Detailed information for compound 63454

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 743.922 | Formula: C38H65NO13
  • H donors: 6 H acceptors: 8 LogP: 1.24 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 3
  • SMILES: OCC[C@H]1C[C@@H](C)C(=O)/C=C/C(=C/[C@@H]([C@H](OC(=O)C[C@H]([C@@H]([C@H]1O[C@@H]1O[C@H](C)[C@H]([C@@H]([C@H]1O)N(C)C)O[C@@H]1O[C@@H](C)[C@@H]([C@](C1)(C)O)O)C)O)CC)CO)/C
  • InChi: 1S/C38H65NO13/c1-10-29-26(19-41)15-20(2)11-12-27(42)21(3)16-25(13-14-40)34(22(4)28(43)17-30(44)50-29)52-37-33(45)32(39(8)9)35(23(5)49-37)51-31-18-38(7,47)36(46)24(6)48-31/h11-12,15,21-26,28-29,31-37,40-41,43,45-47H,10,13-14,16-19H2,1-9H3/b12-11+,20-15+/t21-,22+,23-,24+,25+,26-,28-,29-,31+,32-,33-,34-,35-,36+,37+,38-/m1/s1
  • InChiKey: HAOLCARBNYLYAL-LXKXJHEOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cyclin B, putative 0.0053 0.0089 0.2523
Brugia malayi Protein kinase domain containing protein 0.015 0.0339 0.0379
Echinococcus granulosus adenylate cyclase 9 0.0057 0.0102 0.0098
Loa Loa (eye worm) hypothetical protein 0.0166 0.038 0.0423
Onchocerca volvulus 0.0215 0.0503 0.5839
Onchocerca volvulus 0.0215 0.0503 0.5839
Trypanosoma brucei RNA helicase, putative 0.0101 0.0213 1
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0098 0.0206 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.004 0.0056 0.0202
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.002 0.0005 0.0012
Onchocerca volvulus 0.0114 0.0245 0.2836
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.015 0.0339 0.0335
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0121 0.0263 0.0259
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.0503 0.05
Schistosoma mansoni hypothetical protein 0.0043 0.0064 0.0627
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0092 0.0913
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0092 0.0913
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0064 0.1784
Schistosoma mansoni RAR-like nuclear receptor 0.0114 0.0245 0.2506
Echinococcus granulosus Nuclear hormone receptor HR96 0.0054 0.0092 0.0088
Echinococcus granulosus SWI:SNF matrix associated 0.0121 0.0263 0.0259
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0026 0.0027
Echinococcus granulosus thyroid hormone receptor alpha 0.0054 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Echinococcus granulosus g-protein coupled receptor 0.0215 0.0503 0.05
Brugia malayi hypothetical protein 0.3514 0.8935 1
Echinococcus granulosus ring and YY1 binding protein 0.0043 0.0064 0.006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0114 0.0245 0.0275
Schistosoma mansoni hypothetical protein 0.0028 0.0027 0.024
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0054 0.0092 0.0088
Schistosoma mansoni cpg binding protein 0.0028 0.0026 0.0229
Leishmania major hypothetical protein, conserved 0.0043 0.0064 0.7073
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0121 0.0263 0.0971
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0114 0.0245 0.0275
Onchocerca volvulus Protein ultraspiracle homolog 0.0114 0.0245 0.2836
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.015 0.0339 0.0377
Schistosoma mansoni nuclear hormone receptor 0.0114 0.0245 0.2506
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0215 0.0503 0.05
Brugia malayi steroid hormone receptor 0.0114 0.0245 0.0275
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.004 0.0056 0.0052
Schistosoma mansoni biogenic amine receptor 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0062 0.0113 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0114 0.0245 0.0272
Schistosoma mansoni retinoic acid receptor RXR 0.0114 0.0245 0.2506
Echinococcus multilocularis cyclins 0.0031 0.0034 0.003
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0286 0.0684 0.0681
Trypanosoma brucei aurora B kinase 0.0051 0.0086 0.3914
Echinococcus granulosus peptide allatostatin:somatostatin 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Trichomonas vaginalis cyclins, putative 0.0053 0.0089 0.2523
Entamoeba histolytica cyclin family protein 0.0031 0.0034 0.0888
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Schistosoma mansoni thyroid hormone receptor 0.0114 0.0245 0.2506
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0005 0.0169
Schistosoma mansoni cyclins 0.0031 0.0034 0.0312
Giardia lamblia Kinase, CMGC CDK 0.004 0.0056 0.3788
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0051 0.0084 0.2381
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0027 0.024
Echinococcus granulosus Zinc finger RanBP2 type 0.0043 0.0064 0.006
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0092 0.0088
Loa Loa (eye worm) apoptosis regulator protein 0.0166 0.038 0.0423
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0027 0.0093
Echinococcus multilocularis glutathione S transferase 0.002 0.0006 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0215 0.0503 0.518
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0114 0.0245 0.0242
Echinococcus granulosus dnaJ subfamily B 0.0396 0.0968 0.0964
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0215 0.0503 0.0561
Brugia malayi Bromodomain containing protein 0.0028 0.0027 0.003
Loa Loa (eye worm) TYRA-2 protein 0.0215 0.0503 0.0561
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Brugia malayi PHD-finger family protein 0.0028 0.0027 0.003
Echinococcus granulosus G protein coupled receptor kinase 1 0.0075 0.0146 0.0142
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0054 0.0092 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0167 0.1693
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0114 0.0245 0.0272
Trichomonas vaginalis cyclins, putative 0.0053 0.0089 0.2523
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0215 0.0503 0.0563
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0027 0.0028
Brugia malayi cell division control protein 2 homolog 0.004 0.0056 0.0063
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0121 0.0263 0.7662
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.007
Entamoeba histolytica hypothetical protein 0.0121 0.0263 0.7662
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0054 0.0092 0.0088
Brugia malayi G protein-coupled receptor 0.0215 0.0503 0.0563
Brugia malayi nuclear receptor RXR 0.006 0.0108 0.0121
Brugia malayi G-protein coupled receptor 0.0215 0.0503 0.0563
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0073 0.0142 1
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.002 0.0005 0.0012
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0053 0.0089 0.0098
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0215 0.0503 0.0561
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0051 0.0086 0.3126
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Onchocerca volvulus 0.0055 0.0095 0.1089
Echinococcus granulosus prostaglandin H2 D isomerase 0.0026 0.0021 0.0017
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0134 0.0296 0.0332
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0043 0.0064 0.2889
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.002 0.0005 0.0004
Echinococcus granulosus GPCR family 2 0.0062 0.0113 0.0109
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.002 0.0005 0.0069
Brugia malayi Tachykinin-like peptides receptor 99D 0.0215 0.0503 0.0563
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0215 0.0503 0.518
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0286 0.0684 0.7059
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.004 0.0056 0.0061
Schistosoma mansoni hypothetical protein 0.0062 0.0113 0.1129
Echinococcus multilocularis neuropeptide FF receptor 2 0.0215 0.0503 0.05
Toxoplasma gondii hypothetical protein 0.0024 0.0015 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0362 0.0879 0.0876
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0215 0.0503 0.05
Onchocerca volvulus 0.0215 0.0503 0.5839
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0195 0.0454 0.0506
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus multilocularis cyclin dependent kinase 1 0.004 0.0056 0.0052
Schistosoma mansoni adenoreceptor 0.0215 0.0503 0.518
Echinococcus multilocularis serotonin receptor 0.0215 0.0503 0.05
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0354 0.086 0.8885
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0121 0.0263 0.0259
Loa Loa (eye worm) hypothetical protein 0.006 0.0108 0.0119
Echinococcus multilocularis G-protein coupled receptor, putative 0.0215 0.0503 0.05
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0215 0.0503 0.518
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0098 0.0206 0.0202
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0055 0.0051
Plasmodium falciparum cyclin 0.0031 0.0034 0.1162
Chlamydia trachomatis DNA topoisomerase I 0.0121 0.0263 0.5
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.2084 0.5279 0.5277
Loa Loa (eye worm) hypothetical protein 0.0053 0.0091 0.01
Toxoplasma gondii aurora kinase 0.0051 0.0086 0.0312
Brugia malayi nuclear hormone receptor 0.0114 0.0245 0.0275
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0114 0.0245 0.0242
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Brugia malayi Nuclear hormone receptor E75 0.0054 0.0092 0.0103
Echinococcus multilocularis ecdysone induced protein 78C 0.0114 0.0245 0.0242
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0106 0.1056
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0043 0.0064 0.0072
Echinococcus multilocularis cpg binding protein 0.0029 0.003 0.0026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0046 0.0439
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0064 0.2889
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0043 0.0064 0.0072
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Echinococcus multilocularis fmrfamide receptor 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.015 0.0339 0.0377
Brugia malayi Melatonin receptor type 1A 0.0215 0.0503 0.0563
Onchocerca volvulus 0.002 0.0006 0.0042
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0114 0.0245 0.0242
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0043 0.0064 0.0072
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.006 0.0108 0.1083
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0075 0.0146 0.0142
Schistosoma mansoni neuropeptide receptor 0.0215 0.0503 0.518
Schistosoma mansoni neuropeptide F-like receptor 0.0215 0.0503 0.518
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.002 0.0005 0.0043
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0046 0.0049
Echinococcus granulosus orexin receptor type 2 0.0215 0.0503 0.05
Giardia lamblia Cyclin A 0.0031 0.0034 0.2179
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0215 0.0503 0.05
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0114 0.0245 0.0242
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Echinococcus granulosus cyclin dependent kinase 5 0.004 0.0056 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Onchocerca volvulus 0.0215 0.0503 0.5839
Echinococcus multilocularis adenylate cyclase 9 0.0057 0.0102 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0034 0.0888
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) phosphatidylinositol 3 0.0255 0.0605 0.0675
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0114 0.0245 0.2506
Echinococcus multilocularis cyclins 0.0031 0.0034 0.003
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0215 0.0503 0.5839
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.002 0.0005 0.0043
Echinococcus granulosus g protein coupled receptor 0.0215 0.0503 0.05
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0215 0.0503 0.0563
Brugia malayi Serotonin receptor 0.0215 0.0503 0.0563
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.002 0.0005 0.0043
Echinococcus granulosus somatostatin receptor 0.0215 0.0503 0.05
Brugia malayi Cyclin, N-terminal domain containing protein 0.0031 0.0034 0.0038
Schistosoma mansoni RNA binding protein 0.0043 0.0064 0.0627
Trypanosoma cruzi aurora B kinase, putative 0.0051 0.0086 0.2417
Trichomonas vaginalis cyclin B, putative 0.0053 0.0089 0.2523
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Echinococcus multilocularis cyclins 0.0031 0.0034 0.003
Schistosoma mansoni biogenic amine receptor 0.0215 0.0503 0.518
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.015 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.007
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Onchocerca volvulus 0.0354 0.086 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0083 0.0167 0.0163
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0026 0.0021 0.0175
Brugia malayi ORL1-like opioid receptor 0.0215 0.0503 0.0563
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0215 0.0503 0.0563
Echinococcus granulosus neuropeptides capa receptor 0.0215 0.0503 0.05
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0051 0.0086 0.2417
Schistosoma mansoni brg-1 associated factor 0.0121 0.0263 0.2685
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0104 0.0114
Schistosoma mansoni retinoid-x-receptor (RXR) 0.006 0.0108 0.1083
Echinococcus multilocularis GPCR, family 2 0.0062 0.0113 0.0109
Schistosoma mansoni histamine h1 receptor 0.0215 0.0503 0.518
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.004 0.0056 0.612
Onchocerca volvulus 0.0215 0.0503 0.5839
Echinococcus granulosus aurora kinase A 0.0051 0.0086 0.0082
Loa Loa (eye worm) AUR protein kinase 0.0051 0.0086 0.0094
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0114 0.0245 0.0242
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Echinococcus multilocularis glutathione S transferase 0.0026 0.0021 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0215 0.0503 0.05
Schistosoma mansoni hypothetical protein 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0043 0.0064 0.006
Brugia malayi nuclear receptor NHR-67 0.0054 0.0092 0.0103
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0092 0.0088
Schistosoma mansoni cpg binding protein 0.0029 0.003 0.0271
Onchocerca volvulus 0.0043 0.0064 0.0726
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0215 0.0503 0.05
Onchocerca volvulus 0.0028 0.0026 0.0279
Brugia malayi G protein-coupled receptor F59B2.13 0.0215 0.0503 0.0563
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0043 0.0064 0.0726
Schistosoma mansoni nuclear receptor 0.0054 0.0092 0.0913
Toxoplasma gondii PAN domain-containing protein 0.0287 0.0688 0.2555
Schistosoma mansoni protein kinase 0.0051 0.0086 0.085
Brugia malayi AKH receptor 0.0215 0.0503 0.0563
Onchocerca volvulus 0.0054 0.0092 0.1047
Loa Loa (eye worm) hypothetical protein 0.0495 0.122 0.1364
Echinococcus granulosus cyclin B 0.0053 0.0089 0.0086
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0215 0.0503 0.05
Giardia lamblia G2/mitotic-specific cyclin B 0.0053 0.0089 0.6189
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0114 0.0245 0.0275
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.0296 0.0331
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Schistosoma mansoni amine GPCR 0.0215 0.0503 0.518
Schistosoma mansoni hypothetical protein 0.0166 0.038 0.3901
Plasmodium vivax glutathione S-transferase, putative 0.0026 0.0021 0.0598
Brugia malayi hypothetical protein 0.0054 0.0092 0.0103
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0362 0.0879 0.0876
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.0503 0.05
Echinococcus granulosus neuropeptide FF receptor 2 0.0215 0.0503 0.05
Schistosoma mansoni thyroid hormone receptor 0.0114 0.0245 0.2506
Echinococcus multilocularis neuropeptide receptor A26 0.0215 0.0503 0.05
Brugia malayi nuclear hormone receptor 0.0054 0.0092 0.0103
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.002 0.0005 0.0043
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0215 0.0503 0.05
Echinococcus granulosus neuropeptide receptor 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0142 0.1439
Echinococcus granulosus sex peptide receptor 0.0215 0.0503 0.05
Echinococcus multilocularis orexin receptor type 2 0.0215 0.0503 0.05
Brugia malayi Dopamine receptor protein 2 0.0215 0.0503 0.0563
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0215 0.0503 0.0561
Schistosoma mansoni amine GPCR 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0152 0.0343 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0054 0.0092 0.0913
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0067 0.0127 0.3628
Echinococcus granulosus tachykinin peptides receptor 99D 0.0836 0.2092 0.2089
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0114 0.0245 0.2506
Schistosoma mansoni hypothetical protein 0.0396 0.0968 1
Schistosoma mansoni zinc finger protein 0.0043 0.0064 0.0627
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus granulosus biogenic amine 5HT receptor 0.0215 0.0503 0.05
Onchocerca volvulus 0.0215 0.0503 0.5839
Schistosoma mansoni nuclear receptor nhr-48 0.0054 0.0092 0.0913
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.0503 0.05
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0027 0.0093
Echinococcus multilocularis Zinc finger, PHD finger 0.002 0.0005 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0114 0.0245 0.0242
Plasmodium falciparum protein kinase 5 0.004 0.0056 0.2021
Loa Loa (eye worm) cyclin domain-containing protein 0.0031 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.006 0.0108 0.0119
Trichomonas vaginalis cyclin B3, putative 0.0031 0.0034 0.0888
Schistosoma mansoni zinc finger protein 0.0054 0.0092 0.0913
Schistosoma mansoni hypothetical protein 0.0215 0.0503 0.518
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0027 0.0841
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0215 0.0503 0.05
Brugia malayi neuropeptide F receptor 0.0215 0.0503 0.0563
Echinococcus granulosus tm gpcr rhodopsin 0.0215 0.0503 0.05
Echinococcus multilocularis SWI:SNF matrix associated 0.0121 0.0263 0.0259
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0043 0.0064 0.0072
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Brugia malayi phosphoinositide-dependent protein kinase I 0.015 0.0339 0.0379
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Trypanosoma cruzi cdc2-related kinase 1 0.004 0.0056 0.1544
Echinococcus granulosus neuropeptide s receptor 0.0215 0.0503 0.05
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0215 0.0503 0.0561
Onchocerca volvulus 0.0043 0.0064 0.0726
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0057 0.0102 0.1161
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0098 0.0206 0.023
Loa Loa (eye worm) brahma associated protein 0.0121 0.0263 0.0292
Onchocerca volvulus 0.0215 0.0503 0.5839
Echinococcus granulosus neuropeptide Y receptor 0.0215 0.0503 0.05
Trypanosoma cruzi cyclin 6, putative 0.0053 0.0089 0.2523
Trypanosoma cruzi cyclin, putative 0.0053 0.0089 0.2523
Echinococcus multilocularis fmrfamide receptor 0.0215 0.0503 0.05
Echinococcus granulosus adenylate cyclase type IX 0.0081 0.0161 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0114 0.0245 0.0272
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.002 0.0005 0.0043
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0051 0.0084 0.2381
Echinococcus multilocularis serotonin receptor 0.0215 0.0503 0.05
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0051 0.0084 0.2381
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0215 0.0503 0.05
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0043 0.0064 0.1784
Onchocerca volvulus Bile acid receptor homolog 0.0114 0.0245 0.2836
Echinococcus multilocularis zinc finger protein Ran binding 0.0043 0.0064 0.006
Loa Loa (eye worm) RecQ helicase 0.0019 0.0004 0.0002
Brugia malayi Adenylyl cyclase protein 0.0057 0.0102 0.0114
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0056 0.0543
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0215 0.0503 0.518
Schistosoma mansoni neuropeptide f receptor 76f 0.0215 0.0503 0.518
Brugia malayi CXXC zinc finger family protein 0.0028 0.0026 0.0029
Brugia malayi serine/threonine protein kinase 6 0.0051 0.0086 0.0096
Schistosoma mansoni hypothetical protein 0.0101 0.0213 0.2171
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0166 0.038 0.0376
Schistosoma mansoni hypothetical protein 0.0166 0.038 0.3901
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0114 0.0245 0.2506
Echinococcus multilocularis glutathione S-transferase 0.0026 0.0021 0.0017
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.002 0.0005 0.0043
Loa Loa (eye worm) hypothetical protein 0.006 0.0108 0.0119
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Brugia malayi nuclear hormone receptor family member odr-7 0.0054 0.0092 0.0103
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0004 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0114 0.0245 0.0275
Loa Loa (eye worm) nuclear receptor NHR-67 0.0054 0.0092 0.0101
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0121 0.0263 1
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0031 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.006 0.0108 0.0119
Entamoeba histolytica protein kinase, putative 0.0051 0.0086 0.2417
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0114 0.0245 0.2506
Onchocerca volvulus 0.0215 0.0503 0.5839
Echinococcus multilocularis cyclins 0.0031 0.0034 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0054 0.0092 0.0088
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0215 0.0503 0.0563
Loa Loa (eye worm) hypothetical protein 0.0157 0.0356 0.0396
Schistosoma mansoni nuclear receptor 0.0054 0.0092 0.0913
Plasmodium vivax protein kinase Crk2 0.004 0.0056 0.1976
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0051 0.0086 0.2417
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Brugia malayi ecdysone receptor 0.0054 0.0092 0.0103
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0004 0.0004
Onchocerca volvulus 0.0057 0.0102 0.1161
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0215 0.0503 0.05
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0114 0.0245 0.0275
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0215 0.0503 0.518
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0215 0.0503 0.05
Brugia malayi Serotonin receptor 0.0215 0.0503 0.0563
Brugia malayi larval opioid receptor 0.0215 0.0503 0.0563
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0152 0.0343 1
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0215 0.0503 0.518
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0086 0.085
Brugia malayi jmjC domain containing protein 0.0093 0.0191 0.0214
Onchocerca volvulus Neuropeptide F receptor homolog 0.0215 0.0503 0.5839
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0114 0.0245 0.0272
Echinococcus multilocularis glutathione S transferase 0.0026 0.0021 0.0017
Brugia malayi hypothetical protein 0.006 0.0108 0.0121
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0147 0.0331 0.9661
Loa Loa (eye worm) neuropeptide F receptor 0.0215 0.0503 0.0561
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0215 0.0503 0.05
Trypanosoma cruzi cdc2-related kinase 1 0.004 0.0056 0.1544
Echinococcus granulosus nuclear receptor nhr 48 0.0054 0.0092 0.0088
Echinococcus multilocularis neuropeptide receptor 0.0215 0.0503 0.05
Trypanosoma brucei mitotic cyclin 6 0.0053 0.0089 0.4084
Echinococcus granulosus tm gpcr rhodopsin 0.0215 0.0503 0.05
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.0503 0.05
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0046 0.0073 0.2042
Onchocerca volvulus Alhambra homolog 0.0028 0.0027 0.0291
Schistosoma mansoni hypothetical protein 0.0215 0.0503 0.518
Onchocerca volvulus 0.0215 0.0503 0.5839
Schistosoma mansoni hypothetical protein 0.0166 0.038 0.3901
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0056 0.0543
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0215 0.0503 0.05
Echinococcus granulosus cyclins 0.0031 0.0034 0.003
Giardia lamblia Hypothetical protein 0.0031 0.0034 0.2179
Echinococcus multilocularis somatostatin receptor 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0152 0.0343 1
Echinococcus multilocularis glutathione s transferase mu 0.0026 0.0021 0.0017
Echinococcus granulosus zinc finger protein Ran binding 0.0043 0.0064 0.006
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0166 0.038 0.0425
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0215 0.0503 0.518
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0054 0.0092 0.1047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0215 0.0503 0.518
Echinococcus granulosus cyclins 0.0031 0.0034 0.003
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0043 0.0064 0.1784
Entamoeba histolytica cyclin family protein 0.0031 0.0034 0.0888
Brugia malayi serine/threonine kinase 12 0.0051 0.0086 0.0096
Plasmodium falciparum phosphatidylinositol 3-kinase 0.002 0.0005 0.0056
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.002 0.0005 0.0001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0114 0.0245 0.2506
Echinococcus multilocularis cyclin B3 1 0.0031 0.0034 0.003
Echinococcus granulosus cyclin dependent kinase 0.004 0.0056 0.0052
Onchocerca volvulus 0.0215 0.0503 0.5839
Schistosoma mansoni phosphatidylinositol 4-kinase 0.002 0.0005 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.0108 0.0121
Echinococcus multilocularis dro:myosuppressin receptor 0.0215 0.0503 0.05
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0114 0.0245 0.0242
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.004 0.0056 0.0061
Echinococcus granulosus g protein coupled receptor 0.0215 0.0503 0.05
Echinococcus granulosus peregrin 0.0028 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) hypothetical protein 0.0134 0.0296 0.0329
Echinococcus granulosus cyclins 0.0031 0.0034 0.003
Trichomonas vaginalis cyclin B, putative 0.0031 0.0034 0.0888
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0051 0.0086 0.0082
Brugia malayi nuclear hormone receptor family member nhr-6 0.0054 0.0092 0.0103
Brugia malayi nuclear receptor RXR 0.0054 0.0092 0.0103
Leishmania major hypothetical protein, conserved 0.0043 0.0064 0.7073
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.002 0.0005 0.0015
Schistosoma mansoni hypothetical protein 0.0062 0.0113 0.1129
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0215 0.0503 0.518
Echinococcus multilocularis glutathione S transferase 0.002 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus multilocularis ring and YY1 binding protein 0.0043 0.0064 0.006
Echinococcus granulosus beta-adrenergic receptor kinase 0.0083 0.0167 0.0163
Echinococcus multilocularis SWI:SNF matrix associated 0.0121 0.0263 0.0259
Echinococcus multilocularis thyroid hormone receptor alpha 0.0114 0.0245 0.0242
Brugia malayi serine/threonine-protein kinase 6 0.0051 0.0086 0.0096
Brugia malayi Cyclin, N-terminal domain containing protein 0.0053 0.0089 0.01
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0114 0.0245 0.0275
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0191 0.0187
Toxoplasma gondii ran binding protein 0.0043 0.0064 0.0232
Toxoplasma gondii PAN domain-containing protein 0.0287 0.0688 0.2555
Onchocerca volvulus 0.0121 0.0263 0.3038
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.002 0.0006 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0114 0.0245 0.0275
Onchocerca volvulus 0.0215 0.0503 0.5839
Schistosoma mansoni opsin-like receptor 0.0215 0.0503 0.518
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0495 0.122 0.1366
Schistosoma mansoni hypothetical protein 0.0062 0.0113 0.1129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Echinococcus multilocularis neuropeptide s receptor 0.0215 0.0503 0.05
Trypanosoma cruzi WLM domain containing protein, putative 0.0043 0.0064 0.1784
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0086 0.2417
Echinococcus granulosus cpg binding protein 0.0029 0.003 0.0026
Schistosoma mansoni opsin-like receptor 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0086 0.2417
Trichomonas vaginalis cyclin B, putative 0.0053 0.0089 0.2523
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0114 0.0245 0.0275
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0104 0.0221 0.6415
Brugia malayi photoreceptor-specific nuclear receptor 0.0114 0.0245 0.0275
Schistosoma mansoni hypothetical protein 0.0121 0.0263 0.2685
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0051 0.0086 0.0082
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Entamoeba histolytica cell division protein kinase 2, putative 0.004 0.0056 0.1544
Brugia malayi Dopamine receptor 0.0215 0.0503 0.0563
Echinococcus multilocularis cyclins 0.0031 0.0034 0.003
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0114 0.0245 0.2836
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0114 0.0245 0.0242
Echinococcus multilocularis cyclin B 0.0053 0.0089 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0114 0.0245 0.0275
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0114 0.0245 0.0242
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0054 0.0092 0.0913
Echinococcus multilocularis adenylate cyclase type IX 0.0081 0.0161 0.0157
Brugia malayi RE15519p 0.0215 0.0503 0.0563
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Schistosoma mansoni neuropeptide F-like receptor 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Plasmodium vivax hypothetical protein, conserved 0.0121 0.0263 1
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Brugia malayi Cyclin, N-terminal domain containing protein 0.0053 0.0089 0.01
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus granulosus cyclins 0.0031 0.0034 0.003
Trichomonas vaginalis cyclins, putative 0.0029 0.0029 0.075
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.0108 0.0121
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus granulosus fmrfamide receptor 0.0215 0.0503 0.05
Entamoeba histolytica cyclin, putative 0.0031 0.0034 0.0888
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.006 0.0108 0.0104
Loa Loa (eye worm) hypothetical protein 0.0057 0.0102 0.0112
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0121 0.0263 0.0292
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0215 0.0503 0.518
Loa Loa (eye worm) G-protein coupled receptor 0.0215 0.0503 0.0561
Echinococcus granulosus cyclin dependent kinase 1 0.004 0.0056 0.0052
Brugia malayi brahma associated protein 60 kDa 0.0121 0.0263 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Brugia malayi Cyclin, N-terminal domain containing protein 0.0214 0.05 0.056
Echinococcus granulosus serotonin receptor 0.0215 0.0503 0.05
Brugia malayi nuclear receptor NHR-88 0.0054 0.0092 0.0103
Entamoeba histolytica cyclin, putative 0.0053 0.0089 0.2523
Loa Loa (eye worm) nuclear hormone receptor 0.0054 0.0092 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Brugia malayi glutathione transferase 0.0026 0.0021 0.0023
Echinococcus granulosus glutathione S transferase 0.0026 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0051 0.0084 0.2381
Schistosoma mansoni cyclin B3 0.0031 0.0034 0.0312
Entamoeba histolytica protein kinase , putative 0.0051 0.0086 0.2417
Echinococcus multilocularis peregrin 0.0028 0.0027 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0114 0.0245 0.0272
Loa Loa (eye worm) melatonin receptor type 1A 0.0215 0.0503 0.0561
Trichomonas vaginalis cyclin D, putative 0.0031 0.0034 0.0888
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Echinococcus multilocularis cyclin dependent kinase 1 0.004 0.0056 0.0052
Schistosoma mansoni opsin-like receptor 0.0215 0.0503 0.518
Entamoeba histolytica protein kinase, putative 0.015 0.0339 0.9889
Loa Loa (eye worm) hypothetical protein 0.006 0.0108 0.0119
Loa Loa (eye worm) DR-78 0.0054 0.0092 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0215 0.0503 0.05
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0043 0.0064 0.1784
Schistosoma mansoni neuropeptide receptor 0.0215 0.0503 0.518
Onchocerca volvulus 0.0215 0.0503 0.5839
Schistosoma mansoni apoptosis regulator bax 0.0166 0.038 0.3901
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0053 0.0089 1
Onchocerca volvulus 0.0043 0.0064 0.0726
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0009
Brugia malayi YY1-associated factor 2 0.0043 0.0064 0.0072
Brugia malayi ecdysteroid receptor 0.0114 0.0245 0.0275
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0113 0.0124
Trypanosoma cruzi cdc2-related kinase 3 0.004 0.0056 0.1544
Schistosoma mansoni amine GPCR 0.0215 0.0503 0.518
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0286 0.0684 0.0681
Echinococcus granulosus 7tm_1 domain containing protein 0.0215 0.0503 0.05
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0339 0.3476
Plasmodium falciparum serine/threonine protein kinase, putative 0.0051 0.0086 0.3164
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0114 0.0245 0.2506
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0004 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0056 0.1544
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0004 0.0007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0113 0.0109
Loa Loa (eye worm) hypothetical protein 0.3514 0.8935 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0191 0.0187
Echinococcus granulosus cyclin B3 1 0.0031 0.0034 0.003
Schistosoma mansoni GST class-mu 0.0026 0.0021 0.0175
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.002 0.0005 0.0001
Onchocerca volvulus 0.0053 0.0089 0.1018
Loa Loa (eye worm) hypothetical protein 0.0048 0.0078 0.0086
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0215 0.0503 0.0561
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.002 0.0005 0.0043
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0086 0.2417
Onchocerca volvulus 0.0215 0.0503 0.5839
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0064 0.1784
Onchocerca volvulus 0.0215 0.0503 0.5839
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.004 0.0056 0.612
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0043 0.0064 0.2336
Chlamydia trachomatis SWIB complex protein 0.0121 0.0263 0.5
Trichomonas vaginalis cyclins, putative 0.0053 0.0089 0.2523
Echinococcus multilocularis allatostatin A receptor 0.0354 0.086 0.0857
Echinococcus multilocularis g protein coupled receptor 0.0215 0.0503 0.05
Echinococcus multilocularis neuropeptides capa receptor 0.0215 0.0503 0.05
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0046 0.0439
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0035 0.0045 0.3014
Giardia lamblia PHD finger protein 15 0.0028 0.0027 0.1672
Trichomonas vaginalis cyclin A, putative 0.0053 0.0089 0.2523
Trichomonas vaginalis cyclin D, putative 0.0031 0.0034 0.0888
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0114 0.0245 0.0242
Trypanosoma brucei cdc2-related kinase 3 0.004 0.0056 0.25
Schistosoma mansoni glutathione-S-transferase 0.0026 0.0021 0.0175
Echinococcus multilocularis SWI:SNF matrix associated 0.0121 0.0263 0.0259
Brugia malayi follicle stimulating hormone receptor 0.0215 0.0503 0.0563
Leishmania major protein kinase, putative 0.0051 0.0086 0.9582
Trypanosoma cruzi cyclin, putative 0.0053 0.0089 0.2523
Onchocerca volvulus 0.0054 0.0092 0.1047
Giardia lamblia Aurora kinase 0.0051 0.0086 0.593
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0121 0.0263 1
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.002 0.0005 0.0169
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0215 0.0503 0.0563
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0166 0.038 0.3901
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0051 0.0084 0.3855
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0114 0.0245 0.0275
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Loa Loa (eye worm) AUR protein kinase 0.0051 0.0086 0.0094
Schistosoma mansoni hypothetical protein 0.0134 0.0296 0.303
Echinococcus multilocularis aurora kinase A 0.0051 0.0086 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0086 0.2417
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0114 0.0245 0.0275
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Trypanosoma cruzi cdc2-related kinase 3 0.004 0.0056 0.1544
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0167 0.1693
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0054 0.0092 0.1047
Echinococcus multilocularis glutathione S transferase 0.0026 0.0021 0.0017
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0054 0.0092 0.0101
Loa Loa (eye worm) adenylyl cyclase 3 0.0136 0.0302 0.0336
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0113 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0114 0.0245 0.0275
Plasmodium falciparum glutathione S-transferase 0.0026 0.0021 0.0651
Leishmania major hypothetical protein, conserved 0.0043 0.0064 0.7073
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.006 0.0108 0.0104
Loa Loa (eye worm) AUR protein kinase 0.0051 0.0086 0.0094
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0114 0.0245 0.0242
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Echinococcus multilocularis cyclins 0.0031 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.0054
Loa Loa (eye worm) G-protein coupled receptor 0.0215 0.0503 0.0561
Brugia malayi Nuclear hormone receptor-like 1 0.0114 0.0245 0.0275
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0031 0.0034 0.003
Brugia malayi hypothetical protein 0.006 0.0108 0.0121
Brugia malayi Nuclear hormone receptor E75 0.0054 0.0092 0.0103
Echinococcus granulosus ecdysone induced protein 78C 0.0114 0.0245 0.0242
Brugia malayi putative neuropeptide receptor 0.0215 0.0503 0.0563
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Brugia malayi GnHR receptor homolog 0.0215 0.0503 0.0563
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.002 0.0005 0.0001
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0043 0.0064 0.2889
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0043 0.0064 0.1784
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0114 0.0245 0.0242
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.2084 0.5279 0.5277
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0152 0.0343 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0263 0.764
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0064 0.1784
Onchocerca volvulus 0.0043 0.0064 0.0726
Echinococcus granulosus dro:myosuppressin receptor 0.0215 0.0503 0.05
Echinococcus granulosus FTZ F1 alpha 0.0114 0.0245 0.0242
Schistosoma mansoni neuropeptide receptor 0.0215 0.0503 0.518
Echinococcus granulosus 7TM GPCR rhodopsin 0.0215 0.0503 0.05
Leishmania major hypothetical protein, conserved 0.0043 0.0064 0.7073
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0104 0.0221 0.6415
Trichomonas vaginalis cyclin B, putative 0.0053 0.0089 0.2523
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0027 0.0023
Trypanosoma cruzi WLM domain containing protein, putative 0.0043 0.0064 0.1784
Schistosoma mansoni hypothetical protein 0.0062 0.0113 0.1129
Schistosoma mansoni hypothetical protein 0.0121 0.0263 0.2685
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0051 0.0084 0.0837
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus granulosus glutathione S transferase 0.002 0.0006 0.0002
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.107 0.2688 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0215 0.0503 0.05
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0064 0.2889
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0043 0.0064 0.006
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0121 0.0263 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0215 0.0503 0.518
Trichomonas vaginalis AGC family protein kinase 0.015 0.0339 0.9889
Schistosoma mansoni coup transcription factor 0.0114 0.0245 0.2506
Brugia malayi Dopamine receptor protein 1 0.0215 0.0503 0.0563
Echinococcus granulosus g protein coupled receptor 0.0215 0.0503 0.05
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0056 0.1544
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0002
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0114 0.0245 0.0242
Leishmania major hypothetical protein, conserved 0.0043 0.0064 0.7073
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.0503 0.05
Echinococcus multilocularis cyclins 0.0031 0.0034 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.0503 0.05
Echinococcus multilocularis g protein coupled receptor 0.0215 0.0503 0.05
Echinococcus multilocularis neuropeptide Y receptor 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0121 0.0263 0.0971
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0051 0.0086 0.2417
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0043 0.0064 0.006
Schistosoma mansoni cpg binding protein 0.0029 0.003 0.0271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0114 0.0245 0.0272
Trypanosoma cruzi CYC2-like cyclin, putative 0.0053 0.0089 0.2523
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0027 0.0023
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0836 0.2092 0.2089
Brugia malayi G-protein coupled receptor 0.0215 0.0503 0.0563
Schistosoma mansoni fusion 0.0043 0.0064 0.0627
Brugia malayi brahma associated protein 60 kDa 0.0121 0.0263 0.0294
Trichomonas vaginalis AGC family protein kinase 0.015 0.0339 0.9889
Loa Loa (eye worm) neuropeptide F receptor 0.0215 0.0503 0.0561
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0089 0.0326
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Brugia malayi Protein kinase domain containing protein 0.004 0.0056 0.0063
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Echinococcus granulosus cyclin b3 0.0031 0.0034 0.003
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0215 0.0503 0.518
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0152 0.0343 1
Echinococcus multilocularis neuropeptide Y receptor 0.0215 0.0503 0.05
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0051 0.0084 0.2381
Echinococcus multilocularis g protein coupled receptor 0.0215 0.0503 0.05
Brugia malayi Steroid receptor seven-up type 2 0.0114 0.0245 0.0275
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Echinococcus granulosus glutathione S transferase Mu 1 0.0026 0.0021 0.0017
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0215 0.0503 0.518
Plasmodium falciparum phd finger protein, putative 0.0028 0.0027 0.0892
Brugia malayi orphan nuclear receptor NR2E1 0.0054 0.0092 0.0103
Loa Loa (eye worm) cyclin domain-containing protein 0.0214 0.05 0.0558
Echinococcus multilocularis sex peptide receptor 0.0215 0.0503 0.05
Echinococcus granulosus allatostatin A receptor 0.0354 0.086 0.0857
Schistosoma mansoni cyclin B 0.0053 0.0089 0.0887
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0159 0.0362 0.4193
Loa Loa (eye worm) hypothetical protein 0.006 0.0108 0.0119
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Brugia malayi neuropeptide F receptor 0.0215 0.0503 0.0563
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0026 0.0021 0.0017
Schistosoma mansoni hypothetical protein 0.0215 0.0503 0.518
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0166 0.038 0.0376
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0054 0.0092 0.0103
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0152 0.0343 1
Echinococcus multilocularis neuropeptide receptor 0.0215 0.0503 0.05
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0113 0.0126
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0215 0.0503 0.05
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0114 0.0245 0.0275
Schistosoma mansoni amine GPCR 0.0215 0.0503 0.518
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Schistosoma mansoni neuropeptide receptor 0.0215 0.0503 0.518
Entamoeba histolytica protein kinase, putative 0.0051 0.0086 0.2417
Loa Loa (eye worm) hypothetical protein 0.0354 0.086 0.0961
Echinococcus multilocularis cyclin dependent kinase 0.004 0.0056 0.0052
Schistosoma mansoni TRABID protein (C64 family) 0.0043 0.0064 0.0627
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0073 0.008
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0046 0.0042
Echinococcus multilocularis cyclin dependent kinase 5 0.004 0.0056 0.0052
Echinococcus granulosus Nuclear hormone receptor HR96 0.0054 0.0092 0.0088
Schistosoma mansoni myosin xvIII 0.0215 0.0503 0.518
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Echinococcus multilocularis nuclear receptor nhr 48 0.0054 0.0092 0.0088
Brugia malayi nuclear receptor NHR-88 0.0114 0.0245 0.0275
Brugia malayi PAN domain containing protein 0.0018 0.0002 0.0002
Brugia malayi Glutathione S-transferase 4 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.007
Echinococcus granulosus neuropeptide receptor A26 0.0215 0.0503 0.05
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3931 1 1
Brugia malayi tailless protein 0.0054 0.0092 0.0103
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0152 0.0343 1
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0086 0.2417
Brugia malayi sulfakinin receptor protein 0.3514 0.8935 1
Schistosoma mansoni hypothetical protein 0.0121 0.0263 0.2685
Trichomonas vaginalis cyclins, putative 0.0053 0.0089 0.2523
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.007
Echinococcus granulosus hypothetical protein 0.0215 0.0503 0.05
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0056 0.1544
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0083 0.0167 0.0185
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0215 0.0503 0.05
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0055 0.0051
Entamoeba histolytica cell division protein kinase 2, putative 0.004 0.0056 0.1544
Echinococcus multilocularis FTZ F1 alpha 0.0114 0.0245 0.0242
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0054 0.0092 0.0088
Echinococcus granulosus G protein coupled receptor 139 0.0215 0.0503 0.05
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0215 0.0503 0.518
Brugia malayi SWIB/MDM2 domain containing protein 0.0121 0.0263 0.0294
Echinococcus multilocularis cyclin b3 0.0031 0.0034 0.003
Echinococcus granulosus neuropeptide receptor 0.0215 0.0503 0.05
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0215 0.0503 0.05
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0215 0.0503 0.05
Echinococcus multilocularis g-protein coupled receptor 0.0215 0.0503 0.05
Echinococcus granulosus neuropeptide Y receptor 0.0215 0.0503 0.05
Echinococcus multilocularis G protein coupled receptor 139 0.0215 0.0503 0.05
Giardia lamblia Kinase, CMGC CDK 0.004 0.0056 0.3788
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0051 0.0084 0.2381
Echinococcus granulosus rhodopsin orphan GPCR 0.0215 0.0503 0.05
Brugia malayi hypothetical protein 0.0215 0.0503 0.0563
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0042 0.0038
Loa Loa (eye worm) steroid hormone receptor 0.0114 0.0245 0.0272
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.004 0.0056 0.0061
Loa Loa (eye worm) hypothetical protein 0.0098 0.0206 0.0228
Onchocerca volvulus 0.0215 0.0503 0.5839
Schistosoma mansoni alpha-1 adrenergic receptor 0.0215 0.0503 0.518
Brugia malayi jmjC domain containing protein 0.0036 0.0046 0.0052
Schistosoma mansoni biogenic amine receptor 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.0968 0.0964
Brugia malayi conserved hypotetical protein 0.0054 0.0092 0.0103
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0113 0.0126
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0043 0.0064 0.0232
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0101
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0114 0.0245 0.2506
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0084 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0114 0.0245 0.0272
Echinococcus multilocularis neuropeptides capa receptor 0.0215 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0053 0.0089 0.0098
Onchocerca volvulus 0.0215 0.0503 0.5839
Echinococcus granulosus glutathione s transferase mu 0.0026 0.0021 0.0017
Leishmania major cyclin 0.0053 0.0089 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0195 0.0454 0.0508
Loa Loa (eye worm) hypothetical protein 0.0114 0.0245 0.0272
Brugia malayi hypothetical protein 0.0054 0.0092 0.0103
Brugia malayi putative neuropeptide receptor NPR1 0.0215 0.0503 0.0563
Trichomonas vaginalis AGC family protein kinase 0.015 0.0339 0.9889
Schistosoma mansoni growth hormone secretagogue receptor 0.0215 0.0503 0.518
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.002 0.0005 0.0006
Echinococcus granulosus cyclins 0.0031 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0215 0.0503 0.0561
Echinococcus granulosus neuropeptides capa receptor 0.0215 0.0503 0.05
Trichomonas vaginalis cyclins, putative 0.0031 0.0034 0.0888
Echinococcus granulosus biogenic amine 5HT receptor 0.0215 0.0503 0.05
Trypanosoma brucei cdc2-related kinase 1 0.004 0.0056 0.25
Schistosoma mansoni amine GPCR 0.0215 0.0503 0.518
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0043 0.0064 0.1784
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0215 0.0503 0.518

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 64 ug ml-1 In vitro antimicrobial activity against Staphylococcus pyogenes C203 ChEMBL. 3398001
MIC (functional) = 64 ug ml-1 In vitro antimicrobial activity against Streptococcus pneumoniae ChEMBL. 3398001
MIC (functional) > 128 ug ml-1 In vitro antimicrobial activity against Staphylococcus aureus X1 ChEMBL. 3398001
MIC (functional) = 128 ug ml-1 In vitro antimicrobial activity against Streptococcus epidermidis EPI1 ChEMBL. 3398001
MIC (functional) > 128 ug ml-1 In vitro antimicrobial activity against Streptococcus faecium X66 ChEMBL. 3398001
MIC (functional) > 128 ug ml-1 In vitro antimicrobial activity against Haemophilus influenzae. ChEMBL. 3398001

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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