative 0.0833 0.6076 1
Echinococcus multilocularis glutamate synthase 0.0013 0.0019 0.0019
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0069 0.0069
Plasmodium falciparum glutathione reductase 0.0141 0.0968 0.1582
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0069 0.0069
Loa Loa (eye worm) programmed cell death 8 0.0013 0.0019 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Leishmania major p-glycoprotein 0.0013 0.0017 0.0016
Brugia malayi glutamate synthase 0.0013 0.0019 0.0031
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0017 0.0017
Mycobacterium ulcerans hypothetical protein 0.004 0.0216 0.0859
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0069 0.0114
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0048 0.0048
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0063 0.0392 0.0392
Toxoplasma gondii hypothetical protein 0.0063 0.0386 0.0624
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0048 0.008
Echinococcus multilocularis snurportin 1 0.0648 0.4708 0.4708
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.0019 0.005
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.0324 0.2315 0.3809
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.018 0.018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0069 0.0069
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.003 0.0144 0.0144
Toxoplasma gondii selenide, water dikinase 0.0013 0.0019 0.0019
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0019 0.005
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0048 0.0048
Trichomonas vaginalis ran, putative 0.0045 0.0252 0.1063
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.0019 0.0019
Chlamydia trachomatis malate dehydrogenase 0.0324 0.2315 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.0019 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0019 0.005
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0648 0.4708 0.4708
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0408 0.0408
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0252 0.0415
Echinococcus multilocularis enteropeptidase 0.0236 0.1665 0.1665
Trypanosoma brucei trypanothione reductase 0.0141 0.0968 0.4162
Mycobacterium ulcerans malate dehydrogenase 0.0324 0.2315 1
Loa Loa (eye worm) FAD binding domain-containing protein 0.003 0.0144 0.0237
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0216 0.0216
Loa Loa (eye worm) kap beta 3 protein 0.0011 0.0007 0.0012
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0071 0.0451 0.1922
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0019 0.005
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0048 0.0048
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Plasmodium falciparum thioredoxin reductase 0.0049 0.0285 0.0457
Plasmodium falciparum GAF domain-related protein, putative 0.0023 0.0091 0.0138
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0155 0.1069 0.4115
Giardia lamblia Nitric oxide synthase, inducible 0.0027 0.0119 0.0435
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0032 0.0156 0.0256
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Plasmodium vivax lactate dehydrogenase 0.0833 0.6076 1
Echinococcus multilocularis lactate dehydrogenase a 0.0833 0.6076 0.6076
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Loa Loa (eye worm) glutaminase 2 0.0272 0.1933 0.3182
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.0019 0.0019
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0048 0.0179
Mycobacterium leprae Probable lipase LipE 0.004 0.0216 0.0773
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0017 0.0017
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0048 0.0048
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.1203
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0285 0.1159
Treponema pallidum fructose-bisphosphate aldolase 0.0318 0.227 1
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0324 0.2315 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0216 0.0355
Plasmodium falciparum multidrug resistance protein 1 0.0013 0.0017 0.0016
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0023 0.0091 0.029
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0017 0.0041
Entamoeba histolytica hypothetical protein 0.0035 0.018 0.0285
Loa Loa (eye worm) hypothetical protein 0.0451 0.3257 0.536
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0013 0.0019 0.0019
Plasmodium falciparum malate dehydrogenase 0.0833 0.6076 1
Brugia malayi Trypsin family protein 0.0236 0.1665 0.274
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0064 0.0251
Schistosoma mansoni hypothetical protein 0.0013 0.0019 0.0019
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0392 0.0644
Echinococcus multilocularis L lactate dehydrogenase B chain 0.0833 0.6076 0.6076
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0323 0.2306 0.8959
Echinococcus granulosus cytosolic malate dehydrogenase 0.0324 0.2315 0.2315
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0032 0.0156 0.0256
Echinococcus granulosus tar DNA binding protein 0.0062 0.038 0.038
Echinococcus multilocularis malate dehydrogenase 0.0324 0.2315 0.2315
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0286 0.1209
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0091 0.0138
Leishmania major mitochondrial malate dehydrogenase 0.0324 0.2315 0.3802
Mycobacterium tuberculosis Conserved protein 0.004 0.0216 0.078
Treponema pallidum thioredoxin reductase (trxB) 0.0013 0.0019 0.0051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0064 0.0246
Echinococcus granulosus importin subunit beta 1 0.0061 0.0371 0.0371
Entamoeba histolytica hypothetical protein 0.0035 0.018 0.0285
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0069 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0285 0.1203
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0285 0.0457
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.008
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0408 0.0671
Echinococcus granulosus lactate dehydrogenase a 0.0833 0.6076 0.6076
Brugia malayi hypothetical protein 0.0035 0.018 0.0297
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Schistosoma mansoni glutamate synthase 0.0013 0.0019 0.0019
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0069 0.0069
Echinococcus granulosus NADPH cytochrome P450 reductase 0.003 0.0144 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0451 0.1922
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0216 0.0859
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0017 0.0041
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0019 0.0031
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0032 0.0156 0.0156
Schistosoma mansoni ap endonuclease 0.0019 0.0064 0.0064
Schistosoma mansoni ran 0.0045 0.0252 0.0252
Entamoeba histolytica P-glyco protein 6, putative 0.0013 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0114
Schistosoma mansoni L-lactate dehydrogenase 0.0833 0.6076 0.6076
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0013 0.0019 0.0019
Echinococcus granulosus enteropeptidase 0.0236 0.1665 0.1665
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0069 0.0069
Echinococcus granulosus importin 5 0.0011 0.0007 0.0007
Schistosoma mansoni sulfide quinone reductase 0.0013 0.0019 0.0019
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0017 0.0041
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0019 0.005
Brugia malayi nuclear receptor NHR-88 0.002 0.0069 0.0114
Leishmania major malate dehydrogenase 0.0324 0.2315 0.3802
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Schistosoma mansoni hypothetical protein 0.0236 0.1665 0.1665
Brugia malayi steroid hormone receptor 0.002 0.0069 0.0114
Echinococcus granulosus transmembrane protease serine 3 0.0236 0.1665 0.1665
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0069 0.0069
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0032 0.0156 0.0644
Schistosoma mansoni multidrug resistance protein 0.0013 0.0017 0.0017
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0216 0.078
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0252 0.0415
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0236 0.1665 0.1665
Brugia malayi beta-lactamase family protein 0.004 0.0216 0.0355
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0069 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0069 0.0114
Schistosoma mansoni hypothetical protein 0.0236 0.1665 0.1665
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0069 0.0069
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0285 0.0457
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0371 0.0371
Schistosoma mansoni L-lactate dehydrogenase 0.0324 0.2315 0.2315
Entamoeba histolytica malate dehydrogenase, putative 0.0833 0.6076 1
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0324 0.2315 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0392 0.0392
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0285 0.1203
Echinococcus granulosus lactate dehydrogenase protein 0.0833 0.6076 0.6076
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0017 0.0041
Schistosoma mansoni malate dehydrogenase 0.0324 0.2315 0.2315
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0286 0.1209
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0371 0.1576
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0013 0.0019 0.0019
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0071 0.0451 0.1922
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0236 0.1665 0.274
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Giardia lamblia Malate dehydrogenase 0.0324 0.2315 1
Plasmodium falciparum ferrodoxin reductase-like protein 0.0013 0.0019 0.0019
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0013 0.0019 0.005
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Echinococcus granulosus tumor protein p63 0.0373 0.2676 0.2676
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0285 0.1203
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0252 0.1063
Trichomonas vaginalis malate dehydrogenase, putative 0.0158 0.1088 0.4684
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0017 0.0017
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0071 0.0451 0.1922
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0071 0.0451 0.0451
Loa Loa (eye worm) trypsin family protein 0.0236 0.1665 0.274
Brugia malayi Importin beta-1 subunit 0.0061 0.0371 0.061
Schistosoma mansoni cercarial elastase (S01 family) 0.0236 0.1665 0.1665
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0069 0.0114
Echinococcus multilocularis transmembrane protease serine 3 0.0236 0.1665 0.1665
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.0019 0.005
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0017 0.0041
Leishmania major hypothetical protein, conserved 0.0013 0.0019 0.0019
Trichomonas vaginalis malate dehydrogenase, putative 0.0324 0.2315 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0236 0.1665 0.1665
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0048 0.0179
Brugia malayi jmjC domain containing protein 0.0064 0.0395 0.065
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0323 0.2306 0.8958
Toxoplasma gondii exonuclease III APE 0.0019 0.0064 0.0093
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0069 0.0069
Onchocerca volvulus 0.0055 0.0326 0.1874
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0017 0.0041
Schistosoma mansoni sulfide quinone reductase 0.0013 0.0019 0.0019
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.008
Brugia malayi glutaminase DH11.1 0.0272 0.1933 0.3182
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0017 0.0041
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0013 0.0019 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.227 0.9808
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0285 0.1159

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 80 uM Concentration of compound required to inhibit binding of [125I]-J-BH-CCK-8 radioligand to CCKA in mouse pancreatic membranes ChEMBL. No reference
IC50 (binding) > 80 uM Concentration of compound required to inhibit binding of [125I]-J-BH-CCK-8 radioligand to CCKB in mouse fore brain membranes ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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