Detailed information for compound 562667

Basic information

Technical information
  • TDR Targets ID: 562667
  • Name: (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-pentyl-6a ,7,10,10a-tetrahydrobenzo[c]chromene-9-carbox ylic acid
  • MW: 344.445 | Formula: C21H28O4
  • H donors: 2 H acceptors: 3 LogP: 5.06 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCc1cc(O)c2c(c1)OC([C@H]1[C@H]2CC(=CC1)C(=O)O)(C)C
  • InChi: 1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h8,10-11,15-16,22H,4-7,9,12H2,1-3H3,(H,23,24)/t15-,16-/m1/s1
  • InChiKey: OGXXAQFMAFTSRU-HZPDHXFCSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c][1]benzopyran-9-carboxylic acid
  • (6aR,10aR)-3-amyl-1-hydroxy-6,6-dimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromene-9-carboxylic acid
  • delta(6)-tetrahydrocannabinol-7-oic acid
  • 39690-06-7
  • 11-Nor-8-carboxy-thc
  • 11-Nor-delta(8)-tetrahydrocannabinol-9-carboxylic acid
  • 11-Nor-delta(8)-thc-cooh
  • 6H-Dibenzo(b,d)pyran-9-carboxylic acid, 6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-, (6aR-trans)-
  • delta(8)-Tetrahydrocannabinol-11-oic acid
  • delta(8)-Thc-11-oic acid
  • PDSP2_000216

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.1032 0.4529 0.5331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0642 0.2787 0.3266
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0146 0.0572 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1537 0.1785
Brugia malayi ion channel NompC 0.0146 0.0572 0.0656
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0082 0.0097
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0146 0.0572 0.0656
Echinococcus granulosus potassium voltage gated channel protein 0.0146 0.0572 0.0572
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0146 0.0572 0.0572
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0146 0.0572 0.0572
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0123 0.0471 0.0538
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus granulosus potassium voltage gated channel protein 0.0146 0.0572 0.0572
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0471 0.0538
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0642 0.2787 0.2787
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0042 0.0013
Brugia malayi Transient-receptor-potential like protein 0.0146 0.0572 0.0656
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0146 0.0572 0.0572
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0471 0.0471
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0362 0.1537 0.1798
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0146 0.0572 0.0572
Entamoeba histolytica hypothetical protein 0.0123 0.0471 0.0522
Giardia lamblia GTOR 0.1914 0.8469 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0082 0.0097
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0123 0.0471 0.0471
Schistosoma mansoni transient receptor potential channel 0.0146 0.0572 0.0675
Loa Loa (eye worm) hypothetical protein 0.0403 0.1721 0.2015
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0031 0.0031
Echinococcus multilocularis potassium voltage gated channel protein 0.0146 0.0572 0.0572
Schistosoma mansoni hypothetical protein 0.0956 0.4189 0.4946
Schistosoma mansoni two-pore calcium channel 0.0146 0.0572 0.0675
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0362 0.1537 0.1785
Schistosoma mansoni fkbp-rapamycin associated protein 0.0362 0.1537 0.1815
Brugia malayi FAT domain containing protein 0.028 0.117 0.1364
Trichomonas vaginalis PIKK family atypical protein kinase 0.1144 0.5028 0.5922
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0123 0.0471 1
Loa Loa (eye worm) voltage-gated potassium channel 0.0146 0.0572 0.0655
Trichomonas vaginalis PIKK family atypical protein kinase 0.1522 0.672 0.7927
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0146 0.0572 0.0656
Echinococcus granulosus shaker cognate 0.0146 0.0572 0.0572
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1914 0.8469 0.8469
Echinococcus multilocularis potassium voltage gated channel protein 0.0146 0.0572 0.0572
Plasmodium falciparum importin beta, putative 0.0034 0.007 0.0901
Entamoeba histolytica hypothetical protein 0.0042 0.0108 0.0091
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0146 0.0572 0.0572
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0146 0.0572 0.0675
Trichomonas vaginalis set domain proteins, putative 0.0278 0.1163 0.1341
Loa Loa (eye worm) hypothetical protein 0.0123 0.0471 0.0536
Schistosoma mansoni hypothetical protein 0.0146 0.0572 0.0675
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0146 0.0572 0.0675
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0471 0.0538
Trichomonas vaginalis PIKK family atypical protein kinase 0.1284 0.5654 0.6665
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0362 0.1537 0.1785
Echinococcus multilocularis serine protein kinase ATM 0.0362 0.1537 0.1537
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0146 0.0572 0.0572
Onchocerca volvulus 0.0123 0.0471 0.3603
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0123 0.0471 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0146 0.0572 0.0656
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0123 0.0471 0.0522
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0245 0.1012 0.1176
Echinococcus granulosus potassium voltage gated channel protein 0.0146 0.0572 0.0572
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0146 0.0572 0.0655
Trichomonas vaginalis PIKK family atypical protein kinase 0.1144 0.5028 0.5922
Echinococcus multilocularis ryanodine receptor 44f 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.1033 0.4536 0.5339
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Loa Loa (eye worm) hypothetical protein 0.0239 0.0985 0.1144
Loa Loa (eye worm) hypothetical protein 0.028 0.117 0.1363
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0146 0.0572 0.0656
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0123 0.0471 0.0557
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0146 0.0572 0.0572
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0239 0.0985 0.1131
Echinococcus multilocularis sodium leak channel non selective protein 0.0146 0.0572 0.0572
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0146 0.0572 0.0572
Echinococcus multilocularis importin subunit beta 1 0.0034 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.1914 0.8469 1
Echinococcus granulosus voltage gated potassium channel 0.0146 0.0572 0.0572
Entamoeba histolytica hypothetical protein 0.0123 0.0471 0.0522
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0795 0.3471 0.4077
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0146 0.0572 0.0572
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0123 0.0471 0.0522
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1914 0.8469 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0123 0.0471 0.0522
Echinococcus multilocularis voltage dependent calcium channel 0.0146 0.0572 0.0572
Echinococcus multilocularis transfer RNA-Gly 0.0146 0.0572 0.0572
Echinococcus granulosus transient receptor potential gamma protein 0.0146 0.0572 0.0572
Onchocerca volvulus 0.0123 0.0471 0.3603
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0471 0.0538
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0522
Entamoeba histolytica hypothetical protein 0.0362 0.1537 0.1785
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0146 0.0572 0.4533
Trichomonas vaginalis PIKK family atypical protein kinase 0.1634 0.7219 0.8519
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0123 0.0471 0.0522
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0642 0.2787 0.2787
Leishmania major hypothetical protein, unknown function 0.0146 0.0572 0.0543
Schistosoma mansoni hypothetical protein 0.036 0.1526 0.1802
Trichomonas vaginalis PIKK family atypical protein kinase 0.1144 0.5028 0.5922
Trichomonas vaginalis PIKK family atypical protein kinase 0.1522 0.672 0.7927
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0642 0.2787 0.3277
Trichomonas vaginalis conserved hypothetical protein 0.028 0.117 0.135
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0362 0.1537 0.1537
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0146 0.0572 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0239 0.0985 0.1131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0642 0.2787 0.3266
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0123 0.0471 0.0522
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0146 0.0572 0.0656
Trichomonas vaginalis PIKK family atypical protein kinase 0.1242 0.547 0.6446
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0123 0.0471 0.0471
Plasmodium vivax SET domain protein, putative 0.0036 0.0082 0.117
Toxoplasma gondii hypothetical protein 0.0146 0.0572 0.0867
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0146 0.0572 0.0675
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0123 0.0471 0.0471
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0123 0.0471 0.0471
Entamoeba histolytica hypothetical protein 0.0123 0.0471 0.0522
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0146 0.0572 0.0572
Toxoplasma gondii hypothetical protein 0.0146 0.0572 0.0867
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0123 0.0471 0.0522
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0522
Echinococcus granulosus potassium voltage gated channel protein 0.0146 0.0572 0.0572
Leishmania major phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0442
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus multilocularis cpg binding protein 0.0071 0.0237 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0514 0.2214 0.2587
Schistosoma mansoni transient receptor potential channel 0.0146 0.0572 0.0675
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0031 0.0015
Echinococcus granulosus potassium large conductance calcium activated 0.0146 0.0572 0.0572
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0123 0.0471 0.0557
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0123 0.0471 1
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.2257 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0082 0.0082
Echinococcus multilocularis transient receptor potential cation channel 0.0146 0.0572 0.0572
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0146 0.0572 0.0675
Onchocerca volvulus 0.0146 0.0572 0.4533
Trichomonas vaginalis PIKK family atypical protein kinase 0.1032 0.4529 0.5331
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0642 0.2787 0.3291
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0146 0.0572 0.0572
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0146 0.0572 0.0675
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0144 0.0561 0.0663
Echinococcus granulosus voltage dependent calcium channel 0.0146 0.0572 0.0572
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0471 0.0538
Echinococcus granulosus voltage dependent calcium channel 0.0146 0.0572 0.0572
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0108 0.0108
Brugia malayi voltage-dependent calcium channel 0.0146 0.0572 0.0656
Plasmodium vivax importin-beta 2, putative 0.0034 0.007 0.0901
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0146 0.0572 0.0572
Echinococcus granulosus sodium leak channel non selective protein 0.0146 0.0572 0.0572
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0471 0.0706
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0471 0.0706
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0123 0.0471 0.0471
Echinococcus granulosus transient receptor potential cation channel 0.0146 0.0572 0.0572
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.036 0.1526 0.1784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0642 0.2787 0.3266
Brugia malayi Cyclic-nucleotide gated cation channel 0.0146 0.0572 0.0656
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0146 0.0572 0.0675
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1914 0.8469 1
Echinococcus granulosus short transient receptor potential channel 6 0.0146 0.0572 0.0572
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.0572 0.0642
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Echinococcus granulosus hyperpolarization activated cyclic 0.0146 0.0572 0.0572
Entamoeba histolytica hypothetical protein 0.0042 0.0108 0.0091
Schistosoma mansoni importin beta-1 0.0034 0.007 0.0083
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0146 0.0572 0.0572
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0123 0.0471 1
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0471 0.0471
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni calcium-activated potassium channel 0.0146 0.0572 0.0675
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0123 0.0471 0.0522
Loa Loa (eye worm) voltage-gated potassium channel 0.0146 0.0572 0.0655
Echinococcus multilocularis short transient receptor potential channel 6 0.0146 0.0572 0.0572
Schistosoma mansoni hypothetical protein 0.0042 0.0108 0.0127
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.028 0.117 0.117
Leishmania major hypothetical protein, conserved 0.0123 0.0471 0.0442
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0146 0.0572 0.0572
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1914 0.8469 0.8464
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0108 0.0127
Schistosoma mansoni vesicular amine transporter 0.0146 0.0572 0.0675
Echinococcus multilocularis potassium voltage gated channel protein 0.0146 0.0572 0.0572
Echinococcus granulosus snurportin 1 0.036 0.1526 0.1526
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0123 0.0471 0.0522
Schistosoma mansoni voltage-gated ion channel 0.0146 0.0572 0.0675
Leishmania major phosphatidylinositol kinase, putative 0.0123 0.0471 0.0442
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0123 0.0471 0.0522
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0146 0.0572 0.0572
Schistosoma mansoni transient receptor potential channel 0.0146 0.0572 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0642 0.2787 0.3266
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0123 0.0471 0.0522
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0362 0.1537 0.1798
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0018 0.0018
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0123 0.0471 0.0557
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0146 0.0572 0.0656
Echinococcus multilocularis transient receptor potential gamma protein 0.0146 0.0572 0.0572
Echinococcus granulosus transient receptor potential cation channel 0.0146 0.0572 0.0572
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0146 0.0572 0.0572
Echinococcus granulosus cpg binding protein 0.0071 0.0237 0.0237
Schistosoma mansoni hypothetical protein 0.0198 0.0804 0.0949
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0471 0.0536
Brugia malayi CXXC zinc finger family protein 0.0067 0.022 0.024
Brugia malayi hypothetical protein 0.0042 0.0108 0.0107
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0031 0.0031
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1914 0.8469 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0146 0.0572 0.0675
Mycobacterium tuberculosis Conserved hypothetical protein 0.0123 0.0471 0.5
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Echinococcus multilocularis Zinc finger, PHD finger 0.0123 0.0471 0.0471
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1914 0.8469 0.8464
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus granulosus hyperpolarization activated cyclic 0.0146 0.0572 0.0572
Schistosoma mansoni ran 0.0025 0.0031 0.0036
Schistosoma mansoni cpg binding protein 0.0071 0.0237 0.0279
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0123 0.0471 0.0442
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1914 0.8469 1
Echinococcus multilocularis voltage gated potassium channel 0.0146 0.0572 0.0572
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0522
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0471 0.0706
Schistosoma mansoni ryanodine receptor related 0.0146 0.0572 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1537 0.1785
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0123 0.0471 0.0536
Giardia lamblia Phosphatidylinositol 4-kinase 0.0123 0.0471 0.0522
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0123 0.0471 0.0522
Trichomonas vaginalis PIKK family atypical protein kinase 0.1522 0.672 0.7927
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Leishmania major phosphatidylinositol kinase related protein, putative 0.0123 0.0471 0.0442
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.1914 0.8469 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.0572 0.0642
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0146 0.0572 0.0572
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0108 0.0108
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.0362 0.1537 0.1785
Trichomonas vaginalis PIKK family atypical protein kinase 0.1032 0.4529 0.5331
Echinococcus granulosus transient receptor potential cation channel 0.0146 0.0572 0.0572
Echinococcus multilocularis transient receptor potential cation channel 0.0146 0.0572 0.0572
Leishmania major importin beta-1 subunit, putative 0.0027 0.0042 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.1424 0.6278 0.7404
Loa Loa (eye worm) hypothetical protein 0.0123 0.0471 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.1033 0.4536 0.5339
Toxoplasma gondii transporter, cation channel family protein 0.0146 0.0572 0.0867
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0146 0.0572 0.0656
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1914 0.8469 1
Entamoeba histolytica hypothetical protein 0.0027 0.0042 0.0013
Echinococcus multilocularis voltage dependent calcium channel 0.0146 0.0572 0.0572
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0471 0.0536
Echinococcus multilocularis snurportin 1 0.036 0.1526 0.1526
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0082 0.0082
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0403 0.1721 0.2706
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0471 0.0536
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0082 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0123 0.0471 0.0522
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.1424 0.6278 0.7404
Mycobacterium leprae conserved hypothetical protein 0.0123 0.0471 0.5
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0947 0.4152 0.4152
Echinococcus granulosus potassium voltage gated channel protein 0.0146 0.0572 0.0572
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0042 0.0013
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0123 0.0471 0.0522
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni cpg binding protein 0.0071 0.0237 0.0279
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0522
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1914 0.8469 0.8469
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0146 0.0572 0.0572
Echinococcus granulosus geminin 0.0198 0.0804 0.0804
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0146 0.0572 0.0642
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0471 0.0471
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0146 0.0572 0.0656
Schistosoma mansoni hypothetical protein 0.0123 0.0471 0.0557
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0123 0.0471 0.0471
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Leishmania major calcium channel protein, putative,ion transporter, putative 0.2257 1 1
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0146 0.0572 0.0675
Echinococcus granulosus voltage gated potassium channel 0.0146 0.0572 0.0572
Brugia malayi cation channel family protein 0.0146 0.0572 0.0656
Echinococcus granulosus two pore calcium channel protein 2 0.0146 0.0572 0.0572
Toxoplasma gondii transporter, cation channel family protein 0.0146 0.0572 0.0867
Echinococcus multilocularis dnaJ subfamily B 0.0956 0.4189 0.4189
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0123 0.0471 0.0522
Echinococcus granulosus dnaJ subfamily B 0.0956 0.4189 0.4189
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0146 0.0572 0.0867
Loa Loa (eye worm) phosphatidylinositol 3 0.0642 0.2787 0.3276
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0042 0.0013
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0146 0.0572 0.0572
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0031 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.1522 0.672 0.7927
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0146 0.0572 0.0656
Loa Loa (eye worm) voltage-gated calcium channel 0.0146 0.0572 0.0655
Echinococcus granulosus TRP transient receptor potential channel 0.0146 0.0572 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0985 0.1131
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0362 0.1537 0.1785
Echinococcus multilocularis transient receptor potential cation channel 0.0146 0.0572 0.0572
Loa Loa (eye worm) hypothetical protein 0.0362 0.1537 0.1797
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1524 0.6727 0.7935
Echinococcus multilocularis two pore calcium channel protein 1 0.0146 0.0572 0.0572
Echinococcus granulosus transient receptor potential cation channel 0.0146 0.0572 0.0572
Schistosoma mansoni voltage-gated cation channel 0.0146 0.0572 0.0675
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0123 0.0471 0.0522
Toxoplasma gondii histone lysine methyltransferase SET1 0.0128 0.0493 0.0741
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1914 0.8469 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0146 0.0572 0.0867
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0146 0.0572 0.0572
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0123 0.0471 0.0557
Echinococcus granulosus two pore calcium channel protein 1 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.1033 0.4536 0.5339
Echinococcus granulosus hypothetical protein 0.0146 0.0572 0.0572
Trypanosoma cruzi target of rapamycin kinase 3 0.1524 0.6727 0.7935
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0123 0.0471 0.0471
Schistosoma mansoni 60S ribosomal protein L21 0.0146 0.0572 0.0675
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus multilocularis geminin 0.0198 0.0804 0.0804
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.007 0.0047
Entamoeba histolytica hypothetical protein 0.0042 0.0108 0.0091
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0123 0.0471 0.0522
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0146 0.0572 0.0656
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0123 0.0471 0.0557
Leishmania major phosphatidylinositol 3-kinase, putative 0.0642 0.2787 0.2765
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0146 0.0572 0.0656
Toxoplasma gondii FATC domain-containing protein 0.0362 0.1537 0.2411
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0146 0.0572 0.0656
Echinococcus granulosus transient receptor potential cation channel 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.1132 0.4977 0.5862
Echinococcus multilocularis two pore calcium channel protein 2 0.0146 0.0572 0.0572
Echinococcus multilocularis shaker cognate 0.0146 0.0572 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0403 0.1721 0.2004
Giardia lamblia Hypothetical protein 0.0123 0.0471 0.0522
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0471 0.0706
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0146 0.0572 0.0572
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1914 0.8469 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0146 0.0572 0.0572
Echinococcus multilocularis voltage gated potassium channel 0.0146 0.0572 0.0572
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0146 0.0572 0.0656
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0146 0.0572 0.0572
Echinococcus multilocularis hyperpolarization activated cyclic 0.0146 0.0572 0.0572
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0146 0.0572 0.0572
Toxoplasma gondii target of rapamycin (TOR), putative 0.1424 0.6278 1
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Brugia malayi RNA, U transporter 1 0.0096 0.0348 0.0391
Echinococcus granulosus importin subunit beta 1 0.0034 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0642 0.2787 0.3266
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0146 0.0572 0.0642
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Entamoeba histolytica hypothetical protein 0.0123 0.0471 0.0522
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0123 0.0471 0.0522
Echinococcus multilocularis sodium channel protein 0.2257 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0471 0.0536
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0471 0.0471
Echinococcus multilocularis calcium activated potassium channel 0.0146 0.0572 0.0572
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0123 0.0471 0.0471
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.007 0.007
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0123 0.0471 0.0471
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0905 0.3963 0.466
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0146 0.0572 0.0572
Brugia malayi Pre-SET motif family protein 0.0036 0.0082 0.0077
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0146 0.0572 0.0656
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0123 0.0471 0.0522
Trichomonas vaginalis PIKK family atypical protein kinase 0.1914 0.8469 1
Brugia malayi cation channel family protein 0.0146 0.0572 0.0656
Echinococcus multilocularis hyperpolarization activated cyclic 0.0146 0.0572 0.0572
Echinococcus granulosus transient receptor potential cation channel 0.0146 0.0572 0.0572
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0062
Brugia malayi hypothetical protein 0.0146 0.0572 0.0656
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0123 0.0471 0.0522
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0471 0.0538
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0146 0.0572 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0123 0.0471 0.0522
Schistosoma mansoni hypothetical protein 0.0198 0.0804 0.0949
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0642 0.2787 0.3266
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0123 0.0471 0.0522
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0123 0.0471 0.0522
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0123 0.0471 0.0471
Echinococcus granulosus serine protein kinase ATM 0.0362 0.1537 0.1537
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0082 0.0083
Toxoplasma gondii transporter, cation channel family protein 0.0146 0.0572 0.0867
Echinococcus granulosus calcium activated potassium channel 0.0146 0.0572 0.0572
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0146 0.0572 0.0656
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0471 0.0536
Plasmodium vivax hypothetical protein 0.0123 0.0471 1
Onchocerca volvulus 0.0067 0.022 0.1272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0082 0.0097
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0146 0.0572 0.0675
Echinococcus multilocularis short transient receptor potential channel 6 0.0146 0.0572 0.0572
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0362 0.1537 0.1815
Trichomonas vaginalis PIKK family atypical protein kinase 0.1424 0.6278 0.7404
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0123 0.0471 1
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0146 0.0572 0.0642
Schistosoma mansoni hypothetical protein 0.028 0.117 0.1381
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0146 0.0572 0.0572
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0123 0.0471 0.0557
Loa Loa (eye worm) hypothetical protein 0.039 0.1662 0.1945
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0146 0.0572 0.0572
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0146 0.0572 0.0572
Plasmodium vivax hypothetical protein, conserved 0.0123 0.0471 1
Leishmania major hypothetical protein, unknown function 0.0123 0.0471 0.0442
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0146 0.0572 0.0675
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0123 0.0471 1
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0146 0.0572 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.1033 0.4536 0.5339
Echinococcus multilocularis conserved hypothetical protein 0.0146 0.0572 0.0572
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.007 0.0047
Echinococcus multilocularis potassium voltage gated channel protein 0.0146 0.0572 0.0572
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0146 0.0572 0.0655
Leishmania major hypothetical protein, conserved 0.0146 0.0572 0.0543
Trichomonas vaginalis PIKK family atypical protein kinase 0.1132 0.4977 0.5862
Echinococcus multilocularis transient receptor potential cation channel 0.0146 0.0572 0.0572
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1524 0.6727 0.6717
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0362 0.1537 0.1537
Echinococcus granulosus short transient receptor potential channel 6 0.0146 0.0572 0.0572
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0642 0.2787 0.3266
Loa Loa (eye worm) phosphatidylinositol kinase 0.0123 0.0471 0.0536
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0123 0.0471 0.0522
Loa Loa (eye worm) ryanodine receptor 0.0146 0.0572 0.0655
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0123 0.0471 0.0522
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1914 0.8469 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0146 0.0572 0.0675
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0146 0.0572 0.0642
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0642 0.2787 0.3266
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Loa Loa (eye worm) CXXC zinc finger family protein 0.0067 0.022 0.0238
Entamoeba histolytica protein kinase rad3, putative 0.0362 0.1537 0.1785
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0146 0.0572 0.4533
Onchocerca volvulus 0.0278 0.1163 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0146 0.0572 0.0572
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0642 0.2787 0.3266
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0362 0.1537 0.1785
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0471 0.0538
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Trichomonas vaginalis PIKK family atypical protein kinase 0.1424 0.6278 0.7404
Trichomonas vaginalis PIKK family atypical protein kinase 0.1424 0.6278 0.7404
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0123 0.0471 0.0522
Loa Loa (eye worm) ion channel NompC 0.0146 0.0572 0.0655
Leishmania major phosphatidylinositol 4-kinase, putative 0.0123 0.0471 0.0442
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0123 0.0471 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0146 0.0572 0.0655
Schistosoma mansoni cpg binding protein 0.0067 0.022 0.0259
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0042 0.0013
Echinococcus granulosus voltage gated hydrogen channel 1 0.0146 0.0572 0.0572
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0471 0.0706
Echinococcus multilocularis transient receptor potential cation channel 0.0146 0.0572 0.0572
Schistosoma mansoni ran 0.0025 0.0031 0.0036
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0146 0.0572 0.0572
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0146 0.0572 0.0675
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.0076
Echinococcus multilocularis 0.0123 0.0471 0.0471
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.007 0.0064
Entamoeba histolytica hypothetical protein 0.0042 0.0108 0.0091
Echinococcus multilocularis potassium large conductance calcium activated 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.1522 0.672 0.7927
Trichomonas vaginalis PIKK family atypical protein kinase 0.1424 0.6278 0.7404
Loa Loa (eye worm) calcium channel 0.0146 0.0572 0.0655
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0146 0.0572 0.0675
Echinococcus multilocularis transient receptor potential cation channel 0.0146 0.0572 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.1424 0.6278 0.7404
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0123 0.0471 0.0522
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0123 0.0471 0.0557
Schistosoma mansoni voltage-dependent calcium channel 0.0146 0.0572 0.0675
Loa Loa (eye worm) phosphatidylinositol 3 0.1914 0.8469 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0123 0.0471 0.0522
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0642 0.2787 0.2765
Echinococcus granulosus ryanodine receptor 44f 0.0146 0.0572 0.0572
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0572 0.0675
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.028 0.117 0.117
Loa Loa (eye worm) voltage-dependent calcium channel 0.0146 0.0572 0.0655
Brugia malayi Importin beta-1 subunit 0.0034 0.007 0.0063
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0123 0.0471 0.0522
Schistosoma mansoni transient receptor potential channel 4 0.0146 0.0572 0.0675
Brugia malayi Pre-SET motif family protein 0.0245 0.1012 0.1178
Loa Loa (eye worm) hypothetical protein 0.0146 0.0572 0.0655
Brugia malayi olfactory channel protein osm-9 0.0146 0.0572 0.0656

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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