Detailed information for compound 766627

Basic information

Technical information
  • TDR Targets ID: 766627
  • Name: 1-[4-(4-chlorophenoxy)butyl]-4-methylpiperidi ne
  • MW: 281.821 | Formula: C16H24ClNO
  • H donors: 0 H acceptors: 0 LogP: 4.55 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1CCN(CC1)CCCCOc1ccc(cc1)Cl
  • InChi: 1S/C16H24ClNO/c1-14-8-11-18(12-9-14)10-2-3-13-19-16-6-4-15(17)5-7-16/h4-7,14H,2-3,8-13H2,1H3
  • InChiKey: FCWNKOGXGZOGSO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[4-(4-chlorophenoxy)butyl]-4-methyl-piperidine
  • EU-0083171
  • CBMicro_047038
  • BIM-0046988.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii transporter, major facilitator family protein 0.0064 0.023 0.0327
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0026 0.0029 0.0024
Giardia lamblia Sugar-proton symporter 0.0064 0.023 0.346
Onchocerca volvulus 0.0155 0.0705 0.6082
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0107 0.0468
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0099 0.0114
Schistosoma mansoni hypothetical protein 0.0107 0.0457 0.0583
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.006 0.0041
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0718 0.2836
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0303 0.0373
Echinococcus granulosus glycyl tRNA synthetase 0.0026 0.0029 0.0019
Loa Loa (eye worm) hypothetical protein 0.0139 0.0625 0.1551
Brugia malayi CXXC zinc finger family protein 0.0088 0.0357 0.0853
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0043 0.0014
Onchocerca volvulus 0.0236 0.113 1
Echinococcus granulosus microtubule associated protein 2 0.1429 0.7364 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0137 0.061 0.1513
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0113 0.0495
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus granulosus calcium dependent protein kinase 0.0131 0.0579 0.0767
Brugia malayi Sugar transporter family protein 0.0456 0.2276 0.5858
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0256 0.1124
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.006 0.0041
Plasmodium vivax calcium-dependent protein kinase, putative 0.014 0.0625 0.0597
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0155 0.019
Schistosoma mansoni glucose transport protein 0.0456 0.2276 0.3063
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0159 0.0728 0.4949
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0102 0.0427 0.6932
Trypanosoma brucei glucose transporter 1E 0.0141 0.0634 0.4296
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Toxoplasma gondii protein kinase, putative 0.1287 0.6622 1
Echinococcus granulosus survival motor neuron protein 1 0.076 0.3865 0.5238
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0137 0.061 0.8745
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.023 0.1012
Schistosoma mansoni cpg binding protein 0.0093 0.0383 0.0482
Onchocerca volvulus 0.0064 0.023 0.1698
Plasmodium falciparum calcium-dependent protein kinase 3 0.014 0.0625 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0044 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.023 0.1012
Schistosoma mansoni cpg binding protein 0.0093 0.0383 0.0482
Schistosoma mansoni sugar transporter 0.0064 0.023 0.0274
Giardia lamblia PHD finger protein 15 0.0029 0.0046 0.029
Echinococcus granulosus Sugar transporter ERD6 protein 0.0064 0.023 0.0292
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0044 0.0039
Onchocerca volvulus 0.0064 0.023 0.1698
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0099 0.0182
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.0717 0.1793
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0064 0.023 0.0871
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0046 0.0023
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0026 0.0029 0.0019
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0099 0.0114
Schistosoma mansoni protein kinase 0.0139 0.0625 0.0811
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0107 0.1317
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0099 0.0114
Onchocerca volvulus 0.0064 0.023 0.1698
Schistosoma mansoni hypothetical protein 0.0153 0.0693 0.0905
Echinococcus granulosus solute carrier family 22 0.0064 0.023 0.0292
Echinococcus multilocularis chromobox protein 1 0.0069 0.0256 0.0327
Echinococcus multilocularis calcium dependent protein kinase 0.0131 0.0579 0.0767
Echinococcus multilocularis lysyl tRNA synthetase 0.0102 0.0427 0.056
Echinococcus granulosus synaptic vesicle 2 protein 0.0064 0.023 0.0292
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0303 0.0391
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0115 0.0701
Schistosoma mansoni hypothetical protein 0.005 0.0155 0.0172
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0048 0.0148 0.1902
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0303 0.133
Entamoeba histolytica hypothetical protein 0.0153 0.0693 1
Trichomonas vaginalis myo-inositol transporter, putative 0.0064 0.023 0.1012
Echinococcus granulosus Threonyl tRNA synthetase C 0.0026 0.0029 0.0019
Giardia lamblia Lysyl-tRNA synthetase 0.0102 0.0427 0.6849
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0159 0.0728 0.1081
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0457 0.1115
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0303 0.133
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0099 0.0436
Loa Loa (eye worm) hypothetical protein 0.0107 0.0457 0.1115
Leishmania major mitochondrial DNA polymerase beta 0.0299 0.1457 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0414 0.0543
Schistosoma mansoni protein kinase 0.0139 0.0625 0.0811
Brugia malayi lysyl-tRNA synthetase 0.0102 0.0427 0.1036
Trichomonas vaginalis glucose transporter, putative 0.0064 0.023 0.1012
Mycobacterium tuberculosis Conserved protein 0.0078 0.0303 0.1163
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Brugia malayi Inositol-1 0.004 0.0107 0.0201
Leishmania major protein kinase, putative 0.0139 0.0625 0.4231
Toxoplasma gondii sugar transporter ST2 0.0064 0.023 0.0327
Brugia malayi beta-lactamase family protein 0.0078 0.0303 0.0712
Brugia malayi beta-lactamase 0.0078 0.0303 0.0712
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0107 0.0643
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0303 0.4102
Brugia malayi Major Facilitator Superfamily protein 0.0064 0.023 0.0524
Schistosoma mansoni inositol monophosphatase 0.004 0.0107 0.0105
Plasmodium falciparum calcium-dependent protein kinase 5 0.014 0.0625 0.0597
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0736 0.3743 0.5643
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0303 0.1163
Loa Loa (eye worm) hypothetical protein 0.005 0.0155 0.0329
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Plasmodium vivax CDK-related protein kinase 6, putative 0.1933 1 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0099 0.0592
Entamoeba histolytica hypothetical protein 0.0102 0.0427 0.599
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0456 0.2276 0.3076
Echinococcus granulosus cpg binding protein 0.0093 0.0383 0.05
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0155 0.0705 0.1762
Brugia malayi Major Facilitator Superfamily protein 0.0064 0.023 0.0524
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.023 0.1012
Echinococcus multilocularis solute carrier family 22 0.0064 0.023 0.0292
Echinococcus granulosus neuropeptide s receptor 0.0489 0.2451 0.3314
Chlamydia trachomatis lysine--tRNA ligase 0.0102 0.0427 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.006 0.006
Mycobacterium tuberculosis Conserved protein 0.0078 0.0303 0.1163
Leishmania major hypothetical protein, conserved 0.0028 0.0043 0.0203
Brugia malayi hypothetical protein 0.0064 0.023 0.0524
Loa Loa (eye worm) hypothetical protein 0.0078 0.0303 0.0712
Trichomonas vaginalis esterase, putative 0.0078 0.0303 0.133
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0115 0.0701
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0137 0.061 0.1513
Echinococcus multilocularis solute carrier family 22 0.0064 0.023 0.0292
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0625 0.2744
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0107 0.1163
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0099 0.0114
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0303 0.0712
Leishmania major glucose transporter/membrane transporter D2, putative 0.0141 0.0634 0.4296
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0038 0.0169
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Schistosoma mansoni lysyl-tRNA synthetase 0.0102 0.0427 0.0542
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0155 0.019
Loa Loa (eye worm) major facilitator superfamily transporter 0.0064 0.023 0.0524
Brugia malayi Sugar transporter family protein 0.0064 0.023 0.0524
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.014 0.0625 0.0925
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0026 0.0029 0.0221
Trichomonas vaginalis sugar transporter, putative 0.0141 0.0634 0.2785
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Toxoplasma gondii facilitative glucose transporter GT1 0.0456 0.2276 0.3424
Echinococcus granulosus neuropeptide receptor A26 0.0489 0.2451 0.3314
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Schistosoma mansoni hypothetical protein 0.005 0.0155 0.0172
Leishmania major myo-inositol/proton symporter (MIT) 0.0064 0.023 0.1499
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0043 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Schistosoma mansoni glucose transporter 0.0064 0.023 0.0274
Plasmodium vivax lysine--tRNA ligase, putative 0.0102 0.0427 0.0399
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0091 0.0161
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0086 0.0347 0.1341
Onchocerca volvulus 0.0064 0.023 0.1698
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus granulosus peregrin 0.0029 0.0046 0.0042
Schistosoma mansoni survival motor neuron protein 0.0155 0.0705 0.0921
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0044 0.0038
Trichomonas vaginalis glucose transporter, putative 0.0141 0.0634 0.2785
Trypanosoma brucei sugar transporter, putative 0.0064 0.023 0.1499
Treponema pallidum prolyl-tRNA synthetase 0.0048 0.0148 1
Echinococcus granulosus jumonji domain containing protein 0.004 0.0105 0.0122
Brugia malayi jmjC domain containing protein 0.0094 0.0389 0.0938
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0099 0.0436
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Loa Loa (eye worm) hypothetical protein 0.076 0.3865 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0479 0.2397 0.6172
Onchocerca volvulus 0.0064 0.023 0.1698
Echinococcus multilocularis neuropeptide receptor 0.0159 0.0725 0.0965
Echinococcus granulosus dnaJ subfamily B 0.0424 0.2112 0.2853
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0303 0.133
Plasmodium falciparum hexose transporter 0.0456 0.2276 0.2253
Echinococcus granulosus solute carrier family 22 0.0064 0.023 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0046
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0107 0.0468
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0102 0.0427 0.5865
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0107 0.014
Trypanosoma cruzi hexose transporter, putative 0.0077 0.0299 0.1976
Brugia malayi Pre-SET motif family protein 0.0031 0.006 0.0079
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0736 0.3743 0.3724
Echinococcus multilocularis glycyl tRNA synthetase 0.0026 0.0029 0.0019
Brugia malayi hypothetical protein 0.0064 0.023 0.0524
Loa Loa (eye worm) hypothetical protein 0.0078 0.0303 0.0712
Brugia malayi hypothetical protein 0.0064 0.023 0.0524
Trypanosoma cruzi glucose transporter, putative 0.0064 0.023 0.1499
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Loa Loa (eye worm) hypothetical protein 0.0078 0.0303 0.0712
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0043 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.0634 0.2785
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0159 0.0728 0.4949
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0043 0.0014
Leishmania major hypothetical protein, conserved 0.0064 0.023 0.1499
Toxoplasma gondii sugar transporter ST3 0.0064 0.023 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0625 0.0811
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0498 0.2497 1
Leishmania major glucose transporter, lmgt3 0.0141 0.0634 0.4296
Onchocerca volvulus 0.0078 0.0303 0.2367
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0163 0.1034
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0139 0.0625 0.0828
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0014 0.0061
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0064 0.023 0.3073
Onchocerca volvulus 0.0064 0.023 0.1698
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.0029 0.0108
Plasmodium falciparum mitogen-activated protein kinase 2 0.0736 0.3743 0.3724
Plasmodium vivax proline--tRNA ligase, putative 0.0159 0.0728 0.0701
Trichomonas vaginalis sugar transporter, putative 0.0141 0.0634 0.2785
Entamoeba histolytica protein kinase, putative 0.0139 0.0625 0.8967
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0119 0.0122
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.014 0.0625 0.0597
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0139 0.0625 0.0828
Onchocerca volvulus 0.0043 0.0119 0.067
Onchocerca volvulus Putative transporter 0.0064 0.023 0.1698
Brugia malayi major facilitator superfamily protein 0.0064 0.023 0.0524
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0056 0.0189 0.0415
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0059 0.0259
Trypanosoma cruzi hexose transporter, putative 0.0141 0.0634 0.4296
Entamoeba histolytica protein kinase, putative 0.0139 0.0625 0.8967
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0011 0.0046
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0026 0.0029 0.0129
Leishmania major threonyl-tRNA synthetase, putative 0.0026 0.0029 0.0108
Entamoeba histolytica hypothetical protein 0.0153 0.0693 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0064
Mycobacterium tuberculosis Conserved protein 0.0078 0.0303 0.1163
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0303 0.1163
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0139 0.0625 0.0828
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0139 0.0625 0.1551
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0102 0.0427 0.5865
Echinococcus granulosus GPCR family 2 0.005 0.0155 0.019
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0104 0.012
Loa Loa (eye worm) sugar transporter 0.0064 0.023 0.0524
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0635 0.4301
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0113 0.0614
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0044
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0155 0.019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0059 0.0259
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.0079
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0064 0.023 0.0871
Echinococcus granulosus General substrate transporter 0.0391 0.1942 0.2621
Onchocerca volvulus 0.0064 0.023 0.1698
Brugia malayi Latrophilin receptor protein 2 0.005 0.0155 0.0329
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0303 0.133
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0288 0.0352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0003 0.0013
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0078 0.0085
Onchocerca volvulus 0.0064 0.023 0.1698
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0256 0.1124
Schistosoma mansoni sugar transporter 0.0064 0.023 0.0274
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0414 0.0543
Echinococcus granulosus neuropeptide receptor 0.0159 0.0725 0.0965
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0107 0.0643
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0099 0.1054
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0389 0.0508
Leishmania major glucose transporter, lmgt2 0.0141 0.0634 0.4296
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.0029 0.0108
Echinococcus multilocularis geminin 0.019 0.0888 0.1187
Onchocerca volvulus 0.0064 0.023 0.1698
Trypanosoma cruzi hexose transporter, putative 0.0141 0.0634 0.4296
Toxoplasma gondii lysine-tRNA ligase 0.0102 0.0427 0.0625
Toxoplasma gondii glycyl-tRNA synthetase 0.0026 0.0029 0.0024
Echinococcus multilocularis General substrate transporter 0.0391 0.1942 0.2621
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0139 0.0625 0.1551
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0139 0.0625 0.0828
Brugia malayi chromobox protein homolog 3 0.0039 0.0097 0.0177
Onchocerca volvulus 0.0088 0.0357 0.2866
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0303 0.0274
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0099 0.0592
Plasmodium falciparum calcium-dependent protein kinase 4 0.014 0.0625 0.0597
Mycobacterium ulcerans lipase LipD 0.0078 0.0303 0.4102
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0357 0.0853
Schistosoma mansoni hypothetical protein 0.005 0.0155 0.0172
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0099 0.0114
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0046 0.0049
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0139 0.0625 0.0828
Echinococcus multilocularis neuropeptide receptor A26 0.0489 0.2451 0.3314
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0099 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0097 0.0428
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0303 0.133
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Schistosoma mansoni hypothetical protein 0.0424 0.2112 0.2839
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0153 0.0693 0.0922
Mycobacterium ulcerans sugar transporter 0.0064 0.023 0.3073
Schistosoma mansoni hypothetical protein 0.0029 0.0046 0.0023
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0086 0.0347 0.1341
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Brugia malayi hypothetical protein 0.0028 0.0043 0.0036
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Plasmodium falciparum calcium-dependent protein kinase 1 0.014 0.0625 0.0597
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0064 0.023 0.0274
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0139 0.0625 0.0828
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0046 0.0042
Onchocerca volvulus 0.0064 0.023 0.1698
Schistosoma mansoni glucose transport protein 0.0456 0.2276 0.3063
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0099 0.0592
Brugia malayi Heterochromatin protein 1 0.0069 0.0256 0.059
Schistosoma mansoni hypothetical protein 0.0456 0.2276 0.3063
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.0717 0.1793
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0026 0.0029 0.0262
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0102 0.0427 0.2862
Loa Loa (eye worm) sugar transporter 0.0456 0.2276 0.5858
Plasmodium vivax SET domain protein, putative 0.0031 0.006 0.003
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0139 0.0625 0.0828
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0155 0.0329
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.014 0.0625 0.0597
Giardia lamblia Prolyl-tRNA synthetase 0.0137 0.061 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0099 0.1205
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0303 0.1163
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Brugia malayi follicle stimulating hormone receptor 0.0479 0.2397 0.6172
Brugia malayi Cam kinase protein 1 0.0139 0.0625 0.1551
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.006 0.006
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0043 0.0014
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0084 0.1185
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0026 0.0029 0.0063
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0102 0.0427 0.1875
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0256 0.059
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0102 0.0427 0.2862
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0113 0.0495
Loa Loa (eye worm) hypothetical protein 0.0078 0.0303 0.0712
Brugia malayi PHD-finger family protein 0.0029 0.0046 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0014 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.2276 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0104 0.0102
Echinococcus multilocularis microtubule associated protein 2 0.1429 0.7364 1
Loa Loa (eye worm) beta-lactamase 0.0078 0.0303 0.0712
Brugia malayi jmjC domain containing protein 0.004 0.0104 0.0195
Entamoeba histolytica hypothetical protein 0.0153 0.0693 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0414 0.0543
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0456 0.2276 0.3076
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0139 0.0625 0.1551
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0456 0.2276 0.3076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0059 0.0259
Entamoeba histolytica hypothetical protein 0.0153 0.0693 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0141 0.0634 0.4296
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0207 0.0462
Mycobacterium ulcerans integral membrane transport protein 0.0064 0.023 0.3073
Trypanosoma cruzi sugar transporter, putative 0.0064 0.023 0.1499
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0635 0.4301
Trypanosoma brucei glucose transporter 2A 0.0141 0.0634 0.4296
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0046 0.0044
Toxoplasma gondii hypothetical protein 0.0048 0.0147 0.0202
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.014 0.0625 0.0925
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0115 0.0701
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0414 0.0543
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0044 0.0038
Schistosoma mansoni hypothetical protein 0.005 0.0155 0.0172
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0981 0.2481
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0043 0.0203
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus multilocularis G protein coupled receptor 139 0.0159 0.0725 0.0965
Echinococcus multilocularis solute carrier family 22 0.0064 0.023 0.0292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0414 0.0525
Trypanosoma cruzi hexose transporter, putative 0.0141 0.0634 0.4296
Echinococcus granulosus solute carrier family 22 0.0064 0.023 0.0292
Giardia lamblia Hexose transporter 0.0064 0.023 0.346
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0105 0.0122
Brugia malayi hypothetical protein 0.076 0.3865 1
Plasmodium vivax sugar transporter, putative 0.0064 0.023 0.0201
Schistosoma mansoni chromobox protein 0.0069 0.0256 0.0309
Schistosoma mansoni cpg binding protein 0.0088 0.0357 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0097 0.0428
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0026 0.0029 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0097 0.0177
Trichomonas vaginalis sugar transporter, putative 0.0141 0.0634 0.2785
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0303 0.1163
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0065 0.0049
Loa Loa (eye worm) hypothetical protein 0.0078 0.0303 0.0712
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0089 0.0361 0.1588
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0456 0.2276 0.3076
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0099 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0188 0.0879 0.1159
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0064 0.023 0.0201
Trichomonas vaginalis sugar transport protein, putative 0.0064 0.023 0.1012
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0064 0.023 0.3073
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0137 0.061 0.0808
Toxoplasma gondii histone lysine methyltransferase SET1 0.0168 0.0775 0.1152
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0303 0.0373
Brugia malayi major facilitator superfamily protein 0.0064 0.023 0.0524
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0064 0.023 0.1499
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0153 0.0693 0.0922
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Loa Loa (eye worm) hypothetical protein 0.0028 0.0043 0.0036
Onchocerca volvulus 0.0064 0.023 0.1698
Schistosoma mansoni sugar transporter 0.0064 0.023 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.023 0.1012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0389 0.0508
Loa Loa (eye worm) hypothetical protein 0.0137 0.061 0.1513
Plasmodium falciparum protein kinase 7 0.1287 0.6622 0.6612
Loa Loa (eye worm) hypothetical protein 0.0078 0.0303 0.0712
Plasmodium falciparum phd finger protein, putative 0.0029 0.0046 0.0017
Toxoplasma gondii sugar transporter ST1 0.0064 0.023 0.0327
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0104 0.0195
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.006 0.006
Brugia malayi Sugar transporter family protein 0.0064 0.023 0.0524
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.023 0.1012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0059 0.0259
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.1457 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0919 0.4701 0.6375
Mycobacterium leprae Probable lipase LipE 0.0078 0.0303 0.4847
Onchocerca volvulus 0.0078 0.0303 0.2367
Echinococcus multilocularis GPCR, family 2 0.005 0.0155 0.019
Leishmania major lysyl-tRNA synthetase, putative 0.0102 0.0427 0.2862
Schistosoma mansoni chromobox protein 0.0069 0.0256 0.0309
Trypanosoma cruzi hexose transporter 0.0141 0.0634 0.4296
Trichomonas vaginalis set domain proteins, putative 0.0236 0.113 0.4963
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0137 0.061 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.0064 0.023 0.0292
Onchocerca volvulus 0.0064 0.023 0.1698
Onchocerca volvulus 0.0064 0.023 0.1698
Echinococcus multilocularis solute carrier family 22 0.0064 0.023 0.0292
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Schistosoma mansoni transcription factor LCR-F1 0.0153 0.0693 0.0905
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2276 0.3076
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0159 0.0728 0.4949
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0303 0.2001
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0139 0.0625 0.4231
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0107 0.0124
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2276 0.3076
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0064 0.023 0.0292
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0107 0.0643
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2276 0.3076
Plasmodium falciparum proline--tRNA ligase 0.0159 0.0728 0.0701
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0107 0.0124
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0635 0.4301
Trypanosoma brucei glucose transporter, putative 0.0141 0.0634 0.4296
Trypanosoma brucei THT1 - hexose transporter, putative 0.0141 0.0634 0.4296
Trypanosoma cruzi hexose transporter, putative 0.0064 0.023 0.1499
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0104 0.0102
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0299 0.1457 1
Schistosoma mansoni hypothetical protein 0.019 0.0888 0.117
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.1457 1
Schistosoma mansoni microtubule-associated protein tau 0.1429 0.7364 1
Echinococcus multilocularis survival motor neuron protein 1 0.076 0.3865 0.5238
Echinococcus multilocularis cpg binding protein 0.0093 0.0383 0.05
Onchocerca volvulus 0.0064 0.023 0.1698
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0414 0.0525
Schistosoma mansoni glucose transport protein 0.0456 0.2276 0.3063
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0303 0.0391
Brugia malayi Major Facilitator Superfamily protein 0.0064 0.023 0.0524
Brugia malayi beta-lactamase family protein 0.0078 0.0303 0.0712
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0139 0.0625 0.0828
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0038 0.0169
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0084 0.0284
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0099 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.0634 0.2785
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0159 0.0728 0.4949
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0137 0.061 0.0791
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0115 0.0701
Leishmania major hypothetical protein, conserved 0.0078 0.0303 0.2001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0414 0.0525
Schistosoma mansoni neuropeptide receptor 0.0159 0.0725 0.0948
Plasmodium falciparum calcium-dependent protein kinase 2 0.014 0.0625 0.0597
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0059 0.0259
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0097 0.0473
Loa Loa (eye worm) hypothetical protein 0.0049 0.0154 0.0325
Echinococcus multilocularis peregrin 0.0029 0.0046 0.0042
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0026 0.0029 0.0108
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0303 0.1163
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0137 0.061 0.0791
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0046 0.0049
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0086 0.0347 0.5587
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0059 0.0259
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.0717 0.1793
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0155 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0014 0.0061
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0107 0.3842
Loa Loa (eye worm) hypothetical protein 0.0157 0.0717 0.1793
Onchocerca volvulus 0.0078 0.0303 0.2367
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0303 0.4847
Chlamydia trachomatis proline--tRNA ligase 0.0048 0.0148 0.2978
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Loa Loa (eye worm) hypothetical protein 0.0064 0.023 0.0524
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0043 0.0203
Echinococcus granulosus solute carrier family 22 0.0064 0.023 0.0292
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0107 0.0468
Trichomonas vaginalis glucose transporter, putative 0.0141 0.0634 0.2785
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0046 0.0017
Schistosoma mansoni lysyl-tRNA synthetase 0.0102 0.0427 0.0542
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0059 0.0259
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0155 0.0329
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0064 0.023 1
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0099 0.0182
Echinococcus multilocularis neuropeptide s receptor 0.0489 0.2451 0.3314
Schistosoma mansoni hypothetical protein 0.0155 0.0705 0.0921
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0137 0.061 0.2679
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0414 0.1004
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0099 0.0114
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.006 0.007
Echinococcus multilocularis chromobox protein 1 0.0069 0.0256 0.0327
Trypanosoma brucei THT1 - hexose transporter, putative 0.0141 0.0634 0.4296
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0414 0.1004
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0303 0.2001
Brugia malayi Bromodomain containing protein 0.0029 0.0046 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.006 0.0041
Loa Loa (eye worm) hypothetical protein 0.0111 0.0476 0.1164
Mycobacterium ulcerans hypothetical protein 0.0078 0.0303 0.4102
Schistosoma mansoni protein kinase 0.0139 0.0625 0.0811
Loa Loa (eye worm) major facilitator superfamily transporter 0.0064 0.023 0.0524
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0159 0.0728 0.4949
Mycobacterium ulcerans beta-lactamase 0.0078 0.0303 0.4102
Plasmodium vivax hexose transporter 0.0456 0.2276 0.2253
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.014 0.0625 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.014 0.0625 0.0925
Onchocerca volvulus 0.003 0.0054 0.007
Schistosoma mansoni inositol monophosphatase 0.004 0.0107 0.0105
Onchocerca volvulus 0.0064 0.023 0.1698
Mycobacterium ulcerans hypothetical protein 0.0157 0.0718 1
Leishmania major glucose transporter, lmgt1 0.0141 0.0634 0.4296
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0303 0.1163
Plasmodium falciparum lysine--tRNA ligase 0.0102 0.0427 0.0399
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.2112 0.2853
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0303 0.4102
Trichomonas vaginalis sugar transporter, putative 0.0064 0.023 0.1012
Brugia malayi Pre-SET motif family protein 0.0208 0.0981 0.2481
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2276 0.3076
Schistosoma mansoni sugar transporter 0.0064 0.023 0.0274
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0303 0.2001
Brugia malayi hypothetical protein 0.0153 0.0693 0.173
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0303 0.0712
Loa Loa (eye worm) hypothetical protein 0.0137 0.061 0.1513
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0137 0.061 0.0808
Onchocerca volvulus 0.0064 0.023 0.1698
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0107 0.0643
Toxoplasma gondii ABC1 family protein 0.0078 0.0303 0.0437
Echinococcus granulosus geminin 0.019 0.0888 0.1187
Loa Loa (eye worm) hypothetical protein 0.0102 0.0427 0.1036
Echinococcus granulosus chromobox protein 1 0.0069 0.0256 0.0327
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0099 0.0095
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0046 0.0042
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0026 0.0029 0.0221
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0059 0.0259
Echinococcus granulosus chromobox protein 1 0.0069 0.0256 0.0327
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0303 0.1163
Echinococcus granulosus lysyl tRNA synthetase 0.0102 0.0427 0.056
Loa Loa (eye worm) inositol-1 0.004 0.0107 0.0201
Schistosoma mansoni hypothetical protein 0.019 0.0888 0.117

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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