Detailed information for compound 309650

Basic information

Technical information
  • TDR Targets ID: 309650
  • Name: (Z)-1-(5-pyridin-2-yl-1,3-oxazol-2-yl)octadec -9-en-1-ol
  • MW: 412.608 | Formula: C26H40N2O2
  • H donors: 1 H acceptors: 3 LogP: 8.05 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCC/C=C\CCCCCCCC(c1ncc(o1)c1ccccn1)O
  • InChi: 1S/C26H40N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(29)26-28-22-25(30-26)23-19-17-18-21-27-23/h9-10,17-19,21-22,24,29H,2-8,11-16,20H2,1H3/b10-9-
  • InChiKey: HMCTTYLXWCOQBU-KTKRTIGZSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (Z)-1-[5-(2-pyridyl)oxazol-2-yl]octadec-9-en-1-ol
  • (Z)-1-[5-(2-pyridyl)-2-oxazolyl]-9-octadecen-1-ol
  • (Z)-1-[5-(2-pyridyl)-2-oxazolyl]octadec-9-en-1-ol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Anandamide amidohydrolase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W) Get druggable targets OG5_127783 All targets in OG5_127783
Echinococcus granulosus fatty acid amide hydrolase 1 Get druggable targets OG5_127783 All targets in OG5_127783
Candida albicans hypothetical protein Get druggable targets OG5_127783 All targets in OG5_127783
Schistosoma japonicum Fatty-acid amide hydrolase 1, putative Get druggable targets OG5_127783 All targets in OG5_127783
Schistosoma japonicum ko:K01175 fatty acid amide hydrolase [EC:3.1.-.-], putative Get druggable targets OG5_127783 All targets in OG5_127783
Echinococcus granulosus fatty acid amide hydrolase 1 Get druggable targets OG5_127783 All targets in OG5_127783
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127783 All targets in OG5_127783
Schistosoma mansoni amidase Get druggable targets OG5_127783 All targets in OG5_127783
Echinococcus multilocularis fatty acid amide hydrolase 1 Get druggable targets OG5_127783 All targets in OG5_127783
Brugia malayi amidase Get druggable targets OG5_127783 All targets in OG5_127783
Candida albicans one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W) Get druggable targets OG5_127783 All targets in OG5_127783
Schistosoma mansoni fatty-acid amide hydrolase Get druggable targets OG5_127783 All targets in OG5_127783
Schistosoma japonicum Fatty-acid amide hydrolase 1, putative Get druggable targets OG5_127783 All targets in OG5_127783
Candida albicans one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W) Get druggable targets OG5_127783 All targets in OG5_127783
Echinococcus multilocularis fatty acid amide hydrolase 1 Get druggable targets OG5_127783 All targets in OG5_127783
Candida albicans one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W) Get druggable targets OG5_127783 All targets in OG5_127783
Candida albicans hypothetical protein Get druggable targets OG5_127783 All targets in OG5_127783
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Anandamide amidohydrolase   579 aa 539 aa 34.7 %
Echinococcus granulosus fatty acid amide hydrolase 1 Anandamide amidohydrolase   579 aa 470 aa 28.7 %
Schistosoma japonicum Fatty-acid amide hydrolase 1, putative Anandamide amidohydrolase   579 aa 499 aa 24.6 %
Echinococcus multilocularis fatty acid amide hydrolase 1 Anandamide amidohydrolase   579 aa 470 aa 28.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.1204 0.1204
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0006 0.0006
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus multilocularis allatostatin A receptor 0.08 0.6889 0.6889
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0052 0.0155
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0842 0.1286
Schistosoma mansoni amine GPCR 0.08 0.6889 0.6889
Onchocerca volvulus 0.0057 0.0369 0.0481
Schistosoma mansoni neuropeptide F-like receptor 0.08 0.6889 0.6889
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0053 0.0332 0.0489
Brugia malayi Protein kinase domain containing protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0325 0.2716 0.2716
Echinococcus granulosus g protein coupled receptor 0.08 0.6889 0.6889
Onchocerca volvulus 0.08 0.6889 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0198 0.0586
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0053 0.0332 1
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0842 1
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.08 0.6889 0.6889
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0775 0.1181
Loa Loa (eye worm) hypothetical protein 0.0035 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0371 0.055
Loa Loa (eye worm) neuropeptide F receptor 0.08 0.6889 0.6889
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Loa Loa (eye worm) PDE1B protein 0.1154 1 1
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0052 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0775 0.1181
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0053 0.0332 0.0986
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.1143 0.3392
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.08 0.6889 0.6889
Onchocerca volvulus 0.0035 0.017 0.0191
Leishmania major hypothetical protein, conserved 0.0035 0.017 0.0506
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Echinococcus granulosus microtubule associated protein 2 0.0726 0.6239 0.6239
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0006 0.0006
Echinococcus multilocularis neuropeptide FF receptor 2 0.08 0.6889 0.6889
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.004 0.004
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0896 0.7735 0.7735
Echinococcus multilocularis biogenic amine (5HT) receptor 0.08 0.6889 0.6889
Schistosoma mansoni lamin 0.0057 0.0369 0.0369
Brugia malayi G protein-coupled receptor F59B2.13 0.08 0.6889 0.6889
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0399 0.3371 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0489
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Schistosoma mansoni neuropeptide receptor 0.08 0.6889 0.6889
Trichomonas vaginalis esterase, putative 0.0035 0.017 0.0236
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0499 0.0499
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0006 0.0019
Echinococcus multilocularis RUN 0.002 0.004 0.004
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.08 0.6889 0.6889
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0135 0.0135
Echinococcus multilocularis g protein coupled receptor 0.08 0.6889 0.6889
Brugia malayi Dopamine receptor 0.08 0.6889 0.6889
Brugia malayi hypothetical protein 0.002 0.004 0.004
Loa Loa (eye worm) hypoxia-induced factor 1 0.0166 0.1326 0.1326
Schistosoma mansoni histamine h1 receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0006 0.0006
Loa Loa (eye worm) melatonin receptor type 1A 0.08 0.6889 0.6889
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Onchocerca volvulus 0.08 0.6889 1
Echinococcus granulosus rhodopsin orphan GPCR 0.08 0.6889 0.6889
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0443 0.3185
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0111 0.0838 0.2487
Echinococcus multilocularis fmrfamide receptor 0.08 0.6889 0.6889
Schistosoma mansoni biogenic amine (dopamine) receptor 0.08 0.6889 0.6889
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus granulosus alpha 1A adrenergic receptor 0.08 0.6889 0.6889
Schistosoma mansoni biogenic amine (dopamine) receptor 0.08 0.6889 0.6889
Echinococcus multilocularis lamin 0.0057 0.0369 0.0369
Echinococcus multilocularis fmrfamide receptor 0.08 0.6889 0.6889
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.1816 1
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.004 0.004
Echinococcus multilocularis G protein coupled receptor 139 0.08 0.6889 0.6889
Brugia malayi gonadotropin-releasing hormone receptor 2 0.08 0.6889 0.6889
Echinococcus multilocularis geminin 0.0187 0.151 0.151
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0332 0.0489
Brugia malayi beta-lactamase family protein 0.0035 0.017 0.017
Echinococcus granulosus somatostatin receptor 0.08 0.6889 0.6889
Echinococcus multilocularis dro:myosuppressin receptor 0.08 0.6889 0.6889
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0332 0.0489
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Echinococcus granulosus hypothetical protein 0.08 0.6889 0.6889
Mycobacterium tuberculosis Conserved protein 0.0035 0.017 0.0907
Echinococcus granulosus tm gpcr rhodopsin 0.08 0.6889 0.6889
Entamoeba histolytica hypothetical protein 0.0072 0.0499 0.5659
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0183 0.1471 0.1471
Schistosoma mansoni hypothetical protein 0.0035 0.0169 0.0169
Brugia malayi Pre-SET motif family protein 0.0094 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Brugia malayi G-protein coupled receptor 0.08 0.6889 0.6889
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0842 0.0842
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.08 0.6889 0.6889
Echinococcus multilocularis neuropeptide Y receptor 0.08 0.6889 0.6889
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.004 0.004
Brugia malayi isocitrate dehydrogenase 0.0016 0.0006 0.0006
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.017 0.0907
Plasmodium vivax hypothetical protein, conserved 0.0035 0.017 0.0506
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.069 0.069
Echinococcus multilocularis lamin dm0 0.0057 0.0369 0.0369
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.069 0.069
Loa Loa (eye worm) inositol-1 0.0038 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.1154 1 1
Brugia malayi Serotonin receptor 0.08 0.6889 0.6889
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0842 0.1286
Brugia malayi beta-lactamase family protein 0.0035 0.017 0.017
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0399 0.3371 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0052 0.0052
Schistosoma mansoni amidase 0.0123 0.0946 0.0946
Schistosoma mansoni hypothetical protein 0.0187 0.151 0.151
Echinococcus granulosus single minded 2 0.004 0.0214 0.0214
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus granulosus rhodopsin orphan GPCR 0.08 0.6889 0.6889
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.08 0.6889 0.6889
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0053 0.0332 0.0332
Leishmania major DNA polymerase eta, putative 0.0021 0.0052 0.0155
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0053 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Entamoeba histolytica hypothetical protein 0.0072 0.0499 0.5659
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Brugia malayi putative neuropeptide receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0006 0.0006
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0371 0.0371
Trichomonas vaginalis set domain proteins, putative 0.0745 0.6411 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Toxoplasma gondii hypothetical protein 0.0021 0.0049 0.0145
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0111 0.0838 0.2487
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.017 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0838 0.1281
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0052 0.0155
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0308 0.2566 0.7614
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0399 0.3371 1
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0842 0.0842
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0111 0.0838 0.1281
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0006 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0332 0.0489
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0986
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0006 0.0019
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.199 0.199
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0053 0.0332 0.0332
Echinococcus multilocularis serotonin receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.0053 0.0332 0.0332
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0489
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0332 0.0986
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0053 0.0332 0.0332
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0053 0.0332 0.0332
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.017 0.017
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0259 0.0374
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0006 0.0006
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0259 0.0259
Echinococcus granulosus GPCR family 2 0.0016 0.0006 0.0006
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.0775 0.2298
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0198 0.0586
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0129 0.0171
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0842 0.2498
Echinococcus granulosus lamin dm0 0.0057 0.0369 0.0369
Echinococcus multilocularis neuropeptide receptor A26 0.08 0.6889 0.6889
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0198 0.1201
Schistosoma mansoni intermediate filament proteins 0.0057 0.0369 0.0369
Echinococcus granulosus adenylate cyclase type IX 0.012 0.0919 0.0919
Schistosoma mansoni alpha-1 adrenergic receptor 0.08 0.6889 0.6889
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0489
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.08 0.6889 0.6889
Onchocerca volvulus 0.0094 0.069 0.0949
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.08 0.6889 0.6889
Echinococcus granulosus neuropeptide Y receptor 0.08 0.6889 0.6889
Echinococcus granulosus serotonin receptor 0.08 0.6889 0.6889
Schistosoma mansoni rab6-interacting 0.002 0.004 0.004
Echinococcus granulosus sex peptide receptor 0.08 0.6889 0.6889
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0198 0.0586
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.009 0.0655 0.0993
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0245 0.0726
Echinococcus granulosus neuropeptide receptor 0.08 0.6889 0.6889
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0842 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0842 0.2498
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.0035 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0094 0.069 0.069
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0052 0.0051
Onchocerca volvulus 0.0057 0.0369 0.0481
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.017 0.0506
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0085 0.0615 0.084
Toxoplasma gondii hypothetical protein 0.0058 0.0371 0.1101
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.1154 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.08 0.6889 0.6889
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0516 0.0777
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0053 0.0332 0.0332
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1054 0.9122 0.9122
Schistosoma mansoni neuropeptide receptor 0.08 0.6889 0.6889
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0108 0.0108
Schistosoma mansoni lipoxygenase 0.002 0.004 0.004
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0053 0.0332 0.0332
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.1288 0.708
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Loa Loa (eye worm) hypothetical protein 0.0082 0.0583 0.0583
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0111 0.0838 0.2487
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0226 0.6799
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0842 0.0842
Onchocerca volvulus 0.08 0.6889 1
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.0035 0.017 0.017
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0053 0.0332 0.0332
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.2566 0.7614
Echinococcus granulosus rhodopsin orphan GPCR 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Brugia malayi hypothetical protein 0.0072 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.1471 0.1471
Echinococcus granulosus 7TM GPCR rhodopsin 0.08 0.6889 0.6889
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0842 1
Echinococcus multilocularis musashi 0.0057 0.0369 0.0369
Brugia malayi G protein-coupled receptor 0.08 0.6889 0.6889
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0337 0.0337
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.0775 0.0775
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0198 0.0586
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0198 0.0278
Schistosoma mansoni opsin-like receptor 0.08 0.6889 0.6889
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Leishmania major mitochondrial DNA polymerase beta 0.0308 0.2566 0.7614
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0198 0.184
Loa Loa (eye worm) hypothetical protein 0.0242 0.199 0.199
Schistosoma mansoni hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0129 0.0383
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0332 0.0986
Loa Loa (eye worm) hypothetical protein 0.0056 0.036 0.036
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0052 0.0028
Echinococcus multilocularis G-protein coupled receptor, putative 0.08 0.6889 0.6889
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0332 0.0986
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Loa Loa (eye worm) doublecortin family protein 0.002 0.004 0.004
Mycobacterium tuberculosis Conserved protein 0.0035 0.017 0.0907
Echinococcus multilocularis neuropeptide Y receptor 0.08 0.6889 0.6889
Schistosoma mansoni neuropeptide receptor 0.08 0.6889 0.6889
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus granulosus tm gpcr rhodopsin 0.08 0.6889 0.6889
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.069 0.069
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0443 0.0443
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0006 0.0006
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0245 0.0726
Onchocerca volvulus 0.08 0.6889 1
Schistosoma mansoni biogenic amine receptor 0.08 0.6889 0.6889
Toxoplasma gondii hypothetical protein 0.0021 0.0049 0.0145
Brugia malayi intermediate filament protein 0.0057 0.0369 0.0369
Echinococcus multilocularis g protein coupled receptor 0.08 0.6889 0.6889
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0842 0.0842
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0053 0.0332 0.0489
Brugia malayi Adenylyl cyclase protein 0.0085 0.0615 0.0615
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0371 0.0371
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0129 0.0383
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0052
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.018 0.018
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0052 0.0052
Brugia malayi Doublecortin family protein 0.002 0.004 0.004
Brugia malayi putative neuropeptide receptor NPR1 0.08 0.6889 0.6889
Schistosoma mansoni rab6-interacting 0.002 0.004 0.004
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0053 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Brugia malayi Dopamine receptor protein 2 0.08 0.6889 0.6889
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.1471 0.1471
Echinococcus granulosus allatostatin A receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.004 0.004
Echinococcus granulosus adenylate cyclase 9 0.0085 0.0615 0.0615
Echinococcus multilocularis neuropeptides capa receptor 0.08 0.6889 0.6889
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.017 0.0236
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.08 0.6889 0.6889
Leishmania major DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0052 0.0254
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Onchocerca volvulus 0.08 0.6889 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Schistosoma mansoni fatty-acid amide hydrolase 0.0123 0.0946 0.0946
Echinococcus granulosus rhodopsin orphan GPCR 0.08 0.6889 0.6889
Brugia malayi hypothetical protein 0.018 0.1449 0.1449
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni amine GPCR 0.08 0.6889 0.6889
Schistosoma mansoni opsin-like receptor 0.08 0.6889 0.6889
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0399 0.3371 1
Plasmodium falciparum LCCL domain-containing protein 0.002 0.004 0.1199
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Brugia malayi phosphofructokinase 0.0111 0.0842 0.0842
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0052 0.0052
Echinococcus multilocularis neuropeptide receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0309 0.0309
Echinococcus granulosus biogenic amine 5HT receptor 0.08 0.6889 0.6889
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0198 0.0586
Onchocerca volvulus 0.0746 0.6412 0.9304
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0053 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.08 0.6889 0.6889
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0052 0.0052
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.1204 0.1204
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0198 0.0198
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0129 0.0171
Echinococcus granulosus neuropeptide receptor A26 0.08 0.6889 0.6889
Echinococcus granulosus fatty acid amide hydrolase 1 0.0123 0.0946 0.0946
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0129 0.0171
Loa Loa (eye worm) neuropeptide F receptor 0.08 0.6889 0.6889
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.017 0.0907
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.1471 0.1471
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.08 0.6889 0.6889
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0053 0.0332 0.0332
Echinococcus granulosus dna polymerase eta 0.0021 0.0052 0.0052
Onchocerca volvulus 0.08 0.6889 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0006 0.0006
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0053 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Mycobacterium tuberculosis Conserved protein 0.0035 0.017 0.0907
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0006 0.0019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Loa Loa (eye worm) beta-lactamase 0.0035 0.017 0.017
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Onchocerca volvulus 0.0082 0.0583 0.0793
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus granulosus Solute carrier family 22 5 0.1116 0.9662 0.9662
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0129 0.5
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0371 0.0371
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Brugia malayi larval opioid receptor 0.08 0.6889 0.6889
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.0775 0.0775
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.017 0.0907
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0021 0.0049 0.0235
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0074 0.0516 0.0516
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0309 0.0309
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0775 0.1181
Toxoplasma gondii ABC1 family protein 0.0035 0.017 0.0506
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0842 0.1286
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0053 0.0332 0.0332
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.08 0.6889 0.6889
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Schistosoma mansoni biogenic amine (5HT) receptor 0.08 0.6889 0.6889
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0332 0.0986
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.1143 0.3392
Brugia malayi GnHR receptor homolog 0.08 0.6889 0.6889
Brugia malayi AKH receptor 0.08 0.6889 0.6889
Schistosoma mansoni neuropeptide F-like receptor 0.08 0.6889 0.6889
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0053 0.0332 0.0332
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0074 0.0516 0.0516
Schistosoma mansoni neuropeptide f receptor 76f 0.08 0.6889 0.6889
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0053 0.0332 0.0332
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0259 0.0374
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.017 0.0907
Schistosoma mansoni hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0369 0.0369
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0052 0.0155
Brugia malayi neuropeptide F receptor 0.08 0.6889 0.6889
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0332 0.0986
Schistosoma mansoni peptide (allatostatin)-like receptor 0.08 0.6889 0.6889
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Echinococcus granulosus g protein coupled receptor 0.08 0.6889 0.6889
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Schistosoma mansoni hypothetical protein 0.0049 0.0298 0.0298
Plasmodium falciparum phosphodiesterase delta, putative 0.0053 0.0332 1
Onchocerca volvulus 0.08 0.6889 1
Trypanosoma brucei protein kinase, putative 0.0104 0.0775 0.2298
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0198 0.5
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.0775 0.0775
Brugia malayi ORL1-like opioid receptor 0.08 0.6889 0.6889
Echinococcus granulosus neuropeptide FF receptor 2 0.08 0.6889 0.6889
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0986
Schistosoma mansoni biogenic amine receptor 0.08 0.6889 0.6889
Schistosoma mansoni hypothetical protein 0.08 0.6889 0.6889
Echinococcus multilocularis neuropeptide s receptor 0.08 0.6889 0.6889
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0354 0.0354
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.1471 0.1471
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.08 0.6889 0.6889
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.017 0.0236
Brugia malayi Pre-SET motif family protein 0.0655 0.5617 0.5617
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0074 0.0516 0.0516
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0332 0.0986
Echinococcus granulosus tachykinin peptides receptor 99D 0.08 0.6889 0.6889
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.017 0.0907
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0006 0.0019
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0052 0.0254
Echinococcus granulosus dro:myosuppressin receptor 0.08 0.6889 0.6889
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.199 0.199
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.08 0.6889 0.6889
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.017 0.0506
Brugia malayi hypothetical protein 0.0125 0.0959 0.0959
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.017 0.0982
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0369 0.0369
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0842 0.0842
Leishmania major cAMP-specific phosphodiesterase, putative 0.0053 0.0332 0.0986
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0259 0.0768
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0527 0.0527
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0371 0.0371
Onchocerca volvulus 0.08 0.6889 1
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0111 0.0838 0.0838
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0006 0.0006
Echinococcus granulosus orexin receptor type 2 0.08 0.6889 0.6889
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0052 0.0155
Mycobacterium leprae conserved hypothetical protein 0.0035 0.017 0.1534
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Brugia malayi bHLH-PAS transcription factor 0.004 0.0214 0.0214
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Brugia malayi Serotonin/octopamine receptor family protein 7 0.08 0.6889 0.6889
Brugia malayi neuropeptide F receptor 0.08 0.6889 0.6889
Schistosoma mansoni biogenic amine receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) G-protein coupled receptor 0.08 0.6889 0.6889
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0371 0.0371
Brugia malayi jmjC domain containing protein 0.0058 0.0371 0.0371
Echinococcus granulosus lamin 0.0057 0.0369 0.0369
Onchocerca volvulus Neuropeptide F receptor homolog 0.08 0.6889 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0371 0.0371
Toxoplasma gondii GAF domain-containing protein 0.0021 0.0049 0.0145
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0052 0.0052
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.0775 0.2298
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0259 0.0768
Echinococcus granulosus dna polymerase kappa 0.0021 0.0052 0.0052
Onchocerca volvulus 0.08 0.6889 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.069 0.2047
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni single-minded 0.0054 0.0337 0.0337
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0499 0.0499
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.017 0.0236
Loa Loa (eye worm) hypothetical protein 0.0123 0.0946 0.0946
Toxoplasma gondii hypothetical protein 0.005 0.0301 0.0892
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.08 0.6889 0.6889
Brugia malayi G-protein coupled receptor 0.08 0.6889 0.6889
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.017 0.0506
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.0775 0.2298
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0163 0.0864
Echinococcus granulosus RUN 0.002 0.004 0.004
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.004 0.0118
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.017 0.0907
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0074 0.0516 0.0777
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.08 0.6889 0.6889
Schistosoma mansoni lipoxygenase 0.0056 0.0354 0.0354
Onchocerca volvulus 0.08 0.6889 1
Echinococcus granulosus g protein coupled receptor 0.08 0.6889 0.6889
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0986
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0129 0.0383
Onchocerca volvulus 0.004 0.0214 0.0255
Schistosoma mansoni inositol monophosphatase 0.0038 0.0198 0.0198
Onchocerca volvulus 0.08 0.6889 1
Brugia malayi hypothetical protein 0.0242 0.199 0.199
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0053 0.0332 0.0986
Brugia malayi amidase 0.0123 0.0946 0.0946
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0842 0.0842
Loa Loa (eye worm) hypothetical protein 0.0035 0.017 0.017
Brugia malayi follicle stimulating hormone receptor 0.1054 0.9122 0.9122
Schistosoma mansoni loxhd1 0.002 0.004 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.069 0.069
Plasmodium vivax phosphodiesterase gamma, putative 0.0053 0.0332 0.0986
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0053 0.0332 0.0489
Echinococcus granulosus peptide allatostatin:somatostatin 0.08 0.6889 0.6889
Onchocerca volvulus 0.08 0.6889 1
Echinococcus multilocularis sex peptide receptor 0.08 0.6889 0.6889
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.08 0.6889 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.017 0.017
Mycobacterium leprae Probable lipase LipE 0.0035 0.017 0.1534
Brugia malayi Inositol-1 0.0038 0.0198 0.0198
Schistosoma mansoni hypothetical protein 0.0187 0.151 0.151
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0354 0.0354
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0006 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni amine GPCR 0.08 0.6889 0.6889
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0129 0.0383
Echinococcus granulosus intermediate filament protein 0.0057 0.0369 0.0369
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.017 0.017
Leishmania major hypothetical protein, conserved 0.0053 0.0332 0.0986
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.017 0.017
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0129 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.0053 0.0332 0.0332
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0085 0.0615 0.084
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.08 0.6889 0.6889
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0198 0.0278
Loa Loa (eye worm) hypothetical protein 0.0057 0.0369 0.0369
Loa Loa (eye worm) acetyltransferase 0.0152 0.1204 0.1204
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0006 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.08 0.6889 0.6889
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0052 0.0155
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0214 0.0214
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0129 0.0171
Echinococcus granulosus neuropeptides capa receptor 0.08 0.6889 0.6889
Echinococcus multilocularis alpha 1A adrenergic receptor 0.08 0.6889 0.6889
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.017 0.017
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) G-protein coupled receptor 0.08 0.6889 0.6889
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.08 0.6889 0.6889
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.08 0.6889 0.6889
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.1154 1 1
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0399 0.3371 0.3371
Echinococcus multilocularis dna polymerase eta 0.0021 0.0052 0.0052
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0198 0.0278
Brugia malayi Dopamine receptor protein 1 0.08 0.6889 0.6889
Brugia malayi Serotonin receptor 0.08 0.6889 0.6889
Schistosoma mansoni neuropeptide receptor 0.08 0.6889 0.6889
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0308 0.2566 0.7614
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0399 0.3371 1
Loa Loa (eye worm) hypothetical protein 0.018 0.1449 0.1449
Brugia malayi RE15519p 0.08 0.6889 0.6889
Echinococcus granulosus fatty acid amide hydrolase 1 0.0123 0.0946 0.0946
Schistosoma mansoni hypothetical protein 0.002 0.004 0.004
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0842 0.64
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Echinococcus granulosus rhodopsin orphan GPCR 0.08 0.6889 0.6889
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0775 0.2298
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0226 0.2403
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.08 0.6889 0.6889
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.066 0.066
Giardia lamblia Hypothetical protein 0.0053 0.0332 0.3875
Brugia malayi PAS domain containing protein 0.0054 0.0337 0.0337
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0053 0.0332 0.0332
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0443 0.1316
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0006 0.0019
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0371 0.0371
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0111 0.0838 0.1281
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0443 0.1316
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.0775 1
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0443 0.0443
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0443 0.0443
Brugia malayi hypothetical protein 0.002 0.004 0.004
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0443 0.2415
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0129 0.0171
Echinococcus multilocularis g-protein coupled receptor 0.08 0.6889 0.6889
Echinococcus granulosus fmrfamide receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0842 0.2498
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.009 0.0655 0.1942
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0006 0.0191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0021 0.0049 0.0235
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Schistosoma mansoni lamin 0.0057 0.0369 0.0369
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0052 0.0052
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0328 0.0973
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0245 0.0726
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Mycobacterium ulcerans beta-lactamase 0.0035 0.017 0.0982
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0399 0.3371 1
Schistosoma mansoni hypothetical protein 0.08 0.6889 0.6889
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0006 0.0019
Entamoeba histolytica hypothetical protein 0.0072 0.0499 0.5659
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0053 0.0332 0.3875
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0053 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0085 0.0615 0.0615
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0129 0.0171
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.1471 0.1471
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0842 0.4616
Onchocerca volvulus 0.08 0.6889 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.004 0.004
Plasmodium falciparum phosphodiesterase gamma, putative 0.0053 0.0332 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0259 0.0768
Brugia malayi 6-phosphofructokinase 0.0111 0.0842 0.0842
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.08 0.6889 0.6889
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0842 0.1286
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0527 0.0527
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0006 0.0006
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0053 0.0332 0.0986
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.0775 0.0775
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0129 0.106
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0226 0.2198
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0332 0.0489
Mycobacterium ulcerans hypothetical protein 0.0162 0.1288 1
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Echinococcus multilocularis GPCR, family 2 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0842 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.1204 0.1204
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.017 0.0982
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0842 1
Echinococcus granulosus neuropeptides capa receptor 0.08 0.6889 0.6889
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0052 0.0155
Echinococcus multilocularis somatostatin receptor 0.08 0.6889 0.6889
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0245 0.0726
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0443 0.0443
Echinococcus multilocularis rhodopsin orphan GPCR 0.08 0.6889 0.6889
Echinococcus granulosus tm gpcr rhodopsin 0.08 0.6889 0.6889
Echinococcus multilocularis neuropeptides capa receptor 0.08 0.6889 0.6889
Mycobacterium ulcerans putative regulatory protein 0.004 0.0214 0.1337
Loa Loa (eye worm) hypothetical protein 0.0053 0.0332 0.0332
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0053 0.0332 0.0986
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.0035 0.017 0.017
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.08 0.6889 0.6889
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0074 0.0516 0.0516
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0053 0.0332 1
Schistosoma mansoni myosin xvIII 0.08 0.6889 0.6889
Entamoeba histolytica hypothetical protein 0.0072 0.0499 0.5659
Loa Loa (eye worm) TYRA-2 protein 0.08 0.6889 0.6889
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0049 0.0046
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0052 0.0028
Schistosoma mansoni growth hormone secretagogue receptor 0.08 0.6889 0.6889
Echinococcus multilocularis serotonin receptor 0.08 0.6889 0.6889
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0399 0.3371 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0129 0.388
Schistosoma mansoni adenoreceptor 0.08 0.6889 0.6889
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.004
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0129 0.0171
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0074 0.0516 0.0516
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.08 0.6889 0.6889
Schistosoma mansoni survival motor neuron protein 0.0049 0.0298 0.0298
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0129 0.097
Onchocerca volvulus 0.08 0.6889 1
Mycobacterium ulcerans lipase LipD 0.0035 0.017 0.0982
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0655 0.5617 0.5617
Echinococcus multilocularis neuropeptide receptor 0.08 0.6889 0.6889
Brugia malayi 6-phosphofructokinase 0.0111 0.0842 0.0842
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0169 0.0169
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.08 0.6889 0.6889
Brugia malayi MAP kinase sur-1 0.0104 0.0775 0.0775
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.017 0.0907
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0499 0.0499
Brugia malayi Melatonin receptor type 1A 0.08 0.6889 0.6889
Schistosoma mansoni amine GPCR 0.08 0.6889 0.6889
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.004 0.004
Schistosoma mansoni microtubule-associated protein tau 0.0726 0.6239 0.6239
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0053 0.0332 0.0332
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.08 0.6889 0.6889
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.1166 0.1166
Schistosoma mansoni hypothetical protein 0.0072 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0443 0.3185
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0123 0.0946 0.0946
Giardia lamblia hypothetical protein 0.0053 0.0332 0.3875
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Brugia malayi sulfakinin receptor protein 0.08 0.6889 0.6889
Echinococcus granulosus geminin 0.0187 0.151 0.151
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0183 0.1471 0.1471
Brugia malayi jmjC domain containing protein 0.0058 0.0371 0.0371
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.1471 0.1471
Brugia malayi Tachykinin-like peptides receptor 99D 0.08 0.6889 0.6889
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.0775 0.0775
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0108 0.0108
Echinococcus granulosus neuropeptide Y receptor 0.08 0.6889 0.6889
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0053 0.0332 0.0332
Echinococcus granulosus neuropeptide receptor 0.08 0.6889 0.6889
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0006 0.0006
Echinococcus granulosus g-protein coupled receptor 0.08 0.6889 0.6889
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.08 0.6889 0.6889
Echinococcus granulosus G protein coupled receptor 139 0.08 0.6889 0.6889
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.0775 0.2298
Schistosoma mansoni DNA polymerase eta 0.0021 0.0052 0.0052
Mycobacterium ulcerans hypothetical protein 0.0035 0.017 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0371 0.055
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0399 0.3371 0.3371
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0163 0.1437
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.017 0.0236
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0371 0.0371
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.0775 0.2298
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.08 0.6889 0.6889
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0516 0.0777
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0111 0.0838 0.2487
Echinococcus multilocularis adenylate cyclase 9 0.0085 0.0615 0.0615
Loa Loa (eye worm) hypothetical protein 0.0051 0.0309 0.0309
Onchocerca volvulus 0.08 0.6889 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0443 0.3185
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0123 0.0946 0.0946
Echinococcus multilocularis tachykinin peptides receptor 99D 0.08 0.6889 0.6889
Schistosoma mansoni opsin-like receptor 0.08 0.6889 0.6889
Onchocerca volvulus 0.0085 0.0615 0.084
Onchocerca volvulus 0.08 0.6889 1
Trypanosoma brucei unspecified product 0.0021 0.0052 0.0155
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.1471 0.1471
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0332 0.0489
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.017 0.017
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0053 0.0332 0.0332
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0049 0.0145
Brugia malayi beta-lactamase 0.0035 0.017 0.017
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0332 0.0986
Brugia malayi hypoxia-induced factor 1 0.0166 0.1326 0.1326
Brugia malayi hypothetical protein 0.08 0.6889 0.6889
Echinococcus multilocularis orexin receptor type 2 0.08 0.6889 0.6889
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.069 0.069
Echinococcus multilocularis adenylate cyclase type IX 0.012 0.0919 0.0919
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0775 0.1181
Echinococcus multilocularis microtubule associated protein 2 0.0726 0.6239 0.6239
Echinococcus granulosus biogenic amine 5HT receptor 0.08 0.6889 0.6889
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0111 0.0838 0.0838
Echinococcus multilocularis g protein coupled receptor 0.08 0.6889 0.6889
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0111 0.0838 0.1281
Leishmania major hypothetical protein, conserved 0.0053 0.0332 0.0986
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0489
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.08 0.6889 0.6889
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.08 0.6889 0.6889
Plasmodium falciparum GAF domain-related protein, putative 0.0021 0.0049 0.147
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0049
Echinococcus granulosus thyrotropin releasing hormone receptor 0.08 0.6889 0.6889
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0371 0.055
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0129 0.0383
Loa Loa (eye worm) hypothetical protein 0.08 0.6889 0.6889
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.069 0.069
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.08 0.6889 0.6889
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0129 0.388
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0006 0.0006
Loa Loa (eye worm) adenylyl cyclase 3 0.0202 0.1637 0.1637
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0074 0.0516 0.0516
Schistosoma mansoni biogenic amine (dopamine) receptor 0.08 0.6889 0.6889
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0332 0.0986
Onchocerca volvulus 0.08 0.6889 1
Onchocerca volvulus 0.0049 0.0298 0.0378
Schistosoma mansoni inositol monophosphatase 0.0038 0.0198 0.0198
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0842 0.0842
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0052 0.0052
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.009 0.0655 0.0993
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.08 0.6889 0.6889
Onchocerca volvulus 0.0035 0.017 0.0191
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0135 0.0135
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0006 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0775 0.0775
Echinococcus granulosus 7tm_1 domain containing protein 0.08 0.6889 0.6889
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.08 0.6889 0.6889
Echinococcus granulosus neuropeptide s receptor 0.08 0.6889 0.6889
Plasmodium vivax SET domain protein, putative 0.0094 0.069 0.2047
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0028 0.0108 0.0108
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0111 0.0838 0.0838
Onchocerca volvulus 0.0035 0.017 0.0191
Loa Loa (eye worm) hypothetical protein 0.0035 0.017 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0052 0.0155
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0111 0.0838 0.2487
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.0775 0.2298
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.1143 0.3392
Brugia malayi Cytochrome P450 family protein 0.0036 0.018 0.018
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0775 0.2298
Schistosoma mansoni polycystin 1-related 0.002 0.004 0.004
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0006 0.0006

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 10.6 uM Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli ChEMBL. 15771430
Ki (binding) = 10.6 uM Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli ChEMBL. 15771430

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.