Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0638 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.2104 | 1 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0077 | 0.0131 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0956 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.1598 | 0.7574 | 0.7571 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.0252 | 0.0319 |
Echinococcus multilocularis | tumor protein p63 | 0.0336 | 0.1524 | 0.2001 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0043 | 0.0043 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0021 | 0.0014 | 0.0004 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0806 | 0.3777 | 0.498 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.007 | 0.0252 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0005 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0021 | 0.0014 | 0.0061 |
Echinococcus granulosus | lamin | 0.0027 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0138 | 0.0252 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0066 | 0.0233 | 0.0293 |
Schistosoma mansoni | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.111 | 0.5235 | 0.6908 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.1041 | 0.2042 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.1598 | 0.7574 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0047 | 0.0138 | 0.0127 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0046 | 0.0136 | 0.0249 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0021 | 0.0014 | 0.0061 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0021 | 0.0014 | 0.0061 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0043 | 0.0043 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0488 | 0.2253 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.1598 | 0.7574 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.0252 | 0.0241 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.1212 | 0.238 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.0498 | 1 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1013 | 0.4771 | 0.9436 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0033 | 0.0072 | 0.0061 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0235 | 0.1041 | 0.1362 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0956 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0021 | 0.0014 | 0.0061 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0031 | 0.0064 | 0.007 |
Echinococcus multilocularis | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.1598 | 0.7574 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0064 | 0.0053 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.0498 | 0.0966 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0021 | 0.0014 | 0.0004 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.1598 | 0.7574 | 0.7571 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.015 | 0.0276 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.1212 | 0.1588 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0086 | 0.0099 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.007 | 0.0252 | 0.0319 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0252 | 0.0478 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0021 | 0.0014 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.0498 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0145 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0233 | 0.0439 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0031 | 0.0064 | 0.0067 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.0355 | 0.0455 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.1212 | 0.238 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0116 | 0.0139 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0066 | 0.0233 | 0.0222 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0066 | 0.0233 | 0.0222 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0034 | 0.0078 | 0.0085 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.0105 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0086 | 0.0099 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0121 | 0.0493 | 0.0638 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1073 | 0.5056 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0217 | 0.0407 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.014 | 0.0585 | 0.0759 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0235 | 0.1041 | 0.1362 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0053 | 0.0167 | 0.0206 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.0252 | 0.0319 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0047 | 0.0138 | 0.0168 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1013 | 0.4771 | 0.9436 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0053 | 0.0167 | 0.0202 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.2104 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0043 | 0.0043 |
Echinococcus granulosus | tumor protein p63 | 0.0336 | 0.1524 | 0.2001 |
Brugia malayi | hypothetical protein | 0.0122 | 0.0498 | 0.0644 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.0384 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0252 | 0.0478 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0021 | 0.0014 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0043 | 0.0064 |
Loa Loa (eye worm) | oxidoreductase | 0.0021 | 0.0014 | 0.0005 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0152 | 0.0187 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0021 | 0.0014 | 0.0004 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0066 | 0.0233 | 0.4515 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.1598 | 0.7574 | 0.7571 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0033 | 0.0072 | 0.0077 |
Chlamydia trachomatis | pyruvate kinase | 0.0066 | 0.0233 | 0.0089 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0066 | 0.0233 | 0.0289 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0021 | 0.0014 | 0.0004 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.1598 | 0.7574 | 0.7571 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.007 | 0.0252 | 0.0319 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0121 | 0.0493 | 0.0638 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0066 | 0.0233 | 0.4515 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0077 | 0.0087 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0116 | 0.0139 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1013 | 0.4771 | 0.6294 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0043 | 0.0064 |
Echinococcus granulosus | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0021 | 0.0014 | 0.0004 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.0384 | 0.0493 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Schistosoma mansoni | lamin | 0.0027 | 0.0043 | 0.0043 |
Plasmodium falciparum | pyruvate kinase | 0.0066 | 0.0233 | 0.0289 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0021 | 0.0014 | 0.0004 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.0252 | 0.0241 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0585 | 0.2717 | 0.3579 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0043 | 0.0043 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0217 | 0.0272 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0043 | 0.0043 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0043 | 0.0043 |
Echinococcus granulosus | dna polymerase eta | 0.0047 | 0.0138 | 0.0168 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Mycobacterium ulcerans | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0152 | 0.0187 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0384 | 0.0739 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0014 | 0.0004 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0638 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.007 | 0.0252 | 0.0319 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0121 | 0.0493 | 0.0483 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0121 | 0.0493 | 0.0634 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0043 | 0.0043 |
Onchocerca volvulus | 0.0027 | 0.0043 | 0.0608 | |
Loa Loa (eye worm) | pyruvate kinase | 0.0066 | 0.0233 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.0498 | 0.0966 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Brugia malayi | Isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.1598 | 0.7574 | 1 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0014 | 0.0003 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0064 | 0.0053 |
Loa Loa (eye worm) | pyruvate kinase | 0.0066 | 0.0233 | 0.0439 |
Schistosoma mansoni | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0525 | 0.2432 | 0.2424 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Schistosoma mansoni | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Leishmania major | pyruvate kinase | 0.0066 | 0.0233 | 0.0222 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0116 | 0.0208 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.0252 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0252 | 0.0478 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0031 | 0.0064 | 0.0285 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0718 | 0.3357 | 0.4425 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0043 | 0.0043 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0031 | 0.0064 | 0.0067 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0718 | 0.3357 | 0.4425 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0066 | 0.0233 | 0.0293 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0031 | 0.0064 | 0.0053 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1013 | 0.4771 | 0.6294 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0217 | 0.0407 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0152 | 0.028 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0121 | 0.0493 | 0.0634 |
Echinococcus multilocularis | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Onchocerca volvulus | 0.007 | 0.0252 | 0.4915 | |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Leishmania major | pyruvate kinase | 0.0066 | 0.0233 | 0.0222 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0011 | 0.0049 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0217 | 0.0272 |
Plasmodium vivax | pyruvate kinase, putative | 0.0066 | 0.0233 | 0.0289 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.1598 | 0.7574 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.014 | 0.0585 | 0.0759 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0585 | 0.2717 | 0.3578 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.1212 | 0.1588 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0086 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0041 | 0.0059 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.1212 | 0.1588 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0525 | 0.2432 | 0.2424 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0047 | 0.0138 | 0.0127 |
Echinococcus granulosus | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Loa Loa (eye worm) | pyruvate kinase | 0.0066 | 0.0233 | 0.0439 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 0.7571 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0109 | 0.0129 |
Brugia malayi | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0064 | 0.0053 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0121 | 0.0493 | 0.0638 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.0355 | 0.0455 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.0252 | 0.0319 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0053 | 0.0167 | 0.0202 |
Schistosoma mansoni | DNA polymerase eta | 0.0047 | 0.0138 | 0.0168 |
Onchocerca volvulus | 0.0048 | 0.0145 | 0.2698 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0021 | 0.0014 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0144 | 0.0176 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0046 | 0.0136 | 0.0166 |
Giardia lamblia | Pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0145 | 0.0177 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.007 | 0.0252 | 0.0319 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.0252 | 0.0319 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0031 | 0.0064 | 0.0053 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0005 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.007 | 0.0252 | 0.0319 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0525 | 0.2432 | 0.2424 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0066 | 0.0233 | 0.0222 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0066 | 0.0233 | 0.4515 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1073 | 0.5056 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0099 | 0.0391 | 0.0502 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0021 | 0.0014 | 0.0061 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0005 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0116 | 0.0139 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.0252 | 0.0319 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.007 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0043 | 0.0064 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0217 | 0.0272 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.0384 | 0.0493 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0525 | 0.2432 | 0.2424 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0483 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0053 | 0.0167 | 0.074 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0064 | 0.0067 |
Leishmania major | DNA polymerase eta, putative | 0.0047 | 0.0138 | 0.0127 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0021 | 0.0014 | 0.0004 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0116 | 0.0139 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0014 | 0.0061 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1598 | 0.7574 | 1 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0021 | 0.0014 | 0.0061 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0066 | 0.0233 | 0.1032 |
Loa Loa (eye worm) | hypothetical protein | 0.1013 | 0.4771 | 0.9436 |
Leishmania major | DNA polymerase eta, putative | 0.0033 | 0.0072 | 0.0061 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0217 | 0.0272 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Echinococcus granulosus | pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0116 | 0.0139 |
Echinococcus multilocularis | dna polymerase eta | 0.0047 | 0.0138 | 0.0168 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0077 | 0.0087 |
Schistosoma mansoni | lamin | 0.0027 | 0.0043 | 0.0043 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.1598 | 0.7574 | 0.7571 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0153 | 0.0679 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0525 | 0.2432 | 0.2424 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0121 | 0.0493 | 0.0634 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.007 | 0.0252 | 0.1063 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0152 | 0.028 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0066 | 0.0233 | 0.0222 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.0252 | 0.0241 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0005 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1013 | 0.4771 | 0.6294 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0525 | 0.2432 | 0.3202 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0121 | 0.0493 | 0.0483 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.015 | 0.0184 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.1598 | 0.7574 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0086 | 0.0099 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0021 | 0.0014 | 0.0004 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0121 | 0.0493 | 0.0483 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0034 | 0.0078 | 0.0085 |
Onchocerca volvulus | 0.0049 | 0.015 | 0.2819 | |
Echinococcus granulosus | microtubule associated protein 2 | 0.0718 | 0.3357 | 0.4425 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.007 | 0.0252 | 0.0319 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0121 | 0.0493 | 0.0638 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0014 | 0.0004 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0136 | 0.0249 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0014 | 0.0003 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.007 | 0.0252 | 0.1118 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0066 | 0.0233 | 0.0293 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0116 | 0.0139 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0011 | 0.0049 |
Echinococcus multilocularis | pyruvate kinase | 0.0052 | 0.0166 | 0.0204 |
Onchocerca volvulus | 0.0027 | 0.0043 | 0.0608 | |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0167 | 0.0309 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0217 | 0.0272 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0145 | 0.0177 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0217 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0116 | 0.0208 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0121 | 0.0493 | 0.0638 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.0252 | 0.0319 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0034 | 0.0078 | 0.0085 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0014 | 0.0004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0116 | 0.0139 |
Giardia lamblia | Pyruvate kinase | 0.0066 | 0.0233 | 0.0293 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.0384 | 0.0493 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.2104 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0235 | 0.1041 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0161 | 0.0298 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.007 | 0.0252 | 0.1118 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0066 | 0.0233 | 0.0977 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.1598 | 0.7574 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.0034 | 0.0078 | 0.0088 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1013 | 0.4771 | 0.6294 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.007 | 0.0252 | 0.1063 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0488 | 0.2253 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0217 | 0.0407 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.1212 | 0.1588 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Diuretic activity (functional) | = 250 | Salidiuretic activity in dog following i.v. dosing at 5 mg/kg | ChEMBL. | 7452697 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.