Detailed information for compound 589747

Basic information

Technical information
  • TDR Targets ID: 589747
  • Name: (2R,3S,4R)-2-(hydroxymethyl)-5-[6-(indan-2-yl amino)purin-9-yl]tetrahydrofuran-3,4-diol
  • MW: 383.401 | Formula: C19H21N5O4
  • H donors: 4 H acceptors: 6 LogP: 0.82 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1OC([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1Cc2c(C1)cccc2
  • InChi: 1S/C19H21N5O4/c25-7-13-15(26)16(27)19(28-13)24-9-22-14-17(20-8-21-18(14)24)23-12-5-10-3-1-2-4-11(10)6-12/h1-4,8-9,12-13,15-16,19,25-27H,5-7H2,(H,20,21,23)/t13-,15-,16-,19?/m1/s1
  • InChiKey: NKTIWTYWGRTWOE-XAUNWSGPSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2R,3S,4R)-2-(hydroxymethyl)-5-[6-(2-indanylamino)-9-purinyl]tetrahydrofuran-3,4-diol
  • (3R,4S,5R)-2-[6-(2,3-dihydro-1H-inden-2-ylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
  • (3R,4S,5R)-2-[6-(indan-2-ylamino)purin-9-yl]-5-methylol-tetrahydrofuran-3,4-diol
  • N-(2,3-dihydro-1H-inden-1-yl)adenosine
  • 96323-20-5
  • Adenosine, N-(2,3-dihydro-1H-inden-2-yl)-
  • CI 947
  • PD 117519
  • PD-117519

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0035 0.026 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Echinococcus multilocularis hypothetical protein 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Echinococcus multilocularis integrin alpha ps 0.0067 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0117 0.144 0.144
Brugia malayi hypothetical protein 0.0035 0.026 0.026
Trypanosoma cruzi endonuclease G, putative 0.0079 0.09 1
Schistosoma mansoni integrin beta subunit 0.0179 0.2345 0.2345
Echinococcus multilocularis integrin alpha ps 0.0067 0.0717 0.0717
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0035 0.026 0.026
Brugia malayi Kelch motif family protein 0.0046 0.0422 0.0422
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0079 0.09 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0057 0.0578 0.1466
Brugia malayi hypothetical protein 0.0046 0.0422 0.0422
Onchocerca volvulus 0.0035 0.026 0.054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0035 0.026 0.026
Giardia lamblia Protein tyrosine phosphatase 0.0035 0.026 0.0869
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Schistosoma mansoni endonuclease related 0.0079 0.09 0.09
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0057 0.0578 0.619
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Trypanosoma brucei endonuclease G, putative 0.0079 0.09 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Brugia malayi Protein-tyrosine phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis 0.0035 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0021 0.0054 0.0054
Onchocerca volvulus 0.0035 0.026 0.054
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0185 0.2428 1
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0035 0.026 0.026
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0185 0.2428 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0035 0.026 0.2438
Schistosoma mansoni hypothetical protein 0.0285 0.3875 0.3875
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase 0.0035 0.026 0.026
Schistosoma mansoni atypical protein kinase C 0.0121 0.1496 0.1496
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Echinococcus granulosus Endonuclease G 0.0079 0.09 0.09
Echinococcus granulosus protein kinase c iota type 0.0114 0.1393 0.1393
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0021 0.0054 0.0054
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0079 0.09 0.5
Loa Loa (eye worm) hypothetical protein 0.0046 0.0422 0.0422
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0035 0.026 0.026
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0111 0.1362 0.1362
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Brugia malayi AEL166Cp 0.0021 0.0054 0.0054
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0035 0.026 0.026
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0185 0.2428 1
Brugia malayi hypothetical protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0113 0.1379 0.1379
Schistosoma mansoni hypothetical protein 0.0021 0.0054 0.0054
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0132 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0082 0.0939 0.0939
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0185 0.2428 1
Onchocerca volvulus 0.0035 0.026 0.054
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0132 0.1663 0.1663
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0021 0.0054 0.0054
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Brugia malayi Integrin beta pat-3 precursor 0.0305 0.4154 0.4154
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Onchocerca volvulus 0.0035 0.026 0.054
Echinococcus granulosus ectonucleotide 0.0111 0.1362 0.1362
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0111 0.1362 0.1362
Echinococcus multilocularis protein kinase c iota type 0.0114 0.1393 0.1393
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0035 0.026 0.026
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0035 0.026 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0021 0.0054 0.0054
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0035 0.026 0.026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0035 0.026 0.026
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0132 0.1663 0.1663
Loa Loa (eye worm) integrin beta-2 0.0305 0.4154 0.4154
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0132 0.1663 0.1663
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0578 0.4962
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0709 1 1
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0185 0.2428 1
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0132 0.1663 0.1663
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0285 0.3875 0.3875
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0709 1 1
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0709 1 1
Echinococcus multilocularis integrin alpha ps 0.0032 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0111 0.1362 0.1362
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Echinococcus multilocularis gpi ethanolamine phosphate transferase 3 0.0021 0.0054 0.0054
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0021 0.0054 0.0054
Onchocerca volvulus 0.0035 0.026 0.054
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0035 0.026 0.0869
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0035 0.026 0.026
Brugia malayi Thrombospondin type 1 domain containing protein 0.0285 0.3875 0.3875
Loa Loa (eye worm) protein tyrosine phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0035 0.026 0.026
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0185 0.2428 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0035 0.026 0.0869
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0035 0.026 0.026
Schistosoma mansoni pcd6 interacting protein-related 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Echinococcus granulosus integrin alpha ps 0.0032 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0021 0.0054 0.0054
Brugia malayi hypothetical protein 0.0021 0.0054 0.0054
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Echinococcus granulosus gpi ethanolamine phosphate transferase 3 0.0021 0.0054 0.0054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Leishmania major hypothetical protein, conserved 0.0057 0.0578 0.619
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0079 0.09 1
Echinococcus granulosus protein tyrosine phosphatase n9 0.0035 0.026 0.026
Schistosoma mansoni integrin alpha 0.0149 0.1902 0.1902
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0035 0.026 0.026
Loa Loa (eye worm) integrin alpha pat-2 0.0229 0.3065 0.3065
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0035 0.026 0.0869
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Onchocerca volvulus 0.0035 0.026 0.054
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0132 0.1663 0.1663
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0035 0.026 0.026
Echinococcus multilocularis gpi ethanolamine phosphate transferase 1 0.0021 0.0054 0.0054
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.0255 0.0255
Plasmodium falciparum GPI ethanolamine phosphate transferase 3, putative 0.0021 0.0054 0.5
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0035 0.026 0.026
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Echinococcus granulosus integrin beta 2 0.0226 0.3014 0.3014
Brugia malayi hypothetical protein 0.0035 0.026 0.026
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0035 0.026 0.026
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0185 0.2428 1
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0185 0.2428 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Schistosoma mansoni protein tyrosine phosphatase 0.0035 0.026 0.026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0035 0.026 0.026
Echinococcus multilocularis integrin beta 2 0.0226 0.3014 0.3014
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0111 0.1354 0.1354
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase 1 0.0035 0.026 0.026
Echinococcus multilocularis integrin alpha 3 0.0114 0.14 0.14
Mycobacterium leprae hypothetical protein 0.0021 0.0054 0.5
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0035 0.026 0.026
Schistosoma mansoni protein tyrosine phosphatase 0.0035 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0032 0.0215 0.0215
Onchocerca volvulus 0.0035 0.026 0.054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis Endonuclease G 0.0079 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Echinococcus granulosus integrin alpha 3 0.0114 0.14 0.14
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0035 0.026 0.026
Brugia malayi endonuclease G, mitochondrial precursor 0.0079 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0132 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0035 0.026 0.026
Brugia malayi Integrin alpha pat-2 precursor 0.0149 0.1902 0.1902
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0035 0.026 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Brugia malayi hypothetical protein 0.0021 0.0054 0.0054
Onchocerca volvulus 0.0035 0.026 0.054
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Brugia malayi hypothetical protein 0.0035 0.026 0.026
Schistosoma mansoni integrin alpha-ps 0.0067 0.0717 0.0717
Onchocerca volvulus 0.0132 0.1663 0.4211
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Leishmania major endonuclease G, putative 0.0079 0.09 1
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0035 0.026 0.026
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0021 0.0054 0.0054
Trypanosoma cruzi endonuclease G, putative 0.0079 0.09 1
Onchocerca volvulus 0.0132 0.1663 0.4211
Onchocerca volvulus 0.0185 0.2428 0.6213
Schistosoma mansoni integrin alpha-ps 0.0035 0.0255 0.0255
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0709 1 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0032 0.0215 0.0215
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0185 0.2428 1
Onchocerca volvulus 4.1 G protein, putative homolog 0.0035 0.026 0.054
Onchocerca volvulus 0.0035 0.026 0.054
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0021 0.0054 0.0054
Echinococcus multilocularis transferase 0.0021 0.0054 0.0054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Brugia malayi protein kinase C3,putative 0.0104 0.1252 0.1252
Trypanosoma brucei protein tyrosine phosphatase 1 0.0035 0.026 0.2438
Trypanosoma brucei endonuclease G, putative 0.0079 0.09 1
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0079 0.09 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Onchocerca volvulus 0.0035 0.026 0.054
Echinococcus multilocularis Alkaline phosphatase, core domain 0.0021 0.0054 0.0054
Onchocerca volvulus 0.0035 0.026 0.054
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0035 0.026 0.026
Echinococcus granulosus integrin alpha ps 0.0067 0.0717 0.0717
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0132 0.1663 0.1663
Trypanosoma brucei endonuclease G, putative 0.0079 0.09 1
Schistosoma mansoni protein tyrosine phosphatase 0.0035 0.026 0.026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Echinococcus multilocularis ectonucleotide 0.0111 0.1362 0.1362
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0113 0.1379 0.1379
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0057 0.0578 0.1466
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0578 0.4962
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0021 0.0054 0.0054
Leishmania major tyrosine specific protein phosphatase, putative 0.0035 0.026 0.2438
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0035 0.026 0.026
Loa Loa (eye worm) type I phosphodiesterase/nucleotide pyrophosphatase 0.0021 0.0054 0.0054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0054 0.0054
Echinococcus granulosus transferase 0.0021 0.0054 0.0054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0128 0.1603 0.5
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0035 0.026 0.026
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0185 0.2428 0.2428
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0035 0.026 0.026
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0046 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0021 0.0054 0.0054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0035 0.026 0.026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0035 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0054 0.0054
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0185 0.2428 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.1663 0.1663
Onchocerca volvulus 0.0035 0.026 0.054
Onchocerca volvulus 0.0035 0.026 0.054
Brugia malayi hypothetical protein 0.0035 0.026 0.026
Onchocerca volvulus 0.0285 0.3875 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0035 0.026 0.026
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0185 0.2428 0.2428

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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