Detailed information for compound 545205

Basic information

Technical information
  • TDR Targets ID: 545205
  • Name: disodium oxido carbonate
  • MW: 124.004 | Formula: CH2Na2O4
  • H donors: 0 H acceptors: 3 LogP: 0.27 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]OC(=O)[O-].[NaH+].[NaH+]
  • InChi: 1S/CH2O4.2Na/c2-1(3)5-4;;/h4H,(H,2,3);;/q;2*+1/p-2
  • InChiKey: UDYLZILYVRMCJW-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

  • disodium oxidanidyl carbonate
  • sodium percarbonate
  • 14455-47-1
  • 4452-58-8
  • Carbonoperoxoic acid, disodium salt

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0023 0.008 0.018
Leishmania major hypothetical protein, conserved 0.0023 0.008 0.0103
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0403
Schistosoma mansoni nuclear hormone receptor 0.002 0.0061 0.0058
Entamoeba histolytica heat shock protein 90, putative 0.0023 0.008 0.0203
Loa Loa (eye worm) hypothetical protein 0.0083 0.0488 0.1405
Brugia malayi kinase, mitochondrial precursor 0.0413 0.2744 0.7945
Schistosoma mansoni ets-related 0.0012 0.0006 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0061 0.0168
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0061 0.0055
Schistosoma mansoni heat shock protein 0.0023 0.008 0.0076
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0081 0.0215
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0009
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.084 0.2428
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0061 0.0159
Plasmodium falciparum thioredoxin reductase 0.0081 0.0474 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0061 0.0159
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0359 0.2376 0.6878
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0413 0.2744 0.274
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.031 0.1119
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.002 0.0017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Schistosoma mansoni hypothetical protein 0.0012 0.0006 0.0003
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0028 0.0114 0.0111
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0028 0.0114 0.1066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0061 0.0055
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0042 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.002 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Onchocerca volvulus 0.0083 0.0488 0.139
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0028 0.0114 0.0191
Toxoplasma gondii ABC1 family protein 0.0083 0.0488 0.4574
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0023 0.008 0.0204
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0083 0.0488 0.1397
Schistosoma mansoni survival motor neuron protein 0.0047 0.0244 0.0241
Echinococcus multilocularis microtubule associated protein 2 0.1475 1 1
Mycobacterium ulcerans lipase LipD 0.0083 0.0488 0.2279
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0066 0.0373 0.1348
Toxoplasma gondii histone lysine methyltransferase SET1 0.0109 0.0665 0.6236
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0081 0.0206
Mycobacterium leprae Probable lipase LipE 0.0083 0.0488 0.2279
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0052 0.0046
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0023 0.008 0.0196
Brugia malayi TAR-binding protein 0.0068 0.039 0.1113
Trichomonas vaginalis mercuric reductase, putative 0.0028 0.0114 0.0268
Mycobacterium ulcerans hypothetical protein 0.0083 0.0488 0.2279
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.017 0.0474
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0061 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0011 0.0006
Brugia malayi Probable DNA topoisomerase II 0.0023 0.008 0.0213
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0081 0.0183
Brugia malayi hypothetical protein 0.0037 0.0172 0.0482
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Schistosoma mansoni hypothetical protein 0.0036 0.017 0.0167
Schistosoma mansoni ets-related 0.0256 0.1675 0.1672
Loa Loa (eye worm) hypothetical protein 0.0083 0.0488 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0163 0.016
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0028 0.0114 0.0107
Brugia malayi Importin beta-1 subunit 0.0034 0.0152 0.0424
Brugia malayi Ets-domain containing protein 0.0084 0.05 0.1432
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0081 0.0106
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0011 0.0006
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0023 0.008 0.0279
Plasmodium vivax heat shock protein 86, putative 0.0023 0.008 0.1631
Trichomonas vaginalis sensor histidine kinase, putative 0.0023 0.008 0.018
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.084 0.2428
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0063 0.0164
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0061 0.0159
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0081 0.0678
Treponema pallidum fructose-bisphosphate aldolase 0.0584 0.3909 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0416 0.1197
Plasmodium vivax hypothetical protein, conserved 0.0023 0.008 0.1631
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0229
Plasmodium vivax importin-beta 2, putative 0.0034 0.0152 0.3125
Schistosoma mansoni cpg binding protein 0.0061 0.0337 0.0334
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0178 0.055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0011 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0061 0.0159
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0083 0.0488 0.1405
Toxoplasma gondii heat shock protein HSP90 0.0023 0.008 0.0746
Schistosoma mansoni microtubule-associated protein tau 0.1475 1 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0184 0.118 0.3189
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0011 0.0006
Echinococcus multilocularis GPCR, family 2 0.0036 0.017 0.0163
Loa Loa (eye worm) endoplasmin 0.0023 0.008 0.0222
Echinococcus granulosus cpg binding protein 0.0061 0.0337 0.0331
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0003 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.002 0.0014
Trypanosoma cruzi trypanothione reductase, putative 0.0028 0.0114 0.0403
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0061 0.0159
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0023 0.008 0.0279
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0018
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0064 0.0363 0.1043
Plasmodium falciparum heat shock protein 90 0.0023 0.008 0.0654
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0009 0.0008
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0413 0.2744 0.274
Leishmania major cathepsin L-like protease 0.0072 0.0415 0.135
Mycobacterium tuberculosis Probable hydrolase 0.0083 0.0488 0.1182
Brugia malayi hypothetical protein 0.0065 0.0365 0.104
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0061 0.0168
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0274 0.0268
Toxoplasma gondii NADPH-glutathione reductase 0.0028 0.0114 0.1066
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0092 0.0323
Brugia malayi beta-lactamase family protein 0.0083 0.0488 0.1397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0011 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Trichomonas vaginalis penicillin-binding protein, putative 0.0083 0.0488 0.1227
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0028 0.0114 0.0107
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0274 0.0786
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0208 0.0747
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Treponema pallidum NADH oxidase 0.0028 0.0114 0.0283
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0061 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0111 0.0262
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0109 0.0256
Schistosoma mansoni pyruvate dehydrogenase 0.039 0.2587 0.2585
Schistosoma mansoni endoplasmin 0.0023 0.008 0.0076
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0044 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0028 0.0111 0.0395
Mycobacterium tuberculosis Probable reductase 0.0184 0.118 0.3189
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0061 0.0159
Mycobacterium ulcerans beta-lactamase 0.0083 0.0488 0.2279
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0403
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0061 0.0058
Echinococcus granulosus neuropeptide s receptor 0.0539 0.3608 0.3604
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0023 0.0081 0.0074
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0152 0.0146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0208 0.0579
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0403
Mycobacterium tuberculosis Conserved protein 0.0083 0.0488 0.1182
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0488 0.1768
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0172 0.0348
Brugia malayi beta-lactamase 0.0083 0.0488 0.1397
Plasmodium vivax glutathione reductase, putative 0.0081 0.0474 0.9722
Schistosoma mansoni heat shock protein 0.0023 0.008 0.0076
Echinococcus granulosus snurportin 1 0.0359 0.2376 0.2371
Onchocerca volvulus 0.0083 0.0488 0.139
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0023 0.008 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0052 0.0142
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0415 0.1504
Plasmodium falciparum ataxin-2 like protein, putative 0.0057 0.0309 0.61
Trichomonas vaginalis adenylate cyclase, putative 0.0028 0.0111 0.0262
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0415 0.1504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Schistosoma mansoni hypothetical protein 0.0035 0.0163 0.016
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0061 0.0055
Onchocerca volvulus 0.0019 0.0052 0.0124
Brugia malayi hypothetical protein 0.0231 0.15 0.4334
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0825 0.0822
Brugia malayi hypothetical protein 0.0064 0.0363 0.1034
Loa Loa (eye worm) thioredoxin reductase 0.0081 0.0474 0.1365
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0584 0.3909 1
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Trypanosoma cruzi Heat shock protein 83, putative 0.0023 0.008 0.0279
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0111 0.0395
Toxoplasma gondii thioredoxin reductase 0.0081 0.0474 0.4447
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0111 0.0262
Echinococcus granulosus bloom syndrome protein 0.0023 0.0081 0.0074
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0584 0.3909 1
Echinococcus multilocularis neuropeptide receptor A26 0.0539 0.3608 0.3604
Schistosoma mansoni hypothetical protein 0.0078 0.0456 0.0453
Leishmania major hypothetical protein, conserved 0.0083 0.0488 0.1618
Echinococcus granulosus beta LACTamase domain containing family member 0.0083 0.0488 0.0482
Echinococcus granulosus thioredoxin glutathione reductase 0.0082 0.0481 0.0475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0061 0.0168
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0012 0.0003 0.0063
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0222
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0184 0.118 0.3189
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0132 0.0825 0.0819
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Echinococcus granulosus heat shock protein 0.0023 0.008 0.0073
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0109 0.0256
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0006 0.0009
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0413 0.2744 1
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.008 0.0279
Onchocerca volvulus Protein cycle homolog 0.0065 0.0365 0.1033
Loa Loa (eye worm) hypothetical protein 0.0517 0.3452 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0061 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0061 0.0159
Trypanosoma brucei PAB1-binding protein , putative 0.0057 0.0309 0.0863
Brugia malayi hypothetical protein 0.0092 0.0552 0.1582
Loa Loa (eye worm) runx1 0.0065 0.0365 0.105
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0052 0.0046
Schistosoma mansoni DNA helicase recq1 0.0023 0.0081 0.0077
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0025 0.0092 0.086
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0081 0.0183
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0111 0.0262
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0023 0.008 0.0746
Schistosoma mansoni thyroid hormone receptor 0.002 0.0061 0.0058
Loa Loa (eye worm) TOPoisomerase family member 0.0023 0.008 0.0222
Entamoeba histolytica cysteine protease, putative 0.0019 0.0052 0.0133
Echinococcus multilocularis tar DNA binding protein 0.0068 0.039 0.0384
Trypanosoma cruzi heat shock protein 85, putative 0.0023 0.008 0.0279
Echinococcus granulosus FTZ F1 alpha 0.002 0.0061 0.0055
Brugia malayi Latrophilin receptor protein 2 0.0036 0.017 0.0474
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.008 0.0279
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0172 0.044
Onchocerca volvulus 0.0083 0.0488 0.139
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.017 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Trichomonas vaginalis heat shock protein, putative 0.0023 0.008 0.018
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0114 0.0703 0.2029
Brugia malayi Calcitonin receptor-like protein seb-1 0.0114 0.0703 0.2022
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0208 0.0509
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0172 0.0166
Mycobacterium ulcerans esterase/lipase LipP 0.0083 0.0488 0.2279
Echinococcus multilocularis thioredoxin glutathione reductase 0.0082 0.0481 0.0475
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.039 0.1113
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0061 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0061 0.0159
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0023 0.008 0.018
Plasmodium falciparum importin beta, putative 0.0034 0.0152 0.238
Onchocerca volvulus 0.0047 0.0244 0.0683
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0208 0.0747
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0152 0.0273
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0061 0.0058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0274 0.0268
Toxoplasma gondii heat shock protein 90, putative 0.0023 0.008 0.0746
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0167 0.1066 1
Brugia malayi hypothetical protein 0.0057 0.0309 0.088
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0285 0.187 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0052 0.0046
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0052 0.0124
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0111 0.0395
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0205 0.1321 0.3595
Entamoeba histolytica hypothetical protein 0.0027 0.0109 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0057 0.0309 0.61
Plasmodium vivax vivapain-2 0.0019 0.0052 0.1064
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0184 0.118 0.3189
Echinococcus multilocularis cysteine protease 0.0019 0.0052 0.0046
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0061 0.0058
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0028 0.0114 0.0229
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0528 0.3532 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0208 0.0717
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0061 0.0055
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0023 0.0081 0.0074
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0028 0.0114 0.0191
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0023 0.0081 0.0225
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Giardia lamblia Fructose-bisphosphate aldolase 0.0584 0.3909 1
Brugia malayi ecdysteroid receptor 0.002 0.0061 0.0159
Entamoeba histolytica hypothetical protein 0.0035 0.0163 0.0416
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0172 0.0166
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0061 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Trichomonas vaginalis esterase, putative 0.0083 0.0488 0.1227
Schistosoma mansoni hypothetical protein 0.0036 0.017 0.0167
Schistosoma mansoni DNA helicase recq5 0.0023 0.0081 0.0077
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0083 0.0488 0.0485
Leishmania major developmentally regulated phosphoprotein-like protein 0.0413 0.2744 1
Trichomonas vaginalis D-aminoacylase, putative 0.0083 0.0488 0.1227
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.00000000018881
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0152 0.1429
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0061 0.0058
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0208 0.195
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0028 0.0114 0.0312
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0023 0.008 0.018
Brugia malayi Cathepsin L-like precursor 0.0019 0.0052 0.0132
Trichomonas vaginalis heat shock protein, putative 0.0023 0.008 0.018
Plasmodium falciparum thioredoxin reductase 0.0028 0.0114 0.1463
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0084 0.05 0.144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0274 0.0271
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0096 0.009
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0044 0.0118
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0061 0.0151
Onchocerca volvulus 0.0019 0.0052 0.0124
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0132 0.0825 0.2159
Entamoeba histolytica hypothetical protein 0.0035 0.0163 0.0416
Onchocerca volvulus 0.0019 0.0052 0.0124
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0028 0.0114 0.0107
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Echinococcus granulosus GA binding protein alpha chain 0.0084 0.05 0.0494
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Brugia malayi Cathepsin L-like precursor 0.0019 0.0052 0.0132
Trichomonas vaginalis receptor histidine kinase, putative 0.0023 0.008 0.018
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0144 0.0909 0.8528
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0028 0.0114 0.0191
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0111 0.0395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0081 0.0283
Schistosoma mansoni aryl hydrocarbon receptor 0.0028 0.0114 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0111 0.0262
Mycobacterium tuberculosis Probable lipase LipE 0.0083 0.0488 0.1182
Loa Loa (eye worm) glutathione reductase 0.0081 0.0474 0.1365
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0023 0.0081 0.0074
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0023 0.008 0.0213
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0061 0.0168
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.017 0.0163
Leishmania major protein kinase, putative 0.0028 0.0111 0.0221
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0114 0.0128
Schistosoma mansoni importin beta-1 0.0034 0.0152 0.0149
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0092 0.0248
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0052 0.0133
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0052 0.0124
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0028 0.0111 0.0262
Trypanosoma cruzi PAB1-binding protein , putative 0.0057 0.0309 0.1118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0274 0.0268
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0132 0.0825 0.0819
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0274 0.0268
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0028 0.0114 0.1463
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0172 0.0242
Schistosoma mansoni hypothetical protein 0.0025 0.0096 0.0093
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0081 0.0215
Plasmodium falciparum DNA gyrase subunit B 0.0023 0.008 0.0654
Mycobacterium leprae Possible regulatory protein 0.0028 0.0111 0.0178
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0083 0.0488 0.1182
Onchocerca volvulus 0.0019 0.0052 0.0124
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0205 0.1321 0.6933
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0096 0.009
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0172 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Plasmodium vivax DNA topoisomerase II, putative 0.0023 0.008 0.1631
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0065 0.0365 0.1049
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0172 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0061 0.0159
Schistosoma mansoni hypothetical protein 0.0012 0.0006 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0009 0.0006
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0172 0.0166
Schistosoma mansoni hypothetical protein 0.0036 0.017 0.0167
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Entamoeba histolytica Ran family GTPase 0.0025 0.0092 0.0235
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0274 0.0271
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0111 0.0221
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0114 0.0703 0.2022
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0083 0.0488 0.2279
Brugia malayi MH2 domain containing protein 0.0134 0.084 0.242
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0065 0.0365 0.104
Loa Loa (eye worm) hypothetical protein 0.0083 0.0488 0.1405
Onchocerca volvulus 0.0517 0.3452 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0063 0.0164
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Schistosoma mansoni tar DNA-binding protein 0.0068 0.039 0.0387
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0028 0.0114 0.0107
Leishmania major cathepsin L-like protease 0.0072 0.0415 0.135
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0184 0.118 0.3189
Trypanosoma cruzi DNA topoisomerase II, putative 0.0023 0.008 0.0279
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Leishmania major protein kinase, putative 0.0028 0.0111 0.0221
Onchocerca volvulus 0.0092 0.0552 0.1575
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0061 0.0058
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0114 0.2661
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0061 0.0159
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0109 0.0386
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0132 0.0825 0.2871
Brugia malayi PAS domain containing protein 0.0028 0.0111 0.0305
Trichomonas vaginalis D-aminoacylase, putative 0.0083 0.0488 0.1227
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0208 0.0202
Trypanosoma cruzi trypanothione reductase, putative 0.0081 0.0474 0.1718
Loa Loa (eye worm) hypothetical protein 0.0057 0.0309 0.0888
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0061 0.0159
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0052 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0403
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0109 0.0256
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0152 0.0273
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0028 0.0111 0.0395
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0028 0.0111 0.0262
Schistosoma mansoni coup transcription factor 0.002 0.0061 0.0058
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0061 0.0055
Trypanosoma cruzi heat shock protein 85, putative 0.0023 0.008 0.0279
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0023 0.008 0.0204
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0061 0.0055
Echinococcus multilocularis cpg binding protein 0.0061 0.0337 0.0331
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Plasmodium falciparum glutathione reductase 0.0028 0.0114 0.1463
Schistosoma mansoni hypothetical protein 0.0359 0.2376 0.2373
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0006 0.0003
Brugia malayi Ets-domain containing protein 0.0084 0.05 0.1432
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Loa Loa (eye worm) inositol-1 0.0042 0.0208 0.0594
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0052 0.0124
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0488 0.1768
Trypanosoma brucei hypothetical protein, conserved 0.0083 0.0488 0.1531
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0314 0.0902
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0006 0.0009
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0208 0.0509
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0825 0.0822
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0061 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0172 0.0418
Loa Loa (eye worm) hypothetical protein 0.0064 0.0363 0.1043
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Entamoeba histolytica hypothetical protein 0.0035 0.0163 0.0416
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0081 0.0755
Giardia lamblia NADH oxidase lateral transfer candidate 0.0028 0.0114 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.0052 0.0142
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0081 0.0215
Brugia malayi Cathepsin L-like precursor 0.0019 0.0052 0.0132
Brugia malayi hypothetical protein 0.0517 0.3452 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0028 0.0114 0.0229
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Brugia malayi Thioredoxin reductase 0.0081 0.0474 0.1357
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0172 0.0481
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0403
Echinococcus multilocularis heat shock protein 90 0.0023 0.008 0.0073
Schistosoma mansoni inositol monophosphatase 0.0042 0.0208 0.0205
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.017 0.0163
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0172 0.0418
Onchocerca volvulus 0.0057 0.0314 0.0886
Loa Loa (eye worm) heat shock protein 90 0.0023 0.008 0.0222
Loa Loa (eye worm) ctsf protein 0.0019 0.0052 0.0142
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0208 0.0202
Brugia malayi Cathepsin L-like precursor 0.0019 0.0052 0.0132
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0081 0.0183
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.15 0.1495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Schistosoma mansoni lozenge 0.0065 0.0365 0.0362
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0023 0.0081 0.0074
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Brugia malayi RNA, U transporter 1 0.0096 0.0576 0.1653
Schistosoma mansoni pyruvate dehydrogenase 0.0413 0.2744 0.2742
Loa Loa (eye worm) hypothetical protein 0.0078 0.0456 0.1313
Schistosoma mansoni pyruvate dehydrogenase 0.039 0.2587 0.2585
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0081 0.0474 0.1143
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0081 0.0074
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0274 0.0271
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0025 0.0092 0.0032
Schistosoma mansoni DNA topoisomerase II 0.0023 0.008 0.0076
Leishmania major mitochondrial DNA topoisomerase II 0.0023 0.008 0.0103
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0184 0.118 0.3189
Giardia lamblia Sgs1 DNA helicase, putative 0.0023 0.0081 0.0003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0052 0.0046
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0083 0.0488 0.1182
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Echinococcus granulosus geminin 0.0695 0.4673 0.467
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Loa Loa (eye worm) hypothetical protein 0.0036 0.017 0.0483
Loa Loa (eye worm) TAR-binding protein 0.0068 0.039 0.1121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0052 0.0049
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0172 0.0169
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0092 0.0257
Entamoeba histolytica heat shock protein 90, putative 0.0023 0.008 0.0203
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0061 0.0058
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0285 0.187 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0061 0.0055
Trichomonas vaginalis receptor histidine kinase, putative 0.0023 0.008 0.018
Mycobacterium tuberculosis Probable esterase LipL 0.0083 0.0488 0.1182
Schistosoma mansoni tar DNA-binding protein 0.0068 0.039 0.0387
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.017 0.0163
Loa Loa (eye worm) hypothetical protein 0.0413 0.2744 0.7947
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0028 0.0114 0.0128
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0061 0.0055
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0061 0.0055
Brugia malayi heat shock protein 90 0.0023 0.008 0.0213
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0061 0.0055
Loa Loa (eye worm) hypothetical protein 0.0083 0.0488 0.1405
Brugia malayi latrophilin 2 splice variant baaae 0.0078 0.0456 0.1305
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0081 0.0755
Plasmodium falciparum glutathione reductase 0.0081 0.0474 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0205 0.1321 0.3595
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0061 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0061 0.0159
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0061 0.0151
Echinococcus multilocularis cysteine protease 0.0019 0.0052 0.0046
Schistosoma mansoni inositol monophosphatase 0.0042 0.0208 0.0205
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0064 0.0363 0.1043
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0009
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0413 0.2744 0.274
Loa Loa (eye worm) hypothetical protein 0.0092 0.0552 0.159
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0052 0.0132
Trichomonas vaginalis DNA topoisomerase II, putative 0.0023 0.008 0.018
Echinococcus granulosus aryl hydrocarbon receptor 0.0092 0.0554 0.0548
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0061 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0825 0.4162
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0061 0.0159
Brugia malayi RNA binding protein 0.0068 0.039 0.1113
Brugia malayi Cathepsin L-like precursor 0.0013 0.0009 0.0008
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0061 0.0058
Brugia malayi glutathione reductase 0.0081 0.0474 0.1357
Entamoeba histolytica recQ family DNA helicase 0.0012 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.0222
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0825 0.4162
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0415 0.1504
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0018
Schistosoma mansoni ran 0.0025 0.0092 0.0089
Echinococcus multilocularis geminin 0.0695 0.4673 0.467
Trichomonas vaginalis glutathione reductase, putative 0.0028 0.0114 0.0268
Onchocerca volvulus 0.0019 0.0052 0.0124
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Trypanosoma brucei trypanothione reductase 0.0081 0.0474 0.1481
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0172 0.0166
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0114 0.0403
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0081 0.0004
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0023 0.008 0.0654
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.039 0.1121
Loa Loa (eye worm) hypothetical protein 0.0037 0.0172 0.049
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0044 0.0038
Echinococcus granulosus dnaJ subfamily B 0.0817 0.5502 0.5499
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0163 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Echinococcus multilocularis GA binding protein alpha chain 0.0084 0.05 0.0494
Echinococcus granulosus importin subunit beta 1 0.0034 0.0152 0.0146
Loa Loa (eye worm) fibroinase 0.0019 0.0052 0.0142
Leishmania major cathepsin L-like protease 0.0072 0.0415 0.135
Leishmania major importin beta-1 subunit, putative 0.0027 0.0109 0.0212
Schistosoma mansoni tar DNA-binding protein 0.0068 0.039 0.0387
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0011 0.0006
Echinococcus multilocularis heat shock protein 0.0023 0.008 0.0073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0114 0.0403
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0023 0.008 0.0073
Trypanosoma cruzi DNA topoisomerase II, putative 0.0023 0.008 0.0279
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0274 0.0778
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0092 0.0323
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0172 0.0447
Echinococcus granulosus tar DNA binding protein 0.0068 0.039 0.0384
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0011 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0023 0.008 0.018
Trypanosoma cruzi PAB1-binding protein , putative 0.0057 0.0309 0.1118
Trichomonas vaginalis endoplasmin, putative 0.0023 0.008 0.018
Onchocerca volvulus 0.0019 0.0052 0.0124
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0051 0.0268 1
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0065 0.0365 0.104
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0111 0.0262
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0052 0.011
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0052 0.0178
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0023 0.008 0.0746
Plasmodium falciparum DNA topoisomerase 2 0.0023 0.008 0.0654
Plasmodium vivax endoplasmin, putative 0.0023 0.008 0.1631
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.017 0.0483
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0025 0.0092 0.0046
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0092 0.0554 0.1596
Schistosoma mansoni ets 0.0012 0.0006 0.0003
Brugia malayi Cathepsin L-like precursor 0.0013 0.0009 0.0008
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0111 0.0395
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0028 0.0114 0.2331
Echinococcus multilocularis dnaJ subfamily B 0.0817 0.5502 0.5499
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0065 0.0365 0.0362
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0825 0.4162
Brugia malayi beta-lactamase family protein 0.0083 0.0488 0.1397
Toxoplasma gondii DNA topoisomerase 2, putative 0.0023 0.008 0.0746
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0415 0.1504
Brugia malayi Inositol-1 0.0042 0.0208 0.0585
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0028 0.0114 0.0099
Schistosoma mansoni elf1 0.0012 0.0006 0.0003
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0052 0.0046
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0061 0.0055
Echinococcus granulosus heat shock protein 90 0.0023 0.008 0.0073
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0083 0.0488 0.1182
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0028 0.0114 0.0128
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0163 0.0156
Loa Loa (eye worm) RNA binding protein 0.0068 0.039 0.1121
Trypanosoma brucei developmentally regulated phosphoprotein 0.0413 0.2744 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0208 0.0532
Schistosoma mansoni cpg binding protein 0.0061 0.0337 0.0334
Loa Loa (eye worm) hypothetical protein 0.0517 0.3452 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.0488 0.1405
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0023 0.008 0.0196
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0061 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0068 0.039 0.0387
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0229
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0184 0.118 0.6149
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0052 0.0142
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0023 0.008 0.0279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0011 0.0006
Loa Loa (eye worm) hypothetical protein 0.0083 0.0488 0.1405
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0208 0.0482
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0023 0.008 0.0213
Echinococcus granulosus GPCR family 2 0.0036 0.017 0.0163
Brugia malayi CXXC zinc finger family protein 0.0057 0.0314 0.0894
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0028 0.0114 0.1808
Mycobacterium tuberculosis Probable oxidoreductase 0.0205 0.1321 0.3595
Echinococcus multilocularis Protein lozenge 0.0065 0.0365 0.0359
Mycobacterium tuberculosis Conserved protein 0.0083 0.0488 0.1182
Trichomonas vaginalis helicase, putative 0.0013 0.0011 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0052 0.011
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0092 0.0085
Toxoplasma gondii LsmAD domain-containing protein 0.0057 0.0309 0.2902
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Schistosoma mansoni hypothetical protein 0.0817 0.5502 0.5501
Loa Loa (eye worm) hypothetical protein 0.0231 0.15 0.434
Schistosoma mansoni endoplasmin 0.0023 0.008 0.0076
Brugia malayi hypothetical protein 0.0035 0.0163 0.0454
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0114 0.0403
Brugia malayi nuclear receptor NHR-88 0.002 0.0061 0.0159
Loa Loa (eye worm) fli-1 protein 0.0256 0.1675 0.4846
Leishmania major DNA topoisomerase ii 0.0023 0.008 0.0103
Leishmania major hypothetical protein, conserved 0.0057 0.0309 0.0956
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0028 0.0114 0.1463
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0052 0.011
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0006 0.0009
Echinococcus multilocularis aryl hydrocarbon receptor 0.0092 0.0554 0.0548
Plasmodium vivax ataxin-2 like protein, putative 0.0057 0.0309 0.6345
Plasmodium falciparum endoplasmin, putative 0.0023 0.008 0.0654
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0415 0.126
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0092 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0061 0.0168
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0052 0.0046
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0114 0.2661
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0052 0.0133
Schistosoma mansoni hypothetical protein 0.0695 0.4673 0.4671
Brugia malayi cathepsin L-like precursor 0.0013 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0061 0.0159
Trichomonas vaginalis ran, putative 0.0025 0.0092 0.0212
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0092 0.188
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0023 0.008 0.0204
Toxoplasma gondii aldehyde dehydrogenase 0.0132 0.0825 0.7738
Brugia malayi Fli-1 protein 0.0256 0.1675 0.4841
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0023 0.0081 0.0678
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0208 0.0509
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0144 0.0909 0.3184
Loa Loa (eye worm) hypothetical protein 0.0023 0.0081 0.0225
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Loa Loa (eye worm) hypothetical protein 0.0064 0.0363 0.1043
Brugia malayi Endoplasmin precursor 0.0023 0.008 0.0213
Entamoeba histolytica hypothetical protein 0.0035 0.0163 0.0416
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0285 0.187 0.5186
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0028 0.0114 0.2331
Toxoplasma gondii cathepsin CPL 0.0019 0.0052 0.0487
Schistosoma mansoni thyroid hormone receptor 0.002 0.0061 0.0058
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0061 0.0168
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0178 0.0285
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.15 0.1495
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0753 0.0751
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0009 0.0023
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0144 0.0909 0.3113
Echinococcus multilocularis beta LACTamase domain containing family member 0.0083 0.0488 0.0482
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Schistosoma mansoni tar DNA-binding protein 0.0068 0.039 0.0387
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0061 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0061 0.0168
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0244 0.0691
Plasmodium vivax vivapain-2 0.0019 0.0052 0.1064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0114 0.0128
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0172 0.0166
Echinococcus multilocularis neuropeptide s receptor 0.0539 0.3608 0.3604
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0092 0.0943
Echinococcus granulosus neuropeptide receptor A26 0.0539 0.3608 0.3604
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0111 0.0262
Echinococcus granulosus cathepsin l1 0.0019 0.0052 0.0046
Onchocerca volvulus 0.0019 0.0052 0.0124
Mycobacterium tuberculosis Probable lipase LipD 0.0083 0.0488 0.1182
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0061 0.0159
Plasmodium vivax DNA gyrase subunit B, putative 0.0023 0.008 0.1631
Mycobacterium leprae conserved hypothetical protein 0.0083 0.0488 0.2279
Brugia malayi steroid hormone receptor 0.002 0.0061 0.0159
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0168
Brugia malayi Cathepsin L-like precursor 0.0019 0.0052 0.0132
Echinococcus granulosus cathepsin l1 0.0013 0.0009 0.0003
Schistosoma mansoni hypothetical protein 0.0047 0.0244 0.0241
Trichomonas vaginalis penicillin-binding protein, putative 0.0083 0.0488 0.1227
Loa Loa (eye worm) hypothetical protein 0.0034 0.0152 0.0433
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0023 0.008 0.018
Schistosoma mansoni hypothetical protein 0.0695 0.4673 0.4671
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Onchocerca volvulus 0.002 0.0061 0.0151
Trichomonas vaginalis D-aminoacylase, putative 0.0083 0.0488 0.1227
Loa Loa (eye worm) cysteine protease 0.0019 0.0052 0.0142
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.0208 1
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0144 0.0909 0.3305
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0018
Plasmodium vivax thioredoxin reductase, putative 0.0081 0.0474 0.9722
Schistosoma mansoni ran 0.0025 0.0092 0.0089
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0584 0.3909 1
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0111 0.0262
Schistosoma mansoni cpg binding protein 0.0057 0.0314 0.0311
Leishmania major trypanothione reductase 0.0081 0.0474 0.1568
Mycobacterium tuberculosis Conserved protein 0.0083 0.0488 0.1182
Schistosoma mansoni hypothetical protein 0.0036 0.017 0.0167
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Leishmania major heat shock protein 83-1 0.0023 0.008 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Entamoeba histolytica DNA topoisomerase II, putative 0.0023 0.008 0.0203
Trypanosoma cruzi heat shock protein 85, putative 0.0023 0.008 0.0279
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0488 1
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0064 0.0363 0.1034
Leishmania major GTP-binding protein, putative 0.0025 0.0092 0.0148
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0061 0.0055
Echinococcus multilocularis snurportin 1 0.0359 0.2376 0.2371
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0172 0.0617
Loa Loa (eye worm) beta-lactamase 0.0083 0.0488 0.1405
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.002 0.0014
Schistosoma mansoni gabp alpha 0.0084 0.05 0.0497
Loa Loa (eye worm) RecQ helicase 0.0023 0.0081 0.0225
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0083 0.0488 0.0485
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0111 0.0262
Brugia malayi Cathepsin L-like precursor 0.0019 0.0052 0.0132
Brugia malayi nuclear hormone receptor 0.002 0.0061 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0052 0.011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0172 0.0418
Loa Loa (eye worm) hypothetical protein 0.0114 0.0703 0.2029
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0006
Schistosoma mansoni single-minded 0.0028 0.0111 0.0108
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0172 0.0617

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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