Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | TK protein kinase | 0.0066 | 0.0235 | 0.0215 |
Onchocerca volvulus | 0.0044 | 0.0059 | 0.0497 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0099 | 0.0857 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.3151 | 0.3137 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0437 | 0.0437 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.004 | 0.0021 | 0.1006 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.007 | 0.0262 | 0.0262 |
Brugia malayi | Dihydrofolate reductase | 0.1286 | 1 | 1 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | basigin related | 0.0092 | 0.0437 | 0.0437 |
Echinococcus multilocularis | Immunoglobulin | 0.0387 | 0.2802 | 0.2802 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0049 | 0.0099 | 0.0078 |
Echinococcus multilocularis | tyrosine protein kinase otk | 0.0119 | 0.0654 | 0.0654 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.0099 | 0.0099 |
Echinococcus multilocularis | Immunoglobulin | 0.0092 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0437 | 0.0417 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Schistosoma mansoni | nephrin | 0.0119 | 0.0654 | 0.0654 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0063 | 0.021 | 0.021 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0099 | 0.0857 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0387 | 0.2802 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0437 | 0.0417 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0099 | 0.0857 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0521 | 0.3876 | 0.3876 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0092 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0523 | 0.389 | 0.3877 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Schistosoma mansoni | septate junction protein | 0.0092 | 0.0437 | 0.0437 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0043 | 0.0048 | 0.0048 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0119 | 0.0654 | 0.0654 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0119 | 0.0654 | 0.0654 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0043 | 0.0048 | 0.0027 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Brugia malayi | Peroxidasin | 0.0119 | 0.0654 | 0.0634 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0119 | 0.0661 | 0.0641 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0099 | 0.0857 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Giardia lamblia | Kinase, NEK | 0.0154 | 0.0941 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0049 | 0.0099 | 0.0099 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0119 | 0.0654 | 0.0654 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0437 | 0.0437 |
Echinococcus granulosus | Immunoglobulin | 0.0092 | 0.0437 | 0.0437 |
Chlamydia trachomatis | dihydrofolate reductase | 0.1286 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0437 | 0.0437 |
Echinococcus multilocularis | Immunoglobulin | 0.0092 | 0.0437 | 0.0437 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0066 | 0.0235 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.2802 | 0.2787 |
Echinococcus granulosus | pro neuregulin 2 membrane bound | 0.0092 | 0.0437 | 0.0437 |
Echinococcus granulosus | lachesin | 0.0119 | 0.0654 | 0.0654 |
Toxoplasma gondii | hypothetical protein | 0.0039 | 0.002 | 0.0054 |
Echinococcus granulosus | roundabout 2 | 0.0119 | 0.0654 | 0.0654 |
Schistosoma mansoni | tyrosine kinase | 0.004 | 0.0021 | 0.0021 |
Echinococcus multilocularis | neurotracting:lsamp:neurotrimin:obcam | 0.0119 | 0.0654 | 0.0654 |
Echinococcus multilocularis | Immunoglobulin | 0.0387 | 0.2802 | 0.2802 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0049 | 0.0099 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.3535 | 0.3521 |
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0119 | 0.0654 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0141 | 0.0121 |
Schistosoma mansoni | septate junction protein | 0.0092 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0437 | 0.0417 |
Toxoplasma gondii | hypothetical protein | 0.0039 | 0.002 | 0.0054 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0039 | 0.002 | 0.002 |
Schistosoma mansoni | tyrosine kinase | 0.0043 | 0.0048 | 0.0048 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0485 | 0.3589 | 0.3575 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0092 | 0.0437 | 0.0437 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.004 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | SRC-1 | 0.007 | 0.0262 | 0.0242 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0109 | 0.0576 | 0.0576 |
Brugia malayi | basement membrane proteoglycan precursor | 0.0092 | 0.0437 | 0.0417 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0119 | 0.0654 | 0.0634 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0119 | 0.0654 | 0.0654 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0514 | 0.3824 | 0.3811 |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0092 | 0.0437 | 0.0437 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.1286 | 1 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Schistosoma mansoni | dihydrofolate reductase | 0.1286 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.007 | 0.0262 | 0.0262 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.007 | 0.0262 | 0.0262 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | hemicentin 1 | 0.0119 | 0.0654 | 0.0654 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0119 | 0.0654 | 0.0654 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus granulosus | roundabout 2 | 0.0119 | 0.0654 | 0.0654 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0806 | 0.6156 | 0.6148 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0055 | 0.0141 | 0.0141 |
Echinococcus granulosus | tyrosine kinase | 0.004 | 0.0021 | 0.0021 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Echinococcus granulosus | 3'partial|cell adhesion molecule:down regulated by | 0.0092 | 0.0437 | 0.0437 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0.0141 | 0.1322 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus granulosus | roundabout 2 | 0.0505 | 0.3752 | 0.3752 |
Echinococcus granulosus | neuroglian | 0.0414 | 0.3018 | 0.3018 |
Trypanosoma brucei | polo-like protein kinase | 0.0049 | 0.0099 | 0.0271 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0055 | 0.0141 | 0.0388 |
Echinococcus granulosus | contactin | 0.0136 | 0.0792 | 0.0792 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0485 | 0.3589 | 0.3589 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0492 | 0.3641 | 1 |
Brugia malayi | Heparan sulfate | 0.0092 | 0.0437 | 0.0417 |
Loa Loa (eye worm) | immunoglobulin domain-containing protein | 0.0092 | 0.0437 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.007 | 0.0262 | 0.0262 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | lachesin | 0.0119 | 0.0654 | 0.0654 |
Schistosoma mansoni | basigin related | 0.0092 | 0.0437 | 0.0437 |
Echinococcus multilocularis | dihydrofolate reductase | 0.1286 | 1 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0387 | 0.2802 | 0.2787 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Schistosoma mansoni | nephrin | 0.0414 | 0.3018 | 0.3018 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0055 | 0.0141 | 0.0141 |
Schistosoma mansoni | cell adhesion molecule | 0.0119 | 0.0654 | 0.0654 |
Giardia lamblia | Kinase, NEK | 0.0154 | 0.0941 | 1 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0779 | 0.5939 | 0.5939 |
Schistosoma mansoni | tyrosine kinase | 0.0043 | 0.0048 | 0.0048 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0779 | 0.5939 | 0.5939 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0779 | 0.5939 | 0.5939 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0099 | 0.0857 |
Loa Loa (eye worm) | TK protein kinase | 0.0806 | 0.6156 | 0.6148 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0492 | 0.3641 | 1 |
Schistosoma mansoni | neuroglian | 0.0119 | 0.0654 | 0.0654 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.1286 | 1 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus granulosus | neuroglian | 0.0119 | 0.0654 | 0.0654 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0492 | 0.3641 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Echinococcus granulosus | Immunoglobulin | 0.0387 | 0.2802 | 0.2802 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | hemicentin 1 | 0.0136 | 0.0792 | 0.0792 |
Echinococcus granulosus | peroxidasin | 0.0119 | 0.0654 | 0.0654 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.004 | 0.0021 | 0.0021 |
Onchocerca volvulus | Netrin receptor homolog | 0.0044 | 0.0059 | 0.0497 |
Plasmodium falciparum | NIMA related kinase 1 | 0.0154 | 0.0941 | 0.2584 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.007 | 0.0262 | 0.0262 |
Echinococcus multilocularis | tyrosine kinase | 0.004 | 0.0021 | 0.0021 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | neuroglian | 0.0414 | 0.3018 | 0.3018 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0119 | 0.0654 | 0.0634 |
Schistosoma mansoni | netrin receptor unc5 | 0.0092 | 0.0437 | 0.0437 |
Brugia malayi | Immunoglobulin domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.2802 | 0.2787 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0066 | 0.0235 | 0.0235 |
Echinococcus granulosus | tyrosine kinase | 0.0066 | 0.0235 | 0.0235 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0779 | 0.5939 | 0.5939 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.004 | 0.0021 | 0.0021 |
Toxoplasma gondii | GAF domain-containing protein | 0.0039 | 0.002 | 0.0054 |
Echinococcus granulosus | c src tyrosine kinase | 0.0043 | 0.0048 | 0.0048 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0066 | 0.0235 | 0.0235 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0059 | 0.0059 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.007 | 0.0262 | 0.0262 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.007 | 0.0262 | 0.0262 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0071 | 0.0269 | 0.0269 |
Schistosoma mansoni | cell adhesion molecule | 0.0092 | 0.0437 | 0.0437 |
Brugia malayi | Immunoglobulin domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0063 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0119 | 0.0654 | 0.0634 |
Schistosoma mansoni | roundabout | 0.0119 | 0.0654 | 0.0654 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0485 | 0.3589 | 0.3589 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.004 | 0.0021 | 0.0021 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0043 | 0.0048 | 0.0048 |
Brugia malayi | protein-tyrosine kinase | 0.0066 | 0.0235 | 0.0215 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.007 | 0.0262 | 0.0262 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.004 | 0.0021 | 0.0021 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0043 | 0.0048 | 0.0048 |
Echinococcus granulosus | defective proboscis extension response | 0.0387 | 0.2802 | 0.2802 |
Plasmodium vivax | NIMA-related protein kinase (Pfnek-1), putative | 0.0154 | 0.0941 | 0.2544 |
Echinococcus granulosus | hemicentin 1 | 0.0136 | 0.0792 | 0.0792 |
Echinococcus granulosus | Immunoglobulin | 0.0092 | 0.0437 | 0.0437 |
Echinococcus multilocularis | Immunoglobulin subtype | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | tyrosine kinase | 0.007 | 0.0262 | 0.0262 |
Schistosoma mansoni | septate junction protein | 0.0119 | 0.0654 | 0.0654 |
Echinococcus granulosus | dihydrofolate reductase | 0.1286 | 1 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.2802 | 0.2787 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.0092 | 0.0437 | 0.0437 |
Echinococcus multilocularis | cell adhesion molecule:down regulated by | 0.0092 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.047 | 0.3467 | 0.3453 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0092 | 0.0437 | 0.0417 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0063 | 0.021 | 0.021 |
Echinococcus multilocularis | peroxidasin | 0.0119 | 0.0654 | 0.0654 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0063 | 0.021 | 0.0189 |
Echinococcus multilocularis | neuroglian | 0.0119 | 0.0654 | 0.0654 |
Echinococcus granulosus | Immunoglobulin subtype | 0.0092 | 0.0437 | 0.0437 |
Plasmodium falciparum | GAF domain-related protein, putative | 0.0039 | 0.002 | 0.0054 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.007 | 0.0262 | 0.0262 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0049 | 0.0099 | 0.0078 |
Schistosoma mansoni | nephrin related | 0.0092 | 0.0437 | 0.0437 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0055 | 0.0141 | 0.0388 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Trichomonas vaginalis | AGC family protein kinase | 0.0154 | 0.0941 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0063 | 0.0207 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Onchocerca volvulus | Putative titin | 0.0044 | 0.0059 | 0.0497 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0437 | 0.0417 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0492 | 0.3641 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0043 | 0.0048 | 0.0048 |
Schistosoma mansoni | vesicular amine transporter | 0.0387 | 0.2802 | 0.2802 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0387 | 0.2802 | 0.2802 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0387 | 0.2802 | 0.2787 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0055 | 0.0141 | 0.0388 |
Brugia malayi | SRC-1 | 0.007 | 0.0262 | 0.0242 |
Brugia malayi | Prion-like- | 0.0119 | 0.0654 | 0.0634 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0492 | 0.3641 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0779 | 0.5939 | 0.5939 |
Schistosoma mansoni | tyrosine kinase | 0.007 | 0.0262 | 0.0262 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.007 | 0.0262 | 0.0262 |
Onchocerca volvulus | 0.0044 | 0.0059 | 0.0497 | |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.007 | 0.0262 | 0.0262 |
Schistosoma mansoni | septate junction protein | 0.0119 | 0.0654 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0437 | 0.0417 |
Echinococcus multilocularis | leucine rich repeat containing protein 4 | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | cell adhesion molecule | 0.0119 | 0.0654 | 0.0654 |
Schistosoma mansoni | tyrosine kinase | 0.0155 | 0.0943 | 0.0943 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0387 | 0.2802 | 0.2802 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0092 | 0.0437 | 0.0437 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Schistosoma mansoni | cell adhesion molecule | 0.0478 | 0.3535 | 0.3535 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0063 | 0.0207 | 0.0207 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.004 | 0.0021 | 0.0021 |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0092 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0505 | 0.3752 | 0.3739 |
Schistosoma mansoni | tyrosine kinase | 0.004 | 0.0021 | 0.0021 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0049 | 0.0099 | 0.4755 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Brugia malayi | hypothetical protein | 0.0109 | 0.0576 | 0.0556 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.007 | 0.0262 | 0.0262 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.1286 | 1 | 1 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.1286 | 1 | 1 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0055 | 0.0141 | 0.0141 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0092 | 0.0437 | 0.0437 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Schistosoma mansoni | titin | 0.0136 | 0.0792 | 0.0792 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0043 | 0.0048 | 0.0048 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0049 | 0.0099 | 0.0271 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0066 | 0.0235 | 0.0235 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Toxoplasma gondii | hypothetical protein | 0.0039 | 0.002 | 0.0054 |
Trichomonas vaginalis | STE family protein kinase | 0.0154 | 0.0941 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0049 | 0.0099 | 0.1007 |
Echinococcus multilocularis | roundabout 2 | 0.0505 | 0.3752 | 0.3752 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Loa Loa (eye worm) | LAD-2 short isoform | 0.0092 | 0.0437 | 0.0417 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0654 | 0.0634 |
Toxoplasma gondii | NIMA-related protein kinase NIMA1 | 0.0154 | 0.0941 | 0.2584 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | roundabout 2 | 0.0119 | 0.0654 | 0.0654 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0049 | 0.0099 | 0.0099 |
Echinococcus multilocularis | roundabout 2 | 0.0119 | 0.0654 | 0.0654 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.007 | 0.0262 | 0.0262 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.007 | 0.0262 | 0.0262 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.004 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | TK protein kinase | 0.0063 | 0.0207 | 0.0187 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.007 | 0.0262 | 0.0262 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.008 | 0.0348 | 0.4245 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0066 | 0.0235 | 0.0235 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0049 | 0.0099 | 0.0271 |
Echinococcus granulosus | twitchin | 0.0415 | 0.3025 | 0.3025 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0099 | 0.0857 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0099 | 0.0857 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.2802 | 0.2787 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Brugia malayi | hypothetical protein | 0.0387 | 0.2802 | 0.2787 |
Schistosoma mansoni | cell adhesion molecule | 0.0092 | 0.0437 | 0.0437 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0055 | 0.0141 | 0.0121 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Echinococcus multilocularis | pro neuregulin 2, membrane bound | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0119 | 0.0654 | 0.0654 |
Schistosoma mansoni | cell adhesion molecule | 0.0119 | 0.0654 | 0.0654 |
Brugia malayi | basement membrane proteoglycan | 0.0092 | 0.0437 | 0.0417 |
Giardia lamblia | Kinase, NEK | 0.0154 | 0.0941 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0478 | 0.3535 | 0.3535 |
Schistosoma mansoni | peroxidasin | 0.0092 | 0.0437 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.2802 | 0.2787 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0514 | 0.3824 | 0.3811 |
Echinococcus granulosus | tyrosine protein kinase otk | 0.0119 | 0.0654 | 0.0654 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0136 | 0.0792 | 1 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0437 | 0.0437 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0055 | 0.0141 | 0.0141 |
Schistosoma mansoni | netrin receptor unc5 | 0.0092 | 0.0437 | 0.0437 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0492 | 0.3641 | 1 |
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0092 | 0.0437 | 0.0437 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0119 | 0.0654 | 0.0634 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Schistosoma mansoni | basigin related | 0.0092 | 0.0437 | 0.0437 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0055 | 0.0141 | 0.0388 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0055 | 0.0141 | 0.1322 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0055 | 0.0141 | 0.0388 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.007 | 0.0262 | 0.0262 |
Brugia malayi | Immunoglobulin domain containing protein | 0.0092 | 0.0437 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0387 | 0.2802 | 0.2787 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.11 uM | Inhibition of human beta-secretase | ChEMBL. | 14643321 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.