Detailed information for compound 278863

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 256.257 | Formula: C14H12N2O3
  • H donors: 0 H acceptors: 2 LogP: 1.43 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CCCOC(c1ccc2c(c1)OCO2)C(=C)C#N
  • InChi: 1S/C14H12N2O3/c1-10(8-16)14(17-6-2-5-15)11-3-4-12-13(7-11)19-9-18-12/h3-4,7,14H,1-2,6,9H2
  • InChiKey: SRYWMBABWVZHCG-UHFFFAOYSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0081
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Trichomonas vaginalis heat shock protein, putative 0.0051 0.0616 0.1718
Schistosoma mansoni heat shock protein 0.0064 0.0811 0.0807
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0139 0.0137
Trypanosoma cruzi heat shock protein 90, putative 0.0064 0.0811 1
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0045 0.0044
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0051 0.0616 1
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0013 0.005 0.0562
Chlamydia trachomatis DNA gyrase subunit B 0.0013 0.005 0.5
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0051 0.0616 0.7586
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0026 0.0246 0.0245
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0003 0.0004
Schistosoma mansoni cpg binding protein 0.0028 0.0277 0.0274
Echinococcus multilocularis neuropeptide FF receptor 2 0.0013 0.0045 0.0044
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0013 0.005 0.0562
Toxoplasma gondii heat shock protein HSP90 0.0064 0.0811 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0013 0.0045 0.0044
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0139 0.0299
Schistosoma mansoni hypothetical protein 0.0013 0.0045 0.0042
Onchocerca volvulus 0.0048 0.0564 0.1677
Trypanosoma cruzi heat shock protein, putative 0.0026 0.0246 0.3005
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Trypanosoma cruzi heat shock protein 90, putative 0.0051 0.0616 0.7586
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Schistosoma mansoni growth hormone secretagogue receptor 0.0013 0.0045 0.0042
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0045 0.0095
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.1553 0.1551
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0003 0.0002
Toxoplasma gondii heat shock protein 75, putative 0.0026 0.0246 0.3005
Schistosoma mansoni loxhd1 0.0019 0.0139 0.0135
Onchocerca volvulus 0.0013 0.0045 0.0125
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0303 0.03
Echinococcus multilocularis heat shock protein 90 0.0051 0.0616 0.0614
Trypanosoma brucei developmentally regulated phosphoprotein 0.0013 0.005 0.0562
Schistosoma mansoni neuropeptide receptor 0.0013 0.0045 0.0042
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0013 0.0045 0.0044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Plasmodium vivax SET domain protein, putative 0.003 0.0303 0.333
Leishmania major DNA topoisomerase ii 0.0013 0.005 0.0562
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0196 0.2774 0.2772
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0026 0.0246 0.0727
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0003 0.0008
Schistosoma mansoni neuropeptide receptor 0.0013 0.0045 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0003 0.0008
Echinococcus multilocularis RUN 0.0019 0.0139 0.0137
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Echinococcus multilocularis G protein coupled receptor 139 0.0013 0.0045 0.0044
Echinococcus granulosus dro:myosuppressin receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis neuropeptide s receptor 0.0013 0.0045 0.0044
Brugia malayi hypothetical protein 0.0019 0.0139 0.0303
Loa Loa (eye worm) hypothetical protein 0.0049 0.0582 0.1267
Entamoeba histolytica hypothetical protein 0.0036 0.0384 0.4392
Brugia malayi Hsp90 protein 0.0026 0.0246 0.0538
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0067 0.0143
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0013 0.0045 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Leishmania major hypothetical protein, conserved 0.0013 0.005 0.0562
Schistosoma mansoni hypothetical protein 0.0027 0.0255 0.0251
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0139 0.1667
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0045 0.0095
Trypanosoma brucei DNA topoisomerase ii 0.0013 0.005 0.0562
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0003 0.0008
Onchocerca volvulus 0.0235 0.3347 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0086
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.0053 0.0635 0.1383
Brugia malayi RE15519p 0.0013 0.0045 0.0099
Onchocerca volvulus 0.0013 0.0045 0.0125
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0139 0.0137
Onchocerca volvulus 0.0049 0.0582 0.173
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0013 0.0045 0.0044
Brugia malayi G protein-coupled receptor 0.0013 0.0045 0.0099
Plasmodium vivax metacaspase 1, putative 0.0053 0.0635 0.7697
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0003 0.0008
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0013 0.0045 0.0095
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0045 0.0042
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Echinococcus multilocularis G-protein coupled receptor, putative 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0013 0.0045 0.0044
Echinococcus granulosus sex peptide receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.115 0.2508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0013 0.0045 0.0042
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0582 0.0579
Schistosoma mansoni amine GPCR 0.0013 0.0045 0.0042
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0013 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0044 0.0513 0.1116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0003 0.0002
Trypanosoma cruzi metacaspase, putative 0.0053 0.0635 0.7826
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0003 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0045 0.0044
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0087 0.019
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0013 0.0045 0.0125
Schistosoma mansoni caspase-7 (C14 family) 0.0053 0.0635 0.0632
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0317 0.3885
Echinococcus granulosus somatostatin receptor 0.0013 0.0045 0.0044
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0086
Echinococcus granulosus G protein coupled receptor 139 0.0013 0.0045 0.0044
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0045 0.0095
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0139 0.1171
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0384 0.0382
Brugia malayi Melatonin receptor type 1A 0.0013 0.0045 0.0099
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0086
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0334 0.4095
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0003 0.0002
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0013 0.005 0.0048
Echinococcus granulosus dna polymerase eta 0.0044 0.0513 0.0512
Leishmania major DNA polymerase eta, putative 0.0044 0.0513 0.6311
Loa Loa (eye worm) hypothetical protein 0.0087 0.115 0.2508
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0045 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0139 0.0137
Echinococcus granulosus neuropeptide receptor 0.0013 0.0045 0.0044
Brugia malayi intermediate filament protein 0.0027 0.0251 0.0548
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0087 0.0187
Loa Loa (eye worm) hypothetical protein 0.003 0.0303 0.0658
Onchocerca volvulus 0.0013 0.0045 0.0125
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Schistosoma mansoni neuropeptide receptor 0.0013 0.0045 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0003 0.0004
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0013 0.0045 0.0042
Trypanosoma brucei heat shock protein 84, putative 0.0026 0.0246 0.3005
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis neuropeptide receptor A26 0.0013 0.0045 0.0044
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0013 0.0045 0.0044
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus granulosus lamin dm0 0.0027 0.0251 0.025
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0513 0.6311
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0303 0.0301
Onchocerca volvulus 0.0013 0.0045 0.0125
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0087 0.1029
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0334 0.4095
Loa Loa (eye worm) hypothetical protein 0.0013 0.005 0.0104
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0026 0.0246 0.0245
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus granulosus neuropeptide receptor A26 0.0013 0.0045 0.0044
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Echinococcus multilocularis caspase 8 0.0053 0.0635 0.0634
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Onchocerca volvulus 0.0027 0.0251 0.0741
Trypanosoma cruzi metacaspase 5, putative 0.0053 0.0635 0.7826
Echinococcus granulosus peptide allatostatin:somatostatin 0.0013 0.0045 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Echinococcus granulosus heat shock protein 90 0.0064 0.0811 0.0809
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0811 1
Leishmania major metacaspase, putative 0.0053 0.0635 0.7826
Onchocerca volvulus 0.0013 0.0045 0.0125
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0003 0.0008
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0003 0.0004
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0013 0.005 0.0138
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0139 0.0135
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0246 0.0597
Brugia malayi AKH receptor 0.0013 0.0045 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Loa Loa (eye worm) endoplasmin 0.0064 0.0811 0.1766
Loa Loa (eye worm) hypothetical protein 0.0019 0.0139 0.0299
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0251 0.0545
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Echinococcus multilocularis sex peptide receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0013 0.0045 0.0095
Onchocerca volvulus 0.0013 0.0045 0.0125
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Onchocerca volvulus 0.0013 0.0045 0.0125
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0013 0.005 0.0741
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0045 0.0042
Brugia malayi Pre-SET motif family protein 0.003 0.0303 0.0661
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi hypothetical protein 0.0036 0.0384 0.0838
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0635 0.7826
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0013 0.0045 0.0099
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi ORL1-like opioid receptor 0.0013 0.0045 0.0099
Schistosoma mansoni caspase-7 (C14 family) 0.0196 0.2774 0.2771
Echinococcus multilocularis dro:myosuppressin receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0046 0.0045
Brugia malayi ecdysteroid receptor 0.001 0.0003 0.0008
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0087 0.1029
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0346 0.0755
Echinococcus granulosus expressed protein 0.0033 0.0346 0.0344
Chlamydia trachomatis DNA gyrase subunit B 0.0013 0.005 0.5
Onchocerca volvulus 0.0013 0.0045 0.0125
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0045 0.0042
Brugia malayi hypothetical protein 0.0027 0.0255 0.0556
Schistosoma mansoni biogenic amine receptor 0.0013 0.0045 0.0042
Onchocerca volvulus 0.0013 0.0045 0.0125
Brugia malayi Probable DNA topoisomerase II 0.0013 0.005 0.0108
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0384 0.038
Schistosoma mansoni opsin-like receptor 0.0013 0.0045 0.0042
Schistosoma mansoni caspase-3 (C14 family) 0.0196 0.2774 0.2771
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.0419 0.5144
Onchocerca volvulus Neuropeptide F receptor homolog 0.0013 0.0045 0.0125
Onchocerca volvulus 0.0013 0.0045 0.0125
Echinococcus multilocularis expressed protein 0.0033 0.0346 0.0344
Echinococcus granulosus FTZ F1 alpha 0.001 0.0003 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0087 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0051 0.0575
Echinococcus multilocularis musashi 0.0027 0.0251 0.025
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0246 0.2588
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0303 0.0301
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0053 0.0635 0.0632
Echinococcus multilocularis protein quaking 0.0027 0.0255 0.0253
Giardia lamblia Heat shock protein HSP 90-alpha 0.0051 0.0616 0.7443
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Trichomonas vaginalis heat shock protein, putative 0.0064 0.0811 0.2308
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Echinococcus granulosus fmrfamide receptor 0.0013 0.0045 0.0044
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0334 0.4095
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0139 0.1573
Brugia malayi G-protein coupled receptor 0.0013 0.0045 0.0099
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Schistosoma mansoni hypothetical protein 0.0013 0.0045 0.0042
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0013 0.005 0.0562
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0045 0.0042
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0045 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0051 0.0616 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi nuclear receptor NHR-88 0.001 0.0003 0.0008
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0139 0.1172
Brugia malayi heat shock protein 90 0.0064 0.0811 0.1769
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.1029
Echinococcus granulosus tachykinin peptides receptor 99D 0.0013 0.0045 0.0044
Echinococcus granulosus heat shock protein 0.0064 0.0811 0.0809
Brugia malayi sulfakinin receptor protein 0.0013 0.0045 0.0099
Onchocerca volvulus 0.003 0.0303 0.0896
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.005 0.5
Echinococcus granulosus g protein coupled receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0045 0.0044
Echinococcus multilocularis serotonin receptor 0.0013 0.0045 0.0044
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0334 0.4095
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0635 0.1777
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0013 0.005 0.0108
Trypanosoma cruzi metacaspase, putative 0.0053 0.0635 0.7826
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0811 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0277 0.0601
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0564 0.1231
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0303 0.0301
Loa Loa (eye worm) hypothetical protein 0.0027 0.0251 0.0545
Echinococcus granulosus heat shock protein 90 0.0051 0.0616 0.0614
Echinococcus granulosus serotonin receptor 0.0013 0.0045 0.0044
Schistosoma mansoni neuropeptide receptor 0.0013 0.0045 0.0042
Toxoplasma gondii Hsp90 domain-containing protein 0.0026 0.0246 0.3005
Trypanosoma brucei metacaspase MCA2 0.0053 0.0635 0.7826
Schistosoma mansoni amine GPCR 0.0013 0.0045 0.0042
Trypanosoma cruzi metacaspase, putative 0.0053 0.0635 0.7826
Loa Loa (eye worm) heat shock protein 75 0.0026 0.0246 0.0534
Plasmodium vivax endoplasmin, putative 0.0064 0.0811 1
Trichomonas vaginalis set domain proteins, putative 0.0235 0.3347 1
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0087 0.1029
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Trypanosoma cruzi heat shock protein 85, putative 0.0051 0.0616 0.7586
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0013 0.0045 0.0042
Schistosoma mansoni opsin-like receptor 0.0013 0.0045 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0051 0.0575
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0013 0.0045 0.0044
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.1029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0045 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0013 0.0045 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0303 0.03
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0635 0.7826
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Schistosoma mansoni intermediate filament proteins 0.0027 0.0251 0.0248
Onchocerca volvulus 0.0019 0.0139 0.0405
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Leishmania major mitochondrial DNA topoisomerase II 0.0013 0.005 0.0562
Brugia malayi Cell death protein 3 precursor 0.0053 0.0635 0.1386
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0635 0.7826
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0013 0.005 0.0138
Brugia malayi G protein-coupled receptor F59B2.13 0.0013 0.0045 0.0099
Schistosoma mansoni adenoreceptor 0.0013 0.0045 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Onchocerca volvulus 0.0013 0.0045 0.0125
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0013 0.0045 0.0099
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0139 0.1667
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Schistosoma mansoni lipoxygenase 0.008 0.1042 0.1039
Echinococcus multilocularis cpg binding protein 0.003 0.0301 0.03
Schistosoma mansoni hypothetical protein 0.0405 0.5868 0.5867
Entamoeba histolytica heat shock protein 90, putative 0.0064 0.0811 1
Trypanosoma brucei unspecified product 0.0019 0.0139 0.1667
Schistosoma mansoni endoplasmin 0.0064 0.0811 0.0807
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0139 0.027
Echinococcus multilocularis lamin 0.0027 0.0251 0.025
Schistosoma mansoni polycystin 1-related 0.0019 0.0139 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0139 0.1573
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0051 0.0616 1
Plasmodium falciparum metacaspase 1 0.0053 0.0635 0.7697
Plasmodium falciparum metacaspase-like protein 0.0053 0.0635 0.7697
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0003 0.0008
Trypanosoma brucei unspecified product 0.0013 0.0051 0.0575
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0013 0.0045 0.0095
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0334 0.4095
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0003 0.0002
Schistosoma mansoni endoplasmin 0.0064 0.0811 0.0807
Trypanosoma cruzi Heat shock protein 83, putative 0.0064 0.0811 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0513 0.6311
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0003 0.0002
Giardia lamblia Heat shock protein HSP 90-alpha 0.0064 0.0811 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0003 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0003 0.0004
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0045 0.0044
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0013 0.0045 0.0099
Echinococcus granulosus caspase 8 0.0053 0.0635 0.0634
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0003 0.0008
Onchocerca volvulus 0.0013 0.0045 0.0125
Brugia malayi Dopamine receptor protein 2 0.0013 0.0045 0.0099
Echinococcus granulosus cpg binding protein 0.003 0.0301 0.03
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0334 0.3743
Echinococcus granulosus 7TM GPCR rhodopsin 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0003 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0139 0.1667
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0045 0.0042
Plasmodium vivax heat shock protein 86, putative 0.0064 0.0811 1
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Giardia lamblia DINP protein human, muc B family 0.0019 0.0139 0.1171
Entamoeba histolytica hypothetical protein 0.0036 0.0384 0.4392
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0003 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0051 0.0575
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Echinococcus granulosus tumor protein p63 0.0334 0.4822 0.4822
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0087 0.0086
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0013 0.005 0.0562
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0013 0.0045 0.0099
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0053 0.0635 0.1386
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0251 0.0548
Toxoplasma gondii DNA topoisomerase 2, putative 0.0013 0.005 0.0562
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0003 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0045 0.0044
Schistosoma mansoni DNA topoisomerase II 0.0013 0.005 0.0046
Onchocerca volvulus 0.0013 0.0045 0.0125
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0045 0.0044
Trypanosoma brucei heat shock protein 90, putative 0.0064 0.0811 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Leishmania major heat shock protein, putative 0.0026 0.0246 0.3005
Schistosoma mansoni eyes absent homolog 0.0087 0.115 0.1147
Trypanosoma cruzi DNA topoisomerase II, putative 0.0013 0.005 0.0562
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0303 0.03
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0513 0.112
Echinococcus multilocularis allatostatin A receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0767 0.0763
Schistosoma mansoni lamin 0.0027 0.0251 0.0248
Leishmania major developmentally regulated phosphoprotein-like protein 0.0013 0.005 0.0562
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0051 0.0616 0.0614
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0317 0.3885
Brugia malayi G-protein coupled receptor 0.0013 0.0045 0.0099
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0087 0.1029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0003 0.0004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.2924 0.6379
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0013 0.0045 0.0042
Schistosoma mansoni cpg binding protein 0.003 0.0301 0.0298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0013 0.0045 0.0044
Echinococcus granulosus neuropeptide receptor 0.0013 0.0045 0.0044
Echinococcus granulosus g-protein coupled receptor 0.0013 0.0045 0.0044
Giardia lamblia Grp94/Hsp90 0.0051 0.0616 0.7443
Brugia malayi Tachykinin-like peptides receptor 99D 0.0013 0.0045 0.0099
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0013 0.0045 0.0042
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus granulosus neuropeptide s receptor 0.0013 0.0045 0.0044
Leishmania major DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Echinococcus granulosus dna polymerase kappa 0.0019 0.0139 0.0137
Trypanosoma brucei heat shock protein 90, putative 0.0064 0.0811 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0003 0.0002
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.1553 0.1551
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0003 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Schistosoma mansoni hypothetical protein 0.0036 0.0384 0.038
Echinococcus multilocularis caspase 3 0.0144 0.1993 0.1992
Loa Loa (eye worm) hypothetical protein 0.0013 0.005 0.0104
Toxoplasma gondii heat shock protein 90, putative 0.0064 0.0811 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Trypanosoma brucei metacaspase MCA3 0.0053 0.0635 0.7826
Echinococcus granulosus caspase 0.0196 0.2774 0.2772
Plasmodium vivax hypothetical protein, conserved 0.0053 0.0635 0.7697
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0139 0.0137
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Onchocerca volvulus 0.0013 0.0045 0.0125
Schistosoma mansoni alpha-1 adrenergic receptor 0.0013 0.0045 0.0042
Loa Loa (eye worm) heat shock protein 90 0.0064 0.0811 0.1766
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Brugia malayi larval opioid receptor 0.0013 0.0045 0.0099
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0139 0.0137
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0067 0.0147
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.5868 0.5867
Schistosoma mansoni hypothetical protein 0.0027 0.0255 0.0251
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0045 0.0042
Echinococcus multilocularis tumor protein p63 0.0334 0.4822 0.4822
Echinococcus granulosus hypothetical protein 0.0013 0.0045 0.0044
Trypanosoma cruzi metacaspase 5, putative 0.0053 0.0635 0.7826
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0003 0.0002
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0013 0.005 0.0562
Onchocerca volvulus 0.0013 0.0045 0.0125
Echinococcus granulosus g protein coupled receptor 0.0013 0.0045 0.0044
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0087 0.1029
Loa Loa (eye worm) hypothetical protein 0.0013 0.005 0.0104
Brugia malayi nuclear hormone receptor 0.001 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0003 0.0008
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0045 0.0044
Schistosoma mansoni amine GPCR 0.0013 0.0045 0.0042
Trypanosoma brucei Heat shock protein 83, putative 0.0064 0.0811 1
Treponema pallidum heat shock protein 90 0.0051 0.0616 1
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0013 0.0045 0.0044
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Echinococcus multilocularis dna polymerase eta 0.0044 0.0513 0.0512
Echinococcus granulosus allatostatin A receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0003 0.0008
Brugia malayi putative neuropeptide receptor 0.0013 0.0045 0.0099
Schistosoma mansoni pyruvate dehydrogenase 0.0013 0.005 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0441 0.1188
Schistosoma mansoni hypothetical protein 0.0048 0.0564 0.0561
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0139 0.0137
Schistosoma mansoni amine GPCR 0.0013 0.0045 0.0042
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0013 0.0045 0.0044
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Echinococcus granulosus dnaJ subfamily B 0.0405 0.5868 0.5867
Loa Loa (eye worm) hypothetical protein 0.0026 0.0244 0.0529
Echinococcus multilocularis somatostatin receptor 0.0013 0.0045 0.0044
Schistosoma mansoni hypothetical protein 0.0013 0.0045 0.0042
Brugia malayi steroid hormone receptor 0.001 0.0003 0.0008
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0013 0.005 0.0741
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0045 0.0095
Brugia malayi Temporarily assigned gene name protein 44 0.0027 0.0255 0.0556
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0013 0.005 0.0562
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0045 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis endoplasmin 0.0051 0.0616 0.0614
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.3331 0.333
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Brugia malayi follicle stimulating hormone receptor 0.0013 0.0045 0.0099
Brugia malayi GnHR receptor homolog 0.0013 0.0045 0.0099
Echinococcus granulosus lamin 0.0027 0.0251 0.025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0255 0.0553
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0045 0.0044
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0045 0.0042
Trichomonas vaginalis rotamase, putative 0.0033 0.0346 0.0899
Schistosoma mansoni survival motor neuron protein 0.0048 0.0564 0.0561
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0139 0.027
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0346 0.0752
Trichomonas vaginalis endoplasmin, putative 0.0039 0.0441 0.1188
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0045 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0635 0.1777
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0139 0.0137
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0013 0.005 0.0562
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0013 0.005 0.0108
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0139 0.1573
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0003 0.0002
Trypanosoma cruzi metacaspase, putative 0.0053 0.0635 0.7826
Brugia malayi hypothetical protein 0.0019 0.0139 0.0303
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0045 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0003 0.0008
Schistosoma mansoni heat shock protein 0.0064 0.0811 0.0807
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0139 0.0302
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Echinococcus multilocularis caspase 0.0196 0.2774 0.2772
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.3331 0.333
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0087 0.0495
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0139 0.1667
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0013 0.005 0.0048
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Trypanosoma brucei metacaspase 5, putative 0.0053 0.0635 0.7826
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0026 0.0246 0.2588
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0139 0.0135
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0004
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Mycobacterium ulcerans heat shock protein 90 0.0051 0.0616 1
Entamoeba histolytica hypothetical protein 0.0036 0.0384 0.4392
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0013 0.005 0.0048
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Leishmania major DNA polymerase eta, putative 0.0031 0.0317 0.3885
Echinococcus multilocularis orexin receptor type 2 0.0013 0.0045 0.0044
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0139 0.1172
Plasmodium falciparum endoplasmin, putative 0.0039 0.0441 0.5145
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Echinococcus granulosus g protein coupled receptor 0.0013 0.0045 0.0044
Onchocerca volvulus Cell death protein 3 homolog 0.0053 0.0635 0.189
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0013 0.005 0.0562
Loa Loa (eye worm) tumor suppressor 0.0318 0.4583 1
Brugia malayi Pre-SET motif family protein 0.0206 0.2924 0.638
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0013 0.0045 0.0095
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0087 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0635 0.1777
Brugia malayi Endoplasmin precursor 0.0064 0.0811 0.1769
Trichomonas vaginalis heat shock protein, putative 0.0051 0.0616 0.1718
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0013 0.0045 0.0044
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Onchocerca volvulus 0.0027 0.0251 0.0741
Loa Loa (eye worm) hypothetical protein 0.0019 0.0139 0.0299
Schistosoma mansoni cpg binding protein 0.003 0.0301 0.0298
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0346 0.0899
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0013 0.0045 0.0042
Trypanosoma brucei metacaspase 0.0053 0.0635 0.7826
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0003 0.0004
Brugia malayi putative neuropeptide receptor NPR1 0.0013 0.0045 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0635 0.1777
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0384 0.0382
Brugia malayi neuropeptide F receptor 0.0013 0.0045 0.0099
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) TOPoisomerase family member 0.0013 0.005 0.0104
Schistosoma mansoni DNA polymerase eta 0.0044 0.0513 0.051
Echinococcus granulosus intermediate filament protein 0.0027 0.0251 0.025
Plasmodium falciparum heat shock protein 90 0.0064 0.0811 1
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0246 0.2588
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0303 0.3705
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0003 0.0004
Schistosoma mansoni rab6-interacting 0.0019 0.0139 0.0135
Echinococcus granulosus endoplasmin 0.0051 0.0616 0.0614
Entamoeba histolytica heat shock protein 90, putative 0.0064 0.0811 1
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0013 0.0045 0.0042
Trichomonas vaginalis rotamase, putative 0.0032 0.0334 0.0864
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0251 0.0545
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Onchocerca volvulus 0.0028 0.0277 0.0819
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0045 0.0044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0003 0.0002
Schistosoma mansoni amine GPCR 0.0013 0.0045 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0045 0.0044
Schistosoma mansoni lipoxygenase 0.0114 0.1553 0.155
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0013 0.0045 0.0099
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0139 0.0137
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0139 0.0299
Brugia malayi Dopamine receptor 0.0013 0.0045 0.0099
Brugia malayi tumor suppressor. 0.0318 0.4583 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0278 0.0276
Schistosoma mansoni opsin-like receptor 0.0013 0.0045 0.0042
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0013 0.005 0.0048
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0013 0.005 0.0138
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Schistosoma mansoni biogenic amine receptor 0.0013 0.0045 0.0042
Schistosoma mansoni rotamase 0.0033 0.0346 0.0343
Onchocerca volvulus 0.0013 0.0045 0.0125
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0003 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0045 0.0044
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Echinococcus multilocularis microtubule associated protein 2 0.0683 1 1
Brugia malayi Doublecortin family protein 0.0019 0.0139 0.0303
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Trichomonas vaginalis heat shock protein, putative 0.0051 0.0616 0.1718
Loa Loa (eye worm) melatonin receptor type 1A 0.0013 0.0045 0.0095
Echinococcus granulosus hypothetical protein 0.0027 0.0255 0.0253
Trypanosoma cruzi DNA topoisomerase II, putative 0.0013 0.005 0.0562
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0013 0.0045 0.0042
Echinococcus granulosus caspase 3 0.0144 0.1993 0.1992
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0635 0.1777
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Schistosoma mansoni heat shock protein 0.0026 0.0246 0.0243
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0013 0.005 0.0741
Brugia malayi CXXC zinc finger family protein 0.0028 0.0277 0.0605
Schistosoma mansoni neuropeptide f receptor 76f 0.0013 0.0045 0.0042
Schistosoma mansoni myosin xvIII 0.0013 0.0045 0.0042
Brugia malayi hypothetical protein 0.0087 0.115 0.251
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Brugia malayi isocitrate dehydrogenase 0.0016 0.0087 0.019
Leishmania major heat shock protein 83-1 0.0064 0.0811 1
Brugia malayi Dopamine receptor protein 1 0.0013 0.0045 0.0099
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0671 0.8268
Loa Loa (eye worm) hypothetical protein 0.0053 0.0635 0.1383
Echinococcus multilocularis caspase 2 0.0053 0.0635 0.0634
Echinococcus granulosus caspase 2 0.0053 0.0635 0.0634
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0013 0.0045 0.0095
Schistosoma mansoni histamine h1 receptor 0.0013 0.0045 0.0042
Echinococcus multilocularis heat shock protein 0.0064 0.0811 0.0809
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0013 0.005 0.0562
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0303 0.03
Echinococcus granulosus neuropeptide FF receptor 2 0.0013 0.0045 0.0044
Echinococcus granulosus protein quaking 0.0027 0.0255 0.0253
Brugia malayi kinase, mitochondrial precursor 0.0013 0.005 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Onchocerca volvulus 0.0019 0.0139 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Brugia malayi Serotonin receptor 0.0013 0.0045 0.0099
Brugia malayi neuropeptide F receptor 0.0013 0.0045 0.0099
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0003 0.0008
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0013 0.005 0.0562
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Loa Loa (eye worm) hypothetical protein 0.0013 0.0046 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0003 0.0008
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0087 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0139 0.1667
Schistosoma mansoni rab6-interacting 0.0019 0.0139 0.0135
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus granulosus alpha 1A adrenergic receptor 0.0013 0.0045 0.0044
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0013 0.0045 0.0044
Brugia malayi hypothetical protein 0.0234 0.3331 0.7269
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0045 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0045 0.0042
Plasmodium vivax heat shock protein 90, putative 0.0026 0.0246 0.2588
Trypanosoma brucei heat shock protein, putative 0.0064 0.0811 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0635 0.1777
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0196 0.2774 0.2772
Echinococcus granulosus RUN 0.0019 0.0139 0.0137
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0045 0.0042
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0087 0.0664
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0139 0.0137
Trypanosoma brucei unspecified product 0.0013 0.0051 0.0575
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0087 0.0084
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0045 0.0044
Trypanosoma brucei Metacaspase-4 0.0053 0.0635 0.7826
Brugia malayi Serotonin receptor 0.0013 0.0045 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0635 0.1777
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0045 0.0044
Echinococcus multilocularis heat shock protein 90 0.0064 0.0811 0.0809
Onchocerca volvulus 0.0013 0.0045 0.0125
Schistosoma mansoni biogenic amine receptor 0.0013 0.0045 0.0042
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0811 1
Echinococcus multilocularis g-protein coupled receptor 0.0013 0.0045 0.0044
Echinococcus granulosus orexin receptor type 2 0.0013 0.0045 0.0044
Schistosoma mansoni microtubule-associated protein tau 0.0683 1 1
Plasmodium vivax heat shock protein, putative 0.0026 0.0246 0.2588
Schistosoma mansoni hypothetical protein 0.0019 0.0139 0.0135
Echinococcus multilocularis serotonin receptor 0.0013 0.0045 0.0044
Brugia malayi hypothetical protein 0.0013 0.0045 0.0099
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0139 0.1573
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0095
Echinococcus multilocularis lamin dm0 0.0027 0.0251 0.025
Entamoeba histolytica hypothetical protein 0.0036 0.0384 0.4392
Loa Loa (eye worm) hypothetical protein 0.0234 0.3331 0.7268
Schistosoma mansoni lamin 0.0027 0.0251 0.0248
Loa Loa (eye worm) TYRA-2 protein 0.0013 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0003 0.0008

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 In vivo anti-malarial activity against P. berghei in mice at a dose of 160 mg/kg; Active ChEMBL. 10201838
Inhibition (functional) 0 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 500 uM/well through Schizonts maturation assay over 24 hr; ND=No data ChEMBL. 10201838
Inhibition (functional) = 0 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 0.10 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 0 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 0.10 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 6 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 0.25 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 6 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 0.25 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 36 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 0.50 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 36 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 0.50 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 43 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 1 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 43 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 1 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 57 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 2.5 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 57 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 2.5 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 64 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 5 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 64 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 5 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 93 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 10 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 93 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 10 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 100 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 100 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 100 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 50 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 100 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 20 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 100 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 100 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 100 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 50 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Inhibition (functional) = 100 % In vitro antimalarial activity of the compound against P. falciparum at a dose of 20 uM/well through Schizonts maturation assay over 24 hr ChEMBL. 10201838
Mean survival time (functional) = 7.8 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 20 mg/kg ChEMBL. 10201838
Mean survival time (functional) = 7.8 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 20 mg/kg ChEMBL. 10201838
Mean survival time (functional) = 9.2 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 40 mg/kg ChEMBL. 10201838
Mean survival time (functional) = 9.2 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 40 mg/kg ChEMBL. 10201838
Mean survival time (functional) = 11.4 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 80 mg/kg ChEMBL. 10201838
Mean survival time (functional) = 11.4 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 80 mg/kg ChEMBL. 10201838
Mean survival time (functional) = 14.2 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 160 mg/kg ChEMBL. 10201838
Mean survival time (functional) = 14.2 day Anti-malarial activity against P. berghei evaluated in terms of mean survival time for mice at a dose of 160 mg/kg ChEMBL. 10201838
PGI (functional) 0 % In vitro growth inhibition by the compound against P. falciparum at a dose of 25 uM/well through total parasite growth inhibition assay over 72h; ND=No data ChEMBL. 10201838
PGI (functional) = 0 % In vitro growth inhibition by the compound against P. falciparum at a dose of 0.25 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 0 % In vitro growth inhibition by the compound against P. falciparum at a dose of 0.25 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 10 % In vitro growth inhibition by the compound against P. falciparum at a dose of 0.5 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 10 % In vitro growth inhibition by the compound against P. falciparum at a dose of 0.5 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 25 % In vitro growth inhibition by the compound against P. falciparum at a dose of 1.0 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 25 % In vitro growth inhibition by the compound against P. falciparum at a dose of 1.0 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 40 % In vitro growth inhibition by the compound against P. falciparum at a dose of 2.5 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 40 % In vitro growth inhibition by the compound against P. falciparum at a dose of 2.5 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 52.5 % In vitro growth inhibition by the compound against P. falciparum at a dose of 5 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 52.5 % In vitro growth inhibition by the compound against P. falciparum at a dose of 5 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 90 % In vitro growth inhibition by the compound against P. falciparum at a dose of 10 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 90 % In vitro growth inhibition by the compound against P. falciparum at a dose of 10 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 95 % In vitro growth inhibition by the compound against P. falciparum at a dose of 20 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 95 % In vitro growth inhibition by the compound against P. falciparum at a dose of 20 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 100 % In vitro growth inhibition by the compound against P. falciparum at a dose of 100 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 100 % In vitro growth inhibition by the compound against P. falciparum at a dose of 50 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 100 % In vitro growth inhibition by the compound against P. falciparum at a dose of 100 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838
PGI (functional) = 100 % In vitro growth inhibition by the compound against P. falciparum at a dose of 50 uM/well through total parasite growth inhibition assay over 72 hr ChEMBL. 10201838

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.