Detailed information for compound 659623

Basic information

Technical information
  • TDR Targets ID: 659623
  • Name: N-(2,5-dichlorophenyl)-3-fluorobenzamide
  • MW: 284.113 | Formula: C13H8Cl2FNO
  • H donors: 1 H acceptors: 1 LogP: 4.11 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc(c1)C(=O)Nc1cc(Cl)ccc1Cl
  • InChi: 1S/C13H8Cl2FNO/c14-9-4-5-11(15)12(7-9)17-13(18)8-2-1-3-10(16)6-8/h1-7H,(H,17,18)
  • InChiKey: HITRNBPKWQLSEV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,5-dichlorophenyl)-3-fluoro-benzamide
  • NSC214025
  • Oprea1_233328
  • ZINC00064845
  • AN-652/13120051
  • ST004434

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0041 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Treponema pallidum sodium- and chloride- dependent transporter 0.0104 0.0703 0.3089
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0184 0.0375
Brugia malayi vesicular acetylcholine transporter unc-17 0.0692 0.4888 0.4886
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0402 0.8872
Trypanosoma brucei unspecified product 0.0014 0.0061 0.0054
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0402 0.3388
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0184 0.0375
Echinococcus multilocularis serotonin receptor 0.0176 0.1213 0.2042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0184 0.0309
Echinococcus granulosus g protein coupled receptor 0.0031 0.0184 0.0375
Giardia lamblia DINP protein human, muc B family 0.002 0.0105 0.0475
Brugia malayi metabotropic glutamate receptor type 2 0.0015 0.0073 0.0069
Brugia malayi Tyrosine-protein kinase abl-1 0.0065 0.0425 0.0421
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0089 0.0182
Echinococcus granulosus biogenic amine 5HT receptor 0.0176 0.1213 0.2482
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.03 0.0505
Echinococcus multilocularis caspase 0.0155 0.107 0.1801
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0184 0.0369
Loa Loa (eye worm) TK/ABL protein kinase 0.0107 0.0725 0.0725
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0061 0.0054
Loa Loa (eye worm) hypothetical protein 0.0011 0.004 0.004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.03 0.0614
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0089 0.0174
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0184 0.0369
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Schistosoma mansoni vesicular acetylcholine transporter 0.0692 0.4888 1
Schistosoma mansoni hypothetical protein 0.0032 0.0189 0.0381
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0069 0.0452 1
Brugia malayi intermediate filament protein 0.0011 0.004 0.0036
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0045 0.0287 0.0483
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0402 0.0395
Onchocerca volvulus 0.0031 0.0184 0.0297
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0069 0.0452 1
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0184 0.0369
Schistosoma mansoni hypothetical protein 0.0031 0.0184 0.0369
Plasmodium vivax amine transporter, putative 0.0018 0.0089 0.1834
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0184 0.018
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0057 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trypanosoma brucei metacaspase 5, putative 0.0069 0.0452 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0452 0.182
Schistosoma mansoni hypothetical protein 0.0031 0.0184 0.0369
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0105 0.0177
Echinococcus granulosus caspase 3 0.0087 0.0581 0.1189
Brugia malayi putative neuropeptide receptor 0.0031 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0184 0.0369
Schistosoma mansoni biogenic amine (5HT) receptor 0.0176 0.1213 0.2476
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Echinococcus granulosus caspase 2 0.0093 0.0627 0.1282
Plasmodium falciparum transporter, putative 0.0018 0.0089 0.1834
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0184 0.0375
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0184 0.0375
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0189 0.0185
Schistosoma mansoni neuropeptide receptor 0.0228 0.1586 0.324
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0091 0.0084
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0027 0.0152 0.0256
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0105 0.0208
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0155 0.107 0.1801
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0105 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0452 0.182
Brugia malayi Thioredoxin reductase 0.0052 0.0332 0.0328
Echinococcus granulosus GPCR family 2 0.0032 0.0189 0.0388
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0105 0.0098
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0091 0.0084
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Echinococcus multilocularis vesicular acetylcholine transporter 0.0692 0.4888 0.823
Trypanosoma brucei unspecified product 0.0014 0.0061 0.0054
Schistosoma mansoni hypothetical protein 0.0032 0.0189 0.0381
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0184 0.018
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0184 0.0184
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.1834
Trypanosoma cruzi metacaspase 5, putative 0.0069 0.0452 0.0445
Echinococcus granulosus neuropeptide receptor A26 0.0031 0.0184 0.0375
Onchocerca volvulus 0.0045 0.0287 0.051
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.1834
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Echinococcus multilocularis lamin 0.0011 0.004 0.0067
Schistosoma mansoni metabotropic glutamate receptor 0.0015 0.0073 0.0142
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0184 0.0369
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0184 0.0369
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0018 0.0089 0.0149
Loa Loa (eye worm) hypothetical protein 0.0104 0.0703 0.0703
Trypanosoma cruzi C-8 sterol isomerase, putative 0.141 1 1
Schistosoma mansoni biogenic amine receptor 0.0031 0.0184 0.0369
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0402 0.3441
Trichomonas vaginalis cdc25c, putative 0.0045 0.0287 0.0989
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0089 0.0174
Loa Loa (eye worm) norepinephrine transporter 0.0104 0.0703 0.0703
Brugia malayi Rhodanese-like domain containing protein 0.0045 0.0287 0.0283
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0189 0.0319
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Entamoeba histolytica rodhanase-like domain containing protein 0.0045 0.0287 0.0922
Loa Loa (eye worm) glutamate receptor 0.0012 0.0052 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Brugia malayi Dopamine receptor protein 1 0.0031 0.0184 0.018
Onchocerca volvulus 0.0031 0.0184 0.0297
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0089 0.0174
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0189 0.0388
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0184 0.0375
Plasmodium falciparum thioredoxin reductase 0.0018 0.0091 0.1879
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0184 0.0309
Plasmodium vivax metacaspase 1, putative 0.0069 0.0452 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0184 0.0369
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0184 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Echinococcus multilocularis musashi 0.0011 0.004 0.0067
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Schistosoma mansoni adenoreceptor 0.0031 0.0184 0.0369
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0184 0.0369
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0332 0.0558
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0184 0.0309
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0105 0.0098
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0184 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Echinococcus granulosus vesicular acetylcholine transporter 0.0692 0.4888 1
Echinococcus multilocularis serotonin receptor 0.0176 0.1213 0.2042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0184 0.0369
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0091 0.0087
Schistosoma mansoni hypothetical protein 0.0165 0.114 0.2326
Echinococcus multilocularis somatostatin receptor 0.0031 0.0184 0.0309
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0105
Echinococcus multilocularis dna polymerase kappa 0.002 0.0105 0.0177
Loa Loa (eye worm) hypothetical protein 0.0721 0.5093 0.5093
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0184 0.0369
Loa Loa (eye worm) hypothetical protein 0.0042 0.0262 0.0262
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0692 0.4888 1
Schistosoma mansoni neuropeptide receptor 0.0031 0.0184 0.0369
Echinococcus multilocularis GPCR, family 2 0.0032 0.0189 0.0319
Echinococcus granulosus g protein coupled receptor 0.0031 0.0184 0.0375
Schistosoma mansoni amine GPCR 0.0031 0.0184 0.0369
Trypanosoma brucei RNA helicase, putative 0.0223 0.1548 0.1541
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0184 0.0297
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0184 0.0184
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0184 0.018
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0184 0.0375
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.141 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.03 0.03
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0184 0.0309
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0184 0.0184
Trypanosoma cruzi metacaspase, putative 0.0069 0.0452 0.0445
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0184 0.018
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0029 0.0167 0.0163
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0105 0.0843
Onchocerca volvulus 0.0031 0.0184 0.0297
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0091 0.1879
Brugia malayi G-protein coupled receptor 0.0031 0.0184 0.018
Echinococcus granulosus somatostatin receptor 0.0031 0.0184 0.0375
Schistosoma mansoni amine GPCR 0.0031 0.0184 0.0369
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0452 0.0448
Schistosoma mansoni sodium/chloride dependent transporter 0.0104 0.0703 0.1433
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0105 0.0208
Trypanosoma brucei metacaspase MCA3 0.0069 0.0452 0.0445
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0184 0.0309
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0091 0.5
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0184 0.0309
Echinococcus granulosus neuropeptide s receptor 0.0031 0.0184 0.0375
Brugia malayi Receptor family ligand binding region containing protein 0.0008 0.0021 0.0017
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0105 0.0098
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0184 0.0369
Loa Loa (eye worm) hypothetical protein 0.0069 0.0452 0.0452
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0184 0.0375
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Schistosoma mansoni opsin-like receptor 0.0031 0.0184 0.0369
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0089 0.0174
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0045 0.0287 0.0989
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0184 0.0375
Echinococcus granulosus sex peptide receptor 0.0031 0.0184 0.0375
Schistosoma mansoni lamin 0.0011 0.004 0.0074
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0105 0.0161
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.03 0.0296
Entamoeba histolytica rodhanase-like domain containing protein 0.0045 0.0287 0.0922
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0045 0.0287 0.0989
Echinococcus granulosus caspase 8 0.0069 0.0452 0.0924
Loa Loa (eye worm) intermediate filament protein 0.0011 0.004 0.004
Echinococcus multilocularis caspase 3 0.0087 0.0581 0.0978
Loa Loa (eye worm) hypothetical protein 0.0018 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.0994 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Loa Loa (eye worm) hypothetical protein 0.0018 0.0089 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0452 0.182
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0184 0.0309
Schistosoma mansoni biogenic amine receptor 0.0031 0.0184 0.0369
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0105 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Echinococcus multilocularis serotonin transporter 0.0104 0.0703 0.1184
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0018 0.0089 0.0149
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0089 0.0174
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0089 0.0182
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.03 0.0505
Trypanosoma brucei metacaspase 0.0069 0.0452 0.0445
Loa Loa (eye worm) hypothetical protein 0.0104 0.0703 0.0703
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0189 0.0189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0402 0.0676
Brugia malayi TspO/MBR family protein 0.017 0.1171 0.1168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0018 0.0089 0.0089
Trypanosoma brucei unspecified product 0.002 0.0105 0.0098
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0184 0.0309
Plasmodium falciparum metacaspase-like protein 0.0069 0.0452 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0679 0.0675
Brugia malayi ORL1-like opioid receptor 0.0031 0.0184 0.018
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0091 0.0718
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0452 0.182
Schistosoma mansoni lamin 0.0011 0.004 0.0074
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0184 0.0184
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0107 0.0725 0.122
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0184 0.0375
Echinococcus multilocularis caspase 8 0.0069 0.0452 0.0761
Schistosoma mansoni hypothetical protein 0.0223 0.1548 0.3161
Brugia malayi glutathione reductase 0.0052 0.0332 0.0328
Brugia malayi neuropeptide F receptor 0.0031 0.0184 0.018
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Leishmania major trypanothione reductase 0.0052 0.0332 0.0325
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0184 0.0375
Schistosoma mansoni DNA polymerase eta 0.002 0.0105 0.0208
Loa Loa (eye worm) hypothetical protein 0.0176 0.1213 0.1213
Loa Loa (eye worm) hypothetical protein 0.017 0.1171 0.1171
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Schistosoma mansoni biogenic amine receptor 0.0031 0.0184 0.0369
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0091 0.1879
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus neuropeptide receptor 0.0228 0.1586 0.3245
Onchocerca volvulus 0.0018 0.0089 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.03 0.0607
Schistosoma mansoni hypothetical protein 0.0069 0.0452 0.0919
Plasmodium falciparum amino acid transporter, putative 0.0018 0.0089 0.1834
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Brugia malayi neuropeptide F receptor 0.0031 0.0184 0.018
Onchocerca volvulus 0.017 0.1171 0.2334
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0007
Schistosoma mansoni caspase-7 (C14 family) 0.0093 0.0627 0.1276
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Schistosoma mansoni metabotropic glutamate receptor 0.0027 0.0152 0.0304
Brugia malayi Rhodanese-like domain containing protein 0.0045 0.0287 0.0283
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0091 0.1879
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0042 0.0262 0.0262
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0036 0.022 0.0442
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Brugia malayi sulfakinin receptor protein 0.0031 0.0184 0.018
Echinococcus granulosus serotonin transporter 0.0104 0.0703 0.1439
Echinococcus multilocularis apoptotic protease activating factor 1 0.0025 0.0138 0.0233
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0091 0.0718
Onchocerca volvulus 0.0031 0.0184 0.0297
Onchocerca volvulus 0.0031 0.0184 0.0297
Echinococcus multilocularis tyrosine protein kinase Abl 0.0044 0.0273 0.046
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0402 0.0815
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Schistosoma mansoni hypothetical protein 0.0025 0.0138 0.0276
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0402 0.3388
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0184 0.0309
Onchocerca volvulus 0.0045 0.0287 0.051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.03 0.0607
Schistosoma mansoni caspase-7 (C14 family) 0.0155 0.107 0.2183
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0184 0.0309
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0105 0.0101
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0184 0.0369
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0184 0.0375
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0045 0.0287 0.0989
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0155 0.107 0.2189
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0091 0.0718
Loa Loa (eye worm) hypothetical protein 0.0093 0.0627 0.0627
Brugia malayi hypothetical protein 0.0025 0.0138 0.0134
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus multilocularis geminin 0.0165 0.114 0.1919
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0452 0.182
Brugia malayi AKH receptor 0.0031 0.0184 0.018
Onchocerca volvulus 0.0031 0.0184 0.0297
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Toxoplasma gondii hypothetical protein 0.0018 0.0089 0.1834
Plasmodium falciparum metacaspase 1 0.0069 0.0452 1
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0045 0.0287 0.0989
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0105 0.0843
Echinococcus granulosus tyrosine protein kinase ABL1 0.0107 0.0725 0.1482
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0091 0.0084
Plasmodium falciparum glutathione reductase 0.0052 0.0332 0.7295
Plasmodium vivax glutathione reductase, putative 0.0052 0.0332 0.7295
Giardia lamblia Fructose-bisphosphate aldolase 0.0296 0.2074 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0006 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0189 0.0381
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Brugia malayi GnHR receptor homolog 0.0031 0.0184 0.018
Plasmodium vivax hypothetical protein, conserved 0.0069 0.0452 1
Schistosoma mansoni sodium-dependent amino acid transporter 0.0018 0.0089 0.0174
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0105 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0061 0.0054
Onchocerca volvulus 0.0031 0.0184 0.0297
Onchocerca volvulus 0.0031 0.0184 0.0297
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0184 0.0369
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0091 0.5
Loa Loa (eye worm) hypothetical protein 0.01 0.0679 0.0679
Onchocerca volvulus 0.0018 0.0089 0.0101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0069 0.0452 0.0448
Toxoplasma gondii thioredoxin reductase 0.0052 0.0332 0.7295
Mycobacterium ulcerans tryptophan-rich sensory protein 0.017 0.1171 1
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0184 0.0375
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0184 0.018
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0008 0.0021 0.0021
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0184 0.0375
Loa Loa (eye worm) DEAH box polypeptide 35 0.0017 0.0085 0.0085
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Onchocerca volvulus Cell death protein 3 homolog 0.0093 0.0627 0.1211
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0184 0.0375
Trypanosoma brucei C-8 sterol isomerase, putative 0.141 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0184 0.0184
Echinococcus granulosus dna polymerase eta 0.002 0.0105 0.0215
Loa Loa (eye worm) hypothetical protein 0.017 0.1171 0.1171
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0018 0.0089 0.0149
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0025 0.0138 0.0138
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0069 0.0452 0.0918
Echinococcus granulosus hypothetical protein 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.0045 0.0287 0.0287
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0091 0.0153
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0184 0.0184
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0105 0.0098
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0184 0.0184
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0018 0.0089 0.0085
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0402 0.0815
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0089 0.0182
Echinococcus granulosus active breakpoint cluster region 0.0051 0.0328 0.0672
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0089 0.0149
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0184 0.0309
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0184 0.0309
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0184 0.0369
Echinococcus granulosus apoptotic protease activating factor 1 0.0025 0.0138 0.0283
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0184 0.0375
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0091 0.0084
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Schistosoma mansoni opsin-like receptor 0.0031 0.0184 0.0369
Schistosoma mansoni neuropeptide receptor 0.0031 0.0184 0.0369
Plasmodium falciparum thioredoxin reductase 0.0052 0.0332 0.7295
Brugia malayi RE15519p 0.0031 0.0184 0.018
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0089 0.0149
Brugia malayi Serotonin receptor 0.0031 0.0184 0.018
Leishmania major DNA polymerase kappa, putative 0.002 0.0105 0.0098
Onchocerca volvulus 0.0045 0.0287 0.051
Schistosoma mansoni myosin xvIII 0.0031 0.0184 0.0369
Schistosoma mansoni amine GPCR 0.0031 0.0184 0.0369
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0104 0.0703 0.1433
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0332 0.7295
Echinococcus granulosus geminin 0.0165 0.114 0.2332
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus metabotropic glutamate receptor 5 0.0039 0.0241 0.0493
Brugia malayi G-protein coupled receptor 0.0031 0.0184 0.018
Brugia malayi Melatonin receptor type 1A 0.0031 0.0184 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0091 0.0404
Onchocerca volvulus 0.0031 0.0184 0.0297
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0184 0.0309
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0184 0.0375
Trichomonas vaginalis cdc25b, putative 0.0045 0.0287 0.0989
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0105 0.0098
Echinococcus granulosus serotonin receptor 0.0031 0.0184 0.0375
Onchocerca volvulus 0.0031 0.0184 0.0297
Echinococcus granulosus lamin dm0 0.0011 0.004 0.0081
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0184 0.0309
Schistosoma mansoni opsin-like receptor 0.0031 0.0184 0.0369
Plasmodium falciparum glutathione reductase 0.0018 0.0091 0.1879
Schistosoma mansoni histamine h1 receptor 0.0031 0.0184 0.0369
Onchocerca volvulus 0.0018 0.0089 0.0101
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0089 0.0174
Trypanosoma cruzi metacaspase 5, putative 0.0069 0.0452 0.0445
Loa Loa (eye worm) glutamate receptor 0.0032 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0018 0.0089 0.0089
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0089 0.0182
Echinococcus multilocularis caspase 2 0.0093 0.0627 0.1055
Loa Loa (eye worm) hypothetical protein 0.0045 0.0287 0.0287
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0184 0.0309
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0184 0.0184
Schistosoma mansoni amine GPCR 0.0031 0.0184 0.0369
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Toxoplasma gondii hypothetical protein 0.0018 0.0089 0.1834
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0332 0.0332
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0184 0.0297
Trypanosoma cruzi metacaspase, putative 0.0069 0.0452 0.0445
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0089 0.1834
Loa Loa (eye worm) serotonin transporter b 0.0104 0.0703 0.0703
Echinococcus granulosus intermediate filament protein 0.0011 0.004 0.0081
Brugia malayi Dopamine receptor 0.0031 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0089 0.0089
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0091 0.1879
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0184 0.0375
Echinococcus multilocularis dna polymerase eta 0.002 0.0105 0.0177
Schistosoma mansoni neuropeptide receptor 0.0031 0.0184 0.0369
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0189 0.0185
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0189 0.0388
Loa Loa (eye worm) hypothetical protein 0.0176 0.1213 0.1213
Onchocerca volvulus 0.0031 0.0184 0.0297
Loa Loa (eye worm) hypothetical protein 0.0017 0.0085 0.0085
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.0085
Echinococcus multilocularis neuropeptide s receptor 0.0031 0.0184 0.0309
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0105 0.0101
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0018 0.0089 0.0182
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0089 0.0174
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0402 0.0822
Echinococcus multilocularis G protein coupled receptor 139 0.0228 0.1586 0.267
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.0994 0.848
Echinococcus multilocularis neuropeptide receptor A26 0.0031 0.0184 0.0309
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0692 0.4888 0.4888
Echinococcus granulosus metabotropic glutamate receptor 2 0.0027 0.0152 0.0311
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0069 0.0452 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0018 0.0089 0.0182
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Leishmania major DNA polymerase eta, putative 0.002 0.0105 0.0098
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.017 0.1171 0.2391
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0184 0.0184
Echinococcus granulosus fmrfamide receptor 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.017 0.1171 0.1171
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0105 0.0098
Onchocerca volvulus 0.0031 0.0184 0.0297
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0031 0.0184 0.0184
Leishmania major metacaspase, putative 0.0069 0.0452 0.0445
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0091 0.0084
Schistosoma mansoni caspase-3 (C14 family) 0.0155 0.107 0.2183
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0184 0.0309
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0184 0.0309
Echinococcus granulosus caspase 0.0155 0.107 0.2189
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0011 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0032 0.0189 0.0381
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0091 0.0084
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0091 0.0084
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0089 0.0174
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0184 0.0309
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0105 0.0098
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Onchocerca volvulus 0.0031 0.0184 0.0297
Brugia malayi G protein-coupled receptor 0.0031 0.0184 0.018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0184 0.0309
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0679 0.0675
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0089 0.0174
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0184 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0105 0.0215
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0679 0.0679
Brugia malayi polk-prov protein 0.0006 0.0007 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0332 0.2665
Onchocerca volvulus 0.0031 0.0184 0.0297
Echinococcus multilocularis sex peptide receptor 0.0031 0.0184 0.0309
Schistosoma mansoni hypothetical protein 0.0031 0.0184 0.0369
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.2074 1
Onchocerca volvulus 0.017 0.1171 0.2334
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0057 0.0053
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0089 0.0089
Trichomonas vaginalis cdc25b, putative 0.0045 0.0287 0.0989
Echinococcus multilocularis neuropeptide receptor 0.0228 0.1586 0.267
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0184 0.0309
Echinococcus granulosus g protein coupled receptor 0.0031 0.0184 0.0375
Schistosoma mansoni tyrosine kinase 0.0105 0.0714 0.1454
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Leishmania major C-8 sterol isomerase-like protein 0.141 1 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0184 0.0309
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Echinococcus multilocularis translocator protein 0.017 0.1171 0.1972
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0184 0.0375
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0091 0.1879
Onchocerca volvulus 0.017 0.1171 0.2334
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0008 0.0021 0.0021
Brugia malayi Probable ATP-dependent helicase DHX35 0.0017 0.0085 0.0081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0091 0.0186
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0105 0.0073
Onchocerca volvulus 0.0104 0.0703 0.1369
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.03 0.0614
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0184 0.0375
Brugia malayi Dopamine receptor protein 2 0.0031 0.0184 0.018
Echinococcus granulosus orexin receptor type 2 0.0031 0.0184 0.0375
Brugia malayi hypothetical protein 0.0069 0.0451 0.0447
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.2074 1
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0045 0.0287 0.058
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0018 0.0091 1
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0332 0.0325
Loa Loa (eye worm) hypothetical protein 0.0104 0.0703 0.0703
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0184 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0452 0.182
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0184 0.0375
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0045 0.0287 0.0989
Trypanosoma brucei Metacaspase-4 0.0069 0.0452 0.0445
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.0089
Echinococcus multilocularis active breakpoint cluster region 0.0051 0.0328 0.0553
Brugia malayi larval opioid receptor 0.0031 0.0184 0.018
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0091 0.0179
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.0085
Schistosoma mansoni amine GPCR 0.0031 0.0184 0.0369
Loa Loa (eye worm) hypothetical protein 0.0069 0.0452 0.0452
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0184 0.0309
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0184 0.0309
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0184 0.0309
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0098
Loa Loa (eye worm) solute carrier family 6 member 4 0.0104 0.0703 0.0703
Echinococcus granulosus translocator protein 0.017 0.1171 0.2396
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0184 0.0375
Brugia malayi Cell death protein 3 precursor 0.0093 0.0627 0.0623
Loa Loa (eye worm) hypothetical protein 0.0018 0.0089 0.0089
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0184 0.0375
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0184 0.0369
Echinococcus granulosus neuropeptide receptor 0.0031 0.0184 0.0375
Echinococcus granulosus dna polymerase kappa 0.002 0.0105 0.0215
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0105 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0184 0.0369
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0045 0.0287 0.0587
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0184 0.0369
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.03 0.0607
Schistosoma mansoni intermediate filament proteins 0.0011 0.004 0.0074
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0839 0.5939 1
Echinococcus granulosus lamin 0.0011 0.004 0.0081
Onchocerca volvulus 0.0031 0.0184 0.0297
Trypanosoma brucei metacaspase MCA2 0.0069 0.0452 0.0445
Brugia malayi Serotonin receptor 0.0031 0.0184 0.018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.2074 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0039 0.0241 0.0241
Echinococcus multilocularis lamin dm0 0.0011 0.004 0.0067
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0184 0.0369
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.0994 1
Schistosoma mansoni DNA polymerase IV / kappa 0.0006 0.0007 0.0008
Onchocerca volvulus 0.0031 0.0184 0.0297
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0039 0.0241 0.0405
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Brugia malayi Metabotropic glutamate receptor precursor. 0.0032 0.0189 0.0185
Treponema pallidum fructose-bisphosphate aldolase 0.0296 0.2074 1
Entamoeba histolytica rodhanase-like domain containing protein 0.0045 0.0287 0.0922
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0105 0.0105
Onchocerca volvulus 0.0031 0.0184 0.0297
Brugia malayi follicle stimulating hormone receptor 0.0031 0.0184 0.018
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0184 0.0309
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0184 0.0309
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Onchocerca volvulus 0.0045 0.0287 0.051
Onchocerca volvulus 0.017 0.1171 0.2334
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0061 0.0054
Loa Loa (eye worm) hypothetical protein 0.017 0.1171 0.1171
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0402 0.3388
Brugia malayi hypothetical protein 0.0031 0.0184 0.018
Schistosoma mansoni hypothetical protein 0.0031 0.0184 0.0369
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0091 0.1879
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0184 0.0309
Trypanosoma cruzi metacaspase, putative 0.0069 0.0452 0.0445
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0091 0.0084
Onchocerca volvulus 0.0025 0.0138 0.0203
Trypanosoma cruzi metacaspase, putative 0.0069 0.0452 0.0445
Trypanosoma brucei trypanothione reductase 0.0052 0.0332 0.0325
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0184 0.0309
Loa Loa (eye worm) glutathione reductase 0.0052 0.0332 0.0332
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0184 0.0309
Brugia malayi Tyrosine-protein kinase abl-1 0.0044 0.0273 0.027
Brugia malayi Intermediate filament tail domain containing protein 0.0011 0.004 0.0036
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0069 0.0452 0.182
Schistosoma mansoni hypothetical protein 0.0165 0.114 0.2326
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0189 0.0319
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0089 0.1834
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0184 0.0309
Echinococcus granulosus allatostatin A receptor 0.0031 0.0184 0.0375
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0105 0.0098
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0184 0.0309
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0184 0.0369
Brugia malayi hypothetical protein 0.0018 0.0089 0.0085
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0089 0.0174
Loa Loa (eye worm) hypothetical protein 0.0031 0.0184 0.0184
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0104 0.0703 0.07
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0332 0.0678

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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