Detailed information for compound 552080

Basic information

Technical information
  • TDR Targets ID: 552080
  • Name: 2-[(E)-non-1-en-3,5,7-triynyl]tetrahydropyran -3-ol
  • MW: 214.26 | Formula: C14H14O2
  • H donors: 1 H acceptors: 1 LogP: 2.04 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC#CC#CC#C/C=C/C1OCCCC1O
  • InChi: 1S/C14H14O2/c1-2-3-4-5-6-7-8-11-14-13(15)10-9-12-16-14/h8,11,13-15H,9-10,12H2,1H3/b11-8+
  • InChiKey: WFJPISZWZQHNLX-DHZHZOJOSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(E)-non-1-en-3,5,7-triynyl]-3-tetrahydropyranol
  • 2-[(E)-non-1-en-3,5,7-triynyl]oxan-3-ol
  • ichthyothereol
  • 20110-36-5
  • 20110-23-0
  • C13687
  • Cunaniol
  • 2S-Tetrahydro-2alpha(E)-(1-nonene-3,5,7-triynyl)-2H-pyran-3beta-ol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Schistosoma mansoni hypothetical protein 0.0111 0.0417 0.0474
Schistosoma mansoni hypothetical protein 0.0097 0.0363 0.0412
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0041 0.0086
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.0304
Schistosoma mansoni fatty acid binding protein 0.0301 0.1205 0.137
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0107 0.0107
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0203 0.023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0045 0.0051
Entamoeba histolytica hypothetical protein 0.0111 0.0417 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0111 1
Schistosoma mansoni fatty acid binding protein 0.0301 0.1205 0.137
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.001
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0203 0.5769
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0111 0.0315
Trypanosoma brucei glucosidase, putative 0.0036 0.0107 0.9666
Schistosoma mansoni hypothetical protein 0.0097 0.0363 0.0412
Treponema pallidum ATP-dependent DNA helicase 0.001 0.0001 0.5
Brugia malayi amine oxidase, flavin-containing family protein 0.0021 0.0045 0.0098
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.003 0.0034
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0363 0.0788
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.003 0.003
Schistosoma mansoni thyroid hormone receptor 0.002 0.0045 0.0051
Schistosoma mansoni microtubule-associated protein tau 0.2138 0.8794 1
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0417 0.0474
Loa Loa (eye worm) RecQ helicase 0.002 0.0041 0.0089
Brugia malayi nuclear receptor NHR-88 0.002 0.0045 0.0097
Brugia malayi Pre-SET motif family protein 0.0094 0.035 0.0761
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0204 0.0231
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0045 0.0051
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0003
Onchocerca volvulus 0.0749 0.3054 1
Echinococcus multilocularis fatty acid binding protein FABP2 0.0301 0.1205 0.1205
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0045 0.0051
Echinococcus multilocularis zinc finger protein 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0098
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0045 0.3999
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0045 0.0045
Leishmania major hypothetical protein, conserved 0.0015 0.0022 0.0402
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0107 0.0304
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0111 0.0585
Schistosoma mansoni bromodomain containing protein 0.0062 0.0218 0.0248
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0095 1
Brugia malayi Bromodomain containing protein 0.0074 0.0266 0.0578
Entamoeba histolytica hypothetical protein 0.0111 0.0417 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0624 0.0624
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0308 0.1232 0.2679
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0045 0.0097
Echinococcus granulosus GPCR family 2 0.0097 0.0363 0.0412
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0045 0.0097
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0204 0.0204
Echinococcus multilocularis GPCR, family 2 0.0097 0.0363 0.0363
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0203 1
Schistosoma mansoni zinc finger protein 0.0019 0.004 0.0045
Loa Loa (eye worm) hypothetical protein 0.007 0.0248 0.054
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0045 0.0097
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0045 0.0146
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0015 0.0033
Echinococcus multilocularis bloom syndrome protein 0.002 0.0041 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0111 0.042 0.0477
Schistosoma mansoni alpha-glucosidase 0.0138 0.0531 0.0604
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0045 0.0097
Brugia malayi steroid hormone receptor 0.002 0.0045 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0363 0.0363
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0624 0.0709
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0045 0.0097
Echinococcus multilocularis microtubule associated protein 2 0.2138 0.8794 0.8794
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0045 0.0097
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0111 0.5098
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0045 0.0045
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0045 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0045 0.0097
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0038 0.0117 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0045 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0045 0.0097
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0343 0.0343
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0461 0.1003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0658 0.2678 0.5823
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0045 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0045 0.0097
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0015 0.0022 0.0026
Echinococcus granulosus geminin 0.0167 0.0651 0.074
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0107 0.0233
Chlamydia trachomatis protoporphyrinogen oxidase 0.0021 0.0045 0.5
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0044 0.0096
Echinococcus granulosus microtubule associated protein 2 0.2138 0.8794 1
Entamoeba histolytica hypothetical protein 0.0111 0.0417 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0045 0.3999
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0111 0.0315
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0045 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0107 0.9708
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.035 0.0398
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0111 0.042 0.0477
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0045 0.0045
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0107 0.255
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0041 0.0086
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0045 0.0051
Brugia malayi latrophilin 2 splice variant baaae 0.021 0.083 0.1804
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0111 0.3133
Echinococcus granulosus FTZ F1 alpha 0.002 0.0045 0.0051
Loa Loa (eye worm) hypothetical protein 0.0042 0.0134 0.0291
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0107 0.4928
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0045 0.0097
Schistosoma mansoni coup transcription factor 0.002 0.0045 0.0051
Schistosoma mansoni nuclear hormone receptor 0.002 0.0045 0.0051
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0107 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0089
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0045 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0203 0.1405
Echinococcus granulosus fatty acid binding protein FABP2 0.0301 0.1205 0.137
Brugia malayi Pre-SET motif family protein 0.0658 0.2678 0.5823
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0343 0.0745
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0203 0.023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0343 0.039
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0021 0.0045 0.1253
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0045 0.0051
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0111 0.0315
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.003 0.0034
Echinococcus multilocularis protoporphyrinogen oxidase 0.0021 0.0045 0.0045
Schistosoma mansoni zinc finger protein 0.0015 0.0022 0.0026
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0041 0.0041
Brugia malayi MH2 domain containing protein 0.0121 0.0461 0.1003
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0041 0.0047
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0111 0.5
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0292 0.1166 1
Brugia malayi Bromodomain containing protein 0.0038 0.0116 0.0253
Echinococcus granulosus fatty acid binding protein, adipocyte 0.0132 0.0505 0.0575
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0045 0.0051
Brugia malayi hypothetical protein 0.0021 0.0045 0.0098
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0021 0.0045 0.0051
Leishmania major UDP-galactopyranose mutase 0.0021 0.0045 0.1603
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0111 0.0111
Echinococcus granulosus bloom syndrome protein 0.002 0.0041 0.0047
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0363 0.0788
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0111 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0461 0.1003
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0041 0.5
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.035 0.035
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0203 0.023
Brugia malayi hypothetical protein 0.0011 0.0005 0.001
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0052 0.0059
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0045 0.0051
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0045 0.0051
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0045 0.0045
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0045 0.0051
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0041 0.272
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0045 0.0045
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0292 0.1166 1
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0021 0.0045 0.1253
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0363 0.0412
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0015 0.0049
Schistosoma mansoni amine oxidase 0.0021 0.0045 0.0051
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0021 0.0045 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0098
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0045 0.0051
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0045 0.0051
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.1938
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.0304
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0005 0.0005
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0045 0.0051
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0107 0.255
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0274
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.1137
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0045 0.0097
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0045 0.0097
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0045 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0343 0.039
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0021 0.0045 0.1253
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.035 0.0398
Onchocerca volvulus 0.0094 0.035 0.1146
Schistosoma mansoni alpha-glucosidase 0.0138 0.0531 0.0604
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0308 0.1232 0.2679
Brugia malayi hypothetical protein 0.0111 0.0417 0.0907
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0107 0.0304
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0045 0.0097
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.0089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0343 0.039
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0111 0.0126
Schistosoma mansoni hypothetical protein 0.021 0.083 0.0944
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0015 0.1248
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0041 0.0041
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0107 0.0304
Echinococcus multilocularis fatty acid binding protein FABP2 0.0132 0.0505 0.0505
Plasmodium vivax SET domain protein, putative 0.0094 0.035 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0203 0.0203
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0041 0.0089
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.0304
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.003 0.0034
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.1938
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0041 0.0047
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0015 0.0328
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0343 0.039
Echinococcus granulosus histone lysine methyltransferase setb 0.0111 0.042 0.0477
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0343 0.0745
Schistosoma mansoni amine oxidase 0.0021 0.0045 0.0051
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0045 0.0051
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0095 0.0481
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0343 0.039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0033
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0417 0.0474
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0107 0.0122
Schistosoma mansoni DNA helicase recq5 0.002 0.0041 0.0047
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0001 0.0002
Brugia malayi SWIRM domain containing protein 0.0021 0.0045 0.0098
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0111 0.042 0.042
Schistosoma mansoni inositol monophosphatase 0.0036 0.0111 0.0126
Schistosoma mansoni hypothetical protein 0.0097 0.0363 0.0412
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0203 0.1405
Brugia malayi hypothetical protein 0.0011 0.0005 0.001
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0041 0.3629
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0203 0.1405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0098
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0107 0.0304
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0032 0.007
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0045 1
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0045 0.1253
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0045 0.1253
Schistosoma mansoni hypothetical protein 0.0167 0.0651 0.074
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0098
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0045 0.0051
Schistosoma mansoni hypothetical protein 0.002 0.0044 0.005
Brugia malayi nuclear hormone receptor 0.002 0.0045 0.0097
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0041 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.0304
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0045 0.0051
Plasmodium falciparum protoporphyrinogen oxidase 0.0021 0.0045 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0343 0.0343
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.1123 0.46 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0045 0.0045
Entamoeba histolytica recQ family helicase, putative 0.002 0.0041 0.0953
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0308 0.1232 0.2679
Schistosoma mansoni alpha glucosidase 0.0036 0.0107 0.0122
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0363 0.0363
Schistosoma mansoni DNA helicase recq1 0.002 0.0041 0.0047
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0203 0.152
Trypanosoma brucei ISWI complex protein 0.0015 0.0022 0.0788
Echinococcus multilocularis fatty acid binding protein FABP2 0.0301 0.1205 0.1205
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0045 0.0097
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0111 0.2626
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0107 0.0233
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0271 0.1081 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0097 0.0363 0.0788
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0045 0.1253
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0107 0.9708
Loa Loa (eye worm) hypothetical protein 0.021 0.083 0.1804
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0045 0.0097
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0045 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0098
Onchocerca volvulus 0.0021 0.0045 0.0147
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.001
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0005 0.001
Echinococcus granulosus fatty acid binding protein FABP2 0.0132 0.0505 0.0575
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0005 0.001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0308 0.1232 0.2679
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0107 0.3041
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.0304
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0045 0.0045
Trichomonas vaginalis set domain proteins, putative 0.0749 0.3054 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0015 0.1248
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0045 0.0045
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.1123 0.46 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0624 0.1356
Loa Loa (eye worm) inositol-1 0.0036 0.0111 0.024
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0363 0.0412
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0052 0.0052
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0624 0.1356
Brugia malayi Inositol-1 0.0036 0.0111 0.024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0045 0.0051
Brugia malayi nuclear receptor RXR 0.0011 0.0005 0.001
Entamoeba histolytica hypothetical protein 0.0111 0.0417 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0417 0.0417
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0045 0.0097
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0052 0.0059
Loa Loa (eye worm) hypothetical protein 0.0111 0.042 0.0912
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.0089
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0045 0.0146
Onchocerca volvulus 0.002 0.0045 0.0146
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0363 0.0788
Schistosoma mansoni inositol monophosphatase 0.0036 0.0111 0.0126
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0041 0.1387
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0336 0.0382
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0107 0.0121
Brugia malayi ecdysteroid receptor 0.002 0.0045 0.0097
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0093 0.0344 0.1126
Schistosoma mansoni thyroid hormone receptor 0.002 0.0045 0.0051
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0045 0.0045
Echinococcus granulosus fatty acid binding protein FABP2 0.0301 0.1205 0.137
Echinococcus multilocularis 0.0021 0.0045 0.0045
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0041 0.0086
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0041 0.1137
Schistosoma mansoni hypothetical protein 0.0167 0.0651 0.074
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.035 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0097
Echinococcus multilocularis geminin 0.0167 0.0651 0.0651
Echinococcus granulosus zinc finger protein 0.0019 0.004 0.0045
Schistosoma mansoni hypothetical protein 0.0097 0.0363 0.0412
Brugia malayi PHD-finger family protein 0.0025 0.0062 0.0134
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0111 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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