Detailed information for compound 2069970

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 344.491 | Formula: C21H32N2O2
  • H donors: 1 H acceptors: 1 LogP: 2.85 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCN1CCC(CC1)CNC(=O)C1(CC1)c1cc(C)cc(c1)C
  • InChi: 1S/C21H32N2O2/c1-16-12-17(2)14-19(13-16)21(6-7-21)20(24)22-15-18-4-8-23(9-5-18)10-11-25-3/h12-14,18H,4-11,15H2,1-3H3,(H,22,24)
  • InChiKey: RYVZZFIVBNZKST-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.007 0.0283 0.0279
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0153 0.0653 0.7704
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0051 0.0199 0.0233
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0017 0.0173
Echinococcus granulosus voltage gated hydrogen channel 1 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0107
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0056 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trypanosoma cruzi target of rapamycin kinase 3 0.0012 0.0025 0.0042
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Schistosoma mansoni DNA polymerase eta 0.0023 0.0077 0.0087
Brugia malayi phosphoinositide-dependent protein kinase I 0.0016 0.0045 0.0041
Brugia malayi Protein kinase c protein 2 0.0026 0.0089 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0072
Trypanosoma brucei unspecified product 0.0023 0.0077 0.0164
Echinococcus multilocularis two pore calcium channel protein 2 0.0019 0.0056 0.0132
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Echinococcus granulosus hypothetical protein 0.0019 0.0056 0.0132
Schistosoma mansoni serine/threonine-protein kinase 0.0008 0.0011 0.0008
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0037 0.0136 0.0415
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.0031 0.0068
Echinococcus multilocularis microtubule associated protein 2 0.0361 0.1578 0.3981
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.1057 0.4673 1
Trypanosoma brucei trypanothione reductase 0.0033 0.0118 0.0253
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0118 0.0242
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0016 0.0045 0.0103
Echinococcus granulosus potassium large conductance calcium activated 0.0019 0.0056 0.0132
Brugia malayi phospholipase C homolog 0.0016 0.0046 0.0042
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0077 0.0106
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0025 0.0082 0.6828
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0019 0.0056 0.0132
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0056 0.0132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Loa Loa (eye worm) MIR domain-containing protein 0.0196 0.0846 0.122
Entamoeba histolytica PH domain containing protein kinase, putative 0.0008 0.0011 0.0081
Schistosoma mansoni hypothetical protein 0.0019 0.0056 0.0062
Echinococcus multilocularis cytohesin 1 0.0091 0.0377 0.0944
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0005 0.0011
Schistosoma mansoni hypothetical protein 0.001 0.0019 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0113
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1898 0.8412 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0038 0.0426
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0015 0.0038 0.007
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0039 0.0146 0.0301
Toxoplasma gondii NADPH-glutathione reductase 0.0011 0.0023 0.0811
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis stromal cell derived factor 2 0.0196 0.0846 0.213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Echinococcus granulosus sodium leak channel non selective protein 0.0019 0.0056 0.0132
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.1057 0.4673 1
Schistosoma mansoni atypical protein kinase C 0.001 0.0018 0.0017
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0019 0.0056 0.0132
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0056 0.0132
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0019 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0023 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Brugia malayi protein kinase C II. 0.0012 0.0027 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0045 0.0059
Echinococcus multilocularis sodium channel protein 0.0019 0.0056 0.0132
Echinococcus multilocularis two pore calcium channel protein 1 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0056 0.2271
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0045 0.0505
Trypanosoma cruzi CYC2-like cyclin 4, putative 0.0008 0.0007 0.0004
Entamoeba histolytica protein kinase, putative 0.0016 0.0045 0.0484
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0056 0.0132
Echinococcus granulosus shaker cognate 0.0019 0.0056 0.0132
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.001 0.0019 0.0022
Brugia malayi hypothetical protein 0.001 0.0019 0.0015
Loa Loa (eye worm) voltage-dependent calcium channel 0.0019 0.0056 0.0076
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0008 0.0007 0.008
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.001 0.0019 0.0015
Schistosoma mansoni loxhd1 0.001 0.0019 0.0018
Brugia malayi Doublecortin family protein 0.001 0.0019 0.0015
Schistosoma mansoni phospholipase C beta 0.001 0.0019 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Loa Loa (eye worm) AGC/AKT protein kinase 0.0015 0.004 0.0052
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.007 0.0283 0.0404
Schistosoma mansoni DNA polymerase IV / kappa 0.0007 0.0005 0.0002
Onchocerca volvulus 0.001 0.0019 0.0182
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0007 0.0004 0.0000046119
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus granulosus serine:threonine protein kinase N2 0.0007 0.0004 0.0000080509
Trypanosoma brucei unspecified product 0.0016 0.0045 0.0095
Schistosoma mansoni transient receptor potential channel 0.0019 0.0056 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0012 0.0117
Schistosoma mansoni hypothetical protein 0.019 0.0817 0.0967
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0013 0.0031 0.008
Trypanosoma cruzi trypanothione reductase, putative 0.0011 0.0023 0.0039
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0007 0.0004 0.0000046119
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0056 0.0132
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0033 0.0118 0.0288
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0025 0.0082 0.0079
Plasmodium falciparum glutathione reductase 0.0033 0.0118 1
Echinococcus granulosus ryanodine receptor 44f 0.0696 0.3066 0.7742
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0019 0.0056 0.0052
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0056 0.0132
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0056 0.0132
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.001 0.0019 0.0204
Entamoeba histolytica protein kinase, putative 0.0015 0.004 0.0424
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0015 0.0038 0.0405
Loa Loa (eye worm) hypothetical protein 0.156 0.6907 1
Echinococcus granulosus cytohesin 1 0.0091 0.0377 0.0944
Schistosoma mansoni voltage-gated ion channel 0.0019 0.0056 0.0062
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.0031 0.0055
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0605
Echinococcus granulosus NDR protein kinase 0.0007 0.0004 0.0000080509
Brugia malayi phospholipase C homolog 0.0043 0.0165 0.0161
Echinococcus multilocularis shaker cognate 0.0019 0.0056 0.0132
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0056 0.062
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0005 0.0011
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0029 0.0101 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0012 0.0117
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0077 0.0226
Loa Loa (eye worm) hypothetical protein 0.0094 0.0391 0.0561
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0056 0.0132
Echinococcus granulosus cyclin dependent kinase 1 0.0013 0.0031 0.0068
Echinococcus multilocularis ryanodine receptor 44f 0.0696 0.3066 0.7742
Plasmodium falciparum glutathione reductase 0.0011 0.0023 0.1606
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0011 0.0023 0.0811
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Plasmodium vivax phospholipase C-like, putative 0.0025 0.0082 0.6828
Echinococcus granulosus microtubule associated protein 2 0.0361 0.1578 0.3981
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0015 0.0038 0.0081
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0023
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0007 0.0004 0.0000080509
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.0044
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0196 0.0846 0.1002
Loa Loa (eye worm) Plcb4 protein 0.0057 0.0228 0.0325
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0005 0.0011
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Echinococcus multilocularis protein kinase c iota type 0.001 0.0018 0.0035
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0011 0.0023 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Schistosoma mansoni microtubule-associated protein tau 0.0361 0.1578 0.1872
Plasmodium falciparum thioredoxin reductase 0.0033 0.0118 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0012 0.0025 0.0062
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0015 0.0038 0.0405
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0019 0.0056 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0045 0.0505
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0077 0.0087
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0005 0.0011
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Trypanosoma cruzi Protein kinase B 0.0008 0.0011 0.0012
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0013 0.0031 0.0068
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0023 0.005
Trypanosoma brucei cyclin 2 0.0008 0.0007 0.0015
Schistosoma mansoni hypothetical protein 0.019 0.0817 0.0967
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0019 0.0056 0.0109
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0091 0.0377 0.0444
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0019 0.0056 0.0062
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0077 0.0087
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0056 0.2271
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0337 0.0711
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0007 0.0004 0.0000080509
Echinococcus multilocularis cyclin dependent kinase 5 0.0013 0.0031 0.0068
Schistosoma mansoni serine/threonine kinase 0.0007 0.0004 0.0000037865
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0057
Giardia lamblia Kinase, CMGC CDK 0.0013 0.0031 0.0393
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Entamoeba histolytica protein kinase, putative 0.0015 0.004 0.0424
Schistosoma mansoni ryanodine receptor related 0.1254 0.5546 0.6591
Plasmodium falciparum cyclin, putative 0.0008 0.0007 0.0159
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0011 0.0023 0.1606
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1359 0.6015 0.7149
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.0031 0.0319
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0056 0.062
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0019 0.0038
Brugia malayi cell division control protein 2 homolog 0.0013 0.0031 0.0027
Plasmodium vivax cyclin, putative 0.0008 0.0007 0.0159
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0007 0.0004 0.0000046119
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0019 0.0056 0.0052
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Entamoeba histolytica MIR domain protein 0.0196 0.0846 1
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0025 0.0082 0.0244
Echinococcus granulosus cyclin dependent kinase 5 0.0013 0.0031 0.0068
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0059 0.0238 0.0591
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0056 0.0132
Onchocerca volvulus 0.0196 0.0846 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0008 0.001 0.0006
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0011 0.0023 0.0057
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0056 0.2271
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0075 0.0305 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0045 0.0095
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) variant SH3 domain-containing protein 0.003 0.0109 0.0152
Leishmania major hypothetical protein, conserved 0.0719 0.3168 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0077 0.1892
Trichomonas vaginalis mercuric reductase, putative 0.0011 0.0023 0.0254
Plasmodium falciparum LCCL domain-containing protein 0.001 0.0019 0.1213
Echinococcus granulosus Polycystic kidney disease protein 0.001 0.0019 0.0038
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0011 0.0023 0.005
Entamoeba histolytica protein kinase, putative 0.0011 0.0023 0.0224
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Onchocerca volvulus 0.0035 0.0127 0.1459
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0031 0.0341
Loa Loa (eye worm) hypothetical protein 0.1359 0.6015 0.8707
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.0031 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0045 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0072
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Trypanosoma brucei unspecified product 0.0016 0.0045 0.0095
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0019 0.0056 0.0132
Trypanosoma brucei glycosylphosphatidylinositol-specific phospholipase C 0.001 0.0019 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Giardia lamblia NADH oxidase lateral transfer candidate 0.0011 0.0023 0.028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0077 0.0164
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0077 0.0184
Loa Loa (eye worm) hypothetical protein 0.0082 0.0337 0.0483
Onchocerca volvulus 0.0072 0.0292 0.3416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0031 0.0032
Echinococcus multilocularis Polycystic kidney disease protein 0.001 0.0019 0.0038
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0056 0.0132
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0013 0.0031 0.1139
Echinococcus granulosus thioredoxin glutathione reductase 0.0033 0.0118 0.0289
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0056 0.0132
Echinococcus granulosus dna polymerase kappa 0.0023 0.0077 0.0184
Echinococcus multilocularis calcium activated potassium channel 0.0019 0.0058 0.0137
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0056 0.0076
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0056 0.0062
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0077 0.0073
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0153 0.0653 0.7704
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0118 0.0136
Brugia malayi glutathione reductase 0.0033 0.0118 0.0114
Brugia malayi MIR domain containing protein 0.0196 0.0846 0.0843
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0019 0.0056 0.016
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0043 0.0165 0.0191
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0039 0.0146 0.0312
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0056 0.0052
Schistosoma mansoni voltage-dependent calcium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis ryanodine receptor 44f 0.0897 0.3958 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0019 0.0056 0.0052
Toxoplasma gondii cyclin2 related protein 0.0008 0.0007 0.008
Echinococcus multilocularis serine threonine protein kinase 0.0029 0.0104 0.0253
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0007 0.0004 0.0000080509
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus multilocularis thioredoxin glutathione reductase 0.0033 0.0118 0.0289
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0077 0.2382
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0007 0.0004 0.0000080509
Schistosoma mansoni vesicular amine transporter 0.0019 0.0056 0.0062
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0077 0.0184
Loa Loa (eye worm) doublecortin family protein 0.001 0.0019 0.0022
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0056 0.0132
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0019 0.0056 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni lipoxygenase 0.001 0.0019 0.0018
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0077 0.0885
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0118 0.0136
Echinococcus multilocularis serine:threonine protein kinase N2 0.0007 0.0004 0.0000080509
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0019 0.0056 0.0062
Brugia malayi hypothetical protein 0.0019 0.0056 0.0052
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0019 0.0056 0.0132
Echinococcus granulosus TRP transient receptor potential channel 0.0019 0.0056 0.0132
Echinococcus granulosus sodium channel protein 0.0019 0.0056 0.0132
Trypanosoma brucei cdc2-related kinase 1 0.0013 0.0031 0.0066
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0056 0.0132
Echinococcus granulosus stromal cell derived factor 2 0.0196 0.0846 0.213
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0011 0.0023 0.1606
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0056 0.0052
Echinococcus multilocularis dna polymerase eta 0.0023 0.0077 0.0184
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0023 0.005
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0057 0.0228 0.0224
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0011 0.0023 0.1606
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0011 0.0023 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0015 0.0038 0.007
Brugia malayi hypothetical protein 0.001 0.0019 0.0015
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0045 0.0505
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0056 0.0062
Loa Loa (eye worm) ryanodine receptor 0.0339 0.1478 0.2135
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0011 0.0023 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0027 0.0028
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0038 0.0034
Loa Loa (eye worm) ryanodine receptor 0.0019 0.0056 0.0076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0019 0.0056 0.0062
Schistosoma mansoni serine/threonine-protein kinase 0.0008 0.0011 0.0008
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0016 0.0045 0.0103
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Echinococcus multilocularis RUN 0.001 0.0019 0.0038
Schistosoma mansoni transient receptor potential channel 0.0019 0.0056 0.0062
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0023 0.5
Plasmodium vivax protein kinase Crk2 0.0013 0.0031 0.2253
Leishmania major trypanothione reductase 0.0033 0.0118 0.0357
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Brugia malayi p70 ribosomal S6 kinase beta 0.0011 0.0023 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0056 0.2271
Loa Loa (eye worm) AGC/PKN protein kinase 0.0007 0.0004 0.0000046119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0056 0.0132
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0077 0.0865
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0029 0.0101 0.0247
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0015 0.0038 0.0103
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0007 0.0004 0.0000080509
Loa Loa (eye worm) AGC/NDR protein kinase 0.0007 0.0004 0.0000046119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0015 0.0157
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0056 0.0132
Loa Loa (eye worm) calcium channel 0.0019 0.0056 0.0076
Echinococcus granulosus RNA directed DNA polymerase 0.002 0.0064 0.0152
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0008 0.0011 0.0012
Loa Loa (eye worm) cytohesin 3 0.0091 0.0377 0.0541
Echinococcus granulosus dna polymerase eta 0.0023 0.0077 0.0184
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Schistosoma mansoni polycystin 1-related 0.001 0.0019 0.0018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Giardia lamblia DINP protein human, muc B family 0.0023 0.0077 0.1103
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0056 0.0132
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0033 0.0118 0.3366
Schistosoma mansoni rab6-interacting 0.001 0.0019 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0019 0.0056 0.0052
Echinococcus multilocularis cyclin dependent kinase 0.0013 0.0031 0.0068
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0056 0.0132
Echinococcus granulosus protein kinase C gamma type 0.0029 0.0104 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0011 0.0023 0.0605
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0056 0.0076
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0075 0.0305 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0153 0.0653 1
Loa Loa (eye worm) hypothetical protein 0.1537 0.6805 0.9851
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0019 0.0056 0.0132
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0019 0.0056 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0023
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Brugia malayi Cytohesin 3 0.0091 0.0377 0.0374
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Treponema pallidum fructose-bisphosphate aldolase 0.0153 0.0653 1
Brugia malayi voltage-dependent calcium channel 0.0019 0.0056 0.0052
Loa Loa (eye worm) thioredoxin reductase 0.0033 0.0118 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0019 0.0056 0.0132
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0113
Echinococcus granulosus RUN 0.001 0.0019 0.0038
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0011 0.0023 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0011 0.0023 0.005
Echinococcus granulosus protein kinase c iota type 0.001 0.0018 0.0035
Brugia malayi Thioredoxin reductase 0.0033 0.0118 0.0114
Giardia lamblia Kinase, CMGC CDK 0.0013 0.0031 0.0393
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus granulosus protein kinase c epsilon type 0.0012 0.0027 0.0059
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0012 0.0025 0.0053
Brugia malayi Protein kinase domain containing protein 0.0015 0.004 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0028 0.0314
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Plasmodium vivax glutathione reductase, putative 0.0033 0.0118 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0045 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0031 0.0341
Echinococcus granulosus ryanodine receptor 44f 0.0897 0.3958 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0238 0.0339
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0021 0.0222
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Brugia malayi polk-prov protein 0.0007 0.0005 0.0001
Echinococcus multilocularis serine:threonine protein kinase 38 0.0007 0.0004 0.0000080509
Loa Loa (eye worm) voltage-gated calcium channel 0.0019 0.0056 0.0076
Echinococcus multilocularis transient receptor potential gamma protein 0.0019 0.0056 0.0132
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0019 0.0038
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0015 0.0038 0.0041
Onchocerca volvulus 0.001 0.0019 0.018
Plasmodium vivax multidomain scavenger receptor, putative 0.001 0.0019 0.1213
Loa Loa (eye worm) glutathione reductase 0.0033 0.0118 0.0166
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0019 0.0056 0.0132
Onchocerca volvulus 0.001 0.0019 0.018
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0056 0.0062
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.1254 0.5546 0.5545
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0019 0.0056 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0005 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0019 0.0056 0.0132
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0056 0.064
Schistosoma mansoni phospholipase C beta 0.0057 0.0228 0.0267
Onchocerca volvulus 0.0019 0.0056 0.062
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0023 0.5
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Leishmania major CYC2-like cyclin, putative 0.0008 0.0007 0.0006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0075 0.0305 1
Echinococcus granulosus two pore calcium channel protein 2 0.0019 0.0056 0.0132
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0019 0.0038
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.0031 0.0068
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0077 0.0153
Schistosoma mansoni lipoxygenase 0.0029 0.0101 0.0116
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0077 0.0164
Brugia malayi Hr1 repeat family protein 0.0007 0.0004 0.0000031851
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0023 0.0039
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0019 0.0056 0.0052
Schistosoma mansoni two-pore calcium channel 0.0019 0.0056 0.0062
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0337 0.0711
Loa Loa (eye worm) hypothetical protein 0.0082 0.0337 0.0483
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Brugia malayi Protein kinase domain containing protein 0.0007 0.0004 0.0000031851
Leishmania major DNA polymerase kappa, putative 0.0023 0.0077 0.0226
Echinococcus granulosus cyclin dependent kinase 0.0013 0.0031 0.0068
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0059 0.0238 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0031 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0077 0.0885
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0019 0.0056 0.0052
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0019 0.0056 0.0052
Trichomonas vaginalis mannosyltransferase 1, putative 0.0196 0.0846 1
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0019 0.0056 0.0052
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0057
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0077 0.0164
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0178
Loa Loa (eye worm) hypothetical protein 0.0007 0.0004 0.0000046119
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Trypanosoma brucei cdc2-related kinase 3 0.0013 0.0031 0.0066
Brugia malayi olfactory channel protein osm-9 0.0019 0.0056 0.0052
Echinococcus granulosus two pore calcium channel protein 1 0.0019 0.0056 0.0132
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0056 0.0052
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0058 0.0229 1
Brugia malayi Transient-receptor-potential like protein 0.0019 0.0056 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0038 0.0049
Echinococcus multilocularis protein kinase c epsilon type 0.0012 0.0027 0.0059
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0077 0.1892
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0019 0.0038
Onchocerca volvulus 0.0102 0.0429 0.5042
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0012 0.0027 0.0034
Schistosoma mansoni voltage-gated cation channel 0.0019 0.0056 0.0062
Leishmania major inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0337 0.105
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0019 0.0056 0.0052
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0013 0.0031 0.008
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0077 0.0073
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0012 0.0117
Brugia malayi Protein kinase domain containing protein 0.0016 0.0045 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Loa Loa (eye worm) ion channel NompC 0.0019 0.0056 0.0076
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Plasmodium falciparum protein kinase 5 0.0013 0.0031 0.2253
Schistosoma mansoni rab6-interacting 0.001 0.0019 0.0018
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0015 0.0038 0.0103
Loa Loa (eye worm) hypothetical protein 0.0897 0.3958 0.5728
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0077 0.0164
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Loa Loa (eye worm) hypothetical protein 0.0013 0.0029 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Toxoplasma gondii hypothetical protein 0.0019 0.0056 0.2271
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0022
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Echinococcus multilocularis potassium large conductance calcium activated 0.0019 0.0056 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0019 0.0056 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0114
Brugia malayi Protein kinase domain containing protein 0.0007 0.0004 0.0000031851
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Plasmodium falciparum thioredoxin reductase 0.0011 0.0023 0.1606
Echinococcus multilocularis rac serine:threonine kinase 0.0008 0.0011 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0005 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Echinococcus granulosus calcium activated potassium channel 0.0019 0.0058 0.0137
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Trypanosoma brucei chrX additional, unordered contigs 0.0007 0.0005 0.0011
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0339 0.1478 0.1753
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0056 0.0132
Entamoeba histolytica PH domain containing protein kinase, putative 0.0008 0.0011 0.0081
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0019 0.0056 0.0076
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.0031 0.0319
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Leishmania major DNA polymerase eta, putative 0.0023 0.0077 0.0226
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0015 0.0038 0.0086
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.0056 0.0062
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Trypanosoma cruzi CYC2-like cyclin 6, putative 0.0008 0.0007 0.0004
Echinococcus granulosus serine/threonine protein kinase 0.0008 0.0011 0.0017
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0008 0.001 0.0006
Echinococcus granulosus geminin 0.019 0.0817 0.2056
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.0031 0.0055
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Echinococcus multilocularis RNA directed DNA polymerase 0.002 0.0064 0.0152
Toxoplasma gondii target of rapamycin (TOR), putative 0.0011 0.0021 0.0719
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0019 0.0056 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0013 0.0031 0.0039
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.001 0.0019 0.0204
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0056 0.064
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0007 0.0004 0.0000080509
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0007 0.0004 0.0008
Echinococcus multilocularis geminin 0.019 0.0817 0.2056
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0056 0.0076
Plasmodium vivax thioredoxin reductase, putative 0.0033 0.0118 1
Schistosoma mansoni transient receptor potential channel 4 0.0019 0.0056 0.0062
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0106
Trypanosoma brucei rac serine-threonine kinase, putative 0.0015 0.004 0.0085
Brugia malayi Protein kinase domain containing protein 0.0013 0.0031 0.0027
Echinococcus multilocularis serine:threonine protein kinase N2 0.0007 0.0004 0.0000080509
Echinococcus granulosus Protein kinase C brain isozyme 0.0033 0.0118 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0038 0.0426
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0056 0.2271
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0045 0.0059
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Brugia malayi ion channel NompC 0.0019 0.0056 0.0052
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0086 0.0354 0.0758
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Schistosoma mansoni transient receptor potential channel 0.0019 0.0056 0.0062
Giardia lamblia GTOR 0.0015 0.0038 0.0505
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0015 0.0038 0.0086
Leishmania major hypothetical protein, unknown function 0.0019 0.0056 0.016
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0019 0.0056 0.0132
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Toxoplasma gondii AGC kinase 0.0011 0.0023 0.0781
Toxoplasma gondii thioredoxin reductase 0.0033 0.0118 0.5054
Echinococcus multilocularis sodium leak channel non selective protein 0.0019 0.0056 0.0132
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0077 0.2382
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0023 0.0075 0.0103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Trypanosoma brucei CYC2-like cyclin, putative 0.0008 0.0007 0.0015
Brugia malayi Variant SH3 domain containing protein 0.003 0.0109 0.0105
Leishmania major phospholipase c-like protein 0.0039 0.0146 0.0445
Loa Loa (eye worm) hypothetical protein 0.0082 0.0337 0.0483
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0077 0.0184
Brugia malayi cation channel family protein 0.0019 0.0056 0.0052
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0011 0.0023 0.1606
Echinococcus granulosus transient receptor potential gamma protein 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.002 0.0064 0.0152
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.0031 0.0055
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0038 0.0426
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0011 0.0023 0.002
Toxoplasma gondii hypothetical protein 0.0019 0.0056 0.2271
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0031 0.0341
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0056 0.0132
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.0031 0.0055
Trypanosoma cruzi CYC2-like cyclin, putative 0.0008 0.0007 0.0004
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0015 0.0038 0.0081
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.006
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis transfer RNA-Gly 0.0019 0.0056 0.0132
Trichomonas vaginalis glutathione reductase, putative 0.0011 0.0023 0.0254

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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