Detailed information for compound 555939

Basic information

Technical information
  • TDR Targets ID: 555939
  • Name: N-benzhydryl-N-ethyl-ethanamine
  • MW: 239.355 | Formula: C17H21N
  • H donors: 0 H acceptors: 0 LogP: 4.19 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(C(c1ccccc1)c1ccccc1)CC
  • InChi: 1S/C17H21N/c1-3-18(4-2)17(15-11-7-5-8-12-15)16-13-9-6-10-14-16/h5-14,17H,3-4H2,1-2H3
  • InChiKey: JFNHRCHVABSSDJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-benzhydryl-N-ethylethanamine
  • benzhydryl(diethyl)amine
  • N-[di(phenyl)methyl]-N-ethylethanamine
  • N-[di(phenyl)methyl]-N-ethyl-ethanamine
  • di(phenyl)methyl-diethyl-amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.009 0.0427
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0077 0.0237 0.059
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.011 0.0229
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0019 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0033 0.0081
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0028 0.0479
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0125 0.0409 0.2303
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0118 0.0385 0.2165
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0287 0.027
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0049 0.0137 0.0705
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0028 0.0069
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0128 0.0653
Brugia malayi Muscleblind-like protein 0.0149 0.0496 0.1235
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.009 0.0073
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0019 0.0063
Onchocerca volvulus Huntingtin homolog 0.0246 0.0842 0.2034
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0019 0.0036
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0063 0.1533
Loa Loa (eye worm) hypothetical protein 0.0125 0.0409 0.1019
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0488 0.1713 1
Echinococcus granulosus small conductance calcium activated potassium 0.0142 0.0472 0.0455
Loa Loa (eye worm) hypothetical protein 0.0246 0.0842 0.2099
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0042 0.0112 0.056
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0033 0.0015
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0033 0.0015
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1604 0.5718 0.571
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0137 0.1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0137 0.0341
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0296 0.0279
Brugia malayi glutathione reductase 0.0047 0.0128 0.0319
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.009 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0033 0.0081
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.009 0.0073
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0233 0.572
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0137 0.22
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0028 1
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.009 0.042
Loa Loa (eye worm) hypothetical protein 0.0048 0.0134 0.0335
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0049 0.0137 0.0697
Onchocerca volvulus 0.0049 0.0137 0.0262
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0237 0.022
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0088
Schistosoma mansoni glycogen phosphorylase 0.113 0.4014 0.4004
Onchocerca volvulus 0.0036 0.009 0.0143
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0017 0.0415
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0028 0.001
Schistosoma mansoni thyroid hormone receptor 0.002 0.0033 0.0015
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0033 0.0081
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0108 0.2637
Echinococcus multilocularis small conductance calcium activated potassium 0.0142 0.0472 0.0455
Mycobacterium ulcerans hypothetical protein 0.0036 0.009 0.042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0033 0.0081
Toxoplasma gondii ABC1 family protein 0.0036 0.009 0.3367
Entamoeba histolytica hypothetical protein 0.0044 0.0118 0.0225
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0063 0.0157
Brugia malayi beta-lactamase family protein 0.0036 0.009 0.0224
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0049 0.0137 0.0705
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0028 0.0022
Mycobacterium ulcerans beta-lactamase 0.0036 0.009 0.042
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0269
Brugia malayi jmjC domain containing protein 0.0036 0.009 0.0225
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0137 0.5556
Brugia malayi nuclear receptor NHR-88 0.002 0.0033 0.0081
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0033 0.0015
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0049 0.0137 0.0705
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0134 0.0335
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0108 0.0269
Echinococcus granulosus GPCR family 2 0.0048 0.0134 0.0117
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0028 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0049 0.0137 0.0705
Mycobacterium tuberculosis Possible penicillin-binding protein 0.023 0.0785 0.4529
Toxoplasma gondii thioredoxin reductase 0.0047 0.0128 0.5146
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0033 0.0081
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0044 0.0118 0.01
Trypanosoma cruzi ion transport protein, putative 0.0121 0.0394 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.009 0.0224
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0033 0.0015
Echinococcus multilocularis tar DNA binding protein 0.0077 0.0237 0.022
Onchocerca volvulus 0.0036 0.009 0.0143
Brugia malayi beta-lactamase family protein 0.0036 0.009 0.0224
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0033 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0966 0.2371
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0017 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0036
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0167 0.0561 0.3199
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0033 0.0081
Mycobacterium tuberculosis Conserved protein 0.0036 0.009 0.0427
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.009 0.0225
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.009 0.0427
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0309 0.0706
Echinococcus multilocularis cpg binding protein 0.003 0.0069 0.0052
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0063 0.2123
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.009 0.0178
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.009 0.0073
Schistosoma mansoni hypothetical protein 0.0859 0.3042 0.303
Onchocerca volvulus Huntingtin homolog 0.0246 0.0842 0.2034
Trypanosoma cruzi ion transport protein, putative 0.0121 0.0394 1
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0033 0.0081
Echinococcus multilocularis glycogen phosphorylase 0.113 0.4014 0.4004
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0496 0.0479
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0049 0.0137 0.0341
Mycobacterium tuberculosis Probable reductase 0.0106 0.0343 0.1917
Brugia malayi Thioredoxin reductase 0.0047 0.0128 0.0319
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0343 0.1917
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0137 0.0705
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0033 0.0081
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0309 0.0292
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0088
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0033 0.0081
Schistosoma mansoni coup transcription factor 0.002 0.0033 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Schistosoma mansoni hypothetical protein 0.0048 0.0134 0.0117
Schistosoma mansoni ap endonuclease 0.0019 0.0028 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0033 0.0015
Schistosoma mansoni hypothetical protein 0.0034 0.0083 0.0065
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0003 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0172 0.0428
Brugia malayi RNA binding protein 0.0077 0.0237 0.059
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0287 0.0714
Toxoplasma gondii LsmAD domain-containing protein 0.0076 0.0233 1
Brugia malayi hypothetical protein 0.0037 0.0094 0.0234
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0028 0.0069
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0224
Entamoeba histolytica glycogen phosphorylase, putative 0.0488 0.1713 0.4228
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0049 0.0137 0.5556
Schistosoma mansoni glycogen phosphorylase 0.113 0.4014 0.4004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0287 0.027
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0343 0.1917
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0019 0.0448
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0137 0.0341
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0287 0.027
Onchocerca volvulus 0.0028 0.0063 0.0076
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0028 0.0022
Loa Loa (eye worm) hypothetical protein 0.0097 0.0309 0.077
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0134 0.0117
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0224
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0036
Echinococcus multilocularis microtubule associated protein 2 0.2798 1 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0224
Schistosoma mansoni transcription factor LCR-F1 0.0044 0.0118 0.01
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0049 0.0137 0.334
Schistosoma mansoni microtubule-associated protein tau 0.2798 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0233 0.572
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0033 0.0015
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0049 0.0137 0.5556
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0033 0.0015
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0049 0.0137 0.0697
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0343 0.5366
Loa Loa (eye worm) hypothetical protein 0.0105 0.0336 0.0837
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0134 0.0335
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.009 0.0178
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0125 0.0409 0.0977
Brugia malayi nuclear hormone receptor 0.002 0.0033 0.0081
Plasmodium falciparum glutathione reductase 0.0016 0.0019 0.0448
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0028 0.0061
Trichomonas vaginalis glycogen phosphorylase, putative 0.113 0.4014 1
Echinococcus granulosus dnaJ subfamily B 0.0406 0.1417 0.1402
Schistosoma mansoni calcium-activated potassium channel 0.0142 0.0472 0.0455
Loa Loa (eye worm) RNA binding protein 0.0077 0.0237 0.059
Schistosoma mansoni hypothetical protein 0.0048 0.0134 0.0117
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0049 0.0137 0.0705
Schistosoma mansoni acetyl-CoA synthetase 0.0049 0.0137 0.012
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0049 0.0137 0.0697
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0134 0.0335
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0966 0.2371
Brugia malayi hypothetical protein 0.0246 0.0842 0.2099
Entamoeba histolytica acyl-CoA synthetase, putative 0.0167 0.0561 0.1337
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0459 0.0442
Brugia malayi AMP-binding enzyme family protein 0.0167 0.0561 0.1397
Loa Loa (eye worm) hypothetical protein 0.0125 0.0409 0.1019
Brugia malayi MH2 domain containing protein 0.0117 0.038 0.0946
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0063 0.0046
Toxoplasma gondii exonuclease III APE 0.0019 0.0028 0.0479
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.009 0.0427
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.011 0.0275
Mycobacterium ulcerans acyl-CoA synthetase 0.0167 0.0561 0.3199
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0136 0.0339
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.009 0.0073
Schistosoma mansoni hypothetical protein 0.0048 0.0134 0.0117
Loa Loa (eye worm) glutathione reductase 0.0047 0.0128 0.0319
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.009 0.0178
Entamoeba histolytica glycogen phosphorylase, putative 0.113 0.4014 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0044 0.0118 0.01
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0063 0.0046
Mycobacterium ulcerans hypothetical protein 0.0167 0.0561 0.3199
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.009 0.1926
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.009 0.1926
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0033 0.0015
Echinococcus multilocularis expressed conserved protein 0.0091 0.0288 0.0271
Schistosoma mansoni glycogen phosphorylase 0.0488 0.1713 0.1699
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0033 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0083 0.0065
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.062 0.1506
Schistosoma mansoni cpg binding protein 0.0028 0.0063 0.0046
Brugia malayi hypothetical protein 0.0049 0.0136 0.0339
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0137 0.0705
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0134 0.0117
Leishmania major hypothetical protein, conserved 0.0036 0.009 0.1333
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0019 0.0063
Loa Loa (eye worm) hypothetical protein 0.0167 0.0561 0.1397
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0227 0.021
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0049 0.0137 0.1
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0233 0.568
Onchocerca volvulus 0.0036 0.009 0.0143
Loa Loa (eye worm) oxidoreductase 0.0049 0.0137 0.0341
Trichomonas vaginalis esterase, putative 0.0036 0.009 0.0178
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0049 0.0137 0.0705
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0237 0.022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.009 0.0073
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0108 0.0091
Giardia lamblia Glycogen phosphorylase 0.113 0.4014 1
Brugia malayi ecdysteroid receptor 0.002 0.0033 0.0081
Entamoeba histolytica glycogen phosphorylase, putative 0.113 0.4014 1
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0137 0.0341
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0336 0.0837
Brugia malayi jmjC domain containing protein 0.0093 0.0296 0.0737
Mycobacterium ulcerans acyl-CoA synthetase 0.0167 0.0561 0.3199
Echinococcus granulosus cpg binding protein 0.003 0.0069 0.0052
Brugia malayi CHE-14 protein 0.0042 0.011 0.0275
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0385 0.2168
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0224
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0028 0.019
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0224
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0049 0.0137 0.1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0036
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0128 0.0319
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0966 0.2371
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0025 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0287 0.027
Entamoeba histolytica hypothetical protein 0.0044 0.0118 0.0225
Toxoplasma gondii propionate-CoA ligase 0.0049 0.0137 0.5556
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0028 0.0667
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0385 0.2168
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.009 0.0178
Onchocerca volvulus 0.0049 0.0137 0.0262
Echinococcus granulosus FTZ F1 alpha 0.002 0.0033 0.0015
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.011 0.0093
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0019 0.0448
Loa Loa (eye worm) hypothetical protein 0.0125 0.0409 0.1019
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0128 0.0111
Leishmania major acetyl-CoA synthetase, putative 0.0049 0.0137 0.22
Loa Loa (eye worm) hypothetical protein 0.0076 0.0233 0.0579
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0125 0.0409 0.231
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0083 0.0065
Schistosoma mansoni hypothetical protein 0.0859 0.3042 0.303
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0033 0.0081
Entamoeba histolytica hypothetical protein 0.0044 0.0118 0.0225
Brugia malayi TAR-binding protein 0.0077 0.0237 0.059
Trypanosoma brucei PAB1-binding protein , putative 0.0076 0.0233 1
Echinococcus multilocularis GPCR, family 2 0.0048 0.0134 0.0117
Leishmania major trypanothione reductase 0.0047 0.0128 0.2038
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0966 0.2371
Schistosoma mansoni hypothetical protein 0.0041 0.0108 0.0091
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0028 0.0053
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0033 0.0015
Loa Loa (eye worm) TAR-binding protein 0.0077 0.0237 0.059
Echinococcus granulosus tar DNA binding protein 0.0077 0.0237 0.022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0033 0.0015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.0509 0.1269
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0134 0.0117
Brugia malayi hypothetical protein 0.0037 0.0094 0.0234
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0088
Brugia malayi isocitrate dehydrogenase 0.0016 0.0017 0.0043
Loa Loa (eye worm) hypothetical protein 0.0149 0.0496 0.1235
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0359
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0167 0.0561 0.3199
Onchocerca volvulus Glycogen phosphorylase homolog 0.113 0.4014 1
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0033 0.0081
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0966 0.2371
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0128 0.0111
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0154 0.637
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0385 0.2168
Echinococcus granulosus jumonji domain containing protein 0.004 0.0103 0.0086
Echinococcus granulosus Glycosyl transferase family 35 0.113 0.4014 0.4004
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0033 0.0015
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0309 0.077
Echinococcus multilocularis protein dispatched 1 0.0048 0.0131 0.0114
Echinococcus granulosus geminin 0.0859 0.3042 0.303
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0033 0.0081
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0137 0.0697
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.038 0.0946
Brugia malayi carbohydrate phosphorylase 0.113 0.4014 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0033 0.0081
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0033 0.0015
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.011 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.062 0.1506
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.1417 0.1402
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0167 0.0561 0.3204
Echinococcus granulosus muscleblind protein 0.0149 0.0496 0.0479
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0033 0.0015
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.009 0.0427
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0028 0.0274
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0033 0.0081
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0137 0.3178
Schistosoma mansoni cpg binding protein 0.003 0.0069 0.0052
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.009 0.0178
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0019 0.0063
Onchocerca volvulus 0.0049 0.0137 0.0262
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0385 0.6271
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0049 0.0137 0.0274
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.062 0.1506
Schistosoma mansoni hypothetical protein 0.0029 0.0063 0.0046
Brugia malayi RNA recognition motif domain containing protein 0.0077 0.0237 0.059
Mycobacterium ulcerans acetyl-CoA synthetase 0.0049 0.0137 0.0697
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0343 0.1917
Brugia malayi steroid hormone receptor 0.002 0.0033 0.0081
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0137 0.0341
Schistosoma mansoni hypothetical protein 0.0406 0.1417 0.1402
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0063 0.0046
Entamoeba histolytica glycogen phosphorylase, putative 0.0488 0.1713 0.4228
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.038 0.0946
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0019 0.0047
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0019 0.0063
Onchocerca volvulus 0.0049 0.0137 0.0262
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0128 0.3125
Schistosoma mansoni ap endonuclease 0.0019 0.0028 0.001
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0049 0.0137 0.012
Echinococcus multilocularis protein patched 0.0042 0.011 0.0093
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.009 0.042
Loa Loa (eye worm) hypothetical protein 0.0246 0.0842 0.2099
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0309 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0033 0.0081
Entamoeba histolytica acyl-CoA synthetase, putative 0.0167 0.0561 0.1337
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0033 0.0015
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0049 0.0137 0.0341
Echinococcus granulosus Protein patched homolog 1 0.0042 0.011 0.0093
Echinococcus multilocularis peregrin 0.0029 0.0063 0.0046
Plasmodium falciparum acyl-CoA synthetase 0.0125 0.0409 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0125 0.0409 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0033 0.0081
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0017 0.0415
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0224
Echinococcus granulosus glycogen phosphorylase 0.113 0.4014 0.4004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.009 0.0427
Onchocerca volvulus Alhambra homolog 0.0029 0.0063 0.0076
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0049 0.0137 0.3178
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0036
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0103 0.0086
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0019 0.0036
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0033 0.0015
Trichomonas vaginalis antibiotic synthetase, putative 0.0049 0.0137 0.0296
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.0509 0.1269
Plasmodium falciparum phd finger protein, putative 0.0029 0.0063 0.1533
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0287 0.027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0287 0.027
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0134 0.0117
Plasmodium vivax hypothetical protein, conserved 0.0036 0.009 0.2188
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0033 0.0015
Mycobacterium tuberculosis Conserved protein 0.0036 0.009 0.0427
Brugia malayi CXXC zinc finger family protein 0.0028 0.0063 0.0157
Giardia lamblia PHD finger protein 15 0.0029 0.0063 0.0111
Schistosoma mansoni patched 1 0.0042 0.011 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.062 0.1506
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0033 0.0015
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.009 0.0073
Entamoeba histolytica glycogenphosphorylase, putative 0.0488 0.1713 0.4228
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0118 0.0385 0.2165
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0167 0.0561 0.3204
Mycobacterium tuberculosis Conserved protein 0.0036 0.009 0.0427
Trichomonas vaginalis glycogen phosphorylase, putative 0.113 0.4014 1
Brugia malayi hypothetical protein 0.0076 0.0233 0.0579
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0033 0.0015
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0033 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0028 0.0274
Loa Loa (eye worm) hypothetical protein 0.0029 0.0063 0.0157
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0049 0.0137 0.0697
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0028 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0118 0.0385 0.2165
Trypanosoma brucei trypanothione reductase 0.0047 0.0128 0.5146
Trichomonas vaginalis antibiotic synthetase, putative 0.0049 0.0137 0.0296
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0108 0.0269
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0063 0.2123
Mycobacterium ulcerans acyl-CoA synthetase 0.0167 0.0561 0.3199
Onchocerca volvulus Glucosylceramidase homolog 0.0184 0.062 0.1476
Schistosoma mansoni thyroid hormone receptor 0.002 0.0033 0.0015
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0003 0.0008
Echinococcus granulosus expressed conserved protein 0.0091 0.0288 0.0271
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0033 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0033 0.0081
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0128 0.2944
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0028 0.0667
Brugia malayi Bromodomain containing protein 0.0029 0.0063 0.0157
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0237 0.022
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0343 0.1917
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0287 0.0714
Plasmodium falciparum glutathione reductase 0.0047 0.0128 0.3125
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0033 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0019 0.0063
Echinococcus granulosus peregrin 0.0029 0.0063 0.0046
Loa Loa (eye worm) hypothetical protein 0.0153 0.0509 0.1269
Leishmania major 4-coumarate:coa ligase-like protein 0.0167 0.0561 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0033 0.0081
Loa Loa (eye worm) hypothetical protein 0.0071 0.0217 0.0541
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0178 0.016
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0019 0.0001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0019 0.0063
Brugia malayi hypothetical protein 0.0044 0.0118 0.0293
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0049 0.0137 0.0341
Brugia malayi PHD-finger family protein 0.0029 0.0063 0.0157
Leishmania major ion transport protein-like protein 0.0121 0.0394 0.6923
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0966 0.2371
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0167 0.0561 0.3199
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0033 0.0081
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.062 0.1506
Brugia malayi beta-lactamase 0.0036 0.009 0.0224
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0028 0.001
Plasmodium vivax ataxin-2 like protein, putative 0.0076 0.0233 0.568
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.009 0.0224
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0049 0.0137 0.3178
Echinococcus multilocularis muscleblind protein 0.0149 0.0496 0.0479
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.028 0.0966 0.2407
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.062 0.1506
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0049 0.0137 0.012
Plasmodium vivax glutathione reductase, putative 0.0047 0.0128 0.3125
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0167 0.0561 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0033 0.0015
Schistosoma mansoni hypothetical protein 0.0044 0.0118 0.01
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0118 0.0385 0.2165
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.009 0.0073
Loa Loa (eye worm) hypothetical protein 0.0049 0.0137 0.0341
Schistosoma mansoni calcium-activated potassium channel 0.0136 0.0447 0.043
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0137 0.0341
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.009 0.3367
Leishmania major acetyl-CoA synthetase, putative 0.0049 0.0137 0.22
Brugia malayi AMP-binding enzyme family protein 0.0167 0.0561 0.1397
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0025
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0049 0.0137 0.3178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0033 0.0081
Loa Loa (eye worm) hypothetical protein 0.0064 0.0191 0.0475
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0488 0.1713 1
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0108 0.0269
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0081
Loa Loa (eye worm) hypothetical protein 0.0125 0.0409 0.1019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0033 0.0081
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0033 0.0081
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.009 0.0427
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.062 0.1506
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0049 0.0137 0.0697
Schistosoma mansoni hypothetical protein 0.0142 0.0472 0.0455
Loa Loa (eye worm) beta-lactamase 0.0036 0.009 0.0224
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0237 0.022
Leishmania major 4-coumarate:coa ligase-like protein 0.0167 0.0561 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0167 0.0561 0.1337
Echinococcus granulosus glycogen phosphorylase 0.113 0.4014 0.4004
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0137 0.0705
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0033 0.0015
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0296 0.0279
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0041 0.0108 0.422
Echinococcus multilocularis Glycosyl transferase, family 35 0.113 0.4014 0.4004
Plasmodium falciparum thioredoxin reductase 0.0016 0.0019 0.0448
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0085 0.0067
Plasmodium vivax acetyl-CoA synthetase, putative 0.0049 0.0137 0.334
Brugia malayi AMP-binding enzyme family protein 0.0167 0.0561 0.1397
Plasmodium falciparum thioredoxin reductase 0.0047 0.0128 0.3125
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0108 0.2637
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0315 0.0298
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0459 0.0442
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0019 0.0448
Leishmania major hypothetical protein, conserved 0.0076 0.0233 0.3959
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0167 0.0561 0.1397
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0287 0.027
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0049 0.0137 0.5556
Echinococcus multilocularis geminin 0.0859 0.3042 0.303
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0019 0.0001
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0049 0.0137 0.0705
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0049 0.0137 0.0697
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0019 0.0448
Loa Loa (eye worm) hypothetical protein 0.0125 0.0409 0.1019
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.0509 0.1269
Loa Loa (eye worm) hypothetical protein 0.0167 0.0561 0.1397
Loa Loa (eye worm) hypothetical protein 0.0142 0.0472 0.1176
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0233 0.568
Schistosoma mansoni hypothetical protein 0.0048 0.0134 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0656 0.1595
Schistosoma mansoni nuclear hormone receptor 0.002 0.0033 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0033 0.0015
Echinococcus multilocularis glycogen phosphorylase 0.113 0.4014 0.4004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0036
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0033 0.0015
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.028 0.0966 0.2407
Entamoeba histolytica hypothetical protein 0.0044 0.0118 0.0225
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0049 0.0137 0.0697
Loa Loa (eye worm) glycogen phosphorylase 0.113 0.4014 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0019 0.0025
Schistosoma mansoni cpg binding protein 0.003 0.0069 0.0052
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0343 0.1917
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0167 0.0561 0.3199
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0017 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0237 0.022
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0167 0.0561 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0033 0.0081
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0063 0.0157
Schistosoma mansoni hypothetical protein 0.0105 0.0336 0.0319
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0042 0.011 0.0275
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0049 0.0137 0.0341
Onchocerca volvulus 0.0167 0.0561 0.1326
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0137 0.0705
Mycobacterium ulcerans lipase LipD 0.0036 0.009 0.042
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0137 0.0697
Leishmania major 4-coumarate:coa ligase-like protein 0.0167 0.0561 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.0496 0.1235
Chlamydia trachomatis glycogen phosphorylase 0.113 0.4014 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0019 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0194 0.0656 0.1595

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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