Detailed information for compound 312828

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 636.772 | Formula: C37H48O9
  • H donors: 0 H acceptors: 0 LogP: 7.93 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCOC(c1ccc2c(c1)OCO2)C(Oc1ccc(cc1OC)[C@H]1O[C@H]([C@H]([C@H]1C)C)c1ccc(c(c1)OC)OC)OC
  • InChi: 1S/C37H48O9/c1-8-9-10-11-18-42-36(27-13-16-29-33(21-27)44-22-43-29)37(41-7)45-30-17-14-26(20-32(30)40-6)35-24(3)23(2)34(46-35)25-12-15-28(38-4)31(19-25)39-5/h12-17,19-21,23-24,34-37H,8-11,18,22H2,1-7H3/t23-,24+,34+,35-,36?,37?/m0/s1
  • InChiKey: PDFCOXIQWAJVFD-IIOXYAKOSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0016 0.0024
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0337 0.071
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0091 0.0653
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Brugia malayi DNA polymerase family B containing protein 0.0019 0.0091 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Onchocerca volvulus 0.0061 0.0565 0.1606
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0039 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Onchocerca volvulus 0.0061 0.0565 0.1606
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0016 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Loa Loa (eye worm) hypothetical protein 0.0472 0.513 1
Echinococcus granulosus tm gpcr rhodopsin 0.0908 0.9986 1
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0019 0.0091 0.0075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Loa Loa (eye worm) hypothetical protein 0.0168 0.1746 0.3384
Schistosoma mansoni biogenic amine receptor 0.0035 0.0273 0.0544
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.017 0.0155
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Trypanosoma cruzi hexose transporter, putative 0.0135 0.1389 1
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0273 0.0258
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0715 0.515
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0019 0.0091 0.0075
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0273 0.0503
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0035 0.0273 0.0258
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0414 0.0842
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0016 0.0107
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0014 0.0039 0.0046
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0611 0.0598
Brugia malayi Dopamine receptor protein 2 0.0035 0.0273 0.0544
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0019 0.0091 0.0653
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0273 0.0258
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0035 0.0273 0.0544
Onchocerca volvulus 0.0035 0.0273 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.1389 0.2929
Onchocerca volvulus 0.0061 0.0565 0.1606
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Trichomonas vaginalis myo-inositol transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0273 0.0258
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0066 0.0612 0.0925
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0035 0.0273 0.0258
Echinococcus multilocularis GPCR, family 2 0.0016 0.0056 0.0041
Loa Loa (eye worm) hypothetical protein 0.0064 0.0597 0.1136
Trypanosoma cruzi hexose transporter 0.0135 0.1389 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.028 0.056
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0273 0.0258
Echinococcus multilocularis allatostatin A receptor 0.0035 0.0273 0.0258
Leishmania major glucose transporter, lmgt1 0.0135 0.1389 1
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0273 0.0503
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0039 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Leishmania major DNA polymerase eta, putative 0.0014 0.0042 0.0302
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0014 0.0039 0.0024
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0064 0.0597 0.0583
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0115 0.0828
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.017 0.0415
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0016 0.0107
Schistosoma mansoni hypothetical protein 0.0016 0.0056 0.0086
Brugia malayi putative neuropeptide receptor 0.0035 0.0273 0.0544
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.3121 0.835
Loa Loa (eye worm) hypothetical protein 0.0472 0.513 1
Brugia malayi follicle stimulating hormone receptor 0.0035 0.0273 0.0544
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Loa Loa (eye worm) LGC-31 protein 0.0014 0.0039 0.0046
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0333 0.2278
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0273 0.0258
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0035 0.0273 0.0258
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0019 0.0091 0.0075
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0042 0.0302
Schistosoma mansoni blooms syndrome DNA helicase 0.0045 0.0386 0.0784
Schistosoma mansoni alpha-1 adrenergic receptor 0.0035 0.0273 0.0544
Brugia malayi major facilitator superfamily protein 0.0061 0.0565 0.1162
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0035 0.0273 0.0258
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0414 0.0842
Entamoeba histolytica hypothetical protein 0.0048 0.0414 0.107
Brugia malayi Cation transporter family protein 0.0014 0.0039 0.005
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0066 0.0612 0.0597
Brugia malayi Telomerase reverse transcriptase 0.0224 0.2376 0.4994
Giardia lamblia Prolyl-tRNA synthetase 0.0064 0.0597 0.1563
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.008
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0259 0.0515
Echinococcus granulosus solute carrier family 22 0.0061 0.0565 0.0551
Onchocerca volvulus 0.0061 0.0565 0.1606
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Plasmodium falciparum mitogen-activated protein kinase 2 0.0346 0.3734 0.3724
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0611 0.0598
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.004 0.0325 0.0491
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0437 0.4742 0.474
Trichomonas vaginalis glucose transporter, putative 0.0135 0.1389 0.2929
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.037 0.2661
Leishmania major glucose transporter, lmgt2 0.0135 0.1389 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0273 0.0544
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0098 0.0978 0.2587
Mycobacterium ulcerans hypothetical protein 0.0036 0.028 0.1916
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0019 0.0091 0.0653
Brugia malayi larval opioid receptor 0.0035 0.0273 0.0544
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0014 0.0039 0.005
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0042 0.0056
Giardia lamblia Telomerase catalytic subunit 0.0084 0.0819 0.216
Echinococcus granulosus orexin receptor type 2 0.0035 0.0273 0.0258
Brugia malayi Flap endonuclease-1 0.0026 0.017 0.0327
Echinococcus granulosus somatostatin receptor 0.0035 0.0273 0.0258
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0066 0.0612 0.0597
Onchocerca volvulus 0.0035 0.0273 0.0714
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0346 0.3734 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0039 0.0024
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.1464 0.6022
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0414 0.2826
Onchocerca volvulus 0.0035 0.0273 0.0714
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0414 0.0399
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0066 0.0612 0.0925
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Brugia malayi excitatory GABA receptor EXP-1A 0.0014 0.0039 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0611 0.0598
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0099 0.015
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0019 0.0091 0.0075
Schistosoma mansoni nAChR subunit 0.0014 0.0039 0.005
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0273 0.0258
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0308 0.3313 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.037 0.0779
Schistosoma mansoni sugar transporter 0.0061 0.0565 0.1162
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.3121 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Schistosoma mansoni hypothetical protein 0.0016 0.0056 0.0086
Entamoeba histolytica protein kinase, putative 0.0066 0.0611 0.1602
Trichomonas vaginalis sugar transporter, putative 0.0135 0.1389 0.2929
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Brugia malayi G-protein coupled receptor 0.0035 0.0273 0.0544
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0064 0.0597 0.1258
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0064 0.0597 0.1563
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Trichomonas vaginalis sugar transport protein, putative 0.0061 0.0565 0.1191
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Toxoplasma gondii facilitative glucose transporter GT1 0.0437 0.4742 0.7166
Brugia malayi AKH receptor 0.0035 0.0273 0.0544
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0038 0.0309 0.0294
Echinococcus granulosus geminin 0.0169 0.1759 0.1749
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Echinococcus multilocularis flap endonuclease 1 0.0026 0.017 0.0155
Onchocerca volvulus 0.0035 0.0273 0.0714
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis serotonin receptor 0.0168 0.1746 0.1735
Echinococcus granulosus solute carrier family 22 0.0061 0.0565 0.0551
Schistosoma mansoni nAChR subunit 0.0014 0.0039 0.005
Trypanosoma cruzi glucose transporter, putative 0.0061 0.0565 0.4067
Brugia malayi putative neuropeptide receptor NPR1 0.0035 0.0273 0.0544
Schistosoma mansoni hypothetical protein 0.0016 0.0056 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0273 0.0258
Brugia malayi sulfakinin receptor protein 0.0035 0.0273 0.0544
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0035 0.0273 0.0258
Mycobacterium ulcerans integral membrane transport protein 0.0061 0.0565 0.3859
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0061 0.0565 0.4067
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Schistosoma mansoni hypothetical protein 0.0169 0.1759 0.369
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0134 0.2978
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0065 0.047
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0039 0.0024
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0039 0.005
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0014 0.0039 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0065 0.047
Brugia malayi Dopamine receptor 0.0035 0.0273 0.0544
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0038 0.0309 0.0294
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0273 0.0544
Onchocerca volvulus 0.0035 0.0273 0.0714
Schistosoma mansoni neuropeptide receptor 0.0035 0.0273 0.0544
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0414 0.0625
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0014 0.0039 0.005
Schistosoma mansoni adenoreceptor 0.0035 0.0273 0.0544
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0414 0.2978
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0019 0.0091 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0565 0.1191
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0019 0.0091 0.0202
Schistosoma mansoni nAChR subunit 0.0014 0.0039 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0035 0.0273 0.0258
Trichomonas vaginalis esterase, putative 0.0036 0.028 0.0592
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0042 0.0056
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0715 0.515
Onchocerca volvulus 0.0035 0.0273 0.0714
Brugia malayi major facilitator superfamily protein 0.0061 0.0565 0.1162
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0039 0.0024
Schistosoma mansoni nAChR subunit 0.0014 0.0039 0.005
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0019 0.0091 0.0653
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Echinococcus multilocularis synaptic vesicle 2 protein 0.0061 0.0565 0.0551
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0035 0.0273 0.0258
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0597 0.123
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Giardia lamblia DINP protein human, muc B family 0.0021 0.0115 0.0267
Plasmodium vivax hexose transporter 0.0437 0.4742 0.4733
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0273 0.0258
Trypanosoma brucei THT1 - hexose transporter, putative 0.0135 0.1389 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0042 0.0051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.028 0.1154
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0434 0.0885
Trichomonas vaginalis sugar transporter, putative 0.0135 0.1389 0.2929
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0565 0.1191
Loa Loa (eye worm) RecQ helicase 0.0065 0.0604 0.115
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0414 0.0842
Echinococcus granulosus Sugar transporter ERD6 protein 0.0061 0.0565 0.0551
Echinococcus granulosus calcium dependent protein kinase 0.0062 0.0566 0.0552
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0273 0.0258
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0014 0.0039 0.0024
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0035 0.0273 0.0544
Onchocerca volvulus 0.0061 0.0565 0.1606
Toxoplasma gondii RNA-directed DNA polymerase 0.0084 0.0819 0.1237
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Chlamydia trachomatis lysine--tRNA ligase 0.0048 0.0414 1
Echinococcus multilocularis bloom syndrome protein 0.0065 0.0604 0.059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0014 0.0039 0.005
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0039 0.0024
Schistosoma mansoni glucose transport protein 0.0437 0.4742 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0061 0.0565 0.0551
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Giardia lamblia DNA repair protein RAD52 0.0346 0.3734 1
Trichomonas vaginalis sugar transporter, putative 0.0135 0.1389 0.2929
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0065 0.047
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0056 0.0086
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Schistosoma mansoni nAChR subunit 0.0014 0.0039 0.005
Plasmodium vivax sugar transporter, putative 0.0061 0.0565 0.055
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0611 0.1165
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0019 0.0091 0.0159
Plasmodium falciparum hexose transporter 0.0437 0.4742 0.4733
Mycobacterium ulcerans beta-lactamase 0.0036 0.028 0.1916
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Loa Loa (eye worm) melatonin receptor type 1A 0.0035 0.0273 0.0503
Trichomonas vaginalis DNA helicase recq, putative 0.0065 0.0604 0.1273
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0273 0.0258
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0019 0.0091 0.0075
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0273 0.0544
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0014 0.0039 0.0024
Plasmodium vivax calcium-dependent protein kinase, putative 0.0066 0.0612 0.0597
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0019 0.0091 0.0653
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0061 0.0565 0.3859
Brugia malayi Major Facilitator Superfamily protein 0.0061 0.0565 0.1162
Schistosoma mansoni opsin-like receptor 0.0035 0.0273 0.0544
Echinococcus granulosus fmrfamide receptor 0.0035 0.0273 0.0258
Brugia malayi RE15519p 0.0035 0.0273 0.0544
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0039 0.0024
Echinococcus multilocularis G-protein coupled receptor, putative 0.0035 0.0273 0.0258
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0414 0.2826
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0051
Onchocerca volvulus 0.0035 0.0273 0.0714
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0019 0.0091 0.0653
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0035 0.0273 0.0544
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0273 0.0544
Echinococcus multilocularis g-protein coupled receptor 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.002 0.0099 0.0163
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0019 0.0091 0.0147
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0337 0.2299
Echinococcus granulosus flap endonuclease 1 0.0026 0.017 0.0155
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0908 0.9986 1
Brugia malayi Cation transporter family protein 0.0014 0.0039 0.005
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.017 0.0302
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0019 0.0091 0.0075
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0273 0.0258
Onchocerca volvulus 0.0035 0.0273 0.0714
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.3121 0.835
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Onchocerca volvulus 0.0035 0.0273 0.0714
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.017 0.0257
Loa Loa (eye worm) major facilitator superfamily transporter 0.0061 0.0565 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0565 0.1191
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Schistosoma mansoni amine GPCR 0.0035 0.0273 0.0544
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Echinococcus multilocularis dro:myosuppressin receptor 0.0035 0.0273 0.0258
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0035 0.0273 0.0544
Schistosoma mansoni amine GPCR 0.0035 0.0273 0.0544
Schistosoma mansoni glucose transport protein 0.0437 0.4742 1
Trypanosoma cruzi sugar transporter, putative 0.0061 0.0565 0.4067
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0014 0.0039 0.005
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0611 0.4403
Echinococcus granulosus dna polymerase kappa 0.0041 0.0337 0.0322
Trypanosoma brucei THT1 - hexose transporter, putative 0.0135 0.1389 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Echinococcus granulosus 7TM GPCR rhodopsin 0.0035 0.0273 0.0258
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0107 0.1072 0.2065
Loa Loa (eye worm) hypothetical protein 0.0036 0.028 0.0518
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0035 0.0273 0.0544
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0091 0.0202
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0273 0.0503
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0056 0.008
Toxoplasma gondii transporter, major facilitator family protein 0.0061 0.0565 0.0854
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0039 0.0024
Onchocerca volvulus 0.0035 0.0273 0.0714
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Schistosoma mansoni hypothetical protein 0.0016 0.0056 0.0086
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0273 0.0258
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.3121 0.835
Brugia malayi hypothetical protein 0.0061 0.0565 0.1162
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0019 0.0091 0.0157
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0011 0.0004 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0611 0.129
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0056 0.0041
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0038 0.0309 0.0573
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0611 0.1261
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0039 0.0046
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0112
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0042 0.0348 0.0734
Schistosoma mansoni nAChR subunit 0.0014 0.0039 0.005
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0273 0.0258
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0084 0.0819 0.5896
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0019 0.0091 0.0157
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0019 0.0091 0.0159
Echinococcus granulosus serotonin receptor 0.0035 0.0273 0.0258
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0273 0.0258
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0112
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Echinococcus multilocularis G protein coupled receptor 139 0.0035 0.0273 0.0258
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.028 0.202
Onchocerca volvulus 0.0061 0.0565 0.1606
Trypanosoma brucei sugar transporter, putative 0.0061 0.0565 0.4067
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0019 0.0091 0.0075
Loa Loa (eye worm) hypothetical protein 0.0034 0.0259 0.0476
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.028 0.1154
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0226 0.1627
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0437 0.4742 0.474
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0134 0.0916
Echinococcus granulosus biogenic amine 5HT receptor 0.0168 0.1746 0.1735
Mycobacterium leprae Probable lipase LipE 0.0036 0.028 0.1916
Schistosoma mansoni biogenic amine receptor 0.0035 0.0273 0.0544
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0014 0.0039 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus granulosus General substrate transporter 0.0375 0.4058 0.4055
Onchocerca volvulus 0.0061 0.0565 0.1606
Echinococcus multilocularis neuropeptide FF receptor 2 0.0035 0.0273 0.0258
Brugia malayi neuropeptide F receptor 0.0035 0.0273 0.0544
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0273 0.0258
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0112
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0414 0.107
Toxoplasma gondii DNA polymerase 0.0019 0.0091 0.0137
Schistosoma mansoni amine GPCR 0.0035 0.0273 0.0544
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0014 0.0039 0.005
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0014 0.0039 0.0046
Echinococcus multilocularis transcription factor eb 0.0107 0.1078 0.1065
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Echinococcus multilocularis serotonin receptor 0.0168 0.1746 0.1735
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.028 0.1154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.028 0.056
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0042 0.0026
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0014 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0064 0.0597 0.1136
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0414 0.2978
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0414 0.0399
Loa Loa (eye worm) hypothetical protein 0.0038 0.0309 0.0573
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0035 0.0273 0.0544
Toxoplasma gondii protein kinase, putative 0.0605 0.6617 1
Trichomonas vaginalis glucose transporter, putative 0.0061 0.0565 0.1191
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0115 0.0828
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0273 0.0503
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0064 0.0597 0.0583
Schistosoma mansoni neuropeptide f receptor 76f 0.0035 0.0273 0.0544
Echinococcus multilocularis solute carrier family 22 0.0061 0.0565 0.0551
Brugia malayi beta-lactamase family protein 0.0036 0.028 0.056
Brugia malayi DNA polymerase alpha catalytic subunit 0.0019 0.0091 0.0159
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0016 0.0024
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0309 0.062
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0039 0.005
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0333 0.1372
Echinococcus multilocularis General substrate transporter 0.0375 0.4058 0.4055
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0091 0.0653
Plasmodium falciparum calcium-dependent protein kinase 3 0.0066 0.0612 0.0597
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0014 0.0039 0.005
Leishmania major myo-inositol/proton symporter (MIT) 0.0061 0.0565 0.4067
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0014 0.0039 0.0046
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0273 0.0258
Schistosoma mansoni amine GPCR 0.0395 0.428 0.9022
Schistosoma mansoni glucose transporter 0.0061 0.0565 0.1162
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0107 0.1078 0.2247
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0147
Trypanosoma brucei glucose transporter 2A 0.0135 0.1389 1
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0016 0.0107
Echinococcus granulosus G protein coupled receptor 139 0.0035 0.0273 0.0258
Toxoplasma gondii ABC1 family protein 0.0036 0.028 0.0424
Brugia malayi Dopamine receptor protein 1 0.0035 0.0273 0.0544
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0715 0.515
Leishmania major glucose transporter, lmgt3 0.0135 0.1389 1
Schistosoma mansoni biogenic amine receptor 0.0035 0.0273 0.0544
Brugia malayi Tachykinin-like peptides receptor 99D 0.0035 0.0273 0.0544
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Echinococcus multilocularis sex peptide receptor 0.0035 0.0273 0.0258
Mycobacterium tuberculosis Conserved protein 0.0036 0.028 0.1154
Onchocerca volvulus 0.0061 0.0565 0.1606
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Entamoeba histolytica protein kinase, putative 0.0066 0.0611 0.1602
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0019 0.0091 0.0075
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Plasmodium falciparum proline--tRNA ligase 0.0075 0.0715 0.0701
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Trypanosoma brucei unspecified product 0.0034 0.0263 0.1897
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.028 0.1916
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0061 0.0565 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0042 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0038 0.0309 0.0293
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0337 0.2424
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0337 0.071
Schistosoma mansoni sugar transporter 0.0061 0.0565 0.1162
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0705 0.5079
Schistosoma mansoni biogenic amine (5HT) receptor 0.0168 0.1746 0.3661
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0019 0.0091 0.0075
Brugia malayi Sugar transporter family protein 0.0061 0.0565 0.1162
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0061 0.0565 0.2324
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0035 0.0273 0.0544
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0039 0.005
Echinococcus multilocularis geminin 0.0169 0.1759 0.1749
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0039 0.005
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0041 0.0333 0.0318
Brugia malayi Sugar transporter family protein 0.0437 0.4742 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0437 0.4742 0.474
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0414 0.2826
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0414 0.0872
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0039 0.005
Echinococcus multilocularis solute carrier family 22 0.0061 0.0565 0.0551
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0014 0.0039 0.0046
Onchocerca volvulus 0.0035 0.0273 0.0714
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0337 0.0322
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0039 0.005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0035 0.0273 0.0714
Loa Loa (eye worm) hypothetical protein 0.0036 0.028 0.0518
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Echinococcus granulosus neuropeptide receptor 0.0035 0.0273 0.0258
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0019 0.0091 0.0137
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0019 0.0091 0.0191
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0337 0.2424
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0437 0.4742 0.474
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus multilocularis solute carrier family 22 0.0061 0.0565 0.0551
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Schistosoma mansoni opsin-like receptor 0.0035 0.0273 0.0544
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0038 0.0309 0.0294
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0346 0.3734 0.3724
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus granulosus sex peptide receptor 0.0035 0.0273 0.0258
Schistosoma mansoni sugar transporter 0.0061 0.0565 0.1162
Leishmania major DNA polymerase kappa, putative 0.0021 0.0115 0.0828
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0437 0.4742 0.474
Loa Loa (eye worm) hypothetical protein 0.0066 0.0611 0.1165
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0042 0.0056
Loa Loa (eye worm) hypothetical protein 0.0036 0.028 0.0518
Mycobacterium tuberculosis Conserved protein 0.0036 0.028 0.1154
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.1464 1
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0042 0.0302
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0035 0.0273 0.0503
Onchocerca volvulus 0.0035 0.0273 0.0714
Trypanosoma brucei telomerase reverse transcriptase 0.0084 0.0819 0.5896
Loa Loa (eye worm) hypothetical protein 0.0036 0.028 0.0518
Echinococcus granulosus solute carrier family 22 0.0061 0.0565 0.0551
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.028 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.1389 0.2929
Loa Loa (eye worm) sugar transporter 0.0437 0.4742 0.9241
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.037 0.2661
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.017 0.1225
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0175 0.0312
Brugia malayi Major Facilitator Superfamily protein 0.0061 0.0565 0.1162
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.028 0.0592
Echinococcus granulosus g-protein coupled receptor 0.0035 0.0273 0.0258
Trichomonas vaginalis DNA helicase recq1, putative 0.0065 0.0604 0.1273
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus granulosus neuropeptide FF receptor 2 0.0035 0.0273 0.0258
Schistosoma mansoni protein kinase 0.0066 0.0611 0.1261
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.028 0.0266
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0061 0.0565 0.3859
Schistosoma mansoni hypothetical protein 0.0035 0.0273 0.0544
Echinococcus granulosus dna polymerase eta 0.0014 0.0042 0.0026
Toxoplasma gondii sugar transporter ST3 0.0061 0.0565 0.0854
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0014 0.0039 0.0024
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0039 0.0024
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0084 0.0819 0.5896
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0014 0.0039 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Schistosoma mansoni hypothetical protein 0.0437 0.4742 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0226 0.1627
Toxoplasma gondii sugar transporter ST2 0.0061 0.0565 0.0854
Trichomonas vaginalis conserved hypothetical protein 0.0437 0.4742 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0035 0.0273 0.0258
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0715 0.515
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0091 0.0653
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0066 0.0612 0.0925
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.028 0.202
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.028 0.1154
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0056 0.0041
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Brugia malayi hypothetical protein 0.0061 0.0565 0.1162
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0042 0.0056
Echinococcus multilocularis neuropeptide s receptor 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Giardia lamblia Sgs1 DNA helicase, putative 0.0038 0.0309 0.0788
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.028 0.0592
Schistosoma mansoni myosin xvIII 0.0035 0.0273 0.0544
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Onchocerca volvulus 0.0036 0.028 0.0737
Plasmodium vivax hypothetical protein, conserved 0.0036 0.028 0.0265
Trypanosoma brucei glucose transporter 1E 0.0135 0.1389 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0039 0.005
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0715 0.515
Loa Loa (eye worm) TYRA-2 protein 0.0035 0.0273 0.0503
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0273 0.0544
Plasmodium vivax telomerase reverse transcriptase, putative 0.0084 0.0819 0.0804
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0035 0.0273 0.0503
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0014 0.0039 0.0024
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0039 0.0024
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.028 0.202
Loa Loa (eye worm) major facilitator superfamily transporter 0.0061 0.0565 0.1074
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0061 0.0565 0.055
Schistosoma mansoni neuropeptide receptor 0.0035 0.0273 0.0544
Echinococcus multilocularis neuropeptide receptor A26 0.0035 0.0273 0.0258
Echinococcus granulosus 7tm_1 domain containing protein 0.0035 0.0273 0.0258
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0035 0.0273 0.0258
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Schistosoma mansoni protein kinase 0.0066 0.0611 0.1261
Toxoplasma gondii sugar transporter ST1 0.0061 0.0565 0.0854
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0134 0.0382
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0273 0.0258
Brugia malayi Serotonin receptor 0.0035 0.0273 0.0544
Mycobacterium tuberculosis Conserved protein 0.0036 0.028 0.1154
Brugia malayi G-protein coupled receptor 0.0035 0.0273 0.0544
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0056 0.0086
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0014 0.0039 0.005
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.1464 1
Echinococcus multilocularis solute carrier family 22 0.0061 0.0565 0.0551
Onchocerca volvulus 0.0061 0.0565 0.1606
Onchocerca volvulus DNA polymerase homolog 0.0019 0.0091 0.0157
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0611 0.0598
Echinococcus granulosus bloom syndrome protein 0.0065 0.0604 0.059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Onchocerca volvulus 0.0061 0.0565 0.1606
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0019 0.0091 0.0653
Loa Loa (eye worm) hypothetical protein 0.0168 0.1746 0.3384
Plasmodium vivax proline--tRNA ligase, putative 0.0075 0.0715 0.0701
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0414 0.0399
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Schistosoma mansoni neuropeptide receptor 0.0035 0.0273 0.0544
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0019 0.0091 0.0191
Brugia malayi Melatonin receptor type 1A 0.0035 0.0273 0.0544
Brugia malayi Serotonin receptor 0.0035 0.0273 0.0544
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.028 0.1154
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Schistosoma mansoni sugar transporter 0.0061 0.0565 0.1162
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0434 0.0818
Onchocerca volvulus 0.0061 0.0565 0.1606
Plasmodium falciparum calcium-dependent protein kinase 2 0.0066 0.0612 0.0597
Echinococcus granulosus solute carrier family 22 0.0061 0.0565 0.0551
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0273 0.0258
Giardia lamblia Sugar-proton symporter 0.0061 0.0565 0.1477
Loa Loa (eye worm) hypothetical protein 0.0036 0.028 0.0518
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0035 0.0273 0.0714
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.037 0.2661
Echinococcus granulosus neuropeptide s receptor 0.0035 0.0273 0.0258
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0112
Onchocerca volvulus 0.0035 0.0273 0.0714
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0611 0.0598
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0066 0.0612 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0611 0.1261
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0042 0.0071
Leishmania major telomerase reverse transcriptase, putative 0.0084 0.0819 0.5896
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0019 0.0091 0.0157
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0611 0.0598
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0075 0.0715 0.1081
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0014 0.0039 0.0046
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0273 0.0258
Treponema pallidum ATP-dependent DNA helicase 0.002 0.0099 0.0269
Echinococcus granulosus nAChR subunit 0.0014 0.0039 0.0024
Entamoeba histolytica hypothetical protein 0.0098 0.0978 0.2587
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0273 0.0544
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.028 0.0592
Echinococcus granulosus hypothetical protein 0.0035 0.0273 0.0258
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.028 0.056
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0056 0.0041
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0434 0.0885
Plasmodium falciparum telomerase reverse transcriptase 0.0084 0.0819 0.0804
Trichomonas vaginalis DNA polymerase II, putative 0.0019 0.0091 0.0191
Onchocerca volvulus 0.0061 0.0565 0.1606
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0035 0.0273 0.0503
Leishmania major hypothetical protein, conserved 0.0036 0.028 0.202
Brugia malayi Bloom's syndrome protein homolog 0.0065 0.0604 0.1244
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Plasmodium falciparum calcium-dependent protein kinase 5 0.0066 0.0612 0.0597
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Entamoeba histolytica recQ family DNA helicase 0.002 0.0099 0.0225
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Trypanosoma brucei THT1 - hexose transporter, putative 0.0135 0.1389 1
Plasmodium vivax DNA polymerase alpha, putative 0.0019 0.0091 0.0075
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Brugia malayi DNA polymerase delta catalytic subunit 0.0019 0.0091 0.0159
Echinococcus granulosus peptide allatostatin:somatostatin 0.0035 0.0273 0.0258
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.028 0.0266
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0014 0.0039 0.0046
Entamoeba histolytica recQ family helicase, putative 0.0044 0.037 0.0952
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Loa Loa (eye worm) hypothetical protein 0.0036 0.028 0.0518
Echinococcus granulosus neuropeptide receptor 0.0035 0.0273 0.0258
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0273 0.0258
Echinococcus multilocularis orexin receptor type 2 0.0035 0.0273 0.0258
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.028 0.1154
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0039 0.0024
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.017 0.1225
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0064 0.0597 0.123
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0019 0.0091 0.0191
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0039 0.0046
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0437 0.4742 0.474
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Schistosoma mansoni DNA polymerase eta 0.0014 0.0042 0.0056
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0059 0.0543 0.0528
Plasmodium falciparum protein kinase 7 0.0605 0.6617 0.6612
Echinococcus granulosus transcription factor eb 0.0107 0.1078 0.1065
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0019 0.0091 0.0159
Onchocerca volvulus 0.0061 0.0565 0.1606
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.028 0.0518
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Schistosoma mansoni DNA helicase recq5 0.0038 0.0309 0.062
Schistosoma mansoni DNA helicase recq1 0.0038 0.0309 0.062
Onchocerca volvulus 0.0061 0.0565 0.1606
Echinococcus granulosus neuropeptide receptor A26 0.0035 0.0273 0.0258
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0035 0.0273 0.0503
Loa Loa (eye worm) hypothetical protein 0.0052 0.0463 0.0874
Brugia malayi beta-lactamase 0.0036 0.028 0.056
Brugia malayi Cam kinase protein 1 0.0066 0.0611 0.1261
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0014 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0434 0.0818
Mycobacterium leprae conserved hypothetical protein 0.0036 0.028 0.1916
Onchocerca volvulus Putative transporter 0.0061 0.0565 0.1606
Brugia malayi beta-lactamase family protein 0.0036 0.028 0.056
Loa Loa (eye worm) hypothetical protein 0.0031 0.0226 0.0411
Entamoeba histolytica Flap nuclease, putative 0.0026 0.017 0.0415
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0039 0.0024
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0035 0.0273 0.0544
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0039 0.0024
Trypanosoma cruzi hexose transporter, putative 0.0135 0.1389 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.017 0.1225
Echinococcus granulosus g protein coupled receptor 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0115 0.0473
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Schistosoma mansoni flap endonuclease-1 0.0023 0.0142 0.0268
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0056 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Schistosoma mansoni hypothetical protein 0.0035 0.0273 0.0544
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0263 0.1897
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0035 0.0273 0.0503
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0273 0.0258
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0611 0.1165
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Onchocerca volvulus 0.0035 0.0273 0.0714
Brugia malayi Major Facilitator Superfamily protein 0.0061 0.0565 0.1162
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Trypanosoma cruzi hexose transporter, putative 0.0061 0.0565 0.4067
Echinococcus multilocularis somatostatin receptor 0.0035 0.0273 0.0258
Brugia malayi polk-prov protein 0.0031 0.0226 0.0445
Leishmania major glucose transporter/membrane transporter D2, putative 0.0135 0.1389 1
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0019 0.0091 0.0159
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0099 0.0177
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0273 0.0544
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0309 0.0466
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0273 0.0544
Schistosoma mansoni growth hormone secretagogue receptor 0.0035 0.0273 0.0544
Brugia malayi neuropeptide F receptor 0.0035 0.0273 0.0544
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0337 0.2299
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0807 0.8868 0.8879
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0039 0.005
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis nAChR subunit 0.0014 0.0039 0.0024
Schistosoma mansoni hypothetical protein 0.0169 0.1759 0.369
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0611 0.0598
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0035 0.0273 0.0544
Giardia lamblia Hexose transporter 0.0061 0.0565 0.1477
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0039 0.0024
Onchocerca volvulus 0.0036 0.028 0.0737
Trichomonas vaginalis glucose transporter, putative 0.0135 0.1389 0.2929
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0019 0.0091 0.0653
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0273 0.0258
Schistosoma mansoni histamine h1 receptor 0.0035 0.0273 0.0544
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0038 0.0309 0.0294
Echinococcus granulosus g protein coupled receptor 0.0035 0.0273 0.0258
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0039 0.0024
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0346 0.3734 0.5643
Brugia malayi hypothetical protein 0.0035 0.0273 0.0544
Mycobacterium ulcerans lipase LipD 0.0036 0.028 0.1916
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0064 0.0597 0.4077
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0019 0.0091 0.0075
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0597 0.123
Loa Loa (eye worm) hypothetical protein 0.0147 0.1521 0.2944
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.017 0.0359
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.3121 0.6581
Echinococcus granulosus alpha 1A adrenergic receptor 0.0035 0.0273 0.0258
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0035 0.0273 0.0544
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0033
Schistosoma mansoni protein kinase 0.0066 0.0611 0.1261
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0035 0.0273 0.0258
Brugia malayi ORL1-like opioid receptor 0.0035 0.0273 0.0544
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0016 0.0112
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0611 0.0598
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0042 0.0172
Schistosoma mansoni hypothetical protein 0.0035 0.0273 0.0544
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0565 0.1191
Schistosoma mansoni amine GPCR 0.0035 0.0273 0.0544
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0041 0.0333 0.1372
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Brugia malayi Cation transporter family protein 0.0014 0.0039 0.005
Schistosoma mansoni glucose transport protein 0.0437 0.4742 1
Echinococcus granulosus dro:myosuppressin receptor 0.0035 0.0273 0.0258
Onchocerca volvulus 0.0061 0.0565 0.1606
Loa Loa (eye worm) beta-lactamase 0.0036 0.028 0.0518
Plasmodium vivax CDK-related protein kinase 6, putative 0.0909 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0273 0.0258
Echinococcus granulosus GPCR family 2 0.0016 0.0056 0.0041
Mycobacterium ulcerans sugar transporter 0.0061 0.0565 0.3859
Brugia malayi hypothetical protein 0.0061 0.0565 0.1162
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0437 0.4742 0.474
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.028 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0565 0.1191
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0035 0.0273 0.0258
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0273 0.0258
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0019 0.0091 0.0202
Loa Loa (eye worm) sugar transporter 0.0061 0.0565 0.1074
Loa Loa (eye worm) hypothetical protein 0.0048 0.0414 0.0778
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0437 0.4742 0.474
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0035 0.0273 0.0544
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0337 0.2424
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0061 0.0565 0.2324
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0035 0.0273 0.0544
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0019 0.0091 0.0159
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Toxoplasma gondii DNA polymerase family B protein 0.0019 0.0091 0.0137
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0019 0.0091 0.0075
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0273 0.0258
Schistosoma mansoni hypothetical protein 0.0034 0.0259 0.0515
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Plasmodium falciparum calcium-dependent protein kinase 1 0.0066 0.0612 0.0597
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0019 0.0091 0.0075
Schistosoma mansoni nAChR subunit 0.0014 0.0039 0.005
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0064 0.0597 0.123
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0414 0.2978
Onchocerca volvulus 0.0035 0.0273 0.0714
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0039 0.005
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Echinococcus multilocularis dna polymerase eta 0.0014 0.0042 0.0026
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0309 0.062
Onchocerca volvulus 0.0035 0.0273 0.0714
Onchocerca volvulus 0.0036 0.028 0.0737
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0014 0.0039 0.0024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0039 0.005
Echinococcus granulosus allatostatin A receptor 0.0035 0.0273 0.0258
Onchocerca volvulus 0.0035 0.0273 0.0714
Brugia malayi G protein-coupled receptor F59B2.13 0.0035 0.0273 0.0544
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Plasmodium falciparum flap endonuclease 1 0.0026 0.017 0.0155
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0038 0.0309 0.0466
Schistosoma mansoni opsin-like receptor 0.0035 0.0273 0.0544
Echinococcus multilocularis calcium dependent protein kinase 0.0062 0.0566 0.0552
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Leishmania major hypothetical protein, conserved 0.0061 0.0565 0.4067
Schistosoma mansoni hypothetical protein 0.0035 0.0273 0.0544
Brugia malayi Sugar transporter family protein 0.0061 0.0565 0.1162
Echinococcus granulosus synaptic vesicle 2 protein 0.0061 0.0565 0.0551
Echinococcus granulosus g protein coupled receptor 0.0035 0.0273 0.0258
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0035 0.0273 0.0258
Trypanosoma brucei glucose transporter, putative 0.0135 0.1389 1
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0019 0.0091 0.0191
Brugia malayi GnHR receptor homolog 0.0035 0.0273 0.0544
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0099 0.0714
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0014 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0107 0.1072 0.2065
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0019 0.0091 0.0202
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0039 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0035 0.0273 0.0544
Trypanosoma cruzi hexose transporter, putative 0.0135 0.1389 1
Brugia malayi G protein-coupled receptor 0.0035 0.0273 0.0544
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0099 0.0714
Loa Loa (eye worm) hypothetical protein 0.0035 0.0273 0.0503
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.028 0.1154
Plasmodium falciparum calcium-dependent protein kinase 4 0.0066 0.0612 0.0597
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0414 0.0399
Trichomonas vaginalis sugar transporter, putative 0.0061 0.0565 0.1191
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0019 0.0091 0.0653
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Leishmania major protein kinase, putative 0.0066 0.0611 0.4403
Onchocerca volvulus 0.0061 0.0565 0.1606
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.028 0.1916
Schistosoma mansoni neuropeptide receptor 0.0035 0.0273 0.0544
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0061 0.0565 0.1162
Loa Loa (eye worm) hypothetical protein 0.0061 0.0565 0.1074
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.2431 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0273 0.0544
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0046

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 34 uM In vitro inhibitory concentration against human Acyl coenzyme A:cholesterol acyltransferase 1 expressed in Hi5 cells ChEMBL. 15603959
IC50 (binding) = 34 uM In vitro inhibitory concentration against human Acyl coenzyme A:cholesterol acyltransferase 1 expressed in Hi5 cells ChEMBL. 15603959
Inhibition (binding) = 33 % In vitro inhibition of human Acyl coenzyme A:cholesterol acyltransferase 2 expressed in Hi5 cells at 125 uM ChEMBL. 15603959
Inhibition (binding) = 33 % In vitro inhibition of human Acyl coenzyme A:cholesterol acyltransferase 2 expressed in Hi5 cells at 125 uM ChEMBL. 15603959

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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